1,896 results match your criteria Anales de la Real Academia Nacional de Medicina[Journal]


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An R Acad Nac Med (Madr) 2014 ;131(2):705-12

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September 2016
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An R Acad Nac Med (Madr) 2014 ;131(2):699-701

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September 2016

[MEDICINE: THE MAIN ENGINE OF THE GENERATION OF 1914].

An R Acad Nac Med (Madr) 2014 ;131(2):687-99

This text shows how the so-called generation of 1914 was mostly made of people from the scientific world, in the broadest sense of the term--from Physics and other experimental sciences to Biology, Medicine, the Humanities, Law and the Social Sciences. In the first third of the 20th century, this generation radically transformed the panorama of scientific research in Spain. In this process, physicians played an essential role. Read More

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September 2016

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An R Acad Nac Med (Madr) 2014 ;131(2):684-6

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September 2016

[JULIAN CALLEJA AND CARLOS MARÍA CORTEZO. TWO KEY FIGURES IN THE CENTENNIAL BUILDING THE ROYAL ACADEMY OF MEDICINE].

An R Acad Nac Med (Madr) 2014 ;131(2):671-84

In this year of 2014 we celebrate the centenary of the current building RANM, and remember the life and work of two of the leading figures, not only from the Academy but also the Spanish politics of the time: the doctors Julian Calleja and Carlos María Cortezo, whose work was essential for the building was erected as a permanent seat. Read More

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September 2016

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Authors:
Joseph J Fins

An R Acad Nac Med (Madr) 2014 ;131(2):639-67

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September 2016
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An R Acad Nac Med (Madr) 2014 ;131(2):633-8

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September 2016
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An R Acad Nac Med (Madr) 2014 ;131(2):627-9

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September 2016

[TERTIARY PERITONITIS].

An R Acad Nac Med (Madr) 2014 ;131(2):597-627

Tertiary peritonitis is an intraabdominal infection that arises in some patients with secondary peritonitis, despite receiving appropriate treatment. Recently described, it is a syndrome of late peritonitis and we are still lacking a precise and widely adopted definition. Diagnosis is difficult and treatment is complex. Read More

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September 2016
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An R Acad Nac Med (Madr) 2014 ;131(2):594-6

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September 2016

[PRENATAL DIAGNOSIS: EVOLUTION OF CLINICAL INDICATIONS AND THE SOCIETY IN THE PAST 30 YEARS].

An R Acad Nac Med (Madr) 2014 ;131(2):563-94

Here we report the results of prenatal diagnosis at the Hospital Universitario Ramón y Cajal since its opening in 1979 to 2010, establishing a parallelism between the different methodologies for screening and prenatal diagnosis, clinical indications, and demographic changes. It shows how the indications have varied as to the structure of the population did. These changes have been possible thanks to the fact that the screening and prenatal diagnosis methods have allowed it. Read More

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September 2016
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[LIMITATION OF THE THERAPEUTIC EFFORT: A CLINICAL PERSPECTIVE].

An R Acad Nac Med (Madr) 2014 ;131(2):551-61; discussion 561-2

There is a clear trend in the past years, dies in the environment of the patient's home. The seemingly paradoxical fact that the intensive care units are produced at the same time use them more and more, in an attempt by patients and relatives run down facilities that offer the most advanced technologies. In many cases the UCI can be considered as a therapeutic trial, which occasionally fails. Read More

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September 2016

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An R Acad Nac Med (Madr) 2014 ;131(2):547-50

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September 2016

[ETHICS OF THE LIMITATION OF LIFE-SUSTAINING TREATMENTS].

An R Acad Nac Med (Madr) 2014 ;131(2):513-47

The development over the last half century of the Life Support Technologies and the advent of the Intensive Care Units, have raised a wide range of new problems for ethical reflection. It is not by chance that the birth of Bioethics coincided with the birth of the Intensive Care Units. The first and most important of these problems is the withholding or withdrawing of the life support measures. Read More

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September 2016
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An R Acad Nac Med (Madr) 2014 ;131(2):508-10

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September 2016

[AGING, HEALTH AND SOCIETY: CHALLENGES FOR NEXT DECADE].

An R Acad Nac Med (Madr) 2014 ;131(2):497-508

Main challenges that may appear in our country along next decade related with the aging process are discussed. First of these challenges must take into account demography changes. Absolute number and. Read More

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September 2016

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An R Acad Nac Med (Madr) 2014 ;131(2):492-6

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September 2016

[IRRITABLE BOWEL SYNDROME. NEW HORIZONS].

An R Acad Nac Med (Madr) 2014 ;131(2):479-92

Irritable bowel syndrome is a chronic disorder of complex genesis. Infections, indiscriminate use of antibiotics and bowel cleansing may affect the composition of the microbiota. Knowledge of host-microbiota interaction is important to deepen their pathogenesis and allow therapeutic modulation of the microbiota. Read More

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September 2016
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An R Acad Nac Med (Madr) 2014 ;131(2):469-76

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September 2016
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An R Acad Nac Med (Madr) 2014 ;131(2):461-9

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September 2016

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An R Acad Nac Med (Madr) 2014 ;131(2):457-8

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September 2016

[SYNERGISTIC ACTIVITY OF DEGUELIN AND FLUDARABINE IN PRIMARY CELLS FROM CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS (CLL) AND IN A CLL MURINE MODEL].

An R Acad Nac Med (Madr) 2014 ;131(2):441-56

Chronic lymphocytic leukemia (CLL), a malignancy of mature B cells, remains incurable with chemotherapy. Our aim was to test if deguelin, a natural rotenoid which inhibits PI3K/AKT, could enhance the sensitivity to fludarabine of CLL cells and explore the therapeutic potential of deguelin/fludarabine combination in the inbreed New Zealand Black (NZB) mouse model of CLL. Our results indicate that deguelin induced apoptosis in cells from CLL patients in culture and showed a moderate synergy with fludarabine in cytoprotective culture conditions. Read More

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September 2016

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An R Acad Nac Med (Madr) 2014 ;131(2):437-9

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September 2016

[DISEASES AND ITS TYPES].

An R Acad Nac Med (Madr) 2014 ;131(2):421-37

With this conference, I intend to define what is the disease and its types explaining the criteria for classification according to different points of view, as the etiologic, teleological, social impact, spatial and temporal distribution, production mechanisms, risk factors, which affects organs, etc. As there are diseases that do not exist dedicate a final chapter of this dissertation to develop them. Read More

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September 2016
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An R Acad Nac Med (Madr) 2014 ;131(2):416-8

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September 2016

[OPERATION TO SUBSTITUTE THE LUMBAR URETER. LOWERING OF THE RENAL VEINS].

An R Acad Nac Med (Madr) 2014 ;131(2):399-416

A new operation to lower the aortic anastomosis of the renal artery is de- scribed. This procedure allows the left Kidney to be lowered enough to enable repair after resections of the upper urinary tract. Renal hemodynamics were not altered and good results were obtained with no complications. Read More

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September 2016
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An R Acad Nac Med (Madr) 2014 ;131(2):393-8

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September 2016
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[AORTIC ANEURYSMS. THE SILENT ENEMIES].

An R Acad Nac Med (Madr) 2014 ;131(2):381-93

Aortic aneurysms are caused by a localized degeneration of the middle layer, which promotes the formation and progressive expansion of the aneurysm. In ascending thoracic aorta, usually have genetic cause, and intervene when they reach 5 to 5.5 cm in diameter. Read More

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September 2016

[NEUROSPIRITUALITY].

An R Acad Nac Med (Madr) 2014 ;131(1):307-26; discussion 327-31

Neurospirituality refers to the fact that the brain is able to produce spiritual experiences. The hypothesis put forward here is that the origin of spiritual experiences lies in the hyperactivity of limbic structures within the depth of the temporal lobe. The characteristics of these phenomena are the common denominator of the mystic experiences, the near to death experiences, the symptoms of the temporal lobe epilepsy and those following the consumption of entheogen drugs. Read More

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September 2016

[OROPHARYS CANCER: THE SQUAMOUS CELL].

An R Acad Nac Med (Madr) 2014 ;131(1):289-302; discussion 302-5

The Diffuse Large B-Cell Lymphoma is the most frequent non Hodgkin Lymphoma. The role of CT/PET in this relatively homogeneous group of lymphomas is controversial. It rarely changes the management of the patients in the initial staging. Read More

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September 2016
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[MEDICOLEGAL ASSESSMENT OF THE AGGRESSOR TO PREVENT ADVERSE OUTCOMES IN WOMEN VIOLENCE].

An R Acad Nac Med (Madr) 2014 ;131(1):273-86; discussion 286-8

Violence against women is a health care problem because it is very prevalent and its consequences are serious. The number of deaths due to this problem keep being alarming. Measures to prevent this could be:--Make victims and their families know that complaint is very important. Read More

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September 2016

[THE FRENCH ANATOMICAL XAVIER BICHAT (1771 - 1802). FUNDATOR OF DOCTRINE OF TISSUES. BIOGRAPHICAL MEMORY BEFORE HIS GRAVE].

An R Acad Nac Med (Madr) 2014 ;131(1):257-71; discussion 272

It is reminded to Marie Francois Xavier Bichat (1771-1802), French physician who figure in the pages of the history of the Universal Medicine. With him begins the anatomic mentality in the nineteenth century, which in 1801 introduced the concept of tissue in his book "Anatomie Generale". With unprecedented nature is disclosed his tomb in Paris' Pere Lachaise cemetery visited by the author, fact that motivated before it about his memories and historical work, which appears in the communication, as a tribute to his memory. Read More

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September 2016
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[MEDICINE IN THE LITERARY WORK OF MIGUEL TORCA].

An R Acad Nac Med (Madr) 2014 ;131(1):239-54; discussion 255-6

Miguel Torga (Sao Martinho de Anta 1907 - Coimbra 1995) was one of the most important portuguese writers of the twentieth century. There is such identity between his medical and literary activity that he used to say that "his own hand not only writes but also prescribes". Reading his work, mainly autobiographical, allows us to analyze their vision of medicine, the patient physician relationship and how a doctor lives his own disease. Read More

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September 2016

[CONGENITAL ADRENAL HYPERPASIA].

An R Acad Nac Med (Madr) 2014 ;131(1):221-34; discussion 234-6

It is presented the clinical and physiopathological characteristics of most relevant CAH during pediatric ages. Also it is discussed the dauting benefit derived from analysing in all newborns 17-OH-progesterone in a few blood drops-embedded filter-paper. In addition it is emphasized the interest of treating risk pregnancies before delivery. Read More

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September 2016

[RADIATION ONCOLOGY: CONTEXT IN CANCER MEDICINE AND CLINICAL TRASLATIONAL RESEARCH MODELS].

An R Acad Nac Med (Madr) 2014 ;131(1):189-217; discussion 218-20

Radiation Oncology is a clinical speciality supported by technological development including biomedical imaging, ionizing radiation generators and radiobiology of cancer and normal tissues. Translational research and development opportunities incorporate clinical models available in hospital practice with academic interest in health care innovative approaches. Examples of mature research projects in translational radiation oncology are described: a) molecular imaging and expression for radioresponse assessment; b) oligorecurrent cancer results after rescue surgery and intensified radiotherapy; c) stereotactic surgical navigation for intraoperative radiotherapy. Read More

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September 2016

[FROM THE CT-PET TO THE MRI-PET].

An R Acad Nac Med (Madr) 2014 ;131(1):179-84; discussion 184-8

CT-PET is a multimodality imaging technique which diagnostic utility has been demostrated especially in oncology and neurosciences. There is about 100 equipments of this modality in Spain. MRI-PET ia a new multimodality imaging technique recently installed in Spain. Read More

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September 2016

[THE THALAMIC DOPAMINERGIC SYSTEM. A NOVEL SYSTEM IN THE PRIMATE BRAIN].

An R Acad Nac Med (Madr) 2014 ;131(1):151-72; discussion 172-5

The human and macaque monkey thalamus receives an abundant dopamine innervation, as revealed by immunolabeling of axons for molecules specific for the dopaminergic phenotype. The distribution of the innervation is highly heterogeneous, with specific association, limbic and motor nuclei receiving the densest innervation. The origin of thalamic dopamine is multiple; it includes dopaminergic nuclei in the hypothalamus, periaqueductal gray, ventral mesencephalon and lateral parabrachial nucleus. Read More

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September 2016

[ANTIAGING TREATMENTS: WHAT ARE WE TALKING ABOUT?].

An R Acad Nac Med (Madr) 2014 ;131(1):127-50

Antiaging medicine is nowadays an equivocal topic frequently used in geriatric medicine. It is, also, one of the most important sources of medical costs. With the words "antiaging medicine" we may express several different desires: a) to arrive at advanced age in the best possible physical and mental conditions, b) to act in order to slowing the aging process associated changes, c) to revert some of these negative changes. Read More

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September 2016
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[PASSIVE TACTILE STIMULATION AS A WAY OF SPATIAL RECOGNITION IN SUBJECTS WITH SEVERE VISUAL IMPAIRMENT OR BLINDNESS].

An R Acad Nac Med (Madr) 2014 ;131(1):113-22; discussion 122-4

Regular tactile passive stimulation increases the lasting activation of a greater number of synaptic connections (neuroplasticity) in posterior cortical areas in subjects with blidness with duration and permanence of the neuroplasticity process. Assuming that the lack of stimulation logically involves a deficit due to the cerebral hypofunctionality; in the case of blind subjects such deficit should be more pronounced in the occipital lobe responsible of human vision. We found, after long period of táctile stimulation, that the occipital lobe was activated while having at the same time a visual "qualia" subjective sensation using transcranial magnetic stimulation occipital lobe inhibition decreases visual response. Read More

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September 2016

[THE MICROSCOPIC ALGAE AS HUMAN PATHOGENS].

An R Acad Nac Med (Madr) 2014 ;131(1):99-110; discussion 110-1

Some microscopic algae can cause different infectious diseases in humans, including skin, bone, and disseminated. These little-known emerging disease are more severe in immunocompromised patients. The confirmatory microbiological diagnosis must be done differential with yeast-like fungi that can be confused. Read More

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September 2016
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[THE GLOBAL AND ECONOMIC CRISIS. AND HEALTH MANAGEMENT].

An R Acad Nac Med (Madr) 2014 ;131(1):77-94; discussion 94-7

The Global and economic crisis and Health Management The Health care process discussed are 4 steps: assessment, planing, intervention and evaluation. The identify association between social factors linked to social vulnerability (socio economic status, unemployed, poverty) and objective health relate quality of life. The poverty rate is 24. Read More

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September 2016
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[LIGHT AND SHADOWS OF PSYCHIATRIC NOSOLOGY].

An R Acad Nac Med (Madr) 2014 ;131(1):57-73; discussion 73-4

Psychiatry is going through a deep crisis, both as a scientific discipline as a medical specialty. In the present paper we consider in length what we consider to be the two aspects that could explain the situation: the recurring disappointment with classification systems and the persistence of a localizacionism inadequate to explain normal and pathological behavior. Psychiatry lacks a definition of mental disorder that covers all situations, there are difficulties in drawing a precise distinction between normality and psychopathology, and the majority of these "diagnostic" categories are not validated by biological criteria. Read More

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September 2016
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[BODY AND CORPORALITY IN THE HUMAN BEING: SOME INTERDISCIPLINARY REFLECTIONS].

An R Acad Nac Med (Madr) 2014 ;131(1):41-54; discussion 54-5

The major purpose of this contribution is to illustrate some differential aspects between the human and the animal bodies, in order to understand the main distinctive characteristic of the human being: his or her rationality. Thus, we firstly deal with some considerations about the general anthropological framework in which the human body is going to be analysed. Next, we briefly explain the importance of the body for an adequate understanding of the intimacy and the biographical perspectives of the person. Read More

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September 2016
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[DESCRIPTION OF A RETROPERITONEAL ACCESS ROUTE TO THE VESSELS OF THE SPLEEN FOR SPLENORENAL ARTERIAL AND VENOUS ANASTOMOSIS].

An R Acad Nac Med (Madr) 2014 ;131(1):27-38; discussion 38-40

To perform arterial or venous spleno-renal anastomoses, surgeons have so far systematically used the transperitoneal way whic is burdened by a high mortality an morbility percentage. On the basis of anatomo-surgical considerations, a retroperitoneal approach has been found reaching the hilus of the spleen via the lumbar region; the first arterial spleno-renal anastomosis by this way was performed in 1972 and the first venous spleno-renal anastomosis due to portal hipertension also by this way was performed in 1974, the alter proving to be the least aggresive by avoiding damaging the páncreas, the most surgical and direct for reaching the splenic vessels thereby enabling a better exposure and an easier performing of the anastomoses. By being retroperitoneal, the loss or infección of the ascitic liquid in the cirrhotic patient is prevented. Read More

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September 2016

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An R Acad Nac Med (Madr) 2014 ;131(1):18-21

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September 2016

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An R Acad Nac Med (Madr) 2014 ;131(1):4-13

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September 2016

[Health system sustainability in the crisis context].

An R Acad Nac Med (Madr) 2012 ;129(2):701-13

BBVA.

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January 2014
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[Polycystic kidney disease: from genetics to dialysis].

An R Acad Nac Med (Madr) 2012 ;129(2):687-96; discussion 697-9

Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic cause of end stage renal disease. In addition, end-stage renal disease is complicated by acquired polycystic kidney disease. Recent advances in our understanding of the pathogenesis of ADPKD have identified the primary cilium as key to cystogenesis, and have defined the molecular, cellular and tissue pathogenesis of the disease, leading to the design of clinical trials that may ultimately lead to effective therapy of the disease. Read More

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January 2014

[Past, present and future of the neurosurgery].

An R Acad Nac Med (Madr) 2012 ;129(2):675-86

In this work a both historical and current journey for the main pathologies regarding the Neurosurgery is achieved, that is to say, the head injuries, the brain tumors, the cerebrovascular diseases, the pathology concerning the cerebrospinal fluid and malformations, the functional neurosurgery, the degenerative spine disease, the spine injuries, the spine tumors and eventually, the pathology of the Peripheral and Autonomic Nervous System. Also, references to what can be the Neurosurgery in a not very distant future are taken into account. Finally, some notes about investigation in the Neurosurgery field are added. Read More

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January 2014

[Reflections on current records of elite sport].

An R Acad Nac Med (Madr) 2012 ;129(2):643-74; discussion 74

Real Academia de Medicina del País Vasco.

The author presents the evolution of elite sport in its technical ways and records after the success of the Olympic Games in London (2012). He reflects on the limits of the human body in the records of speed, pole vault and high and long jumps. At the same time, he comments the situation of the current Spanish sport great success. Read More

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January 2014