145,345 results match your criteria Anatomical record Hoboken N.J. : 2007[Journal]


Optimising the biocompatibility of 3D printed photopolymer constructs in vitro and in vivo.

Biomed Mater 2019 Feb 22. Epub 2019 Feb 22.

Department of Surgery, University of Melbourne Faculty of Medicine Dentistry and Health Sciences, Melbourne, Victoria, AUSTRALIA.

3D printing is a rapid and accessible fabrication technology that engenders creative custom design solutions for cell scaffolds, perfusion systems and cell culture systems for tissue engineering. Critical to its success is the biocompatibility of the materials used, which should allow long-term tissue culture without affecting cell viability or inducing an inflammatory response for in vitro and in vivo applications. Polyjet 3D printers offer arguably the highest resolution with the fewest design constraints of any commercially available 3D printing systems. Read More

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http://dx.doi.org/10.1088/1748-605X/ab09c4DOI Listing
February 2019

Surgical Results of Carotid Endarterectomy for Twisted Carotid Bifurcation.

World Neurosurg 2019 Feb 19. Epub 2019 Feb 19.

Department of Neurosurgery, Juntendo University Nerima Hospital, Tokyo, Japan.

Background: The internal carotid artery (ICA) is normally positioned posterolateral to the external carotid artery (ECA) at the carotid bifurcation. An anatomical variation with the ICA positioned medial to the ECA, the so-called twisted carotid bifurcation, is sometimes encountered in patients undergoing carotid endarterectomy (CEA). Little is known about the twisted carotid bifurcation or the implications for CEA. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.282DOI Listing
February 2019

Welfare assessment of novel on-farm killing methods for poultry.

PLoS One 2019 22;14(2):e0212872. Epub 2019 Feb 22.

Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, United Kingdom.

There is a need for novel mechanical devices for dispatching poultry on farm following the introduction of EU Regulation (EC) no. 1099/2009 On the Protection of Animals at the Time of Killing. We examined three novel mechanical killing devices: Modified Armadillo, Modified Rabbit Zinger, a novel mechanical cervical dislocation device; and traditional manual cervical dislocation. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212872PLOS
February 2019

Automatic classification of tissues on pelvic MRI based on relaxation times and support vector machine.

PLoS One 2019 22;14(2):e0211944. Epub 2019 Feb 22.

Le2i, Université Bourgogne Franche-Comte, Dijon, France.

Tissue segmentation and classification in MRI is a challenging task due to a lack of signal intensity standardization. MRI signal is dependent on the acquisition protocol, the coil profile, the scanner type, etc. While we can compute quantitative physical tissue properties independent of the hardware and the sequence parameters, it is still difficult to leverage these physical properties to segment and classify pelvic tissues. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211944PLOS
February 2019

Implications of Classification of Os Trigonum: A Study Based on Computed Tomography Three-Dimensional Imaging.

Med Sci Monit 2019 Feb 22;25:1423-1428. Epub 2019 Feb 22.

Department of Orthopedic, Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, China (mainland).

BACKGROUND The os trigonum is an accessory bone that is not fully fused with the talus during secondary ossification, and is one of the risk factors of posterior malleolus impact syndrome. The purpose of this study was to classify the os trigonum and to guide the diagnosis and treatment of related clinical diseases. MATERIAL AND METHODS Ankle computed tomography (CT) scans of 586 Chinese patients between October 2014 and October 2018 were reviewed. Read More

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http://dx.doi.org/10.12659/MSM.914485DOI Listing
February 2019

Blunt cardiac injury: emergency department diagnosis and management.

Emerg Med Pract 2019 Mar 1;21(3):1-20. Epub 2019 Mar 1.

Associate Professor, Residency Program Director, SUNY Upstate Medical University, Syracuse, NY.

Blunt cardiac injury describes a range of cardiac injury patterns resulting from blunt force trauma to the chest. Due to the multitude of potential anatomical injuries blunt force trauma can cause, the clinical manifestations may range from simple ectopic beats to fulminant cardiac failure and death. Because there is no definitive, gold-standard diagnostic test for cardiac injury, the emergency clinician must utilize an enhanced index of suspicion in the clinical setting combined with an evidence-based diagnostic testing approach in order to arrive at the diagnosis. Read More

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Validation and iteration of CT perfusion defined malignant profile thresholds for acute ischemic stroke.

Int J Stroke 2019 Feb 22:1747493019832987. Epub 2019 Feb 22.

1 Department of Neurology, University of California, San Francisco, CA, USA.

Background: Malignant profile computed tomography perfusion (CTP) lesions are associated with poor outcomes after administration of intravenous tissue-plasminogen activator (IV-tPA) for ischemic stroke.

Aims: To determine whether published CTP-based lesion thresholds predictive of poor outcomes in a predominantly 8 cm of CTP anatomic coverage cohort would predict poor outcomes in an independent 4 cm of CTP anatomic coverage cohort and to generate optimized 4 cm CTP thresholds.

Methods: Ischemic stroke patients with baseline CTP imaging with 4 cm of anatomic coverage before receiving IV-tPA at a single institution were retrospectively studied. Read More

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http://dx.doi.org/10.1177/1747493019832987DOI Listing
February 2019

Specific brain morphometric changes in spinal cord injury: a voxel-based meta-analysis of white and grey matter volume.

J Neurotrauma 2019 Feb 22. Epub 2019 Feb 22.

105# jiefang roadJinan, Shandong, China , 250013 ;

We want to investigate degenerative changes of white matter volume (WMV) and grey matter volume (GMV) in individuals after a spinal cord injury (SCI). Published studies of whole-brain voxel-based morphometry (VBM) comparing SCI patients with controls published between 2006 and March 1st, 2018 were collected by searching PubMed, Web of Science, and EMBASE databases. Voxel-wise meta-analyses of GMV and WMV differences between SCI patients and controls were performed separately using seed-based d mapping. Read More

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http://dx.doi.org/10.1089/neu.2018.6205DOI Listing
February 2019

Anatomical study of presigmoid-retrolabyrinthine approach based on temporal bone high-resolution CT.

Acta Otolaryngol 2019 Feb 22:1-5. Epub 2019 Feb 22.

b Department of Radiology , Beijing Tongren Hospital, Affiliate of Capital Medical , Beijing , China.

Background: The surgical approach of acoustic neuroma includes translabyrinthine, transcranial fossa, suboccipital retrosigmoid sinus, and presigmoid retrolabyrinthine approach. Aims/Objective: To provide the anatomical basis for the surgical selection of presigmoid retrolabyrinthine approach by measuring the anatomical parameters of retrolabyrinthine space of the petrous bone by high-resolution CT.

Material And Methods: A retrospective study of 208 high-resolution CT (HRCT) images of 104 patients examined in our hospital were analyzed retrospectively. Read More

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http://dx.doi.org/10.1080/00016489.2018.1550585DOI Listing
February 2019

Emerging patterns in HIV-1 gp120 variable domains in anatomical tissues in the absence of a plasma viral load.

AIDS Res Hum Retroviruses 2019 Feb 22. Epub 2019 Feb 22.

The AIDS and Cancer Specimen Resource , University of California, San Francisco , San Francisco, United States , 94121.

The HIV envelope protein contains five hypervariable domains (V1-V5) that are fundamental for cell entry. We contrasted modifications in the variable domains derived from a panel of 24 tissues from 7 subjects with no measurable plasma viral load (NPVL) to variable domains from 76 tissues from 15 subjects who had a detectable plasma viral load (PVL) at death. NPVL subject's V1 and V2 domains were usually highly length variable, whereas length variation in PVL sequences was more conserved. Read More

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http://dx.doi.org/10.1089/AID.2018.0267DOI Listing
February 2019

Use of prophylactic silicone adhesive dressings for maintaining skin integrity in intensive care unit patients: A randomised controlled trial.

Int Wound J 2019 Mar;16 Suppl 1:36-42

Biologics Division, Biopharmaceuticals and Herbal Medicine Evaluation Department, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju, Republic of Korea.

The aims of this randomised controlled study were to determine whether the application of silicone adhesive dressings with standard preventive care would reduce the impairment of skin integrity and to evaluate the subepidermal moisture (SEM) value in anatomical locations to predict impairment of skin integrity. Of the 71 intensive care unit patients enrolled, 35 and 31 were randomly assigned to the intervention and control groups, respectively. The SEM value was measured at each site (the coccyx, sacrum, and both buttocks) repeatedly three times at every dressing change. Read More

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http://dx.doi.org/10.1111/iwj.13028DOI Listing

The Spectrum of Learning and Teaching: The Impact of a Fourth-Year Anatomy Course on Medical Student Knowledge and Confidence.

Anat Sci Educ 2019 Feb 22. Epub 2019 Feb 22.

Department of Physical Therapy, Northeastern University, Boston, Massachusetts.

There is growing demand from accrediting agencies for improved basic science integration into fourth-year medical curricula and inculcation of medical students with teaching skills. The objective of this study was to determine the effectiveness of a fourth-year medical school elective course focused on teaching gross anatomy on anatomical knowledge and teaching confidence. Fourth-year medical student "teacher" participants' gross anatomy knowledge was assessed before and after the course. Read More

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http://dx.doi.org/10.1002/ase.1872DOI Listing
February 2019

Tumor-derived exosomes: Implication in angiogenesis and antiangiogenesis cancer therapy.

J Cell Physiol 2019 Feb 22. Epub 2019 Feb 22.

Department of Clinical Genetics, Linköping University Hospital, Linköping, Sweden.

Tumor cells utilize different strategies to communicate with neighboring tissues for facilitating tumor progression and invasion, one of these strategies has been shown to be the release of exosomes. Exosomes are small nanovesicles secreted by all kind of cells in the body, especially cancer cells, and mediate cell to cell communications. Exosomes play an important role in cancer invasiveness by harboring various cargoes that could accelerate angiogenesis. Read More

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http://dx.doi.org/10.1002/jcp.28374DOI Listing
February 2019

Anatomical Sciences in Chiropractic Education: A survey of Chiropractic Programs in Australia.

Anat Sci Educ 2019 Feb 21. Epub 2019 Feb 21.

Department of Anatomy, School of Medical Sciences, Faculty of Medicine, The University of New South Wales, Sydney, New South Wales, Australia.

Human anatomy knowledge is a core requirement for all health care clinicians. There is a paucity of information relating to anatomy content and delivery in Australian chiropractic programs. The aim of this study was to describe anatomy teaching in Australian chiropractic programs, utilizing a survey which was distributed to all four programs, requesting information on: anatomy program structure, delivery methods, assessment, teaching resources, and academic staff profile at their institution. Read More

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http://dx.doi.org/10.1002/ase.1871DOI Listing
February 2019

Anatomical analysis of zygomatic bone in ectodermal dysplasia patients with oligodontia.

Clin Implant Dent Relat Res 2019 Feb 21. Epub 2019 Feb 21.

Second Dental Clinic, Department of Oral Implantology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University, School of Medicine, National Clinical Research Center for Oral Disease, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China.

Background: Abnormalities of some facial bones derived from the ectomesenchyme have been found in ectodermal dysplasia (ED) patients, but the characteristics of the zygoma are unknown.

Purpose: Comparison between ED patients and normal individuals to understand the anatomical features of the zygoma in ED patients.

Materials And Methods: Thirty patients diagnosed with ED based on clinical features and/or gene sequence tests and 80 normal individuals were recruited from 2016 to 2018. Read More

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http://dx.doi.org/10.1111/cid.12731DOI Listing
February 2019

Robust cerebrovascular blood velocity and flow rate estimation from 4D CTA.

Med Phys 2019 Feb 22. Epub 2019 Feb 22.

Departement of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.

Purpose: Blood velocity and flow rate information may be helpful for a wide variety of applications, but it often requires separate acquisitions. The dynamic information combined with the high spatial resolution of 4D-CTA offers the possibility to quantify blood flow simultaneous to vascular anatomy.

Methods: A 4D-CTA clinical protocol with a novel dedicated post-processing were validated in vitro in a patient-specific model, and tested in a pilot study of 6 patients. Read More

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http://dx.doi.org/10.1002/mp.13454DOI Listing
February 2019

Does fertilisation explain the extraordinary hydraulic behaviour of apple trees?

J Exp Bot 2019 Feb 22. Epub 2019 Feb 22.

University of Innsbruck, Institute of Botany, Sternwartestrasse, Innsbruck, Austria.

Fertilisation of woody plants plays a central role in agriculture and forestry, but little is known about how plant water relations are thereby affected. Here we investigated the impact of fertilisation on tree hydraulics, xylem and pit anatomy in the high-yield apple cultivars Golden and Red Delicious. In fertilised trees of Golden Delicious specific hydraulic conductivity of branch xylem, hydraulic conductance of the root system and maximum stomatal conductance increased considerably. Read More

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http://dx.doi.org/10.1093/jxb/erz070DOI Listing
February 2019

Split-mouth Randomised Clinical Trial on the Efficacy of GIC Sealant on Occlusal Surfaces of Primary Second Molar.

Oral Health Prev Dent 2019 ;17(1):17-24

Purpose: To evaluate the clinical performance of high viscosity GIC sealant applied with or without additional light curing in children with early childhood caries (ECC).

Materials And Methods: A split-mouth clinical trial was conducted in a total of 111 3- to 5-year-old children with ECC. 180 pairs of non-carious primary second molars were selected and divided into two groups: study and control. Read More

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http://dx.doi.org/10.3290/j.ohpd.a41979DOI Listing
January 2019

Postoperative ascending aortic gigantic pseudoaneurysm: Endovascular treatment with the use of a septal occluder plug.

Interv Med Appl Sci 2018 Dec;10(4):213-215

Department of Radiology, Sant'Andrea University Hospital La Sapienza, Rome, Italy.

A rare postoperative complication of aortic root replacement is pseudoaneurysm formation. Surgical repair may be rather challenging particularly in patients who are elder and with significant comorbidities. Endovascular approach may also be technically demanding, given the high blood velocity and the anatomical challenges of the area of the aortic root and the ascending aorta. Read More

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http://dx.doi.org/10.1556/1646.10.2018.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376348PMC
December 2018

Haploinsufficiency of autism causative gene impairs olfactory discrimination and neuronal activation of the olfactory system in mice.

Mol Autism 2019 11;10. Epub 2019 Feb 11.

1Institute of Molecular Biology, Academia Sinica, 128, Academia Rd., Sec. 2, Taipei, 11529 Taiwan.

Background: Autism spectrum disorders (ASD) exhibit two clusters of core symptoms, i.e., social and communication impairment, and repetitive behaviors and sensory abnormalities. Read More

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http://dx.doi.org/10.1186/s13229-019-0257-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371489PMC
February 2019

The Dynamic Oval Pupil.

Front Neurol 2019 7;10:75. Epub 2019 Feb 7.

Department of Surgery (Neurosurgery), Jersey Shore University Medical Center, Neptune, NJ, United States.

The dynamic oval pupil is defined and its distinction from corectopia, as well as their different clinical significance is proposed. A literature search for instances presenting this condition yielded only 20 such cases with enough clinical data. A review of these cases allows us to draw some tentative conclusions regarding the most likely anatomical location for its causative lesion and the pathophysiological mechanism responsible for its occurrence. Read More

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http://dx.doi.org/10.3389/fneur.2019.00075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374288PMC
February 2019

Gender Identification of Human Cortical 3-D Morphology Using Hierarchical Sparsity.

Front Hum Neurosci 2019 7;13:29. Epub 2019 Feb 7.

College of Mechatronics and Automation, National University of Defense Technology, Changsha, China.

Difference exists widely in cognition, behavior and psychopathology between males and females, while the underlying neurobiology is still unclear. As brain structure is the fundament of its function, getting insight into structural brain may help us to better understand the functional mechanism of gender difference. Previous structural studies of gender difference in Magnetic Resonance Imaging (MRI) usually focused on gray matter (GM) concentration and structural connectivity (SC), leaving cortical morphology not characterized properly. Read More

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http://dx.doi.org/10.3389/fnhum.2019.00029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374327PMC
February 2019

Covariance statistics and network analysis of brain PET imaging studies.

Sci Rep 2019 Feb 21;9(1):2496. Epub 2019 Feb 21.

Department of Neuroimaging, IoPPN, King's College London, London, United Kingdom.

The analysis of structural and functional neuroimaging data using graph theory has increasingly become a popular approach for visualising and understanding anatomical and functional relationships between different cerebral areas. In this work we applied a network-based approach for brain PET studies using population-based covariance matrices, with the aim to explore topological tracer kinetic differences in cross-sectional investigations. Simulations, test-retest studies and applications to cross-sectional datasets from three different tracers ([F]FDG, [F]FDOPA and [C]SB217045) and more than 400 PET scans were investigated to assess the applicability of the methodology in healthy controls and patients. Read More

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http://dx.doi.org/10.1038/s41598-019-39005-8DOI Listing
February 2019

Left main bronchus as a guide for individualized transseptal puncture using a conventional fluoroscopic approach in cryoballoon ablation of atrial fibrillation.

Anatol J Cardiol 2019 Dec 31. Epub 2019 Dec 31.

Department of Cardiology, Xijing Hospital, Fourth Military Medical University (Air Force Medical University); Xi'an-China.

Objective: Although imaging modalities, such as transesophageal and intracardiac echocardiography, have helped to improve the safety of atrial transseptal puncture (TSP), fluoroscopy is still traditionally and widely used in TSP. The aim of the present study was to evaluate an individual knack for TSP during cryoballoon ablation of atrial fibrillation (AF) under fluoroscopy.

Methods: Through the prospective study of 72 cases of patients with paroxysmal or persistent AF admitted for cryoablation in our center, 46 cases using a puncture site toward the bifurcation of the left main bronchus (LMB group) and 26 cases using an anterior-inferior puncture site (AI group) were included in the study. Read More

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http://dx.doi.org/10.14744/AnatolJCardiol.2018.08566DOI Listing
December 2019

Multiple Pathways Act Together To Establish Asymmetry of the Ventral Nerve Cord in .

Genetics 2019 Feb 21. Epub 2019 Feb 21.

Simon Fraser University

The central nervous system of most animals is bilaterally symmetrical. Closer observation often reveals some functional or anatomical left-right asymmetries. In the nematode the most obvious asymmetry in the nervous system is found in the ventral nerve cord (VNC), where most axons are in the right axon tract. Read More

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http://dx.doi.org/10.1534/genetics.119.301999DOI Listing
February 2019

Chronic low back pain: Relevance of a new classification based on the injury pattern.

Orthop Traumatol Surg Res 2019 Feb 18. Epub 2019 Feb 18.

Société française de chirurgie du rachis (SFCR), 56, rue Boissonade, 75014 Paris, France.

Background: The objectives of this study were to define the role for surgery in the treatment of chronic low back pain (cLBP) and to develop a new classification of cLBP based on the pattern of injury.

Hypothesis: Surgery may benefit patients with cLBP, and a new classification based on the injury pattern may be of interest.

Method: A systematic literature review was performed by searching Medline, the Cochrane Library, the French public health database (Banque de Données en Santé Publique), Science Direct, and the National Guideline Clearinghouse. Read More

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http://dx.doi.org/10.1016/j.otsr.2018.11.021DOI Listing
February 2019

Simplifying the digital workflow of facial prostheses manufacturing using a three-dimensional (3D) database: setup, development, and aspects of virtual data validation for reproduction.

J Prosthodont Res 2019 Feb 18. Epub 2019 Feb 18.

Section "Medical Materials Science and Technology", Tuebingen University Hospital, Tuebingen, Germany.

Purpose: To set up the digital database (DDB) of various anatomical parts, skin details and retention elements in order to simplify the digital workflow of facial prostheses manufacturing; and to quantify the reproduction of skin wrinkles on the prostheses prototypes with stereolithography (SLA) and direct light processing (DLP) methods.

Methods: Two structured light scanners were used to obtain the nasal and auricle forms of 50 probands. Furthermore, the ala nasi and scapha areas were captured with the digital single lens reflex camera and saved in jpeg format. Read More

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http://dx.doi.org/10.1016/j.jpor.2019.01.004DOI Listing
February 2019

Calculation of flexor pollicis longus moment arm for wrist motion in a cadaver model validates the tenodesis effect for therapy.

J Hand Ther 2019 Feb 18. Epub 2019 Feb 18.

Tendon and Soft Tissue Biology Laboratory, Mayo Clinic, Rochester, MN, USA. Electronic address:

Introduction: Synergies of fingers and wrist motion have been incorporated into therapies for finger flexor tendon injuries to improve repair outcomes. Similar synergistic therapy strategies have not been well documented for the thumb.

Purpose Of The Study: The purpose of this study was to investigate the extent to which wrist motion enables a synergistic effect at the thumb in a cadaveric model by measuring flexor pollicis longus excursion and calculating the moment arm of this tendon at the wrist joint. Read More

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http://dx.doi.org/10.1016/j.jht.2019.01.005DOI Listing
February 2019

Cocaine use is associated with worse outcomes in patients treated with thoracic endovascular repair for type B aortic dissection.

J Vasc Surg 2019 Feb 18. Epub 2019 Feb 18.

Sanger Heart & Vascular Institute, Atrium Health, Charlotte, NC. Electronic address:

Objective: To describe and compare the clinical and anatomical characteristics and outcomes of patients with and without known cocaine use who underwent thoracic endovascular repair for type B aortic dissections.

Methods: Between January 2012 and January 2017, 186 patients underwent thoracic endovascular repair for type B aortic dissection at our institution. Clinical data and anatomical characteristics were collected under an institutional review board-approved protocol. Read More

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http://dx.doi.org/10.1016/j.jvs.2018.10.061DOI Listing
February 2019

Reuterinos as adjuvant for peri-implant treatment: A pilot study.

Int J Immunopathol Pharmacol 2019 Jan-Dec;33:2058738419827745

5 Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.

The objective of this study was to evaluate the effects of lozenges-containing Lactobacillus reuteri as an adjuvant treatment of peri-implant mucositis and to detect the level of L. reuteri colonization in the peri-implant tissues of treated patients. A total of 10 patients were selected. Read More

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http://dx.doi.org/10.1177/2058738419827745DOI Listing
February 2019

An annotated checklist of the macrodasyidan Gastrotricha from India.

Zootaxa 2019 Jan 21;4545(4):495-510. Epub 2019 Jan 21.

Crescent International School, Bario, Govindpur, Dhanbad 828109, Jharkhand, India..

We present a checklist of the macrodasyidan Gastrotricha fauna of India derived from original articles and comprehensive monographies regarding the Indian Fauna. Taxa and specimens described from India are discussed with special attention to their status, especially those species previously known from distant geographic areas. A total of 43 species have been recorded from 4 States and 2 Union territories. Read More

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http://dx.doi.org/10.11646/zootaxa.4545.4.3DOI Listing
January 2019

Anatomical review of the ventral capsule/ventral striatum and the nucleus accumbens to guide target selection for deep brain stimulation for obsessive-compulsive disorder.

World Neurosurg 2019 Feb 18. Epub 2019 Feb 18.

Department of Neurosurgery, West Virginia University Hospital, Morgantown, USA.

Background: Disturbances in the brain's reward network underlie addiction, depression, and obsessive-compulsive disorder (OCD). The ventral capsule/ventral striatum (VC/VS) and nucleus accumbens (NAc) region is a clinically approved target for deep brain stimulation (DBS) for OCD and investigational for other applications.

Methods: We performed a comprehensive literature review to define the clinically relevant anatomy and connectivity of the VC/VS and NAc region to guide target selection for DBS. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.254DOI Listing
February 2019

The super-learning hypothesis: integrating learning processes across cortex, cerebellum and basal ganglia.

Neurosci Biobehav Rev 2019 Feb 18. Epub 2019 Feb 18.

Institute of Cognitive Sciences and Technologies, National Research Council, Via San Martino della Battaglia 44, 00185 Rome, Italy.

Despite wide evidence suggesting anatomical and functional interactions between cortex, cerebellum and basal ganglia, the learning processes operating within them --often viewed as respectively unsupervised, supervised and reinforcement learning-- are studied in isolation, neglecting their strong interdependence. We discuss how those brain areas form a highly integrated system combining different learning mechanisms into an effective super-learning process supporting the acquisition of flexible motor behaviour. The term "super-learning" does not indicate a new learning paradigm. Read More

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http://dx.doi.org/10.1016/j.neubiorev.2019.02.008DOI Listing
February 2019

EyeSAM: graph-based localization and mapping of retinal vasculature during intraocular microsurgery.

Int J Comput Assist Radiol Surg 2019 Feb 21. Epub 2019 Feb 21.

The Robotics Institute, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.

Purpose: Robot-assisted intraocular microsurgery can improve performance by aiding the surgeon in operating on delicate micron-scale anatomical structures of the eye. In order to account for the eyeball motion that is typical in intraocular surgery, there is a need for fast and accurate algorithms that map the retinal vasculature and localize the retina with respect to the microscope.

Methods: This work extends our previous work by a graph-based SLAM formulation using a sparse incremental smoothing and mapping (iSAM) algorithm. Read More

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http://dx.doi.org/10.1007/s11548-019-01925-1DOI Listing
February 2019

The Adaptive Hermite Fractal Tree (AHFT): a novel surgical 3D path planning approach with curvature and heading constraints.

Int J Comput Assist Radiol Surg 2019 Feb 21. Epub 2019 Feb 21.

Mechatronics in Medicine Laboratory, Department of Mechanical Engineering, Imperial College, London, UK.

Purpose: In the context of minimally invasive neurosurgery, steerable needles such as the one developed within the Horizon2020-funded EDEN2020 project (Frasson et al. in Proc Inst Mech Eng Part H J Eng Med 224(6):775-88, 2010. https://doi. Read More

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http://dx.doi.org/10.1007/s11548-019-01923-3DOI Listing
February 2019

Association of Low Birth Weight With Altered Corneal Geometry and Axial Length in Adulthood in the German Gutenberg Health Study.

JAMA Ophthalmol 2019 Feb 21. Epub 2019 Feb 21.

Department of Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.

Importance: Low birth weight is associated with altered ocular organ development in childhood, including the morphology of the eye. However, no population-based data exist about this association in adulthood.

Objective: To evaluate whether low birth weight has a long-term association with anterior segment anatomy and axial length in adulthood. Read More

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http://dx.doi.org/10.1001/jamaophthalmol.2018.7121DOI Listing
February 2019

Variability of repairable bicuspid aortic valve phenotypes: towards an anatomical and repair-oriented classification.

Eur J Cardiothorac Surg 2019 Feb 20. Epub 2019 Feb 20.

Department of Cardiothoracic Surgery, Saarland University Medical Center, Homburg/Saar, Germany.

Objectives:: The bicuspid aortic valve (BAV) exists in a wide variety of valve phenotypes. The aim of this study was to assess the anatomical characteristics of the different phenotypes and develop a classification system to aid surgical repair.

Methods:: In 178 consecutive patients operated on for aortic insufficiency or aortic dilatation in 2 centres, 11 anatomical parameters of BAV were measured by echocardiography and intraoperatively. Read More

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http://dx.doi.org/10.1093/ejcts/ezz033DOI Listing
February 2019

Is it time for international guidelines on physical restraint in psychiatric patients?

Clin Ter 2019 Jan-Feb;170(1):e68-e70

Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome - IRCCS Neuromed.

The freedom-restraining measures used during Involuntary Health Treatment (IHT) are highly criticized in the medical community. Physical restraint techniques are currently largely used worldwide in Psychiatry. The use of restraints against the patient's will can be considered a serious intrusion of basic human rights and even an act of violence against the patient. Read More

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http://dx.doi.org/10.7417/CT.2019.2110DOI Listing
February 2019

Should all lobular breast carcinoma undergo staging gastrointestinal endoscopy?

Breast J 2019 Feb 20. Epub 2019 Feb 20.

Department of Surgery, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.1111/tbj.13229DOI Listing
February 2019

Subject-specific modelling of pneumoperitoneum: model implementation, validation and human feasibility assessment.

Int J Comput Assist Radiol Surg 2019 Feb 20. Epub 2019 Feb 20.

Department of Surgery and Cancer, Imperial College London, London, UK.

Purpose: The aim of this study is to propose a model that simulates patient-specific anatomical changes resulting from pneumoperitoneum, using preoperative data as input. The framework can assist the surgeon through a real-time visualisation and interaction with the model. Such could further facilitate surgical planning preoperatively, by defining a surgical strategy, and intraoperatively to estimate port positions. Read More

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http://dx.doi.org/10.1007/s11548-019-01924-2DOI Listing
February 2019

Multi-modal image analysis for semi-automatic segmentation of the total liver and liver arterial perfusion territories for radioembolization.

EJNMMI Res 2019 Feb 20;9(1):19. Epub 2019 Feb 20.

Nuclear Medicine, Department of imaging and pathology, UZ & KU Leuven, Leuven, Belgium.

Purpose: We have developed a multi-modal imaging approach for SIRT, combining Tc-MAA SPECT/CT and/or Y PET, F-FDG PET/CT, and contrast-enhanced CBCT for voxel-based dosimetry, as a tool for treatment planning and verification. For radiation dose prediction calculations, a segmentation of the total liver volume and of the liver perfusion territories is required.

Method: In this paper, we proposed a procedure for multi-modal image analysis to assist SIRT treatment planning. Read More

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http://dx.doi.org/10.1186/s13550-019-0485-xDOI Listing
February 2019

Comparison of different surgical techniques for pelvic floor repair in elderly women: a multi-institutional study.

Arch Gynecol Obstet 2019 Feb 20. Epub 2019 Feb 20.

Department of General Surgery and Gynecology, Diaconesses-Croix Saint Simon Hospital Paris, Paris, France.

Purpose: The prevalence of pelvic organ prolapse (POP) is increasing. The number of women aged 70-80 years requiring surgical management for POP is also increasing. The purpose of this study was to compare the complications associated with three pelvic organ prolapse repair methods, sacrocolpopexy (SCP), native tissue repair (NTR), and vaginal mesh repair (VMR), in women aged 70-80 years. Read More

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http://dx.doi.org/10.1007/s00404-019-05076-1DOI Listing
February 2019

Repair Techniques for Failed Double-Eyelids Involving Restoration of Eyelid Anatomical Structure and Function.

Aesthetic Plast Surg 2019 Feb 20. Epub 2019 Feb 20.

Mylike Medical Cosmetic Hospital, Shanghai, China.

Background: This study aimed to evaluate techniques for repairing previously failed double-eyelid surgeries based on different anatomical structure injuries.

Methods: A total of 120 patients with failed double-eyelids in our hospital were enrolled and classified into four types according to their anatomical structure damage: type I, unsmooth radians of the double-eyelid line; type II, upper socket depression; type III, iatrogenic ptosis; and type IV, comprehensive damage. Accordingly, methods of restoration included orbital septum fat supplement, repair of levator palpebrae superioris, and treatment of scar. Read More

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http://dx.doi.org/10.1007/s00266-019-01328-2DOI Listing
February 2019

Improved growth performance due to hypertrophied intestinal absorptive epithelial cells by heat killed Lactobacillus sakei HS-1 in broiler chickens.

J Anim Sci 2019 Feb 20. Epub 2019 Feb 20.

Shimotakaoka, Miki-cho, Kagawa-ken, Japan.

This study investigated the effect of heat-killed Lactobacillus sakei HS-1 (HK LS HS-1) on the growth performance and intestinal histology of broilers through two feeding trials. In trial 1, 48 male broilers were separated into three groups: 1) basal diet (1-21 d, including antibiotics; 21-49 d, not including antibiotics) supplemented with 0 bacterial cells of HK LS HS-1/g (control); 2) 106 bacterial cells were used; and 3) 108 bacterial cells were used. Trial 2 was carried out in a tropical area of Thailand, where fifty-7-d old male broilers were separated into 2 groups: 1) basal diet (control group); and 2) basal diet supplemented with 107 bacterial cells of HK LS HS-1/g. Read More

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http://dx.doi.org/10.1093/jas/skz075DOI Listing
February 2019

Epidemiological Survey of Human Dermatophytosis due to Zoophilic Species in Tehran, Iran.

Iran J Public Health 2018 Dec;47(12):1930-1936

School of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran.

Background: Dermatophytosis is known as one of the most frequent cutaneous infections that lead to public health problems to human and animals. The purpose of this study was to determine the prevalence of human dermatophytosis due to zoophilic species in Tehran, Iran from 2014 to 2015.

Methods: Overall, 3989 patients with clinically suspected fungal infections were studied. Read More

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December 2018

Highly efficient novel recombinant L-asparaginase with no glutaminase activity from a new halo-thermotolerant strain.

Bioimpacts 2019 13;9(1):15-23. Epub 2018 Sep 13.

Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

The bacterial enzyme has gained more attention in therapeutic application because of the higher substrate specificity and longer half-life. L-asparaginase is an important enzyme with known antineoplastic effect against acute lymphoblastic leukemia (ALL). Novel L-asparaginase genes were identified from a locally isolated halo-thermotolerant strain and the recombinant enzymes were overexpressed in modified strains, Origami B and BL21. Read More

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http://dx.doi.org/10.15171/bi.2019.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378094PMC
September 2018

3D multi-tissue printing for kidney transplantation.

Quant Imaging Med Surg 2019 Jan;9(1):101-106

Department of Musculoskeletal Imaging, CHRU Besancon, 25000 Besancon, France.

The kidneys are among the most commonly transplanted organs in the world. Transplant patients, as a consequence of their kidney disease and other risk factors which make it difficult for the surgeon to perform vascular anastomosis during kidney transplantation, often have numerous arterial calcifications. The preoperative assessment for transplantation includes an abdominal and pelvic CT scan without contrast that allows for the mapping of atheromatous calcification. Read More

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http://dx.doi.org/10.21037/qims.2018.10.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351812PMC
January 2019

Patient-specific 3D printed model of biliary ducts with congenital cyst.

Quant Imaging Med Surg 2019 Jan;9(1):86-93

Discipline of Medical Radiation Sciences, School of Molecular and Life Sciences, Curtin University, Perth, Western Australia, Australia.

Background: 3D printing has shown great promise in medical applications, with increasing reports in liver diseases. However, research on 3D printing in biliary disease is limited with lack of studies on validation of model accuracy. In this study, we presented our experience of creating a realistic 3D printed model of biliary ducts with congenital cyst. Read More

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http://dx.doi.org/10.21037/qims.2018.12.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351815PMC
January 2019

Optimization of computed tomography pulmonary angiography protocols using 3D printed model with simulation of pulmonary embolism.

Quant Imaging Med Surg 2019 Jan;9(1):53-62

Discipline of Medical Radiation Sciences, School of Molecular and Life Sciences, Curtin University, Perth, Western Australia, Australia.

Background: Three-dimensional (3D) printing has been shown to accurately replicate anatomical structures and pathologies in complex cardiovascular disease. Application of 3D printed models to simulate pulmonary arteries and pulmonary embolism (PE) could assist development of computed tomography pulmonary angiography (CTPA) protocols with low radiation dose, however, this has not been studied in the literature. The aim of this study was to investigate optimal CTPA protocols for detection of PE based on a 3D printed pulmonary model. Read More

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http://dx.doi.org/10.21037/qims.2018.09.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351811PMC
January 2019