Anal Quant Cytol Histol 2011 Oct;33(5):271-6
Department of Oral Pathology, School of Dentistry, Universidade Federal do Rio Grande do Sul, RS, Brazil.
Objective: To assess cytogenetic abnormalities through quantification of micronuclei, broken eggs, and karyorrhexis, in cells from normal oral mucosa of individuals exposed to carcinogens (alcohol and tobacco) and adjacent to leukoplakias and squamous cell carcinomas.
Study Design: The sample was composed of 40 subjects aged > 30 years, divided into four groups: control, alcohol/tobacco, leukoplakia, and squamous cell carcinoma. For control and alcohol/tobacco groups, cells were collected from lower lip, tongue border, and floor of the mouth. Read More