368,408 results match your criteria American journal of speech-language pathology / American Speech-Language-Hearing Association[Journal]


Prenatal maternal stress and child hair cortisol Four years later: Evidence from a low-income sample.

Psychoneuroendocrinology 2020 May 17;117:104707. Epub 2020 May 17.

University of California, Los Angeles, United States. Electronic address:

Background: Maternal stress during pregnancy can influence the trajectory of fetal development, shaping offspring physiology and health in enduring ways. Some research implicates fetal programming of the hypothalamic-pituitary-adrenocortical (HPA) axis as a mediator of these effects. The present study is the first to examine child hair cortisol concentration (HCC) and maternal stress during pregnancy in a diverse, low-income sample. Read More

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http://dx.doi.org/10.1016/j.psyneuen.2020.104707DOI Listing

Non-Arsenical heartworm adulticidal therapy using topical moxidectin-imidacloprid and doxycycline: A prospective case series.

Vet Parasitol 2020 May 11;282:109099. Epub 2020 May 11.

North Carolina State University College of Veterinary Medicine, 1052 William Moore Dr, Raleigh, NC, 27606, United States.

This prospective case series evaluated the adulticidal efficacy of topical 10 % moxidectin/2.5 % imidacloprid (M/I; Advantage Multi®, Bayer, Shawnee Mission, KS, USA) and doxycycline in dogs with naturally occurring heartworm infection (HWI). Twenty-two dogs with HWI whose owners declined melarsomine were treated with M/I at the preventive dosage twice monthly for 90 days then monthly thereafter and doxycycline (median [interquartile range; IQR] dosage 12. Read More

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http://dx.doi.org/10.1016/j.vetpar.2020.109099DOI Listing

Safety First: Developing and Deploying a System to Promote Safety and Quality in Your Clinic.

Pract Radiat Oncol 2020 May 22. Epub 2020 May 22.

University of Washington, Department of Radiation Oncology, Seattle WA.

The terms "safety and quality" (SAQ) have become inextricably linked, highly utilized terms that together encompass a wide range of parameters within medical departments. Safety has always been a priority in radiation oncology; quality assurance has been foundational to our practice. Despite this increased focus and attention on SAQ, the "what" of SAQ remains ill-defined, largely because of the vast number of indicators that fall under this umbrella. Read More

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http://dx.doi.org/10.1016/j.prro.2020.05.002DOI Listing

National Analysis of Perioperative Morbidity of Vaginal Versus Laparoscopic Hysterectomy at the Time of Uterosacral Ligament Suspension.

J Minim Invasive Gynecol 2020 May 22. Epub 2020 May 22.

Case Western Reserve University School of Medicine, Cleveland, OH.; MetroHealth Medical Center, Cleveland, OH.

Study Objective: The objective of this study was to compare the morbidity of vaginal versus laparoscopic hysterectomy when performed with uterosacral ligament suspension (USLS).

Design: Retrospective propensity-matched cohort study.

Setting: American College of Surgeons National Surgical Quality Improvement Program database. Read More

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http://dx.doi.org/10.1016/j.jmig.2020.05.015DOI Listing

Influence of Bleeding Risk on Outcomes of Radial and Femoral Access for Percutaneous Coronary Intervention: An Analysis From the GLOBAL LEADERS Trial.

Can J Cardiol 2020 Feb 21. Epub 2020 Feb 21.

Andrzej Frycz Modrzewski Krakow University, Krakow, Poland; American Heart of Poland, Chrzanow, Poland.

Background: Radial artery access has been shown to reduce mortality and bleeding events, especially in patients with acute coronary syndromes. Despite this, interventional cardiologists experienced in femoral artery access still prefer that route for percutaneous coronary intervention. Little is known regarding the merits of each vascular access in patients stratified by their risk of bleeding. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.01.029DOI Listing
February 2020

Re-evaluation of birth trends and pregnancy complications among female urologists: Have we made any progress?

Neurourol Urodyn 2020 May 25. Epub 2020 May 25.

Division of Urology, Cedars Sinai Medical Center, Beverly Hills, California.

Aims: Females are becoming surgeons at ever-increasing rates and doing so while many have or wish to have children. This study follows up on a 2007 effort to study the problems and conditions such women faced. We ask here if these challenges are different after a decade that included changes in working rules. Read More

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http://dx.doi.org/10.1002/nau.24409DOI Listing

Trending topics in orthodontics research during the last three decades: a longitudinal bibliometric study on the top-cited articles.

Orthod Craniofac Res 2020 May 25. Epub 2020 May 25.

Department of Dentistry, Universidad Europea de Valencia, Valencia, Spain.

Objective: To perform a bibliometric analysis on the top-cited articles over the last three decades from 1989 to 2018, using a longitudinal set-up, in order to analyse how articles' features have evolved over time.

Setting And Sample Population: A sample of 312 articles divided in three subgroups of 104 top-cited articles for each decade were included. The h-index value was used to determine the sample size MATERIALS AND METHODS: The articles were identified through a search in the category "dentistry oral surgery and medicine" of the Web of Science database. Read More

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http://dx.doi.org/10.1111/ocr.12396DOI Listing

Getting the Baby on a Schedule: Dutch and American Mothers' Ethnotheories and the Establishment of Diurnal Rhythms in Early Infancy.

New Dir Child Adolesc Dev 2020 May 25. Epub 2020 May 25.

The Council for Health and Society.

One of the earliest challenges for infants and their parents is developing a diurnal sleep-wake cycle. Although the human biological rhythm is circadian by nature, its development varies across cultures, based in part on "zeitgebers" (German: literally "time-givers") or environmental cues. This study uses the developmental niche framework by Super and Harkness to address two different approaches to getting the baby on a schedule. Read More

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http://dx.doi.org/10.1002/cad.20336DOI Listing

Periodontal disease classifications and incident coronary heart disease in the Atherosclerosis Risk in Communities Study.

J Periodontol 2020 May 25. Epub 2020 May 25.

Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, MN, USA.

Background: Periodontal disease has been linked to coronary heart disease (CHD), but studies have been inconclusive. This study investigates the link between periodontal disease and incident CHD.

Methods: Baseline periodontal data from a full-mouth periodontal exam (n = 6,300) and CHD outcomes through 2017 were obtained from the Atherosclerosis Risk in Communities Study. Read More

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http://dx.doi.org/10.1002/JPER.19-0723DOI Listing

Coffee and tea consumption in the early adult lifespan and left ventricular function in middle age: the CARDIA study.

ESC Heart Fail 2020 May 25. Epub 2020 May 25.

Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Aims: The long-term impact of coffee or tea consumption on subclinical left ventricular (LV) systolic or diastolic function has not been previously studied. We examined the association between coffee or tea consumption beginning in early adulthood and cardiac function in midlife.

Methods And Results: We investigated 2735 Coronary Artery Risk Development in Young Adults (CARDIA) study participants with long-term total caffeine intake, coffee, and tea consumption data from three visits over a 20 year interval and available echocardiography indices at the CARDIA Year-25 exam (2010-2011). Read More

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http://dx.doi.org/10.1002/ehf2.12684DOI Listing

The role of sodium channels in sudden unexpected death in pediatrics.

Mol Genet Genomic Med 2020 May 25:e1309. Epub 2020 May 25.

Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.

Background: Sudden Unexpected Death in Pediatrics (SUDP) is a tragic event, likely caused by the complex interaction of multiple factors. The presence of hippocampal abnormalities in many children with SUDP suggests that epilepsy-related mechanisms may contribute to death, similar to Sudden Unexplained Death in Epilepsy. Because of known associations between the genes SCN1A and SCN5A and sudden death, and shared mechanisms and patterns of expression in genes encoding many voltage-gated sodium channels (VGSCs), we hypothesized that individuals dying from SUDP have pathogenic variants across the entire family of cardiac arrhythmia- and epilepsy-associated VGSC genes. Read More

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http://dx.doi.org/10.1002/mgg3.1309DOI Listing

Clinicopathologic predictors of survival in buccal squamous cell carcinoma.

J Oral Pathol Med 2020 May 25. Epub 2020 May 25.

Department of Otorhinolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN, United States.

Background: Buccal squamous cell carcinoma (SCC) is a locoregionally aggressive malignancy, representing a small subset of oral cancers in North America. We investigated the prognostic value of several clinicopathologic factors in a cohort of patients diagnosed with buccal SCC.

Methods: Between years 1992 and 2017, 52 patients were diagnosed with conventional buccal SCC. Read More

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http://dx.doi.org/10.1111/jop.13046DOI Listing

Engaging South Asian youth and families: A clinical review.

Int J Soc Psychiatry 2020 May 25:20764020922881. Epub 2020 May 25.

Department of Health Law, Policy & Management, Boston University School of Public Health, Boston, MA, USA.

Objective: South Asians (SAs), a rapidly growing minority group in the United States are underrepresented in mental health research. They represent a unique sub-group of Asian immigrants in that their journey to the United States in the last 50 years was driven by the pursuit of academic and career opportunities. Our goal is to provide a topical overview of factors contributing to the mental health challenges of South Asian American (SAA) youth and to describe culturally sensitive approaches that would provide effective treatment for SAA youth and their families. Read More

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http://dx.doi.org/10.1177/0020764020922881DOI Listing

Awareness of and attitudes toward pre-exposure prophylaxis among African American women living in low-income neighborhoods in a Southeastern city.

AIDS Care 2020 May 25:1-5. Epub 2020 May 25.

Department of Health Behavior, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

African American women in the South are disproportionately affected by HIV but have often been ignored in HIV prevention efforts, including in the rollout of pre-exposure prophylaxis (PrEP). To inform strategies to promote PrEP awareness and access in this population, we conducted a venue-based community survey with 53 African American women living in low-income neighborhoods of a Southeastern city to understand women's knowledge of and attitudes toward PrEP. Awareness of PrEP was very low (37%) with only 16% being aware that PrEP is used for HIV prevention. Read More

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http://dx.doi.org/10.1080/09540121.2020.1769834DOI Listing

Barriers and motivators to pre-exposure prophylaxis uptake among Black and Latina transgender women in Los Angeles: perspectives of current PrEP users.

AIDS Care 2020 May 23:1-9. Epub 2020 May 23.

Department of Family Medicine, University of California, Los Angeles, CA, USA.

The purpose of this qualitative study was to identify barriers and motivators to PrEP uptake from the perspective of Black and Latina transgender women (TW) who are currently using PrEP to suggest intervention and outreach activities to increase PrEP uptake in this population. The Information-Motivation-Behavioral Skills Model guided the development of the semi-structured interview guide. A thematic analysis approach was used to analyze the data. Read More

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http://dx.doi.org/10.1080/09540121.2020.1769835DOI Listing

Peripartum thromboprophylaxis.

BJOG 2020 May 24. Epub 2020 May 24.

Baylor College of Medicine, Houston, Texas, USA.

Prophylaxis with low-molecular-weight heparin during pregnancy is advocated for women at risk of venous thromboembolism due to its single daily dosing, expectable therapeutic response and low risk of bleeding occurrences (ACOG Practice Bulletin No. 196. American College of Obstetricians and Gynecologists. Read More

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http://dx.doi.org/10.1111/1471-0528.16332DOI Listing

Birth plan alterations among American women in response to COVID-19.

Health Expect 2020 May 24. Epub 2020 May 24.

Department of Anthropology, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.1111/hex.13077DOI Listing

Alternative type 2 diabetes screening tests may reduce the number of U.S. adults with undiagnosed diabetes.

Diabet Med 2020 May 24. Epub 2020 May 24.

Section of General Internal Medicine, University of Chicago, Chicago, IL, USA.

Aim: To evaluate the U.S. population-level impact of two alternatives for initial type 2 diabetes screening [opportunistic random plasma glucose (RPG) > 6. Read More

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http://dx.doi.org/10.1111/dme.14330DOI Listing

COVID-19 and Hidden Housing Vulnerabilities: Implications for Health Equity, New Haven, Connecticut.

AIDS Behav 2020 May 24. Epub 2020 May 24.

Department of Sociology, American University, 4400 Massachusetts Ave, Washington DC, NW, 20016, USA.

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http://dx.doi.org/10.1007/s10461-020-02921-2DOI Listing

Does oncoplastic surgery increase immediate (30-day) postoperative complications? An analysis of the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database.

Breast Cancer Res Treat 2020 May 25. Epub 2020 May 25.

Division of General Surgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.

Purpose: Although there has been a significant increase in the use of oncoplastic surgery (OPS), data on the postoperative safety of this approach are limited compared to traditional lumpectomy. This study aimed to compare the immediate (30-day) postoperative complications associated with OPS and traditional lumpectomy.

Methods: An analysis of the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database was performed on women with breast cancer who underwent OPS or traditional lumpectomy. Read More

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http://dx.doi.org/10.1007/s10549-020-05665-8DOI Listing

Global, regional and time-trend prevalence of central obesity: a systematic review and meta-analysis of 13.2 million subjects.

Eur J Epidemiol 2020 May 24. Epub 2020 May 24.

Department of Global Health, School of Public Health, Peking University, 38, Xue Yuan Road, Haidian District, Beijing, China.

We aimed to examine the global prevalences of central obesity according to age, sex, race, place of residence, geographical region, national income level, and the definitions of central obesity. MEDLINE and Embase were searched. Studies with sample size of ≥ 500 and investigated individuals aged ≥ 15 years were included. Read More

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http://dx.doi.org/10.1007/s10654-020-00650-3DOI Listing

National trends in the use of PSA, urinalysis, and digital rectal exam for evaluation of lower urinary tract symptoms in men.

World J Urol 2020 May 24. Epub 2020 May 24.

Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave., Boston, MA, 02215, USA.

Purpose: The purpose of this study was to describe the practices of primary care physicians (PCPs) and urologists in their implementation of the 2010 American Urological Association (AUA) recommendations for the management of benign prostatic hyperplasia (BPH) in a nationally representative sample.

Methods: Data collected from 2008 to 2015 in the National Ambulatory Medical Care Survey (NAMCS) were used. Men aged 45 and older who presented with either a new complaint or exacerbation of lower urinary tract symptoms (LUTS) were included. Read More

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http://dx.doi.org/10.1007/s00345-020-03261-5DOI Listing

Meta-analysis of prognostic factors of overall survival in patients undergoing oesophagectomy for oesophageal cancer.

Dis Esophagus 2020 May 25. Epub 2020 May 25.

Department of Upper Gastrointestinal Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

Introduction: Currently, the American Joint Commission on Cancer (AJCC) staging system is used for prognostication for oesophageal cancer. However, several prognostically important factors have been reported but not incorporated. This meta-analysis aimed to characterize the impact of preoperative, operative, and oncological factors on the prognosis of patients undergoing curative resection for oesophageal cancer. Read More

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http://dx.doi.org/10.1093/dote/doaa038DOI Listing

Declines in pneumonia mortality following the introduction of pneumococcal conjugate vaccines in Latin American and Caribbean countries.

Clin Infect Dis 2020 May 25. Epub 2020 May 25.

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT.

Background: Pneumococcal conjugate vaccines (PCVs) are recommended for use in pediatric immunization programs worldwide. Few data are available on their effect against mortality. We present a multi-country evaluation of the population-level impact of PCVs against death due to pneumonia in children <5 years. Read More

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http://dx.doi.org/10.1093/cid/ciaa614DOI Listing

Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America: the ESTAMPA screening study protocol.

BMJ Open 2020 May 24;10(5):e035796. Epub 2020 May 24.

Prevention and Implementation Group, International Agency for Research on Cancer, Lyon, Rhône-Alpes, France.

Introduction: Human papillomavirus (HPV) testing is replacing cytology in primary screening. Its limited specificity demands using a second (triage) test to better identify women at high-risk of cervical disease. Cytology represents the immediate triage but its low sensitivity might hamper HPV testing sensitivity, particularly in low-income and middle-income countries (LMICs), where cytology performance has been suboptimal. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-035796DOI Listing

10-Valent pneumococcal non-typeable protein D conjugate vaccine (PHiD-CV10) versus 13-valent pneumococcal conjugate vaccine (PCV13) as a booster dose to broaden and strengthen protection from otitis media (PREVIX_BOOST) in Australian Aboriginal children: study protocol for a randomised controlled trial.

BMJ Open 2020 May 24;10(5):e033511. Epub 2020 May 24.

Child Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia

Introduction: and non-typeable (NTHi) are major otitis media pathogens that densely co-colonise the nasopharynx and infect the middle ear of Australian Aboriginal infants from very early in life. Our co-primary hypotheses are that at 18 months of age infants receiving 10-valent pneumococcal protein D conjugate vaccine (PHiD-CV10) compared with those receiving 13-valent pneumococcal conjugate vaccine (PCV13) as a booster at 12 months of age will have higher antibody levels to protein D and that infants receiving PCV13 will have higher antibody levels to PCV13-only serotypes 3, 6A and 19A.

Methods And Analyses: Our randomised controlled trial will enrol 270 Aboriginal children at 12 months of age to a booster dose of either PHiD-CV10 or PCV13. Read More

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http://dx.doi.org/10.1136/bmjopen-2019-033511DOI Listing

Renal Sympathetic Denervation: A Comprehensive Review.

Curr Probl Cardiol 2020 May 3:100598. Epub 2020 May 3.

In 2017, the American College of Cardiology and American Heart Association released its updated blood pressure guidelines, redefining hypertension to be any systolic blood pressure ≥130 mm Hg or diastolic blood pressure ≥80 mm Hg. Among United States adults, these new parameters increased the prevalence of hypertension from 72.2 million (31. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2020.100598DOI Listing

COVID 19 crisis: Maintaining brachytherapy access and strategies for risk mitigation.

Brachytherapy 2020 Apr 29. Epub 2020 Apr 29.

President, American Brachytherapy Society, Department of Radiation Oncology, Monument Health Cancer Care Institute, Rapid City, SD. Electronic address:

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http://dx.doi.org/10.1016/j.brachy.2020.04.007DOI Listing

Efficacy of dietary intervention or in combination with exercise on primary prevention of cardiovascular disease: A systematic review.

Nutr Metab Cardiovasc Dis 2020 Mar 17. Epub 2020 Mar 17.

Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands, IDISBA & CIBEROBN, E-07122 Palma de Mallorca, Spain. Electronic address:

Background And Aim: Lifestyle factors heavily influence the development of cardiovascular disease (CVD); therefore, interventions delivering adequate lifestyle changes may improve the prognosis among patients at cardiovascular (CV) risk. Recently published research on the effectiveness of dietary and exercise intervention programmes, alone or combined, on reducing risk factors associated with CVD as well as preventing CV events have been now assessed.

Methods And Results: Using the Medline database via PubMed, we searched for prospective studies published between January 2000 and January 2020 assessing the efficacy of dietary interventions alone or in combination with exercise on reducing CV risk factors or events in human adults at risk. Read More

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http://dx.doi.org/10.1016/j.numecd.2020.02.020DOI Listing

Physicians' Use of Evidence-Based Strategies to Increase Adult Vaccination Uptake.

Am J Prev Med 2020 May 21. Epub 2020 May 21.

Adult and Child Consortium for Health Outcomes Research and Delivery Science, University of Colorado Anschutz Medical Campus and Children's Hospital Colorado, Aurora, Colorado; Department of Pediatrics Children's Hospital Colorado, Aurora, Colorado.

Introduction: This study assesses the following among primary care physicians: (1) the use of evidence-based strategies to improve adult vaccination rates, (2) the number of strategies employed simultaneously, and (3) characteristics associated with assessing adult vaccinations at each visit.

Methods: An internet and mail survey was administered between December 2015 and January 2016 on primary care physicians designed to be representative of the American College of Physicians and American Academy of Family Physicians memberships. Data analysis was conducted in 2019. Read More

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http://dx.doi.org/10.1016/j.amepre.2020.03.020DOI Listing

Prevalence of Fasciola hepatica infection in Galba cousini and Galba schirazensis from an Andean region of Ecuador.

Vet Parasitol Reg Stud Reports 2020 Apr 19;20:100390. Epub 2020 Feb 19.

Instituto de Investigación en Zoonosis (CIZ), Ciudadela Universitaria, Universidad Central del Ecuador, EC170521 Quito, Ecuador; Facultad de Medicina Veterinaria y Zootecnia, Ciudadela Universitaria, Universidad Central del Ecuador, EC170521 Quito, Ecuador. Electronic address:

Some Lymnaeid snails are intermediate hosts of the liver fluke Fasciola hepatica, the causal agent of fasciolosis, a zoonotic parasitic disease. Human and livestock fasciolosis has been reported in a highland community located in the Chimborazo Province of the Ecuadorian Andes. However, no previous study has been carried out to identify which snail species act as intermediate host/s of F. Read More

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http://dx.doi.org/10.1016/j.vprsr.2020.100390DOI Listing

Examining the association of health literacy and numeracy with prostate-related knowledge and prostate cancer treatment regret.

Urol Oncol 2020 May 21. Epub 2020 May 21.

Department of Urology, Vanderbilt University Medical Center, Nashville, TN. Electronic address:

Introduction: Educational materials used in prostate cancer shared decision-making are often written above the health literacy levels of the patients that may benefit the most from such tools. Poor understanding the oncologic and functional outcomes of prostate cancer treatment may influence patient regret during this process. In this study, we assess the association between health literacy, numeracy, prostate-related knowledge and treatment regret in a diverse population. Read More

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http://dx.doi.org/10.1016/j.urolonc.2020.04.007DOI Listing

Nerve transfers in the upper extremity: A review.

Injury 2020 May 21. Epub 2020 May 21.

Department of Orthopedic Surgery and Traumatology, Saint Georges University Medical Center, Balamand University, P.O. Box 166378, Achrafieh, Beirut, 1100 2807, Lebanon.

Injury of the brachial plexus and peripheral nerve often result in significant upper extremity dysfunction and disability. Nerve transfers are replacing other techniques as the gold standard for brachial plexus and other proximal peripheral nerve injuries. These transfers require an intimate knowledge of nerve topography, a technically demanding Intraneural dissection and require extensive physical therapy for retraining. Read More

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http://dx.doi.org/10.1016/j.injury.2020.04.015DOI Listing

Assessment and Management of the High-Risk Dental Patient with Active Substance Use Disorder.

Dent Clin North Am 2020 Jul 16;64(3):547-558. Epub 2020 Apr 16.

Department of Diagnostic Sciences, Center for Pain Medicine, Tufts University School of Dental Medicine, 1 Kneeland Street, Boston, MA 02111, USA; Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, MA, USA. Electronic address:

Every dentist cares for patients with a history of substance use disorder (SUD), regardless of a patient's socioeconomic status, education, or ethnicity. SUD is a global epidemic, with approximately 8% of the general US population meeting diagnostic criteria for a SUD and more than 20% of the global population experiencing a SUD. The importance of understanding how to identify substance use, manage patients with a SUD, and offer appropriate referral is essential for all dental professionals. Read More

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http://dx.doi.org/10.1016/j.cden.2020.02.004DOI Listing

Pharmacokinetics and analgesic effects of intravenous, intramuscular or subcutaneous buprenorphine in dogs undergoing ovariohysterectomy: a randomized, prospective, masked, clinical trial.

BMC Vet Res 2020 May 24;16(1):154. Epub 2020 May 24.

Department of Veterinary Biomedical Sciences, Faculty of Veterinary Medicine, Université de Montréal, Saint-Hyacinthe, QC, Canada.

Background: Buprenorphine is used for canine postoperative pain management. This study aimed to describe the pharmacokinetics and evaluate the analgesic efficacy of buprenorphine (Simbadol, 1.8 mg/mL) administered by different routes in dogs undergoing ovariohysterectomy. Read More

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http://dx.doi.org/10.1186/s12917-020-02364-wDOI Listing

Preliminary study on HIV status disclosure to perinatal infected children: retrospective analysis of administrative records from a pediatric HIV clinic in the southern United States.

BMC Res Notes 2020 May 24;13(1):253. Epub 2020 May 24.

Department of Pediatrics, School of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, 35294, USA.

Objective: The World Health Organization recommends disclosing HIV-status between 6 and 12 years; American Academy of Pediatrics recommends that children are informed at "school age." Neither suggests an optimal age when children should learn of their status to improve viral load suppression. Considering that virally suppressed people do not transmit HIV and that interrupting the transmission cycle is critical to ending the HIV epidemic, our objective is to examine the relationship between age of disclosure and viral load suppression by evaluating data from a pediatric HIV clinic in the southern United States. Read More

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http://dx.doi.org/10.1186/s13104-020-05097-zDOI Listing

Association between morbidity of non-communicable disease and employment status: a comparison between Korea and the United States.

BMC Public Health 2020 May 24;20(1):763. Epub 2020 May 24.

Korea Medical Institute, Seoul, Republic of Korea.

Background: Globally, the prevalence of chronic disease continues to rise and is likely to grow further over the coming decades due to population ageing. Since older age is associated closely with development of chronic disease, it stands to reason that demographic changes will increase the proportion of older workers with chronic disease. The aim of the present study was to determine how chronic diseases affect employment status in Korea and the USA. Read More

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http://dx.doi.org/10.1186/s12889-020-08883-3DOI Listing

Returning to care after incarceration with HIV: the French Guianese experience.

BMC Public Health 2020 May 24;20(1):754. Epub 2020 May 24.

Inserm CIC Antilles-Guyane INSERM 1424 (Pole Guyane), Universite de Guyane, Cayenne, France.

Background: HIV prevalence in correctional facilities may be 2 to 10 times higher than in the general adult population. Antiretroviral therapy (ART) interruption is frequent after an incarceration. This, in combination with post-release high-risk behaviors, may have detrimental consequences on the epidemic. Read More

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http://dx.doi.org/10.1186/s12889-020-08772-9DOI Listing

Data-based RNA-seq simulations by binomial thinning.

Authors:
David Gerard

BMC Bioinformatics 2020 May 24;21(1):206. Epub 2020 May 24.

Department of Mathematics and Statistics, American University, Massachusetts Ave NW, Washington, DC, 20016, USA.

Background: With the explosion in the number of methods designed to analyze bulk and single-cell RNA-seq data, there is a growing need for approaches that assess and compare these methods. The usual technique is to compare methods on data simulated according to some theoretical model. However, as real data often exhibit violations from theoretical models, this can result in unsubstantiated claims of a method's performance. Read More

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http://dx.doi.org/10.1186/s12859-020-3450-9DOI Listing

Association of Helicobacter pylori babA2 gene and gastric cancer risk: a meta-analysis.

BMC Cancer 2020 May 24;20(1):465. Epub 2020 May 24.

Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.

Background: The association of Helicobacter pylori (H. pylori) babA2 gene with gastric cancer (GC) was reported by several studies, but results were inconsistent. This meta-analysis was performed to investigate the relationship between H. Read More

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http://dx.doi.org/10.1186/s12885-020-06962-7DOI Listing

A novel null allele, HLA-DPA1*01:35 N in a European American Male from Pennsylvania, USA.

HLA 2020 May 24. Epub 2020 May 24.

Department of Pathology, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania.

A non-sense mutation in either DPA1*01:03:01:02 or DPA1* 01:03:01:05/01:03:01:15 results in the novel allele, HLA-DPA1*01:35 N. This article is protected by copyright. All rights reserved. Read More

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http://dx.doi.org/10.1111/tan.13944DOI Listing

Re-hospitalization after pediatric kidney transplant: A single-center study.

Pediatr Transplant 2020 May 24:e13717. Epub 2020 May 24.

Division of Nephrology, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.

Background: Little data exist on re-hospitalization rates in pediatric kidney recipients (KTx) particularly with the evolution of transplant immunosuppression.

Methods: In a single-center, retrospective study of pediatric KTx between 2006 and 2016, we assessed re-hospitalization after KTx admission, stratified by whether the re-admit was early (<30 days post-KTx discharge) or late (>30 days), and compared two different immunosuppression eras (one with and one without steroids).

Results: Of 197 KTx, 156 (79%) patients were re-hospitalized in 1st year, 85 (56%) within 30 days of discharge (total 490 1st year re-hospitalizations). Read More

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http://dx.doi.org/10.1111/petr.13717DOI Listing

Racial/ethnic variations in weight management among patients with overweight and obesity status who are served by health centres.

Clin Obes 2020 May 24:e12372. Epub 2020 May 24.

Bureau of Primary Health Care, Health Resources and Services Administration, U.S. Department of Health and Human Services , Rockville, Maryland, USA.

This study sought to examine racial/ethnic variations in receipt of provider recommendations on weight loss, patient adherence, perception of weight, attempts at weight loss and actual weight loss among patients with overweight/obesity status at Health Resources and Services Administration-funded health centres (HC). We used a 2014 nationally representative survey of adult HC patients with overweight/obesity status (PwOW/OB) last year and reported the HC was their usual source of care (n = 3517). We used logistic regression models to assess the interaction of race/ethnicity and having obesity in (1) provider recommendations of diet or (2) exercise, (3) patient adherence to diet or (4) exercise, (5) perceptions of weight and (6) weight loss attempts. Read More

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http://dx.doi.org/10.1111/cob.12372DOI Listing

Validation of a wrist-type home nocturnal blood pressure monitor in the sitting and supine position according to the ANSI/AAMI/ISO81060-2:2013 guidelines: Omron HEM-9601T.

J Clin Hypertens (Greenwich) 2020 May 24. Epub 2020 May 24.

Tohoku Institute for Management of Blood Pressure, Sendai, Japan.

This study aimed to validate the accuracy of the Omron HEM-9601T, an automatic wrist-type device for self-blood pressure (BP) measurement with a timer function for automatic measurement of nocturnal BP, in the sitting position according to the American National Standards Institute/Association for the Advancement of Medical Instrumentation/International Organization for Standardization (ANSI/AAMI/ISO) 81060-2:2013 guidelines, and to assess its performance in the supine position by applying the same protocol as conducted in the sitting position. The mean differences between the reference BPs and HEM-9601T readings were 1.2 ± 6. Read More

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http://dx.doi.org/10.1111/jch.13864DOI Listing

Environmental contaminants and male infertility: Effects and mechanisms.

Andrologia 2020 May 24:e13646. Epub 2020 May 24.

American Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH, USA.

The escalating prevalence of male infertility and decreasing trend in sperm quality have been correlated with rapid industrialisation and the associated discharge of an excess of synthetic substances into the environment. Humans are inevitably exposed to these ubiquitously distributed environmental contaminants, which possess the ability to intervene with the growth and function of male reproductive organs. Several epidemiological reports have correlated the blood and seminal levels of environmental contaminants with poor sperm quality. Read More

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http://dx.doi.org/10.1111/and.13646DOI Listing

The Role of Anti-PD-1/PD-L1 in the Treatment of Skin Cancer.

BioDrugs 2020 May 23. Epub 2020 May 23.

Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

Skin cancers remain the most common group of cancers globally, and the incidence continues to rise. Although localized skin cancers tend to have excellent outcomes following surgical excisions, the less common cases that become surgically unresectable or metastatic have been associated with poor prognosis and suboptimal treatment responses to cytotoxic chemotherapy. Development of monoclonal antibodies to programmed cell death-1 receptor and its ligand (PD-1/PD-L1) have transformed the management of metastatic melanoma, squamous cell carcinoma, and Merkel cell carcinoma. Read More

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http://dx.doi.org/10.1007/s40259-020-00428-9DOI Listing

The Ramapough Lunaape Nation: Facing Health Impacts Associated with Proximity to a Superfund Site.

J Community Health 2020 May 23. Epub 2020 May 23.

Department of Environmental Medicine, New York University Grossman School of Medicine, 341 East 25th Street, New York, NY, 10010, USA.

This study aimed to evaluate self-reported exposure to the Ringwood Mines/Landfill Superfund Site in relation to chronic health outcomes among members of the Ramapough Lunaape Turtle Clan nation and other local residents of Ringwood, New Jersey. Community surveys on personal exposure to the nearby Superfund site, self-reported health conditions, and demographics were conducted with 187 members of the Ramapough Lunaape Turtle Clan Nation and non-Native Americans residing in Ringwood, New Jersey from December 2015 to October 2016. Multiple logistic regression was performed to assess the association between ethnicity and a Superfund site exposure score developed for this study, as well as between exposure score and several chronic health conditions. Read More

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http://dx.doi.org/10.1007/s10900-020-00848-2DOI Listing

Genetic markers for treatment-related pancreatitis in a cohort of Hispanic children with acute lymphoblastic leukemia.

Support Care Cancer 2020 May 24. Epub 2020 May 24.

Department of Pediatrics, University of Texas Health Science Center San Antonio, San Antonio, TX, USA.

Purpose: Treatment-related pancreatitis (TRP) is a serious complication occurring in children with acute lymphoblastic leukemia (ALL). Those affected are at high risk for severe organ toxicity and treatment delays that can impact outcomes. TRP is associated with asparaginase, a standard therapeutic agent in childhood ALL. Read More

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http://dx.doi.org/10.1007/s00520-020-05530-wDOI Listing

Identifying Modifiable Factors Linking Parenting and Sleep in Racial/Ethnic Minority Children.

J Pediatr Psychol 2020 May 24. Epub 2020 May 24.

Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia.

Background: Young children from racial and ethnic minority backgrounds are at risk for poor sleep, yet few studies have tested behavioral interventions in diverse samples. This study tests factors that could contribute to associations between parenting skills and child sleep to inform interventions for children at risk of poor sleep outcomes. Specifically, we examined household chaos, caregiver sleep knowledge, and caregiver sleep quality as putative mediators that may be relevant to interventions seeking to improve child sleep. Read More

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http://dx.doi.org/10.1093/jpepsy/jsaa034DOI Listing