341,174 results match your criteria Anaesthesia and Intensive Care Medicine [Journal]


Safety of robotic-assisted gynecologic surgery and early hospital discharge in elderly patients.

Am J Obstet Gynecol 2018 Dec 14. Epub 2018 Dec 14.

New York University Langone Medical Center. Electronic address:

Background: A minimally invasive surgical approach has proven to decrease peri- and post-operative complications and shorten duration of hospital stay, however there is limited data evaluating the safety of robotic-assisted surgery and early hospital discharge in the elderly population. As age is a well-known, independent risk factor for peri-operative morbidity and gynecologists treat many elderly patients, this is an important area of study.

Objective: To evaluate discharge timing and surgical outcomes in elderly compared to younger patients undergoing robotic-assisted gynecologic surgery. Read More

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December 2018
1 Read

ICU Structure and Outcomes Following Traumatic Brain Injury.

Crit Care Med 2019 Jan;47(1):e68-e69

Division of Anaesthesia, University of Cambridge, Cambridge, United Kingdom Intensive Care National Audit & Research Centre, London, United Kingdom.

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January 2019

The authors reply.

Crit Care Med 2019 Jan;47(1):e66-e67

Department of Cardiology, Heart Institute (InCor), Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil Surgical Intensive Care Unit and Department of Anesthesiology, Heart Institute (InCor), Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy.

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January 2019

Pediatric Advance Care Plan. When Cure Is Not an Option.

Crit Care Med 2019 Jan;47(1):140-141

Department of Anesthesia and Pediatrics, West Virginia University Children's Hospital, West Virginia University, Morgantown, WV Department of Anesthesia, West Virginia University, Morgantown, WV.

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January 2019

In Reply: Encouraging a Bare Minimum While Striving for the Gold Standard: A Response to the Updated WHO-WFSA Guidelines.

Anesth Analg 2019 Jan;128(1):e13-e14

Department of Anesthesia & Perioperative Care University of California San Francisco, San Francisco, California University of Otago, Christchurch Hospital, Christchurch, New Zealand Services Organization and Clinical Interventions Unit (SCI), Service Delivery and Safety Department (SDS), Health Systems and Innovation (HIS), World Health Organization, Switzerland Department of Anaesthesiology, University of Auckland Department of Anaesthesia, Auckland City Hospital, Auckland, New Zealand.

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January 2019

Encouraging a Bare Minimum While Striving for the Gold Standard: A Response to the Updated WHO-WFSA Guidelines.

Anesth Analg 2019 Jan;128(1):e12-e13

Journalism, Specialist Anaesthetist, Department of Anaesthesia and Perioperative Medicine, The Alfred Hospital and Monash University, Melbourne, Australia Consultant Anesthesiologist, King Faisal Hospital and Program Director, College of Medicine and Health Sciences University of Rwanda Consultant Anesthesiologist, Addis Ababa University, Ethiopia Consultant Anesthesiologist, Maputo Pain Clinic, Mozambique Anesthesiologist, Dalhousie University, Halifax, Canada Managing Director, Diamedica, United Kingdom Specialist Anaesthetist, Hobart, Tasmania Professor Emeritus, Queen's University, Departments of Anesthesiology, Pediatrics and Physiology, Kingston, Ontario, Canada Professor, Departments of Anesthesiology and Surgery Division of Ambulatory Surgery, Director, Vanderbilt Anesthesia Global Health & Development, Director, Vanderbilt Global Anesthesia Fellowship Affiliate Faculty, Vanderbilt Institute for Global Health, Vanderbilt University School of Medicine and Vanderbilt University Medical Center.

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January 2019

Drug Diversion in the Anesthesia Profession: How Can Anesthesia Patient Safety Foundation Help Everyone Be Safe? Report of a Meeting Sponsored by the Anesthesia Patient Safety Foundation.

Anesth Analg 2019 Jan;128(1):e2-e4

Northeastern University, Boston, Massachusetts, Scott & White Temple Medical Center, Temple, Texas Parkdale Center for Professionals, Chesterton, Indiana Preferred Physicians Medical, Overland Park, Kansas The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, Institute for Safe Medication Practices, Horsham, Pennsylvania.

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January 2019

Sensory Restoration of the Facial Region.

Ann Plast Surg 2018 Dec 13. Epub 2018 Dec 13.

From the Department of Plastic Surgery, University of Tennessee Health Science Center, Memphis, TN.

Normal sensitivity of the face is very important for preserving its integrity and function as an efferent source of information for the brain. The trigeminal nerve, which is the largest cranial nerve, conducts most of facial sensory function through its 3 branches: the ophthalmic nerve (V1), the maxillary nerve (V2), and the mandibular nerve (V3). The trigeminal nerve may be damaged by a variety of etiologies including inflammatory disorders, brain tumor resection, trauma, iatrogenic injury, or congenital anomalies. Read More

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December 2018

Adductor Canal Block Versus Femoral Nerve Block for Pain Control After Anterior Cruciate Ligament Reconstruction: A Prospective Randomized Trial.

Am J Sports Med 2018 Dec 17:363546518815874. Epub 2018 Dec 17.

Department of Orthopaedic Surgery, Henry Ford Health System, Detroit, Michigan, USA.

Background:: Femoral nerve block (FNB) is a commonly performed technique that has been proven to provide effective regional analgesia after anterior cruciate ligament (ACL) reconstruction. The adductor canal block (ACB) uses a similar sensory block around the knee while avoiding motor blockade of the quadriceps muscles.

Purpose/hypothesis:: The purpose of our study was to compare the efficacy of FNB versus ACB for pain control after ACL reconstruction. Read More

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December 2018

Insertion depth of nasotracheal tubes sized to fit the nostril: an observational study.

J Int Med Res 2018 Dec 16:300060518800105. Epub 2018 Dec 16.

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Yonsei-ro, Seodaemun-Gu, Seoul, Republic of Korea.

Objective: Nasotracheal (NT) intubation is commonly applied during head and neck surgery. However, improper tube size and depth may cause complications. In the current study, we investigated whether NT tubes are being appropriately used in terms of size and depth in adult patients. Read More

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December 2018

Aortic root changes before and after surgery for chronic aortic dilatation: A 3D Echocardiographic study.

Echocardiography 2018 Dec 16. Epub 2018 Dec 16.

Division of Cardiology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.

Background: Quantitative 3D assessment of the aortic root may improve planning and success of aortic valve (AV)-sparing operations.

Aims: To use 3D transesophageal echocardiography (TEE) to assess the effect of chronic aortic dilatation on aortic root shape and aortic regurgitation (AR) severity and to examine the effects of AV-sparing operations.

Methods And Results: To determine the changes with chronic aortic dilatation, we studied 48 patients, 23 with aortic dilatation (Group 1 ≤ mild AR, n = 13; Group 2 ≥ moderate AR, n = 10) and 25 Controls. Read More

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December 2018

Measuring depth of anaesthesia using changes in directional connectivity: a comparison with auditory middle latency response and estimated bispectral index during propofol anaesthesia.

Anaesthesia 2018 Dec 16. Epub 2018 Dec 16.

Institute of Sound and Vibration Research, University of Southampton, Southampton, UK.

General anaesthesia is associated with changes in connectivity between different regions of the brain, the assessment of which has the potential to provide a novel marker of anaesthetic effect. We propose an index that quantifies the strength and direction of information flow in electroencephalographic signals collected across the scalp, assess its performance in discriminating 'wakefulness' from 'anaesthesia', and compare it with estimated bispectral index and the auditory middle latency response. We used a step-wise slow induction of anaesthesia in 10 patients to assess graded changes in electroencephalographic directional connectivity at propofol effect-site concentrations of 2 μg. Read More

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December 2018

Short-term outcomes of outpatient surgery for total knee arthroplasty.

Singapore Med J 2018 Dec 17. Epub 2018 Dec 17.

Orthopaedics and Traumatology Department, Private Medicabil Hospital, Bursa, Turkey.

Introduction: We have developed an accelerated clinical pathway involving outpatient surgery for patients undergoing total knee arthroplasty (TKA) who are healthy enough for early discharge.

Methods: Between March 2014 and April 2015, 89 TKAs were performed at a single institution by a single orthopaedic surgeon. 31 patients met the inclusion criteria for the study. Read More

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December 2018

Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit.

Open Forum Infect Dis 2018 Dec 19;5(12):ofy313. Epub 2018 Nov 19.

Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium.

Background: There is a need to better define the epidemiology of sepsis in intensive care units (ICUs) around the globe.

Methods: The Intensive Care over Nations (ICON) audit prospectively collected data on all adult (>16 years) patients admitted to the ICU between May 8 and May 18, 2012, except those admitted for less than 24 hours for routine postoperative surveillance. Data were collected daily for a maximum of 28 days in the ICU, and patients were followed up for outcome data until death, hospital discharge, or for 60 days. Read More

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December 2018

Overexpression of USP5 contributes to tumorigenesis in non-small cell lung cancer via the stabilization of β-catenin protein.

Am J Cancer Res 2018 1;8(11):2284-2295. Epub 2018 Nov 1.

Department of Anesthesia, Jiaxing Maternity and Child Health Care Hospital, Jiaxing University Jiaxing 314001, Zhejiang, China.

The ubiquitin-specific protease 5 (USP5), a deubiquitinating enzyme, has been identified as a tumor promoter in several types of human cancer. However, the role of USP5 in non-small lung cancer (NSCLC) has not yet been elucidated. In this study, we found that USP5 was upregulated in NSCLC tissues compared with normal tissues. Read More

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November 2018

Longitudinal exploration of in situ mock code events and the performance of cardiac arrest skills.

BMJ Simul Technol Enhanc Learn 2019 Jan 2;5(1):29-33. Epub 2018 Mar 2.

Professor, Emeritus, UC Davis Department of Emergency Medicine.

Introduction: In hospital cardiac arrest (IHCA) affects 200,000 adults in the United States each year, and resuscitative efforts are often suboptimal. The objective of this study was to determine whether a program of "mock codes" improves group-level performance of IHCA skills. Our primary outcome of interest was change in CPR fraction, and the secondary outcomes of interest were time to first dose of epinephrine and time to first defibrillation. Read More

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January 2019

Management of malignant carinal involvement using 'side-by-side' method of bilateral self-expandable metallic stents.

Respirol Case Rep 2019 Feb 10;7(2):e00396. Epub 2018 Dec 10.

Department of Respiratory Medicine Uji-Tokushukai Medical Center Kyoto Japan.

Central airway obstruction caused by cancer requires urgent interventional pulmonology. Malignant main carinal involvement is one of the most challenging situations, usually treated by rigid bronchoscopic intervention under general anaesthesia. However, these patients tend to be in poor condition due to underlying malignancy. Read More

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February 2019

Primary repair of re-entry intimal tear in a patient with limited extension of acute type A aortic dissection.

J Surg Case Rep 2018 Dec 12;2018(12):rjy331. Epub 2018 Dec 12.

Division of Cardiac Surgery, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA.

Principles of type A aortic dissection surgery emphasize the importance of operative survival and long-term outcome. Various surgical strategies have emerged aiming for improved freedom of reoperation but they can be technically demanding or associated with higher operative risks. We report a type A aortic dissection case with extension of the dissection to the proximal descending aorta where a re-entry intimal tear was identified. Read More

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December 2018

Use of levosimendan in acute heart failure.

Eur Heart J Suppl 2018 Dec 11;20(Suppl I):I2-I10. Epub 2018 Dec 11.

Second Cardiology Department and Heart Failure Unit, Attikon Teaching Hospital, Athens, Greece.

As a calcium sensitizer and inodilator that augments cardiac contractility without increasing myocardial oxygen demand or exacerbating ischaemia, levosimendan may be well configured to deliver inotropic support in cases of acute heart failure (AHF). Other factors favouring levosimendan in this setting include its extended duration of action due to the formation of an active metabolite and the lack of any attenuation of effect in patients treated with beta-blockers. Effects of levosimendan on systemic haemodynamics include its significant, dose-dependent increases in cardiac output, stroke volume and heart rate, and decreases in right and left ventricular filling and total peripheral resistance. Read More

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December 2018

Oral and cutaneous myiasis in a five-year-old child from Karachi, Pakistan.

Infez Med 2018 Dec;26(4):385-388

Department of Oral and Maxillofacial Surgery, Dr. Ruth K.M Pfau Civil hospital, Karachi, Pakistan and Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.

Myiasis is a pathological condition in which there is a pestilence of fly larvae feeding on living or dead tissues. This disease is common in the tropics and subtropics of Africa and America and rarely affects humans. Our case report describes a five-year-old boy from Karachi, Pakistan with a history of extraction sockets and incisional biopsy of the left parotid lymph node. Read More

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December 2018
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Outcomes Among Patients With Heart Failure With Reduced Ejection Fraction Undergoing Transcatheter Aortic Valve Replacement: Minimally Invasive Strategy Versus Conventional Strategy.

J Invasive Cardiol 2018 Dec 15. Epub 2018 Dec 15.

University Hospitals Cleveland Medical Center, 11100 Euclid Ave, Mailstop LKS 5038, Cleveland, OH 44106 USA.

Objectives: To investigate the effect of TAVR technique on in-hospital and 30-day outcomes in patients with aortic stenosis (AS) and reduced ejection fraction (EF).

Background: Patients with AS and concomitant low EF may be at risk for adverse hemodynamic effects from general anesthesia utilized in transcatheter aortic valve replacement (TAVR) via the conventional strategy (CS). These patients may be better suited for the minimally invasive strategy (MIS), which employs conscious sedation. Read More

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December 2018

Is regional ankle block needed in conjunction with general anaesthesia for first ray surgery? A randomised controlled trial of ultrasound guided ankle block versus "blind" local infiltration.

Foot Ankle Surg 2018 Nov 28. Epub 2018 Nov 28.

Orthopaedic Surgery, Leicester General Hospital, University Hospitals of Leicester, Leicester, England, UK.

Background: Regional anaesthesia is commonly utilised for foot and ankle surgery. Debate remains at to the level of regional anaesthesia that is required. The objective of this study was to evaluate whether surgeon-delivered "blind" local anaesthetic infiltration around the first ray (metatarsal block without ultrasound guidance) was as effective as an ultrasound guided ankle block in providing post-operative analgesia after osseous first ray surgery performed under general anaesthetic. Read More

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November 2018

Liposomal Bupivacaine Versus Standard Periarticular Injection in Total Knee Arthroplasty With Regional Anesthesia: A Prospective Randomized Controlled Trial.

J Arthroplasty 2018 Nov 23. Epub 2018 Nov 23.

Department of Orthopedic Surgery, Grant Medical Center, OhioHealth, Columbus, OH.

Background: Liposomal bupivacaine (Exparel) is a long-acting local anesthetic preparation with demonstrated efficacy over placebo in reducing postoperative pain and opioid requirement. Limited comparative efficacy and cost-effectiveness data exist for its use in total knee arthroplasty (TKA) when used in a multimodal, opioid-sparing analgesic and anesthetic approach. We hypothesized that liposomal bupivacaine offers no clinical advantage over our standard of care but carries significant economic impact. Read More

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November 2018

Effect of meniscus repair on pivot-shift during anterior cruciate ligament reconstruction: Objective evaluation using triaxial accelerometer.

Knee 2018 Dec 13. Epub 2018 Dec 13.

Department of Joint Surgery and Sports Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan; Department of Orthopaedic Surgery, Tokyo Medical and Dental University Hospital of Medicine, Bunkyo-ku, Tokyo, Japan. Electronic address:

Background: Some types of meniscus tear, especially lateral meniscus tear, have been reported to be associated with rotatory knee laxity. However, precise information regarding the effect of meniscus repair on rotatory laxity is limited. The purpose of this study was to investigate the effects of lateral and medial meniscus repair on rotatory laxity in anterior cruciate ligament (ACL) injured knees. Read More

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December 2018

Effect of fentanyl on the induction dose and minimum infusion rate of alfaxalone preventing movement in dogs.

Vet Anaesth Analg 2018 Nov 14. Epub 2018 Nov 14.

Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, USA.

Objective: To determine the effect of fentanyl on the induction dose and minimum infusion rate of alfaxalone required to prevent movement in response to a noxious stimulus (MIR) in dogs.

Study Design: Experimental crossover design.

Animals: A group of six healthy, adult, intact female mixed-breed dogs, weighing 19. Read More

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November 2018

The Arabic translation, cultural adaptation, and validation of the pediatric voice-related quality of life survey.

Int J Pediatr Otorhinolaryngol 2019 Jan 13;116:30-33. Epub 2018 Oct 13.

Department of Pediatrics, King Khalid University Hospital, Riyadh, Saudi Arabia.

Objective: The aim of this study was to develop an Arabic version of the pediatric voice-related quality of life (PVRQOL) and test its validity and reliability.

Subjects: and methods: Fifty-one children with voice problems were included in the study along with 60 control children without any voice disorders. The translated Arabic PVRQOL and the Arabic pediatric voice handicap index (PVHI) have been distributed to the study subjects. Read More

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January 2019

Contemporary Management of Electrical Storm.

Heart Lung Circ 2019 Jan 15;28(1):123-133. Epub 2018 Oct 15.

Department of Cardiology, Westmead Hospital, Westmead Applied Research Centre, University of Sydney, Sydney, NSW, Australia. Electronic address:

Cardiac electrical storm (ES) is characterised by three or more discrete episodes of ventricular arrhythmia within 24hours, or incessant ventricular arrhythmia for more than 12hours. ES is a distinct medical emergency that portends a significant increase in mortality risk and often presages progressive heart failure. ES is also associated with psychological morbidity from multiple implanted cardioverter defibrillator (ICD) shocks and exponential health resource utilisation. Read More

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January 2019

Operative and Anesthetic Factors Influencing on Delirium in the Intensive Care Unit: An Analysis of Electronic Health Records.

J Clin Nurs 2018 Dec 16. Epub 2018 Dec 16.

College of Nursing, The Catholic University of Korea, Seoul, Republic of Korea.

Aims And Objectives: The purpose of this study was to analyze the operation, anesthesia, and recovery related factors affecting the occurrence of delirium in the intensive care unit.

Background: The occurrence rate of postoperative delirium is high in surgical patients. Postoperative delirium most frequently occurs usually within 3 days after an operation. Read More

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December 2018

TRs analysis revealed Staphylococcus epidermidis transmission among patients and hospital.

Ann Ig 2019 Jan-Feb;31(1):52-61

Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Background: As a great opportunistic pathogen, Staphylococcus epidermidis participates in a wide spectrum of infections by residing in the medical devices. Regardless of the clinical importance of S. epidermidis, there are a few data about typing of clinical and non-clinical isolates at the subspecies level in Iran. Read More

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December 2018

Use of supplemental oxygen in emergency patients: a systematic review and recommendations for military clinical practice.

J R Army Med Corps 2018 Dec 15. Epub 2018 Dec 15.

Emergency Department, University Hospitals Plymouth NHS Trust, Plymouth, UK.

Introduction: Supplemental oxygen is a key element of emergency treatment algorithms. However, in the operational environment, oxygen supply poses a challenge. The lack of high-quality evidence alongside emerging technologies provides the opportunity to challenge current guidelines. Read More

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December 2018

Combined erector spinae plane and interscalene brachial plexus block for surgical anesthesia of scapula fracture.

J Clin Anesth 2018 Dec 13;54:166-167. Epub 2018 Dec 13.

Department of Anesthesiology and Reanimation, Faculty of Meram Medicine, Necmettin Erbakan University, Konya, Turkey.

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December 2018

Standard and viscoelastic mechanical properties of respiratory system compartments in dogs: effect of volume, posture, and shape.

Respir Physiol Neurobiol 2018 Dec 13. Epub 2018 Dec 13.

Department of Physiopathology and Transplantations, Università degli Studi di Milano, Milan, Italy.

In 9 anesthetized, paralyzed dogs lung and chest-wall standard (viscous resistance, Rint, and quasi-static elastance, Est) and viscoelastic parameters (resistance, Rvel, and time constant, τvel) were measured in the supine posture before and after rib-cage block, after application of an expiratory threshold load, and after 75° head-up tilting before and after wide chest opening. Lung and chest-wall τvel were the same under all conditions. Rvel was independent of volume and posture, and greater for the lung. Read More

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December 2018

Inhibition of Protein Tyrosine Phosphatase 1B Protects Against Sevoflurane-induced Neurotoxicity mediated by ER stress in Developing Brain.

Brain Res Bull 2018 Dec 13. Epub 2018 Dec 13.

Department of Anesthesiology, Huashan Hospital, Fudan University, Shanghai, 200040, PR China. Electronic address:

Background: ER stress is involved in sevoflurane-induced neurotoxicity. Protein tyrosine phosphatase 1B (PTP1B) resided in the ER membrane is known to regulate ER stress. However, the role of PTP1B in sevoflurane-induced neurotoxicity is unknown. Read More

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December 2018

Risk factors for admission after shoulder arthroscopy.

J Shoulder Elbow Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Orthopaedic Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Background: Shoulder arthroscopy is a common orthopedic procedure typically performed on an outpatient basis. Occasionally, patients require an unplanned hospital admission. An understanding of the incidence and risk factors for admission after shoulder arthroscopy may assist surgeons in determining which patients may be susceptible to unplanned admission after surgery. Read More

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December 2018

Aspects of in vivo endotracheal tube intracuff pressure in cats.

Vet Anaesth Analg 2018 Oct 13. Epub 2018 Oct 13.

Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.

Objectives: To determine the endotracheal tube cuff pressure produced with two inflation techniques, in two brands of endotracheal tube in cats. To determine the inspiratory pressure which produces an audible leak when the intracuff pressure is 30 cmHO.

Study Design: Prospective, clinical, randomized study. Read More

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October 2018

Completely Percutaneous Transaxillary Aortic Valve Implantation Under Local Anesthesia: A Minimalist Alternative Access Approach.

JACC Cardiovasc Interv 2018 Dec 7. Epub 2018 Dec 7.

Department of Interventional Cardiology, Erasmus University Medical Center, Rotterdam, the Netherlands. Electronic address:

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December 2018

Anesthetic Considerations for Pediatric Patients With Congenital Long QT Syndrome.

J Cardiothorac Vasc Anesth 2018 Nov 12. Epub 2018 Nov 12.

Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Johns Hopkins All Children's Hospital, St. Petersburg, FL.

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November 2018

The lack of a magic bullet.

J Thorac Cardiovasc Surg 2018 Nov 8. Epub 2018 Nov 8.

Department of Minimally Invasive Cardiac Surgery, Cardiothoracic Center, Istituto Clinico Sant'Ambrogio, Milan, Italy. Electronic address:

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November 2018

Clinical Cybersecurity Training Through Novel High-Fidelity Simulations.

J Emerg Med 2018 Dec 12. Epub 2018 Dec 12.

Department of Anesthesia and Pain Medicine, University of California Davis, Davis, California.

Background: Cybersecurity risks in health care systems have traditionally been measured in data breaches of protected health information, but compromised medical devices and critical medical infrastructure present risks of disruptions to patient care. The ubiquitous prevalence of connected medical devices and systems may be associated with an increase in these risks.

Objective: This article details the development and execution of three novel high-fidelity clinical simulations designed to teach clinicians to recognize, treat, and prevent patient harm from vulnerable medical devices. Read More

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December 2018

Preoperative Low-dose and High-dose Pregabalin and Cardiovascular Response to Endotracheal Intubation: A Prospective, Randomized, Single-blind, Controlled Study in China.

Clin Ther 2018 Dec 12. Epub 2018 Dec 12.

Department of Anesthesiology, Qingpu Branch of Zhongshan Hospital affiliated with Fudan University, Shanghai, China.

Purpose: A prospective, randomized, single-blind, controlled clinical study was designed to evaluate the efficacy and tolerability of preoperative pregabalin on cardiovascular response to laryngoscopy and endotracheal intubation.

Methods: Patients aged 18-60 years with an American Society of Anesthesiologists scale score of I or II were recruited and randomly allocated to receive placebo (control), low-dose (150-mg) pregabalin, or high-dose (300-mg) pregabalin. The medications were orally administered 1 hour before general anesthesia. Read More

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December 2018

Sleep safe in clean hands: Improving hand hygiene compliance in the operating room through education and increased access to hand hygiene products.

Am J Infect Control 2018 Dec 12. Epub 2018 Dec 12.

Duke University School of Nursing, Durham, NC.

Background: Hand hygiene compliance is low among anesthesia providers in the operating room, which places patients at risk of preventable infections. The goal of this project was to improve hand hygiene compliance by educating anesthesia providers on the World Health Organization's 5 indications for hand hygiene, and increasing access to hand hygiene products in the operating room.

Methods: Observations of hand hygiene in the operating room took place in 3 phases: preimplementation, postimplementation, and 60 days postimplementation. Read More

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December 2018

Response to "individualized care in patients undergoing laparoscopic cholecystectomy".

Am J Surg 2018 Dec 10. Epub 2018 Dec 10.

Sainte Anne Military Hospital, Department of Oncologic and Digestive Surgery, Toulon, France; French Military Health Service Academy - Ecole du Val-de-Grâce, Paris, France.

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December 2018

Feasibility and clinical outcomes of ureteral stenting in the office procedural suite.

Can J Urol 2018 Dec;25(6):9596-9600

MD/PhD Program, Texas A & M Health Science Center College of Medicine, Temple, Texas, USA.

Introduction: Stent placement is a common procedure for addressing obstructive uropathy. However, lack of operating room (OR) availability can substantially delay this procedure. In this study, we sought to assess the feasibility, safety, and efficacy of this procedure in a clinical setting using nitrous oxide (N2O) and local anesthesia. Read More

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December 2018

ECMO circuit embolism: A potentially hazardous complication during ECMO therapy.

J Clin Anesth 2018 Dec 12;54:162-163. Epub 2018 Dec 12.

Department of Anesthesia, Teine Keijinkai Hospital, Sapporo, Japan.

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December 2018
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Synthesis and characterization of nanostructured lipid-poloxamer organogels for enhanced skin local anesthesia.

Eur J Pharm Sci 2018 Dec 12. Epub 2018 Dec 12.

Human and Natural Sciences Center, Federal University of ABC, Santo André, SP, Brazil. Electronic address:

The aim of this study was to synthesize a novel drug delivery system using organogels (ORGs) and characterize its physicochemical properties, in vitro and ex vivo permeation abilities, cytotoxicity and in vivo local anesthetic effects. The ORG formulations contained a mixture of oleic acid-lanolin (OA-LAN), poloxamer (PL407), and the commonly used local anesthetic lidocaine (LDC). The main focus was to evaluate the impact of LAN and PL407 concentrations on the ORG structural features and their biopharmaceutical performance. Read More

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December 2018
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The DAHANCA 32 study: Electrochemotherapy for recurrent mucosal head and neck cancer.

Head Neck 2018 Dec 15. Epub 2018 Dec 15.

Department of Otorhinolaryngology, Head & Neck Surgery and Audiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

Background: Electrochemotherapy is an established treatment for cutaneous tumors. This study aimed at determining efficacy of electrochemotherapy in recurrent head and neck cancer.

Methods: Phase II clinical trial in patients with recurrent head and neck carcinomas with no curative treatment options. Read More

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December 2018

EFFECT OF TIME OF THE DAY AND SPECIALITY ON POLYP DETECTION RATES IN AUSTRALIA.

J Gastroenterol Hepatol 2018 Dec 14. Epub 2018 Dec 14.

School of Medicine, the University of Adelaide, Adelaide, South Australia, Australia.

Background And Aim: Adenoma detection rate (ADR) is an important quality metric in colonoscopy. However, there is conflicting evidence around factors that influence ADR. This study aims to investigate the effect of time of day and endoscopist background on ADR and sessile serrated adenoma/polyp detection rate (SSA/P-DR) for screening colonoscopies. Read More

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December 2018
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Feasibility of transcatheter prosthetic paravalvular leakage closure: a single-center, exploratory safety evaluation study of transcatheter closure of prosthetic paravalvular regurgitation in Japan (STOP PARA study).

Gen Thorac Cardiovasc Surg 2018 Dec 14. Epub 2018 Dec 14.

Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Japan.

Objective: The standard treatment of prosthetic paravalvular leakage (PVL) accompanied by heart failure or hemolytic anemia is repeat open surgery. Although favorable outcomes for transcatheter prosthetic PVL closure in patients with a high surgical risk for repeat open surgery have been reported, procedural feasibility has not been examined in Japan.

Methods: From March 2015 to November 2015, transcatheter PVL closure in mitral position was performed in four patients (age range 41-78, three females) with high surgical risk due to history of repeated surgeries, chest radiation and reconstruction of the mitral annulus after debridement of abscess owing to infective endocarditis. Read More

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December 2018
2 Reads

Achieving proficiency in rigid bronchoscopy-a study in manikins.

Ir J Med Sci 2018 Dec 14. Epub 2018 Dec 14.

Department of Anaesthesia, The Rotunda Hospital, Parnell Square, Dublin, Ireland.

Background: Rigid bronchoscopy may be used to relieve acute airway obstruction following induction of anaesthesia and is a recommended option for management of the difficult airway. The ability of anaesthetists to perform rigid bronchoscopy has not been reported. We sought to explore the acquisition of procedural skill in rigid bronchoscopy by anaesthesiologists in a manikin. Read More

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December 2018

In Reply: Comment on "Encouraging a bare minimum while striving for the gold standard: a response to the updated WHO-WFSA guidelines".

Can J Anaesth 2018 Dec 14. Epub 2018 Dec 14.

Departments of Anesthesiology and Surgery, Division of Ambulatory Surgery, Vanderbilt Anesthesia Global Health& Development, Vanderbilt Institute for Global Health, Vanderbilt University School of Medicine and Vanderbilt University Medical Center, Nashville, TN, USA.

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December 2018