340,709 results match your criteria Anesthesia and analgesia[Journal]


Identification and Modulation of Microenvironment is Crucial for Effective MSC Therapy in Acute Lung Injury.

Am J Respir Crit Care Med 2018 Dec 6. Epub 2018 Dec 6.

The State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China, Critical Care Medicine, Guangzhou, Guangdong, China.

Rationale: There are controversial reports on applications of mesenchymal stromal cells (MSCs) in patients with acute respiratory distress syndrome (ARDS).

Objective: We hypothesized that lung microenvironment was the main determinant of beneficial versus detrimental effects of MSCs during ARDS.

Methods: Lung proteome was profiled in three models of injury induced by acid instillation and/or mechanical ventilation in mice. Read More

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December 2018
2 Reads

Pre-emptive and preventive opioids for postoperative pain in adults undergoing all types of surgery.

Cochrane Database Syst Rev 2018 Dec 3;12:CD012624. Epub 2018 Dec 3.

Department of Surgery and Anaesthesia, Division of Medical Sciences and Graduate Entry Medicine, School of Medicine, University of Nottingham, Uttoxeter New Road, Derby, UK, DE22 3DT.

Background: Postoperative pain is a common consequence of surgery and can have deleterious effects. It has been suggested that the administration of opioid analgesia before a painful stimulus may improve pain control. This can be done in two ways. Read More

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December 2018
3 Reads

Identification of factors during bronchoscopy that affect patient reluctance to undergo repeat examination: Questionnaire analysis after initial bronchoscopy.

PLoS One 2018 6;13(12):e0208495. Epub 2018 Dec 6.

Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.

Background: Re-biopsy by bronchoscopy is an important part of treatment for patients with relapsed lung cancer; however, some patients refuse to undergo a re-examination due to discomfort during their first bronchoscopy. The aim of the present study was to determine factors causing discomfort during bronchoscopy and to identify the factors that affect patients' reluctance to undergo repeat examinations via a questionnaire administered immediately after the initial bronchoscopy.

Methods And Findings: We evaluated 283 patients who underwent bronchoscopy at Chiba University Hospital between September 2015 and March 2017. Read More

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December 2018
1 Read

Patient-reported outcomes associated with different restorative techniques in pediatric dentistry: A systematic review and MTC meta-analysis.

PLoS One 2018 6;13(12):e0208437. Epub 2018 Dec 6.

Department of Pediatric Dentistry and Orthodontics, Faculty of Dentistry, University of São Paulo, São Paulo, São Paulo, Brazil.

Background: Despite the increasing number of studies evaluating patient reported outcome measures (PROs), there is no clearness regarding which restorative treatment offers major benefits based on the pediatric patient perspective.

Aim: To compare different restorative techniques in pediatric dentistry regarding patient-reported outcomes.

Design: Literature searching was carried out on prospective studies indexed in PubMed, Scopus and OpenGrey. Read More

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December 2018
1 Read

The effect of net gas volume changes on alveolar and arterial gas partial pressures in the presence of ventilation-perfusion mismatch.

J Appl Physiol (1985) 2018 Dec 6. Epub 2018 Dec 6.

Department of Anaesthesia, Austin Hospital, Australia.

The second gas effect (SGE) occurs when nitrous oxide enhances the uptake of volatile anesthetics administered simultaneously. Recent work shows that the SGE is greater in blood than in the gas phase, that this is due to ventilation-perfusion mismatch, that as mismatch increases, the SGE increases in blood but is diminished in the gas phase, and that these effects persist well into the period of nitrous oxide maintenance anesthesia. These modifications of the SGE are most pronounced with the low soluble agents in current use. Read More

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December 2018

Does the experience of the bedside assistant effect the results of robotic surgeons in the learning curve of robot assisted radical prostatectomy?

Int Braz J Urol 2018 Oct 20;44. Epub 2018 Oct 20.

American Hospital, Istanbul, Turkey.

Introduction: The success of the robot assisted radical prostatectomy (RARP) procedures depend on a successful team, however the literature focuses on the performance of a console surgeon. The aim of this study was to evaluate surgical outcomes of the surgeons during the learning curve in relation to the bedside assistant's experience level during RARP.

Materials And Methods: We retrospectively reviewed two non - laparoscopic, beginner robotic surgeon's cases, and we divided the patients into two groups. Read More

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October 2018
2 Reads

Laparoscopic approach for intravesical surgery using pneumovesicum in the management of anterior colporrhaphy mesh erosion and stones around the bladder neck.

Int Braz J Urol 2018 Sep 20;44. Epub 2018 Sep 20.

Department of Urology, Korea University Ansan Hospital, Korea University College of Medicine, Korea.

Introduction And Objective: Perforation of the bladder or urethra and erosion of the mesh after cystocele repair surgery are not uncommon and have potentially serious complications. Traditionally, surgical management of such complications has involved excision of the mesh using either a transurethral approach or open surgery. In this video, we present our experience of laparoscopic transvesical surgery for exposed mesh and stone. Read More

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September 2018

Incidence of adverse events attributable to bupivacaine liposome injectable suspension or plain bupivacaine for postoperative pain in pediatric surgical patients: a retrospective matched cohort analysis.

Paediatr Anaesth 2018 Dec 6. Epub 2018 Dec 6.

Departments of Outcomes Research, Cleveland Clinic, Cleveland, Ohio, United States.

Background: Surgical wound infiltration with local anesthetics is common as part of multimodal analgesia and enhanced recovery pathways in pediatric surgical patients. Liposomal bupivacaine can provide up to 92 hours of pain relief, and was approved by the U.S Food and Drug Administration for local infiltration in adults. Read More

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December 2018
1 Read

Polygenic risk score identifies associations between sleep duration and diseases determined from an electronic medical record biobank.

Sleep 2018 Dec 5. Epub 2018 Dec 5.

Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA USA.

Study Objectives: We aimed to detect cross-sectional phenotype and polygenic risk score (PRS) associations between sleep duration and prevalent diseases using the Partners Biobank, a hospital-based cohort study linking electronic medical record (EMR) with genetic information.

Methods: Disease prevalence was determined from EMR, and sleep duration was self-reported. A PRS for sleep duration was derived using 78 previously associated SNPs from GWAS for self-reported sleep duration. Read More

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December 2018

Using Simulation to Teach Echocardiography: A Systematic Review.

Simul Healthc 2018 Dec;13(6):413-419

From the Department of Medicine, University of Florida, College of Medicine (C.A.R., J.M.M.), University of Florida Health Science Center Libraries (H.F.N.); Division of Medical Education, Department of Pediatrics (E.B.), Division of Cardiovascular Medicine, Department of Medicine (D.E.W.), University of Florida, College of Medicine, Gainesville, FL.

Statement: We identified 24 studies of high-fidelity simulation being used to teach echocardiography. A variety of study designs were used with outcomes ranging from reports of learner self-confidence up to improvement in organizational practice. Most studies were carried out in graduate medical populations, specifically in anesthesia trainees. Read More

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December 2018

Reply to: cerebral oximetry monitoring. To guide physiology, avert catastrophe or both?

Eur J Anaesthesiol 2019 Jan;36(1):83

From the Department of Anaesthesia, General Hospital, Hospital Universitario Virgen del Rocío, Sevilla, Spain (MdlM, AD).

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January 2019

Reply to: prediction of bilateral cerebral oxygen desaturation from a single sensor in adult cardiac surgery.

Eur J Anaesthesiol 2019 Jan;36(1):81-82

From the Department of Anaesthesia, Hospital General, Hospital Universitario Virgen del Rocío (MdlM, AD) and Statistics, Methodology and Research Evaluation Unit, Andalusian Public Foundation for Health Research Management (JMP), Sevilla, Spain.

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January 2019

Reply to: fluid therapy for critical haemorrhage during elective noncardiac surgery.

Eur J Anaesthesiol 2019 Jan;36(1):79-80

From the Anaesthesia Department, Hospital Universitari Bellvitge, Universidad de Barcelona (MJC) and Anaesthesia Department, Hospital Universitario Vall d'Hebron, Universidad Autónoma de Barcelona, Barcelona, Spain (PG).

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January 2019

Reply to: fluid therapy for critical haemorrhage during elective noncardiac surgery.

Eur J Anaesthesiol 2019 Jan;36(1):78-79

From the Department of Anaesthesiology, CHU Brugmann, Brussels, Belgium (PVdL), Department of Anaesthesiology, Surgical Intensive Care and Pain Medicine, St.-Elisabeth-Hospital Straubing, Straubing, Germany (MJ), and Department of Anaesthesia and Intensive Care, Evangelical Hospital Vienna and Sigmund Freud Private University, Vienna, Austria (SK).

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January 2019

Continuous haemodynamic effects of left tilting and supine positions during Caesarean section under spinal anaesthesia with a noninvasive cardiac output monitor system.

Eur J Anaesthesiol 2019 Jan;36(1):72-75

From the Department of Anaesthesiology (S-ET, PHY, PKH, SLT), Epidemiology and Biostatistics Centre (Y-JC) and Department of Anaesthesiology, Changhua Christian Hospital, Changhua City, Changhua County, Taiwan (YJH).

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January 2019

Uterine tilt for caesarean section.

Eur J Anaesthesiol 2019 Jan;36(1):6-7

From the Department of Anaesthesia and Critical Care, University Hospitals of Wuerzburg, Wuerzburg, Germany (GL, PK).

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January 2019

Anesthesia Quality Improvement on Both Sides of the Atlantic.

Int Anesthesiol Clin 2019 ;57(1):131-143

Nuffield Department of Anaesthetics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

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January 2019

Scaling Perioperative Services Across Health Care Systems.

Int Anesthesiol Clin 2019 ;57(1):1-17

Department of Anesthesia, Critical Care and Pain Medicine, Perioperative Services, Massachusetts General Hospital, Boston, Massachusetts, USA.

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January 2019

Impaired Hypoxic Pulmonary Vasoconstriction in a Mouse Model of Leigh Syndrome.

Am J Physiol Lung Cell Mol Physiol 2018 Dec 6. Epub 2018 Dec 6.

Department of Anesthesia, Massachusetts General Hospital, United States.

Hypoxic pulmonary vasoconstriction (HPV) is a physiological vasomotor response that maintains systemic oxygenation by matching perfusion to ventilation during alveolar hypoxia. Although mitochondria appear to play an essential role in HPV, the impact of mitochondrial dysfunction on HPV remains incompletely defined. Mice lacking the mitochondrial complex I (CI) subunit Ndufs4 (Ndufs4-/-) develop a fatal progressive encephalopathy and serve as a model for Leigh syndrome, the most common mitochondrial disease in children. Read More

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December 2018

The effectiveness of scoring systems in the prediction of diagnosis-based mortality.

Ther Apher Dial 2018 Dec 6. Epub 2018 Dec 6.

Department of Anaesthesiology, University of Healthy Sciences, Bakırkoy Dr. Sadi Konuk Training and Research Hospital Istanbul, Turkey.

Scoring systems are used for mortality and morbidity rating in intensive care conditions, prognosis prediction, standardization of scientific data and the monitoring of clinical quality. The aim of this study was to retrospectively analyze the efficacy of APACHE II (Acute Physiology and Chronic Health Evaluation), APACHE IV and SAPS (Simplified Acute Physiology Score) III prognostic scorings in the prediction of mortality and disease severity of patients admitted to the Anesthesia and Reanimation Clinic Intensive Care Unit (ICU) in Bakırköy Dr. Sadi Konuk Training and Research Hospital according to general and specific diagnoses. Read More

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December 2018

Perceptions and experiences of patients following treatment with single-implant mandibular overdentures: a qualitative study.

Clin Oral Implants Res 2018 Dec 5. Epub 2018 Dec 5.

School of Dentistry, Federal University of Goias, Goiania, Goias, Brazil.

Objective: This study aimed to explore the perceptions and long-term experiences of edentulous patients rehabilitated with single-implant mandibular overdentures (SIMO).

Methods: Thirteen participants, mean age 65.7 years, 69. Read More

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December 2018

Anaphylaxis to intravenous gelatin-based solutions: a case series examining clinical features and severity.

Anaesthesia 2018 Dec 5. Epub 2018 Dec 5.

Department of Anaesthesia and Peri-operative Medicine, Monash University, Melbourne, Vic., Australia.

The proportion of patients receiving intravenous gelatin-based colloids has increased in the last decade due to safety concerns about starch-based products. Recent research suggests hypersensitivity reactions to intravenous gelatin-based solutions occur at similar rates per administration as non-depolarising neuromuscular blocking agents such as rocuronium (6.2/100,000 administrations). Read More

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December 2018
2 Reads

Adductor canal block with a suture-method catheter - A parallel or perpendicular approach?

Acta Anaesthesiol Scand 2018 Dec 6. Epub 2018 Dec 6.

Department of Anaesthesia and Intensive Care Medicine, Copenhagen University Hospital, Nordsjaellands Hospital, Hillerød, Denmark.

Background: We performed a randomised blinded pilot study in 16 healthy volunteers to assess whether placing a suture-method catheter in the adductor canal is feasible with two different insertion techniques.

Methods: Each volunteer had a suture-method catheter placed approximately halfway between the superior anterior iliac spine and base of the patella in both legs. Catheters were placed using a parallel technique in one leg and a perpendicular technique in the other leg, according to randomisation. Read More

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December 2018
3 Reads

Supplemental oxygen and hyperoxemia in trauma patients: A prospective, observational study.

Acta Anaesthesiol Scand 2018 Dec 6. Epub 2018 Dec 6.

Department of Anesthesia, Section 4231, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Background: Supplemental oxygen is recommended during the initial treatment of trauma patients according to several guidelines, but the supporting evidence is sparse. We aimed to describe the use of supplemental oxygen and occurrence of hyperoxemia in the initial phase of trauma management at two level 1 trauma centers, TC1 and TC2.

Methods: In this prospective, observational study we included trauma patients ≥16 years of age. Read More

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December 2018

Efficacy of external cold and a vibrating device in reducing discomfort of dental injections in children: A split mouth randomised crossover study.

Eur Arch Paediatr Dent 2018 Dec 5. Epub 2018 Dec 5.

Department of Paediatric Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia.

Aim: To study the discomfort and fear associated with maxillary infiltration injections when using a combination of external cold and a commercially available vibrating device.

Methodology: A total of 60 children aged 7 years old participated in this split mouth randomised crossover study. The control intervention comprised of the administration of 1. Read More

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December 2018
1 Read

Oxygen reserve index (ORi™) contributes to prediction of hypoxemia and patient safety during tracheal stent insertion using rigid bronchoscopy: a case report.

J Clin Monit Comput 2018 Dec 5. Epub 2018 Dec 5.

Department of Anesthesiology and Critical Care Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-Shi, Tochigi-Ken, 329-0498, Japan.

The oxygen reserve index (ORi™) is a new noninvasive and continuous variable, which represents a moderate hyperoxygenation status, with a unitless scale between 0.00 and 1.00. Read More

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December 2018

[Cheek-midface lift for revision following failed excessive lower eyelid blepharoplasty].

Ophthalmologe 2018 Dec 5. Epub 2018 Dec 5.

Zentrum für Augenheilkunde, Universitätsklinikum Köln, Kerpener Str. 62, 50937, Köln, Deutschland.

Iatrogenic ectropion with sagging of the lower eyelid after failed excessive lower eyelid blepharoplasty is a severe complication in aesthetic surgery. Traditionally, free skin grafting is the method of choice for correction. This overview presents the cheek-midface lift as a useful and powerful method for the correction of ectropion following excessive lower eyelid blepharoplasty. Read More

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December 2018
1 Read

How Bispectral Index Compares to Spectral Entropy of the EEG and A-line ARX Index in the Same Patient.

Open Med (Wars) 2018 24;13:583-596. Epub 2018 Nov 24.

Department of Anaesthesia and Intensive Care Medicine, Innsbruck Medical University, A-6020 Innsbruck, Anichstrasse 35, Innsbruck Austria.

Background: Bispectral index (BIS) monitoring of depth of anesthesia has pioneered the field for more recent monitoring devices like the A-line ARX Index (AAI) or the state (SE) and response entropy (RE) monitoring devices. Following an observational design the present study aimed to simultaneously compare in the same patient recorded BIS, AAI and entropy values.

Methods: Data from patients (n = 32) undergoing minor gynecological operations were analyzed. Read More

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November 2018

Impact of Intravenous Fluid Challenge Infusion Time on Macrocirculation and Endothelial Glycocalyx in Surgical and Critically Ill Patients.

Biomed Res Int 2018 1;2018:8925345. Epub 2018 Nov 1.

Dpt. of Anesthesiology and Intensive Care Medicine, Faculty of Medicine in Plzen, Charles University, Plzen, Czech Republic.

The fluid challenge (FC) is a well-established test of preload reserve. Only limited data exist in regard to the FC efficacy based on infusion time. Slow administration may be associated with lack of effect based on fluid redistribution and external conditions changes. Read More

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November 2018

Comparison of Effects of Light Anesthetics, Diethyl Ether and Carbon Dioxide, on Hypothalamic Paraventricular Nucleus D and D Dopamine Receptors- and Glucosensitive Neurons-Induced Food Intake in Fasted Conscious Rats.

Basic Clin Neurosci 2018 Jul-Aug;9(4):269-274. Epub 2018 Jul 1.

Neurophysiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Introduction: Carbon Dioxide (CO) and diethyl ether are used as light anesthetics. However, experimental data about their side effects are scarce. In addition, in all our previous works on regulatory mechanisms of hypothalamus during food intake, including the effect of Paraventricular Nucleus (PVN) D and D dopamine receptors and glucosensitive neurons, the drug injections were performed under brief diethyl ether anesthesia. Read More

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Effects of fascia iliaca compartment block combined with general laryngeal mask airway anesthesia in children undergoing femoral fracture surgery: a randomized trial.

J Pain Res 2018 8;11:2821-2826. Epub 2018 Nov 8.

School of Medicine, Jiaxing University, Jiaxing 314000, Zhejiang, China,

Background: Postoperative agitation after general anesthesia is a common complication in children; however, pain or uncomfortable feeling is the main reason of emergence agitation. Here, we have investigated the effects of fascia iliaca compartment block (FICB) combined with general laryngeal mask airway (LMA) anesthesia in children undergoing femoral surgery.

Methods: Eighty children undergoing femoral surgery were randomly divided into two groups: FICB + LMA group and control group (n=40). Read More

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November 2018

ED of intrathecal ropivacaine for cesarean delivery with and without epidural volume extension with normal saline: a randomized controlled study.

Authors:
M Lv P Zhang Z Wang

J Pain Res 2018 8;11:2791-2796. Epub 2018 Nov 8.

Institute of Clinical Research, Jiaxing university, Jiaxing, China,

Background: It was reported that epidural volume extension could decrease the ED of intrathecal plain bupivacaine. In this study, we investigated the ED of intrathecal hyperbaric ropivacaine followed by epidural normal saline bolus for cesarean section.

Methods: Sixty parturients were allocated into two groups in this prospective study. Read More

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November 2018

Gender, genetics, and analgesia: understanding the differences in response to pain relief.

J Pain Res 2018 8;11:2729-2739. Epub 2018 Nov 8.

Department of Anesthesia, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA,

Genetic variations and gender contribute significantly to the large interpatient variations in opioid-related serious adverse effects and differences in pain relief with other analgesics. Opioids are the most commonly used analgesics to relieve moderate-to-severe postoperative pain. Narrow therapeutic index and unexplained large interpatient variations in opioid-related serious adverse effects and analgesia negatively affect optimal perioperative outcomes. Read More

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November 2018

Postoperative cognitive dysfunction - current preventive strategies.

Clin Interv Aging 2018 8;13:2267-2273. Epub 2018 Nov 8.

Department of Surgery, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.

Improving trends in global health care have resulted in a steady increase in the geriatric population. However, as the population ages, surgery is being performed more frequently in progressively older patients and those with higher prevalence of comorbidities. A significant percentage of elderly patients experience transient postoperative delirium following surgery or long-term postoperative cognitive dysfunction (POCD). Read More

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November 2018

Supraglottic airway devices for surfactant treatment: systematic review and meta-analysis.

J Perinatol 2018 Dec 5. Epub 2018 Dec 5.

Department of Woman's and Child's Health, University of Padova, Padova, Italy.

Objective: To compare surfactant administration via supraglottic airway device (SAD) vs. nasal CPAP alone or INSURE.

Study Design: A systematic search of PubMed, EMBASE, SCOPUS, Cochrane Central Register of Controlled Trials and Clinicaltrials. Read More

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December 2018
1 Read

A phase I trial of low-dose inhaled carbon monoxide in sepsis-induced ARDS.

JCI Insight 2018 Dec 6;3(23). Epub 2018 Dec 6.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.

Background: Acute respiratory distress syndrome (ARDS) is a prevalent disease with significant mortality for which no effective pharmacologic therapy exists. Low-dose inhaled carbon monoxide (iCO) confers cytoprotection in preclinical models of sepsis and ARDS.

Methods: We conducted a phase I dose escalation trial to assess feasibility and safety of low-dose iCO administration in patients with sepsis-induced ARDS. Read More

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December 2018

Effect of regional versus general anaesthesia on postoperative delirium in elderly patients undergoing surgery for hip fracture: a systematic review.

BMJ Open 2018 Dec 4;8(12):e020757. Epub 2018 Dec 4.

Warwick Medical School, University of Warwick, Coventry, UK.

Objective: Older patients with hip fractures who are undergoing surgery are at high risk of significant mortality and morbidity including postoperative delirium. It is unclear whether different types of anaesthesia may reduce the incidence of postoperative delirium. This systematic review will investigate the impact of anaesthetic technique on postoperative delirium. Read More

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December 2018

Adult With Mutation and Late-Onset Congenital Central Hypoventilation Syndrome.

J Clin Sleep Med 2018 Nov 29. Epub 2018 Nov 29.

Abstract: 20/27 polyalanine repeat mutation (PARM) in patients with congenital central hypoventilation syndrome (CCHS) is generally associated with full-time ventilator dependence, Hirschsprung disease, and increased risk for cardiac asystole. We follow a 14-year-old boy with CCHS 20/27 PARM who is full-time ventilator dependent via tracheostomy and has Hirschsprung disease. His mother, age 52 years, has a history of prolonged recovery from anesthesia and an elevated serum bicarbonate level of 45 mEq/L discovered on routine blood chemistry. Read More

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November 2018

Using operating room turnover time by anesthesia trainee level to assess improving systems-based practice milestones.

BMC Med Educ 2018 Dec 5;18(1):295. Epub 2018 Dec 5.

Houston Methodist Hospital, Houston, TX, USA.

Background: Operating room (OR) metrics are frequently cited when optimizing cost efficacy and quality of care (Weiss et al, Characteristics of operating room procedures in U.S. hospitals, 2011: Statistical brief #170, 2013; Macario A, Anesthesiology 105:237-240, 2006; Childers et al, JAMA Surg 153:e176233, 2018). Read More

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December 2018
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Trajectories of early secondary insults correlate to outcomes of traumatic brain injury: results from a large, single centre, observational study.

BMC Emerg Med 2018 Dec 5;18(1):52. Epub 2018 Dec 5.

School of Medicine and Surgery, University of Milan-Bicocca, Via Cadore 48, 20900, Monza, MB, Italy.

Background: Secondary insults (SI), such as hypotension, hypoxia, and intracranial hypertension frequently occur after traumatic brain injury (TBI), and have a strong impact on patients' clinical outcomes. The aim of this study is to examine the trajectories of SI from the early phase of injury in the prehospital setting to hospital admission in a cohort of TBI patients.

Methods: This is a retrospective, observational, single centre study on consecutive patients admitted from 1997 to 2016 to the Neuro Intensive Care Unit (NICU) at San Gerardo Hospital, in Monza, Italy. Read More

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December 2018

Correlation Between ROTEM FIBTEM Maximum Clot Firmness and Fibrinogen Levels in Pediatric Cardiac Surgery Patients.

Clin Appl Thromb Hemost 2018 Dec 5:1076029618816382. Epub 2018 Dec 5.

3 The Heart Program, Nicklaus Children's Hospital, Miami, FL, USA.

This study evaluated whether rotational thromboelastometry (ROTEM; Tem International GmbH, Munich, Germany) FIBTEM maximum clot firmness (MCF) can be used to predict plasma fibrinogen level in pediatric patients undergoing cardiac surgery. Linear regression was conducted to predict plasma fibrinogen level using FIBTEM MCF (0.05 level of significance). Read More

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December 2018

[Botulinumtoxin for bladder disorders].

Fortschr Neurol Psychiatr 2018 Dec 3. Epub 2018 Dec 3.

Marien Hospital Herne, Universitätsklinikum der Ruhr- Universität Bochum, Abteilung für Neuro-Urologie.

An overactive neurogenic detrusor and an non-neurogenic overactive bladder both exhibit symptoms such as urgency and frequency, both with and without urinary incontinence, and are often accompanied by nocturia. OnabotulinumtoxinA-Detrusorinjection has become well established as a second line therapy in cases where anticholinergic medication has failed. The procedure can be performed under general or local anesthesia, in both in- and outpatient settings. Read More

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December 2018
2 Reads

Administration of the benzodiazepine midazolam increases tau phosphorylation in the mouse brain.

Neurobiol Aging 2018 Nov 8;75:11-24. Epub 2018 Nov 8.

Département de Psychiatrie et Neurosciences, Faculté de Médecine, Université Laval, Québec City, Québec, Canada; CRCHU, CHUL, Neurosciences, Québec City, Québec, Canada.

Preclinical studies have shown that anesthesia might accelerate the clinical progression of Alzheimer's disease (AD) and can have an impact on tau pathology, a hallmark of AD. Although benzodiazepines have been suggested to increase the risk of incident dementia, their impact on tau pathology in vivo is unknown. We thus examined the impact of midazolam, a benzodiazepine that is often administered perioperatively as an anxiolytic, on tau hyperphosphorylation in nontransgenic and in hTau mice, the latter a model of AD-like tau pathology. Read More

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November 2018

Ambulation with Femoral Arterial Cannulation Can be Safely Performed on Veno-Arterial Extracorporeal Membrane Oxygenation.

Ann Thorac Surg 2018 Nov 30. Epub 2018 Nov 30.

Department of Cardiothoracic Surgery, New York University Langone Health.

Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support can be associated with significant deconditioning due to the requirement for strict bedrest as a result of femoral arterial cannulation. In order to address this issue, we evaluated our experience with ambulation in patients with peripheral femoral cannulation for VA-ECMO.

Methods: All patients that were peripherally cannulated for VA-ECMO over a two year period were retrospectively reviewed. Read More

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November 2018

Do you believe that processed EEG helps to prevent intraoperative awareness?

Authors:
Dong Woo Han

Korean J Anesthesiol 2018 Dec 30;71(6):427-429. Epub 2018 Nov 30.

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

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December 2018
1 Read

Nonintubated surgical biopsy of undetermined interstitial lung disease: a multicentre outcome analysis.

Interact Cardiovasc Thorac Surg 2018 Dec 1. Epub 2018 Dec 1.

Section of Biostatistics, Tor Vergata University, Rome, Italy.

Objectives: Nonintubated surgical biopsy (NISB) of interstitial lung disease (ILD) has shown promise in unicentre reports as a reliable method to achieve pathological diagnosis with low morbidity. The aim of this study was to investigate for the first time early outcomes of NISB of ILD using a multicentre retrospective analysis.

Methods: Seven European and extra-European institutions participated in the study. Read More

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December 2018
1 Read