Search Our Scientific Publications & Authors

An Bras Dermatol 2022 May-Jun;97(3):366-368. Epub 2022 Apr 12.

Hospital Universitário Professor Polydoro Ernani de São Thiago, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.

The number of skin infections caused by atypical mycobacteria has increased in recent decades. They usually appear after contact with wounds and interruptions in the integrity of the skin. The present report describes a case of cutaneous infection by Mycobacterium marinum, in a young, immunocompetent patient, with a prolonged evolution, diagnosed through a skin lesion culture (from a spindle biopsy of the skin). Read More

An Bras Dermatol 2022 May-Jun;97(3):338-347. Epub 2022 Apr 2.

LIM56, Hospital das Clínicas, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil; Instituto de Saúde, Secretaria de Estado da Saúde, São Paulo, SP, Brazil.

Leprosy, a disease caused by Mycobacterium leprae, has polymorphic neurocutaneous manifestations strongly correlated with the host immune response. Peripheral neural damage can lead to sensory and motor losses, as well as deformities of the hands and feet. Both innate and acquired immune responses are involved, but the disease has been classically described along a Th1/Th2 spectrum, where the Th1 pole corresponds to the more limited presentations and the Th2 to the multibacillary ones. Read More

An Bras Dermatol 2022 May-Jun;97(3):291-297. Epub 2022 Apr 2.

Faculty of Medicine, Coimbra University Hospital, Coimbra, Portugal.

Background: Mohs Micrographic Surgery (MMS) is commonly used to treat high-risk basal cell carcinoma (BCC).

Objectives: Correlate clinicopathologic preoperative features with the number of MMS stages (primary endpoint) and margins (secondary endpoint) required for BCC complete excision.

Methods: We retrospectively analyzed BCCs treated by MMS in a 2-year period at the study's institution. Read More

An Bras Dermatol 2022 May-Jun;97(3):397-398. Epub 2022 Apr 2.

Dermatology Outpatient Clinic, Hospital Santa Casa de Misericórdia de Vitória, Vitória, ES, Brazil.

An Bras Dermatol 2022 May-Jun;97(3):402-404. Epub 2022 Apr 2.

Department of Anaesthesiology, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal.

An Bras Dermatol 2022 May-Jun;97(3):348-357. Epub 2022 Apr 2.

Department of Dermatology, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil.

Lichen planopilaris and frontal fibrosing alopecia are primary scarring alopecias where diagnosis can be suggested by clinical and trichoscopy features, especially in the early stages, but scalp biopsy is the standard exam for definitive diagnosis. Frontal fibrosing alopecia is considered a variant of lichen planopilaris, as the histopathological findings are similar, with a perifollicular lymphohistiocytic infiltrate, sometimes with a lichenoid pattern. A thorough clinical examination, trichoscopy and photographic documentation are essential to assess the evolution and therapeutic response. Read More

An Bras Dermatol 2022 May-Jun;97(3):284-290. Epub 2022 Apr 2.

Department of Dermatology, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Background: Adverse drug reactions are frequent, with cutaneous manifestations being the most common. In the hospital environment, the incidence of cutaneous drug reactions varies from 2% to 3%.

Objective: To analyze the profile of cutaneous drug reactions, relating clinical forms, suspected medications, histopathological alterations, systemic repercussions, treatment and course. Read More

An Bras Dermatol 2022 May-Jun;97(3):406-407. Epub 2022 Mar 21.

Department of Dermatology and Radiotherapy, Faculdade de Medicina, Universidade Estadual Paulista, Botucatu, SP, Brazil. Electronic address:

An Bras Dermatol 2022 May-Jun;97(3):400-402. Epub 2022 Mar 21.

Department of Dermatology, Hospital do Servidor Público Estadual de São Paulo, São Paulo, SP, Brazil.

An Bras Dermatol 2022 May-Jun;97(3):298-306. Epub 2022 Mar 21.

Department of Morphology, Universidade Federal do Amazonas, Manaus, AM, Brazil.

Background: Leishmaniasis is caused by an intracellular protozoan of the Leishmania genus. Mannose-binding lectin (MBL) is a serum complement protein and recognizes lipoprotein antigens in protozoa and the bacterial plasma membrane. Nucleotide variants in the promoter region and exon 1 of the MBL gene can influence its expression or change its molecular structure. Read More

An Bras Dermatol 2022 May-Jun;97(3):399-400. Epub 2022 Mar 20.

Department of Dermatology, Fukushima Medical University, Fukushima, Japan.

A 34-year-old female was referred to our department, complaining of multiple asymptomatic lesions that appeared two weeks previously. The patient had active nephritis with nephrotic syndrome and was treated with immunosuppressive therapies. Physical examination revealed multiple well-circumscribed rounds of flat brownish plaques with slightly elevated borders, some of which were covered by scales. Read More

An Bras Dermatol 2022 May-Jun;97(3):275-283. Epub 2022 Mar 18.

Discipline of Dermatology, Hospital de Clínicas, Universidade Estadual de Campinas, Campinas, SP, Brazil.

Immunobiologicals are a reality in current clinical practice and have increasingly gained space in the inflammatory disease scenario, especially in dermatology, with approved drugs for psoriasis, atopic dermatitis, and hidradenitis suppurativa, in addition to many others undergoing study. It is important for dermatologists to have knowledge of the medications approved in Brazil, for the best management of dermatoses, in addition to the fact that they represent hope for improvement in patients with chronic diseases. Read More

An Bras Dermatol 2022 May-Jun;97(3):379-382. Epub 2022 Mar 17.

Clínica de Dermatologia da Santa Casa de São Paulo, São Paulo, SP, Brazil.

An Bras Dermatol 2022 May-Jun;97(3):404-405. Epub 2022 Mar 17.

Clínica Privada de Dermatologia, Porto Alegre, RS, Brazil.

An Bras Dermatol 2022 May-Jun;97(3):358-361. Epub 2022 Mar 17.

Department of Dermatology, Hospital Universitario Puerta De Hierro, Majadahonda, Madrid, Spain.

Atopic dermatitis predisposes to skin infections, and on the other hand, some therapies used for atopic dermatitis may worsen viral infections whose lesions may be more diffuse and resistant to treatment. The authors present a patient with severe atopic dermatitis and disseminated molluscum contagiosum infection. The molluscum contagiosum did not clear with topical treatment, and it worsened her atopic dermatitis even more, so the authors started treatment with dupilumab. Read More

An Bras Dermatol 2022 May-Jun;97(3):362-365. Epub 2022 Mar 16.

Dermatology Clinic, Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil.

Anogenital herpes is one of the most prevalent sexually transmitted infections worldwide. It has several clinical manifestations, from cases of primary herpes infection to recurrent forms, among them chronic mucocutaneous herpes. This presentation is rare, characterized by a duration of more than four weeks, usually associated with immunosuppression and resistance to classic anti-herpetic treatment. Read More

An Bras Dermatol 2022 May-Jun;97(3):376-378. Epub 2022 Mar 14.

Laboratório Dermapat and Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, RS, Brazil.

A 73-year-old male patient developed a poorly differentiated squamous cell carcinoma in the anal canal nine months ago. He was treated with two cycles of 5-fluorouracil and cisplatin and concomitant radiotherapy (6 MeV linear photon accelerator, total dose of 54 Gy), with complete remission. Since forty-five days he presentes a painful perianal and intergluteal erosion with circinate pustular borders. Read More

An Bras Dermatol 2022 May-Jun;97(3):369-371. Epub 2022 Mar 11.

Neuroendocrinology Center, Complexo Hospitalar Santa Casa de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil; Postgraduate Program in Pathology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil. Electronic address:

Acromegaly is a rare disease characterized by changes in the bone and soft tissue systems, induced by excess growth hormone and insulin-like growth factor type 1. Among the skin lesions associated with acromegaly is cutis verticis gyrata, an hypertrophic, and coarse folding of the skin of the scalp, an association of uncommon incidence and unknown prevalence. This case report describes the case of a patient diagnosed with acromegaly at age 60 with previously unidentified cutis verticis gyrata. Read More

An Bras Dermatol 2022 May-Jun;97(3):332-337. Epub 2022 Mar 9.

Hospital São Paulo, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

This review is focused on updating knowledge about cholestatic pruritus. It summarizes clinical-epidemiological characteristics, pathophysiology, diagnostic approach, and evidence-based therapeutic recommendations regarding this form of pruritus. Pruritus is a frequent symptom that accompanies several liver diseases, particularly cholestatic ones. Read More

An Bras Dermatol 2022 May-Jun;97(3):372-375. Epub 2022 Mar 7.

Department of Pathology, Haydarpaşa Numune Training and Research Hospital, Hamidiye Medicine Faculty, University of Health Sciences, İstanbul, Turkey.

Alopecia areta (AA) and trichotillomania (TTM) are common causes for hair loss on the eyebrows. Yellow dots, vellus hairs, anisotrichosis, empty follicular openings, and black dots were observed in the present study's patients with AA. Split hairs, question mark hairs, broken hairs, flame hairs, black dots, hairs with different lengths, and hemorrhagic areas were found in the patients with TTM. Read More

An Bras Dermatol 2022 May-Jun;97(3):326-331. Epub 2022 Mar 7.

Department of Dermatology, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil.

Pseudomonas aeruginosa is a Gram-negative bacillus that frequently causes septicemia, abscesses and infections in skin wounds. Panniculitis caused by this microorganism is unusual and there are few well-documented cases, none of them in a patient with systemic lupus erythematosus. The present report describes an immunosuppressed patient with systemic lupus erythematosus who developed panniculitis caused by Pseudomonas aeruginosa, with a review of the literature on this rare presentation. Read More

An Bras Dermatol 2022 May-Jun;97(3):387-390. Epub 2022 Mar 7.

Department of Pathology, Assiut University Hospitals, Assiut University, Egypt. Electronic address:

An Bras Dermatol 2022 May-Jun;97(3):390-394. Epub 2022 Mar 7.

Department of Emergency Medicine, American University of Beirut, Beirut, Lebanon. Electronic address:

An Bras Dermatol 2022 May-Jun;97(3):321-325. Epub 2022 Mar 7.

Department of Dermatology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

Hand, foot, and mouth disease is a viral rickettsial disease caused by Coxsackievirus A16 and Enterovirus 71 in most cases. It is commonly seen in children under ten years old, who present oral enanthema and a macular, maculopapular, or vesicular rash on their hands and feet. However, an increase in cases caused by other viral serotypes was observed in adults in recent years with various clinical presentations and a troublesome diagnosis. Read More

An Bras Dermatol 2022 May-Jun;97(3):382-384. Epub 2022 Mar 7.

Department of Dermatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

An Bras Dermatol 2022 May-Jun;97(3):384-386. Epub 2022 Feb 28.

Department of Infectology, Dermatology, Diagnostic Imaging and Radiotherapy, Faculty of Medicine, Universidade Estadual Paulista, Botucatu, SP, Brazil. Electronic address:

An Bras Dermatol 2022 May-Jun;97(3):307-314. Epub 2022 Feb 28.

Postgraduate Program in Pathology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil; Faculty of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

Background: Atopic dermatitis is the most common inflammatory skin disease in childhood and has an important impact on quality of life, especially severe cases or those that are recalcitrant to treatments. Sensitization to allergens with the potential for allergic contact dermatitis is a factor associated with cases of recalcitrant atopic dermatitis. Understanding the relationship between atopic dermatitis, allergens, and allergic contact dermatitis is essential. Read More

An Bras Dermatol 2022 May-Jun;97(3):395-396. Epub 2022 Feb 24.

Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanging, China. Electronic address:

An Bras Dermatol 2022 May-Jun;97(3):315-320. Epub 2022 Feb 17.

Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Background: Vitiligo is a common disease with a high burden, and its recalcitrant type is unresponsive to current medical treatments. Autologous non-cultured and trypsinized melanocyte grafting, which is a simple and experience-based procedure, has been suggested for the treatment of vitiligo.

Objective: To assess autologous non-cultured and trypsinised melanocyte grafting in recalcitrant vitiligo. Read More

An Bras Dermatol 2022 Mar-Apr;97(2):263-264. Epub 2022 Feb 10.

Department of Dermatology, Fukushima Medical University, Fukushima, Japan.