372,098 results match your criteria American journal of respiratory medicine : drugs devices and other interventions[Journal]


A systematic review on reported outcomes and outcome measures in female idiopathic chronic pelvic pain for the development of a core outcome set.

BJOG 2020 Jul 12. Epub 2020 Jul 12.

Department of Obstetrics and Gynaecology, St Helier University Hospitals NHS Trust, Epsom &, London, KT18 7EG, United Kingdom.

Background: A core outcome set (COS) is required to address inconsistencies in outcome reporting in chronic pelvic pain (CPP) trials.

Objectives: Evaluation of reported outcomes and selected outcome measures in CPP trials by producing a comprehensive inventory to inform a COS.

Search Strategy: Systematic review of RCT identified from Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE and MEDLINE databases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1471-0528.16412DOI Listing

A Step Towards Standardization: Results of Two National Surveys of Best Practices in Donation after Circulatory Death Liver Recovery and Recommendations from The American Society of Transplant Surgeons and Association of Organ Procurement Organizations.

Clin Transplant 2020 Jul 11:e14035. Epub 2020 Jul 11.

Department of Surgery, University of Iowa Carver College of Medicine, Iowa City, IA, United States.

Donation after circulatory death (DCD) liver allografts remain underutilized. Inconsistent processes for DCD procurement may contribute to allograft discard. Optimal surgical and organ procurement organization (OPO) practices for DCD liver recovery should be developed and adopted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ctr.14035DOI Listing

A multicenter evaluation of heterogeneity in cellular therapy processing laboratory procedure times to assess workload capacity.

Transfusion 2020 Jul 12. Epub 2020 Jul 12.

American Red Cross, Biomedical Services Headquarters, Washington, DC, USA.

Background: Growth in size and complexity of clinical hematopoietic progenitor cell (HPC) transplant programs necessitates parallel increases in cellular therapy laboratory (CTL) workload. Typically individually developed, HPC product processing is labor and time intensive. Variation in procedure type and numbers across CTLs complicates direct comparisons, and benchmark data are not readily available. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/trf.15899DOI Listing

A radiomics platform for computing imaging features from µCT images of Thoroughbred racehorse proximal sesamoid bones: benchmark performance and evaluation.

Equine Vet J 2020 Jul 12. Epub 2020 Jul 12.

Clinical Sciences, Cornell University, Ithaca, New York, USA.

Background: Proximal sesamoid bone (PSB) fractures are the most common fatal musculoskeletal injury in North American racehorses. Computed tomography has the potential to detect morphological changes in bone structure but can be challenging to analyse reliably and quantitatively.

Objectives: To develop a radiomics platform that allows the comparison of features from micro-CTs (µCT) of PSB in horses that sustained catastrophic fractures with horses that did not. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/evj.13321DOI Listing

Risk factors of venous thromboembolism in patients with benign and malignant musculoskeletal tumors: a dual database analysis.

Int Orthop 2020 Jul 11. Epub 2020 Jul 11.

Department of Orthopaedics, Rutgers New Jersey Medical School, 140 Bergen Street, ACC D1610, Newark, NJ, 07103, USA.

Purpose: Venous thromboembolism (VTE) is a potentially life-threatening condition associated with both orthopaedic surgery and tumour growth. In this study, we identify risk factors associated with VTE in patients with musculoskeletal tumours using two national datasets.

Methods: The ACS-NSQIP and NIS databases were queried for patients undergoing surgery with a diagnosis of benign or malignant musculoskeletal tumours. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00264-020-04707-6DOI Listing

Challenges in predicting the outcome of competition based on climate change-induced phenological and body size shifts.

Oecologia 2020 Jul 11. Epub 2020 Jul 11.

Department of Biology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH, 44106, USA.

Climate change is creating warmer, earlier springs, which are causing the phenology of many organisms to shift. Additionally, as temperatures increase, the body size of many ectotherms is decreasing. However, phenological and body size shifts are not occurring at the same rates across species, even in species that live in close proximity or have similar life history. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00442-020-04705-wDOI Listing

Comparing Perceptions and Decisional Conflict Towards Participation in Cancer Clinical Trials Among African American Patients Who Have and Have Not Participated.

J Cancer Educ 2020 Jul 11. Epub 2020 Jul 11.

Fox Chase Cancer Center, Philadelphia, PA, USA.

Despite efforts to increase the diversity of cancer clinical trial participants, African Americans are still underrepresented. While perceptions of participation have been studied, the objective of this study was to compare perceptions and decisional conflict towards clinical trials among African American cancer patients who have and have not participated in clinical trials to identify key areas for intervention. Post hoc analysis also looked at whether they had been asked to participate and how that group differed from those who did. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13187-020-01827-wDOI Listing

Correction to: 2020 CIS Annual Meeting: Immune Deficiency & Dysregulation North American Conference.

J Clin Immunol 2020 Jul 11. Epub 2020 Jul 11.

Pediatric Immunologist/Allergist, Department of Pediatrics, Alberta Children's Hospital, Calgary, Alberta, Canada.

The abstract with Submission ID#809896 has been revised due to duplicate title and the missing main author. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10875-020-00818-2DOI Listing

Financial toxicity associated with a cancer diagnosis in publicly funded healthcare countries: a systematic review.

Support Care Cancer 2020 Jul 11. Epub 2020 Jul 11.

Population Health Sciences Institute, Newcastle University Centre for Cancer, Newcastle University, Newcastle upon Tyne, UK.

Purpose: Financial toxicity related to cancer diagnosis and treatment is a common issue in developed countries. We seek to systematically summarize the extent of the issue in very high development index countries with publicly funded healthcare.

Methods: We identified articles published Jan 1, 2005, to March 7, 2019, describing financial burden/toxicity experienced by cancer patients and/or informal caregivers using OVID Medline Embase and PsychInfo, CINAHL, Business Source Complete, and EconLit databases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00520-020-05620-9DOI Listing

Genomic analysis of the only blind cichlid reveals extensive inactivation in eye and pigment formation genes.

Genome Biol Evol 2020 Jul 11. Epub 2020 Jul 11.

Department of Ichthyology, American Museum of Natural History, New York, NY, USA.

Trait loss represents an intriguing evolutionary problem, particularly when it occurs across independent lineages. Fishes in light-poor environments often evolve "troglomorphic" traits, including reduction or loss of both pigment and eyes. Here we investigate the genomic basis of trait loss in a blind and depigmented African cichlid, Lamprologus lethops, and explore evolutionary forces (selection and drift) that may have contributed to these losses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/gbe/evaa144DOI Listing

Teaching the use of framing and decontextualization to address context-based bias in psychiatry.

Asian J Psychiatr 2020 Jul 2;54:102276. Epub 2020 Jul 2.

Saint Joseph University, Department of Urology, Beirut, Lebanon.

The framing effect in medical decision making is a type of cognitive bias that can lead a medical trainee at undergraduate and graduate level to reach a diagnosis or take action based on emotional states induced by the frame in which the information has been approached. This literature review on the framing effect in medical decision making will be done in the context of a case presentation in which the framing of scientific information may lead to conflicting decisions in psychiatry. As a matter of fact, debiasing techniques which help medical students/residents become aware of the fact that they might be easily influenced by the frame used in scientific data, have started to be implemented in medical teaching programs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajp.2020.102276DOI Listing

Barriers and facilitators of asthma management as experienced by African American caregivers of children with asthma: An integrative review.

J Pediatr Nurs 2020 Jul 9;55:40-74. Epub 2020 Jul 9.

Department of Public Health Sciences, University of Miami Miller School of Medicine, 1600 NW 10(th) Ave., Miami, FL 33136, United States of America. Electronic address:

Introduction: African American children with asthma demonstrate significant health disparities and poor health outcomes. Understanding the burdens faced by parents and caregivers of children with asthma may be helpful to develop future interventions to address this disparity.

Purpose: The purpose of this integrative review was to reveal the barriers and facilitators of child asthma management experienced by African American caregivers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pedn.2020.06.012DOI Listing

Reactive balance responses to an unexpected slip perturbation in individuals with incomplete spinal cord injury.

Clin Biomech (Bristol, Avon) 2020 Jul 2;78:105099. Epub 2020 Jul 2.

College of Kinesiology, University of Saskatchewan, Saskatchewan, Canada.

Background: Frequent falls while walking among individuals with incomplete spinal cord injury may suggest impairments in reactive balance control; however, reactive balance control during walking has not been studied in this population. The objective was to compare reactive balance control with respect to changes in margin of stability, onset of arm and heel responses, and onset and magnitude of muscle activity following an unexpected slip perturbation in individuals with incomplete spinal cord injury and able-bodied individuals.

Methods: Kinematic and electromyography data were obtained during normal walking and one unexpected slip. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinbiomech.2020.105099DOI Listing

Recognizing odontogenic sinusitis: A national survey of otolaryngology chief residents.

Am J Otolaryngol 2020 Jul 4;41(6):102635. Epub 2020 Jul 4.

Department of Otolaryngology, Henry Ford Hospital, 2799 West Grand Blvd, Detroit, MI 48202, USA.

Purpose: Odontogenic sinusitis is underrepresented in sinusitis literature as well as in the otolaryngology teaching curriculum sponsored by the American Academy of Otolaryngology-Head and Neck Surgery. Otolaryngologists and residents in training may therefore have a decreased awareness of the condition. The objective of this study was to survey otolaryngology chief residents toward the ends of their training to determine how often they considered odontogenic sinusitis as a cause of unilateral sinus disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjoto.2020.102635DOI Listing

Bone Health Management After Hematopoietic Cell Transplantation: An Expert Panel Opinion from the American Society for Transplantation and Cellular Therapy.

Biol Blood Marrow Transplant 2020 Jul 9. Epub 2020 Jul 9.

Division of Clinical Research, Fred Hutchinson Cancer Research Center; Department of Medicine, University of Washington, Seattle WA.

Bone health disturbances occur commonly after hematopoietic cell transplantation (HCT) with loss of bone mineral density (BMD) and avascular necrosis (AVN) being foremost. BMD loss is related to pre-transplant chemotherapy and radiation exposures, immunosuppressive therapy for graft-versus-host-disease (GVHD), and results from deficiencies in growth or gonadal hormones, disturbances in calcium and vitamin D homeostasis, as well as osteoblast and osteoclast dysfunction. While the pathophysiology of AVN remains unclear, high-dose glucocorticoid exposure is the most frequent association. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2020.07.001DOI Listing

INCIDENCE OF SIGNIFICANT FINDINGS OF MICROHEMATURIA WORKUP IN WOMEN - WHAT GUIDELINES WORK BEST?

Urology 2020 Jul 9. Epub 2020 Jul 9.

Northwell Health; Maimonides Medical Center. Electronic address:

Objective: To apply the American Urogynecological Society (AUGS)/American College of Obstetricians and Gynecologists (ACOG) recommendations of foregoing workup in patients under 50 years of age with less than 25 red cells per high-powered field, to a cohort of asymptomatic microscopic hematuria (AMH) patients, and assess diagnostic accuracy, sensitivity, specificity, positive and negative predictive value compared to the American Urologic Association (AUA) guidelines.

Methods: Retrospective review of female patients who underwent AMH evaluation from 2012 - 2015. The number of patients who would have avoided workup following the AUGS/ACOG recommendations was determined. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.urology.2020.06.046DOI Listing

The management of diabetes in everyday life study: Design and methods for a pragmatic randomized controlled trial comparing the effectiveness of text messaging versus health coaching.

Contemp Clin Trials 2020 Jul 9:106080. Epub 2020 Jul 9.

Center for Health System Improvement, University of Tennessee Health Science Center, Memphis, TN, United States of America; Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, United States of America.

Background African American patients with uncontrolled diabetes living in medically underserved areas need effective clinic-based interventions to improve self-care behaviors. Text messaging (TM) and health coaching (HC) are among the most promising low-cost population-based approaches, but little is known about their comparative effectiveness in real-world clinical settings. Objective Use a pragmatic randomized controlled trial design to determine the comparative effectiveness of TM and HC with enhanced usual care (EC) in African American adults with uncontrolled diabetes and multiple chronic health conditions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cct.2020.106080DOI Listing

A systematic review of asthma case definitions in 67 birth cohort studies.

Paediatr Respir Rev 2020 Feb 21. Epub 2020 Feb 21.

Centre for Longitudinal Research, University of Auckland, Auckland, New Zealand; Department of Paediatrics: Child & Youth Health, University of Auckland, Auckland, New Zealand; General Paediatrics, Starship Children's Hospital, Auckland, New Zealand. Electronic address:

Background: Birth cohort studies are a valuable source of information about potential risk factors for childhood asthma. To better understand similarities and variations in findings between birth cohort studies, the methodologies used to measure asthma require consideration.

Objective: To review and appraise the definitions of "asthma" used in birth cohort studies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prrv.2019.12.005DOI Listing
February 2020

Electronic cigarettes and e-cigarette/vaping product use associated lung injury (EVALI).

Paediatr Respir Rev 2020 Jun 11. Epub 2020 Jun 11.

Virginia Commonwealth University, Department of Pediatrics and the Children's Hospital of Richmond at VCU, Richmond, VA, United States. Electronic address:

Electronic cigarettes (e-cigarettes) are noncombustible tobacco products that have been promoted as safer alternatives to conventional cigarettes and beneficial tools for smoking cessation. However, e-cigarettes have been shown to produce aerosols with high concentrations of propylene glycol, glycerol, volatile organic compounds, and free radicals, which can lead to lung damage. Furthermore, e-cigarettes can deliver nicotine at concentrations higher than traditional combustibles, making them highly addictive. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.prrv.2020.06.003DOI Listing

Prevalence of Inadequate and Excessive Iodine Intake in a US Pregnancy Cohort.

Am J Obstet Gynecol 2020 Jul 9. Epub 2020 Jul 9.

Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI; Department of Pediatrics and Human Development, Michigan State University, East Lasing, MI.

Background: US iodine intake, estimated from the median urinary iodine concentration of population representative data, has declined by half since the 1970s which is problematic because maternal iodine intake is critical for fetal neurodevelopment. Relying on median urinary concentrations to assess iodine intake of populations is standard practice but does not describe the number of individuals with insufficient intake. Prevalence estimates of inadequate and excessive intake are better for informing public health applications but require multiple urine samples per person; such estimates have been generated in pediatric populations but not yet among pregnant women. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajog.2020.06.052DOI Listing

Small core needle biopsies in cytology practice: a survey of members of the American Society of Cytopathology.

J Am Soc Cytopathol 2020 Jun 18. Epub 2020 Jun 18.

Wisconsin State Laboratory of Hygiene, University of Wisconsin School of Medicine and Public Health, Department of Pathology and Laboratory Medicine, Madison, Wisconsin.

Introduction: The introduction of a new generation of core needle biopsies (CNBs) for endoscopic procedures has prompted reconsideration of the role of cytopathologists in the handling of small biopsies. The American Society of Cytopathology (ASC) has therefore conducted a survey with the intention of elucidating current practices regarding the handling of small CNBs.

Materials And Methods: The membership of the ASC was invited by email to participate in an online survey over a 2-month period. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jasc.2020.06.002DOI Listing

Endomyocardial Biopsy Characterization of Heart Failure With Preserved Ejection Fraction and Prevalence of Cardiac Amyloidosis.

JACC Heart Fail 2020 Jul 5. Epub 2020 Jul 5.

Division of Cardiology, The Johns Hopkins School of Medicine, Baltimore, Maryland. Electronic address:

Objectives: This study prospectively evaluated endomyocardial biopsies in patients with heart failure with preserved ejection fraction (HFpEF) to identify histopathologic phenotypes and their association with clinical characteristics.

Background: Myocardial tissue analysis from a prospectively defined HFpEF cohort reflecting contemporary comorbidities is lacking.

Methods: Patients with HFpEF (EF ≥50%) referred to the Johns Hopkins HFpEF Clinic between August 2014 and September 2018 were enrolled for right heart catheterization and endomyocardial biopsy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jchf.2020.04.007DOI Listing

Defining the patient acceptable symptom state for the American Orthopaedic Foot & Ankle Society score following hallux valgus surgery.

Foot Ankle Surg 2020 Jul 5. Epub 2020 Jul 5.

Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.

Background: This study aimed to define the patient acceptable symptom state (PASS) for the American Orthopaedic Foot & Ankle Society score (AOFAS) following hallux valgus surgery.

Methods: 548 patients underwent hallux valgus surgery and had AOFAS assessed preoperatively, 6 months and 2 years postoperatively. Responses to an anchor question were used as external criterion in receiver operating characteristics (ROC) analyses to define PASS thresholds. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fas.2020.06.013DOI Listing

Trading Baseline with Forelimbs Somatosensory Evoked Potential for Longitudinal Analysis in Thoracic Transection Spinal Cord Injury.

J Neurosci Methods 2020 Jul 9:108858. Epub 2020 Jul 9.

Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Traylor Building, 720 Rutland Ave., Baltimore, MD, 21205, USA; Department of Chemistry, Faculty of Science, Hong Kong Baptist University, Traylor Building, 720 Rutland Ave., Baltimore, MD, 21205, USA. Electronic address:

Patients who suffered from spinal cord injury (SCI) that come to healthcare professionals for diagnosis and treatment do not have electrophysiology baseline of somatosensory evoked potential (SSEP). The SSEP has always been used in research for data comparison to detect onset and severity of the SCI as well as for assessing its progress, endogenous and therapeutic recovery. This unmet need has motivated us to develop a new tool to substitute the baseline data with forelimb SSEP data of the same day. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jneumeth.2020.108858DOI Listing

Coexistence of idiopathic intracranial hypertension and optic disc drusen in a latin american patient: case report.

Arch Soc Esp Oftalmol 2020 Jul 8. Epub 2020 Jul 8.

Departamento de salud pública, Universidad de Caldas, Manizales, Colombia.

Optic nerve drusen are acellular concretions of calcium located in the parenchyma of the optic nerve head described as the most common cause of pseudo-papilloedema, which makes it difficult to differentiate from a true optical disc oedema. Despite it being rare optic nerve drusen and the papilloedema secondary to idiopathic intracranial hypertension can coexist in the same patient. We present a case of a 34-year-old woman referred to the Ophthalmology Department with visual discomfort, headaches, and pulsatile tinnitus of two months onset. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oftal.2020.06.017DOI Listing

The Disturbing Findings of Pediatric Firearm Injuries From the National Trauma Data Bank: 2010-2016.

J Surg Res 2020 Jul 8. Epub 2020 Jul 8.

Division of Pediatric Surgery, Department of Surgery, Children's of Alabama, University of Alabama at Birmingham, Birmingham, Alabama.

Background: Trauma is the leading cause of pediatric and adolescent morbidity and mortality. Firearm-related injuries and deaths contribute substantially to the overall disease burden. This study described the intent, location, demographics, and outcomes of a nationally representative pediatric population with firearm injuries. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jss.2020.05.096DOI Listing

Bowel wall thickening on computed tomography scan: Inter-observer agreement and correlation with endoscopic findings.

Arab J Gastroenterol 2020 Jul 8. Epub 2020 Jul 8.

Department of Diagnostic Radiology, American University of Beirut, Riad El Solh, Beirut 1107 2020, Lebanon; Department of Imaging, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA; Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:

Background And Study Aims: Bowel wall thickening (BWT) on computed tomography (CT) has been frequently reported by radiologists. There are no clear guidelines regarding the level of thickening that is correlated with definite pathology. Radiologists usually rely on their overall subjective impression, and studies on inter-observer agreement (IOA) are lacking. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajg.2020.04.012DOI Listing

Antibiotic prophylaxis for gynecologic cancer surgery.

Taiwan J Obstet Gynecol 2020 Jul;59(4):514-519

Department of Obstetrics and Gynecology, Busan Paik Hospital, Inje University, College of Medicine, South Korea; Paik Institute for Clinical Research, Inje University, College of Medicine, South Korea. Electronic address:

Objectives: The use of prophylactic antibiotics in elective gynecologic cancer surgery is essential. We aimed to establish the optimal duration of antibiotic administration to reduce the overuse of antibiotics in gynecologic cancer surgery.

Materials And Methods: We conducted a retrospective study based on the descriptive and statistical analysis of the clinical records of patients who underwent a radical hysterectomy or staging operation for gynecologic cancer between January 2014 and October 2015 at Busan Paik Hospital. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tjog.2020.05.008DOI Listing

Electroencephalogram (EEG) in COVID-19: A systematic retrospective study.

Neurophysiol Clin 2020 Jun 25. Epub 2020 Jun 25.

Université Paris Saclay-APHP, Unité de Neurophysiologie Clinique et d'Epileptologie (UNCE), Le Kremlin-Bicêtre, France; UMR BIOMAPS- CNRS, Université Paris Saclay, Inserm, CEA, 91401 Orsay, France.

Objectives: Although rare, neurological manifestations in SARS-CoV-2 infection are increasingly being reported. We conducted a retrospective systematic study to describe the electroencephalography (EEG) characteristics in this disease, looking for specific patterns.

Methods: EEGs performed in patients with positive PCR for SARS-CoV-2 between 25/03/2020 and 06/05/2020 in the University Hospital of Bicêtre were independently reviewed by two experienced neurologists. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neucli.2020.06.001DOI Listing

US withdrawal from WHO is unlawful and threatens global and US health and security.

Lancet 2020 Jul 9. Epub 2020 Jul 9.

O'Neill Institute for National and Global Health Law, Georgetown University, Washington 20001, DC, USA; Department of International Health, Georgetown University, Washington 20001, DC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(20)31527-0DOI Listing

Economic Costs and Benefits of Community-Based Lymphedema-Management Programs for Lymphatic Filariasis in India.

Am J Trop Med Hyg 2020 Jul;103(1):295-302

Department of Economics, Gettysburg College, Gettysburg, Pennsylvania.

Lymphatic filariasis (LF) is endemic in 72 countries; 15 million persons live with chronic filarial lymphedema. It can be a disabling condition, frequently painful, leading to reduced mobility, social exclusion, and depression. The Global Program to Eliminate Lymphatic Filariasis aims to stop new infections and care for affected persons, but morbidity management has been initiated in only 38 countries. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4269/ajtmh.19-0898DOI Listing

Initiating guideline-concordant gout treatment improves arterial endothelial function and reduces intercritical inflammation: a prospective observational study.

Arthritis Res Ther 2020 Jul 11;22(1):169. Epub 2020 Jul 11.

Section of Rheumatology, VA New York Harbor Health Care System, New York, NY, USA.

Background: Patients with gout have arterial dysfunction and systemic inflammation, even during intercritical episodes, which may be markers of future adverse cardiovascular outcomes. We conducted a prospective observational study to assess whether initiating guideline-concordant gout therapy with colchicine and a urate-lowering xanthine oxidase inhibitor (XOI) improves arterial function and reduces inflammation.

Methods: Thirty-eight untreated gout patients meeting American College of Rheumatology (ACR)/European League Against Rheumatism classification criteria for gout and ACR guidelines for initiating urate-lowering therapy (ULT) received colchicine (0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13075-020-02260-6DOI Listing

Intraoperative ultrasonography assistance for minimally invasive repair of the acute Achilles tendon rupture.

J Orthop Surg Res 2020 Jul 11;15(1):258. Epub 2020 Jul 11.

Department of Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250021, China.

Background: Minimally invasive repair is a better option for Achilles tendon rupture with low re-rupture and wound-related complications than conservative treatment or traditional open repair. The major problem is sural nerve injury. The purpose of this study was to evaluate the effect and advantage of the intraoperative ultrasonography assistance for minimally invasive repair of the acute Achilles tendon rupture. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13018-020-01776-6DOI Listing

Fruit and vegetable consumption is associated with lower prevalence of asymptomatic diverticulosis: a cross-sectional colonoscopy-based study.

BMC Gastroenterol 2020 Jul 11;20(1):221. Epub 2020 Jul 11.

Division of Gastroenterology, Massachusetts General Hospital, Boston, MA, USA.

Background: Previous studies of the relationship between dietary factors and risk of diverticulosis have yielded inconsistent results. We therefore sought to investigate the association between consumption of fruit and vegetables and prevalent diverticulosis.

Methods: Our study population included participants in the Gastrointestinal Disease and Endoscopy Registry (GIDER), a colonoscopy-based longitudinal cohort at the Massachusetts General Hospital, who provided comprehensive information on dietary intake and lifestyle factors using validated questionnaires prior to colonoscopy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-020-01374-0DOI Listing

Curcumin attenuates autoimmunity and renal injury in an experimental model of systemic lupus erythematosus.

Physiol Rep 2020 Jul;8(13):e14501

Department of Physiology & Biophysics, University of Mississippi Medical Center, Jackson, MS, USA.

Systemic lupus erythematosus (SLE) is an autoimmune disorder with prevalent hypertension and renal disease. To avoid side effects of immunosuppressive drugs, alternative therapies are needed. Curcumin has been used in Eastern medicine for its anti-inflammatory and antioxidant properties. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14814/phy2.14501DOI Listing

Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations.

Am J Med Genet B Neuropsychiatr Genet 2020 Jul 11. Epub 2020 Jul 11.

Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.

African Americans (AA) have lower prevalence of alcohol dependence and higher subjective response to alcohol than European Americans. Genome-wide association studies (GWAS) have identified genes/variants associated with alcohol dependence specifically in AA; however, the sample sizes are still not large enough to detect variants with small effects. Admixture mapping is an alternative way to identify alcohol dependence genes/variants that may be unique to AA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.b.32805DOI Listing

Mitochondrial division inhibitor 1 (mdivi-1) increases oxidative capacity and contractile stress generated by engineered skeletal muscle.

FASEB J 2020 Jul 11. Epub 2020 Jul 11.

Laboratory for Living Systems Engineering, Department of Biomedical Engineering, USC Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.

In skeletal muscle fibers, mitochondria are densely packed adjacent to myofibrils because adenosine triphosphate (ATP) is needed to fuel sarcomere shortening. However, despite this close physical and biochemical relationship, the effects of mitochondrial dynamics on skeletal muscle contractility are poorly understood. In this study, we analyzed the effects of Mitochondrial Division Inhibitor 1 (mdivi-1), an inhibitor of mitochondrial fission, on the structure and function of both mitochondria and myofibrils in skeletal muscle tissues engineered on micromolded gelatin hydrogels. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.201901039RRDOI Listing

Cold hardiness of the South American tomato pinworm Tuta absoluta (Lepidoptera: Gelechiidae): both larvae and adults are chill-susceptible.

Pest Manag Sci 2020 Jul 11. Epub 2020 Jul 11.

Department of Biological Sciences and Biotechnology, Botswana International University of Science and Technology, P. Bag 16, Palapye, Botswana.

Background: For many insects, including invasive species, overwintering survival is achieved behaviourally (e.g. through migration) or physiologically by entering diapause, a state of arrested physiological development that may be accompanied with depressed supercooling points (SCPs). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ps.6006DOI Listing

The Anti-Racist, Pro-patient Pledge of Emergency Medicine.

Acad Emerg Med 2020 Jul 11. Epub 2020 Jul 11.

Medical College of Wisconsin, Hub for Collaborative Medicine, 8701 W Watertown Plank Rd, Milwaukee, WI, 53226, United States.

Recognized as a specialty by the American Board of Medical Specialties over 40 years ago, emergency medicine is unique since its inception-providing care to all patients in all times of unscheduled, time-sensitive need. Members of our specialty-whether working in an academic or private practice setting-provide this care without regard to a patient's sex, sexual orientation, gender, creed, physical ability, ability to pay, or race/ethnicity. The last human determinant of health bears emphasis in our current climate of a race-based inequity crisis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acem.14081DOI Listing

Current trends in the management of acute type A aortic intramural hematoma.

J Card Surg 2020 Jul 11. Epub 2020 Jul 11.

Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.

Within the spectrum of acute aortic syndromes, intramural hematoma (IMH) is a distinct lesion that is characterized by crescentic or circumferential thickening of the aortic wall in the absence of an intimal defect. The reported incidence of IMH among all type A acute aortic syndromes ranges from 3.5% to 28. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jocs.14819DOI Listing

Cardiac Resynchronization Therapy in Patients with Atrial Fibrillation.

J Cardiovasc Electrophysiol 2020 Jul 11. Epub 2020 Jul 11.

Department of Internal Medicine, Division of Cardiology, American University of Beirut Medical Center, Beirut, Lebanon.

Atrial fibrillation (AF) is the most common cardiac arrhythmia and often occurs with heart failure (HF) [1]. AF prevalence increases with increasing severity of HF: for instance its prevalence ranges from 5 percent in patients with New York Heart Association (NYHA) functional class I HF to 40 percent in patients with NYHA class IV HF [2]. This article is protected by copyright. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jce.14665DOI Listing

Catheter Ablation of Atrial Tachycardias After Mitral Valve Surgery.

J Cardiovasc Electrophysiol 2020 Jul 11. Epub 2020 Jul 11.

Department of Internal Medicine, Division of Cardiology, American University of Beirut Medical Center, Beirut, Lebanon.

Atrial tachycardias (AT) have significant morbidity and are difficult to control with medical management alone. Structural heart diseases are known to be associated with cardiac arrhythmias. This article is protected by copyright. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jce.14667DOI Listing

Prognostic impact of tumor location in resected gallbladder cancer: A national cohort analysis.

J Surg Oncol 2020 Jul 11. Epub 2020 Jul 11.

Department of Surgery, City of Hope National Medical Center, Duarte, California.

Background And Objectives: Tumor location (peritoneal vs hepatic) has been incorporated in the 8th edition of the American Joint Committee on Cancer Staging system for gallbladder cancer. However, larger studies are needed to confirm the prognostic impact of tumor location.

Methods: Patients with pathologically-confirmed gallbladder cancer with information on primary tumor location were included from the National Cancer Database (2009-2012). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jso.26107DOI Listing

Drinking to cope with the pandemic: The unique associations of COVID-19-related perceived threat and psychological distress to drinking behaviors in American men and women.

Addict Behav 2020 Jun 27;110:106532. Epub 2020 Jun 27.

Dalhousie University, Canada.

The 2019 Coronavirus pandemic has brought about significant and unprecedented changes to the modern world, including stay-at-home orders, high rates of unemployment, and more than a hundred thousand deaths across the United States. Derived from the self-medication hypothesis, this research explored how perceived threat and psychological distress related to the COVID-19 pandemic are associated with drinking behavior among an American sample of adults. We also evaluated whether links between COVID-19-related perceived threat and psychological distress with drinking behavior are different for men and women. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.addbeh.2020.106532DOI Listing

Interventions for reducing hospital-associated deconditioning: A systematic review and meta-analysis.

Arch Gerontol Geriatr 2020 Jul 6;90:104176. Epub 2020 Jul 6.

Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, UK. Electronic address:

Purpose: To determine the effectiveness of hospital-based interventions designed to reduce Hospital-Associated Deconditioning (HAD) for people in inpatient hospital settings.

Materials & Methods: Systematic literature search of published and unpublished databases was conducted from (inception to 01 June 2020). Randomised and non-randomised controlled trials investigating the effectiveness of enhanced inpatient programmes aimed to reduce HAD in adults admitted to a hospital ward were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.archger.2020.104176DOI Listing

New record of Neosaimiri (Cebidae, Platyrrhini) from the late Middle Miocene of Peruvian Amazonia.

J Hum Evol 2020 Jul 8;146:102835. Epub 2020 Jul 8.

Laboratoire de Paléontologie, Institut des Sciences de l'Évolution de Montpellier (ISE-M, UMR 5554, CNRS/UM/IRD/EPHE), Université de Montpellier, c.c. 064, Place Eugène Bataillon, Montpellier Cedex 05, F-34095, France. Electronic address:

The Honda Group of La Venta, Colombia, has yielded a wide array of crown platyrrhine primates, documenting the late Middle Miocene epoch (ca. 13.1-12. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhevol.2020.102835DOI Listing

"Clinical Characteristics, Outcomes and Prognosticators in Adult Patients Hospitalized with COVID-19".

Am J Infect Control 2020 Jul 8. Epub 2020 Jul 8.

IU Health Physicians Inpatient Medicine, IU School of Medicine Division of General Internal Medicine and Geriatrics, Assistant Professor of Clinical Medicine, 1801 N Senate Boulevard, Noyes Pavilion E-140, Indianapolis, IN 46202. Electronic address:

Background: COVID-19 is a novel disease caused by SARS-CoV-2.

Methods: We conducted a retrospective evaluation of patients admitted with COVID-19 to one site in March 2020. Patients were stratified into three groups: survivors who did not receive mechanical ventilation (MV), survivors who received MV and those who received MV and died during hospitalization. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajic.2020.07.005DOI Listing

Exposure to environmentally-relevant concentrations of hexavalent chromium does not induce ovarian toxicity in mice.

Regul Toxicol Pharmacol 2020 Jul 8:104729. Epub 2020 Jul 8.

ToxStrategies Inc., Katy, TX, 77494, USA.

Exposure to high concentrations of hexavalent chromium [Cr(VI)] in drinking water (≥250 ppm) is reported to decrease ovarian follicle counts and increase follicular atresia in mice. To assess effects at lower concentrations, herein we exposed B6C3F1 mice to 0.1-150 ppm Cr(VI) in drinking water for 90 days in a GLP-compliant study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yrtph.2020.104729DOI Listing

Evolutionary biogeography of the reef-building coral genus Galaxea across the Indo-Pacific ocean.

Mol Phylogenet Evol 2020 Jul 8:106905. Epub 2020 Jul 8.

Marine Biophysics Unit, Okinawa Institute of Science and Technology, 1919-1 Tancha, Onna-son, Okinawa, 904-0495, Japan.

Stony corals (Scleractinia) form the basis for some of the most diverse ecosytems on Earth, but we have much to learn about their evolutionary history and systematic relationships. In order to improve our understanding of species in corals we here investigated phylogenetic relationships between morphologically defined species and genetic lineages in the genus Galaxea (Euphyllidae) using a combined phylogenomic and phylogeographic approach. Previous studies revealed the nominal species G. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ympev.2020.106905DOI Listing
July 2020
3.916 Impact Factor