346,495 results match your criteria Anesthesia essays and researches[Journal]


Intraoperative monitoring of olfactory function: a feasibility study.

J Neurosurg 2019 Apr 19:1-6. Epub 2019 Apr 19.

2Faculty of Medicine, University of Geneva, Switzerland.

OBJECTIVEIntraoperative neuromonitoring of the chemical senses (smell and taste) has never been performed. The objective of this study was to determine if olfactory-evoked potentials could be obtained intraoperatively under general anesthesia.METHODSA standard olfactometer was used in the surgical theater with hydrogen sulfide (4 ppm, 200 msec). Read More

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https://thejns.org/view/journals/j-neurosurg/aop/article-10.
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http://dx.doi.org/10.3171/2019.1.JNS182731DOI Listing
April 2019
1 Read

MicroRNA-181b-5p attenuates early postoperative cognitive dysfunction by suppressing hippocampal neuroinflammation in mice.

Cytokine 2019 Apr 16;120:41-53. Epub 2019 Apr 16.

Department of Anesthesiology, Zhongnan Hospital of Wuhan University, 169 Donghu Road, Wuhan, Hubei, China. Electronic address:

Background: Postoperative cognitive dysfunction (POCD) is a common complication after surgery and its occurrence is associated with increased morbidity and mortality. However, the pathophysiology of this complication remains largely unknown. Efforts to identify causes of POCD have focused on the hippocampal neuroinflammation. Read More

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http://dx.doi.org/10.1016/j.cyto.2019.04.005DOI Listing

Chronic cerebral hypoperfusion-induced memory impairment and hippocampal long-term potentiation deficits are improved by cholinergic stimulation in rats.

Pharmacol Rep 2019 Jan 30;71(3):443-448. Epub 2019 Jan 30.

Centre for Drug Research, Universiti Sains Malaysia, Penang, Malaysia. Electronic address:

Background: Chronic cerebral hypoperfusion (CCH) can induce the accumulation of reactive oxygen species, which leads to oxidative damage, neuronal injury, and central cholinergic dysfunction in vulnerable regions of the brain, such as the hippocampus and cerebral cortex. These effects can lead to significant cognitive impairments in clinical populations of vascular dementia (VaD). The present studies aimed to investigate the role of the cholinergic system in memory functions and hippocampal long-term potentiation (LTP) impairments induced by CCH in rats. Read More

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http://dx.doi.org/10.1016/j.pharep.2019.01.012DOI Listing
January 2019

Nurse anesthetists' preferences for anesthesiologists' participation in patient care at a large teaching hospital.

J Clin Anesth 2019 Apr 16;57:131-138. Epub 2019 Apr 16.

Department of Anesthesia, University of Iowa, United States of America.

Study Objective: Certified registered nurse anesthetists (CRNAs) can evaluate anesthesiologists with whom they work clinically using a psychometrically reliable and valid scale. Use of such a scale to evaluate performance depends on knowing thresholds for minimum and ideal anesthesiologist performance.

Design: Cohort study. Read More

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http://dx.doi.org/10.1016/j.jclinane.2019.04.018DOI Listing

Patient Satisfaction with Oral Versus Intravenous Sedation for Cataract Surgery : A Randomized Clinical Trial.

Ophthalmology 2019 Apr 16. Epub 2019 Apr 16.

Department of Ophthalmology, Boston Medical Center, Boston University School of Medicine, Boston, MA.

Purpose: To determine whether patient satisfaction with oral sedation is non-inferior to intravenous (IV) sedation for cataract surgery.

Design: A prospective, randomized, double-masked clinical trial.

Subjects: A volunteer sample of patients age 18 or older from diverse ethnic, racial, and socioeconomic backgrounds scheduled for cataract surgery. Read More

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http://dx.doi.org/10.1016/j.ophtha.2019.04.022DOI Listing

Fluid management in acute kidney injury.

Chest 2019 Apr 16. Epub 2019 Apr 16.

Division of Nephrology & Hypertension, Division of Pulmonary & Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, US.

Correction of intravascular hypovolaemia is a key component of the prevention and management of acute kidney injury (AKI) but excessive fluid administration is associated with poor outcomes, including the development and progression of AKI. There is growing evidence that fluid administration should be individualised and take into account patient characteristics, nature of the acute illness and trajectories, and risks and benefits of fluids. Existing data support the preferential use of buffered solutions for fluid resuscitation of patients at risk of AKI who do not have hypochloraemia. Read More

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http://dx.doi.org/10.1016/j.chest.2019.04.004DOI Listing

Normothermic Machine Perfusion in Liver Transplantation: Avoiding Recooling Before Engrafting Is Feasible and Promising.

Liver Transpl 2019 Apr 19. Epub 2019 Apr 19.

Abdominal Surgery and Organ Transplantation Unit, Department for the Treatment and Study of Abdominal Diseases and Abdominal Transplantation, IRCCS-ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione), Palermo, Italy.

It is well known that ischemia and the reperfusion process are distinct nonimmunological events that negatively impact graft outcome and induce delayed graft function, which are associated with high rates of organ failure, retransplantation, and death. Cooling the organ slows metabolism but does not prevent its progressive dysfunction and destruction of cellular integrity. On the other hand, in the reperfusion phase, the reactive oxygen metabolites cause leukocyte accumulation and therefore increased microvascular permeability and cellular injury. Read More

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http://dx.doi.org/10.1002/lt.25473DOI Listing

Clinical findings associated with development of postoperative reflux and short-term survival after small intestinal surgery in geriatric and mature nongeriatric horses.

Vet Surg 2019 Apr 19. Epub 2019 Apr 19.

Department of Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania.

Objective: To determine risk factors, especially age, associated with postoperative reflux (POR; >2 L of reflux present upon intubation), high-volume POR (≥20 L in 24 hours), and short-term outcome after small intestinal (SI) surgery.

Study Design: Retrospective case-control study.

Sample Population: Horses aged ≥16 years (geriatric; range, 16-30; n = 44) and <16 years (mature; range, 2-15; n = 39) with an SI surgical lesion that survived general anesthesia and did not have a second exploratory celiotomy during the same visit. Read More

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http://dx.doi.org/10.1111/vsu.13217DOI Listing

Propofol may increase caspase and MAPK pathways, and suppress the Akt pathway to induce apoptosis in MA‑10 mouse Leydig tumor cells.

Oncol Rep 2019 Apr 18. Epub 2019 Apr 18.

Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan 70101, R.O.C.

In the western world, there is an increasing trend of occurrence in testicular cancer. Treatment of malignant testicular cancer is primarily combined surgery with various chemical drugs. Propofol has been frequently used as an anesthetic and sedative induction agent, which could modulate different γ‑aminobutyric acid receptors in the central nervous system. Read More

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http://dx.doi.org/10.3892/or.2019.7129DOI Listing

Feasibility of pulmonary valve imaging using transesophageal echocardiography upper esophageal view.

Echocardiography 2019 Apr 19. Epub 2019 Apr 19.

Division of Cardiology, University of Colorado School of Medicine, Aurora, Colorado.

Background: The present study designed to evaluate feasibility of transesophageal echocardiographic (TEE) imaging of the pulmonary valve (PV) at the transaortic upper esophageal (TAUE) window. We hypothesized that patients with larger aorta would be more likely to have visualization of the PV from this TAUE window.

Methods: 2D TEE images of the PV were prospectively acquired by one operator at the TAUE window looking through the aortic arch. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/echo.14332
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http://dx.doi.org/10.1111/echo.14332DOI Listing
April 2019
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Parallelism between risk and perception of risk among caregivers during anesthesia delivery.

Eur Rev Med Pharmacol Sci 2019 Apr;23(7):3129-3141

Department of Information Engineering, Electronics, and Telecommunications, Sapienza University of Rome, Rome, Italy.

The paper examines the different perceptions of risk associated with anesthesia systems from the viewpoint of the product manufacturer and the caregiver. Only a little research has been done with regard to the impact of perception of risk on patient safety in anesthesia. The role of the manufacturer in mitigating the perception of risk will be central for the work. Read More

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http://dx.doi.org/10.26355/eurrev_201904_17597DOI Listing

Evaluation of Propofol in Comparison with Other General Anesthetics for Surgery in Children Younger than 3 Years: a Systematic Review and Meta-Analysis.

J Korean Med Sci 2019 Apr 22;34(15):e124. Epub 2019 Apr 22.

Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.

Background: Despite well-known advantages, propofol remains off-label in many countries for general anesthesia in children under 3 years of age due to insufficient evidence regarding its use in this population. This study aimed to evaluate the efficacy and safety of propofol compared with other general anesthetics in children under 3 years of age undergoing surgery through a systematic review and meta-analysis of existing randomized clinical trials.

Methods: A comprehensive literature search was conducted of MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials to find all randomized clinical trials comparing propofol with another general anesthetic that included children under 3 years of age. Read More

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http://dx.doi.org/10.3346/jkms.2019.34.e124DOI Listing

Bronchial Thermoplasty in Patients with Severe Uncontrolled Asthma: First Korean Cases.

J Korean Med Sci 2019 Apr 22;34(15):e120. Epub 2019 Apr 22.

Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Bronchial thermoplasty is a nonpharmacological treatment for severe asthma that delivers thermal energy to the bronchial walls and reduces hypertrophied smooth muscle mass. Previous studies have shown its efficacy and safety, resulting in approval from the Food and Drug Administration in 2010. In Korea, the first bronchial thermoplasty was carried out in 2014; 4 patients have undergone the procedure so far. Read More

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https://jkms.org/DOIx.php?id=10.3346/jkms.2019.34.e120
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http://dx.doi.org/10.3346/jkms.2019.34.e120DOI Listing
April 2019
3 Reads

The effect of pediatric patient temperament on post-operative outcomes.

Paediatr Anaesth 2019 Apr 18. Epub 2019 Apr 18.

Boston Children's Hospital, Department of Anesthesiology, Perioperative and Pain Medicine, Boston, MA, 02115.

Background: Research has improved practitioner awareness of the impact of individual characteristics on responses to painful procedures. However, there is little data relating pre-existing temperament profiles and post-surgical/anesthesia outcomes in pediatric patients. In particular, it is not clear how best to identify which patients are at risk of poor post-surgical outcomes. Read More

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http://dx.doi.org/10.1111/pan.13646DOI Listing

A New Neural Pathway from the Ventral Striatum to the Nucleus Basalis of Meynert with Functional Implication to Learning and Memory.

Mol Neurobiol 2019 Apr 18. Epub 2019 Apr 18.

Department of Biomedical Science, Charles E. Schmidt College of Medicine, Florida Atlantic University, 777 Glades Road, Boca Raton, FL, 33431, USA.

The cholinergic neurons in the nucleus basalis of Meynert (NBM) are among the first group of neurons known to become degenerated in Alzheimer's disease, and thus the NBM is proposed to be involved in learning and memory. The marginal division (MrD) of the striatum is a newly discovered subdivision at the ventromedial border of the mammalian striatum and is considered to be one part of the ventral striatum involved in learning and memory. The present study provided evidence to support the hypothesis that the MrD and the NBM were structurally connected at cellular and subcellular levels with functional implications in learning and memory. Read More

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http://dx.doi.org/10.1007/s12035-019-1588-0DOI Listing

Alterations in the gustatory papillae after anterior bite plate insertion in growing rats.

J Orthod Sci 2019 20;8. Epub 2019 Feb 20.

Department of Orthodontic Science, Division of Oral Health Science, Graduate School, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

Objectives: To determine whether the modification of dental occlusion, without molar extraction, affected the gustatory papillae located in the tongue of growing rats.

Materials And Methods: Five-week-old male Wistar rats were randomly divided into an anterior bite plate (ABP) group and a control group. Under general anesthesia, ABPs were placed on the occlusal surfaces of the maxillary incisors, while metal caps covered the mandibular incisal edges of the rats in the ABP group. Read More

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http://www.jorthodsci.org/text.asp?2019/8/1/4/252616
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http://dx.doi.org/10.4103/jos.JOS_68_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416994PMC
February 2019
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Explainable machine-learning predictions for the prevention of hypoxaemia during surgery.

Nat Biomed Eng 2018 Oct 10;2(10):749-760. Epub 2018 Oct 10.

Paul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, WA, USA.

Although anaesthesiologists strive to avoid hypoxemia during surgery, reliably predicting future intraoperative hypoxemia is not currently possible. Here, we report the development and testing of a machine-learning-based system that, in real time during general anaesthesia, predicts the risk of hypoxemia and provides explanations of the risk factors. The system, which was trained on minute-by-minute data from the electronic medical records of over fifty thousand surgeries, improved the performance of anaesthesiologists when providing interpretable hypoxemia risks and contributing factors. Read More

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http://dx.doi.org/10.1038/s41551-018-0304-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467492PMC
October 2018

Lornoxicam with Low-Dose Ketamine versus Pethidine to Control Pain of Acute Renal Colic.

Pain Res Treat 2019 13;2019:3976027. Epub 2019 Mar 13.

Department of Anesthesia, ICU and Pain Management, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Objectives: This study was established to compare single-dose lornoxicam 8 mg (NSAID) in addition to 0.15 mg.kg ketamine with single-dose pethidine 50 mg, both administered intravenously (IV), on the quickness and extent of analgesia, disadvantage, and consequence on utilitarian situation. Read More

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http://dx.doi.org/10.1155/2019/3976027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436326PMC

Bilateral Bifid mandibular canals - Special relevance for a general dental practitioner. Report of 2 cases.

J Clin Exp Dent 2019 Mar 1;11(3):e287-e289. Epub 2019 Mar 1.

BDS. College of Medicine and Dentistry, James Cook University. Smithfield, Queensland - 4878. Australia.

Dental practitioners may encounter bifid mandibular canals upon radiographic assessment, and may not understand the true extent of this presentation. The presentation of a bifid mandibular canal poses difficulties when carrying out dental procedures, including administration of mandibular block anaesthesia, oral surgical procedures of the lower third molars, orthognathic surgery and implant placement. Therefore it is of paramount importance that general dental practitioners be aware of the radiographic appearance, as incorrect diagnosis of this rare presentation can lead to detrimental consequences. Read More

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http://dx.doi.org/10.4317/jced.55575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461729PMC

Characterization of the Asymmetry of the Cardiac and Sympathetic Arms of the Baroreflex From Spontaneous Variability During Incremental Head-Up Tilt.

Front Physiol 2019 2;10:342. Epub 2019 Apr 2.

Department of Cardiothoracic, Vascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato, Milan, Italy.

Hysteresis of the baroreflex (BR) is the result of the different BR sensitivity (BRS) when arterial pressure (AP) rises or falls. This phenomenon has been poorly studied and almost exclusively examined by applying pharmacological challenges and static approaches disregarding causal relations. This study inspects the asymmetry of the cardiac BR (cBR) and vascular sympathetic BR (sBR) in physiological closed loop conditions from spontaneous fluctuations of physiological variables, namely heart period (HP) and systolic AP (SAP) leading to the estimation of cardiac BRS (cBRS) and muscle sympathetic nerve activity (MSNA) and diastolic AP (DAP) leading to the estimation of vascular sympathetic BRS (sBRS). Read More

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http://dx.doi.org/10.3389/fphys.2019.00342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454064PMC

A Rare Case of Thoracic Subdural Hematoma after Recovery from Dengue Fever.

J Neurosci Rural Pract 2019 Apr-Jun;10(2):380-381

Department of Anaesthesia and Critical Care, Armed Forces Medical College, Pune, Maharashtra, India.

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http://www.ruralneuropractice.com/text.asp?2019/10/2/380/254
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http://dx.doi.org/10.4103/jnrp.jnrp_314_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454941PMC
April 2019
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Clinical presentation and outcome after anterior cervical discectomy and fusion for degenerative cervical disc disease.

J Craniovertebr Junction Spine 2019 Jan-Mar;10(1):28-32

Department of Neurosurgery, Narayana Medical College Hospital, Nellore, Andhra Pradesh, India.

Background: Anterior cervical discectomy and fusion (ACDF) is a well-described surgical approach for symptomatic degenerative cervical disc disease which does not respond to conservative management. In the present study, we assessed clinical presentation and outcomes of ACDF.

Materials And Methods: The present study was conducted from October 1, 2015, to October 31, 2017, in the Department of Neurosurgery, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, among 100 consecutive adult patients who underwent single- or two-level ACDF for degenerative cervical disc disease. Read More

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http://dx.doi.org/10.4103/jcvjs.JCVJS_87_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469327PMC

Unilateral giant internal jugular vein - In response.

Indian J Anaesth 2019 Apr;63(4):331-332

Department of Anaesthesia and Intensive Care, PGIMER, Chandigarh, India.

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http://dx.doi.org/10.4103/ija.IJA_223_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460985PMC

Giant internal jugular vein.

Indian J Anaesth 2019 Apr;63(4):329-330

Department of Anaesthesia and Perioperative Medicine, Royal Brisbane and Women's Hospital and The University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.4103/ija.IJA_59_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460973PMC

Ultrasound-guided left brachiocephalic vein cannulation: Where to puncture the vein?

Indian J Anaesth 2019 Apr;63(4):327-328

Department of Anaesthesia, All India Institute of Medical Sciences, Patna, Bihar, India.

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http://www.ijaweb.org/text.asp?2019/63/4/327/255466
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http://dx.doi.org/10.4103/ija.IJA_801_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460984PMC
April 2019
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Continuous spinal anaesthesia for caesarean section in a patient with peripartum cardiomyopathy.

Indian J Anaesth 2019 Apr;63(4):317-319

Department of Anaesthesiology and Critical Care, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana, Punjab, India.

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http://www.ijaweb.org/text.asp?2019/63/4/317/255459
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http://dx.doi.org/10.4103/ija.IJA_769_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460981PMC
April 2019
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Anaesthetic management of an infant with tracheomalacia scheduled for computed tomography angiography: A challenge.

Indian J Anaesth 2019 Apr;63(4):312-315

Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India.

Tracheomalacia is characterised by collapse of the tracheal wall with respiration. Computed tomography angiography (CTA) can be utilised for evaluation of airway abnormalities but providing sedation/anaesthesia for CTA in such a case carries the risk of airway catastrophe. We describe the anaesthetic management of an infant who had tracheomalacia with >90% collapse in lower two third of the intrathoracic trachea as diagnosed on videobronchoscpy and was scheduled for CTA. Read More

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http://www.ijaweb.org/text.asp?2019/63/4/312/255468
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http://dx.doi.org/10.4103/ija.IJA_874_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460980PMC
April 2019
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A new indication of erector spinae plane block for perioperative analgesia is total hip replacement surgery - A case report.

Indian J Anaesth 2019 Apr;63(4):310-311

Department of Anaesthesia, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.

A new indication of ultrasound - guided Erector spinae plane block for perioperative analgesia is orthopaedic surgery. We report here the use of this paraspinal block in the case of a 68-yr-old female with multiple systemic disorder for total hip replacement surgery. Read More

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http://dx.doi.org/10.4103/ija.IJA_25_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460971PMC

Magnesium sulphate optimises surgical field without attenuation of the stapaedius reflex in paediatric cochlear implant surgery.

Indian J Anaesth 2019 Apr;63(4):304-309

Software Test Engineer, MED-EL Medical Electronics, Cairo, Egypt.

Background And Aims: The anaesthesia technique for paediatric cochlear implantation should be modified to achieve an optimised surgical field and allow neuromonitoring. Total intravenous anaesthesia (TIVA) provides good surgical condition without affecting intraoperative electrical stapaedial reflex threshold (ESRT). Though magnesium sulphate (MgSO) is a cheap, readily available drug for controlled hypotension, it can decrease the amplitude of motor-evoked potentials. Read More

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http://dx.doi.org/10.4103/ija.IJA_754_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460987PMC

Comparing the efficacy of aprepitant and ondansetron for the prevention of postoperative nausea and vomiting (PONV): A double blinded, randomised control trial in patients undergoing breast and thyroid surgeries.

Indian J Anaesth 2019 Apr;63(4):289-294

Department of Anesthesia, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

Background And Aims: Aprepitant, a Neurokinin-1 receptor antagonist, has been evaluated in abdominal and neurosurgeries, but its effect is less clear in breast and thyroid surgeries, which are also known to be high risk for post-operative nausea and vomiting (PONV). This study was done to compare the antiemetic efficacy of ondansetron and aprepitant in women undergoing mastectomy and thyroidectomy.

Methods: One hundred and twenty-five ASA I and II, female patients, aged between 18 and 65 years were randomly assigned into Group I (ondansetron group, = 62) or Group II (aprepitant group, = 63), by computer-generated random sequencing. Read More

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http://dx.doi.org/10.4103/ija.IJA_724_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460978PMC
April 2019
1 Read

Correlation between bispectral index, end-tidal anaesthetic gas concentration and difference in inspired-end-tidal oxygen concentration as measures of anaesthetic depth in paediatric patients posted for short surgical procedures.

Indian J Anaesth 2019 Apr;63(4):277-283

Department of Paediatric Anaesthesiology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.

Background And Aims: Measurement of end-tidal anaesthetic gas concentrations (ETAG) is currently a pragmatic indicator for monitoring anaesthetic depth. We aimed to assess the performance of ETAG for sevoflurane (ETAG-sevo) with bispectral index (BIS) and difference between inspired and end-tidal oxygen concentration (Fi-Et)O% in measuring anaesthetic depth in toddlers and preschool children. Primary outcome was to correlate BIS with ETAG-sevo. Read More

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http://dx.doi.org/10.4103/ija.IJA_653_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460983PMC

Reliability of the thyromental height test for prediction of difficult visualisation of the larynx: A prospective external validation.

Indian J Anaesth 2019 Apr;63(4):270-276

Department of Anesthesiology, Tohoku Kosai Hospital, 2-3-11 Kokubun-cho, Aoba-ku, Sendai, Japan.

Background And Aims: Thyromental height (TMH) has been reported to be useful for prediction of difficult visualisation of the larynx (DVL), defined as Cormack--Lehane (C&L) grade III or IV. The aim of this study was to compare the diagnostic accuracy of the TMH test for DVL with that of other clinically used tests in Japanese patients.

Methods: Six hundred and nine surgical patients undergoing endotracheal intubation under general anaesthesia were enrolled in this prospective observational study. Read More

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http://dx.doi.org/10.4103/ija.IJA_852_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460976PMC

Radiological evaluation of airway - What an anaesthesiologist needs to know!

Indian J Anaesth 2019 Apr;63(4):257-264

Department of Oncoanaesthesia and Palliative Medicine, Dr. BRAIRCH AIIMS, New Delhi, India.

Airway management forms the foundation of any anaesthetic management. However, unanticipated difficult airway (DA) and its sequelae continue to dread any anaesthesiologist. In spite of development of various clinical parameters to judge DA, no single parameter has proved to be accurate in predicting it. Read More

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http://dx.doi.org/10.4103/ija.IJA_488_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460969PMC

Antimicrobial consumption and bacterial resistance pattern in patients admitted in I.C.U at a tertiary care center.

J Infect Public Health 2019 Apr 16. Epub 2019 Apr 16.

Department of Anesthesia, Lady Hardinge Medical College, New Delhi, India.

Background: Throughout the world multi drug resistant nosocomial infections are one of the leading causes of death and morbidity among hospitalized patients. Antimicrobial resistance [AMR] has become a major problem in treatment of such infections. High consumption of antimicrobials particularly in ICUs is often described as the most important factor leading to AMR. Read More

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http://dx.doi.org/10.1016/j.jiph.2019.03.014DOI Listing

Early-Onset Ventilator-Associated Pneumonia in Severe Traumatic Brain Injury: is There a Relationship with Prehospital Airway Management?

J Emerg Med 2019 Apr 15. Epub 2019 Apr 15.

Division of Anesthesia, Intensive Care, and Prehospital Emergency, Maggiore Hospital Carlo Alberto Pizzardi, Bologna, Italy.

Background: Prehospital airway management in severe traumatic brain injury (TBI) is widely recommended by international guidelines for the management of trauma. Early-onset ventilator-associated pneumonia (EOVAP) is a common occurrence in this population and can worsen mortality and functional outcome.

Objectives: In this retrospective observational study, we aimed to evaluate the association between different prehospital airway management variables and the occurrence of EOVAP. Read More

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http://dx.doi.org/10.1016/j.jemermed.2019.02.005DOI Listing

Acute and subsequent continuation electroconvulsive therapy elevates serum BDNF levels in patients with major depression.

Brain Stimul 2019 Feb 26. Epub 2019 Feb 26.

Department of Psychiatry and Psychotherapy, Medical University of Vienna, 1090, Vienna, Waehringerstr 18-20, Austria. Electronic address:

Introduction: The induction of brain-derived neurotrophic factor (BDNF) release and subsequent restoration of neuroplastic homeostasis may underlie the effects of electroconvulsive therapy (ECT).

Objectives: We aimed to assess serum and plasma BDNF levels during the course of acute ECT, as well as before and after subsequent continuation ECT, in patients with depression.

Methods: We included 24 patients with major depressive disorder (mean age ± SD: 54. Read More

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http://dx.doi.org/10.1016/j.brs.2019.02.015DOI Listing
February 2019

MRI-guided frame-based stereotactic brainstem biopsy procedure: A single-center experience.

Neurocirugia (Astur) 2019 Apr 15. Epub 2019 Apr 15.

Department of Neurosurgery, Kent Hospital, İzmir, Turkey.

Introduction And Objectives: This study aims at presenting our experience of the MRI-guided frame-based stereotactic brainstem biopsy method, and evaluating the outcomes of the procedure.

Patients And Methods: The current study involved 18 cases that underwent MRI-guided frame-based stereotactic biopsy for brainstem lesions between 2011 and 2018 in our clinic. The relevant data regarding the technique of the biopsy procedure, morbidity, histopathological diagnosis it yields and diagnostic accuracy was retrospectively analyzed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S11301473193002
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http://dx.doi.org/10.1016/j.neucir.2019.03.001DOI Listing
April 2019
1 Read

Current status of rheumatic heart disease in India.

Indian Heart J 2019 Jan - Feb;71(1):85-90. Epub 2019 Jan 4.

Department of Anaesthesia, IGMC Shimla, India.

The rheumatic heart disease continues to be an important cause of disease burden in India, affecting the population in their prime and productive phase of the life. The prevalence of rheumatic heart disease is varied in different Indian studies, because of the inclusion of different populations at different point of times and using different screening methods for the diagnosis. The data on incidence and prevalence on a nationally represented sample are lacking. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00194832183054
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http://dx.doi.org/10.1016/j.ihj.2018.12.007DOI Listing
January 2019
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An advanced junction concept in pediatric craniospinal irradiation by proton pencil beam scanning.

Phys Med 2019 Apr 9;60:168-173. Epub 2019 Apr 9.

From Proton Therapy Center, Hospital of Trento, Azienda Provinciale per I Servizi Sanitari (APSS), Trento 38122, Italy. Electronic address:

Purpose: To present an advanced junction concept in craniospinal irradiation (CSI) by proton pencil beam scanning (PBS).

Materials And Methods: In PBS CSI, whole brain irradiation (WBI) is commonly delivered by opposed lateral-beams, whereas spine irradiation is delivered by posterior entrances. Since lateral-beams would cross a large portion of the patient at the shoulder level, the junction between WBI and spine irradiation cannot extend below that level, thus the size of the lateral-beams needs to be limited and the number of required isocenters can increase. Read More

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http://dx.doi.org/10.1016/j.ejmp.2019.04.002DOI Listing

Pushing the limits: perinatal outcomes beyond prolonged second stage.

J Matern Fetal Neonatal Med 2019 Apr 18:1-211. Epub 2019 Apr 18.

d Alexandria Health , Boston , USA.

Objective: To evaluate whether extremely prolonged second stage of labor in nulliparous women affects mode of delivery and perinatal outcomes.

Methods: We performed a retrospective cohort study of nulliparous women with singleton gestations and cephalic presentation who reached 10 cm of cervical dilation at gestational age 36 0/7-41 6/7. Women were stratified by epidural status. Read More

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http://dx.doi.org/10.1080/14767058.2019.1609927DOI Listing

Perceived Neighborhood Environment and Its Association with Health Screening and Exercise Participation amongst Low-Income Public Rental Flat Residents in Singapore.

Int J Environ Res Public Health 2019 Apr 17;16(8). Epub 2019 Apr 17.

Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore 117549, Singapore.

: In Singapore, an Asian city-state, more than 80% live in public housing. While the majority (90%) own their homes, a needy minority lives in rental flats. Public rental flats are built in the same location as owner-occupied blocks. Read More

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https://www.mdpi.com/1660-4601/16/8/1384
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http://dx.doi.org/10.3390/ijerph16081384DOI Listing
April 2019
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A comparison of three techniques for cricothyrotomy on a manikin.

Can J Respir Ther 2017 1;53(2):29-32. Epub 2017 May 1.

Department of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Victoria General Hospital, 1276 South Park St. Halifax Nova Scotia, Canada.

Background: Cricothyrotomy can either be performed by an "open" cricothyrotomy technique, or by a needle (Seldinger) technique. Clinical uncertainty exists regarding which technique is more effective. We compared three different techniques for cricothyrotomy, performed by anesthesiologists on a manikin. Read More

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[Pain and distress responses of suckling piglets to injection and castration under local anaesthesia with procaine and lidocaine - Part 1: Cortisol, chromogranin A, wound healing, weights, losses].

Tierarztl Prax Ausg G Grosstiere Nutztiere 2019 Apr 18;47(2):87-96. Epub 2019 Apr 18.

Klinik für Schweine der Ludwig-Maximilians-Universität München.

Objective: Comparison of the effectiveness of local anaesthesia (LA) in piglet castration by procaine 2 % and lidocaine 5 % both through combined inguinal and scrotal application as well as by intratesticular application of lidocaine 1 %. The parameters used were serum cortisol and chromogranin A (CgA) concentrations as well as wound healing, body weight and animal losses.

Material And Methods: In 2 substudies, a total of 232 male piglets aged 3-6 days were included. Read More

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http://dx.doi.org/10.1055/a-0861-9640DOI Listing

Cost-benefit analysis of the use of tranexamic acid in total replacement hip surgery.

J Clin Anesth 2019 Apr 15;57:124-128. Epub 2019 Apr 15.

Office of Health Economics, London, UK.

Study Objective: To establish the best dose regimen for tranexamic acid (TXA) in total hip replacement surgery.

Design: Secondary analysis based on data from a multicenter double-blind randomized clinical trial.

Setting: Two hospitals in Spain. Read More

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http://dx.doi.org/10.1016/j.jclinane.2019.04.006DOI Listing

Prediction of uncuffed tracheal tube sizes in children and infants using age/weight-based formulae: A retrospective cross-sectional study.

Int J Pediatr Otorhinolaryngol 2019 Apr 12;122:105-110. Epub 2019 Apr 12.

Epidemiology Unit, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, 90110, Thailand.

Introduction: The age-based formula is commonly used to predict tracheal tube (TT) sizes although its inaccuracy has been reported to reach as high as 60%. We aim to determine a practical formula using age in months and weight in kilograms to predict uncuffed tracheal tube (TT) size in children and infants.

Methods: A retrospective cross-sectional study was conducted on data obtained from a prospective study on children aged less than 9 years who came for elective surgery and received general anesthesia with oroendotracheal tube intubation at Songklanagarind Hospital between September 2008 and December 2012. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.04.011DOI Listing

Perioperative management of a patient with severe factor V deficiency presenting with chronic subdural hematoma: a clinical report.

World Neurosurg 2019 Apr 15. Epub 2019 Apr 15.

Department of Anaesthesiology University Hospital of Munich (LMU) Marchioninistraße 15 81377 Munich Germany.

Background: Severe factor V deficiency is an extremely rare coagulation disorder. Patients with factor V activity below 5% usually become symptomatic in early childhood.

Methods: We report the case of an 82 year old woman with incidentally diagnosed severe factor V deficiency, who developed a symptomatic chronic subdural hematoma, requiring burr-hole craniostomy. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.04.080DOI Listing

Reply to Dr Sanz and Dr. del Valle about Predatory publishing in Palliative Care.

J Pain Symptom Manage 2019 Apr 15. Epub 2019 Apr 15.

Department of Surgical, Oncological and Oral Science (Di.Chir.On.S.). Section of Anesthesia, Analgesia, Intensive Care and Emergency. Policlinico Paolo Giaccone. University of Palermo, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S08853924193017
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http://dx.doi.org/10.1016/j.jpainsymman.2019.04.004DOI Listing
April 2019
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