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Cardiol J 2019 Apr 17. Epub 2019 Apr 17.

Heart Center, Tampere University Hospital and Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, 33520 Tampere, Finland.

Background: Long-term outcome of the three categories of acute coronary syndrome (ACS) in real-life patient cohorts is not well known. The objective of this study was to survey the 10-year outcome of an ACS patient cohort admitted to a university hospital and to explore factors affecting the outcome.

Methods: A total of 1188 consecutive patients (median age 73 years) with ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI) or unstable angina pectoris (UA) in 2002-2003 were included and followed up for ≥ 10 years. Read More

Korean J Radiol 2019 May;20(5):719-728

Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea.

Objective: To investigate the diagnostic validity of coronary computed tomography angiography (cCTA) in vasospastic angina (VA) and factors associated with discrepant results between invasive coronary angiography with the ergonovine provocation test (iCAG-EPT) and cCTA.

Materials And Methods: Of the 1397 patients diagnosed with VA from 2006 to 2016, 33 patients (75 lesions) with available cCTA data from within 6 months before iCAG-EPT were included. The severity of spasm (% diameter stenosis [%DS]) on iCAG-EPT and cCTA was assessed, and the difference in %DS (Δ%DS) was calculated. Read More

Kardiologiia 2019 Apr 13;59(3S):30-35. Epub 2019 Apr 13.

Research Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (IIPM - Branch of IC G SB RAS); B. Bogatkov Str., 175/1, Novosibirsk, 630089, Russian Federation.

The aim of the study was to investigate the prevalence of angina pectoris (AP) according to the standardized epidemiological questionnaire of Rose in the population of 25-45 years of Novosibirsk and to identify its association with some lipid and non-lipid risk factors for coronary heart disease (CHD).

Material And Methods: Cross-sectional survey of the population aged 25-45 in Novosibirsk was carried out. The study included 1439 people (656 men and 783 women). Read More

Zhongguo Zhong Yao Za Zhi 2019 Mar;44(5):1041-1047

Institution of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences Beijing 100700,China.

To analyze the medication features and regularity of prescriptions of traditional Chinese medicines in treating patients with coronary heart disease angina pectoris based on the launched Chinese patent medicines. In the article,we collected all of the launched Chinese patent medicines for treating coronary heart disease and angina pectoris from the Chinese patent medicine value assessment information database,and set up a medical record normalized database,then carried out the classification of syndromes. The medication features and prescription rules for angina pectoris were analyzed by frequency statistics and association rules(IBM SPSS Modeler 14. Read More

Lipids Health Dis 2019 Apr 13;18(1):99. Epub 2019 Apr 13.

Department of Cardiology, 12th ward, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Clinical center for coronary heart disease, Capital Medical University, Beijing, 100029, China.

Objective: The value of atherogenic index of plasma (AIP) as a predictive biomarker for coronary artery disease (CAD) remains controversial. In addition, whether AIP is associated with the risk of acute coronary syndrome (ACS) in very young adults has not been well established.

Methods: We consecutively collected very young adults (≤35 years of age) undergoing coronary angiography (CAG) at Anzhen Hospital, between January 2008 and December 2017. Read More

A A Pract 2019 Apr 11. Epub 2019 Apr 11.

Vascular Surgery, Hadassah - Hebrew University Medical Center, Jerusalem, Israel.

We present a patient who was admitted for carotid endarterectomy due to tight carotid stenosis and recent amaurosis fugax. His medical history included significant coronary artery disease with stable angina pectoris, hypertension with wide pulse pressure, chronic renal failure, and anemia. During preparation for surgery, the patient developed type 2 myocardial infarction with prolonged chest pain, ST depressions on electrocardiogram, and significant troponin elevations. Read More

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1053-1057

Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.

To evaluate the long-term clinical outcomes of multiple arterial off-pump coronary artery bypass grafting (OPCAB) on left main coronary artery or multivessel disease. A total of 329 patients [303 males and 26 females, with a mean age of (55.1±9. Read More

Biosci Rep 2019 Apr 12. Epub 2019 Apr 12.

Henan Province Hospital of Traditional Chinese Medicine, Zhengzhou, China

We assessed the relationship between the volume of epicardial adipose tissue and long-term outcomes in patients with coronary heart disease (CHD) undergoing percutaneous coronary intervention (PCI). The patients with CHD were followed for at least 2 years after PCI. The epicardial adipose tissue volume (EATV) was measured using multi-slice computed tomography. Read More

Int J Cardiol 2019 Mar 21. Epub 2019 Mar 21.

Department of Cardiology, Tel Aviv Medical Center and Sackler School of Medicine, Tel Aviv University, Israel. Electronic address:

Objective: Evaluating the impact of Coronary sinus (CS) narrowing on diastolic function.

Background: Narrowing of the CS is an emerging therapy for refractory angina pectoris, improving perfusion to the ischemic subendocardium and relieving ischemia and angina. It was speculated that increased CS pressure might cause interstitial myocardial edema and diastolic dysfunction. Read More

Cardiovasc Revasc Med 2019 Mar 31. Epub 2019 Mar 31.

Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Kanagawa, Japan.

Percutaneous coronary intervention (PCI) for patients with thrombocytopenia presents a difficult problem in that dual antiplatelet therapy (DAPT) after drug-eluting stent (DES) implantation is not suitable. This first case report describes our patient with angina pectoris and thrombocytopenia who we successfully treated with PCI after partial splenic artery embolization (PSE). A 70-year-old Japanese male was transferred to our hospital because of acute decompensated heart failure (ADHF). Read More

PLoS One 2019 11;14(4):e0215209. Epub 2019 Apr 11.

Department of Biochemistry, Medical Faculty, University of Szeged, Szeged, Hungary.

Objective: The primary aim of this study was to examine whether markers of cell damage and of the psycho-neuroendocrino-inflammatory/immune (PNI) system could be associated in patients with stable coronary artery disease (CAD) on the next day following percutaneous coronary intervention (PCI).

Materials And Methods: Blood samples of 23 patients (18 men and five women, mean age 62.9 ± 10. Read More

Clin Toxicol (Phila) 2019 Apr 9:1-11. Epub 2019 Apr 9.

a Department of Emergency Medicine , University of California Davis Medical Center , Sacramento , CA , USA.

Introduction: Cannabis smoking can result in elevation of heart rate and blood pressure immediately after use, possibly from sympathetic nervous system stimulation and parasympathetic nervous system inhibition. Vascular inflammation, platelet activation, and carboxyhemoglobin generation have also been proposed as potential side effects of cannabis smoking. As such, an association between cannabis use and acute coronary syndrome has been postulated. Read More

Eur Rev Med Pharmacol Sci 2019 Mar;23(6):2570-2575

Department of Cardiology, Private Yucelen Hospital, Mugla, Turkey.

Objective: Inflammation plays an important role in the pathogenesis of atherosclerosis. The lymphocyte-to-monocyte ratio (LMR) may reflect a systemic inflammatory status. We investigated the association between the LMR and coronary artery disease (CAD) in patients with stable angina pectoris. Read More

Wien Klin Wochenschr 2019 Apr 8;131(7-8):165-173. Epub 2019 Apr 8.

Department for Cardiology, Hospital Hietzing, Wolkersbergenstraße 1, 1130, Vienna, Austria.

Objective: Assessment of treatment routine and outcome for ranolazine in clinical practice as second-line treatment for stable angina pectoris (AP).

Design And Setting: Multicenter, prospective, uncontrolled, non-interventional study at 88 sites including internal specialists, cardiologists, pneumologists, angiologists and primary care practices in Austria.

Participants: In this study 292 patients receiving ranolazine in the course of routine treatment on top of beta blockers or calcium channel blockers after failure of first-line therapy. Read More

Heart Vessels 2019 Apr 8. Epub 2019 Apr 8.

Department of Laboratory Medicine, The Second People's Hospital of Lianyungang, 41 East Hailian Road, Lianyungang, 222006, Jiangsu, People's Republic of China.

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a newly emerging biomarker with strong pro-inflammatory effects, and is an independent risk predictor of atherosclerotic plaque rupture and thrombosis. In addition, ischemic modified albumin (IMA) is another important marker for the evaluation of myocardial ischemia, and has been approved by the U.S. Read More

Atherosclerosis 2019 Mar 3;284:202-208. Epub 2019 Mar 3.

Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden; School of Health and Social Studies, Dalarna University, Falun, Sweden. Electronic address:

Background And Aims: Raised levels of serum endostatin, a biologically active fragment of collagen XVIII, have been observed in patients with ischemic heart disease but association with incident cardiovascular events in patients with stable coronary heart disease is uncertain.

Methods: The CLARICOR-trial is a randomized, placebo-controlled trial of stable coronary heart disease patients evaluating 14-day treatment with clarithromycin. The primary outcome was a composite of acute myocardial infarction, unstable angina pectoris, cerebrovascular disease or all-cause mortality. Read More

Cytokine Growth Factor Rev 2019 Mar 18. Epub 2019 Mar 18.

Leeds Institute of Cardiovascular & Metabolic Medicine, School of Medicine, University of Leeds, United Kingdom. Electronic address:

Angiogenesis is a tightly regulated activity that is vital during embryonic development and for normal physiological repair processes and reproduction in healthy adults. Pathological angiogenesis is a driving force behind a variety of diseases including cancer and retinopathies, and inhibition of angiogenesis is a therapeutic option that has been the subject of much research, with several inhibitory agents now available for medical therapy. Conversely, therapeutic angiogenesis has been mooted as having significant potential in the treatment of ischemic conditions such as angina pectoris and peripheral arterial disease, but so far there has been less translation from lab to bedside. Read More

Sci Rep 2019 Apr 5;9(1):5708. Epub 2019 Apr 5.

Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

The purpose of the present study was to assess whether 6-week ranolazine application on top of guideline-based treatment impacts on the arginine/NO pathway and urinary isoprostane 8-iso-PGF as marker of oxidative stress in patients directly after a myocardial infarction. 20 patients with unstable angina pectoris and proof of acute cardiac ischemia entered the study. 10 subjects received the study drug ranolazine in addition to standard treatment, the others received only standard treatment. Read More

Eur Heart J Suppl 2019 Mar 29;21(Suppl B):B25-B27. Epub 2019 Mar 29.

Vita Salute University, IRCCS Ospedale San Raffaele, Milano, Italy.

Hypertens Res 2019 May 5;42(5):650-659. Epub 2019 Apr 5.

Department of Preventive Medicine and Public Health, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, Fukuoka, 814-0180, Japan.

The target of diastolic blood pressure (DBP) remains controversial in patients with coronary artery disease (CAD). We systematically searched PubMed/Medline and the Cochrane Central database for randomized controlled trials (RCTs) assessing the efficacy and safety of reducing DBP in CAD patients from January 1965 to July 2017. Seven placebo-controlled RCTs enrolling 34,814 CAD patients who achieved DBP <80 mmHg were included in the drug-intervention group. Read More

EuroIntervention 2019 Apr 2. Epub 2019 Apr 2.

Department of Cardiology, The 2nd Affiliated Hospital of Harbin Medical University, and The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China.

Aims: To determine the prevalence and significance of plaque with a multilayered (ML) pattern in patients with acute coronary syndrome (ACS) vs stable angina pectoris (SAP) using OCT.

Methods And Results: 204 patients (144 ACS and 60 SAP) with OCT imaging of the culprit lesions before intervention were studied. ML plaques were identified by OCT as a plaque with multiple layers of distinct optical signals. Read More

Chin J Integr Med 2019 Apr 2. Epub 2019 Apr 2.

Department of Pathophysiology, Chinese PLA General Hospital, Beijing, 100853, China.

Objective: To assess the efficacy and safety of Taohong Siwu Decoction (, TSD), a Chinese herbal compound prescription, in patients with angina pectoris (AP).

Methods: Randomized clinical trials (RCTs) comparing TSD plus conventional treatment (CT) with CT plus placebo or CT only in the patients with AP were searched in PubMed, Cochrane Library, Excerpta Medica Database, Chinese National Knowledge Infrastructure, Chinese Biomedical Literature Database, Wanfang Database, Chinese Scientific Journal Database, Chinese Clinical Trial Registry and International Clinical Trial Registry from their inception to March 2017. The primary outcomes include a composite event of death, acute myocardial infarction (AMI), and target vessel revascularization. Read More

Complement Ther Med 2019 Apr 8;43:208-217. Epub 2019 Feb 8.

Department of Clinical Chinese Pharmacy, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100102, China. Electronic address:

Objective: The severity of angina pectoris has been recognized. It is believed that Chinese herbal injections have an outstanding clinical effect on this condition. This network meta-analysis was devised to investigate the comparative efficacy of eight Chinese herbal injections (Ciwujia injection, Dazhuhongjingtan injection, Huangqi injection, Shenfu injection, Shengmai injection, Shenmai injection, Shenqi Fuzheng injection, Yiqifumai injection) in the treatment of angina pectoris. Read More

Medicine (Baltimore) 2019 Mar;98(13):e15008

Department of Cardiology, Panyu Central Hospital.

Rationale: Transradial access (TRA) is common for cardiac catheterization, but radial artery spasm (RAS) is suggested to be highlighted. Severe radical artery spasm could be solved by a relative novel approach called "sheathless technique," using a Tiger diagnostic catheter.

Patient Concerns: A 73-year-old woman presented to our institution with a recurrent feeling of discomfort in her chest. Read More

J Atheroscler Thromb 2019 Mar 27. Epub 2019 Mar 27.

Cardiovascular Center, Yokosuka Kyosai Hospital.

Aim: Knowledge of subclinical plaque morphology and plaque distribution in the aorta in vivo remains unclear. This study aimed to increase the body of knowledge in this area.

Methods: We enrolled 37 consecutive patients with stable angina pectoris patients who underwent non-obstructive angioscopy for both the coronary artery and aorta immediately after percutaneous coronary intervention. Read More

Evid Based Complement Alternat Med 2019 19;2019:2721413. Epub 2019 Feb 19.

Key Laboratory of Formula of Traditional Chinese Medicine (Tianjin University of Traditional Chinese Medicine), Ministry of Education, China.

Objective: Danshen, the root of Bunge, is a traditional herbal medicine in China, which has been used to treat irregular menstruation, cold hernia, and abdominal pain for thousands of years. Danshen is frequently used in combination with drugs to treat cardiovascular diseases. Clopidogrel is a commonly used drug for treating coronary heart disease, but clopidogrel resistance restricts its development. Read More

Ren Fail 2019 Nov;41(1):118-125

g Department of Clinical Pharmacy , University of Michigan College of Pharmacy , Ann Arbor , MI , USA.

Purpose: Ranolazine is a novel anti-angina treatment approved in the United States for chronic stable angina. Ranolazine pharmacokinetics have not been studied previously in patients who receive maintenance hemodialysis. This study describes the pharmacokinetics of ranolazine and three major metabolites (CVT-2738, CVT-2512, CVT-2514) in patients receiving thrice weekly hemodialysis. Read More

J Card Surg 2019 Mar 21. Epub 2019 Mar 21.

Second Department of Surgery, Yamagata University Faculty of Medicine, Yamagata, Japan.

Here we report a rare case of atypical Kawasaki disease (KD) in a patient presenting with systemic arteritis affecting the coronary arteries, brain, and internal mammary arteries (IMAs). A 25-year-old man was referred to our institute with angina pectoris. Coronary angiography revealed coronary artery aneurysms and triple-vessel disease. Read More

Med Sci Monit 2019 Mar 22;25:2112-2121. Epub 2019 Mar 22.

Department of Cardiology, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Qilu Hospital affiliated to Shandong University, Jinan, Shandong, China (mainland).

BACKGROUND Our research was designed to investigate the relationship of spleen tyrosine kinase (Syk) and inflammatory factors with coronary heart disease (CHD) and the risk factors of CHD. MATERIAL AND METHODS In our study, 226 patients were enrolled, from October 2017 to March 2018. Clinical and biochemical data were collected. Read More

J Cardiol 2019 Mar 18. Epub 2019 Mar 18.

Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama City, Japan.

Background: Malondialdehyde-modified low-density lipoprotein (MDA-LDL) is a predictive marker of cardiovascular events in patients with stable angina pectoris. However, little is known about this marker in patients with acute coronary syndrome (ACS). We investigated the prognostic relevance of MDA-LDL to cardiovascular outcomes in patients with ACS. Read More

Nan Fang Yi Ke Da Xue Xue Bao 2019 02;39(2):235-240

Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.

Objective: To analyze the correlation of lipoprotein(a) [Lp(a)] with the clinical stability and severity of coronary artery stenosis in patients with coronary artery disease (CAD).

Methods: A total of 531 patients undergoing coronary angiography in Nanfang Hospital between January, 2013 and December, 2016 were enrolled in this study. At the cutoff Lp(a) concentration of 300 mg/L, the patients were divided into high Lp(a) group (=191) and low Lp(a) group (=340). Read More

Scand J Clin Lab Invest 2019 Mar 20:1-9. Epub 2019 Mar 20.

b Department of Cardiology , Rigshospitalet, University of Copenhagen , Copenhagen , Denmark.

Coronary microvascular dysfunction (CMD) is associated with a poor prognosis even in absence of obstructive coronary artery disease. CMD can be assessed as a myocardial blood flow reserve by positron emission tomography (PETMBFR) and as coronary flow velocity reserve by transthoracic Doppler echocardiography (TTDECFVR). Impaired first-pass perfusion assessed by cardiac magnetic resonance (CMR) is an early sign of ischemia. Read More

Cardiovasc Diagn Ther 2019 Feb;9(1):1-7

Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China.

Background: Recent studies have found that adropin is associated with coronary artery disease (CAD). This meta-analysis sought to assess the relationship between serum adropin level and CAD.

Methods: Online databases including the Cochrane Library, PubMed, EMbase, Ovid, CBM, CNKI, VIP and WanFang Data were electronically searched for the clinical study concerning the relationship between serum adropin levels and CAD, including acute myocardial infarction (AMI), unstable angina pectoris (UAP), and stable angina pectoris (SAP). Read More

Int J Angiol 2019 Mar 2;28(1):50-56. Epub 2019 Jan 2.

Faculty of Social Sciences, University of Tampere, Tampere, Finland.

A prevalence of diabetes is increasing among the patients undergoing coronary artery bypass grafting (CABG). Data on whether health-related quality of life improves similarly after CABG in diabetics and nondiabetics are limited. We assessed long-term mortality and changes in quality of life (RAND-36 Health Survey) after CABG. Read More

J Cardiol 2019 Mar 14. Epub 2019 Mar 14.

Department of Cardiology, Japanese Red Cross Musashino Hospital, Tokyo, Japan.

Background: Malnutrition is associated with a poor prognosis in heart failure, angina pectoris, and peripheral artery disease. However, the clinical importance of the preprocedural nutrition status of patients requiring pacemaker implantation (PMI) for bradycardia is unclear.

Methods: We retrospectively enrolled 521 patients (median 79 years) who underwent their first PMI between January 1, 2012 and June 30, 2017. Read More

Korean J Intern Med 2019 Mar 19. Epub 2019 Mar 19.

Department of Internal Medicine, Korea University Anam Hospital, Seoul, Korea.

Background/aims: Chest pain in patients with obstructive coronary artery disease (OCAD) is affected by several social factors. The gender-based differences in chest pain among Koreans have yet to be investigated.

Methods: The study consecutively enrolled 1,549 patients (male/female, 514/1,035; 61 ± 11 years old) with suspected angina. Read More

J Cardiothorac Surg 2019 Mar 14;14(1):60. Epub 2019 Mar 14.

Department of Thoracic Surgery, Shengjing Hospital of China Medical University, Shenyang, 110004, China.

Background: Atrial fibrillation (AF) is a common complication after radical surgery of esophageal cancer. The aim of this study was to explore AF risk factors after radical surgery of esophageal carcinoma.

Method: The data of 335 patients with esophageal cancer who were admitted in our hospital from January 2014 to August 2016 for the first time were retrospectively analyzed. Read More

Clin Hypertens 2019 1;25. Epub 2019 Mar 1.

1Division of Cardiology, Department of Internal Medicine, Kosin University College of Medicine, 34, Amnam-dong, Seo-gu, Busan, 602-702 Korea.

Background: Angina pectoris with a normal coronary angiogram, termed microvascular angina (MVA), is an important clinical entity; however, its causes remain unclear. Autonomic dysfunction is one of the possible causes. Therefore, this study aimed to investigate parasympathetic dysfunction assessed by heart rate recovery (HRR) and increased sympathetic activity assessed by exaggerated blood pressure (BP) response (EBPR) to exercise in MVA. Read More

JAMA Cardiol 2019 Mar 13. Epub 2019 Mar 13.

Department of Cardiovascular and Thoracic Sciences, Fondazione Policlinico A. Gemelli, Istituto di Ricovero e Cura a Carattere Scientifico, Università Cattolica Sacro Cuore, Rome, Italy.

Importance: At one end of the coronary artery disease (CAD) spectrum, there are patients with multiple recurrent acute coronary syndromes (rACS), and at the other end there are those with long-standing clinical stability. Predicting the natural history of these patients is challenging because unstable plaques often heal without resulting in ACS.

Objective: To assess in vivo the coronary atherosclerotic phenotype as well as the prevalence and characteristics of healed coronary plaques by optical coherence tomography (OCT) imaging in patients at the extremes of the CAD spectrum. Read More

Dtsch Arztebl Int 2019 Jan;116(4):47-53

Department of Cardiology, Klinikum Würzburg-Mitte, Juliusspital, Würzburg; Department of Thoracic and Cardiovascular Surgery, Saarland University Hospital, Homburg/Saar; University of Paris Descartes, Sorbonne Paris Cité, Paris, France.

Background: Hypertrophic cardiomyopathy (HCM) is caused by mutations in a number of genes. Its prevalence is 0.2% to 0. Read More

Kardiologiia 2019 Mar 7;59(2S):56-68. Epub 2019 Mar 7.

I. M. Sechenov First Moscow State Medical University (Sechenov University)..

Relevance: Radiation therapy (RT) plays an important role in oncology, improving the immediate and long-term results of treatment of a number of tumors. One of the most significant complications of RT are lesions of the heart valves.

Objective: To study the variants of valve damage that occur in patients who received radiation therapy for cancer. Read More

Swiss Med Wkly 2019 02 10;149:w20012. Epub 2019 Mar 10.

Swiss Childhood Cancer Registry, Institute of Social and Preventive Medicine (ISPM), University of Bern, Switzerland / Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Switzerland.

Background And Aims: Cardiovascular diseases (CVD) increase late morbidity and mortality in survivors of acute lymphoblastic leukaemia (ALL). We compared the risk of CVD in ALL survivors to siblings, examined time trends, quantified treatment-related risks, and investigated whether risk extends beyond patients treated with anthracyclines and chest radiotherapy.

Methods: The Swiss Childhood Cancer Survivor Study assessed CVD by patient questionnaire in 5-year ALL survivors diagnosed between 1976 and 2005 and their siblings. Read More

J Cardiothorac Surg 2019 Mar 8;14(1):52. Epub 2019 Mar 8.

Department of Cardiac Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), 1011, Lausanne, Switzerland.

Background: Coronary artery aneurysms (CAA) are defined as localized coronary artery dilations more than 1.5 times the diameter of the adjacent segments [1]. Giant coronary aneurysms (GCAA) are unusual and aneurysms on the left side are even rarer. Read More

J Med Case Rep 2019 Mar 9;13(1):78. Epub 2019 Mar 9.

Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Banten, Indonesia.

Background: Coronary artery ectasia is characterized by an abnormal dilatation of the coronary arteries. Coronary artery ectasia is observed in 3-8% of patients undergoing coronary angiography and sometimes leads to acute coronary syndrome regardless of the presence or absence of coronary stenosis or atrial fibrillation.

Case Presentation: A 61-year-old Indonesian man presented with typical angina that began 1 week before admission and had worsened 3 hours prior to admission. Read More

BMC Psychiatry 2019 Mar 5;19(1):85. Epub 2019 Mar 5.

Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, No.106 Zhongshan Er Road, Guangzhou, 510080, People's Republic of China.

Background: Depression and anxiety are prevalent and associated with a worse prognosis in coronary heart disease (CHD) patients. However, the influence of disease severity on mood symptoms is unknown. The specific associations of mood symptoms with NYHA classes remain unexplored. Read More

Zhonghua Xin Xue Guan Bing Za Zhi 2019 Feb;47(2):117-122

Cardiovascular Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.

To explore the predictive value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) on admission on left ventricular ejection fraction (LVEF) and the in-hospital major adverse cardiac and cerebrovascular events (MACCE) in hospitalized patients with unstable angina (UA). Data of 2 972 consecutive hospitalized patients with UA in Beijing Friendship Hospital from January 2013 to September 2017 were retrospective analyzed. Patients were divided into 4 groups according to the level of NT-proBNP on admission: 733 cases with NT-proBNP lower than 61 ng/L, 749 cases with NT-proBNP between 61 and 133 ng/L, 747 cases with NT-proBNP between 133 and 326 ng/L, and 743 cases with NT-proBNP higher than 326 ng/L. Read More

Medicine (Baltimore) 2019 Mar;98(9):e14708

Key Laboratory of Chinese Internal Medicine, Ministry of Education and Beijing.

Background: Coronary heart disease angina is a very common cardiovascular disease, which not only causes personal health problems, but also a serious burden on the social economy. Xuefu Zhuyu Decoction (XFZYD) has been widely adapted to clinical practice for people with coronary heart disease angina. At present, it is necessary to update the existing research, re-evaluate the effectiveness and safety of XFZYD, and provide the latest evidence for coronary heart disease angina. Read More

Medicine (Baltimore) 2019 Mar;98(9):e14638

Gansu University of Chinese Medicine.

Background: Chronic stable angina (CSA) resulted in a considerable burden for both individuals and the society. In this study we aimed to critically evaluate the effectiveness and safety of Compound salvia pellet compared with nitrates in the treatment of Chronic Stable Angina (CSA) pectoris, and to provide more credible evidence for clinical practice.

Methods: A comprehensive and exhaustive search strategy was formulated to identify potential RCTs of compound salvia pellet for CSA in international and Chinese databases from their inception to July 4th, 2018. Read More

Open Heart 2019 2;6(1):e000870. Epub 2019 Feb 2.

Division of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

Aim: Angina pectoris in the absence of obstructive coronary artery disease (CAD) is common and is associated with poor quality of life (QOL). Coronary microvascular endothelial dysfunction is associated with myocardial ischaemia and is a common cause of angina. We hypothesise that evaluation of coronary endothelial function, its diagnosis and treatment will favourably impact QOL in patients with angina symptoms and non-obstructive CAD. Read More