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Accid Anal Prev 2018 Dec 11;123:243-255. Epub 2018 Dec 11.

Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Via Paradisa 2, 56126, Pisa, Italy.

Road traffic injuries represent a serious public health problem and are one of leading cause of death, injury and disability around the world. Road accidents are often caused by an accumulation of factors; however, drivers appear to be by far the most decisive one. The driver's behaviour is complex and depends on reflex (or involuntary) and voluntary driving actions. Read More

J Pharm Biomed Anal 2018 Dec 5;165:173-181. Epub 2018 Dec 5.

National Center of Mass Spectrometry in Changchun and Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry and Chemical Biology Laboratory, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China; University of Science and Technology of China, Hefei, 230026, China. Electronic address:

In this study, a novel analysis strategy for progressively targeted screening and characterization of drug ingredients from in vitro to in vivo was proposed based on ultra-high performance liquid chromatography-tandem mass spectrometry for comprehensive characterization of in vivo metabolic profile of Polygalae radix (PR). First, an in vitro chemical profile of PR was described with the assistance of UNIFI™ software. The characteristic neutral small molecule losses were summarized to distinguish different chemical structures in the PR extract. Read More

J Pharm Biomed Anal 2018 Dec 4;165:162-172. Epub 2018 Dec 4.

University of Rijeka, Department of Biotechnology, Centre for high-throughput technologies, Radmile Matejčić 2, 51000 Rijeka, Croatia. Electronic address:

Propolis is a complex biological matrix consisting mostly of plant resins and waxes, and in a small proportion of the herbal secondary metabolites, phenols. Phenols are components that are responsible for biological activities of propolis, however, their qualitative and quantitative composition is strongly influenced by climate and vegetation. Although studies on profiling of propolis samples from different countries have been carried out for some time propolis from Croatia is still not characterized till now. Read More

Anal Biochem 2018 Dec 11. Epub 2018 Dec 11.

The Key Laboratory of Bioactive Materials Ministry of Education, College of Life Science, Nankai University, Weijin Road No.94, Tianjin, 300071, China. Electronic address:

In this work, a novel enzyme-mimicking nanocomposite of Mn(II)-poly-L-histidine (PLH) functionalized carboxylated multi walled carbon nanotubes (CMWCNTs) was designed and synthesized. Based on the catalase-like activity of the nanocomposite, a non-enzymatic hydrogen peroxide (H2O2) biosensor was then established and explored for H2O2 electrochemical detection. The nanocomposite was characterized by Fourier transform infrared spectra, Raman spectroscopy, and transmission electron microscopy. Read More

Anal Biochem 2018 Dec 11. Epub 2018 Dec 11.

Key Lab of Process Analysis and Control of Sichuan Universities, Yibin University, Yibin, Sichuan, 644000, China. Electronic address:

The feasibility of using near-infrared (NIR) spectroscopy coupled with classifier ensemble for improving the diagnosis of colorectal cancer was explored. A total of 157 NIR spectra from the patients were recorded and partitioned into the training set and the test set. Four algorithms, i. Read More

Risk Anal 2018 Dec 14. Epub 2018 Dec 14.

Department of Civil and Urban Engineering, Connected Cities for Smart Mobility towards Accessible and Resilient Transportation (C2SMART) Center, and Center for Urban Science and Progress (CUSP), New York University, Brooklyn, NY, USA.

The widely used empirical Bayes (EB) and full Bayes (FB) methods for before-after safety assessment are sometimes limited because of the extensive data needs from additional reference sites. To address this issue, this study proposes a novel before-after safety evaluation methodology based on survival analysis and longitudinal data as an alternative to the EB/FB method. A Bayesian survival analysis (SARE) model with a random effect term to address the unobserved heterogeneity across sites is developed. Read More

Risk Anal 2018 Dec 14. Epub 2018 Dec 14.

Social and Environmental Research Institute, Northampton, MA, USA.

Over the past four decades, the promise of public participation to improve decisions, obtain legitimacy, and build capacity for risk decision making and management has had a mixed record. In this article, we offer a narrative of how public participation has evolved in the United States and we examine prospects for its future. We trace three forces that have had significant impact on practice: an emergent emphasis on democratic deliberation, a transition from dichotomous thinking about science versus politics to an integrated perspective, and the recognition that different parties to the decision-making process bring valid epistemological contributions. Read More

J Appl Behav Anal 2018 Dec 14. Epub 2018 Dec 14.

Hunter College.

Children with autism spectrum disorder are typically taught conditional discriminations using a match-to-sample arrangement. Consideration should be given to the temporal order in which antecedent stimuli (the sample and comparison stimuli) are presented during match-to-sample trials, as various arrangements have been used in the extant literature. The purpose of the current study was to compare the effects of four stimulus presentation orders on the acquisition of auditory-visual conditional discriminations. Read More

J Appl Behav Anal 2018 Dec 14. Epub 2018 Dec 14.

University of South Florida.

There is limited research using small-scale simulation in applied behavior analysis. We used small-scale simulation to train firearm safety skills to 3- to 5-year-old children and assessed whether the skills generalized to the natural environment through in situ assessment. Three participants completed the training, and all participants learned the safety skills from simulation training. Read More

Drug Test Anal 2018 Dec 12. Epub 2018 Dec 12.

UCLA Olympic Analytical Laboratory, Department of Pathology & Laboratory Medicine, Geffen School of Medicine, Los Angeles, California, USA.

Both AICAR and mannitol are prohibited for use in sports, but no decisive criteria that would guide anti-doping laboratories on data interpretation have been established so far. In an attempt to help harmonize reporting and management of analytical findings, reference population data collected for the US athletes are presented. Upon analysis of 12377 samples, mean urinary AICAR concentration was found to be 647 ± 365 ng/mL with median value of 574 ng/mL, 99 percentile at 1786 ng/mL and 99. Read More

Low Urin Tract Symptoms 2018 Dec 12. Epub 2018 Dec 12.

Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Objective: Urinary incontinence (UI) is a major prostate cancer (PCa) treatment-related morbidity. It has been reported that post-prostatectomy UI is related to the width of the pelvic floor muscles (PFM) and the length of the urethra. However, the details of these anatomical parameters are unknown. Read More

Am J Med Genet A 2018 Dec 12:e40530. Epub 2018 Dec 12.

Laboratoire de Génétique Médicale, Faculté de Médecine, Université de Strasbourg, Strasbourg cedex, France.

Anorectal anomalies (ARA) are common congenital anomalies. The etiology of ARA is unclear and its pathogenesis is controversial. Cases with ARA often have other non-ARA-associated congenital anomalies. Read More

J Appl Behav Anal 2018 Dec 12. Epub 2018 Dec 12.

University of Maryland, Baltimore County.

If particular parameters (e.g., reinforcer quality) are found to be preferred in a concurrent-operant arrangement, then these should be incorporated into interventions for maintaining skills in individuals with intellectual disabilities. Read More

Drug Test Anal 2018 Dec 12. Epub 2018 Dec 12.

Department of Forensic Pharmacology & Toxicology, Zurich Institute of Forensic Medicine, University of Zurich, Zürich, Switzerland.

Gamma-hydroxybutyrate (GHB) is a short-chain fatty acid that occurs naturally in the mammalian brain and that is prescribed as a medication against narcolepsy or used as a drug of abuse. Particularly, its use as a knock-out drug in cases of drug facilitated crimes is of major importance in forensic toxicology. Because of its rapid metabolism and resulting narrow detection windows (<12 h in urine), detection of GHB remains challenging. Read More

Risk Anal 2018 Dec 12. Epub 2018 Dec 12.

National Center for Atmospheric Research, Boulder, CO, USA.

As emphasis on interdisciplinary and convergent research grows, researchers and institutions can benefit from additional insights into how to build interdisciplinary integration within the research process. This article presents signs of successful interdisciplinary research and proposes strategies that researchers can implement to help create and sustain integration across fields. Drawing on the authors' experiences, other examples from hazards research, and the literature on interdisciplinarity, the article asserts that successful interdisciplinary research incorporates full intellectual participation by each contributing field, forming a multiway partnership. Read More

Phytochem Anal 2018 Dec 11. Epub 2018 Dec 11.

Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, P.R. China.

Introduction: Lycorine, one of the most common alkaloids in Lycoris spp., is believed to possess pharmacological activity.

Objective: To discover and identify lycorine-type alkaloids in the crude extracts of bulbs from six Lycoris spp. Read More

Phytochem Anal 2018 Dec 11. Epub 2018 Dec 11.

Department of Entomology, University of Wisconsin-Madison, Madison, WI, USA.

Introduction: Condensed tannins (CTs) are proanthocyanidin heteropolymers that are widely distributed among plants. Their biochemical properties are determined by molecular structure (e.g. Read More

Drug Test Anal 2018 Dec 9. Epub 2018 Dec 9.

UCLA Olympic Analytical Laboratory, Department of Pathology & Laboratory Medicine, Geffen School of Medicine, Los Angeles, California, USA.

At present, anti-doping laboratories use androsterone, a major urinary steroid metabolite, to evaluate completeness of the derivatization step. This is typically done by calculating the ratio of mono-trimethylsilyl (TMS) androsterone to the total mono- and di-TMS androsterone. Certain samples may show an elevated percentage of mono-TMS androsterone indicating a failed derivatization step. Read More

Anal Chem 2018 Dec 14. Epub 2018 Dec 14.

The quantification of multiple lipids with different contents in plasma membrane at single cells is significant, but challenging, for the investigation of lipid interactions and the role of the dominant protein transporters. In this paper, co-monitoring the alteration of low-content sphingomyelin (SM) and high-content cholesterol in plasma membrane atone living cell is realized using luminolelectrochemiluminescence (ECL) at the first time. The concentration of SM as low as 0. Read More

Surg Innov 2018 Dec 14:1553350618818924. Epub 2018 Dec 14.

1 Proctology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Background: Gatekeeper (GK) has shown to be safe and effective in patients with fecal incontinence (FI). We aimed to understand its mechanism of action by comparing pre- and post-implant change in the external anal sphincter (EAS) contractility.

Methods: Study of EAS contractility was conducted in 16 FI females (median age = 69 years) before and after implant of 6 GK prostheses. Read More

Anal Chem 2018 Dec 14. Epub 2018 Dec 14.

Department of Chemistry , University of Illinois at Urbana-Champaign , 600 South Mathews Avenue , Urbana , Illinois 61801 , United States.

Developing miniaturized and inexpensive detectors remains an important and practical goal for field-deployable monitoring of toxic gases and other bioactive volatiles. CO (a common toxic pollutant) and ethylene (the phytohormone primarily responsible for fruit ripening) share the capability of strong back-π-bonding to low-oxidation-state metal ions, which has proved important in the development of metal-ion-based sensors for these gases. We report herein cumulative colorimetric sensor arrays based on Pd(II)-silica porous microsphere sensors and their application as an optoelectronic nose for rapid colorimetric quantification of airborne CO and ethylene. Read More

Anal Chem 2018 Dec 14. Epub 2018 Dec 14.

Thiophenol is the simplest aromatic thiol that is utilized for various applications in industry and agriculture. However, it should be used with care because thiophenol is readily absorbed into the human body by inhalation and ingestion, which leads to serious internal injuries. Thus, there is an urgent need for real-time and accurate monitoring of thio-phenol. Read More

Anal Chem 2018 Dec 14. Epub 2018 Dec 14.

Siderophores are natural metal chelating agents that strongly control the biogeochemical metal cycles such as Fe in the environment. This article describes a new methodology to detect and quantify at the micromolar concentration the spatial distribution at millimetre scale of siderophores within the root's system. The "universal" CAS assay originally designed for bacterial siderophores detection and later designed for fungus was adapted here for diffusive equilibrium in thin film gel techniques (DET). Read More

Anal Chem 2018 Dec 14. Epub 2018 Dec 14.

Ratiometric electrochemiluminescence (ECL) has attracted special focus in biological analysis field because it could eliminate the environmental interference to gain precise measurement. Herein, a dual-wavelength ratiometric ECL biosensor was designed for detection of cardiac troponin I (cTnI), where (4,4'-dicarboxylicacid-2,2'-bipyridyl) ruthenium(II) (Ru(dcbpy)32+) and Au nanoparticles loaded graphene oxide/polyethyleneimine (GPRu-Au) nanomaterial acts as an acceptor, and Au nanoparticles modified graphitic phase carbon nitride nanosheets composite (Au-CNN) acts as donor. Au-CNN shows high and steady ECL signal centered at 455 nm, which is well matched with the adsorption of GPRu-Au, thereby a high efficient electrochemiluminescent resonance energy transfer (ECL-RET) sensing platform is designed. Read More

Comput Anal Images Patterns 2017 28;10425:455-461. Epub 2017 Jul 28.

University of Seville, Spain.

This is an experimental paper in which we introduce the possibility to analyze and to synthesize 3D medical images by using multi-variate Gabor frames with Gaussian windows. Our purpose is to apply a space-variant filter-like operation in the space-frequency domain to correct medical images corrupted by different types of acquisitions errors. The Gabor frames are constructed with Gaussian windows sampled on non-separable lattices for a better packing of the space-frequency plane. Read More

Big Data Anal Knowl Discov (2017) 2017 Aug 3;10440:149-163. Epub 2017 Aug 3.

ECE, Northeastern University, Boston, USA.

We consider data analytics workloads on distributed architectures, in particular clusters of commodity machines. To find a job partitioning that minimizes running time, a cost model, which we more accurately refer to as makespan model, is needed. In attempting to find the simplest possible, but sufficiently accurate, such model, we explore piecewise linear functions of input, output, and computational complexity. Read More

Anal Chem Insights 2011 1;6:15-20. Epub 2011 Mar 1.

Department of Chemistry, Payame Noor University of Ilam, Iran.

The present study describes a simple and highly selective method for separation, preconcentration and spectrophotometric determination of extremely low concentrations of lead. It is based on flotation of a complex of Pb ions and Alizarin yellow between aqueous and -hexane interface at pH = 6. The proposed procedure is also applied for determination of lead in both tap water and prepared sea water samples. Read More

Front Public Health 2018 27;6:342. Epub 2018 Nov 27.

Collaboration for Evidence, Research and Impact in Public Health, School of Public Health, Curtin University, Bentley, WA, Australia.

Since the emergence of the HIV pandemic in the 1980s, high rates of condom use for penetrative sex have been reported among sex workers in Australia. The sex industry in Australia and elsewhere has changed over the previous decade with increasing proportions of sex workers working privately and lower proportions of sex workers working in brothels. There has also been some evidence of reductions in condom use, particularly during penetrative oral sex. Read More

JFMS Open Rep 2018 Jul-Dec;4(2):2055116918815323. Epub 2018 Dec 3.

Department of Clinical Sciences and Advanced Medicine, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA, USA.

Case Summary: A 15-year-old female spayed domestic shorthair cat was presented for hyporexia and acute development of L4-Cd myelopathy (urinary incontinence, pelvic limb paresis with hyporeflexia and absent tail tone). Humane euthanasia was elected owing to the rapid neurological deterioration and necropsy was performed. Post-mortem examination identified a right-sided anal sac mass and medial iliac lymphadenopathy. Read More

J Multivar Anal 2018 Jul 15;166:282-299. Epub 2018 Mar 15.

Department of Statistics and Operations Research, Department of Genetics, Department of Biostatistics, Carolina Center for Genome Sciences, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, NC 27599, USA.

Large-margin classifiers are powerful techniques for classification problems. Although binary large-margin classifiers are heavily studied, multicategory problems are more complicated and challenging. A common approach is to construct different decision functions for a -class problem with a sum-to-zero constraint. Read More

Anal Chem 2018 Dec 14. Epub 2018 Dec 14.

The mitochondrial membrane potential (MMP) definitely reflects mitochondrial function. Thus, it is very essential to found a physical parameter as MMP indicator. At present, available parameters are either fluorescent intensity of monochromatic probes such as rhodamine 123 or a ratio of fluorescent intensity at different wavelengths of dual-color dyes such as JC-1, but the inconvenience in practice as well as serious effect of loading concentrations on experimental results limited their application. Read More

J Pharm Biomed Anal 2018 Nov 30;165:155-161. Epub 2018 Nov 30.

EBSI Team, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), Université de Nantes, CNRS, UMR 6230, BP 92208 - 2, rue de la Houssinière, 44322, Nantes, France. Electronic address:

Authentication of natural products is of major relevance in the context of manufactured drugs or herbal supplements since such active products generate a lucrative market. The analytical method to identify and quantify valuable natural products is critical for quality control and product assignment of herbal supplements. In this framework, we propose to apply a recently developed quantitative 2D NMR approach called Q QUIPU (Quick QUantItative Perfected and pUre shifted) in combination with 1D H NMR capable to access the concentration of three major alkaloids, berberine, β-hydrastine and canadine, in the root extract of goldenseal (Hydrastis canadensis), one of the 20 most popular herbal supplements used worldwide. Read More

J Pharm Biomed Anal 2018 Dec 3;165:147-154. Epub 2018 Dec 3.

KU Leuven, University of Leuven, Department of Pharmaceutical and Pharmacological Sciences, Pharmaceutical Analysis, Herestraat 49, O&N2, PB923, B-3000, Leuven, Belgium. Electronic address:

In this study, an improved liquid chromatographic (LC) method for the analysis of tylosin and its impurities has been developed. A Kinetex EVO C18 column (150 × 4.6 mm, 2. Read More

Anal Biochem 2018 Dec 10. Epub 2018 Dec 10.

China National Tobacco Quality Supervision and Test Center, Zhengzhou, 450001, China. Electronic address:

Profiling of carboxyl-containing metabolites in smokers and non-smokers provides insight into the smoking-related biological events and causal relationships between exposure and adverse events. However, more comprehensive analysis of carboxyl-containing metabolites in bio-matrices with high sensitivity and accuracy is challenging. In this work, stable isotope labeling in combination with liquid chromatography-tandem mass spectrometry was used for untargeted profiling and relative quantification of carboxyl-containing metabolites in plasma of smokers and non-smokers. Read More

Anal Biochem 2018 Dec 10. Epub 2018 Dec 10.

Department Cell Biology, Harvard Medical School, USA.

Tuberculosis affects about 100 million people worldwide and causes nearly 2 million deaths annually. It has been estimated that one third of all humans is infected with latent Mycobacterium tuberculosis (Mtb). Moreover, Mtb has become increasingly resistant to available antibiotics. Read More

Dis Colon Rectum 2018 Dec 12. Epub 2018 Dec 12.

Department of Obstetrics, Gynaecology & Neonatology, Sydney Medical School Nepean, The University of Sydney, Kingswood, NSW, Australia.

Background: Obstetric anal sphincter injury is the primary modifiable risk factor for anal incontinence in women. Currently, endoanal ultrasound is most commonly used to detect residual anal sphincter defects after childbirth. Translabial ultrasound has recently been introduced as a noninvasive alternative. Read More

Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2018 Dec 13:1-13. Epub 2018 Dec 13.

a Joint Research Centre , European Commission , Geel , Belgium.

The production of certified reference materials requires the application of highly accurate methods for characterisation. A gas chromatography-isotope dilution mass spectrometry method, setting ambitious performance criteria, was developed for eight selected pesticides in soybeans. Pressurised liquid extraction was followed by automated gel-permeation chromatography and solid-phase extraction clean-up. Read More

Anal Chem 2018 Dec 13. Epub 2018 Dec 13.

Strong orthogonality to mass spectrometry makes differential ion mobility spectrometry (FAIMS) a powerful tool for isomer separations. However, high FAIMS resolution and 2-D FAIMS/MS peak capacity were overall achieved only with buffers rich in He or H2. That obstructed coupling to Fourier-transform mass spectrometers operating in ultrahigh vacuum, but exceptional m/z resolution and accuracy of FTMS are indispensable for frontline biological and environmental applications. Read More

Anal Chem 2018 Dec 13. Epub 2018 Dec 13.

Myeloid-derived growth factor (MYDGF in humans, Mydgf in mice) is a secreted protein with previously unknown biological functions. In a recent study, Mydgf was shown to mediate cardiac repair after acute myocardial infarction (MI) in mice. Lack of a sensitive assay to measure MYDGF in the circulation has hampered its further investigation. Read More

Anal Chem 2018 Dec 13. Epub 2018 Dec 13.

Anal Chem 2018 Dec 13. Epub 2018 Dec 13.

A near-infrared light (NIRL)-activated ratiometric photoelectrochemical (PEC) aptasensor was fabricated for detection of carcinoembryonic antigen (CEA) coupling with upconversion nanoparticles (UCNPs)-semiconductor nanocrystals-based spatial-resolved technique on a homemade 3D printing device in which a self-regulating integrated electrode was designed for dual signal readout. The as-prepared NaYF4:Yb, Er UCNPs@CdTe nanocrystals were initially assembled on two adja-cent photoelectrodes, then CEA aptamer 1 (A1) and capture DNA (CA) were modified onto two working photoelectrodes (WP1 and WP2) through covalent binding, respectively, and then gold nanoparticle-labeled CEA aptamer 2 (Au NP-A2) were immobilized on the surface of functional WP2 for the formation of double-stranded DNA. Upon target CEA introduction, the various concentrations of CEA were captured on the WP1, whereas the binding of the CEA with Au NP-A2 could be re-leased from the WP2 thanks to the highly affinity of CEA toward A2. Read More

Anal Chem 2018 Dec 13. Epub 2018 Dec 13.

Developing a convenient method able to discriminate among different types of DNA nucleotides within a target sequence of the human genome is extremely challenging. We herein report an artificial ferrocene-base (Fe-base) that was synthesized and incorporated into different loci of a DNA strand. The Fe-base replacement on a nucleobase can interact with DNA bases and efficiently discriminate among A, T, G, C DNA bases of the complementary locus based on interacting electrochemical properties. Read More

Anal Chem 2018 Dec 13. Epub 2018 Dec 13.

A new analytical all-solid-state platform for intradermal potentiometric detection of potassium in interstitial fluid is presented here. Solid microneedles are modified with different coatings and polymeric membranes to prepare both the potassium-selective electrode and reference electrode needed for the potentiometric readout. These microneedle-based electrodes are then fixed in an epidermal patch suitable for insertion into the skin. Read More

Anal Chem 2018 Dec 13. Epub 2018 Dec 13.

The laser induced breakdown spectroscopy (LIBS) experiment with a unique double pulse setup and operational procedure in low pressure (3 kPa) He ambient gas is performed for the study on the detection of light elements such as hydrogen (H) and deuterium (D) as well as elements of high excitation energies such as fluorine (F) and chlorine (Cl) which are usually difficult to be detected using ordinary LIBS technique. A nanosecond (ns) Nd:YAG laser operated in its fundamental wavelength with energy of 54 mJ is focused onto the Al target to generate the He plasma. Another picosecond (ps) Nd:YAG laser operated in its fundamental wavelength with energy of 2 mJ is focused onto the sample surface and activated 2 µs before the operation of ns laser. Read More

Anal Chem 2018 Dec 13. Epub 2018 Dec 13.

A novel amphiphile with cytosine moiety, which self-assembles into liposomes can be used to detect silver ions in water. The coordination of Ag+ ion increases membrane rigidity, which enhance the fluorescence of a common reporter. Ag+ can be sensed even at trace concentration (3 ppb) with great specificity over other metals ions. Read More

Anal Bioanal Chem 2018 Dec 12. Epub 2018 Dec 12.

School of Pharmacy, Shenyang Pharmaceutical University, P.O. Box 54, 103 Wenhua Road, Shenyang, 110016, Liaoning, China.

A simple and efficient method combining solid-phase extraction (SPE) with homogeneous liquid-liquid microextraction (HLLME) has been developed for fast pretreatment of chloramphenicol (CAP) from water samples prior to determination by high-performance liquid chromatography-ultraviolet detection. Oasis HLB sorbent was chosen for SPE. In HLLME, N,N-dimethylcyclohexylamine was used as a CO-triggered switchable solvent that could switch reversibly between hydrophilic and hydrophobic forms. Read More

Anal Bioanal Chem 2018 Dec 12. Epub 2018 Dec 12.

Department of Physical and Analytical Chemistry, Faculty of Chemistry, University of Oviedo, C/ Julian Claveria, 8, 33006, Oviedo, Spain.

Anal Bioanal Chem 2018 Dec 12. Epub 2018 Dec 12.

Institute of Translational Medicine, Nanchang University, Nanchang, 330088, Jiangxi, China.

A simple, rapid, and effective colorimetric assay for the detection of uric acid (UA) has been built, using the MoS nanoflakes-catalyzed 3,3',5,5'-tetramethylbenzidine (TMB)-HO system. In the presence of oxygen and uricase, uric acid was oxidized specifically to produce HO. MoS nanoflakes synthesized by hydrothermal reaction could catalyze the oxidation of TMB by HO, and engendering the colorimetric signal. Read More

Lifetime Data Anal 2018 Dec 12. Epub 2018 Dec 12.

Department of Applied Mathematics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong.

We consider the semiparametric regression of panel count data occurring in longitudinal follow-up studies that concern occurrence rate of certain recurrent events. The analysis of panel count data involves two processes, i.e, a recurrent event process of interest and an observation process controlling observation times. Read More

Heredity (Edinb) 2018 Dec 12. Epub 2018 Dec 12.

Facultad de Ciencias and Instituto de Ecología y Biodiversidad (IEB), Universidad de Chile, Santiago, Chile.

Although low levels of genetic structure are expected in highly widespread species, geographical and/or ecological factors can limit species distributions and promote population structure and morphological differentiation. In order to determine the effects of geographical isolation on population genetic structure and wing morphology, 281 individuals of the cosmopolitan odonate Pantala flavescens were collected from four continental (Central and South America) and five insular sites (Polynesian islands and the Maldives). COI sequences and eight microsatellite loci were used to characterize genetic diversity and genetic structure between and within locations. Read More