4,629 results match your criteria Andrologia[Journal]


Does acquired obstructive azoospermia have less impact than congenital azoospermia on ICSI results? Systematic review and meta-analysis.

Andrologia 2021 May 12:e14096. Epub 2021 May 12.

Department of Urology, Centro Universitário FMABC, Santo André, Brazil.

An electronic-based search was performed with MEDLINE bases through PubMed, Cochrane through Central, and Embase until August 2020 for the purpose of evaluating the impact of the aetiology of obstructive azoospermia on ICSI cycles. In the final analysis, there were 15 cohort studies included, comparing a group of patients with acquired azoospermia and others due to congenital bilateral absence of the vas deferens submitted to ICSI. Those 15 articles within 4,480 couples were analysed, and similar fertilisation rate (65. Read More

View Article and Full-Text PDF

Corrigendum.

Authors:

Andrologia 2021 Jun;53(5):e14057

View Article and Full-Text PDF

Infiltration of inflammatory factors induced penile damage in chronic prostatitis.

Andrologia 2021 May 12:e14113. Epub 2021 May 12.

Department of Urology, Shanghai Putuo District People's Hospital, Tongji University, Shanghai, China.

The present study aimed to investigate the mechanism of penile damages in experimental autoimmune prostatitis (EAP) rat models to reveal the potential pathological mechanism of the relationship between CP and penile damages. Sprague-Dawley (SD) rats were administered with different concentrations of prostate tissue homogenate supernatant (PTHS) by multipoint subcutaneous injection to establish EAP models. IHC staining was done to assess the expression of inflammatory cytokines in prostate tissues and the corpus cavernosum of penis. Read More

View Article and Full-Text PDF

Evaluation of the effect of shift working and sleep quality on semen parameters in men attending infertility clinic.

Andrologia 2021 May 12:e14116. Epub 2021 May 12.

Department of Urology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.

We aimed to evaluate the effect of shift work on semen parameters together with the effect of sleep quality in men attending infertility clinic. The participants were divided into two groups as follows: 104 shift worker men (Group 1) and 116 nonshift worker men (Group 2). Groups were compared in terms of semen parameters, Depression Anxiety Stress Scale-21 (DASS-21), and Pittsburg Sleep Quality Index (PSQI) scores. Read More

View Article and Full-Text PDF

An independent indicator of erectile dysfunction is C-reactive protein/albumin ratio.

Andrologia 2021 May 10:e14073. Epub 2021 May 10.

Department of Urology, Van Training and Research Hospital, Edremit, Turkey.

Research has found that, instead of passive lipid-accumulated vascular damage, atherosclerosis which is the primary cause of erectile dysfunction (ED) can be seen as an active inflammatory cycle and that inflammation has a central role in the entire atherosclerotic process. As an inflammatory marker, serum C-reactive protein (CRP)/albumin ratio (CAR) may link to ED and ED severity. The CAR, demographic features and other criteria of 198 patients with ED who visited our outpatient clinic during March 2019-April 2020 were prospectively evaluated. Read More

View Article and Full-Text PDF

A report of pregnancy following ICSI in one of two sisters with familiar primary ciliary dyskinesia.

Andrologia 2021 May 9:e14080. Epub 2021 May 9.

Department of Animal Biotechnology, Reproductive Biomedicine Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, Iran.

Primary ciliary dyskinesia (PCD) is a disorder of structure and function of motor ciliary and dyskinetic activity of ciliary in the fallopian tubes of affected women and could lead to infertility in some cases. In vitro fertilisation (IVF) is a choice of treatment in infertile women with PCD, which could conquer the tubal dysfunction. In this case study, we report a PCD affected woman with infertility who was treated by IVF and pregnancy was achieved but it failed due to the spontaneous abortion. Read More

View Article and Full-Text PDF

Premature Ejaculation, True or False? Clinical evaluation of PE patients with multiple intercourse in one day.

Andrologia 2021 May 8:e14097. Epub 2021 May 8.

Department of Urology, Chinese Academy of Medical Science, Peking Union Medical College, Peking Union Medical College Hospital, Beijing, China.

Clinical characteristics of 216 adult males previously diagnosed with premature ejaculation (PE) were studied. Using a survey questionnaire, characteristics included intravaginal ejaculation latency time (IELT), penile hardness scores and the refractory period (RP). Ninety-four PE patients reported they had experienced vaginal intercourse more than once (2 to 4 times) in one day (~44%). Read More

View Article and Full-Text PDF

Sperm chromatin integrity in a man with macrocephaly syndrome.

Andrologia 2021 May 7:e14100. Epub 2021 May 7.

Department of Animal Biotechnology, Reproductive Biomedicine Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, Iran.

This study reports chromatin status and ICSI outcomes in a case of sperm macrocephaly syndrome(SMS), showing 100% of spermatozoa with abnormal morphology. Percentages of sperm DNA fragmentation for TUNEL (31.7% versus 6. Read More

View Article and Full-Text PDF

Prediction of reproductive function recovery after microsurgical varicocelectomy in men from infertile couples: Clinical and laboratory predictors.

Andrologia 2021 May 7:e14101. Epub 2021 May 7.

Department of Urology and Andrology, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow, Russia.

The objective was to reveal predictors for fertility recovery after varicocelectomy in subfertile men. This retrospective study recruited 93 men with clinical varicocele and pathozoospermia who underwent microsurgical varicocelectomy. Stepwise discriminant analysis was performed to identify predictors of spontaneous pregnancy (SP) after surgery. Read More

View Article and Full-Text PDF

Elevated sperm DNA fragmentation does not predict recurrent implantation failure.

Andrologia 2021 May 7:e14094. Epub 2021 May 7.

Department of Urology, University of Miami Miller School of Medicine, Miami, FL, USA.

In this study, we sought to determine whether sperm DNA fragmentation (DFI%) and high DNA stainability (HDS%) evaluated by sperm chromatin structure assay (SCSA) predict recurrent implantation failure (RIF) or pregnancy rate. A retrospective study was performed of consecutive cycles of ICSI treatment from 2009 to 2018. A total of 386 couples that underwent 1,216 frozen embryo transfer (FET) cycles were analysed. Read More

View Article and Full-Text PDF

An effective method for establishing animal models of azoospermia and oligospermia.

Andrologia 2021 May 7:e14095. Epub 2021 May 7.

Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

The current study aims to develop a validated animal model to predict successful spermatogenesis retrieval in azoospermia and oligospermia men. Thirty-two mice were equally divided into 4 groups: control, scrotal hyperthermia (15 times), scrotal hyperthermia group (10 times), scrotal hyperthermia group (5 times). In the scrotal hyperthermia groups, their scrotum exposed to water at a temperature of 43°C for 20 min every other day. Read More

View Article and Full-Text PDF

Magnetic resonance imaging compared to ultrasound as the preferred method for diagnosing intractable haematospermia.

Andrologia 2021 May 6:e14054. Epub 2021 May 6.

Department of Urology, Institute of Urology, Capital Medical University, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

We aimed to evaluate and compare the clinical diagnostic values of magnetic resonance imaging (MRI) and ultrasound in patients with intractable haematospermia. We performed a retrospective review of 23 patients with intractable haematospermia who were diagnosed with seminal vesicle haematocele and/or calculi by transurethral seminal vesiculoscopy (TSV). Patients' demographics, disease durations, operative times, and MRI and transrectal ultrasound (TRUS) results were recorded. Read More

View Article and Full-Text PDF

The clinical significance of abnormal ejaculation by silodosin. Is it important?

Andrologia 2021 May 5:e14086. Epub 2021 May 5.

Department of Urology, Faculty of Medicine, Trakya University, Edirne, Turkey.

We aimed to evaluate the effect of the abnormal ejaculation (AEj) on patients using silodosin in terms of drug cessation. We also analysed the possible factors that may affect the decisions of patients with AEj to proceed or change their medication. The patients (n = 118) treated with silodosin 8 mg daily were prospectively analysed. Read More

View Article and Full-Text PDF

Predicting risk of erectile dysfunction in patients with nonalcoholic fatty liver disease.

Andrologia 2021 May 5:e14091. Epub 2021 May 5.

Department of Urology, Istanbul University Istanbul School of Medicine, Istanbul, Turkey.

Nonalcoholic fatty liver disease (NAFLD) is one of the risk factors for erectile dysfunction (ED). We aimed to predict the risk of ED in patients with NAFLD. The study included 146 male patients complaining impotence admitted to the urology outpatient clinic aged 24-80 years without a history of alcohol use who underwent abdominal ultrasonography between February 2018 and January 2019. Read More

View Article and Full-Text PDF

Exploring the potentials of some compounds from Garcinia kola seeds towards identification of novel PDE-5 inhibitors in erectile dysfunction therapy.

Andrologia 2021 May 4:e14092. Epub 2021 May 4.

Phytomedicine, Natural Products, Drug and Biochemical Toxicology Group, Department of Biochemistry, Landmark University, Omu Aran, Nigeria.

Erectile dysfunction (ED) is one of the main challenges occurring among men worldwide, and is characterised by trouble getting or keeping steady erection during sexual intercourse. Various drugs like sildenafil, a phosphodiesterase-5 inhibitor (PDE-5) are freely available in the pharmacies, though normally associated with several adverse. This study was designed to assess the molecular relations obtainable between catechin, garcinal, garcinoic acid and d-tocotrienol compounds isolated from Garcinia kola and targeted receptor linked to ED. Read More

View Article and Full-Text PDF

Use of zona pellucida-bound spermatozoa as a natural selection in improvement of ICSI outcomes: A systematic review and meta-analysis.

Andrologia 2021 May 4:e14022. Epub 2021 May 4.

Department of Reproductive Biology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Zona pellucida (ZP)-bound spermatozoa have normal morphology and motility and can enhance the ICSI outcomes. Selection of zona pellucida-bound spermatozoa is recently considered to find functional spermatozoa for ICSI. This study reviewed the efficacy of ZP-bound sperm selection on the ICSI outcomes includes fertilisation rate, embryo quality, embryo transfer rate and clinical pregnancy rate. Read More

View Article and Full-Text PDF

Premature ejaculation and stress.

Andrologia 2021 May 1:e14093. Epub 2021 May 1.

Faculty of Medicine, Department of Sexology, Psychiatric Clinic, Charles University, Pilsen, Czech Republic.

Recent findings indicate that men with premature ejaculation report more frequent sexual problems associated with increased anxiety and interpersonal difficulties. Bearing this in mind, the neuroendocrine changes were examined in men with premature ejaculation and compared to other indicators of stressful experiences to see whether there can be any correlation which could indicate how these factors may contribute to the aetiology of premature ejaculation. Our study comprised 60 male outpatients diagnosed as having secondary premature ejaculation. Read More

View Article and Full-Text PDF

Hyaluronic acid injection in the glans penis for the treatment of refractory premature ejaculation: A prospective, controlled study.

Andrologia 2021 Apr 30:e14084. Epub 2021 Apr 30.

Andrology Department, Cairo University, Cairo, Egypt.

We aimed to demonstrate the safety and efficacy of hyaluronic acid (HA) injection in the glans penis for the treatment of persistent premature ejaculation (PE). Eighty patients with persistent PE were divided equally into two groups. In group A, patients underwent HA injection by four-inlet injection technique, while in group B, patients were subjected to saline injection in glans penis by the same method as a control group. Read More

View Article and Full-Text PDF

Berberine modulates crucial erectogenic biomolecules and alters histological architecture in penile tissues of diabetic rats.

Andrologia 2021 Apr 30:e14074. Epub 2021 Apr 30.

Functional Foods, Nutraceuticals and Phytomedicine Laboratory, Department of Biochemistry, Federal University of Technology, Akure, Nigeria.

Berberine is an isoquinoline alkaloid, found in several plants. Diabetes induces erectile dysfunction (ED) via reduction in some hormones and enzymes implicated in sexual function. This study aimed to investigate the role of berberine on crucial biomolecules linked to penile function in diabetic rats. Read More

View Article and Full-Text PDF

Reply to Letter to the Editor by Derakhshan et al. (2021) 'Vagal nerve stimulation for the treatment of male factor infertility'.

Andrologia 2021 Apr 30:e14069. Epub 2021 Apr 30.

Department of Medical Bioscience, University of the Western Cape, Bellville, South Africa.

View Article and Full-Text PDF

Vagal nerve stimulation for the treatment of male factor infertility.

Andrologia 2021 Apr 30:e14043. Epub 2021 Apr 30.

Department of Diagnostic & Interventional Radiology of New Hospitals LTD, Tbilisi, Georgia.

View Article and Full-Text PDF

The effect of ejaculation time on varicose vein diameter and reflux level.

Andrologia 2021 Apr 28:e14090. Epub 2021 Apr 28.

Department of Urology, Hatay State Hospital, Hatay, Turkey.

The aim of this study was to investigate whether the time interval between ejaculation and scrotal Doppler ultrasonography affects the results of the varicose vein diameter and reflux time. Age, medication use, operation history, physical examination and semen analysis findings, varicose vein diameters and the presence of reflux and reflux time were evaluated prospectively in the patients older than 18 years of age who presented to the urology outpatient clinic with infertility and underwent scrotal Doppler ultrasonography and semen analysis. The time interval between the two scrotal Doppler ultrasonography for semen analysis was noted, the two results were compared. Read More

View Article and Full-Text PDF

The role of sperm in inducing genomic changes in the implantation: An experimental study.

Andrologia 2021 Apr 28:e14077. Epub 2021 Apr 28.

Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.

Endometrial receptivity and implantation are important topics in reproductive sciences. No evidence was found to support sperm involvement in endometrial receptivity and its associated factors. This study aimed to explore the effect of the normal human spermatozoa-endometrium cell interaction in regulating genes in the endometrial receptivity pathway. Read More

View Article and Full-Text PDF

Testosterone levels in COVID-19: More data, but how do we proceed?

Andrologia 2021 Apr 27:e14088. Epub 2021 Apr 27.

First Department of Pediatric Surgery, Pediatric Urology Unit, General Hospital "G. Gennimatas", Aristotle University of Thessaloniki, Thessaloniki, Greece.

View Article and Full-Text PDF

Psychoda albipennis myiasis as a rare cause of erectile dysfunction: A case report.

Andrologia 2021 Apr 27:e14087. Epub 2021 Apr 27.

Department of Urology, Erciyes Kartal Hospital, Kayseri, Turkey.

Urogenital myiasis occurring with the settlement of fly larvae of the order Diptera is facultative and is rarely encountered in humans. This study presents a case of urogenital myiasis caused by Psychoda albipennis in a 42-year-old male patient. The patient was admitted to our hospital with complaints of groin pain, pollakuria and erectile dysfunction and claimed that he saw motile larvae in his urine. Read More

View Article and Full-Text PDF

Paternal trans-fatty acid and vitamin E diet affects rat offspring's semen quality and PPARs expression.

Andrologia 2021 Apr 27:e14082. Epub 2021 Apr 27.

Department of Genetics, Reproductive Biomedicine Research Centre, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.

Trans-fatty acids (TFAs) consumption has created concerns regarding male/female reproductive system. However, the effects of TFA in paternal diet on offspring's reproduction have not been addressed. The purpose of this study is to investigate the effects of rat paternal TFAs and vitamin E consumption on offspring's sperm quality and expression pattern of peroxisome proliferator-activated receptors (PPARs) in testis tissues. Read More

View Article and Full-Text PDF

Role of contrast-enhanced ultrasound with Sonazoid in management of small testicular Leydig cell tumours: A case report with literature review.

Authors:
Min Di Junchang Qin

Andrologia 2021 Apr 27:e14078. Epub 2021 Apr 27.

Ultrasound Department, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Small testicular solid lesions are discovered accidentally due to the extensive use of ultrasound in urology and andrology. Early differentiation between benign and malignant testicular neoplasms is crucial for the determination of treatment options, especially for sub-centimetre lesions. We report a case of a male patient with an incidental discovery of a small testicular lesion on ultrasonography with the chief complaint of left testicular discomfort. Read More

View Article and Full-Text PDF

Relation of glycated hemoglobin and vitamin D deficiency with erectile dysfunction in patients with type 2 diabetes mellitus.

Andrologia 2021 Apr 27:e14076. Epub 2021 Apr 27.

Internal Medicine Department, Health Science University, Prof Dr Cemil Taşcıoğlu City Hospital, Istanbul, Turkey.

Erectile dysfunction (ED) is seen very often in the men with type 2 diabetes mellitus (DM). Due to the ability of vitamin D to reduce endothelial damage and oxidative stress, its role in preventing cardiovascular risk has been demonstrated in some studies. Since ED and cardiovascular disease have common pathogenic mechanisms, many studies have evaluated a possible relationship between vitamin D deficiency and ED. Read More

View Article and Full-Text PDF

Inflammatory factor-based prognostic risk stratification for patients with metastatic castration-resistant prostate cancer treated with docetaxel.

Andrologia 2021 Apr 26:e14064. Epub 2021 Apr 26.

Department of Urology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

To develop a simple inflammatory factor-based prognostic risk stratification system for patients with metastatic castration-resistant prostate cancer (mCRPC) receiving docetaxel as the initial treatment, we reviewed the data of 399 consecutive patients who received first-line docetaxel chemotherapy between January 2013 and June 2019 retrospectively. The optimal cut-off values for the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in terms of survival were calculated by ROC curves. Patients were stratified into favourable (lower NLR and lower PLR), intermediate (higher NLR and lower PLR, or lower NLR and higher PLR) and poor (higher NLR and higher PLR) groups. Read More

View Article and Full-Text PDF

Cyclophosphamide suppresses spermatogenesis in the testis of mice through downregulation of miR-34b and miR-34c.

Andrologia 2021 Apr 26:e14071. Epub 2021 Apr 26.

Department of Histology, Faculty of Medicine Manisa, Celal Bayar University, Manisa, Turkey.

Cyclophosphamide (CP) is commonly used as an anticancer agent but has been associated with high toxicity in several organs, including the testes. In this study, we aimed to evaluate the effects of CP-induced testicular toxicity, using glial cell line-derived neurotrophic factor (GDNF), occludin and transforming growth factor beta 3 (TGF-β3) primary antibodies, and miR-34b and miR-34c expressions. Eighteen young Balb/c male mice were divided into three groups. Read More

View Article and Full-Text PDF