Readily prepared iminocoumarin for rapid, colorimetric and ratiometric fluorescent detection of phosgene.
Anal Chim Acta 2018 Oct 21;1029:97-103. Epub 2018 Apr 21.
Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, 430079, PR China. Electronic address:
In this paper, a new colorimetric and ratiometric fluorescent probe for the rapid detection of phosgene is reported. This probe is based on a readily prepared and highly fluorescent iminocoumarin, which reacts rapidly with phosgene to form a cyclic carbamate product to produce, distinctive colorimetric and ratiometric fluorescent signal changes. The detection of phosgene with this probe is fast (complete within 2 min), highly selective and sensitive with a detection limit of 27 nM in solution. Read More