Search Our Scientific Publications & Authors

BMC Vet Res 2019 Jan 16;15(1):29. Epub 2019 Jan 16.

Faculty of Veterinary Medicine, University of Leipzig, Department for Horses, Leipzig, Germany.

Background: Despite appropriate medical therapy, many horses with equine recurrent uveitis continue to suffer from recurrent bouts of inflammation. Surgical intervention via the pars plana vitrectomy or suprachoroidal cyclosporine implant placement may control and/or prevent recurrences, however, these procedures may be contraindicated, unavailable, or declined by an owner. Thus, an effective adjunctive treatment option may help to improve the clinical outcomes in those situations. Read More

G Ital Cardiol (Rome) 2019 Jan;20(1):41-45

U.O.C. Cardiologia-UTIC.

Background: The aim of this study was to report our experience with subcutaneous defibrillator (S-ICD) implantation.

Methods: At our hospital, 7 procedures of S-ICD implantation were performed; 4 of these with ultrasound-guided serratus anterior plane block (SAPB) and 3 with usual local anesthesia followed by sedation.

Results: Surgical operations were not burdened with peri- and postprocedural complications, with only one event of limited hematoma of the thoracic wall. Read More

Int Urogynecol J 2019 Jan 7. Epub 2019 Jan 7.

National Institute of Neurological Disorders and Stroke, National Institutes of Health, Building 31; Room B2 B32, 9000 Rockville Pike, Bethesda, MD, USA.

Introduction And Hypothesis: Botulinum toxin (BoNT) is increasingly used for pain, especially with muscle spasm. We describe our methodology for BoNT treatment of chronic pelvic pain (CPP) in women and place it in the context of the literature on techniques for this use.

Methods: Databases were searched using terms "botulinum toxin," "pelvic pain," and "vaginismus. Read More

Medicine (Baltimore) 2019 Jan;98(1):e14035

Department of Pediatric Pulmonology and Immunology, West China Second University Hospital of Sichuan University.

This retrospective study investigated the application of the sedation-agitation scale (SAS) in pediatric bronchoscopy by observing its effects on sedative dosages and adverse reactions.Children who underwent sedation before bronchoscopy, during the period from January 2014 to June 2017, were divided into control and SAS groups. Patients in the control group were administered a single dose of 0. Read More

Otolaryngol Head Neck Surg 2019 Jan 1:194599818821905. Epub 2019 Jan 1.

2 Division of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Utah, Salt Lake City, Utah, USA.

Objective: To compare the efficacy, safety, and cost of incision and drainage (I&D) for pediatric patients with peritonsillar abscesses (PTAs) under conscious sedation (CS) versus unsedated (awake) and general anesthesia (GA).

Study Design: Case series with chart review.

Setting: Tertiary pediatric hospital. Read More

J Res Med Sci 2018 28;23:102. Epub 2018 Nov 28.

Department of Gastroenterology and Hepatology, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Advantage of using local sedation during upper gastrointestinal endoscopy (UGE) is still challenging. In the current study, the effect of lidocaine spray versus lidocaine viscous solution for pharyngeal local anesthesia during UGE has been compared.

Materials And Methods: This is a randomized clinical trial conducted on 130 patients conducting UGE in 2013. Read More

Surg Technol Int 2018 Dec 20;34. Epub 2018 Dec 20.

Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI.

Lung cancer remains the leading cause of cancer death in the United States, and accounts for more deaths than breast, colon, and prostate cancer combined. Over the past decade, percutaneous thermal ablative therapy (PTA) has become a useful adjunctive therapy in combination with longer-standing methods, or as a standalone treatment. The physiologic basis of thermal ablation is that coagulative necrosis and cell death occur at temperatures above 60°C. Read More

J Cardiothorac Vasc Anesth 2018 Nov 14. Epub 2018 Nov 14.

Department of Anesthesia and Pain Management, Toronto General Hospital, Toronto, Canada. Electronic address:

Objective(s): This study was designed to compare 2 different perioperative analgesia strategies with respect to the incidence of postoperative delirium after a transapical approach for transcatheter aortic valve replacement (TAVR). The authors hypothesized that perioperative thoracic paravertebral analgesia with a local anesthetic would decrease opioid consumption and in turn reduce the incidence of postoperative delirium when compared with systemic opioid-based analgesia after a transapical TAVR procedure.

Design: Prospective, randomized controlled clinical trial. Read More

Can J Urol 2018 Dec;25(6):9596-9600

MD/PhD Program, Texas A & M Health Science Center College of Medicine, Temple, Texas, USA.

Introduction: Stent placement is a common procedure for addressing obstructive uropathy. However, lack of operating room (OR) availability can substantially delay this procedure. In this study, we sought to assess the feasibility, safety, and efficacy of this procedure in a clinical setting using nitrous oxide (N2O) and local anesthesia. Read More

J Craniofac Surg 2018 Dec 13. Epub 2018 Dec 13.

Dental/Medical Center of Maxillofacial Surgery "Aleja-Centar," Banja Luka, Bosnia and Herzegovina.

Septoplasty is usually performed under general anesthesia or local anesthesia with sedation. Nevertheless, septoplasty under pure local anesthesia is also feasible and it shows a great potential for fast-track surgery. This article presents a patient with nasal septal deviation where septoplasty was managed under local anesthesia at an outpatient clinic. Read More

J Minim Invasive Gynecol 2018 Dec 7. Epub 2018 Dec 7.

Department of Women's Health and Territorial Medicine (Dr. De Angelis), University of Rome "La Sapienza", Rome, Italy.

Study Objective: To compare the effectiveness and safety of different techniques of hysteroscopic polypectomy.

Design: Multicenter, prospective observational trial (Canadian Task Force classification II-2).

Setting: Nineteen Italian gynecologic departments (university-affiliated or public hospitals). Read More

J Thorac Dis 2018 Nov;10(Suppl 30):S3588-S3594

Department of Anesthesia & Perioperative Medicine, University of Western Ontario, London, ON, Canada.

There is currently significant controversy regarding the best anesthesia management for patients undergoing transcatheter aortic valve replacement (TAVR). Some institutions primarily use general anesthesia (GA) but many institutions primarily use moderate sedation. Much of the controversy is due to the limited evidence base available to inform this decision and the strong feelings and pre-conceived notions about the optimal anesthesia technique which exist amongst anesthesiologists, cardiologists, and cardiac surgeons. Read More

J Pediatr Surg 2018 Nov 6. Epub 2018 Nov 6.

Department of Paediatric Surgery, St Georges Hospital NHS Trust, London, UK. Electronic address:

Objective: The objective of this study was to report our multidisciplinary diagnostic approach for patients with anterior mediastinal masses (AMM).

Methods: A retrospective review of patients with AMM at a tertiary pediatric surgical oncology centre (January 2011-December 2016) was performed. We analyzed data on clinical presentation, mode of tissue diagnosis, anesthetic techniques, and complications. Read More

Hand (N Y) 2018 Dec 2:1558944718813721. Epub 2018 Dec 2.

3 Centro Universitário Serra dos Órgãos, Teresópolis, Brazil.

Background: The purpose of this study was to evaluate the safety and efficacy of ambulatory open surgical treatment for carpal tunnel syndrome with local anesthesia and without tourniquet ischemia, sedation by an anesthesiologist, or hospitalization.

Methods: A retrospective analysis of 60 consecutive cases performed during 1 year was conducted, excluding other compressive or noncompressive neuropathies. The criteria for treatment efficacy were improvements in symptoms and recurrence rates, and the safety criterion was the presence of complications. Read More

Einstein (Sao Paulo) 2018 Nov 29;16(4):eAO4279. Epub 2018 Nov 29.

Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.

Objective: To evaluate safety and effectiveness of nodule volume reduction and thyroid function after percutaneous laser ablation treatment in patients with benign nonfunctioning thyroid nodules.

Methods: Prospective single-center study, from January 2011 to October 2012, which evaluated 30 euthyroid and thyroid antibodies negative patients with benign solitary or dominant nodule with indication of treatment due to compressive symptoms and aesthetic disturbances. The clinical and laboratory (thyroid ultrasound, TSH, FT4, TG, TG-Ab, TPO-Ab and TRAb levels) evaluations were performed before the procedure, and periodically 1 week, 3 months and 6 months after. Read More

Ann Chir Plast Esthet 2018 Nov 30. Epub 2018 Nov 30.

Département de chirurgie plastique, reconstructrice, brûlés, plaies et cicatrisation, CHU Lapeyronie, 371, avenue de Doyen Gaston Giraud, 34295 Montpellier, France. Electronic address:

Objectives: Blepharopoiesis represents a double aesthetic and functional challenge. If anterior lamellar reconstruction is less discussed, the variety of posterior lamellar substitutes testifies that none is ideal. We report here our experience of the use of autologous dermal dermis as posterior lamellar substitutes in bilamellar blepharopoiesis. Read More

Rev Bras Anestesiol 2019 Jan - Feb;69(1):27-34. Epub 2018 Oct 25.

Universidade Federal de Minas Gerais (UFMG), Faculdade de Medicina, Belo Horizonte, MG, Brasil; Faculdade de Minas (Faminas), Belo Horizonte, MG, Brasil. Electronic address:

Background And Objectives: The combination of clonidine with local anesthetic administered for epidural anesthesia via caudal route seems to improve the quality of postoperative analgesia, but with conflicting results. This study compared the postoperative analgesia of three different doses of clonidine combined with bupivacaine in caudal epidural anesthesia in children undergoing hypospadias repair.

Methods: Eighty children aged 1 to 10 years, candidates for surgical repair of hypospadias, were randomly divided into four groups of 20 patients to receive general anesthesia combined with caudal epidural anesthesia with bupivacaine 0. Read More

Hand Clin 2019 Feb;35(1):21-27

Department of Plastic and Reconstructive Surgery, Dalhousie University, Suite C204, 600 Main Street, Saint John, New Brunswick E2K1J5, Canada.

Clinic-based hand surgery performed under local anesthetic has been steadily increasingly performed in Canada for 50 years. The drive for its development stems from the Canadian health care system's finite funding structure and resources. Benefits have extended far beyond cost and garbage reduction. Read More

Hand Clin 2019 Feb;35(1):1-6

Division of Plastic Surgery, Dalhousie University, Dalhousie Medicine New Brunswick, Suite C204, 600 Main Street, Saint John, New Brunswick E2K 1J5, Canada. Electronic address:

Injection of tumescent local anesthesia should no longer be painful. WALANT anesthesia, strong sutures, a slightly bulky repair, intraoperative testing of active movement, and judicious venting of the A2 and A4 pulleys improve results in flexor tendon repair. WALANT K wire finger fracture reduction permits intraoperative testing of K wire stability with active movement to facilitate early protected movement at 3 to 5 days after surgery. Read More

J Neurol 2018 Nov 20. Epub 2018 Nov 20.

Department of Orthopedic Surgery, RKU-University and Rehabilitation Clinics, Ulm University, Ulm, Germany.

Spinal muscular atrophy is a genetic motor neuron disease that leads to progressive muscular atrophy and muscle weakness. In December 2016, the Food and Drug Administration, and in June 2017, the European Medicines Agency approved the antisense oligonucleotide nusinersen for treatment of spinal muscular atrophy. Nusinersen has to be repeatedly administered intrathecally. Read More

BJU Int 2018 Nov 15. Epub 2018 Nov 15.

Department of Urology, Guy's at St Thomas' Hospitals, London, UK.

Introduction: Systematic transperineal (TP) and targeted prostate biopsies can be achieved using a freehand access system through perineal punctures, with the potential for reduced morbidity and enabling the procedure under local anesthesia (LA), particularly sepsis.

Objectives: To evaluate the histopathological outcomes, morbidity and tolerability of freehand TP prostate biopsies using the PrecisionPoint access system under local anaesthetic (LA) in the day surgery and outpatient environments.

Methods: 176 patients underwent freehand TP prostate biopsies from May 2016 to November 2017. Read More

Saudi J Anaesth 2018 Oct-Dec;12(4):559-564

Department of Anesthesia and Intensive Care, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Background: Thoracolumbar interfascial plane (TLIP) block involves injection of local anesthetics between multifidus and longissimus muscles at the 3 lumbar vertebral level assuming that it can block the dorsal rami of thoracolumbar nerves.

Objective: The objective of this study was to evaluate the analgesic effects gained after performing TLIP block (analogous to the transversus abdominis plane [TAP] block, but intended for the back) in patients undergoing lumbar discectomy.

Methodology: This was a prospective, randomized, double-blinded, controlled clinical trial. Read More

Minerva Anestesiol 2018 Dec 30;84(12):1413-1419. Epub 2018 Oct 30.

Departments of General Anesthesiology and Outcomes Research, Cleveland Clinic, Cleveland, OH, USA.

Preoperative nil per os (NPO) guidelines have been in existence since the recognition of the risk of perioperative aspiration. These guidelines aim at reducing the risk for gastric content aspiration to the lowest possible, to avoid associated morbidity, unplanned hospital and/or an intensive care admission. Thus, such guidelines are not only considered for patients having major surgeries, but more so in those having ambulatory surgery including those performed at non-operating room anesthesia locations. Read More

Aesthet Surg J 2018 Nov;38(12):NP230

Plastic surgeon in private practice in Chesterfield, MO.

Aesthet Surg J 2018 Nov;38(12):NP229

Retired plastic surgeon in Carmel, IN.

Pan Afr Med J 2018 13;30:128. Epub 2018 Jun 13.

Centre Hospitalier Universitaire Aristide Le Dantec, Dakar, Senegal.

Penile strangulation is a clinical condition requiring emergency management. Several metallic or non-metallic objects can be placed around the penis to improve sexual performance or for auto-erotic purposes. We report the case of two schizophrenic patients aged 25 and 33years hospitalized in the Emergency Department due to penile strangulation by metal ring. Read More

Cardiovasc Drugs Ther 2018 Dec;32(6):625-632

Department of Cardiology, Santa Maria della Misericordia Hospital, Viale Tre Martiri 140, 45100, Rovigo, Italy.

Over the last years, fentanyl, a potent synthetic μ receptor-stimulating opioid, has become one of the most used drugs for both procedural analgesia and sedation in patients undergoing coronary angiography (CA) and/or percutaneous coronary intervention (PCI). However, few studies have been performed to evaluate the efficacy and the impact of this drug in patients with coronary artery disease (CAD) treated with PCI. Most of the previous studies have investigated the self-reported discomfort pain, demonstrating that patients premedicated with fentanyl generally reported a lower pain/discomfort when compared to placebo, benzodiazepines, or local anesthesia at the site of the artery cannulation, without significant variation in the hemodynamic response. Read More

Pediatr Dent 2018 Sep;40(5):365-369

Professor, in the Department of Oral Health, Faculty of Dentistry, Universidade Federal de Goias, Goiania-GO, Brazil.

Little is known about psychological factors associated with children's behavior during dental sedation. The purpose of this study was to investigate the associations between parental dental anxiety, coping style, pain catastrophizing (an exaggerated negative response to pain), and children's behavior during dental treatment under moderate sedation. Participants included 110 pairs consisting of mothers, fathers, or grandmothers and healthy children (60 boys, 50 girls; mean age equals 47. Read More

Ann Otol Rhinol Laryngol 2018 Oct 20:3489418806922. Epub 2018 Oct 20.

1 University Avenue Halifax, Halifax, NS, Canada.

Objectives: The aim of this study was to assess the feasibility and safety of ossiculoplasty under local anesthesia in an office setting without sedation.

Methods: Between May 2017 and November 2017, patients who presented with conductive hearing loss and known isolated ossicular discontinuities were offered ossiculoplasty under local anesthesia. Inclusion criteria included age ⩾ 18 years, adequate transcanal access, and the ability to lie supine for up to 45 minutes. Read More

Vet Anaesth Analg 2019 Jan 19;46(1):126-134. Epub 2018 Sep 19.

Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA.

Objective: To assess the feasibility, success rate, onset, duration and extent of motor/sensory block following intrathecal injection of lidocaine in bearded dragons (Pogona vitticeps).

Study Design: Prospective experimental study.

Animals: A group of eight adult bearded dragons (0. Read More

Br J Anaesth 2018 Nov 1;121(5):1059-1064. Epub 2018 Aug 1.

Department of Anaesthesiology, CHU Liège, University of Liège, Domaine du Sart Tilman, Liège, Belgium. Electronic address:

Background: Propofol use during sedation for colonoscopy can result in cardiopulmonary complications. Intravenous lidocaine can alleviate visceral pain and decrease propofol requirements during surgery. We tested the hypothesis that i. Read More

Orbit 2018 Oct 18:1-3. Epub 2018 Oct 18.

a Eye Research Center , Mashhad University of Medical Sciences , Mashhad , Iran.

Subperiosteal hematoma of the orbit is a rare complication that may occur in different situations. The most common cause is blunt trauma to the head region. The victims are usually young boys and the common site is usually orbital roof. Read More

Aesthet Surg J 2018 Oct 12. Epub 2018 Oct 12.

Departments of Surgery and Obstetrics and Gynaeocology, Monash University, Melbourne, Victoria, Australia.

J Craniomaxillofac Surg 2018 Dec 21;46(12):2088-2095. Epub 2018 Sep 21.

Oral and Maxillofacial Surgery Department, Clínica Platón, Barcelona, Spain.

Purpose: To evaluate the benefits of performing mentoplasty using custom guides and plates in a series of 23 patients.

Patients And Methods: An 18-month observational study in 23 patients (16 women, 7 men) who underwent procedures for chin augmentation (n = 15), reduction and centering mentoplasty (n = 6), chin asymmetry correction (n = 1) and placement of a custom chin implant to correct esthetics (n = 1) was conducted in the Department of Oral and Maxillofacial Surgery of Hospital Universitario Dexeus (Barcelona, Spain).

Results: A mentoplasty technique using customized surgical guides and plates, performed under local anesthesia and oral sedation, was performed in every case. Read More

Anesth Analg 2018 Oct 9. Epub 2018 Oct 9.

Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada.

Background: Both dexamethasone and dexmedetomidine are effective peripheral nerve block (PNB) perineural adjuncts that prolong block duration. However, each is associated with side effects. With paucity of head-to-head comparisons of these adjuncts, the question of the best adjunct to mix with local anesthetics (LA) for PNB is unanswered. Read More

Korean J Anesthesiol 2018 10 10. Epub 2018 Oct 10.

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Background: To identify trends in injuries and substandard care associated with anesthesia, we analyzed the Korean Society of Anesthesiologists database, which includes anesthesia-related case files from July 2009 to June 2018.

Methods: Case characteristics, injuries, and outcomes were compared between the first part (July 2009-June 2014, n = 105) and the second part (July 2014-June 2018, n = 92) of the analyzed time period.

Results: Overall, 132 cases resulted in death. Read More

J Clin Anesth 2018 Oct 3;53:35-38. Epub 2018 Oct 3.

Nîmes University Hospital, Nîmes, France.

Background: While the incidence of postoperative delirium is high in aged hospitalized patients undergoing major surgery, little is known concerning patients undergoing ambulatory surgery.

Objective: To determine the incidence of postoperative delirium in aged patients after hospital discharge from an ambulatory surgery unit.

Design: Prospective observational study. Read More

J Contemp Dent Pract 2018 Sep 1;19(9):1157-1160. Epub 2018 Sep 1.

Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.

Background: Myotonic dystrophy type I (DM1) is a genetic autosomal dominant disorder; malignant hyperthermia is a possible complication. It may occur following administration of some halogenated general anesthetics, muscle relaxants, or surgical stress.

Aim: The purpose of this case report is to evaluate the dental management of patients with Steinert's disease. Read More

J Hand Surg Am 2018 Oct;43(10):913-919

Rothman Institute, Thomas Jefferson University, Philadelphia, PA.

Purpose: Adequate postoperative pain control in hand surgery is a multifactorial issue affecting patient satisfaction, outcomes, and safety. However, prescription opioid abuse is becoming an increasingly prevalent problem in the Unites States. The purpose of this study was to determine if there was a difference in pain levels or pill consumption when using nonopioids, ibuprofen (IBU) and acetaminophen (ACE), versus an opioid, oxycodone (OXY), after carpal tunnel release (CTR) performed exclusively under local anesthesia without sedation. Read More

Int J Spine Surg 2018 Jun 15;12(3):342-351. Epub 2018 Aug 15.

Center for Advanced Spine Care of Southern Arizona, Tucson, Arizona; University of Arizona, Tucson, Arizona; Department of Neurosurgery, Universidade Federal do Estado do Rio de Janeiro-UNIRIO, Rio de Janeiro, Brazil.

Background: The objective of this study was to analyze readmission rates after outpatient transforaminal endoscopic decompression surgery for lumbar foraminal and lateral recess stenosis done in an ambulatory surgery center. Endoscopic lumbar spinal surgery is gaining popularity for the treatment of lumbar disc herniations. Recent advances in surgical techniques allow for percutaneous endoscopically assisted bony decompression for neurogenic claudication symptoms due to spinal stenosis. Read More

Orthod Fr 2018 09 26;89(3):279-288. Epub 2018 Sep 26.

Faculté d'Odontologie,rue Guillaume Paradin 69372 Lyon cedex 08, France.

Introduction: The aim of this systematic literature review is to propose a clinical protocol in 2018 by comparing therapeutic efficacy and undesirable effects of the technique.

Materials And Methods: Searches were made on Pubmed/Medline and Cochrane for randomized clinical trials and case series involving mandibular symphyseal distraction over the past 20 years with a patient sample greater than or equal to 10.

Results: Of the 92 articles, 25 met the inclusion criteria. Read More

Tuberk Toraks 2018 Jun;66(2):109-114

Clinic of Chest Diseases, Istanbul Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, Istanbul, Turkey.

Introduction: Endobronchial ultrasonography (EBUS) is an endoscopic method that aids needle aspiration to see the bronchial wall and adjacent tissues with an ultrasound probe. Pulmonary arteries are rarely present between the bronchus wall and the tissue. In this case, it was necessary to make a selection between invasive processes and transbronchial needle aspiration (TBNA) through the pulmonary artery. Read More

Reumatol Clin 2018 Sep 19. Epub 2018 Sep 19.

Servicio de Reumatología, Hospital General Universitario Gregorio Marañón, Madrid, España.

Objective: Intra-articular corticosteroid injections (IACI) are a fundamental part in the treatment of juvenile idiopathic arthritis. The current situation of IACI is reviewed in a population of children.

Methods: We conducted a narrative review of the literature related to IACI in children, with respect to the injection technique, use of local and general anesthesia, ultrasound guidance of the procedure, indications, special joints and type of optimal corticosteroid. Read More

Acad Emerg Med 2018 Sep 21. Epub 2018 Sep 21.

Department of Emergency Medicine, California Hospital Med Center, Los Angeles, CA.

Objectives: We wanted to estimate the frequency and describe the nature of emergency department (ED) procedural sedation restrictions in the State of California.

Methods: We surveyed medical directors for all licensed EDs statewide regarding limitations on procedural sedation practice. Our primary outcome was the frequency of restrictions on procedural sedation, defined as an inability to administer moderate sedation, deep sedation, and typical ED sedative agents in accordance with American College of Emergency Physicians (ACEP) guidelines. Read More

Anaesthesist 2018 Nov;67(11):871-877

Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Köln (AöR), Köln, Deutschland.

Background: Neurodegeneration with brain iron accumulation (NBIA) forms a group of rare hereditary diseases with rapid neurodegenerative progression due to an abnormal accumulation of iron in the basal ganglia. This causes extrapyramidal symptoms as well as dystonia and mental retardation. The most common form of NBIA is pantothenate kinase-associated neurodegeneration (PKAN, formerly Hallervorden-Spatz syndrome). Read More

Anesth Prog 2018 ;65(3):168-176

Division of Dental Anesthesiology, Department of Oral Surgery, Ohu University School of Dentistry, Fukushima, Japan.

Dexmedetomidine (DEX) is a sedative and analgesic agent that acts via the alpha-2 adrenoreceptor and is associated with reduced anesthetic requirements, as well as attenuated blood pressure and heart rate in response to stressful events. A previous study reported that cat gingival blood flow was controlled via sympathetic alpha-adrenergic fibers involved in vasoconstriction. In the present study, experiment 1 focused on the relationship between the effects of DEX on alpha adrenoreceptors and vasoconstriction in the tissues of the oral cavity and compared the palatal mucosal blood flow (PMBF) in rabbits between general anesthesia with sevoflurane and sedation with DEX. Read More

Expert Rev Cardiovasc Ther 2018 Oct 28;16(10):749-756. Epub 2018 Sep 28.

a Interventional Cardiology and Cardiovascular Surgery Centre Hospitalier Regional , Universitaire de Lille (CHRU de Lille) , Lille , France.

Introduction: Alternative transcatheter aortic valve implantation (TAVI) approaches offer the possibility of valve replacement in patients ineligible to the transfemoral route. Authors provide an updated review of the existing alternative approaches. Areas covered: A systematic review of alternative approaches for TAVI was undertaken. Read More

Mayo Clin Proc Innov Qual Outcomes 2017 Sep 2;1(2):176-184. Epub 2017 Aug 2.

Department of Otorhinolaryngology, Mayo Clinic, Rochester, MN.

Objective: To describe the treatment of adult velopharyngeal insufficiency (VPI) with injection of a hyaluronic acid and dextranomer copolymer (Dx/HA).

Patients And Methods: This was a retrospective case series of 25 consecutively treated adults with VPI who underwent Dx/HA injection pharyngoplasty in a multidisciplinary clinic from January 1, 2011, to December 31, 2014. Data recorded included etiology of VPI, perceptual analysis of resonance, nasalance scores, and estimation of velopharyngeal gap characteristics on video nasendoscopy before and after the intervention. Read More

J Interv Card Electrophysiol 2018 Sep 14. Epub 2018 Sep 14.

Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany.

Background: The subcutaneous implantable cardioverter-defibrillator (S-ICD) system is an established therapy for the prevention of sudden cardiac death (SCD) and an alternative to a transvenous implantable cardioverter-defibrillator (ICD) system in selected patients. S-ICDs are usually implanted under general anesthesia. The purpose of the present study was to describe the technical feasibility and safety of local anesthesia with conscious sedation as an alternative to general anesthesia during S-ICD implantation using the intermuscular technique. Read More