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    24266 results match your criteria Anatomy in Cutaneous Surgery

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    Lateral Femoral Cutaneous Nerve Transposition: Renaissance of an Old Concept in the Light of New Anatomy.
    Clin Anat 2017 Feb 13. Epub 2017 Feb 13.
    Department of Neurological Surgery, University of Wisconsin, 600 Highland Avenue, Madison, Wisconsin, 53792.
    Introduction: Meralgia paresthetica causes pain in the anterolateral thigh. Most surgical procedures involve nerve transection or decompression. We conducted a cadaveric study to determine the feasibility of lateral femoral cutaneous nerve (LFCN) transposition. Read More

    Lateral arm free tissue transfer for parotid reconstruction: A pictorial essay.
    Head Neck 2017 Feb 7. Epub 2017 Feb 7.
    Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, The James Cancer Hospital and Solove Research Institute, Columbus, Ohio.
    Background: The goals of parotid reconstruction are to provide accurate volume reconstruction of the defect while minimizing ptosis, optimize color match to surrounding facial skin, maintain anatomic position of the auricle, and to perform facial nerve rehabilitation in cases in which the facial nerve is removed.

    Methods And Results: For many complex parotid defects, the lateral arm free tissue transfer achieves these reconstructive goals and is the ideal donor site for microvascular reconstruction. In this pictorial essay, we describe the anatomy, harvest, inset, and reconstructive advantages of the lateral arm free tissue transfer in complex parotid reconstruction. Read More

    Bikini versus traditional incision direct anterior approach: is there any difference in soft tissue damage?
    Hip Int 2017 Feb 6. Epub 2017 Feb 6.
    Department of Anatomy and Cell Biology, Western University, Ontario - Canada.
    Introduction: The direct anterior approach for total hip replacements has reported advantages of improved early function and muscle preservation. In an effort to improve healing and cosmesis, a change in the orientation of the incision has been proposed. Traditionally, the skin incision is in-line with the tensor fasciae latae muscle belly. Read More

    Perforator variability in the anterolateral thigh free flap: a systematic review.
    Surg Radiol Anat 2017 Jan 30. Epub 2017 Jan 30.
    Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.
    Objectives: The use of free flaps greatly improves reconstruction options and quality of life for patients undergoing oncological resections. The anterolateral thigh (ALT) free flap is frequently used in the head and neck. The aim of this review was to provide a summary of published evidence assessing perforator anatomy of this flap. Read More

    Experimental Study of the Effects of Nanodispersed Ceria on Wound Repair.
    Bull Exp Biol Med 2017 Jan 14;162(3):395-399. Epub 2017 Jan 14.
    N. S. Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
    We studied the effects of nanodispersed ceria on wound healing in vitro and in vivo. It was found that cerium dioxide stimulated wound healing, which manifested in shrinkage of burn wound area (by 1.5 times) and intensification (by 2. Read More

    Venous drainage of the face.
    J Plast Reconstr Aesthet Surg 2016 Dec 14. Epub 2016 Dec 14.
    Department of Plastic and Reconstructive Surgery, Fujita Health University School of Medicine, Tokyo, Japan.
    The venous anatomy of the face was examined in 12 fresh cadavers. Venograms and arteriovenograms were obtained after the injection of contrast medium. In 8 of the 12 cadavers, a large loop was formed by the facial vein, the supratrochlear vein, and the superficial temporal vein, which became the main trunk vein of the face. Read More

    A stab wound to the axilla illustrating the importance of brachial plexus anatomy in an emergency context: a case report.
    J Med Case Rep 2017 Jan 4;11(1). Epub 2017 Jan 4.
    Anatomy Department, NOVA Medical School, Universidade NOVA de Lisboa, Campo dos Mártires da Pátria, 130, 1169-056, Lisbon, Portugal.
    Background: Although open injuries involving the brachial plexus are relatively uncommon, they can lead to permanent disability and even be life threatening if accompanied by vascular damage. We present a case report of a brachial plexus injury in which the urgency of the situation precluded the use of any ancillary diagnostic examinations and forced a rapid clinical assessment.

    Case Presentation: We report a case of a Portuguese man who had a stabbing injury at the base of his left axilla. Read More

    Endoscopic Anatomy and Features of Anterior Cervical Foraminotomy by Destandau Technique.
    Open Access Maced J Med Sci 2016 Dec 22;4(4):650-653. Epub 2016 Nov 22.
    Department of Neurosurgery, International Neurosciences Institute, Hannover, Germany.
    Background: Minimally invasive spine surgery limits surgical trauma and avoids traditional open surgery so in the majority of cases, recovery is much quicker and patients have less pain after surgery.

    Aim: The authors describe an endoscopic approach to anterior cervical foraminotomy (ACF) by Destandau's method.

    Material And Methods: Anterior cervical foraminotomy by Destandau's method is carried out under general anaesthesia. Read More

    Anatomy of the Platysma Muscle.
    J Craniofac Surg 2016 Dec 23. Epub 2016 Dec 23.
    Department of Plastic Surgery, Inha University School of Medicine, Incheon, Korea.
    The aim of this paper was to review the anatomy the platysma systematically.The term "platysma AND anatomy" was used to search PubMed and Scopus, producing 394 and 214 papers, respectively. After excluding 95 duplicate titles, 513 abstracts and 98 full papers were reviewed. Read More

    Differentiating Intralymphatic Histiocytosis, Intravascular Histiocytosis, and Subtypes of Reactive Angioendotheliomatosis: Review of Clinical and Histologic Features of All Cases Reported to Date.
    Am J Dermatopathol 2017 Jan;39(1):33-39
    *Virginia Tech Carilion Dermatology and Mohs Surgery, Roanoke, VA; and †Cleveland Clinic, Dermatology and Plastic Surgery Institute, Cleveland, OH.
    Reactive angioendotheliomatosis (REA) is a rare benign angioproliferative condition of the skin, which has been noted to occur in patients with a variety of underlying systemic diseases. Histopathologically, this condition is characterized by vascular proliferation, and endothelial cell hyperplasia within the lumina and around dermal vessels, without significant cellular atypia. Since the first case of RAE was reported in 1958, multiple histologic patterns of benign cutaneous vascular proliferations with similar clinical presentations to RAE have been described in the literature and have been proposed as subtypes of the originally described condition. Read More

    Anatomical variability and histological structure of the ulnar nerve in the Guyon's canal.
    Arch Orthop Trauma Surg 2017 Feb 23;137(2):277-283. Epub 2016 Dec 23.
    Department of Anatomy, Jagiellonian University Medical College, 12 Kopernika St, 31-034, Krakow, Poland.
    Objectives: The goal of our study was to analyze the prevalence of variations, branching patterns, and histology of the ulnar nerve (UN) in Guyon's canal to address its importance in hand surgery, particularly decompression of the UN.

    Methods: Fifty fresh cadavers were dissected bilaterally, and the nerve in the area of Guyon's canal was visualized. Samples for histology were also taken and prepared. Read More

    Cutaneous Metastasis: A Study of 138 Cases Diagnosed by Fine-Needle Aspiration Cytology.
    Acta Cytol 2017 22;61(1):47-54. Epub 2016 Dec 22.
    Department of Pathology, Government Medical College and Hospital, Chandigarh, India.
    Background: Cutaneous metastases can occur in a wide variety of internal malignancies and may be the first sign of a clinically silent visceral cancer.

    Study Design: A retrospective analysis was made of 138 cases diagnosed with cutaneous and subcutaneous metastasis on fine-needle aspiration cytology (FNAC). Primary tumors of the skin/subcutis were excluded. Read More

    Non-Thermal Atmospheric Pressure Plasma Efficiently Promotes the Proliferation of Adipose Tissue-Derived Stem Cells by Activating NO-Response Pathways.
    Sci Rep 2016 Dec 19;6:39298. Epub 2016 Dec 19.
    Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
    Non-thermal atmospheric pressure plasma (NTAPP) is defined as a partially ionized gas with electrically charged particles at atmospheric pressure. Our study showed that exposure to NTAPP generated in a helium-based dielectric barrier discharge (DBD) device increased the proliferation of adipose tissue-derived stem cells (ASCs) by 1.57-fold on an average, compared with untreated cells at 72 h after initial NTAPP exposure. Read More

    Heterotopic vascularized lymph node transfer to the medial calf without a skin paddle for restoration of lymphatic function: Proof of concept.
    J Surg Oncol 2017 Jan 15;115(1):90-95. Epub 2016 Dec 15.
    Division of Plastic Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
    Background: The use of heterotopic vascularized lymph node transfer (HVLNT) for the treatment of lower extremity lymphedema is still evolving. Current techniques, either place the lymph nodes in the thigh without a skin paddle or at the ankle requiring an unsightly and often bulky skin paddle for closure. We explored the feasibility of doing a below-knee transfer without a skin paddle using the medial sural vessels as recipient vessels and report our experience in 21 patients. Read More

    Anatomical and Ultrasonic Study Based on Selective Tibial Neurotomy.
    World Neurosurg 2016 Dec 8. Epub 2016 Dec 8.
    Department of the Human Anatomy, Jilin University, Street Xinmin 70, Changchun, China. Electronic address:
    Background: Selective tibial neurotomy (STN) was considered as an effective procedure for the treatment of spastic feet. It's also widely used for treating obese calves in some Asian countries currently. This study aimed to provide morphological measurement data and theoretical support for the operation and intraoperative localization. Read More

    Midface Advancement in a Simple Approach.
    J Craniofac Surg 2017 Jan;28(1):108-112
    *Department of Maxillofacial Surgery, Hospital Sant Joan de Déu, Universitat de Barcelona, Passeig de Sant Joan de Déu, Esplugues de Llobregat †Department of Plastic and Maxillofacial Surgery, Hospital Clinic ‡Human Anatomy Unit, School of Medicine, Universitat de Barcelona, Barcelona, Spain.
    Background: Midface advancement is a keystone intervention in the treatment plan of syndromic hypoplasia of the midface. Although earlier authors had been using a combination of smaller incisions to acquire enough access to perform the different osteotomies, Tessier popularized the bicoronal incision. This approach can be time-consuming however and leaves an ear-to-ear scar. Read More

    Validation and Enhancement of the Clinicopathological Melanoma Nomogram via Incorporation of a Molecular Marker in the Primary Tumor.
    Anticancer Res 2016 12;36(12):6603-6610
    Division of Surgical Oncology, University of Illinois at Chicago Hospital and Health Sciences System, Chicago, IL, U.S.A.
    Background/aim: To validate the melanoma nomogram and improve its function in prediction of nodal dissemination by incorporating a molecular marker in the model. Microphthalmia transcription factor (MITF) is an important regulator of melanocyte homeostasis and differentiation. We have shown that the grade of MITF expression in primary melanoma cells can serve as a predictor of nodal status. Read More

    A Dermal Equivalent Engineered with TGF-β3 Expressing Bone Marrow Stromal Cells and Amniotic Membrane: Cosmetic Healing of Full-Thickness Skin Wounds in Rats.
    Artif Organs 2016 Dec;40(12):E266-E279
    Eposcience Millennium Institute, Tehran, Iran.
    Transforming growth factor beta-3 (TGF-β3) has been shown to decrease scar formation after scheduled topical applications to the cutaneous wounds. This study aimed to continuously deliver TGF-β3, during the early phase of wound healing, by engineering a dermal equivalent (DE) using TGF-β3 expressing bone marrow stromal cells (BM-SCs) and human dehydrated amniotic membrane (hDAM). To engineer a DE, rat BM-SCs were seeded on the hDAM and TGF-β3 was transiently transfected into the BM-SCs using a plasmid vector. Read More

    Security and biomechanical strength of three end-pass configurations for the terminal end of intradermal closures performed with unidirectional barbed suture material in dogs.
    Am J Vet Res 2016 Dec;77(12):1392-1400
    OBJECTIVE To compare security of continuous intradermal suture lines closed by use of barbed suture with 3 end-pass configurations or without an end-pass configuration. SAMPLE 40 full-thickness, 4-cm-long, parasagittal wounds in canine cadavers. PROCEDURES Each continuous intradermal closure was terminated with 1 of 3 end-pass techniques or without an end-pass configuration (control group). Read More

    Pre-expanded Intercostal Perforator Super-Thin Skin Flap.
    Clin Plast Surg 2017 Jan;44(1):73-89
    Department of Plastic and Aesthetic Surgery, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou 510515, P.R. China. Electronic address:
    This article introduces pre-expanded super-thin intercostal perforator flaps, particularly the flap that has a perforator from the first to second intercostal spaces. The key techniques, advantages and disadvantages, and complications and management of this flap are described. At present, the thinnest possible flap is achieved by thinning the pre-expanded flap that has a perforator from the first to second intercostal spaces. Read More

    Pre-expanded Transverse Cervical Artery Perforator Flap.
    Clin Plast Surg 2017 Jan 28;44(1):41-47. Epub 2016 Sep 28.
    Burns Institute of PLA, The First Affiliated Hospital of PLA General Hospital, 51 Fucheng Road, Haidian District, Beijing 100048, P.R. China.
    The face and neck are important areas for function and appearance. High-quality skin flaps should be used to reconstruct defects in the cervicofacial region. This article introduces the pre-expanded transverse cervical artery perforator flap, which can be used for cervicofacial reconstruction after burns, trauma, and tumor resection with excellent results. Read More

    Pre-expanded Super-Thin Skin Perforator Flaps.
    Clin Plast Surg 2017 Jan;44(1):31-40
    Division of Plastic Surgery, University of California Davis Medical Center, 2221 Stockton Boulevard, Suite 2123, Sacramento, CA 95817, USA. Electronic address:
    Patients with severe postburn scar contractures underwent reconstruction of skin defects after scar excision with pre-expanded super-thin skin perforator flaps supplied primarily by perforators via the "bridging effect" from the branches of the adjacent arteries as 2-stage procedures. Pre-expansion is an innovative technique and may improve the anastomoses between subdermal vascular plexuses and extend the supplying area of these vessels to the flap. Such a flap becomes super thin, but with a prefabricated blood supply it can be used for reconstruction of skin defects of the face, neck, or other body part with improved functional and cosmetic outcomes. Read More

    Increasing amount of amyloid are associated with the severity of clinical features in hereditary gelsolin (AGel) amyloidosis.
    Amyloid 2016 Dec 23;23(4):225-233. Epub 2016 Nov 23.
    c Department of Pathology , University of Helsinki and HUSLAB , Helsinki , Finland.
    Background: Patients with hereditary gelsolin (AGel) amyloidosis (HGA) present with hanging skin (cutis laxa) and bilateral cranial neuropathy, and require symptomatic plastic surgery. Our clinical observation of tissue fragility prompted us to design a prospective study.

    Methods: Twenty-nine patients with HGA undergoing surgery were interviewed and clinically examined. Read More

    Cutaneous Metastatic Melanoma Resembling a Halo Nevus, in the Setting of PD-1 Inhibition.
    Am J Dermatopathol 2016 Dec;38(12):e159-e162
    *Department of Anatomical Pathology, PathWest, QEII Medical Centre, Perth, Western Australia, Australia; †School of Pathology and Laboratory Medicine, University of Western Australia, Perth, Western Australia, Australia; ‡Department of Medical Oncology, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia; §School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia; and ¶Margaret River Surgery, Margaret River, Western Australia, Australia.
    Malignant melanoma is a common source of cutaneous metastases and can occasionally adopt a histological appearance which mimics a primary melanocytic lesion, either benign or malignant. The authors describe a case of new cutaneous deposits of metastatic melanoma in a 70-year-old woman with a prominent admixed lymphocytic infiltrate, imparting a striking resemblance to a halo nevus. The authors believe this appearance was a direct reflection of treatment with pembrolizumab, a humanized antibody against the immune checkpoint inhibitor programmed death-1. Read More

    Expression of MicroRNA-301a and its Functional Roles in Malignant Melanoma.
    Cell Physiol Biochem 2016 18;40(1-2):230-244. Epub 2016 Nov 18.
    Department of Plastic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, PR China.
    Background/aims: Although microRNA-301a has been reported to function as an oncogene in many human cancers, the roles of miR-301a in malignant melanoma (MM) is unclear. The present study aims to investigate the functional roles of miR-301a in MM and its possible molecular mechanisms.

    Methods: Quantitative real-time PCR (qRT-PCR) assay was performed to detect the expression of miR-301a in MM tissues, and analyze its correlation with metastasis and prognosis of MM patients. Read More

    Mitotic rate correlates with sentinel lymph node status and outcome in cutaneous melanoma greater than 1 millimeter in thickness: A multi-institutional study of 1524 cases.
    J Am Acad Dermatol 2017 Feb 12;76(2):264-273.e2. Epub 2016 Nov 12.
    Department of Medical Oncology, National Institute for Cancer Research, IRCCS San Martino, Genoa, Italy.
    Background: The 7th edition of the TNM American Joint Committee on Cancer classification incorporates mitotic rate (MR) only for primary cutaneous melanoma (PCM) with Breslow thickness (BT) ≤1 mm.

    Objective: To investigate whether and to what extent MR is able to predict sentinel lymph node (SLN) status and clinical outcome of PCM patients with BT >1 mm.

    Methods: The study included consecutive patients with PCM. Read More

    Anatomical Study of Cutaneous Venous Flow of the Palm.
    Ann Plast Surg 2016 Nov 15. Epub 2016 Nov 15.
    From the *Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, †Department of Biomedical Engineering, Seoul National University College of Medicine, Seoul, Korea; ‡Departments of Anatomy and Plastic and Reconstructive Surgery, School of Medicine, Keio University, Tokyo, Japan; and §Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
    Backgrounds: Various flaps elevated from the palm have been widely used for finger and hand reconstruction. Recently, perforator-based free flaps or venous free flaps have received popularity due to several advantages. The cutaneous venous system has been chosen as the circulatory outlet when designing and harvesting the flap from the palmer area due to the small size and thin nature of the flap. Read More

    Head and neck melanoma (excluding ocular melanoma): United Kingdom National Multidisciplinary Guidelines.
    J Laryngol Otol 2016 May;130(S2):S133-S141
    Northern Centre for Cancer Care and Newcastle University, Freeman Hospital,Newcastle upon Tyne,UK.
    This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the United Kingdom. This paper provides consensus recommendations on the management of melanomas arising in the skin and mucosa of the head and neck region on the basis of current evidence. Recommendations • At-risk individuals should be warned about the correlation between ultraviolet radiation (UVR) exposure and skin cancer, and should be given advice on UVR protection. Read More

    Non-melanoma skin cancer: United Kingdom National Multidisciplinary Guidelines.
    J Laryngol Otol 2016 May;130(S2):S125-S132
    Department of Otolaryngology-Head and Neck Surgery,Manchester Royal Infirmary,Oxford Road,Manchester,UK.
    This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. This paper provides consensus recommendations on the management of cutaneous basal cell carcinoma and squamous cell carcinoma in the head and neck region on the basis of current evidence. Recommendations • Royal College of Pathologists minimum datasets for NMSC should be adhered to in order to improve patient care and help work-force planning in pathology departments. Read More

    Pazopanib in advanced vascular sarcomas: an EORTC Soft Tissue and Bone Sarcoma Group (STBSG) retrospective analysis.
    Acta Oncol 2017 Jan 14;56(1):88-92. Epub 2016 Nov 14.
    o Sarcoma Unit, Interdisciplinary Tumor Center , Mannheim University Medical Center, University of Heidelberg , Mannheim , Germany.
    Background: Pazopanib is a multitargeted tyrosine kinase inhibitor approved for the treatment of patients with selective subtypes of advanced soft tissue sarcoma (STS) who have previously received standard chemotherapy including anthracyclines. Data on the efficacy in vascular sarcomas are limited. The main objective of this study was to investigate the activity of pazopanib in vascular sarcomas. Read More

    Pseudo-Bullous Dermatosis Induced by Topical Anesthetic Agent-Clues to This Localized Toxic Reaction.
    Am J Dermatopathol 2017 Feb;39(2):e19-e22
    *Department of Otolaryngology, Head and Neck Surgery, OhioHealth Doctors Hospital, Columbus, OH; †Division of Dermatology, Baylor University Medical Center, Dallas, TX; ‡Department of Dermatology, Walter Reed National Military Medical Center, Bethesda, MD; and §Ackerman Academy of Dermatopathology, New York, NY.
    Eutectic mixture of 2.5% lidocaine and 2.5% prilocaine (EMLA AstraZeneca, DE) is a widely used topical anesthetic cream for preprocedural cutaneous analgesia. Read More

    Metastatic Basosquamous Carcinoma: Report of Two Cases and Clinicopathological Considerations.
    Int J Surg Pathol 2016 Dec 27;24(8):726-732. Epub 2016 May 27.
    Department of Maxillofacial Surgery, University of Verona, Verona, Italy.
    Basosquamous carcinoma is a rare cutaneous tumor considered by some authors as an aggressive type of basal cell carcinoma having a propensity for local recurrence and a potential risk for regional and distant metastatic spread. Herein we present 2 cases of basosquamous carcinoma of head and neck region, with metastatic spread to parotid gland (case 1) and to cervical nodes (case 2). Both patients had recurrence 2 years after initial treatment of the primary lesion (first patient: surgery; second patient: radiotherapy) and at the same time developed regional metastases. Read More

    Intracortical microstimulation of human somatosensory cortex.
    Sci Transl Med 2016 Oct 13;8(361):361ra141. Epub 2016 Oct 13.
    Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA.
    Intracortical microstimulation of the somatosensory cortex offers the potential for creating a sensory neuroprosthesis to restore tactile sensation. Whereas animal studies have suggested that both cutaneous and proprioceptive percepts can be evoked using this approach, the perceptual quality of the stimuli cannot be measured in these experiments. We show that microstimulation within the hand area of the somatosensory cortex of a person with long-term spinal cord injury evokes tactile sensations perceived as originating from locations on the hand and that cortical stimulation sites are organized according to expected somatotopic principles. Read More

    Detailed vascular anatomy of the medial femoral condyle and the significance of its use as a free flap.
    J Plast Reconstr Aesthet Surg 2016 Dec 5;69(12):1683-1689. Epub 2016 Oct 5.
    Department of Oral and Maxillofacial Surgery, Paracelsus Medical University of Salzburg, Austria.
    Objective: The aim of this study is to provide detailed information on the arterial variations of the descending geniculate artery (DGA) for the harvest of a cortico-periostal flap from the medial femoral condyle and a fascio-cutaneous perforator flap with its respective pedicles.

    Material And Methods: A total of 50 lower limbs from embalmed cadavers were dissected. The distribution pattern, length, and diameter of the DGA, saphenous artery (SA), muscular, periostal, and articular branches, and their concomitant veins were measured and evaluated. Read More

    Primary cutaneous B-cell lymphoma other than marginal zone: clinicopathologic analysis of 161 cases: Comparison with current classification and definition of prognostic markers.
    Cancer Med 2016 Oct 26;5(10):2740-2755. Epub 2016 Sep 26.
    Unit of Anatomic Pathology, Department of Molecular Medicine, University of Pavia and Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
    Categorization of primary cutaneous B-cell lymphomas (PCBCL) other than marginal zone (MZL) represents a diagnostic challenge with relevant prognostic implications. The 2008 WHO lymphoma classification recognizes only primary cutaneous follicular center cell lymphoma (PCFCCL) and primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT), whereas the previous 2005 WHO/EORTC classification also included an intermediate form, namely PCDLBCL, other. We conducted a retrospective, multicentric, consensus-based revision of the clinicopathologic characteristics of 161 cases of PCBCL other than MZL. Read More

    A hair on the tongue.
    Rev Stomatol Chir Maxillofac Chir Orale 2016 Nov 24;117(5):357-358. Epub 2016 May 24.
    AP-HP, Pierre et Marie Curie - Sorbonne University, Pitié-Salpêtrière Hospital, Maxillo-Facial Surgery (Pr Goudot), 47-83, boulevard de l'Hôpital, Paris, France.
    Introduction: Human hairs are generally localized on the cutaneous part of the head, neck, torso, armpits, pubis and limbs. Sometimes it can be found in an unusual localization and is then called heterotopic.

    Observation: A 30-year-old man presented with a hair in the middle of the dorsum of the tongue. Read More

    Response of extensive breast cancer skin metastases to rechallenge with trastuzumab together with low-dose chemotherapy and insulin.
    Tumori 2016 Nov 11;102(Suppl. 2). Epub 2016 Nov 11.
     Medical Oncology Division and Breast Unit, Antonio Perrino Hospital, Brindisi - Italy.
    Introduction: Cutaneous metastasis occurs in about 29% of breast cancer patients and has a deep impact on patient quality of life.

    Methods: A 60-year-old woman with cutaneous metastases from heavily pretreated HER2-positive breast cancer received CMFVP (oral cyclophosphamide 100 mg daily; oral prednisone 12.5 mg daily for 2 weeks, then 7. Read More

    Do demographics and tumour-related factors affect nodal yield at neck dissection? A retrospective cohort study.
    J Laryngol Otol 2017 Jan 27;131(S1):S36-S40. Epub 2016 Oct 27.
    Department of Otolaryngology and Head and Neck Surgery,Monash Health,Melbourne,Australia.
    Background: Nodal metastasis is an important prognostic factor in head and neck squamous cell carcinoma. This study aimed to determine the average nodal basin yield per level of neck dissection, and to investigate if age, gender, body mass index, tumour size, depth of tumour invasion and p16 status influence nodal yield.

    Method: A retrospective review of 185 patients with head and neck squamous cell carcinoma generated 240 neck dissection specimens. Read More

    Retrospective multicenter evaluation of patients diagnosed with mucosal melanoma: a study of Anatolian Society of Medical Oncology.
    Tumour Biol 2016 Sep 12;37(9):12033-12038. Epub 2016 May 12.
    Department of Medical Oncology, Faculty of Medicine, Bezmi Alem Vakif University, Istanbul, Turkey.
    Mucosal melanoma (MM) is a rare type of cancer that differs significantly from cutaneous melanoma. In this study, we aimed to evaluate clinical and demographical characteristics, prognoses and factors influencing survival, treatment alternatives, and features of different subtypes of the patients. The patients were followed up with and treated in different centers due to their diagnoses of MM. Read More

    Reconstruction of totally degloved fingers: a novel application of the bilobed spiraled innervated radial artery superficial palmar branch perforator flap design provides for primary donor-site closure.
    Surg Radiol Anat 2016 Oct 21. Epub 2016 Oct 21.
    Department of Orthopedic Surgery, Division of Plastic and Hand Surgery, The Second Affiliated Hospital of Wenzhou Medical College, Wenzhou, China.
    Introduction: To investigate the results of resurfacing completely degloved digits using bilobed innervated radial artery superficial palmar branch (RASPB) perforator flap in a spiral fashion.

    Methods: A detailed anatomic study on 30 adult fresh frozen cadavers preinjected with silicone rubber compound to demarcate arterial anatomy documented locations, numbers, and diameters of arteries and skin perforators with surrounding nerves. The flap-raising procedure was performed using four fresh cadaver specimen. Read More

    A prognostic model for resectable soft tissue and cutaneous angiosarcoma.
    J Surg Oncol 2016 Oct 4;114(5):557-563. Epub 2016 Jul 4.
    Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
    Background: Angiosarcoma is an aggressive tumor rising in incidence from use of therapeutic radiation. Because of its relative rarity, prognostic factors have not been clearly delineated.

    Methods: Patients who underwent resection of localized angiosarcoma from 2002 to 2012 were identified using the National Cancer Data Base. Read More

    Primary Cutaneous Mammary Analog Secretory Carcinoma With ETV6-NTRK3 Translocation.
    Am J Dermatopathol 2016 Nov;38(11):842-845
    Departments of *Dermatology, and †Pathology, Northwestern University, Chicago, IL; and ‡Forefront Dermatology, Manitowoc, WI.
    Mammary analog secretory carcinoma (MASC) is a recently described tumor of the salivary glands named for its morphological and molecular similarity to secretory carcinoma of the breast. Many primary carcinomas arising from the adnexal glands also share similar morphology to those arising from the breast. Brandt et al first described primary cutaneous MASC in 2009 and since then only 2 other cases have been reported. Read More

    High Relative Expression of Pannexin 3 (PANX3) in an Axillary Sweat Gland Carcinoma With Osteosarcomatous Transformation.
    Am J Dermatopathol 2016 Nov;38(11):846-851
    *Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN; Departments of †Pathology, ‡Dermatology, and §Radiology, University of Arkansas for Medical Sciences, Little Rock, AR; ¶Division of Hematology/Oncology, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR; Departments of ‖Orthopedic Surgery and **Pathology, University of Arkansas for Medical Sciences, Little Rock, AR.
    Primary cutaneous sweat gland carcinomas (SGCs) are rare tumors that commonly involve axillae, have a high local recurrence rate, and rarely show sarcomatoid transformation. A 68-year-old man presented with rapid enlargement of a previously stable, asymptomatic pea-sized nodule in the left axilla. Initial excision (with positive surgical margins) at another institution showed characteristic histologic features of a high-grade osteosarcoma and molecular analysis using a 92-gene real-time quantitative reverse transcription-polymerase chain reaction assay confirmed a diagnosis of osteosarcoma with 96% certainty. Read More

    Cutaneous Osteoblastic Osteosarcoma: Report of 2 New Cases Integrated With SATB2 Immunohistochemistry and Review of the Literature.
    Am J Dermatopathol 2016 Nov;38(11):824-831
    *Department of Pathology, Policlinico di Cattinara, University of Trieste, Trieste, Italy; †Department of Pathology, General Hospital S. Maria della Misericordia, Udine, Italy; ‡Department of Pathology, University Medical Centre Maribor, Maribor, Slovenia; and §Institute of Pathology, Medical Faculty University of Ljubljana, Ljubljana, Slovenia.
    We report 2 cases of primary dermal osteosarcoma. The patients were an 88-year-old man and a 72-year-old man complaining of masses occurring in the ear pavilion and the palm, deemed suspicious for basal cell carcinoma and metastatic colonic carcinoma, and were treated by resection. Microscopically, both featured a dermal lesion mostly composed of atypical spindle cells within a fibrous to hyaline matrix often showing mineralization. Read More

    Reexcision Perineural Invasion and Epithelial Sheath Neuroma Possibly on a Spectrum of Postinjury Reactive Hyperplasia Mediated by IL-6.
    Am J Dermatopathol 2017 Jan;39(1):49-52
    *Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY; †Ohio State University Comprehensive Cancer Center, Columbus, OH; and ‡NYC Dermatology and Cosmetic Center, New York, NY.
    Epithelial sheath neuroma is a rarely recognized but established entity in the medical literature. First described in 2000 by Requena et al, there have only been 7 published cases to date, mostly in female patients and presenting as symptomatic solitary lesions on the back without a known history of trauma. In 2006, Beer et al described and reviewed a dozen cases in which epithelial sheath neuroma-like features were seen in the advent of a surgical procedure, which was termed "re-excision perineural invasion" and attributed to possible eccrine duct implantation during surgery. Read More

    Sentinel lymph node biopsy for high-risk cutaneous squamous cell carcinoma: Analysis of recurrence-free survival.
    Medicina (Kaunas) 2016 28;52(5):276-282. Epub 2016 Sep 28.
    Department of Plastic and Reconstructive Surgery, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
    Background And Aim: Cutaneous squamous cell carcinoma (CSCC) is a malignant epithelial cell tumor. CSCC has a tendency to spread via lymphogenic pathway. Metastases are found in 2%-6% of cases. Read More

    Different contributions of angiostatin and endostatin in angiogenesis impairment in systemic sclerosis: a cohort study.
    Clin Exp Rheumatol 2016 Sep-Oct;34 Suppl 100(5):37-42. Epub 2016 Feb 16.
    Clinical Immunology Unit, Dept.
 of Medicine, Hosp. de Santo António (HSA), Centro Hospitalar do Porto (CHP); and Multidisciplinary Unit for Biomedical Investigation (UMIB), Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Univ. do Porto, Portugal.
    Objectives: To determine the concentrations of circulating endostatin and angiostatin in patients with systemic sclerosis (SSc) and to assess its relationship to disease subsets, evolution phase, organ involvement and nailfold capillaroscopic changes.

    Methods: Endostatin and angiostatin serum levels were measured by ELISA in a cohort of 57 patients with SSc, and correlated with disease subsets, evolution phase, organ involvement and nailfold capillaroscopic changes.

    Results: Endostatin and angiostatin serum levels were significantly higher in patients with SSc than in healthy controls. Read More

    Anatomy of Forehead, Glabellar, Nasal and Orbital Muscles, and Their Correlation with Distinctive Patterns of Skin Lines on the Upper Third of the Face: Reviewing Concepts.
    Aesthetic Plast Surg 2016 Dec 14;40(6):962-971. Epub 2016 Oct 14.
    Division of Plastic Surgery at the General Hospital São Luiz, ACA - Institute of Assistance in Plastic Surgery of São Paulo, Rua Afonso de Freitas, 641, São Paulo, SP, 04006-052, Brazil.
    Background: The purpose of this study is to establish a relationship between the skin lines on the upper third of the face in cadavers, which represent the muscle activity in life and the skin lines achieved by voluntary contraction of the forehead, glabellar, and orbital muscles in patients.

    Methods: Anatomical dissection of fresh cadavers was performed in 20 fresh cadavers, 11 females and 9 males, with ages ranging from 53 to 77 years. Subcutaneous dissection identified the muscle shape and the continuity of the fibers of the eyebrow elevator and depress muscles. Read More

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