5,650 results match your criteria Anesthesia Topical


Cataract Surgery Practice in the Republic of Korea: A Survey of the Korean Society of Cataract and Refractive Surgery 2020.

Korean J Ophthalmol 2021 Jun 21. Epub 2021 Jun 21.

Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.

Purpose: To describe current cataract surgery practice patterns and trends among Korean ophthalmologists.

Methods: A survey was conducted among members of the Korean Society of Cataract and Refractive Surgery (KSCRS) in October 2020. Of the 998 questionnaires, 262 (26. Read More

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The Role of Topical Anesthetics in the Treatment of Pediatric Facial Lacerations.

J Oral Maxillofac Surg 2021 May 23. Epub 2021 May 23.

Department of Oral and Maxillofacial Surgery, University Hospitals Sussex NHS Foundation Trust, St. Richard's Hospital, Worthing, United Kingdom.

Purpose: Pediatric facial lacerations (PLACS) are a common emergency, often requiring a general anesthetic (GA) or sedation if infiltration of local anesthetic (LA) cannot be tolerated. Topical anesthetics are a well-established and accepted alternative to infiltrations for facial lacerations which can reduce the need for general anesthesia. We report our experience following the introduction of topical 5% cocaine w/v and 1:2,000 adrenaline gel (TCA) in a single center. Read More

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Combined methyl aminolevulinate-based photodynamic therapy and imiquimod in a patient with perianal extramammary Paget's disease.

Photodiagnosis Photodyn Ther 2021 Jun 16:102407. Epub 2021 Jun 16.

Skin Institute, Hualian Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan; Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan. Electronic address:

Extramammary Paget's disease (EMPD) is a rare form of intraepithelial adenocarcinoma. Complete surgical removal of localized disease is the treatment of choice for EMPD but carries anaesthesia-related risks and possible postoperative functional deficits. Herein, we present a case of perianal EMPD successfully treated with topical methyl aminolevulinate-based photodynamic therapy (MAL-PDT), followed by topical imiquimod. Read More

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Normal intraocular pressure in Egyptian children and meta-analysis.

Eye (Lond) 2021 Jun 18. Epub 2021 Jun 18.

Ophthalmic Department, Cairo University, Cairo, Egypt.

Objective: To determine the normal intraocular pressure in a sample of Egyptian children 0-12 years of age, and compare it to that recorded in previous studies.

Methods: This is a prospective cross-sectional study, including 345 eyes. All children underwent complete history taking and ophthalmic examination. Read More

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Comparison of thiopentone with lidocaine spray vs propofol for laryngeal mask airway insertion at tikur anbessa specialized hospital. A prospective cohort study.

Ann Med Surg (Lond) 2021 Jun 2;66:102436. Epub 2021 Jun 2.

Addis Ababa University, College of Medicine and Health Science, Department of Anesthesia, Addis Ababa, Ethiopia.

Background: Insertion of laryngeal mask airway (LMA) requires an adequate depth of anesthesia. Optimal insertion conditions and hemodynamic stability during LMA insertion are mainly influenced by the choice of the intravenous induction agent. Propofol was recommended as a standard induction agent for LMA insertion. Read More

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Evaluation of Eye Alignment before and after Cataract Surgery.

J Binocul Vis Ocul Motil 2021 Jun 7:1-7. Epub 2021 Jun 7.

Department of Ophthalmology, Graduate School of Medicine, International University of Health and Welfare, Tokyo, Japan.

: To assess changes in eye alignment before and after cataract surgery.: The medical records of 786 cataract patients without eye movement limitation who underwent bilateral cataract surgery under topical anesthesia with monofocal IOL placement were retrospectively reviewed at the Eye Center of Sanno Hospital in Japan.: Before cataract surgery, 121 of the 786 patients (15. Read More

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Labial adhesions in a pre-pubertal girl: The importance of awareness.

Trop Doct 2021 Jun 7:494755211020901. Epub 2021 Jun 7.

Additional Professor, Department of Obstetrics and Gynaecology, Jawaharlal Institute of Post Graduate Medical Education and Research (JIPMER), Puducherry, India.

Labial adhesion affects up to 0.6-5% of pre-pubertal girls. They may be congenital or acquired. Read More

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A Clinical Analysis of Pharyngeal Bronchogenic Cysts in the Pharynx of Children.

Front Pediatr 2021 20;9:629009. Epub 2021 May 20.

Department of Otolaryngology Head and Neck Surgery, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, Beijing, China.

This study was designed to summarize the clinical characteristics, diagnosis and treatment of pharyngeal bronchogenic cysts in children to help in making the correct diagnosis and developing an appropriate treatment plan. The clinical data of 13 children with bronchogenic cysts in the pharynx, who were treated in otolaryngology head and neck surgery department between September 2013 and July 2019, were analyzed retrospectively. The clinical characteristics were evaluated, and the related factors for diagnosis and treatment were analyzed. Read More

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Use of Botulinum Toxin Injections for the Treatment of Chronic Anal Fissure: Results From an American Society of Colon and Rectal Surgeons Survey.

Am Surg 2021 Jun 7:31348211023446. Epub 2021 Jun 7.

Division of Colon and Rectal Surgery, 21886Advocate Lutheran General Hospital, Park Ridge, IL, USA.

Background: Chronic anal fissure (CAF) is commonly treated by colorectal surgeons. Pharmacological treatment is considered first-line therapy. An alternative treatment modality is chemical sphincterotomy with injection of botulinum toxin (BT). Read More

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Effect of pre-cooling agent on intensity of pricking pain at intraoral injection site in adults: An experimental study.

J Pak Med Assoc 2021 May;71(5):1379-1383

Department of Operative Dentistry, Dr. Ishrat ul Ebad Khan Institute of Oral Health Sciences, Karachi, Pakistan.

Objective: To determine the effect of pre-cooling agent on the intensity of pricking pain at the intraoral injection site in adult patients.

Methods: The in-vivo interventional study was conducted at the Department of Operative Dentistry, Dr. Ishrat-ul-Ebad Khan Institute of Oral Health Sciences, Dow University of Health Sciences, Karachi, from September 2018 to August 2019, and comprised adult patients of either gender. Read More

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Ophthalmia nodosa secondary to multiple intraocular caterpillar hairs in a 2-year-old girl.

Saudi J Ophthalmol 2020 Jul-Sep;34(3):230-232. Epub 2021 Feb 27.

Department of Ophthalmology, Dhahran Eye Specialist Hospital, Dhahran, Saudi Arabia.

A 2-year-old girl presented with pain, itching, photophobia, and tearing in her left eye. These symptoms started after contact with a caterpillar. The patient was initially taken to another hospital, where the local ophthalmologist prescribed topical prednisolone acetate 1%, a topical antibiotic, and cyclopentolate 1% eye drops. Read More

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February 2021

Comparison of Lidocaine Spray and Lidocaine Ice Popsicle in Patients Undergoing Unsedated Esophagogastroduodenoscopy: A Single Center Prospective Randomized Controlled Trial.

Clin Exp Gastroenterol 2021 25;14:209-216. Epub 2021 May 25.

Department of Anesthesiology, Faculty of Medicine, Thammasat University, Pathumthani, 12120, Thailand.

Purpose: Esophagogastroduodenoscopy (EGD) under topical pharyngeal anesthesia has the advantage of avoiding the unwanted cardiopulmonary adverse events experienced following intravenous sedation. Lidocaine spray is a common anesthetic option and is safe for unsedated EGD. Although several studies have compared different topical anesthetic agents, their formulations, and delivery techniques, questions still remain concerning the optimal mode of administration. Read More

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Transdermal Delivery of Lidocaine-Loaded Elastic Nano-Liposomes with Microneedle Array Pretreatment.

Biomedicines 2021 May 23;9(6). Epub 2021 May 23.

State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.

This study aimed to improve the transdermal delivery of lidocaine hydrochloride (LidH) using elastic nano-liposomes (ENLs) and microneedle (MN) array pretreatment. LidH-containing ENLs were prepared using soybean phosphatidylcholine and cholesterol, with Span 80 or Tween 80, using a reverse-phase evaporation method. The ENL particle size, stability, and encapsulation efficiency (EE) were characterized and optimized based on the component ratio, pH, and type of surfactant used. Read More

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Chalazion: racial risk factors for formation, recurrence, and surgical intervention.

Can J Ophthalmol 2021 May 29. Epub 2021 May 29.

University of Wisconsin, Madison Department of Ophthalmology and Visual Sciences, Madison, Wisc.. Electronic address:

Background: An association between race and formation of chalazion has yet to be objectively established. This study investigates race as a risk factor for chalazion and chalazion surgery. Understanding racial risk factors in formation of chalazion, recurrent chalazion, and chalazion requiring surgery (often with general anesthesia in children) informs decisions regarding eyelid hygiene, early topical medical therapy, and aggressiveness with oral antibiotic therapy for coexisting conditions such as blepharitis. Read More

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Bilateral posterior scleritis presenting as acute primary angle closure: A case report.

Authors:
Chao Wen Hui Duan

World J Clin Cases 2021 May;9(15):3779-3786

Department of Ophthalmology, The First Affiliated Hospital of Dalian Medical University, Dalian 116001, Liaoning Province, China.

Background: Scleritis is a rare disease and the incidence of bilateral posterior scleritis is even rarer. Unfortunately, misdiagnosis of the latter is common due to its insidious onset, atypical symptoms, and varied manifestations. We report here a case of bilateral posterior scleritis that presented with acute eye pain and intraocular hypertension, and was initially misdiagnosed as acute primary angle closure. Read More

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Comparing topical administration of lidocaine alone and in combination with alfentanil in children undergoing bronchoscopy.

J Family Med Prim Care 2021 Mar 8;10(3):1332-1335. Epub 2021 Apr 8.

Department of Anaesthesiology, Children's Hospital Medical Centre, Tehran University of Medical Sciences, Tehran, Iran.

Introduction: Airway surgery and endoscopy in pediatric patients are always associated with challenges in anesthesia management. Deep anesthesia is required for preventing patient bucking during the procedure but patient breath should be maintained; in this regard, a combination of general and topical anesthesia can be beneficial. There is also evidence of the peripheral effects of opioids. Read More

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Focused ultrasound enhances the anesthetic effects of topical lidocaine in rats.

BMC Anesthesiol 2021 May 21;21(1):158. Epub 2021 May 21.

Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, 02115, Boston, MA, USA.

Background: High-intensity ultrasound has been used to induce acoustic cavitation in the skin and subsequently enhances skin permeability to deliver hydrophobic topical medications including lidocaine. In contrast, instead of changing skin permeability, pulsed application of low-intensity focused ultrasound (FUS) has shown to non-invasively and temporarily disrupt drug-plasma protein binding, thus has potential to enhance the anesthetic effects of hydrophilic lidocaine hydrochloride through unbinding it from serum/interstitial α1-acid glycoprotein (AAG).

Methods: FUS, operating at fundamental frequency of 500 kHz, was applied pulse-mode (55-ms pulse duration, 4-Hz pulse repetition frequency) at a spatial-peak pulse-average intensity of 5 W/cm. Read More

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Comparison of the efficacy of growth factor collagen and antibiotic collagen on colon anastomosis in  experimental animals with peritonitis.

Indian J Gastroenterol 2021 Jun 21;40(3):309-315. Epub 2021 May 21.

Meram Medical Faculty, Department of General Surgery, Necmettin Erbakan University, 42080, Konya, Turkey.

Introduction: In spite of advances in surgical techniques, the significance of anastomosis leak continues in colorectal surgery. There is no ideal method in spite of all studies and technical advances in this field. Our aim of this study was to use fibroblast growth factor collagen (FGF-C) and antibiotic collagen (AB-C) to increase the rate of anastomosis healing in experimental animals with peritonitis. Read More

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Two Different Methods Of Lidocaine Inhalation Before Diagnostic Flexible Bronchoscopy: Effects On Post-Bronchoscopy Respiratory Symptoms.

Turk J Med Sci 2021 May 20. Epub 2021 May 20.

Introduction: Use of topical anesthesia before flexible bronchoscopy for the evaluation of the upper airways prevents cough and stridor during and after the procedure while reducing the need for sedation. In practice, lidocaine is the medication of choice before bronchoscopy. There various types of nebulizers used for inhalation treatments. Read More

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Drop homotopic effects of masseter-muscle pain on somatosensory sensitivity in healthy participants.

Sci Rep 2021 May 19;11(1):10575. Epub 2021 May 19.

Division of Oral Function and Rehabilitation, Department of Oral Health Science, Nihon University School of Dentistry at Matsudo, 2-870-1, Sakaecho-nishi, Matsudo, Chiba, 271-8587, Japan.

Current pain classifications use 1.0-kg palpation of the masseter muscle to distinguish between "pain patients" and "healthy controls" but a thorough understanding of the normal physiological responses to various somatosensory stimuli is lacking. The aim of this study was to investigate somatosensory function of the skin over the masseter muscle in healthy participants that were divided into a masseter pain prone group (MPP) (n = 22) and non-MPP group (n = 22), according to the response to a 1. Read More

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Corrigendum to 'Proteomic changes in the hippocampus and motor cortex in a rat model of cerebral palsy: Effects of topical treatment' [Biomed. Pharmacother. 133 (2021) 110844].

Biomed Pharmacother 2021 Aug 15;140:111695. Epub 2021 May 15.

Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Department of Human Anatomy, Histology and Embryology, Neuroscience Center, Joint Laboratory of Anesthesia and Pain, School of Basic Medicine, Peking Union Medical College, 5 Dong Dan San Tiao, Dongcheng Districtl̥, Beijing 100005, China. Electronic address:

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Pain Perception in Cataract Surgery: Topical versus Peribulbar Anaesthesia.

Nepal J Ophthalmol 2021 Jan;13(25):50-58

Himalaya Eye Hospital, Gharipatan, Pokhara.

Introduction: The requirement for very deep akinesia has decreased with the use of modern phacoemulsification technique for cataract surgery. The use of topical anesthesia has increased as a way to reduce complications associated with anaesthesia with injection and to allow the most rapid visual recovery. The objective of this study was to assess the patient reported pain in phacoemulsification cataract surgery under topical anaesthesia versus peribulbar anaesthesia administered using an injection. Read More

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January 2021

Reliability of iCare ic100 Rebound Tonometry and agreement with Goldmann Applanation Tonometry in Healthy and Post-myopic LASIK Patients.

J Glaucoma 2021 May 12. Epub 2021 May 12.

Optometry Department, Oftalvist. Valencia, Spain Department of Optics & Optometry & Vision Sciences, University of Valencia. Valencia, Spain Alcocer Medical Centre. Valencia, Spain Avanza Vision Ophthalmology Clinic. Valencia, Spain.

Prcis: Rebound tonometry offers excellent reliability for obtaining IOP measurements in healthy and post-myopic LASIK patients regardless of corneal parameters and axial length and regardless of the instillation of ocular topical anesthesia.

Purpose: To assess the reliability of rebound tonometry, its agreement with Goldmann applanation tonometry (GAT) and its concordance after topical anesthesia in a group of non-operated healthy patients and a group of post-myopic laser-assisted in situ keratomileusis (LASIK) patients.

Patients And Methods: Fifty-four patients were included in this prospective observational, case-control study. Read More

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Perioperative anaphylaxis to intravenous vancomycin in a pediatric patient with previous topical exposures.

Ann Allergy Asthma Immunol 2021 May 7. Epub 2021 May 7.

Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.

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[Painless fiberoptic bronchoscopy in patients with COVID-19: analysis of 33 cases].

Nan Fang Yi Ke Da Xue Xue Bao 2021 Apr;41(4):562-566

Department of Anesthesiology, Wuhan First Hospital, Wuhan 430022, China.

Objective: To investigate the necessity, safety and feasibility of painless fiberoptic bronchoscopy in patients with coronavirus disease 2019 (COVID-19).

Objective: We retrospectively analyzed the clinical characteristics of 33 patients diagnosed with COVID-19 who received painless fiberoptic bronchoscopy in Wuhan First Hospital. The general demographic and clinical data of the patients including age, gender, and ASA classification were collected. Read More

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Lipid nanocapsules loaded with prilocaine and lidocaine and incorporated in gel for topical application.

Int J Pharm 2021 Jun 5;602:120675. Epub 2021 May 5.

Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas - UNICAMP, Campinas, São Paulo, Brazil. Electronic address:

Lipid nanocapsules (LNC) are special drug delivery system (DDS) carriers obtained by the phase-inversion temperature method (PIT). This study describes the encapsulation of the local anesthetics (LA) prilocaine (PLC) and lidocaine (LDC) in lipid nanocapsules (LNC) optimized by 2 factorial design, characterized through DLS, NTA, CRYO-EM and release kinetics and incorporated in carbopol gel (Gel) prior to in vivo anesthetic effect (in mice) evaluation. A very homogeneous population of small (50 nm; polydispersity index = 0. Read More

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Clinical Techniques: When and how to do a myringotomy - a practical guide.

Vet Dermatol 2021 Jun 6;32(3):302-e82. Epub 2021 May 6.

School of Veterinary Studies, University of Edinburgh Royal (Dick) Easter Bush Campus, Roslin, UK.

A myringotomy is a surgical incision made in the tympanic membrane (TM). This gives access to the middle ear for sampling, flushing and instilling topical therapy. It should be considered whenever the TM is intact and there is clinical evidence of otitis media, abnormal TMs and/or abnormal diagnostic imaging. Read More

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Corneal sensitivity is required for orientation in free-flying migratory bats.

Commun Biol 2021 May 5;4(1):522. Epub 2021 May 5.

Department of Evolutionary Ecology, Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany.

The exact anatomical location for an iron particle-based magnetic sense remains enigmatic in vertebrates. For mammals, findings from a cornea anaesthesia experiment in mole rats suggest that it carries the primary sensors for magnetoreception. Yet, this has never been tested in a free-ranging mammal. Read More

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Efficacy of xenon anesthesia in preventing postoperative cognitive dysfunction after cardiac and major non-cardiac surgeries in elderly patients: a topical review.

Med Gas Res 2021 Jul-Sep;11(3):110-113

Department of Anaesthesiology, Basavatarakam Indo-American Cancer Hospital and Research Institute, Hyderabad, India.

Elderly patients undergoing major cardiac and non-cardiac surgeries have a high propensity (up to 40-60%) of developing postoperative cognitive dysfunction, which are caused by patient's factors, type of surgery, intraoperative and postoperative factors. All these pose a challenge to the clinicians. The noble gas xenon does not undergo metabolism or any kind of biotransformation in the body owing to its inert nature. Read More

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The cricothyroid versus Spray-As-You-Go method for topical anesthesia during Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA): The CRISPEN randomized clinical trial.

Lung India 2021 May-Jun;38(3):223-228

Department of Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India.

Background: Guidelines for flexible bronchoscopy in adults recommend both Cricothyroid and Spray-as-you-go method as the acceptable techniques for lignocaine administration. No studies have compared these two methods for topical anesthesia during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA).

Objectives: Co-primary outcomes were the comparison of cough count and operator-rated overall procedure satisfaction on a Visual Analog Scale (VAS) between the groups. Read More

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