2,601 results match your criteria Aneurysmal Bone Cyst

Medial malleolar osteotomy for intralesional curettage and bone grafting of primary aneurysmal bone cyst of the talus.

BMJ Case Rep 2021 May 7;14(5). Epub 2021 May 7.

Orthopaedics, AIIMS, Bhubaneswar, Orissa, India.

Access to the cystic lesion of the talar body without damage to the articular surface is difficult. This case report is about a 23-year-old man who had a symptomatic huge cystic lesion in the left-sided talus bone. Radiograph and CT scan showed an expansile lytic lesion within the talar body. Read More

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Primary aneurysmal bone cyst of the calcaneum: A report of three cases and review of literature.

Foot (Edinb) 2021 Mar 2;47:101795. Epub 2021 Mar 2.

Department of Pathology, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India. Electronic address:

Case Description: Aneurysmal bone cysts (ABCs) are locally aggressive, cystic lesions of the skeletal system, most commonly seen in the metaphyseal region of long bones. On the other hand, an ABC of the foot (especially the calcaneum) is a rare entity, with very few cases reported in the literature. In this study, we present three such cases who presented to us with the chief complaint of chronic heel pain. Read More

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Imaging of Non-ossifying Fibromas: A Case Series.

Cureus 2021 Mar 25;13(3):e14102. Epub 2021 Mar 25.

Trauma and Orthopaedics, Addenbrooke's Hospital, Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, GBR.

Non-ossifying fibromas (NOFs) are common lesions most frequently found in the growing bones of children and adolescents. Although NOFs are benign, their presence as incidental findings often triggers further investigation as they are sometimes mistaken for more sinister bone lesions such as aneurysmal bone cysts. NOFs can also pose an increased risk of pathological fractures. Read More

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Efficacy of Sclerotherapy With Polidocanol (Ethoxysclerol) in Primary Aneurysmal Bone Cysts in Children and Adolescents.

J Pediatr Orthop 2021 Apr 23. Epub 2021 Apr 23.

Departments of Orthopaedic Surgery Interventional Radiology, Leiden University Medical Centre, Leiden, The Netherlands.

Background: Aneurysmal bone cysts (ABC) are rare benign osseous lesions that can be locally aggressive. Traditionally, curettage with or without bone grafting is the treatment of choice. Recent data suggest that percutaneous sclerotherapy is a safe alternative to surgery. Read More

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Clinicopathological and Prognostic Characteristics in Spinal Chondroblastomas: A Pooled Analysis of Individual Patient Data From a Single Institute and 27 Studies.

Global Spine J 2021 Apr 26:21925682211005732. Epub 2021 Apr 26.

Department of Spine Surgery, The First Affiliated Hospital, University of South China, Hengyang, China.

Study Design: Retrospective pooled analysis of individual patient data.

Objectives: Spinal chondroblastoma (CB) is a very rare pathology and its clinicopathological and prognostic features remain unclear. Here, we sought to characterize the clinicopathological data of a large spinal CB cohort and determine factors affecting the local recurrence-free survival (LRFS) and overall survival (OS) of patients. Read More

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Chondroblastoma of the patella with secondary aneurysmal bone cyst, an easily misdiagnosed bone tumor:a case report with literature review.

BMC Musculoskelet Disord 2021 Apr 23;22(1):381. Epub 2021 Apr 23.

Ningxia Medical University, 1160 Shengli Street, Xingqing District, Yinchuan, 750004, People's Republic of China.

Background: Chondroblastoma (CB) is a rare, primary, benign bone tumor that commonly affects men aged 15-20 years. It is usually detected in the epiphysis of the long bones, such as the proximal femur, humerus, and tibia. The patella is an infrequent site. Read More

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Quantitative bone SPECT/CT applications for primary bone neoplasms.

Hell J Nucl Med 2021 Jan-Apr;24(1):36-44. Epub 2021 Apr 20.

Department of Radiology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501 Japan.

Objective: To evaluate the clinical utility of quantitative values obtained with bone single photon emission computed tomography/computed tomography (SPECT/CT) for primary bone neoplasms.

Subjects And Methods: Bone SPECT/CT scans of 23 patients with 19 benign bone neoplasms (5 osteoid osteomas, 4 bone giant cell tumor, 4 osteofibrous dysplasia, 3 intraosseous ganglion, 2 aneurysmal bone cyst, 1 intraosseous hemangioma) and 5 malignant bone neoplasms (2 osteosarcoma, 1 periosteal osteosarcoma, 1 malignancy in bone giant cell tumor, 1 Ewing sarcoma) were retrospectively analyzed with maximum standardized uptake value (SUVmax), peak SUV (SUVpeak), mean SUV (SUVmean), metabolic bone volume (MBV), and total bone uptake (TBU) of primary lesions.

Results: Mean SUVmax of 19 benign and 5 malignant primary bone neoplasms were 6. Read More

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Towards better understanding of giant cell granulomas of the oral cavity.

J Clin Pathol 2021 Apr 15. Epub 2021 Apr 15.

Oral Pathology, University of Missouri Kansas City, Kansas City, Missouri, USA.

Giant cell granulomas are enigmatic lesions of the oral cavity characterised by a peculiar combined proliferation of mononuclear and multinucleated giant cells in a mesenchymal stromal background. Central and peripheral giant cell granulomas may have similar pathogenesis and histology but differ in their location and biological behaviour. It is important to differentiate them from other giant cell lesions that can occur in the oral cavity, such as giant cell tumour of the bone, aneurysmal bone cyst, brown tumour of hyperparathyroidism, and giant cell lesions of Ramon syndrome, Noonan syndrome, neurofibromatosis and Jaffe-Campanacci syndrome. Read More

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Selective arterial embolization of aneurysmal bone cyst in the pubic bone: A possible primary treatment.

Radiol Case Rep 2021 Jun 28;16(6):1280-1283. Epub 2021 Mar 28.

Department of Medical Imaging, Division of Vascular and Interventional Radiology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

Aneurysmal bone cyst is a benign highly vascular lesion that occurs in children. Traditionally ABCs were treated by surgical resection. However, lesions at difficult to access anatomical locations such as the pelvis have higher morbidity when treated surgically. Read More

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Impact of Secondary Aneurysmal Bone Cysts on Survival of Patients with Enneking Stage IIB Extremity Osteosarcoma: A Propensity Score Matching Analysis.

Ann Surg Oncol 2021 Apr 2. Epub 2021 Apr 2.

Department of Oncology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

Background: The clinicopathology of aneurysmal bone cysts (ABCs) secondary to osteosarcoma has not yet been reported. We conduct a retrospective review of ABCs secondary to osteosarcoma to characterize clinicopathology and influence on the survival of patients with Enneking stage IIB extremity osteosarcoma.

Patients And Methods: A total of 300 patients with Enneking stage IIB extremity osteosarcoma were eligible for analysis. Read More

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Open Curettage With Bone Augmentation for Symptomatic Tumors and Tumor-like Lesions of Calcaneus: A Comparison of Bioactive Glass Versus Allogeneic Bone.

J Foot Ankle Surg 2021 Mar 9. Epub 2021 Mar 9.

Chief Physician, Department of Orthopaedics, the First Hospital of China Medical University, Shenyang, Liaoning, China. Electronic address:

Few studies have characterized the clinical outcomes of 45S5 Bioglass® applied as a bone graft to that of allogeneic bone applied in calcaneal open curettage. Therefore, the purpose of the present investigation was to compare the outcomes of patients with calcaneal tumors and tumor-like lesions treated by open curettage with 45S5 Bioglass® or allogeneic bone. Of the 31 patients who underwent open curettage (18 cases of unicameral bone cysts, 7 cases of aneurysmal bone cysts, and 6 cases of intraosseous lipoma), 16 (52%) received grafts with 45S5 Bioglass® and 15 (48%) with allogeneic bone. Read More

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Aneurysmal bone cyst of the foot: A series of 10 cases.

Foot Ankle Surg 2021 Mar 6. Epub 2021 Mar 6.

Department of Orthopedics and Tumororthopedics, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149 Muenster, Germany. Electronic address:

Background: Aneurysmal bone cyst (ABC) is a benign, locally aggressive tumor that occurs in childhood and early adulthood. It usually affects the metaphysis of long bones but can also occur in the foot.

Methods: This single-center study is a retrospective review of ten patients with primary ABCs of the foot which underwent an intralesional curettage or a polidocanol instillation. Read More

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Severe Acute Lung Injury After H2O2 Irrigation of an Aneurysmal Bone Cyst in an 8-Year-Old Girl: A Case Report.

A A Pract 2021 Mar 15;15(3):e01424. Epub 2021 Mar 15.

From the Division of Pediatric Intensive Care and Pulmonology.

An 8-year-old girl developed severe acute lung injury after irrigation of a pelvic aneurysmal bone cyst with H2O2 and filling with bone cement. Sudden profound oxygen desaturation occurred on the operating table when the patient was turned from the prone to the supine position. After a brief improvement in her oxygenation, the girl developed rapidly progressing severe respiratory failure necessitating reintubation and hour-long manual ventilation, while copious amounts of hemorrhagic frothy fluids were aspirated through the endotracheal tube. Read More

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Liquid Absolute Alcohol Based Sclerotherapy - A Boon in Large Grade 3 Aneurysmal Bone Cyst of Proximal Humerus in a Child.

Sharat Agarwal

J Orthop Case Rep 2020 Nov;10(8):23-26

Department of Orthopaedics, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India.

Introduction: Aneurysmal bone cyst (ABC) is a benign intraosseous lesion, usually seen before the age of 20 years and is a lesion filled with blood cavities causing a blowout distension of the bone. It constitutes to about 1% of benign bone tumors. Although benign, a large lesion is liable to develop pathological fracture, so needs prompt addressal. Read More

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November 2020

Aneurysmal Bone Cyst of the Medial Cuneiform: A Case Report.

J Am Podiatr Med Assoc 2021 Feb;111(1)

The aneurysmal bone cysts, usually found in the tibia, femur, pelvis, or humerus, are expansile pseudotumor lesions of unknown etiology. An aneurysmal bone cyst is rarely seen in the medial cuneiform. In this case report, a 43-year-old man with an aneurysmal bone cyst in the left medial cuneiform is presented. Read More

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February 2021

Percutaneous Microwave Ablation and Osteoplasty of an Aneurysmal Bone Cyst.

J Vasc Interv Radiol 2021 Mar 6. Epub 2021 Mar 6.

Second Department of Radiology, School of Medicine, National and Kapodistrian University of Athens, 'Attikon' University General Hospital, Athens, Greece.

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Surgical Strategy of Pediatric Benign Sacral Tumors.

J Pediatr Orthop 2021 Apr;41(4):227-235

Musculoskeletal Tumor Center, Peking University People's Hospital, Beijing, China.

Background: Primary benign osseous tumors and tumor-like lesions at the sacrum are rare in the pediatric population and exact surgical strategy is still unclear. In this study, we evaluate the outcome for pediatric patients with benign tumors and tumor-like lesions at the sacrum who were receiving surgical treatment according to our proposed surgical strategy and classification.

Methods: We analyzed 49 pediatric patients with sacral benign tumors or tumor-like lesions aged 18 years and below from 2005 to 2018. Read More

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Differential diagnosis of T2 hypointense masses in musculoskeletal MRI.

Skeletal Radiol 2021 Mar 2. Epub 2021 Mar 2.

Department of Radiology, University of Miami Miller School of Medicine/Jackson Memorial Hospital, 1611 NW 12th Ave, JMH WW 279, Miami, FL, 33136, USA.

Many soft tissue masses have an indeterminate appearance on MRI, often displaying varying degrees and extent of T2 hyperintensity. However, a subset of neoplasms and tumor-like lesions may exhibit prominent areas of T2 hypointensity relative to skeletal muscle. The hypointensity observed on T2-weighted MRI can be caused by a variety of substances, including evolving blood products, calcifications or other inorganic crystals, or fibrous tissue. Read More

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Aneurysmal Bone Cysts of the Paranasal Sinuses: The Mayo Clinic Experience and Review of the Literature.

Laryngoscope 2021 Mar 1. Epub 2021 Mar 1.

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, U.S.A.

Objective/hypothesis: Aneurysmal bone cysts (ABCs) are benign, lytic bone lesions, which rarely present in the paranasal sinuses. There is no published consensus on the appropriate diagnostic or treatment approach. Our objective was to elucidate the clinical behavior, treatment, and outcomes for patients with ABCs of the paranasal sinuses (psABCs). Read More

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En Bloc Resection for a Malignant Spine Tumor After Balloon Kyphoplasty: Histological Findings of a Retrieved Vertebral Body: A Case Report.

JBJS Case Connect 2021 02 23;11(1). Epub 2021 Feb 23.

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Case: A 45-year-old woman with severe back pain underwent percutaneous curettage and balloon kyphoplasty (BKP) of a lesion believed to be aneurysmal bone cyst. Three months after BKP, local recurrence was observed, and the histological diagnosis was revised to malignant tumor. Thus, we performed a total en bloc spondylectomy, and the L3 vertebral body was resected. Read More

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February 2021

Efficacy of treatment interventions for primary aneurysmal bone cysts: a systematic review.

Bone Jt Open 2021 Feb;2(2):125-133

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Aims: Aneurysmal bone cysts (ABCs) are locally aggressive lesions typically found in the long bones of children and adolescents. A variety of management strategies have been reported to be effective in the treatment of these lesions. The purpose of this review was to assess the effectiveness of current strategies for the management of primary ABCs of the long bones. Read More

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February 2021

Denosumab Treatment for Giant Cell Tumors, Aneurysmal Bone Cysts, and Fibrous Dysplasia-Risks and Benefits.

Curr Osteoporos Rep 2021 Apr 22;19(2):141-150. Epub 2021 Feb 22.

Skeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Building 30 Room 228 MSC 4320, Bethesda, MD, 20892, USA.

Purpose Of Review: This review summarizes current understanding of the role of denosumab, an inhibitor of receptor activator of nuclear kappa-B ligand (RANKL), in the management of 3 skeletal neoplasms: giant cell tumors, aneurysmal bone cysts, and fibrous dysplasia.

Recent Findings: A growing body of literature supports denosumab use in giant cell tumors, a neoplasm in which RANKL plays a clear pathogenic role. Comparatively less data is available in aneurysmal bone cysts and fibrous dysplasia; however, the pathogenic similarity of these disorders to giant cell tumors, as well as encouraging preliminary data, suggests denosumab may be useful. Read More

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Atypical Presentation of Navicular Aneurysmal Bone Cyst in a Symptomatic Pediatric Flatfoot Deformity: A Case Report.

J Foot Ankle Surg 2021 May-Jun;60(3):609-614. Epub 2020 Sep 8.

Resident, Wake Forest Baptist Medical Center, Winston-Salem, NC.

Aneurysmal bone cysts (ABCs) are rare in the foot, accounting for 4% to 6.3% of all ABCs found in the body. Approximately 80% of patients diagnosed with an ABC are in the second decade of life. Read More

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September 2020

Ubiquitin-specific Peptidase 6 ()-associated Fibroblastic/Myofibroblastic Tumors: Evolving Concepts.

Cancer Genomics Proteomics 2021 Mar-Apr;18(2):93-101

Department of Orthopaedic Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.

Ubiquitin-specific peptidase 6 (USP6) is a hominoid-specific gene residing on chromosome 17p13 and serves as a deubiquitinating enzyme with a diverse set of functions including intracellular trafficking, inflammatory signaling, cell transformation and protein turnover. USP6 rearrangements were first identified in aneurysmal bone cysts, resulting in promoter swapping and over-expression of wild type USP6. Several morphologically overlapping fibroblastic/myofibroblastic tumors are known to harbor USP6 rearrangements, including nodular fasciitis, cellular fibroma of tendon sheath, myositis ossificans and fibro-osseous pseudotumor of digits. Read More

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January 2021

A Destructive Tumor of the Proximal Tibia and Fibula: A Case Report Highlighting Challenging Diagnosis and Treatment of a Locally Advanced, Non-recurrent Chondroblastoma in 16 Years Old Patient.

J Orthop Case Rep 2020 Oct;10(7):63-67

Department of Orthopaedic Surgery, Allegheny General Hospital, Pittsburgh, Pennsylvania, United States.

Introduction: Chondroblastoma is a rare, cartilaginous primary bone tumor, which presents predominantly in children and young adults. These tumors represent 1% of all primary bone tumors. Patients tend to complain of progressive joint pain which usually aids in early diagnosis. Read More

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October 2020

Novel partners of USP6 gene in a spectrum of bone and soft tissue lesions.

Virchows Arch 2021 Feb 9. Epub 2021 Feb 9.

Service d'anatomie et cytologie pathologiques, CHRU de Tours, Avenue de la République, 37044 Cedex 9, Tours, France.

Nodular fasciitis, primary aneurysmal bone cyst, myositis ossificans, and their related lesions are benign tumors that share common histological features and a chromosomal rearrangement involving the ubiquitin-specific peptidase 6 (USP6) gene. The identification of an increasing number of new partners implicated in USP6 rearrangements demonstrates a complex tumorogenesis of this tumor spectrum. In this study on a series of 77 tumors (28 nodular fasciitis, 42 aneurysmal bone cysts, and 7 myositis ossificans) from the database of the French Sarcoma Group, we describe 7 new partners of the USP6 gene. Read More

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February 2021

Percutaneous treatments of primary aneurysmal bone cysts: systematic review and meta-analysis.

Eur J Orthop Surg Traumatol 2021 Feb 7. Epub 2021 Feb 7.

Department of Periodontology, Universidade Federal de Pelotas, Rio Grande Do Sul, Rua Gonçalves Chaves, 457, Pelotas, CEP: 96015-560, Brazil.

Purpose: To systematically review the literature to determine recurrence rates of percutaneous treatments for primary aneurysmal bone cysts (ABC).

Methods: Search strategies were performed in the following databases: PubMed, SCIELO, LILACS and BVS, using terms in English, Spanish and Portuguese (PROSPERO Registration Number: CRD42020170340). Longitudinal studies, either observational or clinical trials, with at least five patients and with a mean of 18 months of follow-up were included. Read More

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February 2021

Soft tissue aneurysmal bone cyst of left hemithorax with review of literature.

Indian J Thorac Cardiovasc Surg 2021 Jan 28:1-4. Epub 2021 Jan 28.

The Gujarat Cancer & Research Institute, Ahmedabad, Gujarat India.

Soft tissue aneurysmal bone cysts (STABCs) are extremely rare extraosseous counterpart of aneurysmal bone cyst (ABC), with close resemblance to histo-morphologic characteristics of ABC. Here we would like to report a 13-year-old female patient, who presented with a large mass, occupying the entire left hemithorax. Patient underwent resection of the thoracic mass. Read More

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January 2021

Efficacy of Lesion Specific Portals in Endoscopic Treatment of Calcaneal Bone Cyst: A Case Report and Literature Review.

Medicina (Kaunas) 2021 Jan 26;57(2). Epub 2021 Jan 26.

Department of Orthopaedic Surgery, Soonchunhyang University Seoul Hospital, 59, Daesagwan-ro, Yongsan-gu, Seoul 04401, Korea.

Calcaneal bone cysts rarely occur and most of them are known to be benign. Among them, simple bone cysts (SBCs) third most commonly occur in the calcaneus and of the many surgical treatment options, endoscopic curettage is recently gaining popularity among surgeons due to its advantages of minimal invasiveness and optimal visualization. As for portal placement for endoscopy, two lateral portals are considered a standard technique, but no rationale has been established for SBCs with abnormal geometry. Read More

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January 2021

Aneurysmal bone cyst of the head & neck: A review of reported cases in the literature.

J Stomatol Oral Maxillofac Surg 2021 Jan 30. Epub 2021 Jan 30.

Division of Oral & Maxillofacial Pathology, NewYork-Presbyterian/Columbia University Irving Medical Center, New York, NY 10032, United States. Electronic address:

The aneurysmal bone cyst (ABC) is a benign, blood-filled bony lesion that notoriously affects the vertebral column and long bones of the body. Rarely, ABCs can manifest in the head and neck (HNABC). The purpose of this paper is to provide a comprehensive review of existing literature on HNABC. Read More

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January 2021