Search Our Scientific Publications & Authors

Angiol Sosud Khir 2019 ;25(1):169-174

Department of Aorta and Coronary Arteries Surgery, National Medical Research Centre named after Academician E.N. Meshalkin under the RF Ministry of Public Health, Novosibirsk, Russia.

Presented herein is the remote (more than 15-year follow up) result of successful surgical treatment of aortic coarctation complicated by septic aortitis and a false aneurysm of the anastomosis between the graft and the aortic arch. In 2002, after correction of aortic coarctation the woman was admitted to our Clinic with an incompetent proximal anastomosis and an infected aortic pseudoaneurysm. Taking into consideration the general and local septic process, repeat reconstruction of the thoracic aorta was impossible due to the risk for generalization of the infectious process and fatal complications. Read More

J Cardiovasc Surg (Torino) 2019 Apr 15. Epub 2019 Apr 15.

St George's Vascular Institute, St George's Hospital, London, UK.

Introduction: Short stay endovascular aneurysm repair pathways (SS-EVAR) provide potential advantages to both healthcare providers and patients. However, these benefits must be carefully balanced against the inherent risks to patient safety and tariff penalties associated with unplanned readmissions.

Evidence Acquisition: A literature review was performed using the databases MEDLINE, Embase and Cochrane Library up until March 2019. Read More

Vasc Specialist Int 2019 Mar;35(1):10-15

Division of Vascular and Endovascular Surgery, Department of Surgery, College of Medicine, Daegu Catholic University, Daegu, Korea.

Purpose: There are several commercially approved stent grafts in Korea for the treatment of abdominal aortic aneurysms (AAAs). Each device has its advantages and disadvantages based on the patient's anatomy and the clinical situation. The Zenith device allows accurate and precise endograft placement, whereas the Endurant device has improved flexibility and trackability. Read More

BMC Infect Dis 2019 Apr 16;19(1):326. Epub 2019 Apr 16.

Bacteriology Laboratory, Department of Genetics and Laboratory Medicine, Geneva University Hospitals, rue Gabrielle Perret-Gentil 4, 1211, Geneva 14, Switzerland.

Background: Endograft infection is a rare but extremely dangerous complication of aortic repair (25-100% of mortality). We describe here the first case of Listeria monocytogenes abdominal periaortitis associated with a vascular graft. We also discuss the differential diagnosis of periaortitis and provide a literature review of L. Read More

Vasc Endovascular Surg 2019 Apr 16:1538574419840878. Epub 2019 Apr 16.

1 Department of Vascular Surgery, General Hospital of People's Liberation Army, Beijing, China.

Objective: This meta-analysis was to evaluate the effect of remote ischemic preconditioning (RIP) on complications after abdominal aortic aneurysm repair.

Methods: A literature search was conducted in Google scholar, PubMed, Embase, and Web of Science databases up to February 2019. The pooled risk difference (RD) as well as their 95% confidence interval (CI) were calculated by RevMan 5. Read More

Vascular 2019 Apr 16:1708538119844041. Epub 2019 Apr 16.

1 Division of Cardiovascular Medicine, The University of Kansas Medical Center, Kansas City, KS, USA.

Objectives: A hostile proximal neck anatomy is the most common cause of abdominal aorta endovascular aneurysm repair failure leading to a higher risk of device migration, proximal type I endoleak, and subsequent open surgical repair. Endostapling is a technique to attain better fixation of the endograft to the aortic wall, and the only available device in the USA is Aptus Heli-FX EndoAnchor system (Medtronic Vascular, Santa Rosa, CA, USA). Preliminary data have shown efficacy and safety of its use, and the aim of this study is to assess device-related adverse events in real-world clinical use. Read More

Clin Sci (Lond) 2019 Apr 2;133(7):805-819. Epub 2019 Apr 2.

Department of Translational Medical Sciences, Università degli Studi della Campania 'L. Vanvitelli', Naples, Italy.

Autophagy is a conserved process by which cytoplasmatic elements are sequestered in vesicles and degraded after their fusion with lysosomes, thus recycling the precursor molecules. The autophagy-mediated removal of redundant/harmful/damaged organelles and biomolecules plays not only a replenishing function, but protects against stressful conditions through an adaptive mechanism. Autophagy, known to play a role in several pathological conditions, is now gaining increasing attention also in the perspective of the identification of the pathogenetic mechanisms at the basis of ascending thoracic aortic aneurysm (TAA), a localized or diffused dilatation of the aorta with an abnormal widening greater than 50 percent of the vessel's normal diameter. Read More

J Mol Cell Cardiol 2019 Apr 13. Epub 2019 Apr 13.

State Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. Electronic address:

Abdominal aortic aneurysm (AAA) is accepted as a chronic vascular inflammatory disease. However, how the inflammatory response is regulated during AAA formation is not fully understood. This study was undertaken to determine whether the long noncoding RNA (lncRNA) H19 (H19) promotes AAA formation by enhancing aortic inflammation. Read More

Radiol Case Rep 2019 Jun 3;14(6):723-728. Epub 2019 Apr 3.

Department of Interventional Radiology, AORN ``A. Cardarelli'', Via A. Cardarelli 9, 80131 Naples, Italy.

Visceral artery aneurysms are very rare and aneurysms of the celiac trunk are the rarest ones: they are in most cases asymptomatic and their detection is frequently incidental. In this article we report the case of a man affected by severe abdominal pain with a huge aneurysm of the celiac trunk, first successfully treated with coil embolization, but, after 10 months, another endovascular embolization was required for deployment of the metallic coils previously released, ahead into the fund of the sac with recanalization of the aneurysm. A second endovascular treatment was performed with other coils and Amplatzer-Plug. Read More

JCSM Clin Rep 2018 Jan-Jun;3(1)

Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202.

Aims: Repair of abdominal aortic aneurysms (AAA) decreases the incidence of rupture and death. In cancer patients, sarcopenia has been associated with increased surgical complications and mortality. The impact of sarcopenia on survival after AAA repair has yet to be described. Read More

EBioMedicine 2019 Apr 11. Epub 2019 Apr 11.

Laboratorio de Patología Vascular, FIIS-Fundación Jiménez Díaz-Universidad Autónoma, Madrid, Spain; CIBER de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain. Electronic address:

Background: High-density lipoproteins (HDL) are a complex mixture of lipids and proteins with vasculoprotective properties. However, HDL components could suffer post-translational modifications (PTMs) under pathological conditions, leading to dysfunctional HDL. We studied whether HDL are modified in abdominal aortic aneurysm (AAA) and the effect on HDL functionality. Read More

Nihon Shokakibyo Gakkai Zasshi 2019 ;116(4):344-352

Department of Gastroenterology, Hiroshima City Asa Citizens Hospital.

A man in his 40s with no remarkable past medical history was referred to our hospital with acute exacerbation of nonspecific epigastric pain by another hospital on the morning of the day of presentation. Though vital signs were stable, tenderness and guarding were observed over the entire abdomen. Contrast-enhanced computed tomography (CT) revealed a giant retroperitoneal hematoma due to a ruptured aneurysm close to the superior mesenteric artery. Read More

Ann Biomed Eng 2019 Apr 8. Epub 2019 Apr 8.

Department of Mechanical Engineering, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA.

Abdominal aortic aneurysm (AAA) is a vascular disease characterized by the enlargement of the infrarenal segment of the aorta. A ruptured AAA can cause internal bleeding and carries a high mortality rate, which is why the clinical management of the disease is focused on preventing aneurysm rupture. AAA rupture risk is estimated by the change in maximum diameter over time (i. Read More

Angiology 2019 Apr 8:3319719838892. Epub 2019 Apr 8.

1 Department of Clinical Epidemiology and Public Health, University Hospital de la Santa Creu i Sant Pau IIB Sant Pau, Barcelona, Spain.

The objective of this study was to provide evidence-based recommendations for endovascular aneurysm repair (EVAR) versus open surgical repair (OSR) for patients with a nonruptured abdominal aortic aneurysm (AAA). We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement and adhered to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework. Both low- and high surgical risk patients treated with EVAR showed decreased 30-day mortality, but the low-risk group had no differences in 4-year mortality. Read More

J Vasc Surg 2019 Apr 4. Epub 2019 Apr 4.

Division of Vascular Surgery, Department of Surgery, University Medical Centre Groningen, Groningen, The Netherlands.

Background: In this study, we systematically reviewed late open conversions after failed endovascular aneurysm repair (EVAR), assessed the methodologic quality of the included studies, and performed a meta-analysis on the 30-day mortality rates for urgent and elective late conversions.

Methods: Electronic databases were systematically searched for studies published up to June 2018 that focused on late open conversion of failed EVAR (ie, >30 days after the initial EVAR), reported the primary outcome of 30-day mortality rate, and distinguished the 30-day mortality rate between urgent and elective late conversions. Two independent reviewers assessed the methodologic quality of the included studies with the Methodological Index for Non-Randomized Studies. Read More

Redox Biol 2019 Mar 29;24:101185. Epub 2019 Mar 29.

Division of Molecular Medicine, Department of Anesthesiology, Division of Cardiology, Department of Medicine, Cardiovascular Research Laboratories, David Geffen School of Medicine at University of California Los Angeles, 650 Charles E. Young Drive, Los Angeles, CA, 90095, USA. Electronic address:

Hypertension and abdominal aortic aneurysm (AAA) are severe cardiovascular diseases with incompletely defined molecular mechanisms. In the current study we generated dihydrofolate reductase (DHFR) knockout mice for the first time to examine its potential contribution to the development of hypertension and AAA, as well as the underlying molecular mechanisms. Whereas the homozygote knockout mice were embryonically lethal, the heterozygote knockout mice had global reduction in DHFR protein expression and activity. Read More

J Biomech 2019 Mar 27. Epub 2019 Mar 27.

Mechanical Engineering Department, Northern Arizona University, Flagstaff, AZ, USA. Electronic address:

Flow stagnation and residence time (RT) are important features of diseased arterial flows that influence biochemical transport processes and thrombosis. RT calculation methods are classified into Eulerian and Lagrangian approaches where several measures have been proposed to quantify RT. Each of these methods has a different definition of RT, and it is not clear how they are related. Read More

Cardiovasc Intervent Radiol 2019 Apr 4. Epub 2019 Apr 4.

Division of Vascular Surgery, Department of General Surgery, First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China.

Objectives: The aim of this study was to evaluate the clinical course and vascular remodeling of spontaneous isolated intramural hematoma of the superior mesenteric artery (SIHSMA) after treatment.

Methods: In this retrospective study, 24 consecutive patients with SIHSMA admitted from January 2009 through December 2016 were included in this study. The clinical characteristics, type and location of the dissection, clinical outcome and vascular remodeling were analyzed retrospectively. Read More

J Cardiovasc Surg (Torino) 2019 Apr 3. Epub 2019 Apr 3.

Department of Vascular Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.

The "new" and updated European Society for Vascular Surgery (ESVS) 2019 Clinical Practice Guidelines on the Management of Abdominal Aorto-iliac Artery Aneurysm, published in the 2019 January issue of the European Journal of Vascular and Endovascular Surgery, is an extensive document offering 125 recommendations of clinical importance on the management of AAA, accompanied by a comprehensive supporting text that summarizes the literature and motivates the positions made. Several new topics, not addressed in the previous guidelines, are included. Here we summarises the most important news in the new ESVS 2019 clinical practice guidelines on the management of abdominal aorto-iliac artery aneurysm. Read More

Rofo 2019 Apr 4. Epub 2019 Apr 4.

Institut für Radiologie und Nuklearmedizin, Kantonsspital Winterthur, Switzerland.

Aim:  Segmental arterial mediolysis (SAM) is a rare non-atherosclerotic, non-inflammatory, non-infectious arteriopathy in middle-aged patients that tends to affect medium-sized splanchnic arteries typically leading to dissecting aneurysms which in case of rupture have a high mortality. Treatment options include watchful waiting and endovascular or surgical intervention. There are no official treatment guidelines and to the best of our knowledge, there has not been any report of extensive exclusion of multiple splanchnic vessel regions in affected patients to date. Read More

Proc Natl Acad Sci U S A 2019 Apr 3;116(16):8038-8047. Epub 2019 Apr 3.

Systems Immunity Research Institute, School of Medicine, Cardiff University, CF14 4XN Cardiff, United Kingdom;

Abdominal aortic aneurysm (AAA) is an inflammatory vascular disease with high mortality and limited treatment options. How blood lipids regulate AAA development is unknown. Here lipidomics and genetic models demonstrate a central role for procoagulant enzymatically oxidized phospholipids (eoxPL) in regulating AAA. Read More

Biosci Rep 2019 Apr 3. Epub 2019 Apr 3.

Department of Cardiology, Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, Zhejiang, China., hangzhou, 310009, China

Angiotensin (Ang) A is formed by the decarboxylation of the N terminal residue of AngII. This study determined whether this one amino acid change impacted effects of AngII on abdominal aortic aneurysm (AAA) formation in mice. Computational analyses implicated that AngA had comparable binding affinity to both AngII type 1 and 2 receptors as AngII. Read More

Perm J 2019 ;23

Respiralab, Respiralab Research Group, Guayaquil, Ecuador.

Introduction: Lymphangioleiomyomatosis (LAM) is a multisystemic disorder characterized by the proliferation, metastasis, and infiltration of smooth muscle cells in the lung and other tissues. Although LAM is rarely seen in men, it is usually detected in women during the third decade of life. Renal microaneurysms have been reported in patients with LAM, but abdominal aneurysms have not. Read More

Case Reports Hepatol 2019 26;2019:6272419. Epub 2019 Feb 26.

Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.

To present a first reported case of ruptured multifocal hepatic aneurysms in a woman with systemic lupus erythematosus (SLE) who was treated successfully with transcatheter arterial embolization (TAE) in literature, similar cases in the previous English literature were also reviewed and analyzed to summarize the clinical manifestations, management, and outcome in these patients. The data were gathered from the medical record and literature reviews were searched from PudMed. In our review, patients with SLE-related hepatic aneurysms were often middle-aged females. Read More

Heart 2019 Apr 1. Epub 2019 Apr 1.

School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Objective: To assess the association of metformin prescription with the risk of aortic aneurysm, aortic aneurysm events and the enlargement of abdominal aortic aneurysm (AAA).

Design: Systematic review and meta-analysis.

Methods: We searched PubMed, Embase and Scopus for epidemiological studies up to November 2018. Read More

J Mol Cell Cardiol 2019 Mar 30;130:131-139. Epub 2019 Mar 30.

The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education，Chinese Ministry of Health and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Qilu Hospital of Shandong University, Jinan, Shandong, China; School of Pharmacy, Hubei University of Science and Technology, Xianning, Hubei, China. Electronic address:

Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease without an effective pharmaceutical treatment. Liver kinase B1 (LKB1), a tumor suppressor, is a central regulator of cell polarity and energy homeostasis. However, the role of LKB1 in the development of AAA has not been explored. Read More

J Vasc Surg 2019 Mar 29. Epub 2019 Mar 29.

Department of Vascular Surgery, Rijnstate Hospital, Arnhem, The Netherlands.

Background: The 1-year results of the use of the Nellix (Endologix Inc, Irvine, Calif) endovascular aneurysm sealing (EVAS) device were initially promising. However, midterm complications including migration and aneurysm growth occurred more frequently than expected, which provided an incentive to refine the instructions for use. Strategies for the management of complications arising after endovascular aneurysm repair are often not applicable for EVAS, given the unique configuration of the Nellix device, and new techniques are needed. Read More

Vasc Endovascular Surg 2019 Apr 1:1538574419840873. Epub 2019 Apr 1.

1 Department of Vascular Surgery, Danbury Hospital, Danbury, CT, USA.

We describe a unique case of an acute type B aortic dissection in a patient with a history of a previously placed infrarenal aortic stent for an abdominal aortic aneurysm. The patient presented with a hypertensive emergency and left lower extremity ischemia, and imaging revealed complete collapse of the previously placed stent graft with extension into the iliac limbs. He underwent emergent endovascular intervention. Read More

J Endovasc Ther 2019 Apr 2:1526602819838870. Epub 2019 Apr 2.

1 Department of Vascular Surgery, St Franziskus Hospital, Münster, Germany.

EJVES Short Rep 2019 24;42:38-42. Epub 2019 Jan 24.

Department of Vascular Surgery, St. Franziskus Hospital Münster, Clinic of Vascular and Endovascular Surgery, University of Münster, Germany.

Introduction: The aim was to describe possible management of a persistent gutter related type Ia endoleak after treatment of a symptomatic pararenal aortic aneurysm with the chimney endovascular technique.

Report: A 77 year old man with a symptomatic 6 cm pararenal aortic aneurysm was referred. Computed tomography angiography (CTA) showed a pararenal aortic aneurysm with involvement of both renal arteries and extension up to the superior mesenteric artery. Read More

Ann Vasc Dis 2019 Mar;12(1):91-94

Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.

The patient had an infected abdominal aortic aneurysm. Aneurysmectomy and in situ reconstruction of the abdominal aorta using the bilateral superficial femoral veins with omentopexy were performed. On postoperative day 18, hematemesis and melena occurred. Read More

Ann Vasc Dis 2019 Mar;12(1):87-90

Department of Cardiovascular Surgery, Tsukuba Medical Center Hospital, Tsukuba, Ibaraki, Japan.

This report presents the case of a 43-year-old man with inferior vena cava (IVC) compression caused by a retroperitoneal hematoma following an abdominal aortic aneurysm (AAA) rupture. Preoperative computed tomography scans revealed an infrarenal AAA with a retroperitoneal hematoma nearly occluding the IVC. After emergency aortic grafting, IVC thrombosis, deep venous thrombosis (DVT), and pulmonary thromboembolism (PTE) arose. Read More

Ann Vasc Dis 2019 Mar;12(1):50-54

Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.

: Abdominal aortic aneurysm (AAA) in patients <30 years old is relatively rare. We retrospectively analyzed patients <30 years who received an AAA replacement. : Among 3,003 patients who received an AAA replacement during the last 40 years, 10 patients <30 years old were retrospectively reviewed. Read More

Ann Vasc Dis 2019 Mar;12(1):30-35

Department of Cardiovascular Surgery, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.

The usefulness of abdominal duplex ultrasound (DUS) for the detection of endoleaks after endovascular aneurysm repair (EVAR) was evaluated. Among 286 patients who underwent EVAR between September 2007 and July 2017, 241 patients were followed up using abdominal DUS. Endoleaks were detected in 74 patients (31%), who were divided into enlarged and nonenlarged sac groups. Read More

Ann Vasc Dis 2019 Mar;12(1):6-13

Division of Vascular Surgery, Department of Surgery and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan.

Endovascular aneurysm repair (EVAR) has become the standard therapy alongside open surgery repair (OSR) for abdominal aortic aneurysm (AAA) and it is rapidly becoming prevalent. There has been substantial technical progress with respect to EVAR since its introduction. Technical contrivance can be used to manage even inappropriate EVAR cases, including those involving a hostile neck, deficient access route, or aneurysm rupture. Read More

Ann Vasc Surg 2019 Mar 26. Epub 2019 Mar 26.

Department of Hygiene and Public Health, Nippon Medical School. Electronic address:

Int J Cardiol 2019 Jun 19;285:97-102. Epub 2019 Mar 19.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

Background: Endovascular aneurysm repair (EVAR) has revolutionized the treatment of abdominal aortic aneurysm (AAA) disease. However, the survival advantage is lost in the long term due the occurrence of endoleaks affecting the late rupture of aneurism sac. Few data are available on the role of blood pressure control in affecting the incidence of type 2 endoleaks in patients undergoing EVAR. Read More

Biochimie 2019 Mar 26;162:1-7. Epub 2019 Mar 26.

Université Côte d'Azur, CHU, Inserm U1065, C3M, Nice, France; Division of Cardiovascular Medicine, Department of Medicine, University of Cambridge, Cambridge, CB20 SZ, UK; Institut National de la Santé et de la Recherche Médicale (Inserm), Unit 970, Paris Cardiovascular Research Center, 75015, Paris, France; Department of Clinical Biochemistry, University Hospital of Nice, France. Electronic address:

Objectives: The potential implication of micro-RNAs (miRs) in the negative association between diabetes and abdominal aortic aneurysm (AAA) has so far never been addressed. The aim of this study was to compare miR expression between diabetic and non-diabetic patients with AAA.

Methods: Ten diabetic patients were prospectively included and compared to 10 age- and sex-matched non-diabetic patients with infrarenal AAA. Read More

Can Assoc Radiol J 2019 Mar 25. Epub 2019 Mar 25.

Department of Radiology, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada; Department of Diagnostic Imaging, Hamilton General Hospital, Hamilton Health Sciences, Hamilton, Ontario, Canada.

Purpose: The purpose of this study is to introduce the aortic bulge sign, a finding observed retrospectively on computed tomography prior to the acute presentation of aortoenteric fistula, and to determine its interobserver reliability.

Methods: Following research ethics board approval, all cases of aortoenteric fistula at our institution occurring from 2011-2015 were identified retrospectively. All previous computed tomography images of patients who eventually developed aortoenteric fistula were reviewed by a single observer for the presence of a potentially predictive finding of fistulization, the aortic bulge sign. Read More

J Vasc Surg 2019 Mar 25. Epub 2019 Mar 25.

Division of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, Minn.

Bilateral acute limb ischemia after endovascular aneurysm repair is extremely rare. We present the case of a 70-year-old man treated by endovascular aneurysm repair for a 7.9-cm asymptomatic infrarenal abdominal aortic aneurysm using a bifurcated modular GORE EXCLUDER endoprosthesis (W. Read More

J Vasc Surg 2019 Mar 25. Epub 2019 Mar 25.

Division of Vascular Surgery and Endovascular Therapy, University of Florida, Gainesville, Fla. Electronic address:

Objective: Most would agree that at least 1-year survival is necessary after intact abdominal aortic aneurysm (AAA) repair to appropriately justify the cost and risk of the procedure. No validated clinical decision instruments exist to predict survival after endovascular aneurysm repair (EVAR) beyond the perioperative period. The purpose of this analysis was to create a preoperative prediction model for 1-year mortality after EVAR for intact AAA in the Society for Vascular Surgery Vascular Quality Initiative. Read More

J Vasc Surg 2019 Mar 25. Epub 2019 Mar 25.

Department of Surgery, Sacramento VA Medical Center, Mather, Calif; Department of Surgery, University of California, Davis, Sacramento, Calif. Electronic address:

Objective: In 2007, Medicare established ultrasound screening guidelines to identify patients at risk for abdominal aortic aneurysm (AAA). The purpose of this study was to evaluate AAA diagnosis rates and compliance with screening during 10 years (2007-2016) of the Screen for Abdominal Aortic Aneurysms Very Efficiently Act implementation within a regional health care system.

Methods: A retrospective chart review of all patients screened for AAA from 2007 to 2016 within a regional Veterans Affairs health care system was conducted. Read More

BMC Cardiovasc Disord 2019 Mar 29;19(1):72. Epub 2019 Mar 29.

Tumor Etiology and Screening Department of Cancer Institute and General Surgery, The First Hospital of China Medical University, No.155 Nanjing Bei Street, Heping District, Shenyang, Liaoning Province, People's Republic of China, 110001.

Background: A cross-talk between Toll-like receptor 4 (TLR4) and matrix metalloproteinase 9 (MMP9) plays a vital role in aortic pathophysiology. The objective of this study was to evaluate the interactions between TLR4 and MMP9 polymorphisms in the risk of aortic aneurysm (AA) and its subtypes.

Methods: KASP method was used to detect polymorphisms of TLR4 (rs11536889 and rs1927914) and MMP9 (rs17576) in 472 AA patients and 498 controls. Read More

Br J Surg 2019 Mar 27. Epub 2019 Mar 27.

Elitary Research Centre of Individualized Medicine in Arterial Disease (CIMA), Department of Cardiology, Odense University Hospital, Odense, Denmark.

Background: The challenge of managing age-related diseases is increasing; routine checks by the general practitioner do not reduce cardiovascular mortality. The aim here was to reduce cardiovascular mortality by advanced population-based cardiovascular screening. The present article reports the organization of the study, the acceptability of the screening offer, and the relevance of multifaceted screening for prevention and management of cardiovascular disease. Read More

Int Angiol 2019 Mar 27. Epub 2019 Mar 27.

Department of Cardiovascular Surgery, Tokyo Medical University, Tokyo, Japan.

Objective: To evaluate the 4-year results of the Endurant stent graft in the treatment of abdominal aortic aneurysm (AAA) or common iliac artery aneurysm (CIAA).

Methods: Between June 2012 and January 2014, 50 consecutive Japanese AAA and CIAA patients were treated with the Endurant stent graft at Tokyo Medical University Hospital.

Results: Estimated freedom from overall mortality, aneurysm-related mortality, and secondary interventions at 4 years was 61. Read More

J Cardiovasc Surg (Torino) 2019 Mar 22. Epub 2019 Mar 22.

Department of Thoracic and Vascular Surgery, Ghent University Hospital, Ghent, Belgium -

Background: Concomitant malignant disease and abdominal aortic aneurysms (AAA) represent a challenging issue in terms of treatment priority, timing and perspectives. This narrative review provides an overview of the available literature managing AAA and concomitant malignant disease.

Methods: We conducted a literature search of all the English-language medical literature in Medline (through PubMed), Embase, Clinical Trial databases and the Cochrane Library up to December 31st, 2018. Read More

Case Rep Infect Dis 2019 19;2019:5369707. Epub 2019 Feb 19.

Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Q fever is a zoonotic bacterial infection caused by . Chronic Q fever comprises less than five percent of all Q fever cases and, of those, endocarditis is the most common presentation (up to 78% of cases), followed by vascular involvement. Risk factors for chronic Q fever with vascular involvement include previous vascular surgery, preexisting valvular defects, aneurysms, and vascular prostheses. Read More

J Lipid Res 2019 Mar 26. Epub 2019 Mar 26.

University of the Sunshine Coast, Australia;

Abdominal aortic aneurysm (AAA) is an important cause of death in older adults which has no current drug therapy. Inflammation and abnormal redox status are believed to be key pathogenic mechanisms for AAA. In light of evidence correlating inflammation with aberrant fatty acid profiles, this study compared erythrocyte fatty acid content in 43 AAA patients (diameter 3. Read More

Asian J Surg 2019 Mar 23. Epub 2019 Mar 23.

Department of Vascular Surgery, Beijing Hospital, National Center of Gerontology, Beijing, 100730, PR China; Peking Union Medical College, Chinese Academy of Medical Science, Beijing, 100730, PR China. Electronic address:

To provide a meta-analysis of studies evaluating long-term all-cause mortality, aneurysm-related mortality and re-intervention after open or endovascular repair for abdominal aortic aneurysm. Electronic bibliographic sources were interrogated using a combination of free text and controlled vocabulary searches to identify studies comparing the long-term outcomes of open and endovascular repair for abdominal aortic aneurysm. The review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement standards. Read More

Vasc Endovascular Surg 2019 Mar 26:1538574419839251. Epub 2019 Mar 26.

1 Department of Cardiovascular Surgery, Yokohama Sakae Kyosai Hospital, Yokohama-Shi, Kanagawa, Japan.

Introduction:: Venous thromboembolism (VTE) of the lower extremities frequently occurs after surgery. It is unknown whether the complication of renal vein thrombosis (RVT) develops after an open repair (OR) for abdominal aortic aneurysm (AAA). Furthermore, anticoagulation therapy with apixaban, a direct oral anticoagulant (DOAC), has not been described as treatment for RVT in such cases. Read More