J Pharm Biomed Anal 2021 Nov 22;206:114388. Epub 2021 Sep 22.
Department of Biomedical, Metabolic and Neural Sciences, Unit of Medical Toxicology, Headache Centre and Drug Abuse, University of Modena and Reggio Emilia, via del Pozzo, 41124 Modena, Italy.
Migraine is a very painful, disabling and extremely common disorder among the world's adult population, especially women, and it is associated with a variety of comorbidities. Neuroactive steroids exhibit pleiotropic actions on the nervous system. Alterations in their peripheral and central levels could be involved in the pathogenesis, still not fully understood, of migraine and its comorbidities. Read More