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Anesth Analg 2020 Jun 4. Epub 2020 Jun 4.

Department of Anesthesia, The Queen Elizabeth Hospital, Woodville, South Australia - 5011, Australia.

Current evidence suggests that Coronavirus Disease 2019 (COVID-19) spread occurs via respiratory droplets (particles >5 µm), and possibly through aerosol. The rate of transmission remains high during airway management. This was evident during the 2003 severe acute respiratory syndrome epidemic where those who were involved in tracheal intubation had a higher risk of infection than those who were not involved (odds ratio 6. Read More

Arthrosc Tech 2020 May 22;9(5):e593-e598. Epub 2020 May 22.

Kansas City University, Kansas City, Missouri, U.S.A.

Needle arthroscopic procedures of the knee offer potential advantages over standard arthroscopic procedures. The small size of the instruments allows for surgery without the use of a scalpel or suture, potentially decreased recovery times, and potentially reduced complication rates compared with traditional arthroscopy. In some patients, the procedure can be performed without the use of either general anesthesia or sedation. Read More

Front Vet Sci 2020 14;7:232. Epub 2020 May 14.

Department of Clinical Sciences, New Bolton Center, University of Pennsylvania, Philadelphia, PA, United States.

Horses underwent either cervical epidural space (CES) catheterization or subarachnoid space (SAS) catheterization while restrained in stocks, under deep sedation (detomidine and morphine) and local anesthesia (mepivacaine 2%) block. Catheters were placed under ultrasound guidance with visualization of the dura, SAS, and spinal cord between the first (C1) and second (C2) cervical vertebrae. Following sedation and sterile skin preparation, operator 1 placed under ultrasound guidance, a 6- or 8-inch Tuohy needle with the bevel oriented caudally. Read More

Rev Bras Anestesiol 2020 May 12. Epub 2020 May 12.

Seth G.S. Medical College, Department of Anaesthesia, Mumbai, India. Electronic address:

Morbid obesity is associated with various pathophysiological changes which affect the outcome of anesthesia and surgery. So it's challenging to give anesthesia to such patients. We present a 59-year-old adult morbidly obese, hypertensive, diabetic female with hypothyroidism operated for proximal humerus fracture and now presented with non-union of fracture, requiring percutaneous injection of bone marrow aspirate from the iliac crest to the site of non-union. Read More

Anaesthesist 2020 May 29. Epub 2020 May 29.

Abteilung für Anästhesie, Intensiv‑, Rettungs- und Schmerzmedizin, BG-Klinikum Hamburg, Bergedorfer Str. 10, 21033, Hamburg, Deutschland.

As a single and reliable parameter for prediction of the difficult airway is missing, the specialist societies for anesthesiology recommend the use of scores that combine the individual parameters. Contemporary scores include head-neck mobility, mouth opening and anatomical distances. Their training and correct performance are essential. Read More

Vet Surg 2020 May 28. Epub 2020 May 28.

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.

Objective: To compare the effectiveness of a paravertebral nerve block vs local portal blocks for laparoscopic closure of the nephrosplenic space in standing sedated research horses.

Study Design: Randomized clinical trial.

Animals: Twelve horses were randomly allocated to two groups (n = 6 per group), paravertebral block of nerves T , L , and L or local blocks of the three laparoscopic portals. Read More

Diagn Interv Radiol 2020 May 21. Epub 2020 May 21.

Purpose: Nusinersen is a drug approved in December 2016 for treatment of spinal muscular atrophy (SMA). We want to share our initial experience with image-guided, non-image-guided, and port-delivered nusinersen injections in a large single-center SMA patient cohort, treating both pediatric and adult patients with focus on technical considerations and other patient concerns from a combined perspective of patient, neurologist, and radiologist.

Methods: All nusinersen injections between February 2017 and September 2018 were retrospectively reviewed. Read More

Pacing Clin Electrophysiol 2020 May 18. Epub 2020 May 18.

Cardiology Unit, "Card. Giovanni Panico" Hospital, Tricase, Italy.

Background: The standard approach to subcutaneous defibrillator (S-ICD) implantation often requires general anesthesia or anesthesiologist-delivered deep sedation. Ultrasound-guided serratus anterior plane block (SAPB) combined with parasternal block (PSB) has been proposed in order to provide anesthesia/analgesia and to reduce the need for sedation during S-ICD implantation. In this pilot study, we compared the double-block approach (SAPB + PSB) with the single-block approach (SAPB only) and with the standard approach involving local anesthesia and sedation. Read More

World J Transplant 2020 Apr;10(4):79-89

Division of Nephrology, Department of Internal Medicine, Diskapi Research and Training Hospital, Health Sciences University, Ankara 06110, Turkey.

Background: Both end-stage renal disease and being wait-listed for a kidney transplant are anxiety-causing situations. Wait-listed patients usually require arteriovenous fistula surgery for dialysis access. This procedure is performed under local anesthesia. Read More

Clin J Pain 2020 May 8. Epub 2020 May 8.

Department of Dental Anesthesiology, Field of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University.

Objective: Local anesthesia is essential for pain management in dentistry. The duration of anesthetic action of addition of 5.0 and 7. Read More

Female Pelvic Med Reconstr Surg 2020 May 8. Epub 2020 May 8.

Department of Obstetrics and Gynecology Herlev & Gentofte University Hospital Herlev, Denmark University of Copenhagen Copenhagen, Denmark

Pediatrics 2020 Jun 12;145(6). Epub 2020 May 12.

Department of Pediatrics and Bioethics Center, Children's Mercy Hospital, Kansas City, Missouri

A 15-year-old girl is scheduled to undergo an upper lobectomy to debulk metastatic Ewing sarcoma. The anesthesiologist recommended placement of a thoracic epidural catheter to provide postoperative analgesia. The patient did not want a needle to be placed near her spine. Read More

Interv Neuroradiol 2020 May 6:1591019920923831. Epub 2020 May 6.

Department of Radiology, Mayo Clinic, Rochester, MN, USA.

Purpose: Compare functional outcomes of acute ischemic stroke patients undergoing embolectomy with either local anesthesia or conscious sedation. Secondarily, identify differences in hemodynamic parameters and complication rates between groups.

Materials And Methods: Single institution, retrospective review of all acute ischemic stroke patients undergoing embolectomy between January 2014 and July 2018 ( = 185). Read More

Spec Care Dentist 2020 May 1;40(3):308-314. Epub 2020 May 1.

Department of Preventive Dentistry, Faculty of Dentistry, Umm Al-Qura University, Makkah, Saudi Arabia.

Background: Factor X deficiency (known as; Stuart-Prower factor deficiency or F10 deficiency) is a rare inherited bleeding disorder. It affects one per 1 million individuals worldwide. Patients with inherited bleeding disorder reported difficulty in accessing primary dental care either due to their medical diseases or their related barriers. Read More

J Clin Med 2020 Apr 24;9(4). Epub 2020 Apr 24.

School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Universiteitssingel 40, 6229 ER Maastricht, The Netherlands.

Background: Microelectrode recordings (MER) are used to optimize lead placement during subthalamic nucleus deep brain stimulation (STN-DBS). To obtain reliable MER, surgery is usually performed while patients are awake. Procedural sedation and analgesia (PSA) is often desirable to improve patient comfort, anxiolysis and pain relief. Read More

Oral Maxillofac Surg 2020 Apr 27. Epub 2020 Apr 27.

Anesthesiology and Resuscitation, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan.

Objective: We aimed to investigate the usefulness of glucose administration for maintaining perioperative glycemic control in patients with dietary restrictions during 4 h prior to impacted mandibular third molar extraction under intravenous sedation.

Methods: Fifty-four individuals scheduled to undergo extraction of impacted mandibular third molars under intravenous sedation, with preoperative blood glucose levels (GL) of 70-110 mg/dL, were evaluated and divided into 3 groups (n = 18 each): control group receiving glucose-free sodium lactate Ringer's solution, perioperative GL group receiving 100 mL of 5% glucose solution immediately after local anesthesia, and postoperative GL group receiving 100 mL of 5% glucose solution immediately after surgery completion. Blood glucose levels, systolic blood pressure, diastolic blood pressure, and heart rate were measured. Read More

Curr Opin Anaesthesiol 2020 Jun;33(3):368-373

Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia.

Purpose Of Review: This review describes maternal and fetal anesthetic management for noncardiac fetal surgical procedures, including the management of lower urinary tract obstruction, congenital diaphragmatic hernia (CDH), myelomeningocele, sacrococcygeal teratoma, prenatally anticipated difficult airway and congenital lung lesions.

Recent Findings: Fetal interventions range from minimally invasive fetoscopic procedures to mid-gestation open surgery, to ex-utero intrapartum treatment procedure. Anesthetic management depends on the fetal intervention and patient characteristics. Read More

J Cardiothorac Surg 2020 Apr 22;15(1):68. Epub 2020 Apr 22.

Department of Cardiovascular Surgery, The Second Affiliated Hospital of Hainan Medical University, 48th of Bai Shui Tang Road, Haikou, Hainan, People's Republic of China, 570311.

Background: Patent ductus arteriosus (PDA) is a common congenital heart disease. Interventional therapy is an important treatment for PDA. Nevertheless, few studies have investigated the safety and effectiveness of interventional therapy for infants (age, 0-36 months) with PDA and moderate-to-severe pulmonary hypertension. Read More

Eur J Clin Pharmacol 2020 Apr 22. Epub 2020 Apr 22.

Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

Purpose: The aim of this study was to evaluate the quality of spinal anesthesia and hemodynamic parameters of intravenous versus intrathecal dexmedetomidine in patients undergoing inguinal hernia repair surgery under spinal anesthesia.

Methods: Fifty male patients aged 18-70 years with ASA I and II were randomly divided into two groups of 25 patients receiving either intravenous (1 μg/kg infused during 10 min before blockade) or intrathecal (5 μg, added to local anesthetics) dexmedetomidine. The duration of analgesia, sensory and motor blockade levels, the score of pain intensity, post-operative analgesic usage and the level of sedation as well as hemodynamic changes, and complications were recorded. Read More

Can J Anaesth 2020 Jul 14;67(7):877-884. Epub 2020 Apr 14.

Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.

Purpose: Essential tremor (ET) is a common movement disorder with disability in voluntary actions such as eating and writing. First-line treatment involves pharmacological agents, although efficacy is limited by side effects. In these patients, functional neurosurgery can be considered. Read More

Am J Emerg Med 2020 Mar 19. Epub 2020 Mar 19.

Department of Emergency Medicine, Seoul National University Hospital, Seoul, Republic of Korea.

Purpose: The objective of this study was to evaluate whether sedation with ketamine without local anesthesia was sufficient in children undergoing primary repair.

Methods: Randomized, double-blind trial conducted between December 2013 and October 2016 in a tertiary care pediatric emergency department in Korea. Children aged 1 to 10 years requiring sedation for primary repair were randomly assigned to receive local lidocaine anesthesia with ketamine sedation or local saline injection with ketamine sedation. Read More

Vet Anaesth Analg 2020 May 8;47(3):396-404. Epub 2020 Feb 8.

Department of Veterinary Surgery and Anesthesiology, Faculty of Veterinary Medicine, University of Western São Paulo, São Paulo, Brazil. Electronic address:

Objective: To investigate the intraperitoneal (IP) administration of ropivacaine or ropivacaine-dexmedetomidine for postoperative analgesia in cats undergoing ovariohysterectomy.

Study Design: Prospective, randomized, blinded, positively controlled clinical study.

Animals: A total of 45 client-owned cats were enrolled. Read More

Pediatr Emerg Care 2020 Mar 12. Epub 2020 Mar 12.

From the Department of Emergency Medicine, Bucheon Hospital of Soonchunhyang University, Bucheon, South Korea.

Purpose: To show the efficacy of cartoon as a distraction technique in suturing a child patient in the emergency room.

Methods: We studied children aged 2 to 8 years who had sustained a facial laceration 3 cm or less that required suturing from September 2015 to November 2016. We used local anesthesia and attempted to place the sutures without sedation while showing the children cartoons instead. Read More

J Spine Surg 2020 Jan;6(Suppl 1):S294-S299

Department of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.

Full endoscopic surgery including discectomy (FED) and ventral facetectomy (FEVF) is a minimally invasive lumbar decompression surgery that only requires an 8 mm skin incision and can be done under the local anesthesia and sedation. Six male medical doctors underwent the endoscopic decompression (FED/FEVF) for common degenerative lumbar spine problems. Their age ranged from 27 to 63 years of age with a mean of 40 years. Read More

J Spine Surg 2020 Jan;6(Suppl 1):S120-S132

Department of Orthopaedics, DWS Spine Clinic Center Santiago, Santiago, Chile.

Background: The indications of different endoscopic and endoscopically assisted translaminar approaches for lumbar spinal stenosis are not well-defined, and validated protocols for the use of the transforaminal over the interlaminar approach are lacking.

Methods: We performed a retrospective study employing an image-based patient stratification protocol of stenosis location (type I-central canal, type II-lateral recess, type III-foraminal, type IV-extraforaminal) and clinical outcomes on 249 patients consisting of 137 (55%) men and 112 (45%) women with an average age of 56.03±16. Read More

J Spine Surg 2020 Jan;6(Suppl 1):S116-S119

Veterans General Hospital, Taichung, Taiwan.

Background: Worker's compensation (WC) patients undergoing spine surgery typically experience delayed return to work (RTW) compared with non-WC patients, especially those approved for surgery undergoing traditional open spine surgery. The purpose of this study was to describe the observe RTW rates in WC patients after minimally invasive "selective endoscopic discectomy" (SED™) for a lumbar herniated disc.

Methods: Clinical outcomes using the modified Macnab criteria and RTW data were analyzed in 118 WC patients following the outpatient SED™ procedure in an ambulatory surgery center (ASC) using only local anesthesia with or without sedation. Read More

Anesth Prog 2020 ;67(1):48-59

Private Practice, Special Care Dentistry of Oklahoma, Oklahoma City, Oklahoma.

For decades, the dental profession has provided the full spectrum of anesthesia services ranging from local anesthesia to general anesthesia in the office-based ambulatory environment to alleviate pain and anxiety. However, despite a reported record of safety, complications occasionally occur. Two common contributing factors to general anesthesia and sedation complications are medication errors and adverse drug events. Read More

J Oral Maxillofac Surg 2020 Jun 19;78(6):973-978. Epub 2020 Feb 19.

Head, Maxillofacial Surgery Unit, Department of Neuroscience, Reproductive and Odontostomatological Sciences, Università degli Studi Federico II di Napoli, Naples, Italy.

Purpose: We evaluated the outcomes and differences in surgical time and hospitalization length for patients with an isolated zygomatic arch (ZA) fracture treated by percutaneous wire reduction with external fixation.

Patients And Methods: We designed and developed a retrospective study of patients with isolated ZA fractures treated from 2014 to 2019. The predictor variable was the operative treatment, represented by percutaneous reduction with external fixation. Read More

J Appl Toxicol 2020 Mar 13. Epub 2020 Mar 13.

Department of Anesthesiology, Laboratory of Anesthesia and Critical Care Medicine, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

ET-26 hydrochloride (ET-26HCl), a novel analog of etomidate, induces as effective sedation, with good cardiac and respiratory stability, as etomidate but with mild adrenocortical suppression. The objective of this study was to evaluate the potential adverse effects of ET-26HCl in rats. In a single-dose toxicity study, abnormal urine color (red) was observed in all groups: control (100%), 8 mg/kg (10%), 16 mg/kg (50%), and 20 mg/kg (70%) ET-26HCl, which returned to normal on the day of dosing. Read More

Med Oncol 2020 Mar 12;37(4):22. Epub 2020 Mar 12.

Department of Radiology, San Paolo Hospital, Via A. Di Rudinì 8, 20142, Milan, Italy.

Radiofrequency ablation is a minimally invasive procedure alternative to surgery to treat benign thyroid nodules causing compressive symptoms. Tolerability of this procedure, aimed at treatment of benign conditions, is fundamental. In this study, we evaluated if local anesthesia should be enough to reduce both hospital costs and sedation-related risks for the patient, avoiding deep sedation and presence of the anesthesiologist. Read More

Laryngoscope 2020 May 11;130 Suppl 4:S1-S9. Epub 2020 Mar 11.

Ear Medical Group, San Antonio, Texas, U.S.A.

Objectives/hypothesis: Evaluate technical success, tolerability, and safety of lidocaine iontophoresis and tympanostomy tube placement for children in an office setting.

Study Design: Prospective individual cohort study.

Methods: This prospective multicenter study evaluated in-office tube placement in children ages 6 months through 12 years of age. Read More

JPRAS Open 2020 Mar 2;23:26-31. Epub 2019 Nov 2.

Division of Plastic and Reconstructive Surgery, Department of Surgery, Rutgers - New Jersey Medical School, Newark, NJ, USA.

Purpose: Carpal tunnel release, one of the most commonly performed procedures in Veterans Affairs (VA) medical centers, is often performed under local anesthesia alone. In this patient population, there is an increased prevalence of psychiatric disorders. Our hypothesis is that there is no difference in operating time, request for sedation, or complications in the veteran population with or without a recognized psychiatric history. Read More

Eurasian J Med 2020 Feb;52(1):16-20

Department of Anesthesiology and Reanimation, Ataturk University School of Medicine, Erzurum, Turkey.

Objective: Since initial description by Forero for thoracic region, ultrasound guided erector spinae plane (ESP) block has experienced several surgeries for postoperative pain management, chronic pain or surgical anesthesia. Although ESP block has been reported to provide effective analgesia in the thoracic region, its effect in lumbar region still unclear. In this study we aimed to showed our successful experience with lumbar ESP block as a main anesthetic technique in fifteen high risk elderly patients undergoing hip surgery with mild propofol sedation. Read More

PLoS One 2020 6;15(3):e0230079. Epub 2020 Mar 6.

Département de Sciences Cliniques, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, Canada.

This study aimed to evaluate the analgesic efficacy of two dosage regimens using two different concentrations of buprenorphine in cats undergoing dental extractions. Twenty-three cats with oral disease (8.2 ± 2. Read More

Acta Neurochir (Wien) 2020 Mar 4. Epub 2020 Mar 4.

Department of Anesthesiology and Critical Care, St-Louis-Lariboisière-Fernand Widal University Hospitals, APHP, Paris, France.

Background: Awake surgery has become a key treatment of diffuse low-grade gliomas (DLGG) and is divided in three main phases: opening, tumor resection - during which the patient needs to be fully awake - and closure. The anesthetic management of awake neurosurgery is a challenge, and there are currently no guidelines.

Objective: The objective of the survey was to explore differences and commonalities regarding the anesthetic management of awake DLGG surgery within the European Low-Grade Glioma Network (ELGGN) centers. Read More

Actas Urol Esp 2020 Apr 29;44(3):196-204. Epub 2020 Feb 29.

Hospital Arnau de Vilanova, Valencia, España.

Introduction: Prostate cancer is the most common visceral neoplasm in men and the second one in the United States with the highest mortality behind lung cancer and ahead of colorectal cancer. While prostate cancer mortality rates have been reduced in the United States, Austria, United Kingdom and France, 5-year survival rates have been incremented in Sweden, probably due to a higher diagnostic activity and non-lethal tumor detection. TRPB usually has low rates of serious complications, with a not negligible number of minor complications. Read More

Surg Neurol Int 2020 14;11:23. Epub 2020 Feb 14.

Spine Department and Deformities, Interbalkan European Medical Center, Thessaloniki, Greece.

Background: Motor neuron disease includes a spectrum of neurodegenerative diseases with progressive courses and unfavorable prognoses. Here, we described a patient with a lumbar disc herniation (LDH) and isolated bulbar palsy (IBP), who successfully underwent a transforaminal full-endoscopic discectomy (TFED) without incurring the added risks of general anesthesia.

Case Description: A 58-year-old male with IBP had an LDH at the L4-L5 level. Read More

Rev Bras Ortop (Sao Paulo) 2020 Feb 28;55(1):48-53. Epub 2020 Feb 28.

Faculdade de Medicina do ABC, Santo André, SP, Brasil.

 To evaluate the clinical and functional results of transforaminal endoscopic lumbar discectomy.  From August 2015 to January 2017, 101 patients with lumbar disc hernia refractory to clinical treatment underwent endoscopic discectomy. Through clinical evaluation by the Visual Analogue Scale and functional evaluation by the Oswestry Disability Index questionnaire, the patients were analyzed in the preoperative period, the immediate postoperative period, at 1 month, 3 months, 6 months and 1 year after surgery. Read More

Int J Environ Res Public Health 2020 02 26;17(5). Epub 2020 Feb 26.

Department of Otolaryngology Head and Neck Surgery and Maxillofacial Surgery Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Tel-Aviv 6139001, Israel.

Until recently, the treatment for molar incisor hypomineralization (MIH) mainly included interim restorations such as resin restorations and stainless-steel crowns. These require replacement after adolescence. The use of intraoral scanners (IOS) has opened a new venue for restoring MIH teeth, by reducing the challenge of dealing with uncooperative children's behavior and enabling tooth structure preservation and long-lasting restoration. Read More

J Bronchology Interv Pulmonol 2020 Feb 25. Epub 2020 Feb 25.

Department of Pulmonary and Critical Care Medicine, Saint Louis University Hospital, Saint Louis, MO.

Background: Conflicting evidence of nebulized lidocaine use in bronchoscopy still exist. This study will identify whether there is any difference in various patient-related, physician-related, or procedure-related outcomes with and without lidocaine nebulization before the procedure.

Method: The authors performed a search in 4 electronic databases, including Pubmed, Scopus, Virtual Health Library, and Google Scholar from inception to August 2019. Read More

Turk Gogus Kalp Damar Cerrahisi Derg 2019 Oct 23;27(4):508-511. Epub 2019 Oct 23.

Department of Cardiovascular Surgery, Ankara Training and Research Hospital, Ankara, Turkey.

Background: In this study, we aimed to present our mid-term results of basilic vein transposition in the forearm to create an arteriovenous fistula.

Methods: Between January 2015 and October 2017, a total of 21 patients (13 males, 8 females; mean age 54.2±11. Read More

J Voice 2020 Feb 17. Epub 2020 Feb 17.

Department of Otolaryngology - Head and Neck Surgery, Drexel University College of Medicine, Philadelphia, Pennsylvania; Lankenau Institute for Medical Research, Pennsylvania. Electronic address:

Objectives: The objectives of this study were to determine the rate of hemorrhage following type I thyroplasty performed exclusively with Gore-Tex implant and to define whether age, comorbidities, anticoagulation therapy, presence of vocal fold ectasia, and operative technique are associated with increased incidence of hemorrhage.

Methods: Medical charts of 86 patients who underwent type I thyroplasty with Gore-Tex implant between the years 2013 and 2019 were reviewed retrospectively and divided into two groups based on presence or absence of postoperative vocal fold hemorrhage. Patients were examined on the day following surgery. Read More

Qatar Med J 2019 6;2019(2). Epub 2020 Feb 6.

Trauma Intensive Care Unit (TICU), Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.

Trauma is a leading cause of mortality and morbidity worldwide, and thus represents a great global health challenge. The World Health Organization (WHO) estimated that 9% of deaths in the world are the result of trauma. In addition, approximately 100 million people are temporarily or permanently disabled every year. Read More

Neuromodulation 2020 Feb 19. Epub 2020 Feb 19.

Department of Anesthesiology and Pain Clinic, AZ Delta Roeselare-Torhout-Menen, Roeselare, Belgium.

Objectives: Different anesthesia techniques are used for surgical implantation of paddle lead electrodes for neurostimulation through a laminectomy. We wanted to evaluate the use of dexmedetomidine as sedative for this procedure in a series of patients. Second, we wanted to verify whether the stimulation pattern and position of the electrode had to be changed during the procedure guided by the patient's feedback. Read More

Beijing Da Xue Xue Bao Yi Xue Ban 2020 Feb;52(1):181-186

Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.

Objective: To analyze the clinical data of patients undergoing intravenous sedation in oral and maxillofacial surgery, to understand the epidemiological characteristics, to evaluate the efficacy and safety of intravenous sedation for oral surgery, and to summarize our experience.

Methods: We retrospectively reviewed the clinical data of patients undergoing intravenous sedation between January 2010 and December 2018 in the Department of Oral and Maxillofacial Surgery, Peking University School of Stomatology. The gender, age, source, disease types, the values of perioperative vital signs, the use of sedatives and analgesics, duration of surgery and sedation, effect of sedation during the operation and the postoperative anterograde amnesia were analyzed. Read More

Front Vet Sci 2019 23;6:478. Epub 2020 Jan 23.

Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

Orchiectomy is performed in some species using only sedation and local anesthesia to decrease the expense of performing the procedure using general anesthesia. The objective of this study was to determine if dogs can be castrated safely and painlessly by using only sedation and local anesthesia. After dogs were sedated with intramuscularly administered xylazine (1 mg/kg) and subanesthetic ketamine (1 mg/kg), testes and skin were anesthetized with 2% lidocaine (6 mg/kg, total dose) buffered with sodium bicarbonate. Read More

Ophthalmology 2019 Dec 25. Epub 2019 Dec 25.

Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Purpose: To evaluate the types of anesthesia-related closed claims and their contributing factors, using data from the Ophthalmic Mutual Insurance Company (OMIC).

Design: Retrospective analysis of preexisting data.

Participants: Plaintiffs who filed a professional liability claim or suit (written demand for money) against OMIC-insured ophthalmologists, ophthalmic practices, or surgicenters in which the surgical case occurred. Read More

J Clin Anesth 2020 Jun 7;62:109725. Epub 2020 Feb 7.

Department of Anesthesia, Women's Hospital, Zhejiang University School of Medicine, Xueshi Road 1#, Hangzhou, Zhejiang 310006, China. Electronic address:

Study Objective: Studies have showed that intrathecal dexmedetomidine as supplements to local anesthetics can improve the quality of the spinal anesthesia and reduce the local anesthetic requirement of spinal anesthesia for cesarean section. However, the magnitude of this effect has not been fully quantified. Therefore, we conducted the present study to investigate the ED of intrathecal hyperbaric ropivacaine with or without dexmedetomidine for cesarean section in healthy parturients. Read More

Agri 2020 Jan;32(1):44-47

Department of Urology, Ataturk University Faculty of Medicine, Erzurum, Turkey.

Extracorporeal shockwave lithotripsy (ESWL) is widely used for the treatment of urinary tract calculi; however, the vast majority of the patients does not tolerate the procedure without analgesia and sedation. Pain control in ESWL has been crucial for process success and patient comfort. Systemic drugs, such as non-steroid anti-inflammatory drugs, opioids, alfa-2 agonist and various local and regional anesthesia methods (transversus abdominis plane block, paravertebral block, infiltration) have been applied to control ESWL pain. Read More

Neuroimage Clin 2020 21;25:102188. Epub 2020 Jan 21.

Research Center for Brain-inspired Intelligence and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China; University of Chinese Academy of Sciences, Beijing, China; Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Beijing, China. Electronic address:

Background: General anesthesia (GA) provides an invaluable experimental tool to understand the essential neural mechanisms underlying consciousness. Previous neuroimaging studies have shown the functional integration and segregation of brain functional networks during anesthetic-induced alteration of consciousness. However, the organization pattern of hubs in functional brain networks remains unclear. Read More