16,763 results match your criteria Aneurysmal Bone Cyst Imaging


Aneurysmal Subarachnoid Hemorrhage Onset Alters Pyruvate Metabolism in Poor-Grade Patients and Clinical Outcome Depends on More: A Cerebrospinal Fluid Metabolomic Study.

ACS Chem Neurosci 2018 Dec 6. Epub 2018 Dec 6.

Cerebral metabolism alterations influence cerebrospinal fluid (CSF) composition, and is sensitive to brain injury. In subarachnoid hemorrhage (SAH) patients, Fisher scale, Hunt-Hess scale and World Federation of Neurological Societies (WFNS) grading scales evaluating SAH severity are inadequate to predict long-term outcome; therefore, in an effort to determine metabolite pattern disparity and discover corresponding biomarkers, we designed an untargeted CSF metabolomic research covering a board range of metabolites of SAH patients with different severity and outcome. The present study demonstrated SAH altered cerebrospinal fluid metabolome involving carbohydrate, lipid and amino acids metabolism. Read More

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December 2018
1 Read

Histone deacetylase inhibition disturbs the balance between ACE and chymase expression in endothelial cells: a potential mechanism of chymase activation in preeclampsia.

Hypertens Res 2018 Dec 5. Epub 2018 Dec 5.

Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, USA.

Chymase is a major angiotensin-converting enzyme (ACE)-independent angiotensin convertase, and its expression is upregulated in the maternal vascular endothelium in preeclampsia, a hypertensive disorder in human pregnancy. Increased chymase-dependent angiotensin II generation has been reported in several cardiovascular diseases, including atherosclerosis and aneurysmal lesions. However, it remains unclear how chymase is activated. Read More

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December 2018

Clazosentan for aneurysmal subarachnoid hemorrhage: An updated meta-analysis with trial sequential analysis.

World Neurosurg 2018 Nov 30. Epub 2018 Nov 30.

Institute of New Frontier Research, Hallym University College of Medicine, Chuncheon, Korea; Department of Neurosurgery, Hallym University College of Medicine, Chuncheon, Korea. Electronic address:

Object: Clazosentan, an endothelin-receptor-antagonist, reduced vasospasm and delayed-ischemic-neurological-deficit (DIND) but did not improve outcome following subarachnoid hemorrhage (SAH) in clinical trials. However, a lack of dose-dependent analysis and potential overestimation of clazosentan's effect are concerning. We employ stratified analysis and trial-sequential-analysis (TSA) of existing data to investigate the effects of clazosentan on SAH outcome. Read More

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November 2018
1 Read

Type II endoleak model creation and intraoperative aneurysmal sac embolization with -butyl cyanoacrylate-lipiodol-ethanol mixture (NLE) in swine.

Quant Imaging Med Surg 2018 Oct;8(9):894-901

Department of Radiology, Wakayama Medical University, Wakayama, Japan.

Background: The purpose of this study was to evaluate the feasibility of type II endoleak model creation and efficacy of intraoperative aneurysmal sac embolization using -butyl-2-cyanoacrylate-lipiodol-ethanol mixture (NLE) for type II endoleak in swine.

Methods: In six swine (mean body weight 53.5 kg), abdominal aortic aneurysm (AAA) was created and then end-to-side anastomosis between the left renal artery and AAA sac was performed. Read More

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October 2018

Does Neuroprotection Still Have a Role in Injured Brain Following Aneurysmal Subarachnoid Haemorrhage?

Authors:
Giovanni Grasso

Turk J Anaesthesiol Reanim 2018 Dec 1;46(6):478-479. Epub 2018 Dec 1.

Department of Experimental Biomedicine and Clinical Neurosciences (BIONEC), University of Palermo, Palermo, Italy.

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December 2018

Outcome assessment following aneurysmal subarachnoid hemorrhage - need for a comprehensive tool.

Authors:
Girish Menon

Neurol India 2018 Nov-Dec;66(6):1718-1720

Department of Neurosurgery, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.

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December 2018

Neurological, neuropsychological, and functional outcome after good grade aneurysmal subarachnoid hemorrhage.

Neurol India 2018 Nov-Dec;66(6):1713-1717

Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Background: There is a paucity of information about which impairments, cognitive or neurological, determine the functional outcome after aneurysmal subarachnoid hemorrhage (SAH). The present study aims to determine the relative contributions of each of the above impairments for determining the functional outcome after SAH.

Materials And Methods: This is a prospective observational study including patients with aneurysmal SAH. Read More

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December 2018

Endoluminal Atherosclerotic Plaque Debulking Using Enzymatic and Ultrasonic Energy.

J Surg Res 2019 Jan 6;233:335-344. Epub 2018 Sep 6.

Department of Surgery, Northwestern University, Chicago, Illinois; Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. Electronic address:

Background: Current procedures to treat severe atherosclerosis are traumatic to the arterial wall and often result in restenosis due to neointimal hyperplasia. We developed a novel therapy using a specially designed double occlusion balloon catheter, ultrasonic wire, and enzymatic digestion solution to atraumatically debulk atherosclerotic plaques.

Materials And Methods: A combination of different enzymes, chemicals, and treatment conditions were evaluated for its effect at reducing atherosclerotic plaque harvested from human carotid artery endarterectomies ex vivo. Read More

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January 2019

Management of intracranial haemorrhage, unruptured aneurysms and arteriovenous malformations during and after pregnancy.

Curr Opin Neurol 2018 Nov 30. Epub 2018 Nov 30.

Medicina Vascolare e D'Urgenza-Stroke Unit, Ospedale Santa Maria della Misericordia, Università di Perugia, Perugia, Italy.

Purpose Of Review: The absolute risk of pregnancy-associated intracranial haemorrhage (ICH) has been reported to be relatively low and often associated with high risks of life-long disabilities and mortality. The aim of this narrative review was obtaining a better understanding of the current management practices for ICH, unruptured aneurysms and/or arteriovenous malformations during pregnancy, as well as the effects of future pregnancies, and the uses of oral contraceptive or HRT.

Recent Finding: General guidelines for the management of ICH are used for pregnant women but additional expedient and thorough evaluation of foetal viability and its gestational age are requested. Read More

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November 2018

Subarachnoid Hemorrhage.

Continuum (Minneap Minn) 2018 Dec;24(6):1623-1657

Purpose Of Review: This article reviews the epidemiology, clinical presentation, diagnosis, and management of patients with aneurysmal subarachnoid hemorrhage (SAH). SAH is a type of hemorrhagic stroke and is a neurologic emergency with substantial morbidity and mortality. This article reviews the most common and potentially life-threatening neurologic and medical complications to promote their early recognition and prevent secondary brain injury. Read More

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December 2018
1 Read

Hypernatremia is associated with poorer outcomes following aneurysmal subarachnoid hemorrhage: a nationwide inpatient sample analysis.

J Neurosurg Sci 2018 Dec 5. Epub 2018 Dec 5.

Department of Neurosurgery, State University of New York Upstate, Syracuse, NY, USA.

Background: Hypernatremia is one of the most common electrolyte disturbances following aneurysmal subarachnoid hemorrhage (aSAH) and has been correlated with increased mortality in single institution studies. We investigated this association using a large nationwide healthcare database.

Methods: We performed a retrospective analysis of adults between 2002 and 2011 with a primary diagnosis of aSAH using the Nationwide Inpatient Sample (NIS). Read More

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December 2018

Successful Endovascular Aneurysm Repair For Brucella Mycotic Aneurysm Acquired From Ingestion Of Sheep Placenta.

Ann Vasc Surg 2018 Nov 27. Epub 2018 Nov 27.

Division of Vascular Surgery, Department of Surgery, University of Hong Kong Shenzhen Hospital, Shenzhen, Guangdong, China; Division of Vascular & Endovascular Surgery, Department of Surgery, University of Hong Kong Medical Centre, South Wing, 14(th) Floor K Block, Queen Mary Hospital, Hong Kong.

An aortic aneurysm infected by Brucella is rarely seen. In this case report, we describe a Brucella mycotic abdominal aortic aneurysm acquired from ingestion of sheep placenta. Clinical symptoms included fever, fatigue, and abdominal pain. Read More

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November 2018

Nationwide analysis of hospital-to-hospital transfer in patients with aneurysmal subarachnoid hemorrhage requiring aneurysm repair.

Authors:

J Neurosurg 2018 Oct 1:1-8. Epub 2018 Oct 1.

OBJECTIVEAneurysmal subarachnoid hemorrhage (aSAH) has devastating consequences. The association between higher institutional volumes and improved outcomes for aSAH patients has been studied extensively. However, the literature exploring patterns of transfer in this context is sparse. Read More

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October 2018

Ruptured intracranial aneurysm in a patient with autosomal recessive polycystic kidney disease.

Authors:

J Neurosurg Pediatr 2018 Oct 1:1-5. Epub 2018 Oct 1.

Aneurysmal rupture can result in devastating neurological consequences and can be complicated by comorbid disease processes. Patients with autosomal recessive polycystic kidney disease (ARPKD) have a low rate of reported aneurysms, but this may be due to the relative high rate of end-stage illnesses early in childhood. Authors here report the case of a 10-year-old boy with ARPKD who presented with a Hunt and Hess grade V subarachnoid hemorrhage requiring emergency ventriculostomy, embolization, and decompressive craniectomy. Read More

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October 2018
3 Reads

Testing the Medina embolization device in experimental aneurysms.

Authors:

J Neurosurg 2018 Oct 1:1-9. Epub 2018 Oct 1.

OBJECTIVEThe Medina embolization device (MED) is a novel, braided self-expanding endovascular device designed to occlude aneurysms by constructing an in situ intrasaccular flow diverter. Although a single device can be positioned at the neck of simple spherical in vitro aneurysms, the best way to occlude more complex in vivo aneurysms (using multiple MEDs or a combination of MEDs and platinum coils) is currently unknown.METHODSFifty-two aneurysms of 3 different types were created in 31 canines, yielding 48 patent aneurysms. Read More

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October 2018

Association between vasoactive peptide urotensin II in plasma and cerebral vasospasm after aneurysmal subarachnoid hemorrhage: a potential therapeutic target.

Authors:

J Neurosurg 2018 Oct 1:1-11. Epub 2018 Oct 1.

OBJECTIVECerebral vasospasm (VS) is a severe complication of aneurysmal subarachnoid hemorrhage (SAH). Urotensin II (UII) is a potent vasoactive peptide activating the urotensin (UT) receptor, potentially involved in brain vascular pathologies. The authors hypothesized that UII/UT system antagonism with the UT receptor antagonist/biased ligand urantide may be associated with post-SAH VS. Read More

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October 2018

Gastrostomy tube placement increases the risk of ventriculoperitoneal shunt infection: a multiinstitutional study.

Authors:

J Neurosurg 2018 Nov 1:1-6. Epub 2018 Nov 1.

OBJECTIVEGastrostomy tube placement can temporarily seed the peritoneal cavity with bacteria and thus theoretically increases the risk of shunt infection when the two procedures are performed contemporaneously. The authors hypothesized that gastrostomy tube placement would not increase the risk of ventriculoperitoneal shunt infection. The object of this study was to test this hypothesis by utilizing a large patient cohort combined from multiple institutions. Read More

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November 2018

Proposed Classification System for Retinal Capillary Angiomatosis.

Ophthalmic Res 2018 Nov 29:1-5. Epub 2018 Nov 29.

Retinal angiomas are rare tumors that develop within the vascular bed of the retina. Their occurrence may be sporadic or as part of the multisystem disorder called von Hippel-Lindau disease. It is well established in literature that retinal angiomas have a natural history of evolving as small aneurysmal dilatations and progressing to vision-threatening retinal detachments. Read More

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November 2018

An Update on Efficacy and Safety Profile of Clazosentan in Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage: A Meta-Analysis.

World Neurosurg 2018 Nov 26. Epub 2018 Nov 26.

Department of Neurosurgery, Linyi Central Hospital, Linyi, Shandong, China. Electronic address:

Aims: The present meta-analysis was conducted to provide an update on the efficacy and safety profile of clazosentan with different doses in aSAH.

Methods: We performed a comprehensive and electronic search of the following databases updated to September, 2018: the Cochrane library, Embase and PubMed, to identify relevant clinical trials. Trials of the effectiveness of clazosentan in treating cerebral vasospasm after aSAH were studied, of which the main outcomes included new cerebral infarction (NCI), delayed ischemic neurological deficit (DIND), vasospasm associated with morbidity/mortality (M/M), angiographic vasospasm, rescue therapy and adverse events. Read More

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November 2018
2 Reads

Ultrasound guided angioplasty of arteriovenous fistulas for hemodialysis: Benefits and limitations.

Ann Vasc Surg 2018 Nov 26. Epub 2018 Nov 26.

Service de chirurgie cardiovasculaire et thoracique, CHU François Miterrand, Dijon, France. Electronic address:

Background: Ultrasound-guided percutaneous angioplasty of arteriovenous fistulas (AVFs) makes it possible to avoid contrast agents and X-rays, to optimize the puncture site and to locate some stenoses on the fistulography, but is it really useful? Our objective was to report the results of our experience.

Material And Methods: Between November 2012 and November 2017, all the patients treated according to this method in our center were collected retrospectively. The surgical indications were an insufficient maturation of the AVF, an increase in the venous pressure, an inadequate outflow, difficulties in puncture, a prolonged bleeding time, a flow drop, or an aneurysmal evolution. Read More

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November 2018
3 Reads

Three cases of large-diameter true brachial and axillary artery aneurysm and a review of the literature.

Ann Vasc Surg 2018 Nov 26. Epub 2018 Nov 26.

Department of Cardiovascular Surgery, MD, Manisa Celal Bayar University, Manisa, Turkey.

Aneurysms of the upper extremity mostly originate from trauma, mycotic lesions, thoracic outlet syndrome, previous arteriovenous fistulae and atherosclerosis. True aneurysms of the brachial and axillary artery are encountered rarely. They can be diagnosed by simple physical examination as a pulsatile mass. Read More

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November 2018
1 Read

An atypical case of pulmonary embolism from a jugular vein.

Echo Res Pract 2018 Dec;5(4):K67-K72

University of Medicine and Pharmacy, Carol Davila, Bucharest, Romania.

Neck venous malformations and their potentially life-threatening complications are rarely reported in the available literature. Cases of aneurysmal or hypo-plastic jugular vein thrombosis associated with systemic embolization have not been frequently reported. We present the case of a 60-year-old male, without any known risk factors for thromboembolic disease, admitted for sudden onset dyspnea. Read More

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December 2018
5 Reads

Dropping the Hammer: An Uncommon Case of Right-Hand Pain in a Professional Hockey Player.

Sports Health 2018 Nov 29:1941738118816050. Epub 2018 Nov 29.

Texas Orthopaedic Associates, Dallas, Texas.

A 26-year-old, right-handed male professional hockey player presented for a second opinion with dysesthesia of the tips of his right third, fourth, and fifth fingers after 2 previous incidents of hyperextension injuries to his right wrist while holding his hockey stick. Radiographs and computed tomography scans were negative for fracture. After magnetic resonance angiography and Doppler ultrasound imaging, the athlete was diagnosed with hypothenar hammer syndrome (HHS) with ulnar artery aneurysm and thrombosis. Read More

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November 2018

RETINAL CAPILLARY MACROANEURYSMS.

Retina 2018 Nov 21. Epub 2018 Nov 21.

Department of Ophthalmology, Hospital Universitari de Bellvitge, Barcelona, Spain.

Purpose: To investigate eyes with solitary large aneurysms arising from retinal capillaries.

Methods: Consecutive patients with aneurysms greater than 200 µm in diameter were evaluated with a comprehensive ophthalmologic examination including optical coherence tomography, optical coherence tomography angiography, and fluorescein angiography. The aneurysms were solitary in the sense, and there was only one aneurysm larger than the threshold diameter and a few or no other aneurysms. Read More

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November 2018

Arterial Aneurysmal Degeneration With Venous Varicosity Following Ligation of an Arteriovenous Fistula in a Kidney Transplant Recipient.

Vasc Endovascular Surg 2018 Nov 28:1538574418814058. Epub 2018 Nov 28.

1 Division of Transplantation and Vascular surgery, Department of Surgery, Dongsan Medical Center, Keimyung University, Daegu, Korea.

Late occurrence of arterial aneurysms following ligation of a hemodialysis arteriovenous fistula (AVF) is rare. Here, we report the case of 51-year-old male patient with an AVF in which arterial aneurysms developed. The patient had undergone left arm radiocephalic (RC) AVF creation for hemodialysis in 2000. Read More

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November 2018
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Emergency brachial artery ligation for ruptured infected pseudoaneurysm of haemodialysis access is a possible option.

J Vasc Access 2018 Nov 29:1129729818813265. Epub 2018 Nov 29.

Manipal Academy Of Higher Education, Kasturba Medical College, Manipal, Karnataka, India.

Background:: For patients with end-stage renal disease, a good vascular access is essential for chronic haemodialysis. Surgically created access arteriovenous fistula for haemodialysis is associated with multiple complications, and ruptured pseudoaneurysm being the most life threatening and dreaded of all. The management of this complication warrants emergency procedure, although timely diagnosis and arteriovenous fistula salvage has been emphasised. Read More

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November 2018

Vascular Remodeling Process of Heparin-Conjugated Poly(ε-Caprolactone) Scaffold in a Rat Abdominal Aorta Replacement Model.

J Vasc Res 2018 Nov 28;55(6):338-349. Epub 2018 Nov 28.

Department of Vascular Surgery, Xuan Wu Hospital and Institute of Vascular Surgery, Capital Medical University, Beijing,

In the field of vascular graft research, poly-ε-caprolactone (PCL) is used owing to its good mechanical strength and biocompatibility. In this study, PCL scaffold was prepared by electrospinning and surface modification with heparin via hexamethylenediamine. Then the scaffolds were implanted into the infrarenal abdominal aorta of Wistar rats and contrast-enhanced micro-ultrasound was used to monitor the patency of grafts after implantation. Read More

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November 2018

Riskier-than-expected occlusive treatment of ruptured posterior communicating artery aneurysms: treatment and outcome of 620 consecutive patients.

Authors:

J Neurosurg 2018 Oct 1:1-9. Epub 2018 Oct 1.

OBJECTIVEOcclusive treatment of posterior communicating artery (PCoA) aneurysms has been seen as a fairly uncomplicated procedure. The objective here was to determine the radiological and clinical outcome of patients after PCoA aneurysm rupture and treatment and to evaluate the risk factors for impaired outcome.METHODSIn a retrospective clinical follow-up study, data were collected from 620 consecutive patients who had been treated for ruptured PCoA aneurysms at a single center between 1980 and 2014. Read More

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October 2018
1 Read

Rapid cardiac ventricular pacing to facilitate embolization of vein of Galen malformations: technical note.

Authors:

J Neurosurg Pediatr 2018 Oct 1:1-6. Epub 2018 Oct 1.

OBJECTIVEVein of Galen aneurysmal malformations (VGAMs) in infancy have a poor natural history if left untreated. Their high-flow nature can preclude safe and accurate therapeutic vessel occlusion and the risk of inadvertent pulmonary embolism is predominant. The authors describe the technique of rapid cardiac ventricular pacing for inducing transient hypotension to facilitate the controlled embolization of VGAMs. Read More

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October 2018

[Vein of Galen aneurysmal malformation in a Neonate: a case report].

Mali Med 2018 ;33(2):23-25

Centre National Hospitalier Universitaire Hubert Koutoukou Maga de Cotonou, Bénin.

The aneurysm of the Galen vein is a rare and complex congenital intracerabral vascular malformation. We report a case suspected by the obstetric ultrasound in the third trimester and confirmed by the transfontanellar Doppler ultrasound and brain CT-Scan in the asymptomatic 11-day old baby born at term. Read More

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January 2018

Muse Cells and Aortic Aneurysm.

Adv Exp Med Biol 2018 ;1103:273-291

Division of Cardiovascular Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.

The aorta is a well-organized, multilayered structure comprising several cell types, namely, endothelial cells (ECs), vascular smooth muscle cells (VSMCs), and fibroblasts, as well as an extracellular matrix (ECM), which includes elastic and collagen fibers. Aortic aneurysms (AAs) are defined as progressive enlargements of the aorta that carries an incremental risk of rupture as the diameter increases over time. The destruction of the aortic wall tissue is triggered by atherosclerosis, inflammation, and oxidative stress, leading to the activation of matrix metalloproteinases (MMPs), and inflammatory cytokines and chemokines, resulting in the loss of the structural back bone of VSMCs, ECM, and ECs. Read More

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January 2018

A Systematic Review Assessing the Current State of Automated Pupillometry in the NeuroICU.

Neurocrit Care 2018 Nov 27. Epub 2018 Nov 27.

Department of Ophthalmology, Emory University School of Medicine, 1648 Pierce Drive NE, Atlanta, GA, 30307, USA.

The aim of this study was to assess the current state of automated pupillometry technology and its application in the neurointensive care unit (neuroICU). We performed a literature search using the PubMed, MEDLINE, and EMBASE databases from database inception through a search end date of October 18, 2018, to identify studies reporting on the use of automated pupillometry in the care of critically ill patients with neurological impairment. Two independent reviewers reviewed all titles and abstracts in two filtering phases. Read More

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November 2018

A white-bluish plaque with rapid growth after palpation.

Dermatol Pract Concept 2018 Oct 31;8(4):337-339. Epub 2018 Oct 31.

Department of Pathology, Hospital Universitario de Móstoles, Madrid, Spain.

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October 2018

Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells.

Nat Commun 2018 Nov 27;9(1):5022. Epub 2018 Nov 27.

Division of Vascular Surgery, Department of Surgery, New York University Medical Center, New York, NY, 10016, USA.

Abdominal aortic aneurysms (AAA) are characterized by extensive extracellular matrix (ECM) fragmentation and inflammation. However, the mechanisms by which these events are coupled thereby fueling focal vascular damage are undefined. Here we report through single-cell RNA-sequencing of diseased aorta that the neuronal guidance cue netrin-1 can act at the interface of macrophage-driven injury and ECM degradation. Read More

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November 2018
2 Reads

A Large Database Analysis of Rates of Aneurysm Screening, Elective Treatment, and Subarachnoid Hemorrhage in Patients With Polycystic Kidney Disease.

Neurosurgery 2018 Nov 26. Epub 2018 Nov 26.

Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan.

Background: Professional societies provide conflicting guidelines on aneurysm screening in patients with polycystic kidney disease (PKD), and the rate of subarachnoid hemorrhage (SAH) is poorly understood.

Objective: To evaluate screening, elective treatment, and the rate of SAH in patients with known PKD.

Methods: We examined longitudinally linked claims data from a large private insurer, identifying screening, elective treatment, aneurysmal subarachnoid hemorrhage (aSAH) and secured aneurysmal SAH (saSAH) in 2004 to 2014 amongst patients with known PKD. Read More

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November 2018
1 Read

The Prognostic Significance of a Cast Fourth Ventricle in Ruptured Aneurysm Patients With Intraventricular Hemorrhage in the Barrow Ruptured Aneurysm Trial (BRAT).

Neurosurgery 2018 Nov 23. Epub 2018 Nov 23.

Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.

Background: Ruptured aneurysms causing intraventricular hemorrhage (IVH) are associated with high morbidity. The presence of blood that completely fills the fourth ventricle (cast fourth ventricle, CFV) is thought to be particularly ominous, but studies documenting the outcome of such cases are lacking.

Objective: To investigate the outcomes of patients with aneurysmal subarachnoid hemorrhage (aSAH) and CFV. Read More

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November 2018
11 Reads

Combined Microsurgical, Endovascular, and Endoscopic Approach to the Treatment of a Giant Vertebrobasilar Aneurysm.

Oper Neurosurg (Hagerstown) 2018 Nov 24. Epub 2018 Nov 24.

Department of Neurological Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas.

Background: Dolichoectasia is defined as elongation and dilatation of a blood vessel. In the intracranial circulation, the basilar artery is affected in 80% of cases. These are challenging lesions with an aggressive natural history, and treatment carries a relatively high rate of morbidity and mortality. Read More

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November 2018

Massive aneurysmal bone cyst of the skull base treated with denosumab.

Head Neck 2018 Nov 26. Epub 2018 Nov 26.

Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Background: Aneurysmal bone cysts are rare, benign expansile tumors most commonly involving long bones and vertebrae in patients younger than age 20. Skull base involvement is rare. Aneurysmal bone cysts shares radiological and histological features with other bone tumors, posing a diagnostic challenge. Read More

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November 2018
7 Reads

Is there a role for lumbar puncture in early detection of subarachnoid hemorrhage after negative head CT?

Intern Emerg Med 2018 Nov 24. Epub 2018 Nov 24.

Emergency Department, Turku University Hospital, Turku, Finland.

To investigate the role of lumbar puncture (LP) after a negative head computed tomography (CT) when ruling out subarachnoid hemorrhage (SAH) within 24 h of symptom onset. In a single-center, retrospective cohort study, we studied a consecutive series of patients from 2011 to 2015. All patients underwent CT or CT following LP to rule out SAH. Read More

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November 2018
1 Read

Percutaneous albumin/doxycycline injection versus open surgery for aneurysmal bone cysts in the mobile spine.

Eur Spine J 2018 Nov 23. Epub 2018 Nov 23.

Department of Orthopaedics, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing, 100191, China.

Purpose: This study aimed to validate the safety and effectiveness of percutaneous doxycycline/albumin injection for spinal aneurysmal bone cysts (ABCs) as an alternative to open surgery.

Methods: From January 2000 to December 2016, 25 patients who had no/minor neurological deficits (modified Frankel scale D or E) and acceptable local stability (spinal instability neoplastic score < 12) were included in the study, of whom 14 were treated with percutaneous doxycycline/albumin injection (injection group) and 11 were treated with open surgery (surgery group). The demographic and clinical information of the injection and surgery groups were recorded and compared. Read More

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November 2018
1 Read

Reconstructing patient-specific cerebral aneurysm vasculature for in vitro investigations and treatment efficacy assessments.

J Clin Neurosci 2018 Nov 20. Epub 2018 Nov 20.

Department of Mechanical Engineering, University of Washington, Seattle, WA, USA; Department of Neurological Surgery, University of Washington, Seattle, WA, USA.

Perianeurysmal hemodynamics play a vital role in the initiation, growth and rupture of intracranial aneurysms. In vitro investigations of aneurysmal hemodynamics are helpful to visualize and measure blood flow, and aiding surgical planning approaches. Improving in vitro model creation can improve the feasibility and accuracy of hemodynamic investigations and surgical planning, improving clinical value. Read More

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November 2018
1 Read

In Reply to "Demographics of Aneurysmal Subarachnoid Hemorrhage".

World Neurosurg 2018 12;120:593

Department of Global Health and Social Medicine, Harvard Medical School, Global Neurosurgery Initiative, Program in Global Surgery and Social Change, Boston, Massachusetts, USA.

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December 2018
3 Reads

Demographics of Aneurysmal Subarachnoid Hemorrhage.

World Neurosurg 2018 12;120:591-592

Department of Neurosurgery, KAT General Hospital of Attica, Kifisia, Greece.

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December 2018
2 Reads

A Targeting Nanotherapy for Abdominal Aortic Aneurysms.

J Am Coll Cardiol 2018 Nov;72(21):2591-2605

Department of Pharmaceutics, College of Pharmacy, Third Military Medical University, Chongqing, China. Electronic address:

Background: Abdominal aortic aneurysm (AAA) is a leading cause of mortality and morbidity in the elderly. Currently, there remain no effective drugs that can prevent the growth of aneurysms and delay aneurysm rupture in the clinical setting.

Objectives: The aim of this study was to develop a nanotherapy that can target aneurysms and release drug molecules in response to the inflammatory microenvironment. Read More

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November 2018
2 Reads

Detection of Hemodynamic Characteristics Before Growth in Growing Cerebral Aneurysms by Analyzing Time-of-Flight Magnetic Resonance Angiography Images Alone - Preliminary results.

World Neurosurg 2018 Nov 19. Epub 2018 Nov 19.

Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Objective: Cerebral aneurysm growth often precedes rupture. Definite contributors to aneurysm growth have not been determined even by means of recently developed commercially available computational fluid dynamics (CFD) software. We developed an original CFD tool that can analyze data from time-of-flight magnetic resonance angiography (TOF-MRA) prior to growth in the growing aneurysms and investigate possible factors for aneurysm growth in the near future. Read More

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November 2018

All-endoscopic management of benign bone lesions; a case series of 26 cases with minimum of 2 years follow-up.

SICOT J 2018 22;4:50. Epub 2018 Nov 22.

Orthopedics & Trauma Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

Purpose: Assessment of the functional and oncologic outcomes regarding endoscopic curettage of different benign bone tumor types within variable anatomic locations.

Patients And Methods: During the period between February 2012 and December 2016, 26 patients with symptomatic intra-osseous benign bony lesions were included. The age ranged from 3 up to 49 years (mean 20), of 14 females and 12 males. Read More

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November 2018
2 Reads

PERCUTANEOUS TREATMENT OF ANEURYSMAL BONE CYST WITH CALCITONIN AND METHYLPREDNISOLONE.

Acta Ortop Bras 2018 ;26(5):314-319

Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Objective: To introduce the intralesional calcitonin and methylprednisolone percutaneous injection method, which results in the promotion of primary aneurysmal bone cyst (ABC) healing.

Methods: A retrospective cohort study involving 76 patients diagnosed with ABC was performed between 2005 and 2014. Patients treated with calcitonin and methylprednisolone injection and who underwent more than 2 years of follow-up were considered eligible for the study (n=47). Read More

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January 2018

Endovascular Treatment for Vasospasm after Aneurysmal Subarachnoid Hemorrhage Based on Data of JR-NET3.

Neurol Med Chir (Tokyo) 2018 Nov 21. Epub 2018 Nov 21.

Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University.

Endovascular treatments for vasospasm after subarachnoid hemorrhage are typically performed for patients who are refractory to recommended medical therapies. We analyzed the current status of endovascular treatments based on the data of Japanese Registry of Neuroendovascular Therapy (JR-NET)3, and evaluated factors related to improvement of imaging findings and neurological condition, and to mechanical hemorrhage complications. We collected data of 1211 treatments performed from 2010 to 2014. Read More

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November 2018
4 Reads

Optical coherence tomography angiography (OCTA) flow speed mapping technology for retinal diseases.

Expert Rev Med Devices 2018 Nov 21:1-8. Epub 2018 Nov 21.

a Department of Ophthalmology , New England Eye Center, Tufts Medical Center , Boston , MA , USA.

Introduction: Optical coherence tomography angiography (OCTA) is a noninvasive imaging modality for depth-resolved visualization of retinal vasculature. Angiographic data couples with structural data to generate a cube scan, from which en-face images of vasculature can be obtained at various axial positions. OCTA has expanded understanding of retinal vascular disorders and has primarily been used for qualitative analysis. Read More

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November 2018
6 Reads

Endovascular management of endotension by graft reinforcement followed by direct sac embolization.

Minim Invasive Ther Allied Technol 2018 Nov 21:1-7. Epub 2018 Nov 21.

a Department of Radiology , Wakayama Medical University , Wakayamashi , Wakayama , Japan.

Purpose: To assess the efficacy of graft reinforcement followed by percutaneous direct sac embolization (PDSE) for the treatment of endotension after endovascular abdominal aortic aneurysm repair (EVAR).

Materials And Methods: A total of 290 patients underwent elective EVAR. All patients regularly underwent scheduled surveillance with contrast-enhanced computed tomography (CT). Read More

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November 2018