70 results match your criteria Anal Surgery Fissurectomy


[Chronic anal fissure: etiopathogenesis, diagnosis, treatment].

Khirurgiia (Mosk) 2018 (11):89-95

Municipal Clinical Hospital #24 of Moscow Healthcare Department, Moscow, Russia.

Etiology, epidemiology and pathophysiology of anal fissure are examined in the article in order to determine the most optimal treatment strategy. The authors concluded that the most effective treatment is combined approach using both minimally invasive surgery and various medicines for anal spasm reduction. Read More

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http://dx.doi.org/10.17116/hirurgia201811189DOI Listing
January 2018
1 Read

Long-term Outcome of a Fissurectomy: A Prospective Single-Arm Study of 50 Operations out of 349 Initial Patients.

Ann Coloproctol 2018 Apr 30;34(2):83-87. Epub 2018 Apr 30.

Proctologie Médico-Chirurgicale, Institut Léopold Bellan, Groupe Hospitalier Paris Saint-Joseph, Paris, France.

Purpose: The surgical standard of care for patients with chronic anal fissure is still disputed. We aimed to assess the natural course of idiopathic anal fissure and the long-term outcome of a fissurectomy as a surgical treatment.

Methods: All consecutive patients referred to a single expert practitioner in a tertiary centre were primarily included. Read More

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http://dx.doi.org/10.3393/ac.2017.06.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951090PMC
April 2018
2 Reads

Operative and medical treatment of chronic anal fissures-a review and network meta-analysis of randomized controlled trials.

J Gastroenterol 2017 Jun 10;52(6):663-676. Epub 2017 Apr 10.

Department of Surgery, Cantonal Hospital of St. Gallen, 9007, St. Gallen, Switzerland.

Anal fissures are a common problem and have a cumulative lifetime incidence of 11%. Previous reviews on anal fissures show inconsistent results regarding post-interventional healing and incontinence rates. In this review our aim was to compare the treatments for chronic anal fissures by incorporating indirect comparisons using network meta-analysis. Read More

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http://link.springer.com/10.1007/s00535-017-1335-0
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http://dx.doi.org/10.1007/s00535-017-1335-0DOI Listing
June 2017
12 Reads

Efficacy of Fissurectomy and Botox for Chronic Anal Fissure.

Authors:
Richard L Nelson

Dis Colon Rectum 2016 May;59(5):e41

Evanston, Illinois.

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http://dx.doi.org/10.1097/DCR.0000000000000563DOI Listing
May 2016
16 Reads

Fissurectomy Combined with High-Dose Botulinum Toxin Is a Safe and Effective Treatment for Chronic Anal Fissure and a Promising Alternative to Surgical Sphincterotomy.

Dis Colon Rectum 2015 Oct;58(10):967-73

Warrington Hospital, Warrington, Merseyside, United Kingdom.

Background: There is paucity of data on the long-term outcome of the combination of fissurectomy and botulinum toxin A injection for the management of chronic anal fissure.

Objectives: The aim of this study is to assess the safety, efficacy, and long-term outcome of the combination of fissurectomy and botulinum toxin A injection.

Design: This is a nonrandomized prospective cohort study. Read More

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http://dx.doi.org/10.1097/DCR.0000000000000434DOI Listing
October 2015
4 Reads

Prospective Single-Center Observational Study of Routine Histopathologic Evaluation of Macroscopically Normal Hemorrhoidectomy and Fissurectomy Specimens in Search of Anal Intraepithelial Neoplasia.

Dis Colon Rectum 2015 Jul;58(7):692-7

1 Service de Proctologie Médico-Interventionnelle, Groupe Hospitalier Diaconesses Croix-Saint-Simon, Paris, France 2 Service d'Anatomie et de Cytologie pathologiques, Hôpital Saint-Antoine, Paris, France.

Background: The necessity for routine histopathologic evaluation of hemorrhoidectomy specimens considered free of suspicious areas after careful visual and manual inspection remains controversial.

Objective: The purpose of this work was to prospectively study the prevalence of anal intraepithelial neoplasia in macroscopically normal operative specimens.

Design And Patients: From October 2005 to September 2010, all hemorrhoidectomy and fissurectomy specimens were sent for routine histopathologic analysis. Read More

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http://dx.doi.org/10.1097/DCR.0000000000000387DOI Listing
July 2015
3 Reads

[Management of complications of fissure and fistula surgery].

Authors:
Andreas Ommer

Chirurg 2015 Aug;86(8):734-40

Kompetenzzentrum für Koloproktologie, End- und Dickdarm-Zentrum Essen, Rüttenscheiderstr. 66, 45130, Essen, Deutschland,

Background: Fistula-in-ano and anal fissures are common proctological diseases. In most cases of anal fissures conservative treatment provides good clinical results, whereas for fistula-in-ano operative treatment is the only option.

Objective: The most important and for the patient most stressful long-term complication is postoperative incontinence, especially as the deliberate severance of the anal sphincter musculature is part of the treatment for many patients. Read More

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http://link.springer.com/10.1007/s00104-015-0001-4
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http://dx.doi.org/10.1007/s00104-015-0001-4DOI Listing
August 2015
6 Reads

Combined approach in the treatment of chronic anal fissures.

Updates Surg 2015 Mar 21;67(1):83-9. Epub 2015 Apr 21.

Department of Surgery, University Medical Centre Mannheim, Medical Faculty Mannheim of the University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany,

This study was designed to evaluate the healing and complications rates in surgically and conservatively treated patients with chronic anal fissure. Conservative treatment consisted of nitrate or diltiazem ointment. In case of surgery, fissurectomy was performed. Read More

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http://dx.doi.org/10.1007/s13304-015-0290-7DOI Listing

Dermal flap advancement combined with conservative sphincterotomy in the treatment of chronic anal fissure.

Am Surg 2015 Feb;81(2):133-42

Colorectal and Inflammatory Bowel Diseases Unit, First Department of Propaedeutic Surgery of Athens Medical School, Athens, Greece.

Lateral internal sphincterotomy (LIS) is considered the surgical treatment of choice for chronic anal fissure (CAF). Flap techniques for fissure coverage have the advantage of primary wound healing, potentially providing better functional results and faster pain relief. The standard surgical strategy for CAF consisting of conventional LIS (CLIS) up to the dentate line was modified by "tailoring" the LIS to the apex of the CAF, but never greater than 1 cm, and by advancing a dermal flap for coverage of the CAF (LIS + flap) after fissurectomy. Read More

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February 2015
21 Reads

Update on the management of anal fissure.

Authors:
T Higuero

J Visc Surg 2015 Apr 8;152(2 Suppl):S37-43. Epub 2014 Oct 8.

11, boulevard du Général-Leclerc, 06240 Beausoleil, France. Electronic address:

Anal fissure is an ulceration of the anoderm in the anal canal. Its pathogenesis is due to multiple factors: mechanical trauma, sphincter spasm, and ischemia. Treatment must address these causative factors. Read More

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http://dx.doi.org/10.1016/j.jviscsurg.2014.07.007DOI Listing
April 2015
22 Reads

Sphincter-Preserving Therapy for Treating a Chronic Anal Fissure: Long-term Outcomes.

Authors:
Ridzuan Farouk

Ann Coloproctol 2014 Jun 23;30(3):132-4. Epub 2014 Jun 23.

Department of Surgery, National University Hospital, Singapore.

Purpose: To estimate the risk of recurrent fissure in ano after sphincter preserving treatments.

Methods: A retrospective case note review, combined with a telephone survey was conducted for all patients treated for a chronic anal fissure between 1998 and 2008.

Results: Six hundred and twelve patients (303 women: mean age, 39 years; range, 16-86 years) were treated for chronic anal fissure between 1998 and 2008. Read More

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http://dx.doi.org/10.3393/ac.2014.30.3.132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079811PMC
June 2014
3 Reads

The efficacy and morbidity of different surgical treatment techniques for chronic anal fissure: an academic colorectal experience.

Am Surg 2014 Mar;80(3):241-4

Greenville Hospital System, University Medical Center, Greenville, South Carolina, USA.

Up to 40 per cent of chronic fissures will fail to heal with medical treatment alone. Open (OLIS) and closed (CLIS) lateral internal sphincterotomies are considered by many to be the treatment of choice for chronic anal fissures (CAF). The aim of this study was to compare the efficacy and clinical outcomes of different surgical techniques for treatment of CAF. Read More

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March 2014
4 Reads

Anal stretch plus fissurectomy for chronic anal fissure.

Authors:
A Cariati

Acta Chir Belg 2013 Sep-Oct;113(5):322-4

General Surgery, San Martino, IST Hospital, Genoa, Italy.

Introduction: Anal fissure is a common disease. Usually chronic anal fissures are managed medically. When conservative management fails, surgical treatment should be considered. Read More

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January 2014
13 Reads

Medical and surgical treatment of haemorrhoids and anal fissure in Crohn's disease: a critical appraisal.

BMC Gastroenterol 2013 Mar 11;13:47. Epub 2013 Mar 11.

Department of Surgery, University Hospital Tor Vergata, Viale Oxford 81, Rome 00133, Italy.

Background: The principle to avoid surgery for haemorrhoids and/or anal fissure in Crohn's disease (CD) patients is still currently valid despite advances in medical and surgical treatments. In this study we report our prospectively recorded data on medical and surgical treatment of haemorrhoids and anal fissures in CD patients over a period of 8 years.

Methods: Clinical data of patients affected by perianal disease were routinely and prospectively inserted in a database between October 2003 and October 2011 at the Department of Surgery, Tor Vergata University Hospital, Rome. Read More

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http://dx.doi.org/10.1186/1471-230X-13-47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602071PMC
March 2013
4 Reads

Comparative study of glyceryl trinitrate ointment versus surgical management of chronic anal fissure.

Indian J Surg 2011 Aug 8;73(4):268-77. Epub 2011 May 8.

Department of General Surgery, Fr. Muller Medical College Hospital, Kankanady, Mangalore, 575002 (D.K.) Karnataka India.

Chronic Anal Fissure (CAF) is common perineal condition and well-known painful entity. Standard surgical treatment even though available, may require long hospital stay and sometimes have worrying complications like anal incontinence. So non-surgical treatment, Glyceryl Trinitrate has been shown to be an effective for chronic anal fissure. Read More

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http://dx.doi.org/10.1007/s12262-011-0239-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144351PMC
August 2011
5 Reads

Sphincter-sparing anal-fissure surgery: a 1-year prospective, observational, multicentre study of fissurectomy with anoplasty.

Colorectal Dis 2013 Mar;15(3):359-67

Unité de Proctologie Médico-Chirurgicale, Hôpital Bichat-Claude Bernard, AP-HP, Paris, France.

Aim: Internal sphincterotomy is the standard surgical treatment for chronic anal fissure, but is frequently complicated by anal incontinence. Fissurectomy is proposed as an alternative technique to avoid sphincter injury. We describe 1-year outcomes of fissurectomy. Read More

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http://dx.doi.org/10.1111/j.1463-1318.2012.03176.xDOI Listing
March 2013
31 Reads

Value of cytologic Papanicolaou smears and polymerase chain reaction screening for human papillomavirus DNA in detecting anal intraepithelial neoplasia: comparison with histology of a surgical sample.

Cancer 2012 Dec 6;118(24):6031-8. Epub 2012 Jun 6.

Proctology Service-Medical Intervention, Diaconesses-Croix St Simon Group Hospitals, Paris, France.

Background: The performance of cytologic screening and its correlation with histology and polymerase chain reaction (PCR) detection of human papillomavirus (HPV) DNA have not been evaluated in populations with a low prevalence of anal intraepithelial neoplasia (AIN). The objective of the current study was to analyze the significance of abnormal smears relative to the histology and PCR detection of HPV DNA.

Methods: A cytologic smear and a viral sample were taken in 300 consecutive patients undergoing surgery (Milligan-Morgan hemorrhoidectomy and/or fissurectomy) who gave their informed consent. Read More

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http://dx.doi.org/10.1002/cncr.27671DOI Listing
December 2012
22 Reads

Manometric evaluation of internal anal sphincter after fissurectomy and anoplasty for chronic anal fissure: a prospective study.

Am Surg 2012 May;78(5):523-7

General Surgery Unit, Department of Surgical and Oncological Sciences, University of Palermo, Palermo, Italy.

Chronic anal fissure (CAF) is a common painful clinical disease and its pathogenesis remains poorly understood. After failure of pharmacological therapy, that is the first-line treatment, surgical sphincterotomy remains the treatment of choice although it is followed by a high rate of anal incontinence resulting from the sphincter damage; therefore, the research of a sphincter-saving surgical option has become an important goal. The aim of this study was to evaluate the manometric modifications and the incidence of anal incontinence after fissurectomy and anoplasty with advancement skin flap in patients affected by CAF with hypertonia of the internal anal sphincter (IAS). Read More

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May 2012
21 Reads

Advancement flap in the management of chronic anal fissure: a prospective study.

Updates Surg 2012 Jun 10;64(2):101-6. Epub 2012 Apr 10.

Department of Surgical and Oncologic Science, University of Palermo, Palermo, Italy.

Lateral internal sphincterotomy is the surgical treatment of choice of chronic anal fissure after failure of conservative measures. Several randomized trials identified an overall risk of incontinence of 10 % mostly for flatus. Fissurectomy is the most commonly used procedure to preserve the integrity of the anal sphincters. Read More

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http://dx.doi.org/10.1007/s13304-012-0147-2DOI Listing
June 2012
10 Reads

Operative procedures for fissure in ano.

Cochrane Database Syst Rev 2011 Nov 9(11):CD002199. Epub 2011 Nov 9.

Department of General Surgery, Northern General Hospital, Sheffield, UK.

Background: Reports of direct comparisons between operative techniques for anal fissure are variable in their results. These reports are either subject to selection bias (in non-randomized studies) or observer bias (in all studies) or have inadequate numbers of patients enrolled to answer the question of efficacy.

Objectives: To determine the best technique for fissure surgery. Read More

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http://dx.doi.org/10.1002/14651858.CD002199.pub4DOI Listing
November 2011
4 Reads

Five-year results of fissurectomy for chronic anal fissure: low recurrence rate and minimal effect on continence.

Colorectal Dis 2012 Aug;14(8):997-1000

Department of Colorectal Surgery, Zaans Medical Centre, Zaandam, The Netherlands.

Aim: The aim of the study was to determine the long-term outcome, recurrence rate and faecal incontinence score after fissurectomy for chronic anal fissure (CAF) not responding to conservative treatment.

Method: Fifty-three consecutive patients (29 women) who underwent fissurectomy for a medically resistant CAF between 1998 and 2005 were included in the study. At a minimum follow-up of 5 years a standardized questionnaire was sent to all patients, assessing recurrence, satisfaction with the operation (on a scale of 0-10) and faecal continence (Vaizey score, 0-24). Read More

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http://dx.doi.org/10.1111/j.1463-1318.2011.02840.xDOI Listing
August 2012
3 Reads

Identifying the best therapy for chronic anal fissure.

World J Gastrointest Pharmacol Ther 2011 Apr;2(2):9-16

Mariusz H Madalinski, NHS Lothian-University Hospitals Division, Edinburgh EH4 2XU, United Kingdom.

Chronic anal fissure (CAF) is a painful tear or crack which occurs in the anoderm. The optimal algorithm of therapy for CAF is still debated. Lateral internal sphincterotomy (LIS) is a surgical treatment, considered as the 'gold standard' therapy for CAF. Read More

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http://dx.doi.org/10.4292/wjgpt.v2.i2.9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091162PMC
April 2011
3 Reads

Medium-term results of anal advancement flap compared with lateral sphincterotomy for the treatment of anal fissure.

Int J Colorectal Dis 2011 Sep 12;26(9):1211-4. Epub 2011 May 12.

Southend General Hospital, Prittlewell Chase, Westcliff-on-Sea, SS0 0RY, Essex, UK.

Introduction: Anal fissure is associated with anal pain and bleeding. Lateral internal sphincterotomy (LIS) has been a common form of surgical management. This can however cause incontinence and hence an equally effective alternative without this risk would be ideal. Read More

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http://link.springer.com/10.1007/s00384-011-1234-4
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http://dx.doi.org/10.1007/s00384-011-1234-4DOI Listing
September 2011
2 Reads

[Mucosa advancement flap anoplasty in treatment of chronic anal fissures: a prospective, multicenter, randomized controlled trial].

Zhong Xi Yi Jie He Xue Bao 2011 Apr;9(4):402-9

Department of Coloproctology, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China.

Background: Anal fissure is one of the most common anal-rectum diseases, and approximately 10 percent patients with chronic anal fissure ultimately receive surgery. Relieving postoperative pain and protecting functions of the sphincter are central issues for coloproctologists.

Objective: To evaluate the efficacy and safety of anoplasty in the treatment of chronic anal fissures. Read More

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April 2011
11 Reads

Innovations in chronic anal fissure treatment: A systematic review.

World J Gastrointest Surg 2010 Jul;2(7):231-41

Aaron Poh, Kok-Yang Tan, Department of Surgery, Khoo Teck Puat Hospital, Singapore 768828, Singapore.

A chronic anal fissure is a common perianal condition. This review aims to evaluate both existing and new therapies in the treatment of chronic fissures. Pharmacological therapies such as glyceryl trinitrate (GTN), Diltiazem ointment and Botulinum toxin provide a relatively non-invasive option, but with higher recurrence rates. Read More

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http://dx.doi.org/10.4240/wjgs.v2.i7.231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999245PMC
July 2010
2 Reads

Prospective survey of secondary bleeding following anorectal surgery in a consecutive series of 1,269 patients.

Clin Res Hepatol Gastroenterol 2011 Jan;35(1):41-7

Hôpital Bagatelle, 201, rue Robespierre, 33401 Talence cedex, France.

Introduction: As little data is available about secondary bleeding after proctological surgery, we conducted a specific survey.

Patients And Methods: Patients operated between November 2008 and April 2009 were prospectively included. Patients were followed until last visit (day 21-28). Read More

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http://dx.doi.org/10.1016/j.gcb.2010.10.001DOI Listing
January 2011
2 Reads

Fissurectomy with posterior midline sphincterotomy for management of chronic anal fissure.

J Coll Physicians Surg Pak 2010 Apr;20(4):229-31

Department of Surgery, Liaquat University of Medical and Health Sciences, Jamshoro.

Objective: To determine the efficacy and safety of fissurectomy with posterior midline sphincterotomy in the management of chronic anal fissure in terms of symptomatic relief, complications and recurrence.

Study Design: Observational case-series.

Place And Duration Of Study: Department of Surgery, Liaquat University Hospital, Jamshoro/Hyderabad, for a period of 3 years from January 2005 to December 2007. Read More

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http://dx.doi.org/04.2010/JCPSP.229231DOI Listing
April 2010
3 Reads

Early results of fissurectomy and advancement flap for resistant chronic anal fissure without hypertonia of the internal anal sphincter.

Am Surg 2010 Feb;76(2):206-10

Department of Surgical and Oncological Science, Division of General Surgery, University of Palermo, Palermo, Italy.

The aim of this study was to assess the efficacy of fissurectomy with skin advancement flap in healing chronic anal fissures without hypertonia of the internal anal sphincter. Twenty-six consecutive patients who failed healing after well-practiced topical medical therapy were enrolled. Anorectal manometry was performed preoperative and 6 months postoperatively. Read More

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February 2010
2 Reads

Conservative and surgical treatment of chronic anal fissure: prospective longer term results.

J Gastrointest Surg 2010 May 2;14(5):773-80. Epub 2010 Mar 2.

Department of Surgery, University of Rome Tor Vergata, Policlinico Tor Vergata, Chirurgia generale 6B Viale Oxford 81, 00133 Rome, Italy.

Introduction: The aim of this prospective study was to assess the efficacy of different medical treatments and surgery in the treatment of chronic anal fissure (CAF).

Patients And Methods: From January 2004 to March 2009, 311 patients with typical CAF completed the study. All patients were initially treated with 0. Read More

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http://dx.doi.org/10.1007/s11605-010-1154-6DOI Listing
May 2010
23 Reads

Fissurectomy combined with anoplasty and injection of botulinum toxin in treatment of anterior chronic anal fissure with hypertonia of internal anal sphincter: a pilot study.

Tech Coloproctol 2010 Mar 3;14(1):31-6. Epub 2010 Feb 3.

Department of Surgical and Oncological Science, Division of General Surgery, University of Palermo, Via Liborio Giuffrè no 5, Palermo, Italy.

Background: In patients affected by anterior chronic anal fissure (CAAF) with hypertonia of the internal anal sphincter (IAS), the role of IAS hypertonia remains unclear. The aim of this study was to evaluate the efficacy of fissurectomy combined with advancement flap and IAS injection of botulinum toxin in healing the CAAF with hypertonia of IAS resistant to medical therapy.

Methods: Ten consecutive patients were enrolled. Read More

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http://dx.doi.org/10.1007/s10151-009-0562-7DOI Listing
March 2010
5 Reads

Botulinum toxin A with fissurectomy is a viable alternative to lateral internal sphincterotomy for chronic anal fissure.

Am Surg 2009 Oct;75(10):925-8

Department of Surgery, Kaiser Permanente, Los Angeles, California 90027, USA.

Lateral internal sphincterotomy (LIS) is the gold standard surgical treatment for anal fissure. However, it carries potential complications, including fecal incontinence. The goal of this retrospective study was to compare the outcome of botulinum toxin A injection coupled with fissurectomy ([BTX + FIS) versus LIS. Read More

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October 2009
6 Reads

Fissurectomy and anal advancement flap for anterior chronic anal fissure without hypertonia of the internal anal sphincter in females.

Colorectal Dis 2010 Nov;12(11):1127-30

Division of General Surgery, Department of Surgical and Oncological Science, University of Palermo, Palermo, Italy.

Aim: Lateral internal sphincterotomy is considered the surgical treatment of choice for chronic anal fissure after failure of medical therapy but it risks continence. The aim of the study was to evaluate fissurectomy with advancement flap for anterior chronic anal fissure (CAAF) resistant to medical therapy.

Method: Sixteen women with CAAF without hypertonia of the internal anal sphincter, unresponsive to previous medical treatment, were included in the study. Read More

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http://dx.doi.org/10.1111/j.1463-1318.2009.02068.xDOI Listing
November 2010
3 Reads

Fissurectomy combined with botulinum toxin A injection for medically resistant chronic anal fissures.

Colorectal Dis 2010 Jul 13;12(7 Online):e163-9. Epub 2009 Oct 13.

Department of Surgery, Medisch Spectrum Twente, Enschede, The Netherlands.

Introduction: Chemical sphincterotomy, the use of pharmacological agents to reduce anal sphincter resting pressure, has become more and more popular in the treatment of chronic anal fissures (CAFs). It offers the possibility to avoid a lateral internal sphincterotomy and its associated risk of incontinence. In our hospital, patient with a chronic anal fissure are consecutively treated with isosorbide dinitrate 1% ointment, applied 6 times a day for 8 weeks, followed by diltiazem 2% ointment, applied 2 times a day for 8 weeks and Botulin Toxin A injections (Dysport; Ipsen, Hoofddorp, the Netherlands) in the internal anal sphincter. Read More

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http://dx.doi.org/10.1111/j.1463-1318.2009.02063.xDOI Listing
July 2010
2 Reads

A comparison between the results of fissurectomy and lateral internal sphincterotomy in the surgical management of chronic anal fissure.

J Gastrointest Surg 2009 Jul 5;13(7):1279-82. Epub 2009 May 5.

Shohada Hospital, Shahid Beheshti University of Medical Sciences and Health Services, Tajrish square, Tehran, Iran.

Background: We compare lateral internal sphincterotomy as an effective treatment of chronic fissure in ano to fissurectomy, which is as an alternative surgical treatment.

Methods: Sixty two consecutive patients were divided into two groups through sequential sampling. Thirty patients underwent fissurectomy and 32 underwent lateral internal sphincterotomy. Read More

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http://dx.doi.org/10.1007/s11605-009-0908-5DOI Listing
July 2009
5 Reads

A pilot comparative study of fissurectomy/diltiazem and fissurectomy/botulinum toxin in the treatment of chronic anal fissure.

Tech Coloproctol 2008 Dec 18;12(4):331-6; discussion 336. Epub 2008 Nov 18.

Wirral Colorectal Unit, Arrowe Park Hospital, Wirral, Merseyside, UK.

Background: Treatment of chronic anal fissure (CAF) by fissurectomy with botulinum toxin A (BTA) injection results in a healing rate of greater than 90%. BTA injection, however, can cause incontinence and perianal sepsis. The decrease in sphincter pressure following topical treatment with 2% diltiazem cream (DTC) is comparable to that following BTA injection but with potentially fewer complications and at less cost. Read More

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http://dx.doi.org/10.1007/s10151-008-0444-4DOI Listing
December 2008
3 Reads

A randomized clinical trial on the effect of oral metronidazole on wound healing and pain after anal sphincterotomy and fissurectomy.

Arch Iran Med 2008 Sep;11(5):550-2

Gastroenterohepatology Research Center, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

Chronic anal fissure is one of the most common causes of anal pain and surgical therapy is the treatment of choice. There is scarce information regarding the prophylactic effects of oral metronidazole on postoperative complications of anal fissure. The objective of this study was to determine the effects of metronidazole as a prophylactic measure for postoperative anal fissure complications. Read More

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September 2008
8 Reads

The long-term efficacy of fissurectomy and botulinum toxin injection for chronic anal fissure in females.

Dis Colon Rectum 2008 Oct 26;51(10):1589; author reply 1590. Epub 2008 Jul 26.

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http://dx.doi.org/10.1007/s10350-008-9419-9DOI Listing
October 2008
1 Read

Combined fissurectomy and botulinum toxin injection. A new therapeutic approach for chronic anal fissures.

Gastroenterol Clin Biol 2008 Jun-Jul;32(6-7):667-70. Epub 2008 May 12.

Department of Visceral and Transplantation Surgery, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.gcb.2008.03.013DOI Listing
October 2008
2 Reads

Fissurectomy for treatment of chronic anal fissures.

Dis Colon Rectum 2008 Jul 3;51(7):1163; author reply 1164. Epub 2008 May 3.

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http://dx.doi.org/10.1007/s10350-008-9273-9DOI Listing
July 2008
2 Reads

[Fistulas and fissures. Part II: fissures].

Authors:
W Heitland

Chirurg 2008 May;79(5):439-43

Klinikum Bogenhausen, Klinik für Visceral-, Thorax- und Gefässchirurgie, Städtisches Klinikum München GmbH, Englschalkinger Strasse 77, 81925 München.

Fissures in ano are linear ulcers situated in the anal canal and extending from the dentate line to the margin of the anus. They cause pain and spasms. Diagnosis is made by the history alone. Read More

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http://dx.doi.org/10.1007/s00104-008-1511-0DOI Listing
May 2008
5 Reads

The long-term efficacy of fissurectomy and botulinum toxin injection for chronic anal fissure in females.

Dis Colon Rectum 2008 Feb 4;51(2):239-43. Epub 2008 Jan 4.

The Northern General Hospital, Sheffield, United Kingdom.

Introduction: Healing rates for botulinum toxin injection for anal fissure may be improved if combined with fissurectomy. This procedure has a decreased risk of incontinence, which is particularly important in females. We investigated the long-term efficacy of fissurectomy and botulinum toxin injection for chronic resistant fissures in females. Read More

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http://dx.doi.org/10.1007/s10350-007-9161-8DOI Listing
February 2008
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Medical and surgical treatment of chronic anal fissure: a prospective study.

J Gastrointest Surg 2007 Nov 31;11(11):1541-8. Epub 2007 Aug 31.

Department of Surgery, University of Rome Tor Vergata, Policlinico Tor Vergata, Rome, Italy.

The aim of this prospective study was to assess the efficacy of different medical treatments and surgery in the treatment of chronic anal fissure (CAF). From 1/04 to 09/06, 156 patients with typical CAF completed the study. All patients were treated with 0. Read More

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http://www.chirurgiacolorettale.eu/upload/CONF16/20130106/bo
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http://link.springer.com/content/pdf/10.1007/s11605-007-0255
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http://link.springer.com/10.1007/s11605-007-0255-3
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http://dx.doi.org/10.1007/s11605-007-0255-3DOI Listing
November 2007
10 Reads

Modern perspectives in the treatment of chronic anal fissures.

Ann R Coll Surg Engl 2007 Jul;89(5):472-8

Department of Surgery, Darent Valley Hospital, Dartford, Kent, UK.

Introduction: Anal fissures are commonly encountered in routine colorectal practice. Developments in the pharmacological understanding of the internal anal sphincter have resulted in more conservative approaches towards treatment. Simple measures are often effective for early fissures. Read More

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http://dx.doi.org/10.1308/003588407X202137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048592PMC
July 2007
2 Reads

[Treatment of anorectal diseases].

Authors:
A Herold

Praxis (Bern 1994) 2007 Feb;96(7):249-55

Enddarm-Zentrum Mannheim.

HAEMORRHOIDAL DISEASE: Stage orientated treatment of haemorrhoidal disease using conservative and operative measures provides high healing rates with low complication- and recurrence rates. ANAL FISSURE: Muscle relaxing ointments (Nitrates, Ca-channel-blocker) are the treatment of choice for chronic anal fissure. In cases of insufficiency fissurectomy provides high healing rates. Read More

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http://dx.doi.org/10.1024/1661-8157.96.7.249DOI Listing
February 2007
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Long-term follow-up after combined fissurectomy and Botox injection for chronic anal fissures.

Int J Colorectal Dis 2007 Sep 30;22(9):1077-81. Epub 2007 Jan 30.

Department for Visceral and Transplantation Surgery, University Hospital Zürich, Rämistrasse 100, 8091 Zurich, Switzerland.

Background And Aims: Chronic anal fissures are difficult to treat. The aim of this retrospective study was to determine the outcome of combined fissurectomy and injection of botulinum toxin Type A (BT).

Materials And Methods: Between January 2001 and August 2004, 40 patients (21 women), median age 37 years (range 18 to 57), underwent fissurectomy and BT injection. Read More

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http://dx.doi.org/10.1007/s00384-006-0261-zDOI Listing
September 2007
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[Treatment of chronic anal fissures: report of 31 cases].

Dakar Med 2002 ;47(2):164-7

Clinique Chirurgicale, Hôpital A Le Dantec Avenue Pasteur, BP 3001- Dakar Sénégal.

A prospective study evaluating the surgical technique used in the treatment of chronic anal fissures, which is fissurectomy, partial sphincterotomy and anoplasty, was carried out in University Teaching Hospital Dakar. Thirty one patients with chronic anal fissures (20 males and 11 females) with average age 38 years and mean consultation period of 3 years, were treated with this technique. The delay of healing was between 4 to 12 weeks for a mean period of six weeks with 27 cases healed before 2 months and 4 cases after. Read More

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April 2005
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Fissurectomy-botulinum toxin: a novel sphincter-sparing procedure for medically resistant chronic anal fissure.

Dis Colon Rectum 2004 Nov;47(11):1947-52

Department of Colorectal Surgery, John Radcliffe Hospital, Oxford, United Kingdom.

Background: Botulinum toxin heals only approximately one-half of glyceryl trinitrate-resistant chronic anal fissures, perhaps because chemical sphincterotomy alone treats internal sphincter spasm but not chronic fissure fibrosis. We aimed to assess whether a novel procedure, fissurectomy-botulinum toxin, improves the healing rate of medically resistant fissures over that achieved with botulinum toxin alone.

Methods: A prospective pilot study of chronic fissure patients failing medical therapy was undertaken. Read More

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November 2004
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Reinterventions after complicated or failed stapled hemorrhoidopexy.

Dis Colon Rectum 2004 Nov;47(11):1846-51

Coloproctology Unit, Villa Flaminia Hospital, Rome, Italy.

Background: Stapled hemorrhoidopexy has become increasingly popular over the past five years, mainly because of the assumption that it is associated with less pain. However, persistent tags and recurrence might represent a problem, because piles are not excised and severe complications requiring surgery have been occasionally reported. The aim of the present study is to analyze the causes for and the outcome of reintervention following either severely complicated or failed stapled hemorrhoidopexy. Read More

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November 2004
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Iatrogenic meningitis after lumbar puncture-a preventable health hazard.

J Hosp Infect 2004 Feb;56(2):119-24

Department of Neurology, Christian Medical College, Ludhiana 141008, Punjab, India.

Iatrogenic meningitis (IM) is a rare complication of diagnostic and therapeutic lumbar puncture (LP). This study includes cases of IM managed in the Departments of Neurology, of two referral hospitals, in India between January 1984 and April 2002. The diagnosis of IM was made when symptoms of meningitis occurred 24 h to 21 days after LP. Read More

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http://dx.doi.org/10.1016/j.jhin.2003.09.023DOI Listing
February 2004
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