2,721 results match your criteria Aneurysmal Bone Cyst

Percutaneous doxycycline sclerotherapy in a horse with a mandibular aneurysmal bone cyst.

Vet Surg 2022 Jun 22. Epub 2022 Jun 22.

Department of Clinical Sciences, New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania, USA.

Objective: To describe the use and outcome of sclerotherapy with intralesional doxycycline foam in a horse with a mandibular aneurysmal bone cyst.

Study Design: Case report.

Animals: Client-owned 1 year old Standardbred filly. Read More

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Surgical Management of Aneurysmal Bone Cyst of the Pubis: A Case Report and Review of Literature.

Int Med Case Rep J 2022 14;15:287-292. Epub 2022 Jun 14.

Department of Special Surgery, Division of Orthopaedics, School of Medicine, The University of Jordan, Amman, Jordan.

Introduction: Aneurysmal bone cysts (ABC) are expansile, lytic, and benign but locally aggressive lesions. Pelvic ABCs are rare and sometimes difficult to manage surgically.

Case Report: A 17-year-old female presented with progressive pain and swelling in the right inguinal region. Read More

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Bony Cyst in a Ground Glass Matrix: A Rare Case Report of Craniofacial Fibrous Dysplasia with Secondary Aneurysmal Bone Cyst.

Indian J Radiol Imaging 2022 Mar 1;32(1):145-148. Epub 2022 May 1.

Department of Radiodiagnosis and Imaging, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Fibrous dysplasia has various ways of presentation including syndromic associations and secondary changes within the lesion. We present a case of a 21-year-old female with craniofacial fibrous dysplasia, presenting with proptosis and intermittent blurring of vision due to focal fibrous dysplasia involving the frontal bone with secondary aneurysmal bone formation that was provisionally diagnosed on imaging and confirmed on histopathology. This case demonstrates the typical imaging findings of fibrous dysplasia with seldom encountered secondary aneurysmal bone cyst formation and also discusses about the pathology and management of the craniofacial fibrous dysplasia. Read More

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Synchronous polyostotic solid variant of aneurysmal bone cyst involving thoracic vertebrae and harboring a novel AHNAK::USP6 gene fusion. A case report and review.

Virchows Arch 2022 Jun 18. Epub 2022 Jun 18.

Department of Pathology, University of Pittsburgh Medical Center, UPMC Presbyterian Shadyside, Pittsburgh, PA, USA.

Aneurysmal bone cyst (ABC) is a benign bone neoplasm that usually affects the metaphysis of long bones and the posterior elements of vertebral bodies. The rearrangement of USP6 gene is present in most of primary ABC cases. Synchronous polyostotic presentation is extremely rare. Read More

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Approach to Primary Vertebral Tumors in the Light of the 2020 Updated World Health Organization Classification of Bone Tumors.

Turk Neurosurg 2021 Dec 22. Epub 2021 Dec 22.

Umraniye Education and Research Hospital, Department of Pathology, Istanbul, Turkey.

Aim: The spinal canal frequently harbors primary and secondary bone tumors. These tumors have specific localization, age range, and clinical and radiological manifestations, and their treatment requires a multidisciplinary approach. In most cases, a definitive diagnosis is made based on clinical, radiological, and histopathological findings. Read More

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December 2021

Reconstruction of the Fourth Metacarpal Using a Chimeric Medial Femoral Condyle Vascularized Osteochondral Cutaneous Graft: Case Report.

Ann Plast Surg 2022 May 30. Epub 2022 May 30.

Plastic Surgery Office CenterPlast, Saarbrücken, Germany.

Background: The medial femoral condyle has become a matter of great interest, thanks to the possibility of harvesting versatile chimeric flaps for reconstruction of metacarpal defects with minimal donor site morbidity. This case stands out because of the complete reconstruction of the metacarpal head, harvesting with a skin paddle for tension-free closure and monitoring, and the use of external fixation for better predictability of the reconstruction and early postoperative mobilization.

Case Presentation: We report the case of a 20-year-old male patient who presented with an aneurysmal bone cyst involving the fourth metacarpal bone. Read More

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Aneurysmal bone cyst secondary to giant cell tumor of the extremities: a case series of 30 patients.

Am J Transl Res 2022 15;14(5):3198-3206. Epub 2022 May 15.

Department of Orthopedics, The First Affiliated Hospital of Guangxi Medical University Nanning, Guangxi, China.

The purpose was to investigate the clinical features, diagnosis, treatment, and prognosis of aneurysmal bone cyst (ABC) secondary to giant cell tumors (GCT) of the extremities. Data from patients with ABC secondary to GCT of the extremities were obtained from the medical records. Clinical features, imaging findings, pathologic diagnosis, surgical methods, and prognosis were analyzed. Read More

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Intracranial extraosseous dural-based Ewing's sarcoma with fluid-haematocrit levels: imaging findings of a rare tumour.

BMJ Case Rep 2022 Jun 14;15(6). Epub 2022 Jun 14.

Radiodiagnosis, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India.

Extraosseous dural-based primary Ewing's sarcoma of the central nervous system is a rare tumour posing a diagnostic challenge. On cross-sectional radiological imaging, the lesion has an extra-axial location with heterogeneous appearance. These lesions are usually multicystic with internal haemorrhage causing fluid-haematocrit levels. Read More

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Total en bloc spondylectomy of thoracic giant cell tumor with secondary aneurysmal bone cyst: case reports and review of literature.

Int J Neurosci 2022 Jun 13:1-6. Epub 2022 Jun 13.

Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Spinal giant cell tumor (GCT) combined with secondary aneurysmal bone cyst (ABC) is a locally aggressive primary bone tumor. Total en bloc spondylectomy has never been reported to treat thoracic GCT combined with secondary ABC. We retrospectively reviewed two cases of spinal GCT combined with secondary ABC. Read More

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[Aneurysmal bone cyst of mandible: report of a case].

J W Ao Q R Chen

Zhonghua Bing Li Xue Za Zhi 2022 Jun;51(6):564-566

Department of Pathology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.

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Fibrous Dysplasia With Aneurysmal Bone Cyst Presenting as Sinonasal Mass.

Cureus 2022 Apr 25;14(4):e24485. Epub 2022 Apr 25.

Department of Radiodiagnosis, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.

Craniofacial involvement in fibrous dysplasia is a rare occurrence and complications of it are even rarer. Involvement of the sinonasal region can pose a challenge in both diagnosis and management. We hereby present a case of craniofacial fibrous dysplasia complicated with secondary aneurysmal bone cyst formation in a 15-year-old male patient. Read More

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GRM1 Immunohistochemistry Distinguishes Chondromyxoid Fibroma From its Histologic Mimics.

Am J Surg Pathol 2022 Jun 1. Epub 2022 Jun 1.

Department of Pathology, Stanford University School of Medicine, Stanford, CA.

Chondromyxoid fibroma (CMF) is a rare benign bone neoplasm that manifests histologically as a lobular proliferation of stellate to spindle-shaped cells in a myxoid background, exhibiting morphologic overlap with other cartilaginous and myxoid tumors of bone. CMF is characterized by recurrent genetic rearrangements that place the glutamate receptor gene GRM1 under the regulatory control of a constitutively active promoter, leading to increased gene expression. Here, we explore the diagnostic utility of GRM1 immunohistochemistry as a surrogate marker for GRM1 rearrangement using a commercially available monoclonal antibody in a study of 230 tumors, including 30 CMF cases represented by 35 specimens. Read More

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Clinicoradiological outcome of percutaneous intralesional polidocanol in Aneurysmal Bone Cysts: A prospective study of 43 patients in a single tertiary care centre.

J Orthop 2022 Jul-Aug;32:72-77. Epub 2022 May 19.

Department of Orthopaedics Seth GS Medical College and KEM Hospital, Mumbai, India.

Objective: The study reports the efficacy of sequential instillations of intralesional percutaneous polidocanol in the treatment of skeletal ABC. The study also analyses the pain relief, recurrence, radiological outcome and complications after percutaneous sclerotherapy.

Materials And Methods: A total of 43 patients with ABC were managed by fluoroscopy assisted percutaneous intralesional sclerotherapy with 3% Injection Polidocanol under suitable anaesthesia. Read More

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Oestrogen receptor expression distinguishes non-ossifying fibroma from other giant cell containing bone tumours.

Virchows Arch 2022 May 25. Epub 2022 May 25.

Department of Pathology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

Non-ossifying fibroma (NOF) and central giant cell granuloma (CGCG) are both benign tumours of bone with overlapping morphology and similar mutations in the RAS/MAPK pathway. However, NOF is located in the long bones with regression after puberty in contrast to CGCG which is located in the jaw bones and does not regress spontaneously. We hypothesised that endocrine regulation by oestrogen plays a role in the spontaneous regression in NOF. Read More

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Aneurysmal bone cyst of the proximal femur concomitant with Graves' disease and Moyamoya disease: report of a rare case.

J Int Med Res 2022 May;50(5):3000605221097669

Department of Joint Surgery, The Third People's Hospital of Shenzhen, Shenzhen, Guangdong Province, China.

Aneurysmal bone cyst is a type of benign bone pathology with expansile and osteolytic features whose etiology remains unclear. Graves' disease is an autoimmune disease characterized by diffuse goiter and hyperthyroidism. Moyamoya disease is a progressive cerebral vasculopathy. Read More

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Primary Benign Tumors of the Spinal Canal.

World Neurosurg 2022 May 10;164:178-198. Epub 2022 May 10.

Subdirection of basic research, Instituto Nacional de Cancerología, México City, Mexico. Electronic address:

Benign tumors that grow in the spinal canal are heterogeneous neoplasms with low incidence; from these, meningiomas and nerve sheath tumors (neurofibromas and schwannomas) account for 60%-70% of all primary spinal tumors. Benign spinal canal tumors provoke nonspecific clinical manifestations, mostly related to the affected level of the spinal cord. These tumors present a challenge for the patient and healthcare professionals, for they are often difficult to diagnose and the high frequency of posttreatment complications. Read More

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[Giant-cell tumor of bone in 2022].

Ann Pathol 2022 Apr 3;42(3):214-226. Epub 2022 May 3.

Service de pathologie, hôpital Trousseau, CHRU de Tours, Tours, France; Université de Tours, Tours, France.

Giant cell tumors of bone (GCTs) are rare mesenchymal tumors classified as intermediate in the WHO 2020 classification, i.e. neither completely benign nor definitely malignant, due to recurrence (frequent) and pulmonary metastases (rare). Read More

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Clinicoradiological spectrum of primary aneurysmal bone cysts of the maxillofacial region: A series of 31 cases.

Dentomaxillofac Radiol 2022 Jul 23;51(5):20220071. Epub 2022 May 23.

Department of Oral Pathology and Oral Biology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.

Objectives: The aim of the current study was to analyse the demographic, clinical and radiological features of primary aneurysmal bone cysts (ABCs) involving the maxillofacial region.

Methods: Histologically confirmed cases affecting the maxillofacial region were retrospectively reviewed over a 21-year period (2000-2021). Cases were collected from the archives of five Oral Pathology laboratories from three countries: South Africa, Guatemala and Brazil. Read More

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Epigenetic lockdown of CDKN1A (p21) and CDKN2A (p16) characterises the neoplastic spindle cell component of giant cell tumours of bone.

J Pathol 2022 May 6. Epub 2022 May 6.

Institute of Pathology, University Hospital Ulm, Ulm, Germany.

Giant cell tumour of bone (GCTB) comprises the eponymous osteoclastic multinucleated giant cells eliciting bone lysis, an H3F3A-mutated neoplastic mononucleated fibroblast-like cell population, and H3F3A wild-type mononucleated stromal cells. In this study, we characterised four new cell lines from GCTB. Furthermore, we compared the genome-wide DNA methylation profile of 13 such tumours and three further cell lines with giant cell-rich lesions comprising three H3F3B-mutated chondroblastomas, three USP6-rearranged aneurysmal bone cysts, three non-ossifying fibromas, two hyperparathyroidism-associated brown tumours as well as mesenchymal stem cells, osteoblasts, and osteoclasts. Read More

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A 5-Year-Old Female With an Aneurysmal Bone Cyst of the Proximal Humerus.

Cureus 2022 Apr 2;14(4):e23761. Epub 2022 Apr 2.

Surgery, Lala Lajpat Rai (LLR) Hospital, Kanpur, IND.

An aneurysmal bone cyst (ABC) is a non-malignant, skeletal tumor that is extremely rare and most commonly presents within the first two decades of life. Genetic mutation of the gene on chromosome 17 remains to be the most commonly accepted reasoning as ABC's etiology remains unknown. As the radiographic appearance of ABC is quite similar to other kinds of bone cysts, a histological diagnosis is often required to attain a definitive diagnosis. Read More

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Aneurysmal bone cyst of the pelvis and sacrum: a single-center study of 17 cases.

BMC Musculoskelet Disord 2022 Apr 30;23(1):405. Epub 2022 Apr 30.

Department of General Paediatrics, University Children's Hospital Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.

Background: The aneurysmal bone cyst (ABC) is a benign, but locally aggressive cystic lesion of the bone. It usually occurs in the metaphysis of long bones of adolescents and young adults but can also affect the pelvis.

Methods: This single-center study is a retrospective review of 17 patients with primary ABCs of the pelvis. Read More

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Treatment of locally aggressive benign bone tumors by means of extended intralesional curettage without chemical adjuvants.

SAGE Open Med 2022 22;10:20503121221094199. Epub 2022 Apr 22.

Department of Orthopedics and Traumatology, Marmara University Pendik Training and Research Hospital, İstanbul, Turkey.

Objectives: The aim of this study is to present the clinical, oncological, and functional results of locally aggressive benign bone tumors treated with extended intralesional curettage without the use of adjuvant in a tertiary orthopedic oncology center.

Method: A total of 172 patients treated with surgical curettage and high-speed burrs for the diagnosis of aneurysmal bone cyst, giant cell tumor, osteoblastoma, chondroblastoma, and chondromyxoid fibroma were included in the study. Demographic, radiological, and clinical data of the patients were analyzed. Read More

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A sizeable aneurysmal bone cyst of the mandibular ramus on 15-year-old patient. Intraoral approach.

J Stomatol Oral Maxillofac Surg 2022 Apr 25. Epub 2022 Apr 25.

Otorhinolaryngology - Oral and Maxillofacial Surgery Department, Metropolitan General Hospital, 264 Mesogeion Av., P.C. 15562, Athens, Greece. Electronic address:

Aneurysmal bone cysts (ABCs) are benign, non-neoplastic bone lesions, which contain blood and demonstrate a destructive pattern. They rarely occur in the head and neck region, with the mandible being the most common site of craniofacial origin. They develop in the second decade of life and their etiology is obscure. Read More

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[Giant cell-containing tumors of bone and differential diagnoses].

Pathologe 2022 May 25;43(3):174-182. Epub 2022 Apr 25.

Gerhard-Domagk-Institut für Pathologie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Deutschland.

Osteoclastic giant cells represent a common cellular component of lesions arising in bone. Highlighting this morphological finding, the current WHO classification of bone tumors defines a diagnostic group comprising aneurysmal bone cyst, giant cell tumor of bone and non-ossifying fibroma, which may display morphologic similarities while being distinct with regard to molecular and biological features. Starting with these tumors - putting a focus on lesions arising in bone - this article gives a survey of other (chondrogenic and osteogenic) tumors that frequently contain osteoclastic giant cells, which may, particularly in small biopsies, enter differential diagnosis. Read More

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Soft tissue aneurysmal bone cyst of left hemithorax: An extremely rare case.

Indian J Pathol Microbiol 2022 Apr-Jun;65(2):452-454

Department of Surgical Oncology, The Gujarat Cancer and Research Institute, New Civil Hospital Campus, Asarwa, Ahmedabad, Gujarat, India.

Aneurysmal bone cyst (ABC) is a benign expansile cystic lesion that can affect any bone of the skeleton, especially the femur, tibia, and humerus. Lesions with histologic features of an ABC can be originated within soft tissue in exceedingly rare cases. Extra-skeletal ABC may mimic a variety of benign and malignant lesions and can be confused with other common or rare giant cell-rich tumors of soft tissue. Read More

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Primary Aneurysmal Bone Cyst of Nasal Cavity and Sinuses in a Child: Case Report and Literature Review.

Ear Nose Throat J 2022 Apr 15:1455613221081569. Epub 2022 Apr 15.

Department of Otolaryngology, Head and Neck Surgery, 117984Beijing Children's Hospital, Capital Medical University, China.

Introduction: Aneurysmal bone cysts (ABCs) are a rare benign bone lesion, which are divided into primary and secondary categories, and occur mainly in the vertebra and the long tubular bones. Primary ABCs in the nasal cavity and the sinuses are rare.

Case Presentation: We reported on a one-year-old boy who suffered from progressive nasal obstruction and intermittent nosebleeds over a period of approximately 1 month. Read More

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FDG PET/CT Image of Soft Tissue Aneurysmal Bone Cyst.

Clin Nucl Med 2022 Apr 15. Epub 2022 Apr 15.

From the Department of Nuclear Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China.

Abstract: Soft tissue aneurysmal bone cyst is very rare. Herein, we report FDG PET/CT findings of aneurysmal bone cyst in a 19-year-old man. On conventional image, it presented as a paravertebral soft tissue mass with heterogeneous enhancement and rim eggshell-like calcification. Read More

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Giant Cell Tumor of Intermediate Cuneiform Evolving into Aneurysmal Bone Cyst: A Rare Case Report.

J Orthop Case Rep 2021 Sep;11(9):12-15

Department of Orthopaedics, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.

Introduction: Giant cell tumor (GCT) most commonly involves distal femoral condyles, distal end of radius, proximal tibial plateau, and proximal humerus. GCT is uncommon to occur in small bones of hand and feet. 2% of GCT occur in hand. Read More

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September 2021

Unilateral Biportal Endoscopic Tumor Removal and Percutaneous Stabilization for Extradural Tumors: Technical Case Report and Literature Review.

Front Surg 2022 24;9:863931. Epub 2022 Mar 24.

Joint and Arthritis Research, Orthopedic Surgery, Himchan Hospital, Seoul, South Korea.

Background: Extradural spinal tumors arise from soft or bony tissues in the spine and account for majority of spinal tumors. Interest in the unilateral biportal endoscopic (UBE) technique is rising, because it can easily decompress the bony spinal canal and accommodate all open surgical instruments under endoscopic guidance. However, reports of this technique have been limited to certain diseases. Read More

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Aneurysmal bone cyst of the spine in adult patients: A systematic review and comparison of primary vs secondary lesions.

J Clin Neurosci 2022 Jun 1;100:15-22. Epub 2022 Apr 1.

Texas A&M University College of Medicine, Houston, TX, USA; Department of Neurosurgery, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Background: Spine aneurysmal bone cysts (ABCs) rarely occur in adults. Primary and secondary lesions may show some differences and require appropriate treatments.

Objective: To systematically review the literature on adult spine ABCs. Read More

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