3,647 results match your criteria Anesthesia Ear


A model to predict postoperative complications for otorhinolaryngology and maxillofacial surgery procedures in elderly patients.

Eur Arch Otorhinolaryngol 2020 Jun 3. Epub 2020 Jun 3.

Head and Neck and Robotic Surgery, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

Purpose: All kinds of ear, nose, and throat and maxillofacial surgery (ENT/MFS) procedures are being increasingly performed in the elderly although old age is a major risk factor for increased postoperative complications. With only scarce evidence on the topic, surgeons are asked to critically evaluate their procedures' indications and outcomes to balance the treatment risks and benefits. Our primary aim was to identify predictive factors for surgical outcomes in this setting and to create a predictive model for a tailored risk assessment. Read More

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http://dx.doi.org/10.1007/s00405-020-06084-7DOI Listing

Diagnosis of Stapedial Myoclonus Using Endoscopic Visualization.

Otol Neurotol 2020 May 28. Epub 2020 May 28.

Department of Otology and Laryngology, Harvard Medical School.

Background: Stapedial myoclonus is an uncommon condition involving the rhythmic contraction of the stapedial tendon that may result in a host of symptoms, including tinnitus (1-3). There is a dearth of robust diagnostic modalities to diagnose stapedial myoclonus(4-7), and most patients are treated without definitive diagnosis(8-12). Herein, we hypothesize that stapedial myoclonus can be readily diagnosed by awake otoendoscopy (see Video, Supplemental Digital Content 1, http://links. Read More

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http://dx.doi.org/10.1097/MAO.0000000000002716DOI Listing

Dynamic Reconfiguration, Fragmentation, and Integration of Whole-Brain Modular Structure across Depths of Unconsciousness.

Cereb Cortex 2020 May 29. Epub 2020 May 29.

Centre for Neuroscience Studies, Queen's University, Kingston, K7L 3N6, Ontario, Canada.

General anesthetics are routinely used to induce unconsciousness, and much is known about their effects on receptor function and single neuron activity. Much less is known about how these local effects are manifest at the whole-brain level nor how they influence network dynamics, especially past the point of induced unconsciousness. Using resting-state functional magnetic resonance imaging (fMRI) with nonhuman primates, we investigated the dose-dependent effects of anesthesia on whole-brain temporal modular structure, following loss of consciousness. Read More

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http://dx.doi.org/10.1093/cercor/bhaa085DOI Listing

The Effect of Inferior Turbinate Surgery on Quality of Life: A Randomized, Placebo-Controlled Study.

Ear Nose Throat J 2020 May 26:145561320927944. Epub 2020 May 26.

Department of Otorhinolaryngology, Tampere University Hospital, Tampere, Finland.

Objective: The purpose of this prospective, randomized, single-blinded, placebo-controlled study was to investigate the effects of radiofrequency ablation (RFA), diode laser, and microdebrider-assisted inferior turbinoplasty (MAIT) techniques on patients' quality of life (QOL) and to compare the techniques with a placebo procedure.

Methods: A total of 98 consecutive patients with enlarged inferior turbinates due to persistent year-round rhinitis were randomized into placebo, RFA, diode laser, and MAIT groups at a ratio of 1:2:2:2. All the procedures were carried out under local anesthesia with the patients' eyes covered. Read More

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http://dx.doi.org/10.1177/0145561320927944DOI Listing

Bioengineered airway epithelial grafts with mucociliary function based on collagen IV- and laminin-containing extracellular matrix scaffolds.

Eur Respir J 2020 May 22. Epub 2020 May 22.

Lungs for Living Research Centre, UCL Respiratory, University College London, London, UK.

Current methods to replace damaged upper airway epithelium with exogenous cells are limited. Existing strategies use grafts that lack mucociliary function, leading to infection and the retention of secretions and keratin debris. Strategies that regenerate airway epithelium with mucociliary function are clearly desirable and would enable new treatments for complex airway disease. Read More

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http://dx.doi.org/10.1183/13993003.01200-2019DOI Listing

Local Versus General Anesthesia for Balloon Dilation of the Eustachian Tube: A Single-Center Retrospective Study in a Chinese Population.

Ear Nose Throat J 2020 May 19:145561320923172. Epub 2020 May 19.

Department of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Objective: To compare local anesthesia (LA) versus general anesthesia (GA) for balloon dilation of the Eustachian tube (BDET) using the Bielefeld Dilation System in a Chinese population with obstructive Eustachian tube dysfunction (OETD).

Methods: A total of 49 patients with OETD undergoing BDET under either LA or GA were included in the present study. Intraoperative blood pressure, heart rate, and pain sensation were recorded. Read More

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http://dx.doi.org/10.1177/0145561320923172DOI Listing

A comparison of difficult intubation documentation practices with existing guidelines in the advent of video laryngoscopy.

J Clin Anesth 2020 May 12;65:109807. Epub 2020 May 12.

Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA; Department of Anesthesiology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles St, Boston, MA 02114, USA. Electronic address:

Study Objective: To assess whether anesthesia providers' interpretations of a difficult intubation are consistent with current guidelines and explore possible explanations for any observed discrepancy including video laryngoscopy usage.

Design: A retrospective data analysis of tracheal intubation records from the electronic health record of a large healthcare system in the United States from January to June 2018.

Setting: General anesthesia encounters that involved a tracheal intubation in the operating rooms and non-operating room areas, including procedural areas, medical/surgical floors, and intensive care units. Read More

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http://dx.doi.org/10.1016/j.jclinane.2020.109807DOI Listing

Binaural Beats Reduce Postoperative Morphine Consumption in Older adults After Total Knee Replacement Surgery.

Altern Ther Health Med 2020 May 15. Epub 2020 May 15.

Context: A reduction in the use of opioids by older adult patients could reduce unpleasant side effects for them. During general anesthesia, binaural beat (BB) listening has been found to reduce intraoperative fentanyl consumption as well as postoperative pain scores and discharge time. Auditory BBs are a perceptual phenomenon occurring when tones of 2 slightly different frequencies are presented simultaneously and separately to each ear. Read More

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Long-term moderate noise exposure enhances the medial olivocochlear reflex.

Auris Nasus Larynx 2020 May 10. Epub 2020 May 10.

ENT Institute, Eye & ENT Hospital of Fudan University, Fenyang Road 83, Shanghai 200031, PR China; NHC Hearing Medicine Key Laboratory (Fudan University), Shanghai, PR China. Electronic address:

Objective: To investigate the effects of long-term moderate noise on hearing functions, MOCR, and MEMR.

Methods: Mice were exposed to the moderate noise (11.2 - 22. Read More

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http://dx.doi.org/10.1016/j.anl.2020.03.008DOI Listing

Multidisciplinary guidance for safe tracheostomy care during the COVID-19 pandemic: the NHS National Patient Safety Improvement Programme (NatPatSIP).

Anaesthesia 2020 May 12. Epub 2020 May 12.

Department of Anaesthesia and Intensive Care Medicine, Warrington and Halton Teaching Hospitals, Warrington, UK.

The COVID-19 pandemic is causing a significant increase in the number of patients requiring relatively prolonged invasive mechanical ventilation and an associated surge in patients who need a tracheostomy to facilitate weaning from respiratory support. In parallel, there has been a global increase in guidance from professional bodies representing staff who care for patients with tracheostomies at different points in their acute hospital journey, rehabilitation, and recovery. Of concern are the risks to healthcare staff of infection arising from tracheostomy insertion and subsequent management. Read More

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http://dx.doi.org/10.1111/anae.15120DOI Listing

Dental needle foreign body in the neck: a case report.

J Dent Anesth Pain Med 2020 Apr 27;20(2):83-87. Epub 2020 Apr 27.

Hamad Medical Corporation, Clinical Radiology and Medical Imaging Department, Doha, Qatar.

Foreign body (FB) ingestion is commonly seen in the ear nose and throat (ENT) field, with different presentations and sequelae. FBs can arrest in the upper aerodigestive tract or continue further down into either the airway tract to the bronchus or the digestive tract to the intestines. The pathway of an FB depends on the size and shape of the FB and how sharp its edges are. Read More

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http://dx.doi.org/10.17245/jdapm.2020.20.2.83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193060PMC

Effects of rabbit pinna-derived blastema cells on tendon healing.

Iran J Basic Med Sci 2020 Jan;23(1):13-19

Department of Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.

Objectives: Tendon healing is substantially slow and often associated with suboptimal repair. Cell therapy is one of the promising methods to improve tendon repair. Blastema, a population of undifferentiated cells, represents characteristics of pluripotent mesenchymal stem cells and has the potentials to be used in regenerative medicine. Read More

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http://dx.doi.org/10.22038/IJBMS.2019.29102.7045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206831PMC
January 2020

Can't intubate can't oxygenate: It takes more than a patent airway to oxygenate a patient.

Eur J Anaesthesiol 2020 Jun;37(6):503-504

From the Department of Anaesthesia, Great Western Hospital, Swindon (EB, JB) and Department of Anaesthesia, Royal National Throat, Nose and Ear Hospital, London, UK (JR).

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http://dx.doi.org/10.1097/EJA.0000000000001143DOI Listing
June 2020
3.011 Impact Factor

Henle fibre layer haemorrhage: clinical features and pathogenesis.

Br J Ophthalmol 2020 May 6. Epub 2020 May 6.

Retina Department, Vitreous Retina Macula Consultants of New York, New York, New York, USA.

Background: To describe the clinical presentation and characteristic imaging features of deep retinal haemorrhages primarily located in the Henle fibre layer (HFL) of the macula. The spectrum of aetiologies and a comprehensive theory of pathogenesis are presented.

Methods: This is a retrospective, multicentre case series evaluating eyes with retinal haemorrhage in HFL. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2019-315443DOI Listing

Awake tracheal intubation in a suspected COVID-19 patient with critical airway obstruction.

Anaesth Rep 2020 Jan-Jun;8(1):28-31. Epub 2020 May 4.

Department of Ear, Nose and Throat Surgery Guy's and St Thomas' Foundation Trust London UK.

We report the airway management of a patient with suspected COVID-19 with impending airway obstruction requiring urgent surgical tracheostomy. To our knowledge, this is the first reported case of an awake tracheal intubation in a suspected COVID-19-positive patient. Various modifications were put in place during the awake tracheal intubation and surgical tracheostomy procedures to minimise aerosol generation from the patient, such as avoiding high-flow nasal oxygen, establishing conscious sedation with remifentanil before commencing airway topicalisation and avoiding transtracheal local anaesthetic infiltration. Read More

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http://dx.doi.org/10.1002/anr3.12041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197305PMC

Anesthetic and Analgesic Efficient of Regional Nerve Blockade in Otoplasty.

J Craniofac Surg 2020 May 4. Epub 2020 May 4.

Yeni Yüzyil University, Health Occupation High-School Audiometry.

Aim: The prominent ear is the most common congenital deformity of the external ear. Otoplasty is performed to correct the appearance of the prominent ear. This study was planned to compare the analgesic and anesthetic effects of local nerve blockade and local infiltration anesthesia in the otoplasties. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006501DOI Listing

Estrogen receptor α activation aggravates imiquimod-induced psoriasis-like dermatitis in mice by enhancing dendritic cell interleukin-23 secretion.

J Appl Toxicol 2020 May 5. Epub 2020 May 5.

Laboratory of Veterinary Pharmacology, School of Veterinary Medicine, Azabu University, Sagamihara-shi, Kanagawa, Japan.

Our recent study has reported that estrogen receptors (ERs) are involved in several types of allergy development. This study aims to investigate the possible relationship between ER activation and development of imiquimod-induced psoriasis-like dermatitis. A mouse model of imiquimod-induced psoriasis-like dermatitis was generated by 5 days of topical application of 5% of imiquimod cream on the back of the ear and the shaved back skin of male BALB/c mice. Read More

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http://dx.doi.org/10.1002/jat.3988DOI Listing

RvE1 uses the LTB receptor BLT1 to increase [Ca] and stimulate mucin secretion in cultured rat and human conjunctival goblet cells.

Ocul Surf 2020 Jul 30;18(3):470-482. Epub 2020 Apr 30.

Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA. Electronic address:

Purpose: Specialized pro-resolving lipid mediator resolvin (Rv) E1 stimulates secretion including mucins from conjunctival goblet cells. RvE1 can use both its ChemR23 receptor and the LTB receptor BLT1 to increase [Ca]. The purpose of this study was to determine the expression of ChemR23 and BLT1 and receptors on conjunctival goblet cells and the respective roles these two receptors play in goblet cell responses to RvE1. Read More

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http://dx.doi.org/10.1016/j.jtos.2020.04.011DOI Listing

Apnoeic oxygenation and ventilation: go with the flow.

Anaesthesia 2020 Apr 29. Epub 2020 Apr 29.

Department of Anaesthesia, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1111/anae.15066DOI Listing

A Frameshift Variant in a Rottweiler Dog with Footpad Hyperkeratosis.

Genes (Basel) 2020 Apr 24;11(4). Epub 2020 Apr 24.

School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

A single male Rottweiler dog with severe footpad hyperkeratosis starting at an age of eight weeks was investigated. The hyperkeratosis was initially restricted to the footpads. The footpad lesions caused severe discomfort to the dog and had to be trimmed under anesthesia every 8-10 weeks. Read More

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http://dx.doi.org/10.3390/genes11040469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230267PMC

Efficacy of greater auricular and auriculotemporal nerve blocks performed in rabbits.

Vet Anaesth Analg 2020 Mar 8. Epub 2020 Mar 8.

Department of Surgical Sciences (Anesthesia), School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA.

Objective: To evaluate the efficacy, duration and safety of greater auricular and auriculotemporal nerve blocks in rabbits.

Study Design: Prospective, randomized, crossover, experimental study.

Animals: A total of 11 healthy adult Dutch-belted rabbits. Read More

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http://dx.doi.org/10.1016/j.vaa.2020.02.005DOI Listing

Evaluation of a Model of Long-Term Middle Ear Catheterization for Repeat Infusion Administration and Cochlear Hair Cell Injury in Guinea Pigs.

Toxicol Pathol 2020 Jun 23;48(4):586-592. Epub 2020 Apr 23.

Charles River Laboratories, Inc, Senneville, Quebec, Canada.

Middle ear administration has numerous applications, including antibiotherapy and gene therapy, and is increasingly used to target the auditory and vestibular systems. In animal studies, investigating repeated exposure that mimics clinical dosing regimens has remained a challenge due to the lack of suitable models. Intratympanic injections are not suitable for long-term studies due to the increased risk related to tympanic membrane rupture or scarring and repeat anesthesia events. Read More

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http://dx.doi.org/10.1177/0192623320916635DOI Listing

Chrysomya bezziana (Diptera: Calliphoridae) infestation in two Malaysian cats treated with oral lotilaner.

Vet Dermatol 2020 Apr 22. Epub 2020 Apr 22.

Lynn Veterinary Clinic, 39 JLN Opera K U2/K, TMN TTDI Jaya, 40150, Shah Alam, Selangor, Malaysia.

The most common fly species associated with screwworm myiasis in Southeast Asia is Chrysomya bezziana (Ch. bezziana), the Old-World screwworm. Treatment of screwworm myiasis in cats traditionally has comprised subcutaneous injection of ivermectin or oral administration of nitenpyram, combined with aggressive tissue debridement and larval removal under general anaesthesia. Read More

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http://dx.doi.org/10.1111/vde.12855DOI Listing

The prevalence of emergence delirium and its associated factors among children at a postoperative unit: A retrospective cohort at a Middle Eastern hospital.

Saudi J Anaesth 2020 Apr-Jun;14(2):169-176. Epub 2020 Mar 5.

King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.

Background: Emergence delirium (ED) has been reported among children at a postoperative setting, which delays their recovery and exposes them to traumas. The aim of this study was to determine the prevalence of ED and its associated factors among children who underwent surgeries at a major tertiary healthcare facility in Saudi Arabia.

Materials And Methods: Between March and August 2018, a retrospective cohort study was conducted based on a review of 413 medical charts of children (<14 years) who underwent an elective/nonemergency surgery and then were admitted to a Post Anesthesia Care Unit. Read More

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http://dx.doi.org/10.4103/sja.SJA_573_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164477PMC

Dissolving Microneedles for Rapid and Painless Local Anesthesia.

Pharmaceutics 2020 Apr 17;12(4). Epub 2020 Apr 17.

Department of Biotechnology, Building 123, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea.

Microneedles are emerging drug delivery methods for painless treatment. The current study tested dissolving microneedles containing lidocaine (Li-DMN) for use in local anesthesia. An Li-DMN patch was fabricated by centrifugal lithography with carboxymethyl cellulose as a structural polymer and assessed for physical properties by optical microscopy and a fracture force analyzer. Read More

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http://dx.doi.org/10.3390/pharmaceutics12040366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238259PMC

Emergency tracheal intubation in 202 patients with COVID-19 in Wuhan, China: lessons learnt and international expert recommendations.

Br J Anaesth 2020 Apr 10. Epub 2020 Apr 10.

Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

Tracheal intubation in coronavirus disease 2019 (COVID-19) patients creates a risk to physiologically compromised patients and to attending healthcare providers. Clinical information on airway management and expert recommendations in these patients are urgently needed. By analysing a two-centre retrospective observational case series from Wuhan, China, a panel of international airway management experts discussed the results and formulated consensus recommendations for the management of tracheal intubation in COVID-19 patients. Read More

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http://dx.doi.org/10.1016/j.bja.2020.03.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151238PMC
April 2020
4.853 Impact Factor

Assisted local anaesthesia for endoscopic dacryocystorhinostomy.

Clin Exp Ophthalmol 2020 Apr 20. Epub 2020 Apr 20.

Orbit, Plastic and Lacrimal Unit, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/ceo.13762DOI Listing

Anaesthesia and COVID-19: infection control.

Br J Anaesth 2020 Apr 8. Epub 2020 Apr 8.

Department of Anaesthesia and Perioperative Medicine, University College London Hospitals NHS Foundation Trust, UK. Electronic address:

The world is currently facing an unprecedented healthcare crisis caused by a pandemic novel beta coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The pathogen is spread by human-to-human transmission via droplets exposure and contact transfer, causing mild symptoms in the majority of cases, but critical illness, bilateral viral pneumonia, and acute respiratory distress syndrome (ARDS) in a minority. Currently, controlling infection to prevent the spread of SARS-CoV-2 is the primary public healthcare intervention used. Read More

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http://dx.doi.org/10.1016/j.bja.2020.03.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142687PMC

Gross Anatomical, Radiographic and Doppler Sonographic Approach to the Infra-auricular Parotid Region in Donkey (Equus asinus).

J Equine Vet Sci 2020 May 29;88:102968. Epub 2020 Feb 29.

Department of Surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.

The present study was performed on 12 heads of donkey's cadavers of both sexes for different anatomic techniques and on 20 live adult donkeys for ultrasonographic approaches of local anesthetic techniques. The aim was to achieve safe desensitization of the ear canal and tympanic membrane in addition to measuring different parameters of the structures occupying the infra-auricular parotid region. The internal auricular nerve was divided into two fine branches and constituting, at its origin, a characteristic V-shape with the caudal auricular nerve. Read More

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http://dx.doi.org/10.1016/j.jevs.2020.102968DOI Listing
May 2020
0.871 Impact Factor

[Superficial cervical plexus block in ear surgery: A case report].

Agri 2020 Apr;32(2):106-108

Department of Anesthesiology and Reanimation, Kocaeli University Faculty of Medicine, Kocaeli, Turkey.

The aim of this study was to share our experience with the application of a superficial cervical plexus block in the ear operation of a 59-year-old male patient. The superficial cervical plexus provides sensory innervation of the superficial structures of the anterolateral neck, ear, and shoulder. Ultrasound-guided cervical plexus block may be an alternative method for both anesthesia and analgesia in ear surgery. Read More

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http://dx.doi.org/10.5505/agri.2018.45762DOI Listing

Additional Benefits of Facial Nerve Monitoring during Otologic Surgery.

Otolaryngol Head Neck Surg 2020 Apr 14:194599820915458. Epub 2020 Apr 14.

Departments of Otolaryngology and Neurosurgery, LSU Health Sciences Center, New Orleans, Louisiana, USA.

Objective: This study assesses the role of facial nerve monitoring (FNM) for intraoperative decision making during otologic surgery and possible benefits beyond protecting facial nerve integrity.

Study Design: This prospective study examines intraoperative FNM data and structured interviews collected during 52 otologic procedures.

Setting: Tertiary referral center. Read More

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http://dx.doi.org/10.1177/0194599820915458DOI Listing

Rhinoliths: Analysis of 24 Interested Forgotten Foreign Body Cases.

Ear Nose Throat J 2020 Apr 13:145561320908477. Epub 2020 Apr 13.

Department of Otorhinolaringology, Healty Science University Hospital, Afyonkarahisar, Turkiye.

Rhinoliths are petrified masses formed by accumulation of endogenous or exogenous salts around a nidus. Although rarely formed by the body, the most common cause is foreign bodies forgotten in the nose at childhood. Rhinoliths are rare and have been reported as a single case report in the literature. Read More

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http://dx.doi.org/10.1177/0145561320908477DOI Listing

Tympanostomy Tube Controversies and Issues: State-of-the-Art Review.

Ear Nose Throat J 2020 Apr 13:145561320919656. Epub 2020 Apr 13.

Department of Otolaryngology, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.

Objective: To review current pragmatic issues and controversies related to tympanostomy tubes in children, in the context of current best research evidence plus expert opinion to provide nuance, address uncertainties, and fill evidence gaps.

Methods: Each issue or controversy is followed by the relevant current best evidence, expert insight and opinion, and recommendations for action. The role of expert opinion and experience in forming conclusions is inversely related to the quality, consistency, and adequacy of published evidence. Read More

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http://dx.doi.org/10.1177/0145561320919656DOI Listing

COVID-19 pandemic: Effects and evidence-based recommendations for otolaryngology and head and neck surgery practice.

Head Neck 2020 06 15;42(6):1259-1267. Epub 2020 Apr 15.

International Head and Neck Scientific Group, Udine, Italy.

The 2019 novel coronavirus disease (COVID-19) is a highly contagious zoonosis produced by SARS-CoV-2 that is spread human-to-human by respiratory secretions. It was declared by the WHO as a public health emergency. The most susceptible populations, needing mechanical ventilation, are the elderly and people with associated comorbidities. Read More

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http://dx.doi.org/10.1002/hed.26164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262203PMC

Consensus guidelines for managing the airway in patients with COVID-19: Guidelines from the Difficult Airway Society, the Association of Anaesthetists the Intensive Care Society, the Faculty of Intensive Care Medicine and the Royal College of Anaesthetists.

Anaesthesia 2020 06 1;75(6):785-799. Epub 2020 Apr 1.

Department of Anaesthesia and Intensive Care Medicine, Warrington and Halton NHS Foundation Trust, Warrington, UK.

Severe acute respiratory syndrome-corona virus-2, which causes coronavirus disease 2019 (COVID-19), is highly contagious. Airway management of patients with COVID-19 is high risk to staff and patients. We aimed to develop principles for airway management of patients with COVID-19 to encourage safe, accurate and swift performance. Read More

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http://dx.doi.org/10.1111/anae.15054DOI Listing

Failure to THRIVE: Non-intubated patients with elevated BMI are associated with increased desaturation events during transnasal humidified rapid-insufflation ventilatory exchange (THRIVE).

J Clin Anesth 2020 Aug 19;63:109793. Epub 2020 Mar 19.

Department of Anesthesiology, Massachusetts Eye and Ear, 243 Charles St., Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jclinane.2020.109793DOI Listing

Development of a Surgical Assessment Tool for National Policy Monitoring & Evaluation in Ethiopia: A Quality Improvement Study.

Int J Surg 2020 Mar 17. Epub 2020 Mar 17.

Federal Ministry of Health, Addis Ababa, Ethiopia. Electronic address:

Background: A baseline assessment of surgical capacity is recommended as a first-step to surgical system strengthening in order to inform national policy. In Ethiopia, the World Health Organization's Tool for Situational Analysis (WHO SAT) was adapted to assess surgical, obstetric, and anesthesia capacity as part of a national initiative: Saving Lives Through Safe Surgery (SaLTS). This study describes the process of adapting this tool and initial results. Read More

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http://dx.doi.org/10.1016/j.ijsu.2020.03.025DOI Listing

The Evolving Treatment of Diabetic Retinopathy.

Clin Ophthalmol 2020 4;14:653-678. Epub 2020 Mar 4.

Retina Center of Minnesota, Minneapolis, MN 55404, USA.

Purpose: To review the current therapeutic options for the management of diabetic retinopathy (DR) and diabetic macular edema (DME) and examine the evidence for integration of laser and pharmacotherapy.

Methods: A review of the PubMed database was performed using the search terms diabetic retinopathy, diabetic macular edema, neovascularization, laser photocoagulation, intravitreal injection, vascular endothelial growth factor (VEGF), vitrectomy, pars plana vitreous surgery, antiangiogenic therapy. With additional cross-referencing, this yielded 835 publications of which 301 were selected based on content and relevance. Read More

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http://dx.doi.org/10.2147/OPTH.S236637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061411PMC

Is Nasal Septum Deviation Severity a Significant Factor on Voice in Patients Undergoing Septoplasty?

J Coll Physicians Surg Pak 2020 03;30(3):287-291

Ankara Numune Training and Research Hospital ENT & HNS Clinic, Hacettepe Mahallesi Talatpaşa Bulvarı No.44 Altındağ, Ankara, Turkey.

Objective: To determine whether septoplasty is an effective factor on the voice in patients with varying degrees of nasal septum deviation.

Study Design: Descriptive study.

Place And Duration Of Study: Ankara Numune Training and Research Hospital, Ear Nose Throat Clinic, Ankara, Turkey, from November 2018 to March 2019. Read More

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http://dx.doi.org/10.29271/jcpsp.2020.03.287DOI Listing

In-Office Tympanostomy Tube Placement in Children Using Iontophoresis and Automated Tube Delivery.

Laryngoscope 2020 May 11;130 Suppl 4:S1-S9. Epub 2020 Mar 11.

Ear Medical Group, San Antonio, Texas, U.S.A.

Objectives/hypothesis: Evaluate technical success, tolerability, and safety of lidocaine iontophoresis and tympanostomy tube placement for children in an office setting.

Study Design: Prospective individual cohort study.

Methods: This prospective multicenter study evaluated in-office tube placement in children ages 6 months through 12 years of age. Read More

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http://dx.doi.org/10.1002/lary.28612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187287PMC

Evaluation of Potential Systemic Adverse Events Related to Fluorescein Angiography in Pediatric Patients.

Ophthalmol Retina 2019 Dec 16. Epub 2019 Dec 16.

Department of Ophthalmology, Weill Cornell Medical College, New York, New York; Department of Ophthalmology & Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois. Electronic address:

Purpose: To evaluate adverse events of fluorescein angiography (FA) in pediatric patients.

Design: Single-institution retrospective chart review.

Participants: Patients 0 to 18 years of age who underwent FA between January 2010 and December 2015 at a single institution in the United States. Read More

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http://dx.doi.org/10.1016/j.oret.2019.12.012DOI Listing
December 2019

Enhanced recovery and accelerated discharge after endoscopic transsphenoidal pituitary surgery: safety, patient feedback, and cost implications.

Acta Neurochir (Wien) 2020 Jun 6;162(6):1281-1286. Epub 2020 Mar 6.

Department of Neurosurgery, Leeds General Infirmary, Leeds, UK.

Background: Enhanced recovery after surgery (ERAS) is a constant motivation. There is growing evidence that an endoscopic (rather than microscopic) transsphenoidal approach to pituitary tumours can play a role, facilitating faster recovery and a commensurate reduction in length of stay (LOS). Reducing LOS is beneficial to both patients and healthcare systems. Read More

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http://dx.doi.org/10.1007/s00701-020-04282-0DOI Listing

In-Office Tympanostomy Tube Placement Using Iontophoresis and Automated Tube Delivery Systems.

OTO Open 2020 Jan-Mar;4(1):2473974X20903125. Epub 2020 Feb 24.

Ear Medical Group, San Antonio, Texas, USA.

Objectives: (1) To evaluate safety, tolerability, and technical success of lidocaine iontophoresis and a tympanostomy tube placement system for adults in an office setting and (2) to meet regulatory evidence requirements for new drugs and devices.

Study Design: Prospective, multicenter, single arm.

Setting: Patients were recruited in 8 community-based practices in the United States between June and September 2017. Read More

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http://dx.doi.org/10.1177/2473974X20903125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040928PMC
February 2020

Effect of Intravenous Lidocaine Infusion on Postoperative Early Recovery Quality in Upper Airway Surgery.

Laryngoscope 2020 Mar 2. Epub 2020 Mar 2.

Department of Anesthesiology, The Affiliated Huaian Hospital of Xuzhou Medical University and Huaian Second People's Hospital, Huaian, China.

Objectives/hypothesis: Systemic infusions of lidocaine have been widely used as perioperative analgesic adjuvants. The aim of this randomized, double-blinded, controlled trial was to investigate the effect of perioperative lidocaine infusion on postoperative early recovery quality in upper airway surgery.

Study Design: Prospective, randomized, double-blinded, placebo-controlled trial. Read More

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http://dx.doi.org/10.1002/lary.28594DOI Listing
March 2020
2.032 Impact Factor

Dihydrotestosterone suppression of proinflammatory gene expression in human meibomian gland epithelial cells.

Ocul Surf 2020 Apr 27;18(2):199-205. Epub 2020 Feb 27.

Schepens Eye Research Institute of Massachusetts Eye and Ear and Department of Ophthalmology, Harvard Medical School, Boston, MA, USA. Electronic address:

Purpose: We discovered that dihydrotestosterone (DHT) decreases the ability of lipopolysaccharide, a bacterial toxin, to stimulate the secretion of leukotriene B4, a potent proinflammatory mediator, by immortalized human meibomian gland epithelial cells (IHMGECs). We hypothesize that this hormone action reflects an androgen suppression of proinflammatory gene activity in these cells. Our goal was to test this hypothesis. Read More

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http://dx.doi.org/10.1016/j.jtos.2020.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195874PMC

Videolaryngoscopy to aid transoesophageal echocardiography probe insertion.

Anaesth Intensive Care 2020 Feb 26:310057X20905608. Epub 2020 Feb 26.

Department of Anaesthesia and Pain Medicine, Royal Perth Hospital, Perth, Australia.

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http://dx.doi.org/10.1177/0310057X20905608DOI Listing
February 2020

Juvenile Hyaline Fibromatosis Management With a Diode Laser: A Rare Case Report.

J Lasers Med Sci 2020 18;11(1):104-107. Epub 2020 Jan 18.

Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Juvenile hyaline fibromatosis (JHF) is an unknown hereditary disorder with variable penetrance. The characterizations of this disease consist of different signs and symptoms such as multiple tumorous (tumor-like) muco-cutaneous proliferation, gingival hypertrophy, perianal lesions, articular contractures, and osteolytic lesions. A 3-year-old girl with numerous painless nodular masses on her gingival, ear and anal areas is presented in this case report. Read More

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http://dx.doi.org/10.15171/jlms.2020.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008743PMC
January 2020

[Plunging ranula presenting as a giant retroauricular mass: A case report].

Beijing Da Xue Xue Bao Yi Xue Ban 2020 Feb;52(1):193-195

Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.

Plunging ranula is rare and manifests as the submandibular or submental cystic mass, without intra-oral abnormality. It usually causes misdiagnosis and malpractice. This article reported a case of plunging ranula that appeared as a massive mass located behind the left ear. Read More

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February 2020

The simultaneous use of three ventilatory techniques to maintain oxygenation in a patient undergoing tracheal laser resection of tumour.

Anaesth Rep 2019 Jul-Dec;7(2):70-72. Epub 2019 Aug 12.

Anaesthesia Royal National Throat, Nose and Ear Hospital UCLH NHS Foundation Trust London UK.

Patients undergoing subglottic airway surgery present a challenge to both anaesthetist and surgeon, and often a balance between surgical access and method of ventilation has to be struck. We report a case in which a 38-year-old female with a large mediastinal mass causing distal tracheal obstruction underwent tracheal laser resection. In order to maintain oxygenation throughout she required simultaneous transnasal humidified rapid-insufflation ventilatory exchange, supraglottic high-frequency jet ventilation and suprastomal manual jet ventilation through her tracheostomy stoma. Read More

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http://dx.doi.org/10.1002/anr3.12021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931295PMC