3,093 results match your criteria American journal of therapeutics[Journal]


Opioid Crises-the Perspective From a Developing Country.

Am J Ther 2020 Jul/Aug;27(4):e422-e424

1Medical and Surgical Department, Faculty of Medicine, Transilvania University of Brasov, Brasov, Romania 2Hospice Casa Sperantei, Education and National Development Department Brasov, Romania 3Basic, Preventive and Clinical Sciences Department.

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http://dx.doi.org/10.1097/MJT.0000000000001184DOI Listing

Implementation of a Weight-Based Protocol for the Management of Steroid-Induced Hyperglycemia.

Am J Ther 2020 Jul/Aug;27(4):e392-e399

1Department of Internal Medicine, Division of Endocrinology, North Shore University Hospital, Manhasset, NY; 2Donald and Barbara Zucker School of Medicine at Northwell, Hempstead, NY; 3Feinstein Institute for Medical Research, Northwell Health, Manhasset, NY; 4Department of Internal Medicine, North Shore University Hospital, Manhasset, NY; 5Department of Pharmacy, North Shore University Hospital, Manhasset, NY; and 6Department of Pharmacy, St. John's University, Jamaica, NY.

Background: Hyperglycemia is a recognized complication of supraphysiological steroid dosing. There are no consensus guidelines on optimal treatment of steroid-induced hyperglycemia. We assessed the safety of a weight-based insulin protocol for persons treated with supraphysiological doses of steroids to examine the efficacy of using this protocol in patients with diabetes treated with prednisone or methylprednisolone. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000998DOI Listing

Self-Medicating for Pain: A Public Health Perspective.

Am J Ther 2020 Jul/Aug;27(4):e387-e391

Basic, Preventive and Clinical Sciences Department, Transilvania University of Brasov, Faculty of Medicine, Brasov, Romania.

Background: Pain is one of the symptoms for which any man is willing not only to go to the doctor but also to resort to any means, including self-medication, to "get rid" of it. Self-medication is not only a current practice but also a public health problem, under the circumstances that it can influence the way in which a disease is diagnosed and/or treated in a timely manner, and, consequently, repercussions may occur on the cost of treatment, in the case of severe forms. Pain is a vital symptom, and the diminution until the disappearance of pain is a fundamental right of each individual; the analysis of ethical issues in the case of self-administration of analgesic medication has not been a major concern. Read More

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http://dx.doi.org/10.1097/MJT.0000000000001173DOI Listing

Teriparatide for the Treatment of Medication-Related Osteonecrosis of the Jaw.

Am J Ther 2020 Jun 22. Epub 2020 Jun 22.

Department of Dentistry, Sri Aurobindo Institute of Medical Sciences, Indore, India.

Medication-related osteonecrosis of the jaw (MRONJ) is a painful and intractable disease of the jaw that clinically presents as an area of ulceration with exposed necrotic bone. In severe cases, it can predispose to jaw fracture, skin fistula, or osteolysis extending beyond the region of the alveolar bone. No effective treatment has been established for this condition. Read More

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http://dx.doi.org/10.1097/MJT.0000000000001182DOI Listing

Antipsychotics in Postpartum Psychosis.

Am J Ther 2020 Jun 22. Epub 2020 Jun 22.

Faculty of Medicine, Transilvania University of Brasov, Brasov, Romania.

Background: Psychotic episodes in the postpartum period are life-threatening psychiatric emergencies, requiring urgent medical attention and admission to a psychiatric hospital.

Areas Of Uncertainty: Although the postpartum psychosis (PPP) is the most severe psychiatric disorder associated with parturition, there is little information about what interventions are most effective. Because there are no specific guidelines for the treatment of PPP, the aim of the present review was to examine the available evidence regarding the treatment of PPP. Read More

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http://dx.doi.org/10.1097/MJT.0000000000001218DOI Listing

Foscarnet-Associated Nephrogenic Diabetes Insipidus.

Am J Ther 2020 Jun 12. Epub 2020 Jun 12.

Department of Nephrology, Detroit Medical Center, Wayne State University, Detroit, MI.

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http://dx.doi.org/10.1097/MJT.0000000000001211DOI Listing

Sunitinib as Successful Maintenance Therapy for Recurrent Pancreatic Serous Cystadenocarcinoma.

Am J Ther 2020 Jun 9. Epub 2020 Jun 9.

Northwell Health Cancer Institute, Lake Success, NY.

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http://dx.doi.org/10.1097/MJT.0000000000001205DOI Listing
June 2020
1.127 Impact Factor

Prolonged Coagulopathy With Dabigatran Despite Multiple Doses of Idarucizumab: A Case of Incomplete Reversal.

Am J Ther 2020 Jun 9. Epub 2020 Jun 9.

Pharmacy Department, ProMedica Toledo Hospital; Toledo, OH.

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http://dx.doi.org/10.1097/MJT.0000000000001209DOI Listing

Knowledge and Clinical Uptake of HIV Pre-exposure Prophylaxis by Internal Medicine Residents at a Teaching Hospital in the Southern United States.

Am J Ther 2020 Jun 8. Epub 2020 Jun 8.

Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX.

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http://dx.doi.org/10.1097/MJT.0000000000001125DOI Listing

Interstitial Pneumonitis-A Newly Recognized Consequence of Intravesical Gemcitabine Therapy.

Am J Ther 2020 Jun 2. Epub 2020 Jun 2.

Department of Pulmonary Medicine, Rochester General Hospital, Rochester, NY.

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http://dx.doi.org/10.1097/MJT.0000000000001206DOI Listing

Maintenance of Stable Disease in Metastatic Perivascular Epithelioid Cell Tumor of the Liver With Single-Agent Sorafenib.

Am J Ther 2020 Jun 2. Epub 2020 Jun 2.

Division of Medical Oncology, University of Kansas Medical Center, Kansas City, KS.

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http://dx.doi.org/10.1097/MJT.0000000000001207DOI Listing

Gabapentin-Induced Liver Toxicity.

Am J Ther 2020 Jun 5. Epub 2020 Jun 5.

Internal Medicine, SUNY Upstate Medical University, Syracuse, NY.

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http://dx.doi.org/10.1097/MJT.0000000000001208DOI Listing

Abemaciclib-Associated Status Epilepticus.

Authors:
Fazal I Raziq

Am J Ther 2020 Jun 1. Epub 2020 Jun 1.

Michigan State University, King Edward Medical University, Lansing, MI.

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http://dx.doi.org/10.1097/MJT.0000000000001179DOI Listing

Bevacizumab and Pancreatitis; an Uncommon Association.

Am J Ther 2020 Jun 1. Epub 2020 Jun 1.

Division of Pulmonary and Critical Care Medicine, SUNY Upstate Medical University, Syracuse, NY.

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http://dx.doi.org/10.1097/MJT.0000000000001199DOI Listing
June 2020
1.127 Impact Factor

Corticosteroid-Flared Hepatotoxicity Reversed With L-Carnitine Therapy in a Patient Treated With Long-Term Valproic Acid.

Am J Ther 2020 Jun 1. Epub 2020 Jun 1.

Department of Infectious Diseases, Goztepe Training and Research Hospital, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.

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http://dx.doi.org/10.1097/MJT.0000000000001171DOI Listing

Anti-Xa Activity-Guided Edoxaban Therapy for Cancer-Associated Venous Thromboembolism?

Am J Ther 2020 Jun 1. Epub 2020 Jun 1.

Department of Internal Medicine I, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovak Republic.

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http://dx.doi.org/10.1097/MJT.0000000000001202DOI Listing

Can Acitretin Be Effective Alone in the Treatment of Crusted Scabies?

Am J Ther 2020 May 26. Epub 2020 May 26.

Department of Dermatology and Venereology, the Republic of Turkey, Health Sciences University Erzurum Regional Training and Research Hospital, Erzurum, Turkey.

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http://dx.doi.org/10.1097/MJT.0000000000001163DOI Listing

Punding Related to Methylphenidate-Aripiprazole Combination in a Hyperkinetic Low-Functioning Autism Spectrum Disorder Child.

Am J Ther 2020 May 26. Epub 2020 May 26.

Head of Al-Manara CAP Centre, KCMH, Shuwaikh, Kuwait.

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http://dx.doi.org/10.1097/MJT.0000000000001201DOI Listing
May 2020
1.127 Impact Factor

Durvalumab-Associated Granulomatous Reaction Mimicking Recurrence of Lung Cancer.

Am J Ther 2020 May 26. Epub 2020 May 26.

Department of Pathology, Mayo Clinic Health System, Eau Claire, WI.

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http://dx.doi.org/10.1097/MJT.0000000000001204DOI Listing

How to Reduce Cardiovascular Risk in Nonalcoholic Fatty Liver Disease.

Am J Ther 2020 May 26. Epub 2020 May 26.

Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Background: Nonalcoholic fatty liver disease (NAFLD) is a rapidly growing multisystem disease with extrahepatic manifestations, including effects on the cardiovascular (CV) system. The leading cause of death in NAFLD is of cardiac etiology being ischemic heart disease.

Areas Of Uncertainty: NAFLD is associated with several CV complications including cardiac structural and functional alterations. Read More

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http://dx.doi.org/10.1097/MJT.0000000000001174DOI Listing

Kava Kava Induced Acute Liver Failure.

Authors:
Fazal I Raziq

Am J Ther 2020 May 25. Epub 2020 May 25.

Michigan State University, King Edward Medical University, Lansing, MI.

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http://dx.doi.org/10.1097/MJT.0000000000001180DOI Listing

Comparison of Single-Dose and Extended-Duration Empiric Aminoglycoside Combination Therapy in Patients With Septic Shock.

Am J Ther 2020 Jan 16. Epub 2020 Jan 16.

Background: Empiric combination antimicrobial therapy is often used in patients with decompensating septic shock. However, the optimal duration of combination therapy is unknown.

Study Question: The goal of this study was to compare the clinical effects of a single dose of an aminoglycoside to an extended duration of aminoglycosides for combination therapy in patients with septic shock without renal dysfunction. Read More

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http://dx.doi.org/10.1097/MJT.0000000000001136DOI Listing
January 2020

Meningoencephalitis in a Patient Treated With Immune Checkpoint Inhibitors.

Am J Ther 2020 Feb 11. Epub 2020 Feb 11.

Department of Infectious Diseases, SUNY Upstate Medical University, Syracuse, NY.

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http://dx.doi.org/10.1097/MJT.0000000000001151DOI Listing
February 2020

Comparison of Antiplatelet Effects and Clinical Outcomes Between Ticagrelor Versus Clopidogrel in Chinese Patients With Acute Coronary Syndrome.

Am J Ther 2020 May 12. Epub 2020 May 12.

Department of Cardiology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

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http://dx.doi.org/10.1097/MJT.0000000000001190DOI Listing

Complete Response to Temozolomide in Metastatic Melanoma After Failure of 5 Lines of Treatment.

Am J Ther 2020 May 14. Epub 2020 May 14.

Hematology and Oncology, University of Cincinnati, Cincinnati, OH.

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http://dx.doi.org/10.1097/MJT.0000000000001186DOI Listing

Hydralazine-Associated Antineutrophil Cytoplasmic Antibodies-Vasculitis Restricted to the Lungs.

Am J Ther 2020 Apr 23. Epub 2020 Apr 23.

Department of Internal Medicine, Rochester General Hospital, Rochester, NY.

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http://dx.doi.org/10.1097/MJT.0000000000001185DOI Listing

Paliperidone-Associated Acute Oculogyric Crisis.

Am J Ther 2020 May 2. Epub 2020 May 2.

Forensic Psychiatry Unit, Bakirkoy Prof. Mazhar Osman Training and Research Hospital for Psychiatry, Neurology, and Neurosurgery, Istanbul, Turkey.

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http://dx.doi.org/10.1097/MJT.0000000000001183DOI Listing

Efficacy and Safety of Omalizumab for Chronic Spontaneous Urticaria: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Am J Ther 2020 May 14. Epub 2020 May 14.

Department of Dermatology, Beijing Chao-Yang Hospital, Beijing, China.

Background: Omalizumab has been proposed as a possible effective treatment of chronic spontaneous urticaria (CSU).

Study Question: We aimed to access the efficacy and safety of omalizumab in the treatment of CSU based on qualified, randomized controlled trials (RCTs).

Data Sources: PubMed, the Cochrane library, and Embase databases. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000912DOI Listing

Kratom-Associated Ventricular Fibrillation.

Am J Ther 2020 May 14. Epub 2020 May 14.

Beaumont Hospital, Dearborn, MI.

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http://dx.doi.org/10.1097/MJT.0000000000001134DOI Listing

Valproic Acid in the Treatment of Secondary Mania Caused by Metastatic Brain Tumors.

Am J Ther 2020 Jul/Aug;27(4):e405-e406

Department of Psychiatry Tri-Service General Hospital School of Medicine National Defense Medical Center Taipei, Taiwan, Republic of China.

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http://dx.doi.org/10.1097/MJT.0000000000000948DOI Listing

Early Lipid Emulsion Treatment of Central Nervous System Symptoms Induced by Ropivacaine Toxicity: A Case Report.

Am J Ther 2020 May 6. Epub 2020 May 6.

Institute of Health Sciences, Gyeongsang National University, Jinju-si, Gyeongsangnam-do, Republic of Korea.

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http://dx.doi.org/10.1097/MJT.0000000000001198DOI Listing
May 2020
1.127 Impact Factor

Sodium-Glucose Cotransporter-2 Inhibitors and the Risk of Amputation: What Is Currently Known?

Am J Ther 2020 May 6. Epub 2020 May 6.

Clinical and Administrative Pharmacy Department, The University of Georgia College of Pharmacy, Athens, GA.

Background: Diabetes mellitus is a major cause of morbidity and mortality in the United States. Twelve medication classes on the market reduce serum glucose including sodium-glucose cotransporter-2 (SGLT2) inhibitors. Potential benefits of these agents include improved glycemic control, weight loss, reduction in blood pressure, and possible reduction in cardiovascular events in patients with elevated cardiovascular risk. Read More

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http://dx.doi.org/10.1097/MJT.0000000000001164DOI Listing

Lithium-Induced Ekbom Syndrome in a Case of Juvenile Bipolar Mood Disorder.

Am J Ther 2020 May 6. Epub 2020 May 6.

Psychiatric Departments, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.

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http://dx.doi.org/10.1097/MJT.0000000000001187DOI Listing
May 2020
1.127 Impact Factor

Efficacy of Upfront Docetaxel With Androgen Deprivation Therapy for Castration-Sensitive Metastatic Prostate Cancer Among Minority Patients.

Am J Ther 2020 May 5. Epub 2020 May 5.

Department of Urology, University of Washington School of Medicine, Seattle, WA.

Background: Upfront docetaxel (UD) with androgen deprivation therapy (ADT) has been demonstrated to improve survival outcomes in metastatic castration-sensitive prostate cancer (mCSPC). However, existing studies have included predominantly Caucasian patients.

Study Question: To compare the efficacy of addition of UD to ADT in mCSPC to ADT alone among minority patients. Read More

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http://dx.doi.org/10.1097/MJT.0000000000001085DOI Listing

Severe Polyantihypertensive Drug Poisoning: Unresponsive to Conventional Therapies Treated by Plasmapheresis.

Am J Ther 2020 May 5. Epub 2020 May 5.

Department of Emergency Medicine, Adana City Training and Research Hospital, Adana, Turkey.

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http://dx.doi.org/10.1097/MJT.0000000000001148DOI Listing

Left Ventricular Systolic Dysfunction due to Hydroxychloroquine Toxicity.

Am J Ther 2020 May 5. Epub 2020 May 5.

Cardiology Department, Yeditepe University School of Medicine, Istanbul, Turkey.

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http://dx.doi.org/10.1097/MJT.0000000000001194DOI Listing

Sertraline-Induced Neutropenia and Fatigue in a Patient With End-Stage Renal Disease.

Am J Ther 2020 May 5. Epub 2020 May 5.

Department of Psychiatry, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.

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http://dx.doi.org/10.1097/MJT.0000000000001192DOI Listing

Fluoxetine-Induced "Rabbit Syndrome" in a Child With Juvenile Obsessive-Compulsive Disorder.

Am J Ther 2020 May 5. Epub 2020 May 5.

Head of Al-Manara CAP Centre, KCMH, Shuwaikh, Kuwait.

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http://dx.doi.org/10.1097/MJT.0000000000001195DOI Listing
May 2020
1.127 Impact Factor

Prolonged Viral RNA Shedding Duration in COVID-19.

Am J Ther 2020 Jun 1. Epub 2020 Jun 1.

Department of Pulmonary and Critical Care Medicine, First Affiliated Hospital of Soochow University, Suzhou, China.

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http://dx.doi.org/10.1097/MJT.0000000000001200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219830PMC

An Unusual Case of Hydrogen Peroxide-Induced Injury Presenting With Gas Gangrene.

Am J Ther 2020 May 1. Epub 2020 May 1.

Division of Internal Medicine, Rutgers Robert Wood Johnson Medical School, Saint Peter's University Hospital, New Brunswick, NJ.

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http://dx.doi.org/10.1097/MJT.0000000000001197DOI Listing

COVID-19 and Avoiding Ibuprofen. How Good Is the Evidence?

Am J Ther 2020 Jul/Aug;27(4):e400-e402

Department of Internal Medicine, Banner University Medical Center, University of Arizona, Tucson, AZ.

Ibuprofen is an over-the-counter medication that is used widely for the treatment of pain and fever during COVID-19 pandemic. A concern was raised regarding the safety of ibuprofen use because of its role in increasing ACE2 levels within the Renin-Angiotensin-Aldosterone system. ACE2 is the coreceptor for the entry of SARS-CoV-2 into cells, and so, a potential increased risk of contracting COVID-19 disease and/or worsening of COVID-19 infection was feared with ibuprofen use. Read More

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http://dx.doi.org/10.1097/MJT.0000000000001196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242088PMC

Low-Dosage Apatinib as Rescuing Treatment in Advanced Malignant Pleural Mesothelioma.

Am J Ther 2020 May/Jun;27(3):e326-e327

Department of Pulmonary and Critical Care Medicine, First Affiliated Hospital of Soochow University, Suzhou, China.

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http://dx.doi.org/10.1097/MJT.0000000000000992DOI Listing

Immune-Mediated Colitis due to Concurrent Ipilimumab and Nivolumab Therapy Treated With Infliximab.

Am J Ther 2020 Jul/Aug;27(4):e415-e417

Division of Gastroenterology & Hepatology, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.

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http://dx.doi.org/10.1097/MJT.0000000000001165DOI Listing

Fentanyl-Induced Thrombocytopenia.

Authors:
Daniel Rosas

Am J Ther 2020 Jun 1. Epub 2020 Jun 1.

Universidad CES, Medellín, Antioquia, COLOMBIA.

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http://dx.doi.org/10.1097/MJT.0000000000001167DOI Listing