2,817 results match your criteria American journal of therapeutics[Journal]


Metabolic Monitoring of Child and Adolescent Patients on Atypical Antipsychotics by Psychiatrists and Primary Care Providers.

Am J Ther 2019 Feb 7. Epub 2019 Feb 7.

Department of Psychiatry, McLeod Medical Center, Florence, SC.

Background: Antipsychotic drug use in children has doubled from 2001 to 2007 with concomitant increase in obesity. Second-generation antipsychotic (SGA) medication use is associated with weight gain, metabolic derangements, and blood sugar and lipid abnormalities in children. The American Psychiatric Association and the American Diabetes Association have recommended metabolic monitoring guidelines for patients using SGA. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000853DOI Listing
February 2019

Clozapine Might Relieve Rhinotillexomania and Related Epistaxis in Schizophrenia Patients: A Case Report.

Am J Ther 2019 Jan 30. Epub 2019 Jan 30.

Department of Psychiatry, Beitou Branch, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

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http://dx.doi.org/10.1097/MJT.0000000000000943DOI Listing
January 2019
2 Reads

Manganese Toxicity Complicating Parenteral Nutrition.

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Am J Ther 2019 Jan 30. Epub 2019 Jan 30.

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http://dx.doi.org/10.1097/MJT.0000000000000899DOI Listing
January 2019
1 Read

Lisdexamfetamine Overdose.

Am J Ther 2019 Jan 29. Epub 2019 Jan 29.

Department of Emergency Medicine, Wellspan Health, York Hospital, York, PA.

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http://dx.doi.org/10.1097/MJT.0000000000000941DOI Listing
January 2019

Amphotericin B-Induced Hyperbilirubinemia.

Am J Ther 2019 Jan 29. Epub 2019 Jan 29.

Saint Vincent Medical Center Frank H. Netter School of Medicine Quinnipiac University Bridgeport, CT.

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http://dx.doi.org/10.1097/MJT.0000000000000939DOI Listing
January 2019

Use of Direct Oral Anticoagulants in the Treatment of Left Ventricular Thrombus: Systematic Review of Current Literature.

Am J Ther 2019 Jan 29. Epub 2019 Jan 29.

Department of Cardiology, Detroit Medical Center, John D. Dingell VA Medical Center, Wayne State University School of Medicine, Detroit, MI.

Background: Left ventricular thrombus (LVT) is an important complication in the setting of systolic dysfunction, particularly after acute myocardial infarction. Current guidelines recommend the vitamin-K antagonist, warfarin, for the treatment of LVT.

Area Of Uncertainty And Study Question: The direct oral anticoagulants (DOACs) are being increasingly used for the management of this entity, despite lack of randomized trials in support of it or knowledge about their efficacy. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000937DOI Listing
January 2019
1 Read

Aripiprazole Induced Late Neuroleptic Malignant Syndrome.

Am J Ther 2019 Feb 1. Epub 2019 Feb 1.

Department of Internal Medicine, Saint Vincent Medical Center/Quinnipiac University Frank H. Netter School of Medicine, Bridgeport, CT.

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http://dx.doi.org/10.1097/MJT.0000000000000944DOI Listing
February 2019
1 Read

Effect of a 30-Month Health-Promoting Program on the Prevalence of Cardiovascular Risk Factors in Patients With First Episode Schizophrenia.

Am J Ther 2019 Jan 18. Epub 2019 Jan 18.

Department of Psychiatry, University of Southern Denmark, Vejle, Denmark.

Background: Lifestyle interventions aimed at reducing cardiovascular risk factors in patients with first-episode schizophrenia (FES) have shown modest efficacy, probably owing to a short observation period and the presumption of linear trajectories of cardiovascular risk factors.

Study Question: How prevalent are abnormal cardiovascular values in patients with FES and how do cardiovascular risk factors develop during a 30-month program?

Study Design: A 30-month naturalistic longitudinal study of 136 consecutively referred patients with FES from 2 outpatient clinics. The health-promoting program consisted of individual guidance, group sessions, and normal treatment and care. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000708DOI Listing
January 2019

Albuterol-Induced Lactic Acidosis.

Am J Ther 2019 Jan 16. Epub 2019 Jan 16.

Department of Medicine, SUNY Upstate Medical University, Syracuse, NY.

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http://dx.doi.org/10.1097/MJT.0000000000000843DOI Listing
January 2019
2 Reads

Efficacy of Sacubitril/Valsartan in Hypertension.

Am J Ther 2019 Jan 10. Epub 2019 Jan 10.

Background: Sacubitril/valsartan (LCZ696) has progressed to be one of the most promising medication since its approval for chronic heart failure with reduced ejection fraction. Recent data have suggested a superior blood pressure control with LCZ696.

Study Question: What is the antihypertensive efficacy and safety profile of sacubitril/valsartan?

Data Sources: Randomized controlled trials (RCTs) comparing the efficacy and safety of LCZ696 against a placebo or angiotensin receptor blocker (ARB). Read More

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http://dx.doi.org/10.1097/MJT.0000000000000925DOI Listing
January 2019
2 Reads

Efficacy of Intranasal Insulin in Improving Cognition in Mild Cognitive Impairment and Alzheimer Disease: A Systematic Review and Meta-analysis.

Authors:
Jian Lu Zhongye Xu

Am J Ther 2019 Jan 3. Epub 2019 Jan 3.

Department of Neurosurgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

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http://dx.doi.org/10.1097/MJT.0000000000000926DOI Listing
January 2019
2 Reads

Acute Autoimmune Leukoencephalopathy Secondary to Adalimumab Therapy.

Authors:
Parthvi Rukma

Am J Ther 2019 Jan 3. Epub 2019 Jan 3.

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http://dx.doi.org/10.1097/MJT.0000000000000911DOI Listing
January 2019
1 Read

Glucagon for Refractory Anaphylaxis.

Authors:
Parthvi Rukma

Am J Ther 2019 Jan 3. Epub 2019 Jan 3.

Department of Pulmonary, Critical care and Sleep Medicine, University at Buffalo, The State University of New York, Buffalo, NY.

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http://dx.doi.org/10.1097/MJT.0000000000000910DOI Listing
January 2019
2 Reads

Elevations in High-Sensitive Cardiac Troponin T and N-Terminal Prohormone Brain Natriuretic Peptide Levels in the Serum Can Predict the Development of Anthracycline-Induced Cardiomyopathy.

Am J Ther 2019 Jan 3. Epub 2019 Jan 3.

Neurology, Clinical Research, UC Irvine School of Medicine, Irvine, CA.

Background: Anthracyclines remain the cornerstone of the treatment in many cancers including lymphomas, leukemia and sarcomas, and breast cancer. The cardiomyopathy that develops from anthracyclines can lead to heart failure and decreased survival. Multiple mechanisms are involved in the pathophysiology of anthracycline-induced heart failure. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000930DOI Listing
January 2019
2 Reads

Comparative Therapeutic Assessment of Atrial Fibrillation in Heart Failure With Reduced Ejection Fraction-A Network Meta-Analysis.

Am J Ther 2018 Dec 17. Epub 2018 Dec 17.

Background: Catheter ablation (CA) continues to prove to be an intriguing therapeutic option for the management of atrial fibrillation (AF) especially in patients with heart failure with reduced ejection fraction (HFrEF). Recent data have suggested that CA may be a viable first-line strategy for these patients.

Study Question: Is CA more effective in managing patients with AF with HFrEF compared to optimal medical treatment and anti-arrhythmic drugs?

Data Sources: Randomized controlled trials (RCTs) comparing CA, medical treatment, or antiarrhythmic drugs to each other or a placebo group for the treatment of AF in HFrEF. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000892DOI Listing
December 2018
10 Reads

A Rare Case of Fulvestrant-Associated Jaundice and Hepatotoxicity.

Am J Ther 2019 Jan/Feb;26(1):e122-e123

Department of Medicine, State University of New York (SUNY) Upstate Medical University, Syracuse, NY.

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http://dx.doi.org/10.1097/MJT.0000000000000532DOI Listing
January 2019
1 Read

Fidaxomicin and Fecal Microbiota Transplants for Severe Clostridium difficile Colitis.

Am J Ther 2019 Jan/Feb;26(1):e115-e117

Division of Gastroenterology, Department of Medicine, Mount Sinai St. Luke's and Mount Sinai West Hospitals, Icahn School of Medicine, New York, NY.

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http://dx.doi.org/10.1097/MJT.0000000000000573DOI Listing
January 2019
2 Reads

Polycaprolactone Antimony Nanoparticles as Drug Delivery System for Leishmaniasis.

Am J Ther 2019 Jan/Feb;26(1):e12-e17

Laboratory of Radiopharmacy and Nanoradiopharmaceuticals, Zona Oeste State University, Rio de Janeiro, Brazil.

Background: Leishmaniasis is a neglected disease endemic in tropical and subtropical areas, with an incidence about 1.6 million cases/year. The first-line treatment of this disease is pentavalent antimony, and the second-line are pentamidine and amphotericin B. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000539DOI Listing
January 2019
3 Reads

Laryngeal Edema Caused by Phloroglucinol: Erratum.

Authors:

Am J Ther 2019 Jan/Feb;26(1):e182

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http://dx.doi.org/10.1097/MJT.0000000000000935DOI Listing
January 2019
1 Read

Lamotrigine Uses in Psychiatric Practice.

Am J Ther 2019 Jan/Feb;26(1):e96-e102

Emergency Psychiatry Department, Kuwait Centre for Mental Health (KCMH), Shuwaikh, Kuwait.

Background: Lamotrigine (LAM), an antiepileptic, with panoply of indications and uses in neurology, is FDA approved, in psychiatry, for bipolar prophylaxis. Apart from this indication, trend of its use in psychiatry is on the rise addressing a multitude of disorders.

Study Question: LAM remains one of only few psychotropic drugs with antiglutamate activity. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000535DOI Listing
January 2019
5 Reads
1.127 Impact Factor

Tetracycline Re-exposure-Induced Toxic Epidermal Necrolysis.

Am J Ther 2018 Dec 19. Epub 2018 Dec 19.

Department of Internal Medicine, St. Joseph Mercy Oakland Hospital, Pontiac, MI.

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http://dx.doi.org/10.1097/MJT.0000000000000904DOI Listing
December 2018
5 Reads

Apatinib as Salvage Treatment in BRCA2-Mutated Advanced Lung Adenocarcinoma.

Am J Ther 2018 Dec 20. Epub 2018 Dec 20.

Department of Respiratory and Critical Care, First Affiliated Hospital of Soochow University, Suzhou, China.

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http://dx.doi.org/10.1097/MJT.0000000000000905DOI Listing
December 2018
1 Read

A New Safety Scoring System for the Use of Psychotropic Drugs During Lactation.

Authors:
Faruk Uguz

Am J Ther 2018 Dec 26. Epub 2018 Dec 26.

Background: Psychotropic drugs are frequently used to treat postpartum women with psychiatric diagnoses, especially psychotic disorder, major depression, and bipolar mood episodes. Pharmacotherapy in breastfeeding mothers is a major challenge.

Study Question: This article presents a new safety scoring system for the use of psychotropic drugs during lactation. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000909DOI Listing
December 2018
3 Reads

Mirtazapine for Inappropriate Sexual Behaviors in Autism.

Am J Ther 2018 Dec 26. Epub 2018 Dec 26.

General Adult Psychiatric Departments, Kuwait Centre for Mental Health, Kuwait.

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http://dx.doi.org/10.1097/MJT.0000000000000908DOI Listing
December 2018
4 Reads
1.127 Impact Factor

Eribulin-Associated Foot Drop.

Am J Ther 2018 Dec 17. Epub 2018 Dec 17.

East Carolina University Brody School of Medicine, Greenville, NC.

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http://dx.doi.org/10.1097/MJT.0000000000000881DOI Listing
December 2018
1 Read

Labetalol or Amphetamine: A Case of Mistaken Identity With Clinical Consequence.

Am J Ther 2018 Dec 11. Epub 2018 Dec 11.

Division of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY.

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http://dx.doi.org/10.1097/MJT.0000000000000901DOI Listing
December 2018
6 Reads

Hyperglycemic ADR Distribution of Doxorubicin From VigiBase.

Am J Ther 2018 Dec 14. Epub 2018 Dec 14.

Department of Pharmacy, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1097/MJT.0000000000000900DOI Listing
December 2018
2 Reads

Methylphenidate-Induced Yawning Chasm in an Adolescent With Attention-Deficit/Hyperactivity Disorder That Resolved by Switching to Atomoxetine.

Am J Ther 2018 Dec 7. Epub 2018 Dec 7.

Al-Manara CAP Centre, KCMH, Kuwait and Tufts University, Medford.

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http://dx.doi.org/10.1097/MJT.0000000000000896DOI Listing
December 2018
6 Reads
1.127 Impact Factor

Clinical Therapeutic Effects of Hypofractionated and Conventional Fractionated Radiotherapies on Non-small Cell-Lung Cancer.

Am J Ther 2019 Jan 18. Epub 2019 Jan 18.

Department of Radiotherapy, Second People's Hospital of Huaian, Huaian, P. R. China.

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http://dx.doi.org/10.1097/MJT.0000000000000621DOI Listing
January 2019
9 Reads
1.127 Impact Factor

Comparative Effectiveness and Safety of Rivaroxaban in Adults With Nonvalvular Atrial Fibrillation.

Am J Ther 2018 Nov 19. Epub 2018 Nov 19.

Quality Assurance, Evidence-Based Medicine Center, Philadelphia, PA.

Background: All evidence regarding benefits and harms of rivaroxaban for stroke prevention has not been appraised yet.

Study Question: What are the comparative effectiveness and safety of rivaroxaban in adults with nonvalvular atrial fibrillation?

Data Sources: Randomized controlled trials (RCTs), meta-analyses, and observational studies were identified in several databases in October 2018.

Study Design: Rapid review with evidence appraisal using the Grading of Recommendations Assessment, Development and Evaluation working group approach. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000890DOI Listing
November 2018
11 Reads

Typical Versus Atypical Antipsychotics for Acute Mania.

Am J Ther 2018 Nov 8. Epub 2018 Nov 8.

Department of Affective Disorders Q, Aarhus University Hospital, Risskov, Denmark.

Background: Mania is challenging to treat. Typical antipsychotics may be more efficient compared with atypical antipsychotics, however, with unfavorable side effects.

Study Question: To investigate the courses of acute manic episodes and correlations between changes of severity during manic episodes and type of antipsychotic treatment. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000871DOI Listing
November 2018
7 Reads

Step-wise Drug Therapy for Comorbid Bipolar and Obsessive-Compulsive Disorders.

Am J Ther 2018 Oct 23. Epub 2018 Oct 23.

General Adult Psychiatry, Kuwait Centre for Mental Health, Kuwait.

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http://dx.doi.org/10.1097/MJT.0000000000000872DOI Listing
October 2018
5 Reads
1.127 Impact Factor

Preventive Effect of L-Carnitine on Scar Formation During Acute Pyelonephritis: A Randomized Placebo-Controlled Trial.

Am J Ther 2018 Oct 24. Epub 2018 Oct 24.

Department of Physiology, Applied Physiology Research, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Urinary tract infection and pyelonephritis are clinical problems that frequently occur in children. Several factors are responsible for renal tissue injury, morbidity, and renal scarring after pyelonephritis. The aim of this study was to evaluate the preventive effect of L-carnitine on renal scarring in acute pyelonephritis. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000875DOI Listing
October 2018
13 Reads

Correlation of Cardiovascular Risk Factors and Biomarkers With Platelet Reactivity in Coronary Artery Disease.

Am J Ther 2018 Oct 29. Epub 2018 Oct 29.

Department of Medical and Surgical Specialties, Faculty of Medicine, "Transilvania" University, Brasov, Romania.

Background: Low response to aspirin, aspirin resistance, and high platelet reactivity on aspirin treatment are similar names for lack of response to block arachidonic acid-induced aggregation with aspirin therapy and have an important role in the evolution of coronary artery disease (CAD) with thromboembolic events.

Study Question: Was to evaluate the correlation between cardiovascular risk factors, biomarkers, and low response to aspirin in patients (pts) with CAD.

Study Design: Four hundred pts with CAD were divided into 8 groups of study, consistent with the type of CAD and low response to aspirin. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000869DOI Listing
October 2018
8 Reads

Combination of Quetiapine Immediate Release and XR for H1-Antihistamine-Refractory Chronic Spontaneous Urticaria Comorbid With Depressive Disorder: A Case Report.

Am J Ther 2018 Nov 1. Epub 2018 Nov 1.

Department of Psychiatry, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

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http://Insights.ovid.com/crossref?an=00045391-900000000-9853
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http://dx.doi.org/10.1097/MJT.0000000000000877DOI Listing
November 2018
7 Reads

Flurbiprofen-Associated Hemolytic Anemia.

Am J Ther 2018 Nov 1. Epub 2018 Nov 1.

Department of Emergency Medicine, Adana City Training and Research Hospital, Adana, Turkey.

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http://dx.doi.org/10.1097/MJT.0000000000000879DOI Listing
November 2018
2 Reads

Symptomatic Bradycardia on Propafenone After Discontinuation of Amiodarone.

Am J Ther 2018 Nov 8. Epub 2018 Nov 8.

Departments of Internal and Cardiovascular Medicine, St. Joseph Mercy Oakland Hospital, Pontiac, MI.

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http://dx.doi.org/10.1097/MJT.0000000000000885DOI Listing
November 2018
1 Read

Effect of β-Lactam Plus Macrolide Versus Fluoroquinolone on 30-Day Readmissions for Community-Acquired Pneumonia.

Am J Ther 2018 May 22. Epub 2018 May 22.

Pharmacy, Mayo Clinic Health System, Franciscan Healthcare in La Crosse, La Crosse, WI.

Background: Antibiotic therapy with a macrolide and β-lactam or a fluoroquinolone for the empirical treatment of community-acquired pneumonia (CAP) in an inpatient non-intensive care setting is recommended per guidelines. Studies show that these treatments have similar outcomes, including death, adverse effects, and bacterial eradication. However, a comparison of 30-day readmission rates between these treatments is limited. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000788DOI Listing
May 2018
6 Reads

Discontinuation of Long-Term Proton Pump Inhibitor Therapy.

Authors:
Pramod Reddy

Am J Ther 2018 Nov 8. Epub 2018 Nov 8.

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http://dx.doi.org/10.1097/MJT.0000000000000887DOI Listing
November 2018
1 Read

Dabigatran-Associated Thrombocytopenia.

Am J Ther 2018 Nov/Dec;25(6):e701-e704

Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA.

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http://dx.doi.org/10.1097/MJT.0000000000000714DOI Listing
November 2018
1 Read

Enoxaparin-Induced Massive Abdominal Wall Hematoma Presenting in Hypovolemic Shock.

Am J Ther 2018 Nov/Dec;25(6):e682-e683

Pulmonary Medicine, East Tennessee State University, Johnson City, TN.

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http://dx.doi.org/10.1097/MJT.0000000000000629DOI Listing
November 2018
1 Read

Case of Erythema Multiforme Drug Eruption Induced by Ledipasvir/Sofosbuvir: Erratum.

Authors:

Am J Ther 2018 Nov/Dec;25(6):e784

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http://dx.doi.org/10.1097/MJT.0000000000000876DOI Listing
November 2018
1 Read

Iatrogenic Takotsubo Cardiomyopathy.

Am J Ther 2018 Nov/Dec;25(6):e695-e698

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of Toledo, Toledo, OH.

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http://dx.doi.org/10.1097/MJT.0000000000000707DOI Listing
November 2018
1 Read

Outcomes of Noninvasive Ventilation in Obese Patients With Acute Asthma Exacerbations.

Am J Ther 2018 Nov/Dec;25(6):e635-e641

Division of In-patient medicine, Department of Medicine, Banner University Medical Center, Phoenix, AZ.

Background: The role of noninvasive positive pressure ventilation (NIPPV) in acute asthma exacerbation is controversial. However, the outcome of NIPPV in obese patients with asthma during such exacerbation has not been well studied despite well-established relationship between obesity and asthma.

Study Question: Does body mass index (BMI) play a role in the outcome of NIPPV during an acute exacerbation and does it predict of the success or failure of NIPPV?

Study Design: The study was a retrospective analysis by design. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000864DOI Listing
November 2018
12 Reads

Clozapine-Associated Myocarditis: Is It Time to Start Monitoring?

Am J Ther 2018 Oct 8. Epub 2018 Oct 8.

Division of Cardiology, Department of Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY.

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http://dx.doi.org/10.1097/MJT.0000000000000866DOI Listing
October 2018
3 Reads