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Pediatr Dermatol 2020 May 22. Epub 2020 May 22.

Department of Plastic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

Infantile hemangioma (IH) is a benign vascular tumor that gradually involutes over several years. Rapidly involuting congenital hemangioma (RICH) is the relatively rare congenital vascular tumor that is fully grown at birth and does not undergo postnatal growth and involutes during the first year. However, after involution of both IH and RICH, some have severe sequelae, such as redundant skin or conspicuous scarring, requiring additional treatment. Read More

Indian J Dermatol Venereol Leprol 2020 May 15. Epub 2020 May 15.

Department of Dermatology, Chang Gung Memorial Hospital, Linkou Branch; School of Medicine, College of Medicine, Chang Gung University; Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.

An Bras Dermatol 2020 Jan - Feb;95(1):123-125. Epub 2019 Dec 18.

Department of Pathology, Universidade do Oeste Paulista, Presidente Prudente, SP, Brazil.

Int J Dermatol 2020 May 20;59(5):e168-e169. Epub 2020 Jan 20.

Institute of Dermatology, Catholic University and Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Rome, Italy.

Open Access Maced J Med Sci 2019 Sep 19;7(18):3093-3095. Epub 2019 Aug 19.

Military Medical Academy of Belgrade, Belgrade, Serbia.

Background: Anetodermas are rare disorders of connective tissue with a focal loss of elastic fibres in the upper and mid dermis. Two types are separated, inflammatory and non-inflammatory.

Case Reports: We report two cases of acquired anetoderma Schweniger-Buzzi type. Read More

Ann Dermatol Venereol 2020 Mar 12;147(3):194-197. Epub 2019 Dec 12.

Service de dermatologie, CHRU Besançon, 3, boulevard Alexandre-Fleming, 25000 Besançon, France.

Background: Pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE) is a rare disease clinically resembling pseudoxanthoma elasticum (PXE). Herein we report a typical case.

Patients And Methods: A 77-year-old woman consulted for an acquired papular eruption present for 4 years. Read More

J Dermatol 2020 Jan 1;47(1):82-85. Epub 2019 Nov 1.

Department of Dermatology, Iwate Medical University School of Medicine, Morioka, Japan.

Perforating pilomatricoma (PP) is a rare clinical variant of pilomatricoma presenting as a crusted or ulcerated nodule. Previous reports have suggested that the tumor cells perforate the epidermis through a process of transepithelial elimination. Here, we report six cases of PP and examine the mechanism of transepithelial elimination in PP. Read More

Case Rep Dermatol 2019 Sep-Dec;11(3):256-259. Epub 2019 Sep 30.

Department of Dermatology, Osaka University Graduate School of Medicine, Suita, Japan.

Dermatofibroma (DF) is a benign skin tumor that is well-known among dermatologists. We herein present a rare case of atrophic dermatofibroma presenting linear skin dimpling. The patient was a 25-year-old woman with a history of wild-type recessive dystrophic epidermolysis bullosa who had noticed linear concavity on her right lateral back 1 year before her initial presentation. Read More

JAMA Dermatol 2019 Sep 4. Epub 2019 Sep 4.

Department of Dermatology, Duke University Medical Center, Durham, North Carolina.

Med Clin (Barc) 2020 04 28;154(7):288. Epub 2019 Jul 28.

Departamento de Dermatología, Hospital Regional Universitario de Málaga, Málaga, España.

JAAD Case Rep 2019 May 8;5(5):466-467. Epub 2019 May 8.

Dermatology Clinic, University of Catania, Catania, Italy.

Indian J Dermatol Venereol Leprol 2020 Mar-Apr;86(2):176-177

Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Am J Dermatopathol 2019 Feb;41(2):85-117

Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.

After a review of the physiology in the formation and degradation of cutaneous elastic tissue, we describe the clinicopathologic disorders characterized by increased and decreased cutaneous elastic tissue. Cutaneous disorders characterized by increased and/or abnormal elastic tissue in the dermis include elastoma, also named nevus elasticus, dermatosis lenticularis disseminata, pseudoxanthoma elasticum, late-onset focal dermal elastosis, linear focal elastosis, elastoderma, elastofibroma dorsi, and elastosis perforans serpiginosa. In some of these conditions, the specific histopathologic diagnosis may be rendered with hematoxylin-eosin stain, whereas in other ones special elastic tissue stains are necessary to demonstrate the anomalies. Read More

J Cutan Pathol 2019 Apr 10;46(4):297-300. Epub 2019 Feb 10.

Department of Dermatology, Philadelphia College of Osteopathic Medicine, Roswell, Georgia.

Medallion-like dermal dendrocyte hamartoma is a rare congenital lesion that is more commonly seen in females. It often presents at birth on the neck or upper trunk as a well-circumscribed, atrophic patch with wrinkling of the overlying skin. Clinically, the differential diagnosis includes atrophoderma, anetoderma, and congenital atrophic dermatofibrosarcoma protuberans. Read More

Acta Derm Venereol 2019 Mar;99(3):335-336

Department of Dermatology, Pontevedra University Hospital, EOXI Pontevedra-Salnés, Centro de Especialidades Mollavao, c/ Simón Bolívar s/n., ES-36001 Pontevedra, Spain.

J Dermatol 2018 Dec 15;45(12):1459-1462. Epub 2018 Oct 15.

Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.

Anetoderma is a rare cutaneous disorder characterized by focal loss of dermal elastic tissue, resulting in macular atrophy or herniated saclike skin. Some families with hereditary anetoderma have been described, but there have been no reports on Japanese familial anetoderma so far. We herein report two Japanese sibling cases of primary anetoderma. Read More

Ann Dermatol Venereol 2018 Dec 9;145(12):777-784. Epub 2018 Oct 9.

Clinique dermatologique, université de Strasbourg, hôpitaux universitaires de Strasbourg, 1 place de l'hôpital, 67091, Strasbourg, France.

Introduction: Impairment of dermal elastic tissue occurs in different entities associated with immunoglobulins or immunoglobulin-derived protein-secreting clonal plasma cell proliferations, such as amyloid elastosis, anetodermic nodular amyloidosis or monoclonal gammopathy-associated cutis laxa. We report a case of cutaneous immunoglobulinemic amyloidosis revealed by a unique chalazodermic presentation and we review elastic tissue impairment in patients with monoclonal gammopathies.

Observation: A 67-year-old woman consulted for non-infiltrated anetodermic lesions on the upper left quadrant of her abdomen present for ten years. Read More

J Dtsch Dermatol Ges 2018 Oct;16(10):1289-1295

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Endocrinology and Diabetology, Saarland University Medical Center, Homburg, Germany.

With an incidence of 1 in 700 births, Down syndrome (DS) is not an uncommon condition. It is associated with various disorders of different organ systems. Serious disorders include cardiac defects and leukemia. Read More

Pediatr Dermatol 2018 Nov 28;35(6):e416-e417. Epub 2018 Aug 28.

Department of Dermatology, SUNY Downstate Medical Center, Brooklyn, New York.

A 15-month-old boy presented with 1-4 cm, pink edematous plaques with overlying round erosions and hemorrhagic bullae in the setting of a gastrointestinal illness and was ultimately diagnosed with bullous-type Sweet syndrome. Despite appropriate treatment with oral steroids, the patient's cutaneous lesions healed with secondary anetoderma. This case should prompt practitioners to be aware of bullous-type Sweet syndrome and the possibility of lesions healing with postinflammatory scarring. Read More

Eur J Radiol 2018 Sep 21;106:92-99. Epub 2018 Jul 21.

Deptartment of Radiology, Institute of Surgery Research and Third Affilated Hospital, Army Medical University, Chongqing 400042, China. Electronic address:

Purpose: To describe the radiological characteristics of pilomatricomas on multi-detector computed tomography (MDCT) and magnetic resonance imaging (MRI), and to correlate the radiological findings and pathological features.

Materials And Methods: The radiological findings of 41 pilomatricomas in 31 patients were retrospectively reviewed. The images were evaluated with emphasis on calcifications, reticular and ring-like appearances, enhancement patterns, circular target sign and peritumoral fat stranding, and correlating these with pathological features. Read More

BMJ Case Rep 2018 Aug 1;2018. Epub 2018 Aug 1.

General Internal Medicine, Tsukuba University, Mito, Japan.

J Dermatol 2018 Nov 21;45(11):e292-e293. Epub 2018 May 21.

Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan.

An Pediatr (Barc) 2019 Feb 13;90(2):126-127. Epub 2018 Apr 13.

Pediatría, Centro de Salud de San Sadurniño, SERGAS, San Sadurniño, A Coruña, España.

Dermatol Online J 2017 Dec 15;23(12). Epub 2017 Dec 15.

New York University Health, New York.

Anetoderma is a rare benign elastolytic disorder that is characterized by focal loss of elastin fibers on histopathology and is often recalcitrant to treatment. We present a case of a patient with a 20-year history of pruritic and painful hyperpigmented atrophic papules clustered on the neck, axillae, inframammary folds, and right medial thigh. Although the histopathologyof her axillary lesions was consistent with anetoderma, her clinical presentation is unusual given the extent of involvement, reported pain and pruritus, and sharp demarcation of the distribution. Read More

J Dtsch Dermatol Ges 2018 Feb;16(2):183-191

Department of Dermatology, Venereology, and Allergology, HELIOS Medical Center Hildesheim, Hildesheim, Germany.

Along with collagen, elastic fibers are integral components of cutaneous connective tissue. A decrease in elastic fibers or loss thereof has been described in a number of clinically distinct skin diseases, both hereditary and acquired. In disorders associated with inflammation, elastophagocytosis is an important histological hallmark. Read More

J Dtsch Dermatol Ges 2018 May 29;16(5):640-643. Epub 2018 Jan 29.

Department of Dermatology, Venereology and Allergology, University Medical Center Schleswig-Holstein, Kiel, Germany.

J Cutan Pathol 2017 Sep 5;44(9):786-789. Epub 2017 Jul 5.

Electron Microscopy, EMBRAPA-CPA-CT, Pelotas, Brazil.

Anetoderma is a rare cutaneous disorder characterized by focal loss of dermal elastic tissue due to unknown mechanisms. Primary anetoderma develops on clinical normal skin, without any preceding dermatosis and it can be associated with autoimmune conditions. Secondary anetoderma develops on the same area of a previous disorder, such as infectious, neoplastic or inflammatory diseases. Read More

Br J Dermatol 2017 06;176(6):e120

Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Int J STD AIDS 2017 12 1;28(14):1456-1460. Epub 2017 Jun 1.

4 Private Practice in São Paulo, São Paulo, Brazil.

Anetoderma is a rare benign condition of diverse etiology whose characteristic is the diminution or absence of the dermal elastic fibers. Classified as primary and secondary, the latter associated with tumors, inflammatory, and infectious diseases. Although the etiology of the lesions is well described in literature, the pathogenesis is still poorly determined. Read More

Br J Dermatol 2017 Oct 8;177(4):1127-1130. Epub 2017 Sep 8.

Dermatology Department, Nancy University Hospital, Vandoeuvre-les-Nancy, France.

Acrodermatitis chronica atrophicans (ACA) is the late cutaneous form of Lyme borreliosis. The early inflammatory phase manifests with a bluish-red discoloration and doughy swelling of the skin. The atrophic phase represents a late-phase process with red discoloration, and a thin and wrinkled appearance of the skin. Read More

Reumatol Clin 2018 Jul - Aug;14(4):242-243. Epub 2017 Mar 28.

Facultad de Medicina, Unidad de Patología Centro, Universidad de Chile, Las Condes, Santiago de Chile, Chile.

Dermatol Online J 2017 Mar 15;23(3). Epub 2017 Mar 15.

Hospital Universitario de Cabueñes, Servicio de Dermatología, Gijón, Asturias, España.

Pilomatricoma is a benign cutaneous tumor originatingfrom hair matrix cells. Anetodermic changes inthe skin overlying pilomatricomas are sometimesreported, although their precise mechanisms remainunknown. We present an unusual case of anetodermicpilomatricoma on the upper extremity of a 17-yearoldboy and report its clinical, histopathologic, andsonographic findings. Read More

Dermatol Online J 2017 Mar 15;23(3). Epub 2017 Mar 15.

Harvard Medical School, Boston, MA, USA. fandi_xia@ hms.harvard.edu.

Introduction: Anetoderma is an elastolytic skindisorder that has been associated with the presenceof antiphospholipid antibodies (aPL). Patients withantiphospholipid antibody-positive anetoderma havebeen reported to develop symptoms of Graves disease,antiphospholipid syndrome, and other autoimmuneconditions. The temporal relationship, however,between anetoderma onset and the emergence ofaPL remains unclear, a clarification of which may haveimplications for the screening and monitoring ofpatients with anetoderma. Read More

Clin Med (Lond) 2017 Feb;17(1):40-42

National University Health System, Singapore and Yong Loo Lin School of Medicine, National University Singapore, Singapore.

A 58-year-old Chinese woman with well controlled type 1 diabetes mellitus presented with acute and progressive bilateral lower limb weakness. Investigations revealed severe hypokalaemia (1.3 mmol/L) and hypophosphataemia (<0. Read More

J Immunol Res 2016 28;2016:4325463. Epub 2016 Dec 28.

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

. The clinical and histopathologic classification of anetoderma are not well characterized. . Read More

G Ital Dermatol Venereol 2016 Oct;151(5):566-9

Department of Dermatology and Venereology, Ege University Faculty of Medicine, Izmir, Turkey -

JAMA Dermatol 2016 11;152(11):1239-1243

Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.

Importance: Infantile hemangiomas involute to some extent, but they often leave sequelae that may cause disfigurement. Factors determining the risk of permanent sequelae after regression are of crucial importance in treatment decision making.

Objectives: To describe the sequelae left by infantile hemangiomas after natural involution and to identify clinical characteristics that could predict the most severe or a particular type of sequelae. Read More

Zhonghua Zheng Xing Wai Ke Za Zhi 2016 May;32(3):166-70

Objective: To investigate a simple, minimally invasive and effective operative method for the facial rejuvenation in the upper eyelid and midface region.

Methods: Blepharoplasty was combined with suspending orbicularis oculi muscle flap and fixing it on the periosteum underneath the eyebrow through eyebrow incision. Meanwhile, for midface rejuvenation, inferior palpebral margin incision was performed and prezygomatic interspace was separated completely under the orbicularis oculi muscle. Read More

Indian J Lepr 2016 04;88(2):129-131

Elastophagocytosis is the engulfment of the elastic fibres by the histiocytes, multinucleated giant cells, or both. The cutaneous lesions showing elastophagocytosis are annular elastolytic giant cell granuloma, actinic keratoses, persistent insect-bite reactions, elastosis perforans serpiginosa, foreign body granuloma. Occasionally, it may occur in infectious diseases like leprosy, granulomatous syphilis, North-American blastomycosis, bacterial folliculitis, and cutaneous leishmaniasis. Read More

Med Clin (Barc) 2016 Oct 5;147(8):e47. Epub 2016 Mar 5.

Servicio de Dermatología, Hospital Universitario Doce de Octubre, Madrid, España.

Int J Dermatol 2016 Jul 5;55(7):739-44. Epub 2016 Mar 5.

Kempf und Pfaltz Histologische Diagnostik, Research Unit, Zurich, Switzerland.

Patients with a lymphoma have an increased risk of developing a second lymphoproliferative disorder. The association of nodal Hodgkin lymphoma and primary cutaneous marginal zone lymphoma (MALT type) is exceptional, and only very few cases have been documented. Anetoderma represents a circumscribed loss or rarefication of elastic fibers. Read More

Acta Derm Venereol 2016 08;96(6):828-9

Unit of Dermatology, University of Padua, Via C. Battisti 206, IT-35128 Padova, Italy.

Acta Derm Venereol 2016 06;96(5):708-10

Department of Dermatology, Venereology and Allergology, Ruhr University Bochum, Gudrunstr. 56, DE-44791 Bochum, Germany.

G Ital Dermatol Venereol 2016 Feb 18;151(1):130-1. Epub 2015 Nov 18.

Section of Dermatology and Venereology, Departmen of Surgery and Translational Medicine, P. Palagi Hospital, University of Florence, School of Health Sciences, Florence, Italy.

Ann Dermatol Venereol 2015 Nov 3;142(11):716-8. Epub 2015 Sep 3.

Service de dermatologie et vénéreologie, CHU Ibn Sina, université Mohammed V, 6, immeuble 60, résidence Al Boustane, Souissi, Rabat, Maroc.

Aesthetic Plast Surg 2015 Dec 26;39(6):968-70. Epub 2015 Aug 26.

Vascular Anomalies Program of Lenox Hill Hospital, 210 East 64th Street - 7th Floor, New York, NY, 10065, USA.

Unlabelled: I was asked to provide a commentary for "Shouldn't Propranolol be Used to Treat All Hemangiomas?" by Moodley et al. (Aesth Plast Surg, 2015. doi: 10. Read More

Am J Med Genet A 2015 Oct 8;167A(10):2459-62. Epub 2015 Jun 8.

Department of Dermatology, University of Iowa Hospitals and Clinics.

Terminal osseous dysplasia with pigmentary defects (TODPD) is a rare, X-linked syndrome classically characterized by distal limb anomalies, pigmented skin defects of the face, and recurrent digital fibromas. X-inactivation plays a major role in determining the range of phenotypic expression. Thus, patients can demonstrate a wide spectrum of disease severity, making accurate diagnosis more challenging. Read More

J Cosmet Laser Ther 2016 3;18(1):38-40. Epub 2015 Jul 3.

a Dermatology and Cutaneous Biology, Jefferson University Hospitals , Philadelphia , PA , USA.

Anetoderma is a skin disorder characterized by a focal loss of dermal elastic tissue whereby patients present with soft, depressible lesions. We postulated that a series of combination treatment using the 595-nm pulsed dye laser (PDL) and the 1550-nm non-ablative fractionated laser (NAFL) would improve the anetoderma lesions. Our patient with biopsy proven anetoderma received 3 treatments with a combination of 595-nm PDL and 1550-nm NAFL spaced 3 weeks apart. Read More

J Cutan Pathol 2015 Oct 4;42(10):765-8. Epub 2015 Jun 4.

Department of Dermatology and Dermatopathology, Cleveland Clinic, Cleveland, OH, USA.

Anetoderma is a cutaneous disorder characterized by loss of dermal elastic tissue resulting in papules from herniation of subcutaneous tissue or circumscribed areas of atrophic, wrinkled skin. Familial leiomyomatosis cutis et uteri (Reed syndrome) is an autosomal dominant disorder characterized by cutaneous and uterine leiomyomas. We report a 23-year-old male with Reed syndrome who presented with asymptomatic pearly white, atrophic, flaccid papules on the upper back and shoulder that depressed when palpated. Read More

Eur J Dermatol 2015 May-Jun;25(3):277-9

CHU Dupuytren, 2 Avenue Martin Luther King, 87042 Limoges, France.