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J Vasc Surg 2020 Jun 29. Epub 2020 Jun 29.

MedStar Health, Washington DC.

Endovascular aortic aneurysm repair of complex aortic aneurysms requires incorporation of side branches using specially designed aortic stent-grafts with fenestrations, directional branches or parallel stent-grafts. These techniques have been increasingly utilized and reported in the literature. The purpose of this document is to clarify and update terminology, classification systems, measurement techniques and end-point definitions that are recommended for reports dealing with endovascular repair of complex abdominal and thoracoabdominal aortic aneurysms involving the renal and mesenteric arteries. Read More

Ann Vasc Surg 2020 Jun 29. Epub 2020 Jun 29.

Center for Health Technology and Services Research (CINTESIS) and Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS), Faculty of Medicine, University of Porto.

Introduction: The recommendations about the preferred type of elective repair of abdominal aortic aneurysm (AAA) still divides guidelines committees, even nowadays. The aim is to assess outcomes after AAA repair focusing on differences between endovascular (EVAR) and open repair (OSR).

Methods: Observational retrospective cohort study of consecutive patients submitted to elective AAA repair at a tertiary centre, 2009-2015. Read More

PLoS One 2020 2;15(7):e0235553. Epub 2020 Jul 2.

Department of Cardiovascular Physiology and Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Aortic aneurysm refers to dilatation of the aorta due to loss of elasticity and degenerative weakening of its wall. A preventive role for osteoprotegerin (Opg) in the development of abdominal aortic aneurysm has been reported in the CaCl2-induced aneurysm model, whereas Opg was found to promote suprarenal aortic aneurysm in the AngII-induced ApoE knockout mouse aneurysm model. To determine whether there is a common underlying mechanism to explain the impact of Opg deficiency on the vascular structure of the two aneurysm models, we analyzed suprarenal aortic tissue of 6-month-old ApoE-/-Opg-/- mice after AngII infusion for 28 days. Read More

Lab Invest 2020 Jul 1. Epub 2020 Jul 1.

Department of Vascular Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, 116027, Liaoning, People's Republic of China.

Abdominal aortic aneurysm (AAA) is a potential lethal disease that is defined by an irreversible dilatation (>50%) of the aorta. During AAA expansion, the aortic wall is often remodeled, which is featured by extracellular matrix (ECM) degeneration, medial and adventitial inflammation, depletion and phenotypic switching of vascular smooth muscle cells (SMCs). Recent studies have suggested microRNAs as vital regulators for vascular SMC function. Read More

J Atheroscler Thromb 2020 Jul 2. Epub 2020 Jul 2.

Department of Cardiovascular Surgery, Second Affiliated Hospital of Kunming Medical University.

Aim: Deepening our understanding of the molecular mechanism of abdominal aortic aneurysm (AAA) progression will help set up novel avenues for therapeutic target identification. Our aim here was to unveil the mechanism function of STAT3 in AAA progression.

Methods: We investigated the functional role of STAT3 in AAA by evaluating vascular smooth muscle cell (VSMC) apoptosis and proliferation via terminal deoxynucleotidyl transferase dUTP nick end labeling, western blotting, 5-ethynyl-2´-deoxyuridine, and Cell Counting Kit-8 assays. Read More

Vasc Specialist Int 2020 Jun;36(2):82-88

Department of Medical Statistics, College of Medicine, Daegu Catholic University, Daegu, Korea.

Purpose: The correlation of initial anatomy of the aneurysm, aneurysmal remodeling and endoleaks is controversial. We performed a retrospective study to measure aneurysmal remodeling with time, and to assess the structural changes in the aneurysm neck after endovascular aneurysm repair (EVAR).

Materials And Methods: From January 2013 to February 2018, 108 patients with abdominal aortic aneurysms (AAA) underwent EVAR. Read More

Vasc Specialist Int 2020 Jun;36(2):71-81

Division of Vascular Surgery, Department of Surgery, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea.

Purpose: To evaluate the aortic neck anatomy in Korean patients with abdominal aortic aneurysms (AAAs).

Materials And Methods: We examined computed tomography scans of 343 patients with AAAs (≥5.5 cm for men or ≥5 cm for women) between 2009 and 2018. Read More

Cardiovasc Ultrasound 2020 Jul 1;18(1):24. Epub 2020 Jul 1.

Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

Background: Accurate measurement of the maximum aortic diameter (Dmax) is crucial for patients with abdominal aortic aneurysm (AAA). Aortic computed tomography (CT) provides accurate Dmax values by three-dimensional (3-D) reconstruction but may cause nephrotoxicity because of contrast use and radiation hazard. We aimed to evaluate the accuracy of a novel semi-automated 3-D ultrasonography (3-D US) system compared with that of CT as a reference. Read More

Vascular 2020 Jul 1:1708538120936831. Epub 2020 Jul 1.

Department of Medicine, Surgery and Neuroscience, Vascular Surgery Unit, University of Siena, Siena, Italy.

Objective: In the last decades, life expectancy has increased worldwide considerably. Traditionally, very elderly patients have been considered too frail to undergo major vascular interventions. Considering that abdominal aortic aneurysm is an age-related disease, there is an increasing need of a correct management of the disease even in nonagenarians, but data are still scarce. Read More

J Vasc Res 2020 Jul 1:1-15. Epub 2020 Jul 1.

Department of Vascular Surgery, The First Hospital of China Medical University, Shenyang, China,

Introduction: CD4-positive T lymphocytes (CD4 cells) play a significant role in human abdominal aortic aneurysm (AAA). However, we know little about the role of the different CD4 subtypes.

Objective: We aimed to discover the circulatory CD4 phenotypic marker profile and the roles of the newly found T helper cell 9 (Th9) and follicular helper T cells (Tfh) and that of inflammasomes in CD4 cells from AAA patients. Read More

Cochrane Database Syst Rev 2020 Jul 1;7:CD001835. Epub 2020 Jul 1.

Robbins Institute for Health Policy and Leadership, Baylor University, Waco, USA.

Background: An abdominal aortic aneurysm (AAA) is an abnormal ballooning of the major abdominal artery. Some AAAs present as emergencies and require surgery; others remain asymptomatic. Treatment of asymptomatic AAAs depends on many factors, but the size of the aneurysm is important, as risk of rupture increases with aneurysm size. Read More

J Surg Case Rep 2020 Jun 22;2020(6):rjaa186. Epub 2020 Jun 22.

Icahn School of Medicine at Mount Sinai, NY, NY.

Diverticulitis, though a common gastrointestinal disease, is rare following open-heart surgery. There is insufficient data regarding its incidence and management post-cardiac surgery. Especially in patients with atypical presentation, diagnosis and management can be challenging. Read More

Vasc Health Risk Manag 2020 9;16:215-229. Epub 2020 Jun 9.

Faculty of Medicine, Universiti Kebangsaan Malaysia, UKM Medical Center, Kuala Lumpur 56000, Malaysia.

Introduction: Abdominal aortic aneurysm (AAA) and coronary artery disease (CAD) share common risk factors. The objective of this study was to determine the prevalence of undiagnosed AAA in patients with angiographically diagnosed significant CAD.

Patients And Methods: Male patients aged 50 years and above (including indigenous people) with angiographically diagnosed significant CAD in the recent one year were screened for AAA. Read More

Int J Mol Sci 2020 Jun 28;21(13). Epub 2020 Jun 28.

Angiology and Vascular Surgery Service, La Fe University and Polytechnic Hospital, 46026 Valencia, Spain.

microRNAs (miRNAs) are small RNAs that regulate different biological processes. Our objective was to identify miRNAs dysregulated in plasma and tissue of patients with abdominal aortic aneurysm (AAA) and explore new potential targets involved in AAA. Fifty-seven subjects were recruited for a plasma study (30 AAA patients, 16 healthy volunteers and 11 patients with atherosclerosis). Read More

J Cardiopulm Rehabil Prev 2020 Jul;40(4):215-223

Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, Michigan (Drs Ehrman and Keteyian); The Heart and Vascular Institute, Hartford Hospital, Hartford, Connecticut (Drs Fernandez and Thompson); VA Medical Center, Palo Alto, California (Dr Myers); and University Health Network, Toronto, Ontario, Canada (Dr Oh).

Background: Some patients who participate in cardiac rehabilitation have aortic abnormalities, including abdominal and thoracic aneurysm (AAA and TAA, respectively). There is scant guidance on implementing exercise training in these individuals. This article reviews the epidemiology, diagnostic process, medical issues, and the available exercise training literature, and provides recommendations for performing regular exercise. Read More

Ann Vasc Surg 2020 Jun 27. Epub 2020 Jun 27.

Division of Vascular Surgery, Department of Surgery, University of Washington, Seattle, WA. Electronic address:

Objective: First generation "off-the-shelf" branched endovascular stent grafts are in development for treatment of thoraco-abdominal aneurysms (TAAA). Prior studies have assessed eligibility rates among highly selected cohorts of patients referred for endovascular treatment, and the broader applicability of these devices to all patients with TAAA is unknown. The aims of this study were to assess the overall suitability of the 3 commercial 4-branched devices with or without adjunct procedure(s) in an unselected cohort of patients with TAAA, and to identify areas for improvement in the next generation of devices. Read More

Vascular 2020 Jun 29:1708538120937127. Epub 2020 Jun 29.

Department of Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.

Objectives: To compare preoperative coagulation and fibrinolysis activity and incidence of perioperative complications between patients undergoing vascular procedures for peripheral artery disease and abdominal aortic aneurysm.

Methods: This is a substudy of a prospective observational cohort study (VISION; NCT00512109) in which we recruited patients aged ≥45 years, undergoing surgery for peripheral artery disease and abdominal aortic aneurysm. Blood samples were obtained 24 h preoperatively to measure platelet count, concentrations of coagulation coagulation (fibrinogen, factor VIII, von Willebrand factor:Ristocetin cofactor, antithrombin III), fibrinolysis (dimer D, plasmin-antiplasmin complexes, tissue plasminogen activator) markers and level of soluble CD40 ligand. Read More

J Clin Med 2020 Jun 24;9(6). Epub 2020 Jun 24.

Chair and Department of Biology and Genetics, Medical University of Lublin, 4a Chodźki St., 20-093 Lublin, Poland.

Abdominal artery aneurysm (AAA) refers to abdominal aortic dilatation of 3 cm or greater. AAA is frequently underdiagnosed due to often asymptomatic character of the disease, leading to elevated mortality due to aneurysm rupture. MiRNA constitute a pool of small RNAs controlling gene expression and is involved in many pathologic conditions in human. Read More

Ann Vasc Surg 2020 Jun 26. Epub 2020 Jun 26.

Department of Vascular Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea. Electronic address:

Purpose: Iliac limb stent grafting to the external iliac artery (EIA) is a commonly performed procedure in various situation during endovascular abdominal aneurysm repair (EVAR). However, this procedure is associated with a risk of graft occlusion. We evaluated risk factors affecting occlusion among patients who underwent iliac limb stent graft extension to the EIA. Read More

Ann Vasc Surg 2020 Jun 26. Epub 2020 Jun 26.

Department of Health Sciences Research, Robert D. and Patricia E. Kern Center for Science of Health Care Delivery Surgical Outcomes Program, Mayo Clinic, Rochester, MN.

Objective: The adverse gender disparities for women after open abdominal aortic aneurysm (AAA) repair have been well documented. The purpose of this study is to review whether these disparities extend to elective endovascular aneurysm repair (EVAR).

Methods: Non-ruptured, elective AAA were identified from the American College of Surgeons' National Quality Improvement Program (NSQIP) Targeted Participant User File (PUF) for EVAR from 2012-2017. Read More

Ann Vasc Surg 2020 Jun 26. Epub 2020 Jun 26.

Department of Vascular and Endovascular Surgery, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.

Background: Allergy to iodinated contrast (IC) agent and advanced chronic kidney disease (CKD) are major limitations to endovascular repair of abdominal aortic aneurysms (EVAR). We describe our experience combining CO assisted EVAR with intraoperative contrast-enhanced ultrasound (CEUS) in an attempt to avoid contrast induced allergy or nephropathy.

Methods: Observational cohort study using prospectively acquired data on patients undergoing CO-assisted EVAR in single institution. Read More

Ann Vasc Surg 2020 Jun 26. Epub 2020 Jun 26.

Department of Vascular Surgery, University and Hospital Trust of Verona, University of Verona-School of Medicine, Verona, Italy.

Objectives: The aim of the study is to report the early and mid-term outcomes of late open conversion (LOC) after endovascular aortic repair (EVAR) using the "New Aortic Carrefour Technique" (NACT) for preservation of the stent-graft iliac limbs. Late conversions were defined as explants >6 months after previous EVAR.

Methods: Patients treated for elective or urgent LOC after EVAR with the "New Aortic Carrefour Technique" at a single centre (2009-2019), and with ≥6 months of follow-up, were included. Read More

Ann Vasc Surg 2020 Jun 26. Epub 2020 Jun 26.

Division of Vascular Diseases and Surgery, Department of Surgery, Ohio State University Wexner Medical Center, 376 West 10(th) Avenue, Columbus, OH. Electronic address:

Objectives: Human immunodeficiency virus (HIV) is a multisystem disease and associated with vascular complications including aneurysm formation. HIV-associated aneurysms are well-documented and may present in unusual locations with concerning features. However, the majority of the literature regarding aneurysms in HIV-positive patients are limited to case series with limited data regarding aneurysm patterns. Read More

Ann Vasc Dis 2020 Jun;13(2):194-197

Department of Cardiovascular Surgery, Sendai Kousei Hospital, Sendai, Miyagi, Japan.

Iliac vein compression syndrome (IVCS) can occasionally be iatrogenic; however, iatrogenic IVCS cases occurring because of inappropriate length and positioning of vascular grafts have not been reported. We present the case of an 80-year-old woman with iatrogenic IVCS resulting from kinked and overlapping limbs of a bifurcated abdominal vascular prosthesis for an abdominal aortic aneurysm. She complained of discomfort in her left leg immediately after aortic replacement. Read More

Ann Vasc Dis 2020 Jun;13(2):183-186

Department of Cardiovascular Surgery, Teine Keijinkai Hospital, Sapporo, Hokkaido, Japan.

A primary aorto-duodenal fistula (ADF), a rare, spontaneous development of a communication between the aorta and duodenum, is a disastrous complication of an abdominal aortic aneurysm. A 73-year-old patient with primary ADF underwent emergent endovascular aneurysm repair (EVAR), followed by staged omentopexy, without removing a stent graft (SG). The patient received long-term treatment with antibiotics, and there has been no evidence of infection during a follow-up period of three years. Read More

Ann Vasc Dis 2020 Jun;13(2):151-157

Division of Cardiovascular Surgery, Department of Surgery, Kurume University School of Medicine, Kurume, Fukuoka, Japan.

: Inflammatory response is central to pathogenesis of abdominal aortic aneurysm (AAA). Recently, we reported that Syk, a signaling molecule in inflammatory cells, promotes AAA development in a mouse model. In this study, we aimed to investigate the role of Syk in human AAA pathogenesis. Read More

Comput Methods Biomech Biomed Engin 2020 Jun 27:1-11. Epub 2020 Jun 27.

Pladema - CONICET, Universidad Nacional del Centro de la Provincia de Buenos Aires, Tandil, Argentina.

Abdominal aortic aneurysm is a deadly disease that can be treated with different endovascular devices that will distinctly alter the aortic morphology. Computational methods can be used to understand the effect of anatomical changes on aortic hemodynamics. We propose a standardized method to assess morphological and hemodynamic changes of the abdominal aorta through the longitudinal axis of the vessel. Read More

Int J Cardiol 2020 Jun 25. Epub 2020 Jun 25.

Center for Primary Health Care Research, Lund University, Sweden.

Abdominal aortic aneurysm (AAA) is a life-threatening condition with a mortality rate of over 80%. Persistent smoking, which is a risk factor for AAA, has lasting effects on DNA methylation. Moreover, a plasma-amino acid, homocysteine, previously implicated in vascular diseases, including aneurysms, has well-established biological association with methylation. Read More

Ann Vasc Surg 2020 Jun 24. Epub 2020 Jun 24.

Department of Vascular and Endovascular Surgery. Ramón y Cajal´s University Hospital, Madrid, Spain.

Introduction: The presence of sac enlargement after abdominal aortic aneurysm (AAA) open repair (OR), a condition usually called perigraft-seroma (PGS) nearly always has a benign behavior. Some theories implicated for PGS formation include coagulation abnormalities, fibroblast inhibition, low-grade infection or improper graft handling.

Methods: This is a retrospective study including patients treated for AAA in 2 academic vascular surgery departments from 2007 to 2014, where one center preferably used PTFE grafts while the other's preference was mostly Dacron graft. Read More

J Coll Physicians Surg Pak 2020 May;30(5):557-558

Department of Surgery, The Aga Khan University Hospital, Karachi, Pakistan.

Null. Read More

J Endovasc Ther 2020 Jun 17:1526602820934762. Epub 2020 Jun 17.

Department of Vascular and Endovascular Surgery, University of Cologne, Germany.

To compare and contrast the midterm outcomes of the E-liac and Zenith (ZBIS) iliac branch devices (IBDs) for the preservation of the internal iliac artery (IIA) in aneurysms involving the iliac bifurcation. Between January 2014 and December 2018, 84 consecutive patients (median age 74 years; 76 men) were electively treated with the E-liac (n=44) or ZBIS (n=40) IBDs and were retrospectively analyzed to evaluate the technical success, patency, need for reintervention, and mortality associated with these devices. Technical success was achieved in 95 of 99 implantations (95. Read More

Circulation 2020 Jun 25. Epub 2020 Jun 25.

Boston University's and National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA; Department of Medicine, Section of Cardiovascular Medicine, Boston University School of Medicine, Boston, MA; Department of Cardiology, Herlev and Gentofte Hospital, Gentofte, Denmark.

Ruptured aortic aneurysm and aortic dissections are potentially preventable disorders associated with high mortality. Screening of individuals at risk may translate into elective surgical interventions and lowered mortality. It is uncertain if the risk of aortic dilation of varying degrees aggregates within families. Read More

Vascular 2020 Jun 23:1708538120914454. Epub 2020 Jun 23.

Department of Surgery, University of California San Diego, La Jolla, CA, USA.

Objectives: The role of non-steroidal anti-inflammatory drugs in aortic aneurysm disease has been debated. Animal studies demonstrated that intrathecal ketorolac reduces the inflammatory response associated with aortic clamping. However, no human-subject study evaluated this association. Read More

EBioMedicine 2020 Jun 20;57:102832. Epub 2020 Jun 20.

Department of Cardiology, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou 510515, China; Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou 510005, China. Electronic address:

Background: Identifying effective drugs to suppress vascular inflammation is a promising strategy to delay the progression of abdominal aortic aneurysm (AAA). Itaconate has a vital role in regulating inflammatory activation in various inflammatory diseases. However, the role of itaconate in the progression of AAA is unknown. Read More

ANZ J Surg 2020 Jun 23. Epub 2020 Jun 23.

Department of Vascular and Endovascular Surgery, Monash Medical Centre, Melbourne, Victoria, Australia.

Eur J Vasc Endovasc Surg 2020 Jun 19. Epub 2020 Jun 19.

Division of Vascular Surgery, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Clin Appl Thromb Hemost 2020 Jan-Dec;26:1076029620932226

School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.

This research was designed to determine the association of serum lipid peroxidation products with disease severity in patients with abdominal aortic aneurysm (AAA). In total, 76 pairs of AAA cases as well as matched controls were enrolled in our research using propensity score matching (PSM). And their malondialdehyde (MDA), lipid hydroperoxide (LPO), and glutathione peroxidase (GSH-Px) levels were also detected through enzyme-linked immunosorbent assay (ELISA). Read More

Medicine (Baltimore) 2020 Jun;99(25):e20580

Department of Vascular Surgery, The Clinical Medical School of Yangzhou University, Yangzhou.

Introduction: Protein-losing enteropathy and spontaneous isolated superior mesenteric artery dissection are both rare clinically. Protein-losing enteropathy due to superior mesenteric artery dissection is extremely rare.

Patient Concerns: A 46-year-old male with acute abdominal pain and hematochezia was diagnosed with a complete occlusion of the superior mesenteric artery because of dissection. Read More

Ann Surg 2020 Jun 19. Epub 2020 Jun 19.

Department of Surgery, Division of Surgical Oncology, The Urban Meyer III and Shelley Meyer Chair for Cancer Research, The Ohio State University Wexner Medical Center, Columbus, OH.

Objective: The aim of this study was to define the prevalence of preexisting mental illness, as well as characterize the impact of a preexisting mental illness diagnosis on postoperative outcomes.

Summary Background Data: Preoperative surgical evaluation and risk stratification have traditionally centered on optimizing physical health. The influence of mental health on postoperative surgical outcomes has not been investigated. Read More

J Endovasc Ther 2020 Jun 22:1526602820936185. Epub 2020 Jun 22.

Department of Surgery, Rijnstate, Arnhem, the Netherlands.

To compare the impact of 2 commercially available custom-made fenestrated endografts on patient anatomy. The records of 234 patients who underwent fenestrated endovascular aneurysm repair for abdominal aortic aneurysm from March 2002 to July 2016 in 2 hospitals were screened to identify those who had pre- and postoperative computed tomography angiography assessments with a slice thickness of ≤2 mm. The search identified 145 patients for further analysis: 110 patients (mean age 72. Read More

Cardiovasc Intervent Radiol 2020 Jun 21. Epub 2020 Jun 21.

Auckland Hospital, Auckland, New Zealand.

This paper reviews the development of endovascular aneurysm repair (EVAR) of infra-renal aortic and iliac artery aneurysms and considers the current status and best treatment options. The vast majority of devices are bifurcated and exclude the aneurysm utilizing the same techniques for fixation and seal. The modern EVAR procedure is usually performed in a hybrid operating theatre, utilizing image fusion and other radiation-reducing techniques and using optimized procedural techniques, including percutaneous access. Read More

Basic Clin Pharmacol Toxicol 2020 Jun 21. Epub 2020 Jun 21.

Department of Cardiology, Diagnostic Centre, Regional Hospital Central Jutland, Silkeborg, Denmark.

A total of 1,446 participants; 65-74-year-old men diagnosed with abdominal aortic aneurysm (AAA), peripheral arterial disease (PAD) or high blood pressure (HB) in the Viborg Vascular (VIVA) screening trial, were consecutively included and randomised to a telephone counselling (TC) or no TC 3 months after being screened positive. Data from VIVA were linked to data from Danish registers from 2007 to 2016. The primary outcome was a composite outcome of proportion of days covered (PDC) by statin, antithrombotic drugs and antihypertensive agents and for each specific drug class at 6-month follow-up. Read More

Ann Vasc Surg 2020 Jun 17. Epub 2020 Jun 17.

Medical School, Democritus University, Alexandroupolis, Greece.

The use of social media for academic or research purposes is still in infancy. However, the potential of dissemination of medical knowledge through these electronic platforms is dynamically increasing. We performed a search on Twitter® collecting tweets containing the keywords 'peripheral arterial disease' (PAD) and 'abdominal aortic aneurysm' (AAA) separately and including three types of emitters. Read More

Ann Vasc Surg 2020 Jun 16. Epub 2020 Jun 16.

Division of Vascular and Endovascular Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, United States.

Objective: Aim was to analyze aortic-related outcomes after diagnosis of aortic dissection (AD), intramural hematoma (IMH), and penetrating aortic ulcer (PAU) from a population-based approach.

Methods: Retrospective review of an incident cohort of AD, IMH, and PAU patients in Olmsted County, MN from 1995-2015. Primary end-point was aortic death. Read More

Eur J Vasc Endovasc Surg 2020 Jun 16. Epub 2020 Jun 16.

Department of Medicine, Icahn School of Medicine at Mount Sinai, Mount Sinai Beth Israel, NY, USA. Electronic address:

HPB (Oxford) 2020 Jun 16. Epub 2020 Jun 16.

Department of Abdominal Organ Transplantation Surgery, Washington University School of Medicine, St Louis, MO, USA. Electronic address:

Background: Portal vein aneurysms (PVAs) are rare, though clinically challenging with post-operative mortality approaching 20% and no evidence-based treatment guidelines. We aim to describe our experience with PVAs and recommend optimum management strategies.

Methods: Demographics and clinical details of patients with PVAs admitted to our institution from 1984 to 2019 were reviewed. Read More

Biomed Pharmacother 2020 Jun 16;129:109904. Epub 2020 Jun 16.

Department of Cardiovascular Surgery, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, No.1095 Jiefang Ave, Hankou, 430000 Hubei, China. Electronic address:

Long noncoding RNAs (LncRNAs) are involved in multiple processes of human malignancy, and emerge as crucial molecules in RNA biology. However, the function of lncRNAs has not been well illustrated in abdominal aortic aneurysm (AAA). In this research, the effects of dysregulated ladybird homeobox 2 antisense RNA 1 (LBX2-AS1) or ladybird homeobox 2 (LBX2) on vascular smooth muscle cell (VSMC) biological processes were surveyed via cell counting kit-8 (CCK-8), methyl thiazolyl tetrazolium (MTT), terminal-deoxynucleoitidyl transferase mediated nick end labeling (TUNEL) and caspase-3 activity assays. Read More

J Cardiovasc Surg (Torino) 2020 Jun 19. Epub 2020 Jun 19.

Vascular Surgery, "Vita-Salute" University School of Medicine, San Raffaele Scientific Institute, Milan, Italy.

Purpose: to report three cases of spinal cord ischemia (SCI) involving the cervical- dorsal level and leading to quadriplegia and quadriparesis, following thoraco-abdominal aortic aneurysm (TAAA) endovascular repair.

Case Reports: A 79-year-old woman with an extent III TAAA was scheduled for a multi-step fenestrated/branched endovascular aortic repair. Immediately after the first step, consisting of standard proximal thoracic stent-graft implantation, she developed quadriplegia that did not resolve despite all therapeutic actions, and died as a consequence on postoperative day 32. Read More

ANZ J Surg 2020 Jun 17. Epub 2020 Jun 17.

Department of Surgery, Dubbo Base Hospital, Dubbo, New South Wales, Australia.

Background: A rural general surgeon has historically been required to perform a wide variety of subspecialist procedures. Increasingly sub-specialized training programs have restricted younger surgeons' experience in the general surgery-associated subspecialties. Time critical vascular surgical emergencies are frequently encountered by rural general surgeons. Read More

J Nucl Cardiol 2020 Jun 17. Epub 2020 Jun 17.

Biomedical Imaging Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, LS2 9NL, UK.

Background: We aim to assess the spill-in effect and the benefit in quantitative accuracy for [F]-NaF PET/CT imaging of abdominal aortic aneurysms (AAA) using the background correction (BC) technique.

Methods: Seventy-two datasets of patients diagnosed with AAA were reconstructed with ordered subset expectation maximization algorithm incorporating point spread function (PSF). Spill-in effect was investigated for the entire aneurysm (AAA), and part of the aneurysm excluding the region close to the bone (AAA). Read More