3,180 results match your criteria Amphetamine-Related Psychiatric Disorders


Patterns and Characteristics of Methamphetamine Use Among Adults - United States, 2015-2018.

MMWR Morb Mortal Wkly Rep 2020 Mar 27;69(12):317-323. Epub 2020 Mar 27.

Methamphetamine is a highly addictive central nervous system stimulant. Methamphetamine use is associated with a range of health harms, including psychosis and other mental disorders, cardiovascular and renal dysfunction, infectious disease transmission, and overdose (1,2). Although overall population rates of methamphetamine use have remained relatively stable in recent years (3), methamphetamine availability and methamphetamine-related harms (e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15585/mmwr.mm6912a1DOI Listing

Effectiveness of Group Narrative Therapy on Depression, Quality of Life, and Anxiety in People with Amphetamine Addiction: A Randomized Clinical Trial.

Iran J Med Sci 2020 Mar;45(2):91-99

Department of Psychiatry, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Background: Drug abuse is a major issue and one of the main causes of health, psychological, and social problems. Studies have shown the effectiveness of narrative therapy in reducing psychological symptoms of addiction. The present study aimed to assess the effectiveness of group narrative therapy on depression, quality of life (QoL), and anxiety among people with amphetamine addiction in Kermanshah, Iran. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.30476/IJMS.2019.45829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071554PMC

Methamphetamine-induced Psychosis and Mental Impairment: A Challenge from New Zealand.

Authors:
Ian Freckelton

J Law Med 2019 Dec;27(2):284-293

While knowledge about chronic amphetamine-induced psychosis and its similarity to schizophrenia is at an early stage, its incidence and ramifications are posing a serious issue for the criminal law. The condition has the potential in principle to result in findings of insanity/mental impairment and diminished responsibility, as well as to be significantly mitigating at the time of sentencing. However, difficult legal questions arise as to whether an ongoing (as against transient) chronic methamphetamine-induced psychosis constitutes a "disease of the mind" as well as complex public policy issues by reason of the condition being self-induced. Read More

View Article

Download full-text PDF

Source
December 2019

Amphetamine dependence in Australia.

Authors:
Chris McCall

Lancet 2020 02;395(10221):325-326

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(20)30245-2DOI Listing
February 2020

Reducing negative consequences from use of methamphetamine.

Addiction 2020 06 27;115(6):1190-1191. Epub 2020 Jan 27.

National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/add.14966DOI Listing

Altered functional connectivity of the nucleus accumbens subdivisions in amphetamine-type stimulant abusers: a resting-state fMRI study.

BMC Neurosci 2019 12 30;20(1):66. Epub 2019 Dec 30.

The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Beijing, China.

Background: The growing abuse of amphetamine-type stimulants leads to new challenges to human health. A possible addiction mechanism has been proposed by altered functional architecture of the nucleus accumbens (NAc) during resting state. NAc contains different subdivisions and they may play different roles in addiction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12868-019-0548-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937793PMC
December 2019

Lithium Pharmacology and a Potential Role of Lithium on Methamphetamine Abuse and Dependence.

Curr Drug Res Rev 2019 ;11(2):85-91

Department of Pharmacology, Hyogo College of Medicine, Hyogo 663-8501, Japan.

Background: The effectiveness of lithium salts in neuropsychiatric disorders such as bipolar disorder, Alzheimer's disease, and treatment-resistant depression has been documented in an extensive scientific literature. Lithium inhibits inositol monophosphatase, inositol polyphosphate 1- phosphatase, and glycogen synthase kinase-3 and decreases expression level of tryptophan hydroxylase 2, conceivably underlying the mood stabilizing effects of lithium, as well as procognitive and neuroprotective effects. However, the exact molecular mechanisms of action of lithium on mood stabilizing and pro-cognitive effects in humans are still largely unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/2589977511666190620141824DOI Listing

Assessing the impacts of daily Cannabis versus alcohol and methamphetamines on young Australians in youth AOD treatment.

BMC Psychiatry 2019 12 23;19(1):416. Epub 2019 Dec 23.

Youth Support and Advocacy Service, Melbourne, Australia.

Background: Cannabis is the most widely used illicit substance by Australian young people, including those engaged with youth alcohol and other drug (AOD) systems. While recreational cannabis use in young people may be a developmental activity for some, for others, this usage becomes regular and be associated with poorer long term outcomes. This study reports on the rates of cannabis use and co-existing psychosocial complexity factors in the Youth Needs Census (2013 and 2016) where workers report on all clients in the youth AOD system, a cohort considered highly vulnerable. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12888-019-2403-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929317PMC
December 2019

Methamphetamine-induced alterations in intestinal mucosal barrier function occur via the microRNA-181c/ TNF-α/tight junction axis.

Toxicol Lett 2020 Mar 17;321:73-82. Epub 2019 Dec 17.

NHC Key Laboratory of Drug Addiction Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, 650032, Yunnan, China. Electronic address:

An enterogenic infection occurs when intestinal mucosal disruption is followed by the invasion of intestinal bacteria into the blood and distant organs, which can result in severe diseases or even death. Our previous study using Rhesus monkeys as an in vivo model revealed that methamphetamine (MA) induced intestinal mucosal barrier damage, which poses a high risk of enterogenic infection. However, how methamphetamine causes intestinal mucosal barrier damage remains largely unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.toxlet.2019.12.020DOI Listing

Randomized controlled trial of a positive affect intervention to reduce HIV viral load among sexual minority men who use methamphetamine.

J Int AIDS Soc 2019 12;22(12):e25436

Department of Medical Social Sciences, Northwestern University, Chicago, CA, USA.

Introduction: In the era of HIV treatment as prevention (TasP), evidence-based interventions that optimize viral suppression among people who use stimulants such as methamphetamine are needed to improve health outcomes and reduce onward transmission risk. We tested the efficacy of positive affect intervention delivered during community-based contingency management (CM) for reducing viral load in sexual minority men living with HIV who use methamphetamine.

Methods: Conducted in San Francisco, this Phase II randomized controlled trial tested the efficacy of a positive affect intervention for boosting and extending the effectiveness of community-based CM for stimulant abstinence to achieve more durable reductions in HIV viral load. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jia2.25436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924317PMC
December 2019

Development of Thiazolidinedione-Based HDAC6 Inhibitors to Overcome Methamphetamine Addiction.

Int J Mol Sci 2019 Dec 9;20(24). Epub 2019 Dec 9.

College of Pharmacy, Keimyung University, Daegu 42601, Korea.

Thiazolidinedione is a five-membered heterocycle that is widely used in drug discovery endeavors. In this study, we report the design, synthesis, and biological evaluation of a series of thiazolidinedione-based HDAC6 inhibitors. In particular, compound exerts an excellent inhibitory activity against HDAC6 with an IC value of 21 nM, displaying a good HDAC6 selectivity over HDAC1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20246213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940941PMC
December 2019

From opiates to methamphetamine: building new harm reduction responses in Jakarta, Indonesia.

Harm Reduct J 2019 12 11;16(1):67. Epub 2019 Dec 11.

University Center of Psychiatry, University Medical Center of Groningen, Groningen, Netherlands.

Background: Despite the rise of stimulant use, most harm reduction programs still focus on people who inject opioids, leaving many people who use methamphetamine (PWUM) underserviced. In Asia, especially, where methamphetamine prevalence has overtaken opioids prevalence, harm reduction programs assisting PWUM are rare. The few existing innovative practices focusing on methamphetamine use lie underreported. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12954-019-0341-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907268PMC
December 2019

Disrupted resting-state brain functional network in methamphetamine abusers: A brain source space study by EEG.

PLoS One 2019 11;14(12):e0226249. Epub 2019 Dec 11.

Department of Biomedical Engineering, University of Connecticut, Storrs, CT, United States of America.

This study aimed to examine the effects of chronic methamphetamine use on the topological organization of whole-brain functional connectivity network (FCN) by reconstruction of neural-activity time series at resting-state. The EEG of 36 individuals with methamphetamine use disorder (IWMUD) and 24 normal controls (NCs) were recorded, pre-processed and source-reconstructed using standardized low-resolution tomography (sLORETA). The brain FCNs of participants were constructed and between-group differences in network topological properties were investigated using graph theoretical analysis. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0226249PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906079PMC

Safer smoking kits for methamphetamine consumption.

Addiction 2020 06 24;115(6):1189-1190. Epub 2020 Jan 24.

Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/add.14914DOI Listing

Comparison of Clinical Characteristics and Outcomes of Patients With Reversible Versus Persistent Methamphetamine-Associated Cardiomyopathy.

Am J Cardiol 2020 01 11;125(1):127-134. Epub 2019 Oct 11.

Division of Cardiology, University of California, San Francisco, San Francisco, CA.

Anecdotal cases of reversible methamphetamine-associated cardiomyopathy (rMAC) have been reported, but not well understood. This study sought to determine the clinical characteristics, outcomes and predictors of reversibility among patients with rMAC as compared with patients with persistent MAC (pMAC). We retrospectively studied adult MAC patients with left ventricular ejection fraction (LVEF) ≤40% at a single center between 2004 and 2018. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjcard.2019.09.030DOI Listing
January 2020
3.276 Impact Factor

Time perception deficits and its dose-dependent effect in methamphetamine dependents with short-term abstinence.

Sci Adv 2019 10 30;5(10):eaax6916. Epub 2019 Oct 30.

Research Center of Brain and Cognitive Neuroscience, Liaoning Normal University, Dalian, Liaoning 116029, China.

Intake of addictive substances acutely modifies dopaminergic transmission in the striatum and prefrontal cortex, which is the neural substrate underlying time processing. However, the persistent effects of methamphetamine (meth) abuse (e.g. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/sciadv.aax6916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821467PMC
October 2019
1 Read

Pharmacotherapeutic strategies for methamphetamine use disorder: mind the subgroups.

Expert Opin Pharmacother 2019 Dec 31;20(18):2273-2293. Epub 2019 Oct 31.

Institute of Pharmacology and Experimental Therapeutics/iCBR, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.

: Drug use related deaths are increasing and the lack of effective treatment for psychostimulants can be largely held responsible. Particularly, no pharmacotherapy is approved for methamphetamine (METH) use disorder despite decades of research. Only psychosocial interventions are clinically used, with limited long-term recovery and relapse. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14656566.2019.1681970DOI Listing
December 2019

Nod-like receptor protein 3 and nod-like receptor protein 1 inflammasome activation in the hippocampal region of postmortem methamphetamine chronic user.

Bratisl Lek Listy 2019 ;120(10):769-776

Objective And Background: Methamphetamine (Meth) is one of the most important central nervous system (CNS) stimulant abuse drugs that cause long-term or permanent damage to different regions of the brain, particularly hippocampus, by neuronal apoptosis and inflammation. In this study, we evaluated Nod-like Receptor Protein 3(NLRP3) and Nod-like Receptor Protein1 (NLRP1) Inflammasome Activation in the Hippocampal Region of postmortem Meth Chronic User.

Methods: Molecular and histological analyses were conducted on the brain of 14 non-addicted and 11 Meth users separately. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4149/BLL_2019_129DOI Listing
November 2019

Methamphetamine withdrawal and the restoration of cognitive functions - a study over a course of 6 months abstinence.

Psychiatry Res 2019 11 3;281:112599. Epub 2019 Oct 3.

LMU Munich, Department of Psychiatry and Psychotherapy University Hospital, Nussbaumstraße 7, 80336 Munich, Germany. Electronic address:

A continuously rising consumption of methamphetamine (MA) has been suggested to be associated with increasing cognitive dysfunction. The objective of this study was to investigate associations between cognitive functions and gender, drug using patterns and treatment-attending profiles of recently abstinent MA users over the course of six months abstinence. Data were collected from 108 participants in two inpatient rehabilitation centers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.psychres.2019.112599DOI Listing
November 2019

Prevalence of self-reported movement dysfunction among young adults with a history of ecstasy and methamphetamine use.

Drug Alcohol Depend 2019 12 27;205:107595. Epub 2019 Sep 27.

School of Pharmacy and Medical Sciences, University of South Australia, GPO Box 2471, Adelaide, SA, 5001, Australia. Electronic address:

Background: Illicit stimulant use is associated with long-lasting changes in movement and movement-related brain regions. The aim of our study was to investigate the prevalence of movement dysfunction in this population. We hypothesized that prevalence of self-reported movement dysfunction is higher among stimulant users than non-stimulant users. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2019.107595DOI Listing
December 2019
1 Read

Trace amine-associated receptor gene polymorphism increases drug craving in individuals with methamphetamine dependence.

PLoS One 2019 10;14(10):e0220270. Epub 2019 Oct 10.

Research & Development Service, VA Portland Health Care System, Portland, OR, United States of America.

Background: Methamphetamine (MA) is a potent agonist at the trace amine-associated receptor 1 (TAAR1). This study evaluated a common variant (CV) in the human TAAR1 gene, synonymous single nucleotide polymorphism (SNP) V288V, to determine the involvement of TAAR1 in MA dependence.

Methods: Participants (n = 106) with active MA dependence (MA-ACT), in remission from MA dependence (MA-REM), with active polysubstance dependence, in remission from polysubstance dependence, and with no history of substance dependence completed neuropsychiatric symptom questionnaires and provided blood samples. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0220270PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786581PMC
March 2020
1 Read

Sex Differences in Escalated Methamphetamine Self-Administration and Altered Gene Expression Associated With Incubation of Methamphetamine Seeking.

Int J Neuropsychopharmacol 2019 11;22(11):710-723

Molecular Neuropsychiatry Research Branch, NIDA Intramural Research Program, Baltimore, MD.

Background: Methamphetamine (METH) use disorder is prevalent worldwide. There are reports of sex differences in quantities of drug used and relapses to drug use among individuals with METH use disorder. However, the molecular neurobiology of these potential sex differences remains unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ijnp/pyz050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902093PMC
November 2019
2 Reads

Nonmedical use of d-Amphetamines and Methylphenidate in Medical Students.

P R Health Sci J 2019 09;38(3):185-188

Associate Professor Department of Biochemistry and Pharmacology, San Juan Bautista School of Medicine, Caguas, PR.

Objective: The purpose of this study was to determine the prevalence of medical and nonmedical use of prescription attention deficit hyperactive disorder (ADHD) stimulant medication among medical students.

Materials And Methods: An IRB approved 19-question web survey was sent out to all students from a Puerto Rico (PR) medical school to assess use of ADHD medication. Out of the 250 stu-dents consulted there was a response of 152 surveys. Read More

View Article

Download full-text PDF

Source
September 2019
3 Reads

Antibody production and pharmacokinetics of METH in rats following vaccination with the METH vaccine, IXT-v100, adjuvanted with GLA-SE.

Drug Alcohol Depend 2019 11 30;204:107484. Epub 2019 Aug 30.

InterveXion Therapeutics, LLC, 4301 W. Markham St., #831, Little Rock, AR 72205, USA; Department of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, 4301 W. Markham St., #611, Little Rock, AR 72205, USA.

Background: Methamphetamine use disorder continues to be inadequately treated, but improvements are being made in the field of immunotherapeutics, including vaccines, which could provide new options for treatment. Cocaine and nicotine vaccines have been tested clinically, but have yet to elicit the necessary antibody concentrations required to be effective. Methamphetamine vaccines have been tested in multiple nonclinical models and appear promising. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2019.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878175PMC
November 2019

Neurotoxische und vaskulopathische ZNS-Veränderungen im Rahmen eines chronischen Metamphetamin-Abusus.

Rofo 2019 Oct 11;191(10):942-943. Epub 2019 Sep 11.

Neuroradiologie, HELIOS-Klinikum Berlin-Buch, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/a-0881-3315DOI Listing
October 2019

Methamphetamine Use: A New Wave in the Opioid Crisis?

Authors:
Susanne A Fogger

J Addict Nurs 2019 Jul/Sep;30(3):219-223

Susanne A. Fogger, DNP, PMHNP-BC, CARN-AP, FAANP, School of Nursing, University of Alabama at Birmingham.

Background: The ongoing drug crisis in the United States continues to be headlined with numbers of deaths related to opioid overdose. Less known to the public and health care providers is the rise in methamphetamine use, often in conjunction with opioids or adulterated with fentanyl. An old practice with a new twist is the use of methamphetamine in conjunction with an opioid such as heroin. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/JAN.0000000000000298DOI Listing
February 2020
2 Reads

Long-Acting Injectable Aripiprazole for a Schizophrenic Patient Concomitant With Stimulant Use Disorder.

J Clin Psychopharmacol 2019 Sep/Oct;39(5):508-509

Center of Medical GeneticsHualien Tzu Chi HospitalBuddhist Tzu Chi Medical FoundationHualien, Taiwan. Department of PsychiatryHualien Tzu Chi HospitalBuddhist Tzu Chi Medical Foundation and School of MedicineTzu Chi UniversityHualien,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/JCP.0000000000001087DOI Listing

Crystal methamphetamine's impact on frontline emergency services in Victoria, Australia.

Australas Emerg Care 2019 Dec 17;22(4):201-205. Epub 2019 Aug 17.

School of Health, University of New England, Armidale, NSW 2351 Australia.

Background: The use of crystal methamphetamine is a growing problem in Australia. Methamphetamine users can suffer adverse physical health effects, psychotic symptoms and methamphetamine-related aggressive behaviour. The increasing use and related harms of crystal methamphetamine is presenting serious problems for frontline emergency responders. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.auec.2019.07.004DOI Listing
December 2019

Amphetamine exposure and dementia - A hypothesis of the long term sequelae of cognitive enhancers based on opponent process theory.

Med Hypotheses 2019 Nov 25;132:109327. Epub 2019 Jul 25.

Department of Psychiatry, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei City, Taiwan; Department of Psychiatry, Cheng Hsin General Hospital, Taipei City, Taiwan; Laboratory of Cognitive Neuroscience, Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan. Electronic address:

Dementia is a cluster of brain dysfunctions with a characteristic of progressively debilitating in individuals' ability of operating cognitive functions and that affects seriously to patients' daily life. We presented a hypothesis in this article that earlier exposure of a common used cognitive enhancer amphetamine may lead to individuals to be more liable to develop dementia in their later life based on the opponent process theory. The theory proposes that following a positive response, homeostatic changes in brain circuits may function to go opposite to the positive response, thus a cognitive deterioration may incur in later life in the individuals who exposed to amphetamine earlier. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mehy.2019.109327DOI Listing
November 2019
1 Read

Prenatal methamphetamine exposure: Overinterpretations in South Africa.

Compr Psychiatry 2019 11 31;95:152111. Epub 2019 Jul 31.

Columbia University in the City of New York, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.comppsych.2019.07.004DOI Listing
November 2019
1 Read

Amphetamines signal through intracellular TAAR1 receptors coupled to Gα and Gα in discrete subcellular domains.

Mol Psychiatry 2019 Aug 9. Epub 2019 Aug 9.

National Institute of Mental Health, National Institutes of Health, Bethesda, MD, 20892, USA.

The extensive use of amphetamines to treat attention deficit hyperactivity disorders in children provides a compelling rationale for understanding the mechanisms of action of amphetamines and amphetamine-related drugs. We have previously shown that acute amphetamine (AMPH) regulates the trafficking of both dopamine and glutamate transporters in dopamine neurons by increasing activation of the small GTPase RhoA and of protein kinase A. Here we demonstrate that these downstream signaling events depend upon the direct activation of a trace amine-associated receptor, TAAR1, an intracellular G-protein coupled receptor (GPCR) that can be activated by amphetamines, trace amines, and biogenic amine metabolites. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41380-019-0469-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038576PMC
August 2019
2 Reads

Associations between methamphetamine use, psychiatric comorbidities and treatment outcome in two inpatient rehabilitation centers.

Psychiatry Res 2019 10 1;280:112505. Epub 2019 Aug 1.

Department of Psychiatry and Psychotherapy University Hospital Munich, LMU Munich, Nussbaumstraße 7, Munich 80336, Germany.

The use of methamphetamine is spreading globally and provokes the need for effective treatment options. Previous research showed increased psychiatric comorbidities in methamphetamine users, but its impact on treatment success is still unclear. This study investigates data from two German addiction rehabilitation centers including 108 methamphetamine using individuals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.psychres.2019.112505DOI Listing
October 2019
2 Reads

The Impact of Substance Abuse on Heart Failure Hospitalizations.

Am J Med 2020 02 29;133(2):207-213.e1. Epub 2019 Jul 29.

Division of Cardiovascular Medicine, Department of Medicine, University of California, San Diego. Electronic address:

Background: The burden of substance abuse among patients with heart failure and its association with subsequent emergency department visits and hospital admissions are poorly characterized.

Methods: We evaluated the medical records of patients with a diagnosis of heart failure treated at the University of California-San Diego from 2005 to 2016. We identified substance abuse via diagnosis codes or urine drug screens. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjmed.2019.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980459PMC
February 2020
2 Reads

A randomized clinical trial on the effects of bupropion and buprenorphine on the reduction of methamphetamine craving.

Trials 2019 Jul 30;20(1):468. Epub 2019 Jul 30.

Substance Abuse Research Center, Shiraz University of Medical Sciences, Chamran BLVD, Hafez Hospital, Shiraz, Iran.

Background: The purpose of this study was to compare the effect of 300 mg of bupropion and 8 mg of buprenorphine per day on the treatment of methamphetamine withdrawal cravings over a 2-week treatment interval.

Method: Sixty-five methamphetamine-dependent men who met the DSM-IV-TR (Diagnostic and Statistical Manual of Mental Disorders, 4th edition, text revision) criteria for methamphetamine dependence and withdrawal were randomly divided into two groups. Subjects randomly received 300 mg of bupropion or 8 mg of buprenorphine per day in a psychiatric ward. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13063-019-3554-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668115PMC
July 2019
2 Reads

Characterizing Men Who Have Sex with Men and Use Injection Drugs in Vancouver, Canada.

AIDS Behav 2019 Dec;23(12):3324-3330

School of Public Policy, Simon Fraser University, Vancouver, BC, Canada.

We examined factors associated with reporting sex with men among men who inject drugs in Vancouver, Canada. Data were drawn from three open prospective cohorts of people who use drugs between 2005 and 2014. Generalized estimating equations were used to identify factors associated with reporting non-transactional sex with men (MSM) in the previous 6 months. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10461-019-02605-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032567PMC
December 2019
1 Read

Cannabidiol Treatment Might Promote Resilience to Cocaine and Methamphetamine Use Disorders: A Review of Possible Mechanisms.

Molecules 2019 Jul 16;24(14). Epub 2019 Jul 16.

Unit of Research "Neurobehavioural mechanisms and endophenotypes of addictive behavior", Department of Psychobiology, University of Valencia, Avda. Blasco Ibañez 21, 46010 Valencia, Spain.

Currently, there are no approved pharmacotherapies for addiction to cocaine and other psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a promising treatment for substance use disorders. In the present work, the authors describe the scarce preclinical and human research about the actions of CBD on the effects of stimulant drugs, mainly cocaine and methamphetamine (METH). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules24142583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680550PMC
July 2019
2 Reads

Psychoactive drug consumption among truck-drivers: a systematic review of the literature with meta-analysis and meta-regression.

J Prev Med Hyg 2019 Jun 28;60(2):E124-E139. Epub 2019 Jun 28.

Department of Health Sciences (DISSAL), Occupational Medicine, University of Genoa, Italy.

Few studies have assessed the extent of psychoactive drug consumption in the occupational setting. The trucking sector, in particular, is an important cause for concern, since psychoactive substance use has a relevant impact on the drivers' health and safety, increasing the risk of injuries and traffic accidents, potentially affecting the general public health as well. A systematic review of the literature and meta-analysis was performed in order to provide Occupational Health Professionals and policy-makers with an updated epidemiological perspective regarding this important issue. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15167/2421-4248/jpmh2019.60.2.1245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614564PMC
June 2019
1 Read

[Imaging changes in brain microstructural in long-term abstinent from methamphetamine-dependence].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2019 May;44(5):491-500

Department of Radiology, Second Xiangya Hospital, Central South University, Changsha 410011, China.

Objective: To explore the mechanism for changes in brain microstructure in long-term abstinent from methamphetamine-dependence by using the diffusion tensor imaging (DTI).
 Methods: A total of 26 patients with long-term abstinent methamphetamine-dependence, whose abstinence time more than 14 months, and 26 normal controls all underwent cognitive executive function tests and DTI scans. We used voxel-based analysis to compare the fractional anisotropy (FA) and mean diffusivity (MD) to obtain the abnormal brain regions of DTI parameters between the two groups. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11817/j.issn.1672-7347.2019.05.004DOI Listing
May 2019
7 Reads

Is there a discrete negative symptom syndrome in people who use methamphetamine?

Compr Psychiatry 2019 08 28;93:27-32. Epub 2019 Jun 28.

National Drug Research Institute, Curtin University, GPO Box 1987, Perth, WA 6845, Australia; National Drug and Alcohol Research Centre, University of New South Wales, 22-32 King Street, Randwick, NSW 2031, Australia. Electronic address:

Background: Positive psychotic symptoms have consistently been associated with methamphetamine use but the presence of a negative symptom cluster remains unclear. We used exploratory factor analysis to examine whether a discrete negative syndrome could be delineated among methamphetamine users, and to examine the clinical correlates of this syndrome.

Method: Participants (N = 154) were people who used methamphetamine at least monthly and did not meet DSM-IV diagnostic criteria for lifetime schizophrenia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.comppsych.2019.06.002DOI Listing
August 2019
9 Reads

Increasing use of stimulants in Australia: Cause for health services concern.

Int J Ment Health Nurs 2019 Aug;28(4):795-797

School of Health, University of New England, Armidale, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/inm.12636DOI Listing
August 2019
1 Read

Methamphetamine use in an early psychosis service: a cross-sectional retrospective cohort study.

Australas Psychiatry 2019 Aug 2;27(4):383-387. Epub 2019 Jul 2.

Early Intervention in Psychosis Service, Sydney Local Health District, Camperdown, NSW, Australia.

Objective: Methamphetamine-associated psychotic symptoms are common among regular users, and can overlap with the emergence of a primary psychotic disorder. In contrast to previous research, this retrospective observational study aims to describe the characteristics of young people experiencing early psychosis who use methamphetamine regularly. We also aimed to investigate associations between regular methamphetamine use and markers of psychosocial functioning, psychosis outcomes and substance use. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1039856219859811DOI Listing
August 2019
2 Reads

[Metamphetamine-related disorders: Diagnostics and therapy].

Fortschr Neurol Psychiatr 2019 Jun 1;87(6):385-398. Epub 2019 Jul 1.

In recent years, mental and behavioral disorders caused by methamphetamine - crystal meth - have increased sharply in Germany. This mainly affects federal states near the border with the Czech Republic. But also nationally, the importance of the drug is increasing, especially in chemsex scenes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0044-100786DOI Listing
June 2019
10 Reads

Perceived factors influencing the initiation of methamphetamine use among Akha and Lahu youths: a qualitative approach.

BMC Public Health 2019 Jun 28;19(1):847. Epub 2019 Jun 28.

School of Health Science, Mae Fah Luang University, Chiang Rai, Thailand.

Background: Methamphetamine use not only impacts health and the economy but also causes social impairment, particularly among the poorly educated and underprivileged young populations among the hill tribes in northern Thailand. Youths are the most vulnerable population for methamphetamine use due to various factors, including parenting styles, childhood exposure, and location of the village. This qualitative approach aimed to investigate the perceived factors influencing the initiation of methamphetamine use among the Akha and Lahu youths in northern Thailand. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12889-019-7226-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599247PMC
June 2019
3 Reads

Who's that SMARTgirl? Reaching Cambodian Female Entertainment and Sex Workers with HIV Prevention Services.

AIDS Behav 2020 Mar;24(3):738-745

Division of Prevention Science and Community Health, Department of Public Health Sciences, University of Miami, 1120 NW 14th St., Office 1005, Miami, FL, 33136, USA.

Engagement in prevention services is crucial to reducing HIV risk among female entertainment and sex workers (FESW), and SMARTgirl is the national social marketing HIV prevention program for Cambodian women engaged in sex and entertainment work. Informed by the Behavioral Model of Vulnerable Populations, three multivariate logistic regression analyses examined correlates of three indices of engagement along the SMARTgirl HIV prevention continuum: (1) receipt of outreach services (past 3 months); (2) being registered as a SMARTgirl member; and (3) SMARTgirl club attendance (past year). Among the 1077 FESW enrolled in nine Cambodian provinces, women working in a brothel or freelance (adjusted odds ratio [aOR] 2. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10461-019-02532-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925653PMC
March 2020
23 Reads

Treatment of amphetamine abuse/use disorder: a systematic review of a recent health concern.

Daru 2019 Dec 21;27(2):743-753. Epub 2019 Jun 21.

Women's and New Born Health Department, Westmead Hospital, Sydney, Australia.

Objectives: The study systematically reviewed the effectiveness of pharmacological treatments alone or combined with brief cognitive-behavioural therapy (BCBT) for treating Iranian amphetamine abusers. The secondary aim was to review the efficacy of BCBT alone or combined with pharmacological treatments for treating amphetamine abusers in the world.

Evidence Acquisition: Published trials were considered for inclusion. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40199-019-00282-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895313PMC
December 2019
18 Reads

Comparison of the mental health status of methamphetamine-dependent inmates and drug-addiction rehabilitation program participants in Japan.

Psychiatry Clin Neurosci 2019 Sep 2;73(9):596. Epub 2019 Jul 2.

Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pcn.12903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851568PMC
September 2019
17 Reads

Oxytocin treatment in the prelimbic cortex reduces relapse to methamphetamine-seeking and is associated with reduced activity in the rostral nucleus accumbens core.

Pharmacol Biochem Behav 2019 08 13;183:64-71. Epub 2019 Jun 13.

Macquarie University, Department of Psychology, North Ryde, 2109, Australia.

Addiction to the psychostimulant Methamphetamine (METH) is characterised by high rates of relapse. Currently there are no approved effective pharmacotherapies for METH dependence. The neuropeptide oxytocin (OXY) potently reduces METH-seeking behaviours in rodent models of relapse and is now being used in clinical trials to treat drug-dependent individuals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pbb.2019.06.002DOI Listing
August 2019
1 Read

Comment on Zang et al 2019: The importance of distinguishing between psychotic and general psychiatric symptoms in the context of methamphetamine use.

Addict Biol 2020 03 13;25(2):e12776. Epub 2019 Jun 13.

National Drug Research Institute (NDRI), Curtin University, Perth, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/adb.12776DOI Listing
March 2020
2 Reads

Patterns and features of methamphetamine-related presentations to emergency departments in QLD from 2005 to 2017.

Int J Ment Health Nurs 2019 Aug 9;28(4):833-844. Epub 2019 Jun 9.

School of Health, University of New England, Armidale, New South Wales, Australia.

This study explores the patterns and features of methamphetamine-related presentations to emergency departments (EDs) in Queensland. Despite an overall decrease in the use of methamphetamine in Australian, an increase in the use of the crystalized form of methamphetamine has been noted over recent years. A descriptive observational study was utilized to analyse emergency department (ED) injury surveillance data sourced from Queensland Injury Surveillance Unit (QISU) from 2005 to 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/inm.12618DOI Listing
August 2019
12 Reads

Regional differences in white matter integrity in stimulant use disorders: A meta-analysis of diffusion tensor imaging studies.

Drug Alcohol Depend 2019 08 29;201:29-37. Epub 2019 May 29.

Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, 1941 East Rd., Houston, TX, 77054, USA.

Background: Converging lines of evidence from diffusion tensor imaging (DTI) studies reveal significant alterations in white matter (WM) microstructure in the prefrontal cortex of chronic stimulant users compared to controls, suggesting compromised axonal microstructure and/or myelin.

Methods: A meta-analysis of DTI-based WM integrity was conducted for white matter regions across the corpus callosum and association fibers. Articles were sourced and selected using PRISMA guidelines for systematic review and meta-analysis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drugalcdep.2019.03.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660908PMC
August 2019
12 Reads
3.423 Impact Factor