741 results match your criteria Anaesthesia and Intensive Care Medicine [Journal]


Haloperidol and delirium in the ICU: the finger pointing to the moon.

Authors:
Nicola Latronico

Intensive Care Med 2018 Jun 23. Epub 2018 Jun 23.

Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.

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The 11th pitfall: thiamine deficiency.

Intensive Care Med 2018 Jun 22. Epub 2018 Jun 22.

Department of Anesthesia and Intensive Care, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.

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Cell-surface signatures of immune dysfunction risk-stratify critically ill patients: INFECT study.

Intensive Care Med 2018 05 7;44(5):627-635. Epub 2018 Jun 7.

MRC Centre for Inflammation Research, University of Edinburgh, 47 Little France Crescent, Edinburgh, Scotland, UK.

Purpose: Cellular immune dysfunctions, which are common in intensive care patients, predict a number of significant complications. In order to effectively target treatments, clinically applicable measures need to be developed to detect dysfunction. The objective was to confirm the ability of cellular markers associated with immune dysfunction to stratify risk of secondary infection in critically ill patients. Read More

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May 2018
1 Read

Antipathy against SDD is justified: No.

Intensive Care Med 2018 Jun 7. Epub 2018 Jun 7.

Intensive Care Medicine, University of Birmingham, Birmingham, UK.

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Conservative versus liberal oxygenation targets in critically ill children: the randomised multiple-centre pilot Oxy-PICU trial.

Intensive Care Med 2018 Jun 4. Epub 2018 Jun 4.

Clinical Trials Unit, Intensive Care National Audit and Research Centre (ICNARC), Napier House, High Holborn, London, UK.

Background: Oxygen saturation monitoring for children receiving respiratory support is standard worldwide. No randomised clinical trials have compared peripheral oxygen saturation (SpO) targets for critically ill children. The harm of interventions to raise SpO to > 94% may exceed their benefits. Read More

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Perioperative myocardial injury and the contribution of hypotension.

Intensive Care Med 2018 Jun 4;44(6):811-822. Epub 2018 Jun 4.

Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, 9500 Euclid Ave-P77, Cleveland, OH, 44195, USA.

Mortality in the month following surgery is about 1000 times greater than anesthesia-related intraoperative mortality, and myocardial injury appears to be the leading cause. There is currently no known safe prophylaxis for postoperative myocardial injury, but there are strong associations among hypotension and myocardial injury, renal injury, and death. During surgery, the harm threshold is a mean arterial pressure of about 65 mmHg. Read More

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Does this patient with thrombotic thrombocytopenic purpura have a cardiac involvement?

Intensive Care Med 2018 Jun 4;44(6):893-896. Epub 2018 Jun 4.

AP-HP, Saint-Louis Hospital, Medical Intensive Care Unit, Paris (LZ, EA), ECSTRA Team, Biostatistics and Clinical Epidemiology, UMR 1153 INSERM, Paris Diderot, Sorbonne University, Paris, France.

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The present and future of cardiac arrest care: international experts reach out to caregivers and healthcare authorities.

Intensive Care Med 2018 Jun 2;44(6):823-832. Epub 2018 Jun 2.

Medical ICU, Cochin Hospital (AP-HP), Paris-Cardiovascular-Research-Centre, INSERM U970 (Sudden Death Expertize Centre), Paris, France.

Purpose: The purpose of this review is to describe the epidemiology of out-of-hospital cardiac arrest (OHCA), disparities in organisation and outcome, recent advances in treatment and ongoing controversies. We also outline the standard of care that should be provided by the critical care specialist and propose future directions for cardiac arrest research.

Methods: Narrative review with contributions from international resuscitation experts. Read More

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Correction to: Impact of intravascular thrombosis on failure of radial arterial catheters in critically ill patients: a nested case-control study.

Intensive Care Med 2018 05;44(5):699-700

Clinical Research Centre and Division of Clinical Epidemiology, Department of Health and Community Medicine, Faculty of Medicine, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 6, 1211, Geneva 14, Switzerland.

Owing to an error in typesetting, Table 2 was not structured correctly. Read More

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Outcome in patients perceived as receiving excessive care across different ethical climates: a prospective study in 68 intensive care units in Europe and the USA.

Intensive Care Med 2018 May 28. Epub 2018 May 28.

Department of Geriatric Medicine, Ghent University Hospital, Ghent, Belgium.

Purpose: Whether the quality of the ethical climate in the intensive care unit (ICU) improves the identification of patients receiving excessive care and affects patient outcomes is unknown.

Methods: In this prospective observational study, perceptions of excessive care (PECs) by clinicians working in 68 ICUs in Europe and the USA were collected daily during a 28-day period. The quality of the ethical climate in the ICUs was assessed via a validated questionnaire. Read More

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May 2018
3 Reads

Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit.

Intensive Care Med 2018 May 17. Epub 2018 May 17.

Department of Intensive Care, University Medical Center, University Utrecht, Utrecht, The Netherlands.

Purpose: To document and analyse the decision to withhold or withdraw life-sustaining treatment (LST) in a population of very old patients admitted to the ICU.

Methods: This prospective study included intensive care patients aged ≥ 80 years in 309 ICUs from 21 European countries with 30-day mortality follow-up.

Results: LST limitation was identified in 1356/5021 (27. Read More

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May 2018
1 Read

Prevalence and risk factors related to haloperidol use for delirium in adult intensive care patients: the multinational AID-ICU inception cohort study.

Intensive Care Med 2018 May 16. Epub 2018 May 16.

Department of Intensive Care, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

Purpose: We assessed the prevalence and variables associated with haloperidol use for delirium in ICU patients and explored any associations of haloperidol use with 90-day mortality.

Methods: All acutely admitted, adult ICU patients were screened during a 2-week inception period. We followed the patient throughout their ICU stay and assessed 90-day mortality. Read More

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Management of cardiogenic shock complicating myocardial infarction.

Intensive Care Med 2018 May 16. Epub 2018 May 16.

Department of Internal Medicine/Cardiology, Heart Center Leipzig - University Hospital, Leipzig, Germany.

Up to 10% of acute coronary syndromes are complicated by cardiogenic shock (CS) with contemporary mortality rates of 40-50%. The extent of ischemic myocardium has a profound impact on the initial, in-hospital, and post-discharge management and prognosis in this patient population. Individualized patient risk assessment plays an important role in determining appropriate revascularization, drug treatment with inotropes and vasopressors, mechanical circulatory support, intensive care support of other organ systems, hospital level of care triage, and allocation of clinical resources. Read More

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May 2018
4 Reads

Impact of angiotensin-converting enzyme inhibitors or receptor blockers on post-ICU discharge outcome in patients with acute kidney injury.

Intensive Care Med 2018 May 15. Epub 2018 May 15.

Department of Anaesthesiology, Critical Care Medicine and Burn Unit, Saint Louis and Lariboisière University Hospitals, AP-HP, 2 rue A. Paré, 75010, Paris, France.

Purpose: Acute kidney injury (AKI) is associated with the activation of the renin-angiotensin system. Whether angiotensin-converting enzyme inhibitors (ACEi) or angiotensin-receptor blockers (ARB) improve outcome in patients recovering from AKI remains unexplored. The purpose was to investigate the association between prescription of ACEi/ARB at intensive care unit (ICU) discharge and 1-year outcome in patients recovering from AKI. Read More

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May 2018
1 Read

The prevalence of burnout.

Intensive Care Med 2018 May 15. Epub 2018 May 15.

Anesthesia and Intensive Care Department, Hôpital Cochin, Assistance Publique Hôpitaux de Paris, 27 rue du Faubourg Saint-Jacques, 75679, Paris, Cedex 14, France.

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Alternatives to the Swan-Ganz catheter.

Intensive Care Med 2018 Jun 3;44(6):730-741. Epub 2018 May 3.

Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium.

While the pulmonary artery catheter (PAC) is still interesting in specific situations, there are many alternatives. A group of experts from different backgrounds discusses their respective interests and limitations of the various techniques and related measured variables. The goal of this review is to highlight the conditions in which the alternative devices will suffice and when they will not or when these alternative techniques can provide information not available with PAC. Read More

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June 2018
4 Reads

Advances in critical care management of patients undergoing cardiac surgery.

Intensive Care Med 2018 Jun 30;44(6):799-810. Epub 2018 Apr 30.

Cardiothoracic Surgical Unit, Royal Prince Alfred Hospital, The University of Sydney, Sydney, Australia.

Cardiac surgery has been evolving to include minimally invasive, hybrid and transcatheter techniques. Increasing patient age and medical complexity means that critical care management needs to adapt and evolve. Recent advances have occurred in several areas, including ventilation, haemodynamics and mechanical circulatory support, bleeding and coagulation, acute kidney injury, and neurological management. Read More

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June 2018
1 Read

Unilateral pulmonary venous occlusion caused by a localized pericardial clot.

Intensive Care Med 2018 Apr 30. Epub 2018 Apr 30.

Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City, IA, USA.

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Gulliver's travels in the intensive care unit.

Intensive Care Med 2018 Apr 26. Epub 2018 Apr 26.

General Intensive Care Unit, Policlinico Paolo Giaccone, University of Palermo, Palermo, Italy.

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Expert statement for the management of hypovolemia in sepsis.

Intensive Care Med 2018 Jun 25;44(6):791-798. Epub 2018 Apr 25.

Department of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Hypovolemia is frequent in patients with sepsis and may contribute to worse outcome. The management of these patients is impeded by the low quality of the evidence for many of the specific components of the care. In this paper, we discuss recent advances and controversies in this field and give expert statements for the management of hypovolemia in patients with sepsis including triggers and targets for fluid therapy and volumes and types of fluid to be given. Read More

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Ten things ICU specialists need to know about direct oral anticoagulants (DOACs).

Intensive Care Med 2018 Apr 25. Epub 2018 Apr 25.

Department of Intensive Care 4131, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.

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Ted Kolobow.

Intensive Care Med 2018 05 16;44(5):551-552. Epub 2018 Apr 16.

Emeritus, University of Michigan, Ann Arbor, USA.

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May 2018
1 Read

Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study.

Intensive Care Med 2018 05 9;44(5):564-577. Epub 2018 Apr 9.

Keenan Research Centre for Biomedical Science, St Michael's Hospital, Toronto, Canada.

Purpose: To evaluate patients with resolved versus confirmed ARDS, identify subgroups with substantial mortality risk, and to determine the utility of day 2 ARDS reclassification.

Methods: Our primary objective, in this secondary LUNG SAFE analysis, was to compare outcome in patients with resolved versus confirmed ARDS after 24 h. Secondary objectives included identifying factors associated with ARDS persistence and mortality, and the utility of day 2 ARDS reclassification. Read More

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May 2018
6 Reads

Impact of intravascular thrombosis on failure of radial arterial catheters in critically ill patients: a nested case-control study.

Intensive Care Med 2018 05 2;44(5):553-563. Epub 2018 Apr 2.

Clinical Research Centre and Division of Clinical Epidemiology, Department of Health and Community Medicine, Faculty of Medicine, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 6, 1211, Geneva 14, Switzerland.

Purpose: The patency of arterial catheters is essential for reliable invasive blood pressure monitoring. We sought to determine whether radial catheter failures were associated with intravascular thrombosis in critically ill adult patients.

Methods: This unmatched case-control study was conducted within a prospective cohort of patients admitted to an intensive care unit. Read More

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May 2018
1 Read

Understanding spontaneous vs. ventilator breaths: impact and monitoring.

Intensive Care Med 2018 Mar 24. Epub 2018 Mar 24.

Translational Medicine, Departments of Critical Care Medicine and Anesthesia, Hospital for Sick Children, University of Toronto, Toronto, Canada.

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March 2018
1 Read

Successful repair of aortic dissection, but no more playing with the grandsons.

Authors:
Thomas Bein

Intensive Care Med 2018 Jun 17;44(6):929. Epub 2018 Mar 17.

Department of Anesthesia and Operative Intensive Care, University Hospital Regensburg, 93042, Regensburg, Germany.

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June 2018
1 Read

Ten false beliefs in neurocritical care.

Intensive Care Med 2018 Mar 15. Epub 2018 Mar 15.

Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, and CHU de Québec-Université Laval Research Center, Université Laval, Québec City, QC, Canada.

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March 2018
1 Read

New blood for old? High quality evidence that fresh red blood cells confer no benefit for critically ill patients.

Intensive Care Med 2018 04 14;44(4):506-508. Epub 2018 Mar 14.

Department of Intensive Care and Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Room G3-206, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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April 2018
1 Read

Have we averted deaths using venoarterial ECMO?

Intensive Care Med 2018 Mar 12. Epub 2018 Mar 12.

Department of Medicine, Columbia University College of Physicians and Surgeons/New York-Presbyterian Hospital, New York, NY, USA.

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March 2018
1 Read

Understanding cardiovascular physiology of ageing.

Intensive Care Med 2018 Jun 9;44(6):932-935. Epub 2018 Mar 9.

Department of Anaesthesia and Intensive Care, Prince of Wales Hospital, Chinese University, Hong Kong, People's Republic of China.

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June 2018
1 Read

Lung volumes and transpulmonary pressure are decreased with expiratory effort and restored with passive breathing in ARDS: a reapplication of the traditional Campbell diagram.

Intensive Care Med 2018 04 7;44(4):534-536. Epub 2018 Mar 7.

Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA.

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April 2018
1 Read

Fluid therapy in neurointensive care patients: ESICM consensus and clinical practice recommendations.

Intensive Care Med 2018 04 2;44(4):449-463. Epub 2018 Mar 2.

School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.

Objective: To report the ESICM consensus and clinical practice recommendations on fluid therapy in neurointensive care patients.

Design: A consensus committee comprising 22 international experts met in October 2016 during ESICM LIVES2016. Teleconferences and electronic-based discussions between the members of the committee subsequently served to discuss and develop the consensus process. Read More

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April 2018
2 Reads

The patient who fell off a skyscraper.

Intensive Care Med 2018 Feb 24. Epub 2018 Feb 24.

Department of Internal Medicine and Pneumology, High Dependency Unit, Umberto I Hospital, Turin, Italy.

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February 2018
2 Reads

Vascular-induced lung injury: another advocate for personalized ARDS management : Discussion on "Inspiratory preload obliteration may injure lungs via cyclical 'on-off' vascular flow".

Intensive Care Med 2018 04 15;44(4):540-541. Epub 2018 Feb 15.

Department of Critical Care Medicine, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.

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April 2018
1 Read
7.21 Impact Factor

Position paper for the organization of ECMO programs for cardiac failure in adults.

Intensive Care Med 2018 Jun 15;44(6):717-729. Epub 2018 Feb 15.

Division of Pulmonary, Allergy, and Critical Care, Columbia University College of Physicians and Surgeons/NewYork-Presbyterian Hospital, 622 W168th St, PH 8E, Room 101, New York, NY, 10032, USA.

Extracorporeal membrane oxygenation (ECMO) has been used increasingly for both respiratory and cardiac failure in adult patients. Indications for ECMO use in cardiac failure include severe refractory cardiogenic shock, refractory ventricular arrhythmia, active cardiopulmonary resuscitation for cardiac arrest, and acute or decompensated right heart failure. Evidence is emerging to guide the use of this therapy for some of these indications, but there remains a need for additional evidence to guide best practices. Read More

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June 2018
10 Reads

Second consensus on the assessment of sublingual microcirculation in critically ill patients: results from a task force of the European Society of Intensive Care Medicine.

Intensive Care Med 2018 03 6;44(3):281-299. Epub 2018 Feb 6.

Department of Anesthesiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Purpose: Hand-held vital microscopes (HVMs) were introduced to observe sublingual microcirculatory alterations at the bedside in different shock states in critically ill patients. This consensus aims to provide clinicians with guidelines for practical use and interpretation of the sublingual microcirculation. Furthermore, it aims to promote the integration of routine application of HVM microcirculatory monitoring in conventional hemodynamic monitoring of systemic hemodynamic variables. Read More

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March 2018
14 Reads

Should this elderly patient be admitted to the ICU?

Intensive Care Med 2018 Jan 22. Epub 2018 Jan 22.

Department of Anaesthesia and Intensive Care, Haukeland University Hospital, Bergen, Norway.

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January 2018
1 Read

Is there a single non-painful procedure in the intensive care unit? It depends!

Intensive Care Med 2018 04 19;44(4):528-530. Epub 2018 Jan 19.

Department of Anaesthesia and Critical Care Medicine, University of Montpellier Saint Eloi Hospital, 34295, Montpellier Cedex 5, France.

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April 2018
1 Read

Correction to: Polymyxin B-immobilized hemoperfusion and mortality in critically ill adult patients with sepsis/septic shock: a systematic review with meta-analysis and trial sequential analysis.

Intensive Care Med 2018 02;44(2):279-280

Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 2-124 Clinical Sciences Building, 8440-112 ST NW, Edmonton, Canada, T6G 2B7.

Owing to an oversight by the authors, Figure 2 in this article was not the version intended for publication. The correct Figure 2, reproduced here, features footnote symbols and Figure 2b includes three studies as described in the main text. Read More

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February 2018
6 Reads

Inspiratory preload obliteration may injure lungs via cyclical "on-off" vascular flow.

Intensive Care Med 2017 Dec 21. Epub 2017 Dec 21.

Department of Critical Care Medicine, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.

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December 2017
4 Reads

Age-associated blood pressure distributions in paediatric intensive care units differ from healthy children.

Intensive Care Med 2018 03 14;44(3):384-386. Epub 2017 Dec 14.

Paediatric Intensive Care Unit, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.

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March 2018
5 Reads

Adjuvant therapy in acute heart failure.

Intensive Care Med 2018 Jun 4;44(6):900-903. Epub 2017 Dec 4.

U942 Inserm, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.

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June 2018
6 Reads

Polymyxin B-immobilized hemoperfusion and mortality in critically ill adult patients with sepsis/septic shock: a systematic review with meta-analysis and trial sequential analysis.

Intensive Care Med 2018 02 4;44(2):167-178. Epub 2017 Dec 4.

Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 2-124 Clinical Sciences Building, 8440-112 ST NW, Edmonton, Canada, T6G 2B7.

Purpose: Polymyxin B-immobilized hemoperfusion (PMX-HP) is an adjuvant therapy for sepsis or septic shock that clears circulating endotoxin. Prior trials have shown that PMX-HP improves surrogate endpoints. We aimed to conduct an evidence synthesis to evaluate the efficacy and safety of PMX-HP in critically ill adult patients with sepsis or septic shock. Read More

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February 2018
8 Reads

What's new in prognostication after cardiac arrest: microRNAs?

Intensive Care Med 2018 Jun 20;44(6):897-899. Epub 2017 Nov 20.

Department of Anaesthesia and Intensive Care Medicine, Centre Hospitalier, Luxembourg, Luxembourg.

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June 2018
4 Reads

Understanding adrenal crisis.

Intensive Care Med 2018 05 26;44(5):652-655. Epub 2017 Oct 26.

Division of Endocrinology and Diabetology, Department of Internal Medicine I, University Hospital Wuerzburg, Würzburg, Germany.

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May 2018
4 Reads

Can this patient be safely weaned from RRT?

Intensive Care Med 2018 05 20;44(5):639-642. Epub 2017 Oct 20.

Intensive Care Unit, Surrey Perioperative Anaesthesia and Critical Care Collaborative Research Group, Royal Surrey County Hospital NHS Foundation Trust, Egerton Road, Guildford, UK.

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May 2018
3 Reads

Acute respiratory failure from esophageal dilatation.

Intensive Care Med 2018 Feb 11;44(2):246-248. Epub 2017 Oct 11.

Section of Surgery and Anesthesiology, Unit of Anesthesia, Intensive Care and Pain Therapy, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.

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February 2018
3 Reads

Focus on fluid therapy.

Intensive Care Med 2017 12 5;43(12):1907-1909. Epub 2017 Oct 5.

Department of Anesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

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December 2017
3 Reads