26,031 results match your criteria Anesthesiology[Journal]

Routine point-of-care ultrasound (POCUS) assessment of gastric antral content in traumatic emergency surgical patients for prevention of aspiration pneumonitis: an observational clinical trial.

BMC Anesthesiol 2021 May 8;21(1):140. Epub 2021 May 8.

Anesthesia and Intensive Care, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Background: Polytrauma patients are at a higher risk of delayed gastric emptying. To assess the gastric volume, a reliable diagnostic tool is needed to prevent the occurrence of aspiration pneumonia, which remains a serious complication associated with anesthesia. Gastric antral ultrasound can provide reliable information about the size of the gastric antrum in traumatized patients undergoing emergency surgery. Read More

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The effect of dexmedetomidine on intraoperative blood glucose homeostasis: secondary analysis of a randomized controlled trial.

BMC Anesthesiol 2021 May 7;21(1):139. Epub 2021 May 7.

Department of Anesthesiology, Peking University First Hospital, Beijing, China.

Purpose: To investigate the effect of dexmedetomidine on intraoperative blood glucose hemostasis in elderly patients undergoing non-cardiac major surgery.

Methods: This was secondary analysis of a randomized controlled trial. Patients in dexmedetomidine group received a loading dose dexmedetomidine (0. Read More

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Comparison of transversus abdominis plane catheters with thoracic epidurals for cost and length of stay in open colorectal surgeries: a cohort study.

BMC Anesthesiol 2021 May 6;21(1):137. Epub 2021 May 6.

Department of Anesthesiology, Albany Medical Center, 43 New Scotland Avenue, Albany, NY, USA.

Background: Thoracic epidural analgesia has long been a common method of postoperative analgesia for major open abdominal surgeries and is frequently used within enhanced recovery after surgery programs. An alternative postoperative analgesia method is the single shot transversus abdominis plane block, which has shown promising outcomes with respect to total length of stay, cost, pain scores, and decreased opioid usage. However, far less is known regarding continuous transversus abdominis plane analgesia using catheters. Read More

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Can perioperative hemodilution be monitored with non-invasive measurement of blood hemoglobin?

BMC Anesthesiol 2021 May 6;21(1):138. Epub 2021 May 6.

Department of Anesthesiology and Intensive Care, and Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.

Background: Trends in non-invasive measurements of blood hemoglobin (Hb) may be useful for identifying the need for transfusion in the perioperative period.

Methods: Crystalloid fluid (5-20 mL/kg) was administered intravenously or by mouth to 30 volunteers and 33 surgical patients in five non-randomized clinical studies where Hb was measured on 915 occasions by non-invasive (Radical-7™) and invasive methodology. The hemodilution curves were compared by volume kinetic analysis and linear regression, with the slope and scattering of the data as key outcome measures. Read More

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Isoflurane Suppresses Hippocampal High-frequency Ripples by Differentially Modulating Pyramidal Neurons and Interneurons in Mice.

Anesthesiology 2021 May 5. Epub 2021 May 5.

Background: Isoflurane can induce anterograde amnesia. Hippocampal ripples are high-frequency oscillatory events occurring in the local field potentials of cornu ammonis 1 involved in memory processes. The authors hypothesized that isoflurane suppresses hippocampal ripples at a subanesthetic concentration by modulating the excitability of cornu ammonis 1 neurons. Read More

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Computer-assisted Individualized Hemodynamic Management Reduces Intraoperative Hypotension in Intermediate- and High-risk Surgery: A Randomized Controlled Trial.

Anesthesiology 2021 May 5. Epub 2021 May 5.

Background: Individualized hemodynamic management during surgery relies on accurate titration of vasopressors and fluids. In this context, computer systems have been developed to assist anesthesia providers in delivering these interventions. This study tested the hypothesis that computer-assisted individualized hemodynamic management could reduce intraoperative hypotension in patients undergoing intermediate- to high-risk surgery. Read More

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Comparison of remifentanil concentrations with and without dexmedetomidine for the prevention of emergence cough after nasal surgery: a randomized double-blinded trial.

BMC Anesthesiol 2021 May 4;21(1):136. Epub 2021 May 4.

Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, 164, World cup-ro, Yeongtong-gu, Suwon, 16499, South Korea.

Background: Preventing emergence cough after nasal surgery is critical. Emergence cough can provoke immediate postoperative bleeding, which leads to upper airway obstruction. In the present study, we compared the effect-site concentration (Ce) of remifentanil to prevent emergence cough after propofol anesthesia for nasal surgery when remifentanil was or was not combined with dexmedetomidine. Read More

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Mild increases in plasma creatinine after intermediate to high-risk abdominal surgery are associated with long-term renal injury.

BMC Anesthesiol 2021 Apr 30;21(1):135. Epub 2021 Apr 30.

Department of Anesthesiology, Brugmann Hospital, Université Libre de Bruxelles, 4, Place A. Van Gehuchten, 1020 Bruxelles, Bruxelles, Belgium.

Background: The potential relationship between a mild acute kidney injury (AKI) observed in the immediate postoperative period after major surgery and its effect on long term renal function remains poorly defined. According to the "Kidney Disease: Improving Global Outcomes" (KDIGO) classification, a mild injury corresponds to a KIDIGO stage 1, characterized by an increase in creatinine of at least 0.3 mg/dl within a 48-h window or 1. Read More

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Echo in Atrial Flutter.

Anesthesiology 2021 Apr 30. Epub 2021 Apr 30.

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Automated Nerve Monitoring in Shoulder Arthroplasty: A Prospective Randomized Controlled Study.

Anesthesiology 2021 Apr 30. Epub 2021 Apr 30.

Background: Evoked potential monitoring is believed to prevent neurologic injury in various surgical settings; however, its clinical effect has not been scrutinized. It was hypothesized that an automated nerve monitor can minimize intraoperative nerve injury and thereby improve clinical outcomes in patients undergoing shoulder arthroplasty.

Methods: A prospective, blinded, parallel group, superiority design, single-center, randomized controlled study was conducted. Read More

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Prophylactic temporary abdominal aortic balloon occlusion for patients with pernicious placenta previa: a retrospective study.

BMC Anesthesiol 2021 Apr 29;21(1):134. Epub 2021 Apr 29.

Department of Anesthesiology, Peking University People's Hospital, Beijing, 100044, China.

Background: Pernicious placenta previa (PPP) can increase the risk of perioperative complications. During caesarean section in patients with adherent placenta, intraoperative blood loss, hysterectomy rate and transfusion could be reduced by interventional methods. Our study aimed to investigate the influence of maternal hemodynamics control and neonatal outcomes of prophylactic temporary abdominal aortic balloon (PTAAB) occlusion for patients with pernicious placenta previa. Read More

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My Neatest Handwriting.

John A Guzzi

Anesthesiology 2021 Apr 29. Epub 2021 Apr 29.

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Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling.

Anesthesiology 2021 Apr 29. Epub 2021 Apr 29.

Background: Sepsis is one of the leading causes of mortality in intensive care units, and sedation in the intensive care unit during sepsis is usually performed intravenously. The inhalative anesthetic sevoflurane has been shown to elicit protective effects in various inflammatory studies, but its role in peritonitis-induced sepsis remains elusive. The hypothesis was that sevoflurane controls the neutrophil infiltration by stabilization of hypoxia-inducible factor 1α and elevated adenosine A2B receptor expression. Read More

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Labor epidural analgesia versus without labor epidural analgesia for multiparous women: a retrospective case control study.

BMC Anesthesiol 2021 Apr 28;21(1):133. Epub 2021 Apr 28.

Department of Gynaecology and Obstetrics, Shandong Province Maternal and Child Health Care Hospital, 238 East Road of Jingshi, Jinan, Shandong, P.R. China.

Background: Labor epidural analgesia (LEA) effectively relieves the labor pain, but it is still not available consistently for multiparous women in many institutions because of their obviously shortened labor length.

Methods: A total of 811 multiprous women were retrospective enrolled and firstly divided into two groups: LEA group or non-LEA group. And then they were divided into seven subgroups and analyzed according to the use of LEA and cervical dilation. Read More

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A Crack at MAC.

Anesthesiology 2021 Apr 28. Epub 2021 Apr 28.

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Mitochondrial Function and Anesthetic Sensitivity in the Mouse Spinal Cord.

Anesthesiology 2021 Apr 28. Epub 2021 Apr 28.

Background: Ndufs4 knockout (KO) mice are defective in mitochondrial complex I function and hypersensitive to inhibition of spinal cord-mediated response to noxious stimuli by volatile anesthetics. It was hypothesized that, compared to wild-type, synaptic or intrinsic neuronal function is hypersensitive to isoflurane in spinal cord slices from knockout mice.

Methods: Neurons from slices of the vestibular nucleus, central medial thalamus, and spinal cord from wild-type and the global Ndufs4 knockout were patch clamped. Read More

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A randomized controlled trial of ultrasound-assisted technique versus conventional puncture method for saphenous venous cannulations in children with congenital heart disease.

BMC Anesthesiol 2021 Apr 27;21(1):131. Epub 2021 Apr 27.

Department of Anesthesiology, Shanghai Children's Medical Center Affiliated to School of Medicine, Shanghai Jiao Tong University, 1678 Dongfang Road, Pudong, Shanghai, 200127, China.

Background: The study investigated the success rate of the great saphenous venous catheter placement performed by ultrasound-assisted technique compared with the conventional puncture method in infants and toddlers with congenital heart disease and aimed to assess the efficiency and feasibility of this method within the context of pediatric peripheral venous access.

Methods: We selected infants and toddlers who underwent congenital cardiac surgery in our medical center from June 1, 2020, to September 7, 2020, by convenience sampling. Children were stratified by the presence of the manifesting cardiac types (cyanotic or acyanotic heart disease). Read More

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Modified STOP-Bang for predicting perioperative adverse events in the Thai population.

BMC Anesthesiol 2021 Apr 27;21(1):132. Epub 2021 Apr 27.

270 Department of Anesthesiology, Faculty of Medicine, Ramathibodi hospital, Mahidol University, Rama VI road, Phayathai, Ratchatewi, Bangkok, 10400, Thailand.

Background: Undiagnosed obstructive sleep apnea (OSA) is associated with adverse perioperative outcomes. The STOP-Bang questionnaire is a validated screening tool for OSA. However, its precision may vary among different populations. Read More

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Spinal subdural hematoma and subdural anesthesia following combined spinal-epidural anesthesia: a case report.

BMC Anesthesiol 2021 Apr 26;21(1):130. Epub 2021 Apr 26.

Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Sichuan Province, Chengdu, China.

Background: Subdural anesthesia and spinal subdural hematoma are rare complications of combined spinal-epidural anesthesia. We present a patient who developed both after multiple attempts to achieve combined spinal-epidural anesthesia.

Case Presentation: A 21-year-old parturient, gravida 1, para 1, with twin pregnancy at gestational age 34 weeks underwent cesarean delivery. Read More

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Assisted Fluid Management Software Guidance for Intraoperative Fluid Administration.

Anesthesiology 2021 Apr 26. Epub 2021 Apr 26.

Background: Excessive or inadequate fluid administration causes complications, but despite this, fluid administration during noncardiac surgery is highly variable. Goal-directed management helps optimize the amount and timing of fluid administration; however, implementation is difficult because algorithms are complex. The authors therefore tested the performance of the Acumen Assisted Fluid Management software (Edwards Lifesciences, USA), which is designed to guide optimal intravenous fluid administration during surgery. Read More

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