Search Our Scientific Publications & Authors

An Pediatr (Barc) 2022 Jun 16. Epub 2022 Jun 16.

UCI Pediátrica. Hospital Universitario Central de Asturias, Oviedo, Asturias, España.

An Pediatr (Barc) 2022 Jun 16. Epub 2022 Jun 16.

Servicio de Pediatría, Hospital Universitario de Cabueñes, Gijón, España.

An Pediatr (Barc) 2022 Jun 17. Epub 2022 Jun 17.

Servicio de Pediatría. Hospital do Salnés. Vilagarcía de Arousa, Pontevedra, España.

An Pediatr (Engl Ed) 2022 Jun 22. Epub 2022 Jun 22.

Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Madrid, Spain. Electronic address:

An Pediatr (Engl Ed) 2022 Jun 18. Epub 2022 Jun 18.

Grupo de Investigación en Nutrición Pediátrica, Instituto de Investigación INCLIVA, Valencia, Spain. Electronic address:

Introduction: There are various scales designed to determine the risk of malnutrition at hospital admission in children. However, most of these instruments are developed and published in English. Their cross-cultural adaptation and validation being mandatory in order to be used in our country. Read More

An Pediatr (Engl Ed) 2022 Jun 18. Epub 2022 Jun 18.

Servicio de Pediatría, Hospital Universitario Cruces, Osakidetza, Barakaldo, Bizkaia, Spain; Biocruces Bizkaia Health Research Institute, Barakaldo, Bizkaia, Spain. Electronic address:

Introduction: Sickle cell disease is an emerging anemia in Europe leading to high morbidity with severe acute complications requiring hospital admission and chronic consequences. The management of these patients is complex and needs interdisciplinary care. The objective is to analyze clinical characteristics and management of patients with sickle cell disease admitted for acute complications. Read More

An Pediatr (Engl Ed) 2022 Jun 18. Epub 2022 Jun 18.

Neurología Neonatal, Fundación NeNe, Madrid, Spain.

Introduction: We do not have population data in Spain on the application of therapeutic hypothermia (TH). The objective was to examine adherence to management standards during TH of infants with hypoxic-ischemic encephalopathy (HIE).

Method: Multicenter observational cohort study from the beginning of TH (year 2010) in 5 hospitals in a Spanish region, until year 2019. Read More

An Pediatr (Engl Ed) 2022 Jun 18. Epub 2022 Jun 18.

Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

An Pediatr (Engl Ed) 2022 Jun 15. Epub 2022 Jun 15.

Centro de Atención Primaria "Ansoáin", Navarra, Spain.

Objectives: In Spain, the tools to diagnose COVID-19 were available in primary care from May 2020. Previously most studies described inpatients or patients in A&E departments, and fever and cough were the most frequent symptoms. This study aims to define the clinical picture of the pediatric COVID-19 in the community. Read More

An Pediatr (Engl Ed) 2022 Jun 10. Epub 2022 Jun 10.

Centro de Salud Zona Centro, Cáceres, Spain.

Background And Aims: To face the rapid spread of SARS-CoV2 coronavirus pandemic, home lockdown in Spain was decreed on 15th March 2020. The main objective of this study is to evaluate the impact of this constraint on glycemic control in children and adolescents with type 1 diabetes mellitus (T1D).

Patients And Methods: Observational, retrospective study in children and adolescents with T1D users of interstitial glucose monitoring systems. Read More

An Pediatr (Engl Ed) 2022 Jun 17. Epub 2022 Jun 17.

Servicio de Neonatología, Hospital Clínico Universitario de Santiago, Santiago de Compostela, A Coruña, Spain; Institudo de Investigaciones Sanitarias de Santiago (IDIS), Universidad de Santiago de Compostela, Santiago de Compostela, A Coruña, Spain. Electronic address:

The scant evidence on the use of transfusions in neonatal care explains the limitations of current clinical guidelines. Despite this, in this document we explore the most recent evidence to make recommendations for the clinical practice. The prevention of anaemia of prematurity, the use of protocols and restrictive transfusion strategies constitute the best approach for clinicians in this field. Read More

An Pediatr (Engl Ed) 2022 May 19;96(5):402-409. Epub 2021 Mar 19.

Departamento de Pediatría, Facultad de Medicina, Universidad de Menufia, Shibin el-Kom, Egypt.

Introduction: Stress ulcer prophylaxis (SUP) is commonly used in Paediatric Intensive Care Units (PICUs). However, strong evidence for this practice is lacking and there is a dire need for paediatric randomized controlled trials (RCTs). Our aim was to assess the usefulness of SUP with omeprazole in critically ill children. Read More

An Pediatr (Engl Ed) 2022 May 4;96(5):410-415. Epub 2022 Jun 4.

Hospital Universitario Materno Infantil Virgen de las Nieves, Granada, Spain; Instituto de Investigación Biosanitaria de Granada, Granada, Spain; Universidad de Granada, Granada, Spain. Electronic address:

Introduction: Natural killer (NK) cells play an important role in defense against tumor cells. The development and function of NK cells is governed by a dynamic balance between inhibition and activation of cell surface receptors, including KIR receptors.

Patients And Method: A case-control study is carried out that compares a group of 46 children diagnosed with malignant diseases, the control group is made up of 82 healthy children. Read More

An Pediatr (Engl Ed) 2022 06 2;96(6):544-547. Epub 2022 Jun 2.

Hospital Virgen de los Lirios, Alcoy, Alicante, Spain.

An Pediatr (Engl Ed) 2022 Jun 1;96(6):536.e1-536.e7. Epub 2022 Jun 1.

Departamento de Pediatría, Consorcio Hospital General, Universidad de Valencia, Spain; CIBER Fisiopatología Obesidad y Nutrición (CB06/03), Instituto de Salud Carlos III, Spain. Electronic address:

Arterial hypertension is the main modifiable risk factor for cardiovascular disease, occupying the first place among the causes of loss of life years adjusted for disability. In recent years, arterial hypertension in children and adolescents has gained ground in cardiovascular medicine thanks to progress made in several areas, fundamentally in pathophysiological and clinical research. Despite the advances that have been made in recent years, the prevention, diagnosis and treatment of high blood pressure in children and adolescents still have room for improvement. Read More

An Pediatr (Engl Ed) 2022 Jun 29;96(6):511-522. Epub 2022 May 29.

Department of Gastroenterology and Nutrition, University Childreńs Hospital Niño Jesús, Madrid, Spain.

Aim: Ketogenic dietary therapies (KDT) produce anticonvulsant and neuroprotective effects, reduce seizures and improve the cognitive state in patients with epilepsy. Our purpose was to evaluate the effects of KDT in children with refractory epilepsy (effectiveness, side effects, impact on nutritional status and growth).

Methods: A retrospective and prospective observational descriptive study was conducted in a Spanish tertiary hospital (January 2000 to December 2018). Read More

An Pediatr (Engl Ed) 2022 May 27;96(5):448.e1-448.e11. Epub 2022 May 27.

En representación de la Asociación Española de Pediatría de Atención Primaria, Grupo de trabajo Gastroenterología y Nutrición AEPAP; Unidad de Gastroenterología, Hepatología y Nutrición Pediátrica, Hospital Universitario Río Hortega, Valladolid, Spain.

Hypertransaminasemia is a frequent finding in pediatrics, which could reflect potentially treatable serious disease. The aim of this document is to establish, by reviewing the available evidence, a consensus for an adequate management of hypertransaminasemia, from its detection until the study is complete. To this end, a working group was formed with the participation of members of the Society of Pediatric Gastroenterology, Hepatology and Nutrition (SEGHNP), the Spanish Association of Primary Care Pediatrics (AEPap) and the Spanish Society of Primary Care Pediatrics (SEPEAP). Read More

An Pediatr (Engl Ed) 2022 Jun 26;96(6):476-484. Epub 2022 May 26.

Servicio de Pediatría, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

Introduction: In the treatment of patients with acute bronchiolitis there is great variability in clinical practice. Treatments whose efficacy has not been demonstrated are frequently used despite the recommendations contained in the Clinical Practice Guidelines.

Material And Methods: A quality improvement strategy is implemented in the care of patients with acute bronchiolitis in the Emergency Department, which is maintained for five years and is periodically updated to be increasingly restrictive regarding the use of bronchodilators. Read More

An Pediatr (Engl Ed) 2022 06 25;96(6):465-473. Epub 2022 May 25.

Editor asociado de Anales de Pediatría.

An Pediatr (Engl Ed) 2022 Jun 28;96(6):485-491. Epub 2022 May 28.

Complejo Asistencial de Zamora, Zamora, Spain.

Introduction: To estimate the impact of the incorporation of high-flow nasal cannule (HFNC) in patients admitted with acute bronchiolitis in a hospital without pediatric intensive care unit (PICU).

Material And Methods: Cohort study with historical control of bronchiolitis in a second-level hospital, before (2009-2012) and after (2015-2020) the implementation of HFNC. The main outcome was the need for admission to the PICU. Read More

An Pediatr (Engl Ed) 2022 06 11;96(6):537-539. Epub 2022 Mar 11.

Servicio de Urgencias Pediátricas, OSI Ezkerraldea-Enkarterri-Cruces, Barakaldo, Bizkaia, Spain. Electronic address:

An Pediatr (Engl Ed) 2022 Jun 28;96(6):492-500. Epub 2022 May 28.

Grupo de Investigación de Infección en el Paciente Pediátrico Inmunodeprimido, Vall d'Hebron Institut de Recerca (VHIR); Unidad de Patología Infecciosa e Inmunodeficiencias de Pediatría, Hospital Universitari Vall d'Hebron; Centro Jeffrey Modell para Diagnóstico e Investigación en Inmunodeficiencias Primarias, Barcelona, Catalonia, Spain. Electronic address:

Introduction: The aim of the study was to assess the incidence of hospital admission due to severe acute respiratory infection by respiratory syncytial virus (RSV-ARI) in children with primary immunodeficiencies (PIDs) and the severity of RSV-ARI in these patients.

Methods: We conducted a nationwide cross-sectional retrospective and prospective multicentre study in the 2011-2017 period. The study was performed in 15 Spanish hospitals and included children with PID who required hospital admission due to RSV-ARI. Read More

An Pediatr (Engl Ed) 2022 06 28;96(6):474-475. Epub 2022 May 28.

Presidente de la AEP.

An Pediatr (Engl Ed) 2022 Jun 24;96(6):523-535. Epub 2022 May 24.

Urgencias Pediátricas, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain.

Introduction: The efficacy and safety of the Rapid Intravenous Rehydration (RIR) guidelines in children affected by dehydration secondary to acute gastroenteritis is supported by current scientific evidence, but there is also great variability in its use in clinical practice.

Objective: To prepare a document with evidence-based recommendations about RIR in paediatric population.

Methods: The project was developed based on GRADE methodology, according to the following work schedule: Working Group training; creation of a catalogue of questions about research and definition of "relevant outcomes"; score and selection criteria for each item; bibliographic review; scientific evidence evaluation and synthesis (GRADE); review, discussion and creation of recommendations. Read More

An Pediatr (Barc) 2022 May 20. Epub 2022 May 20.

Unidad de Endocrinología y Diabetes Pediátrica, Servicio de Pediatría, Hospital Universitario Ramón y Cajal, Madrid, Spain.

An Pediatr (Engl Ed) 2022 04 6;96(4):365-367. Epub 2021 Mar 6.

Departamento de Cirugía Cardiaca Pediátrica, Hospital Universitario La Paz-Hospital Universitario Ramón y Cajal, Madrid, Spain.

An Pediatr (Engl Ed) 2022 Apr 19;96(4):334-341. Epub 2021 Mar 19.

Centro Nacional de Gripe de Valladolid, Edifico Rondilla, Hospital Clínico Universitario de Valladolid, Valladolid, Spain; Unidad de Virología, Servicio de Microbiología e Inmunología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain; Servicio de Microbiología, Hospital Universitario Río Hortega, Valladolid, Spain.

Introduction: Coinfections of influenza and other respiratory viruses (ORVs) are frequent in the epidemic season. The aim of this study was to examine the demographic and virological variables associated with coinfections by influenza and ORVs.

Materials And Methods: We analysed respiratory samples of patients with laboratory-confirmed influenza using molecular diagnostic methods obtained in 8 consecutive influenza seasons (2011-2012 to 2018-2019). Read More

An Pediatr (Engl Ed) 2022 May 20;96(5):394-401. Epub 2022 May 20.

Unidad de Atención Integral Paliativa Pediátrica, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

Introduction: Around 2000 children and adolescents die each year in Spain, however, we know little about the particularities of deaths in paediatrics. The purpose of this study is to document the characteristics of patients who die in the care of paediatric palliative care teams in Spain.

Patients And Methods: Retrospective, descriptive, multicentre study. Read More

An Pediatr (Engl Ed) 2022 May 17. Epub 2022 May 17.

Servicio de Pediatría, Hospital Universitario de Móstoles, Móstoles, Madrid, Spain.

An Pediatr (Engl Ed) 2022 May 13;96(5):431-440. Epub 2022 May 13.

Sección de Gastroenterología y Nutrición Infantil, Hospital Regional Universitario de, Málaga, Spain.

Introduction: Oropharyngeal dysphagia (DOF) without proper evaluation can be underdiagnosed in certain groups of the pediatricpopulation. Meeting the needs of these patients can lead to an overload of their caregivers.

Objectives: To describe the epidemiological and clinical characteristics of the patients evaluated after starting a monographic DOF clinic (C-DOF) and study whether there are changes at the nutritional level, as well as the burden and impact that caregivers find on quality of life related to health (HRQL). Read More