Whole Exome Sequencing and Molecular Modeling of a Missense Variant in That Segregates with Disease in a Family with Chronic Urticaria and Angioedema.
- Antoneicka L Harris,
- Patrick R Blackburn,
- John E Richter,
- Jennifer M Gass,
- Thomas R Caulfield,
- Ahmed N Mohammad,
- Paldeep S Atwal
Case Rep Genet 2018 22;2018:6968395. Epub 2018 Feb 22.
Center for Individualized Medicine, Mayo Clinic, Jacksonville, FL, USA.
Chronic urticaria is a common condition characterized by recurrent hives lasting several weeks or months and is usually idiopathic. Approximately half of the individuals with chronic urticaria will present with episodes of angioedema that can be severe and debilitating. In this report, we describe a 47-year-old Hispanic male who presented initially for an evaluation of chronic hives following hospitalization due to hive-induced anaphylaxis. Read More