448 results match your criteria American journal of ophthalmology case reports[Journal]


Characterization of Blau syndrome panuveitis with wide-field fluorescein angiography.

Am J Ophthalmol Case Rep 2019 Jun 29;14:92-94. Epub 2019 Mar 29.

Department of Ophthalmology, Wake Forest School of Medicine, Winston-Salem, NC, USA.

Purpose: To describe a case of Blau panuveitis, characterized on both portable and tabletop wide-field fluorescein angiography, which resolved on systemic immunosuppression.

Observations: A 5-year-old female presented with bilateral eye pain, redness, and decreased visual acuity due to panuveitis and had a history of arthritis, tenosynovitis, and dermatitis. Similar ocular and systemic findings in the patient's mother and maternal half-brother prompted genetic testing that confirmed the diagnosis of the rare Blau syndrome. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183023
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http://dx.doi.org/10.1016/j.ajoc.2019.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447728PMC
June 2019
2 Reads

Cyclosporine and prednisolone combination therapy as a potential therapeutic strategy for relentless placoid chorioretinitis.

Am J Ophthalmol Case Rep 2019 Jun 23;14:87-91. Epub 2019 Mar 23.

Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Purpose: Relentless placoid chorioretinitis (RPC) is a new disease concept that was proposed by Jones et al. in 2000. Some cases of RPC have been reported; however, a treatment strategy has not yet been established. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444293PMC

Isolated rod dysfunction associated with a novel genotype of .

Am J Ophthalmol Case Rep 2019 Jun 19;14:83-86. Epub 2019 Mar 19.

UCL Institute of Ophthalmology, University College London, London, UK.

Purpose: To describe the clinical and electrophysiological features of an unusual retinopathy in a patient with a novel genotype of , mutations in which are implicated in autosomal recessive retinitis pigmentosa (rod-cone dystrophy).

Observations: A 61-year old asymptomatic woman was referred to the inherited retinal disorders clinic because of peripheral retinal pigmentary changes. She had normal visual acuity and color vision. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183032
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http://dx.doi.org/10.1016/j.ajoc.2019.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438912PMC
June 2019
1 Read

Rapid displacement of subretinal hemorrhage from a choroidal neovascular membrane with intravitreal C3F8 gas and face-down positioning.

Am J Ophthalmol Case Rep 2019 Jun 14;14:79-82. Epub 2019 Mar 14.

Retina Consultants of Orange County, Fullerton, CA, USA.

Purpose: To describe a case of rapid displacement of subretinal hemorrhage (SRH) from a choroidal neovascular membrane (CNV) with intravitreal injection of C3F8 gas.

Observations: A 66-year-old patient presented in clinic with count fingers (CF) vision from a fibrovascular scar in the right eye (OD) and 20/30 vision in the left eye (OS) with butterfly dystrophy. His left eye developed a CNV and was managed with monthly intravitreal anti-VEGF agents for 29 months. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428934PMC
June 2019
4 Reads

Familial retinal arteriolar tortuosity and quantification of vascular tortuosity using swept-source optical coherence tomography angiography.

Am J Ophthalmol Case Rep 2019 Jun 7;14:74-78. Epub 2019 Mar 7.

University of Washington Department of Ophthalmology 325 Ninth Avenue, Box 359608, Seattle, WA, 98104, USA.

Purpose: Familial retinal arteriolar tortuosity (FRAT) is a rare autosomal dominant disorder that is characterized by tortuosity of the second and higher order retinal arterioles. We implement swept-source optical coherence tomography angiography (SS-OCTA) to quantify vessel tortuosity in patients with FRAT. We hypothesize that patients with FRAT will have higher retinal arteriole tortuosity when compared to controls. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425085PMC

Acute syphilitic posterior placoid chorioretinopathy: An infectious or autoimmune disease?

Am J Ophthalmol Case Rep 2019 Jun 8;14:70-73. Epub 2019 Mar 8.

Department of Ophthalmology, Hospital Universitario Austral, Argentina.

Purpose: To report a case of acute syphilitic posterior placoid chorioretinopathy (ASPPC) that demonstrated partial resolution with immunosuppressive therapy secondary to a misdiagnosis as Behçet's disease followed by a relapse which was successfully treated with the appropriate treatment.

Observations: A 34-year-old female patient presented to our service with complaints of decreased vision in the left eye (OS). She initially developed similar symptoms seven months prior to presentation and was diagnosed as Behçet's disease based on the clinical picture of papillitis, vasculitis and placoid chorioretinitis in the posterior pole of OS. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423698PMC
June 2019
1 Read

A unique case of chronic myeloid leukemia presenting as monocular vision loss with unilateral retinopathy.

Am J Ophthalmol Case Rep 2019 Jun 15;14:67-69. Epub 2019 Feb 15.

West Virginia University School of Medicine, 1 Medical Center Dr, Morgantown, WV, USA.

Purpose: To report a case of unilateral leukemic retinopathy secondary to chronic myeloid leukemia (CML).

Observations: Patient presented to clinic with a visual acuity (VA) of 20/200 in the right eye (OD) after several months of progressive monocular vision loss and was found to have dense pre-retinal hemorrhage. Patient underwent 23-gauge pars plana vitrectomy to clear the preretinal hemorrhage along with a complex macula-off retinal detachment repair to address retinal tear and multilayer retinal hemorrhage. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416657PMC

Late onset corneal haze after corneal cross-linking for progressive keratoconus.

Am J Ophthalmol Case Rep 2019 Jun 26;14:64-66. Epub 2019 Feb 26.

Ophthalmiatrion Athinon, Sina 2, 10672, Athens, Greece.

Purpose: To present the case of a patient that underwent corneal crosslinking for progressive keratoconus and 18 months later revealed clinically significant corneal stromal haze.

Observations: A 20-year-old male presented with progressive visual loss OU for the past few years. His corrected distance visual acuity (CDVA) OD was 20/30 (-2. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411486PMC
June 2019
1 Read

Focal vitreomacular traction: Resolution after ocular massage.

Am J Ophthalmol Case Rep 2019 Jun 22;14:61-63. Epub 2019 Feb 22.

Department of Ophthalmology, General University Hospital Morales Meseguer, Murcia, Spain.

Purpose: Vitreomacular traction (VMT) is a relatively common ocular disorder that may distort the foveal structure causing visual symptoms. The influence of ocular massage (OM) on this condition has not been considered yet. We aim to report clinical and OCT features of VMT release associated with OM. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407139PMC

Isolated conjunctival granuloma as a first manifestation of Parinaud's oculoglandular syndrome: A case report.

Am J Ophthalmol Case Rep 2019 Jun 23;14:58-60. Epub 2019 Feb 23.

Centro de la Visión Filial Clínica las Condes, Santiago, Chile.

Purpose: Parinaud's oculo-glandular syndrome (POGS) is the most frequent manifestation of ocular bartonellosis, and usually presents with local lymphadenopathies and systemic symptoms. We present a case of isolated conjunctival granuloma as the sole manifestation of ocular bartonellosis.

Observations: A 67-year-old female presented to the authors' eye clinic with complaints of a 2-week history of unilateral red eye and chemosis. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402948PMC
June 2019
1 Read

Presumed choroidal metastasis from soft tissue myoepithelial carcinoma.

Am J Ophthalmol Case Rep 2019 Jun 22;14:55-57. Epub 2019 Feb 22.

Save Sight Institute, University of Sydney, Sydney, New South Wales, Australia.

Purpose: To report a case of presumed choroidal metastasis from soft tissue myoepithelial carcinoma and highlight challenges in its diagnosis.

Observations: A 52-year-old man was referred with a two-week history of photopsia in his left eye. His background medical history included known soft tissue myoepithelial carcinoma metastatic to his bone, lung, liver and chest wall. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402231PMC
June 2019
1 Read

Unilateral serous retinal detachment with choroidal thickening as a first presenting sign of acute myeloid leukemia.

Am J Ophthalmol Case Rep 2019 Jun 23;14:51-54. Epub 2019 Feb 23.

Department of Ophthalmology and Visual Science, Kochi Medical School, Kochi University, Nankoku City, Kochi, Japan.

Purpose: Serous retinal detachment is rare in leukemia, but bilateral or unilateral cases have been reported as the presenting sign of acute leukemia or the first sign of relapsing leukemia. We here report a case of unilateral serous retinal detachment with choroidal thickening before the detection of atypical lymphocytes or myeloblasts as the initial manifestation of subsequently diagnosed acute myeloid leukemia.

Observations: A 43-year-old woman presented with serous retinal detachment in her left eye. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396195PMC
June 2019
9 Reads

Concurrent acute retinal necrosis and orbital inflammation: Report of 2 cases.

Am J Ophthalmol Case Rep 2019 Jun 13;14:47-50. Epub 2019 Feb 13.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.

Purpose: To describe the rare entity of concurrent herpetic acute retinal necrosis (ARN) and orbital inflammation.

Observations: Two cases of ARN with simultaneous orbital inflammation are described. A 40-year old male presented with a painful left eye and hand motion visual acuity (VA). Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393694PMC
June 2019
1 Read

Traumatic chorioretinitis sclopetaria: Risk factors, management, and prognosis.

Am J Ophthalmol Case Rep 2019 Jun 16;14:39-46. Epub 2019 Feb 16.

Byers Eye Institute, Department of Ophthalmology, Stanford University, Palo Alto, CA, USA.

Purpose: To describe new cases of sclopetaria and evaluate the risk factors, management, and visual prognosis of all reported cases in the literature.

Observations: We performed a retrospective, observational case series. This study included six cases (median age 23, interquartile range 33) of sclopetaria. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183035
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http://dx.doi.org/10.1016/j.ajoc.2019.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384308PMC
June 2019
11 Reads

Resolution of pain with periocular injections in a patient with a 7-year history of chronic ocular pain.

Am J Ophthalmol Case Rep 2019 Jun 12;14:35-38. Epub 2019 Feb 12.

Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami, 900 NW 17th Street, Miami, FL, 33136, USA.

Purpose: We report a case of a male patient with chronic ocular pain that resolved completely following peripheral nerve blocks.

Observations: A 66-year-old male presented with a seven-year history of severe left eye pain and photophobia. The pain began after retinal detachment repair with scleral buckle placement. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378870PMC
June 2019
1 Read

Corneal endothelial damage after simultaneous PRK and corneal cross-linking in stable keratoconus.

Am J Ophthalmol Case Rep 2019 Jun 12;14:32-34. Epub 2019 Feb 12.

Studio Italiano di Oftalmologia, Italy.

Purpose: To describe a case of endothelial damage after photorefractive keratectomy (PRK) combined with corneal cross-linking (CXL).

Observations: A 34-year-old man with diagnosis of stable keratoconus presented at our clinic complaining of vision loss in the left eye after same-day simultaneous PRK and CXL. One year postoperatively, slit-lamp examination showed central corneal haze and specular microscopy demonstrated reduced endothelial cell density compared with the preoperative state. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378891PMC

Long-term results of surgical excision of conjunctival retention cyst using trypan blue with methylcellulose.

Am J Ophthalmol Case Rep 2019 Jun 6;14:28-31. Epub 2019 Feb 6.

Department of Ophthalmology, Stein Eye Institute, UCLA, Los Angeles, CA, USA.

Purpose: Conjunctival retention cysts may recur if not completely removed. However, the cyst wall often ruptures during surgical excision, making complete removal difficult. In order to ensure complete cyst excision, we used a method of staining the inner cyst wall using trypan blue augmented by Methyl cellulose. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377388PMC

Corneal ulceration associated with Nivolumab use.

Am J Ophthalmol Case Rep 2019 Jun 7;14:26-27. Epub 2019 Feb 7.

Parker Cornea, 1720 University Blvd Suite 503, Birmingham, AL, 35233, USA.

Purpose: To describe a case of corneal ulceration associated with Nivolumab use.

Observations: An 80-year-old woman treated with Nivolumab for metastatic melanoma developed an intractable corneal ulcer in her left eye, refractory to all therapies - including surgery to cover the ulcer with a conjunctival flap - until topical prednisolone acetate was tried, which was curative.

Conclusions And Importance: Nivolumab use may be associated with a form of steroid-responsive corneal ulceration. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377387PMC

Alendronate induced chorioretinitis: The importance of meticulous assessments.

Am J Ophthalmol Case Rep 2019 Jun 9;14:21-25. Epub 2019 Jan 9.

Byers Eye Institute, Stanford University, Palo Alto, CA, USA.

Purpose: To report a case of presumed bilateral chorioretinitis secondary to alendronate therapy.

Observations: A 71-year-old female presented to the clinic in July 2017 with six months history of difficulty in reading along with floaters in both eyes which were more severe in the right eye. Past medical and surgical history revealed a history of hypertension, gout, hyperthyroidism, osteoporosis, and humerus fracture. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374782PMC
June 2019
1 Read

Repeated ophthalmic self-penetration with defecated needles.

Am J Ophthalmol Case Rep 2019 Jun 5;14:19-20. Epub 2019 Feb 5.

Vanderbilt Eye Institute, Department of Ophthalmology & Visual Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1016/j.ajoc.2019.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373204PMC
June 2019
7 Reads

Are iris mammillations correlated with keratoconus?

Am J Ophthalmol Case Rep 2019 Jun 2;14:16-18. Epub 2019 Feb 2.

Department of Ophthalmology, Otorhinolaryngology, and Head and Neck Surgery, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.

Purpose: To describe the presence of iris mammillations (IM) in keratoconus.

Design: Retrospective case series and literature review.

Observations: This is a retrospective case series of eight patients presenting with keratoconus and IM, who were examined between January 2016 and December 2017 in the ophthalmology outpatient clinic. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370584PMC

Floppy eyelid syndrome in stickler syndrome.

Am J Ophthalmol Case Rep 2019 Jun 31;14:14-15. Epub 2019 Jan 31.

Department of Ophthalmology, Mayo Clinic, 200 First Street, SW, Rochester, MN, 55905, USA.

Purpose: To report the possible connection between Stickler syndrome and floppy eyelid syndrome.

Observations: A 36-year-old man with genetically confirmed Stickler syndrome presented with prominent bilateral eyelid laxity consistent with floppy eyelid syndrome. He had a high-arched palate and reported years of apneic episodes during sleep consistent with obstructive sleep apnea (OSA). Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365810PMC
June 2019
1 Read

Occipital tip injury with homonymous central scotoma: OCT-NFL and RGC correlation.

Am J Ophthalmol Case Rep 2019 Jun 26;14:10-13. Epub 2019 Jan 26.

Department of Ophthalmology and Visual Sciences, Montefiore Medical Center, Albert Einstein School of Medicine, 3400 Bainbridge Avenue, Bronx, NY, United States.

Purpose: To report one case of homonymous paracentral scotoma with corresponding optical coherence tomography (OCT) findings in a young woman after injury to the left occipital lobe tip.

Observations: A young woman with past medical history of Hodgkin's lymphoma and large B-cell lymphoma metastatic to the left occipital lobe status post resection presented to the eye clinic with a chief complaint of a "blind spot" in the right eye since her surgery. Humphrey visual field (HVF) showed a right homonymous paracentral scotoma corresponding to the non-decussating and decussating optic radiation for central vision originating from the left lateral geniculate nucleus (LGN). Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360247PMC
June 2019
1 Read

Microcornea, posterior megalolenticonus, persistent fetal vasculature, chorioretinal coloboma (MPPC) syndrome: Case series post vitrectomy.

Am J Ophthalmol Case Rep 2019 Jun 25;14:5-9. Epub 2019 Jan 25.

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th St, Miami, FL, United States.

Purpose: MPPC syndrome has been described as a syndrome that presents with chorioretinal coloboma, posterior megalolenticonus, persistent fetal vasculature, and chorioretinal coloboma. The purpose of our study is to report three patients who present with a variation of MPPC syndrome who each underwent pars plana vitrectomy, pars plana lensectomy, and amblyopic management. Clinical characteristics, ancillary test findings, and post-surgical functional results are compared to what is reported in the literature. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360246PMC

Effective treatment of refractory sympathetic ophthalmia with glaucoma using adalimumab.

Am J Ophthalmol Case Rep 2019 Jun 25;14:1-4. Epub 2019 Jan 25.

Department of Ophthalmology and Visual Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima City, Hiroshima, 734-8551, Japan.

Purpose: Sympathetic ophthalmia (SO) is an autoimmune, bilateral, granulomatous panuveitis, which occurs following penetrating eye injury or eye surgery. We report two cases of refractory SO in patients with a history of trabeculectomy, which were treated effectively with adalimumab.

Observations: Case 1: A 69-year-old male with a history of trabeculectomy for rubeotic glaucoma of the right eye, secondary to diabetic retinopathy 8 years prior, presented with a decrease in visual acuity of the left eye due to SO. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360245PMC
June 2019
4 Reads

Delayed spontaneous closure of blue laser-induced full thickness macular hole.

Am J Ophthalmol Case Rep 2019 Mar 9;13:154-156. Epub 2019 Jan 9.

Lebanese American University, Beirut, Lebanon.

Purpose: To report a blue laser-induced full thickness macular hole (FTMH) with delayed spontaneous closure without surgical intervention.

Observations: A 14-year old male developed full thickness macular hole after momentary exposure to a high-power handheld blue laser device. The macular hole closed spontaneously over a long period of observation. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351355PMC
March 2019
1 Read

Late detachment of Descemet's membrane after penetrating keratoplasty for pellucid marginal degeneration.

Am J Ophthalmol Case Rep 2019 Mar 18;13:151-153. Epub 2018 Dec 18.

Department of Ophthalmology & Visual Sciences, University of Illinois College of Medicine, 1855 W Taylor Street, Chicago, IL 60612, USA.

Purpose: we report a case of late spontaneous large detachment of Descemet's membrane in recurrent pellucid marginal degeneration after penetrating keratoplasty.

Observations: a 73-year-old man presented to clinic with spontaneous detachment of his Descemet's membrane 30 years after penetrating keratoplasty for pellucid marginal degeneration. Efforts were made to bubble the membrane back into place without success. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350212PMC

Massive orbital myiasis arising from nasal myiasis in an Indonesian patient with diabetes.

Am J Ophthalmol Case Rep 2019 Mar 9;13:147-150. Epub 2019 Jan 9.

Department of Parasitology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.

Purpose: Orbital myiasis is a rare condition. We report a case of massive orbital myiasis (ophthalmomyiasis profunda) arising from nasal myiasis and caused by in a patient with diabetes.

Observations: A 55-year-old woman presented with massive orbital myiasis from larvae invading the entire orbit, with only a small part of sclera and bulbar conjunctiva left of the ocular structures left unaffected. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348767PMC

Spontaneous resolution of myopic foveoschisis and a macular hole with retinal detachment.

Am J Ophthalmol Case Rep 2019 Mar 9;13:143-146. Epub 2019 Jan 9.

Miyata Eye Hospital, 6-3, Kuraharacho, Miyakonojo, Miyazaki, 885-0051, Japan.

Purpose: The aim of this report was to describe a case of myopic foveoschisis and a macular hole with retinal detachment that resolved spontaneously.

Observations: A 62-year-old woman with bilateral blurred vision was referred to our department. Her best-corrected visual acuity (BCVA) was 0. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348488PMC

Diffuse lamellar keratitis after epi-off corneal crosslinking: An under-recognized complication?

Am J Ophthalmol Case Rep 2019 Mar 9;13:140-142. Epub 2019 Jan 9.

The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, United States.

Purpose: To report diffuse lamellar keratitis (DLK) occurring in an eye that underwent epithelium-off (epi-off) corneal cross-linking (CXL) as a treatment for post-surgical ectasia and the successful treatment of progressive ectasia with a novel epi-on CXL and conductive keratoplasty (CK) treatment.

Observations: A 42-year-old man presented with corneal ectasia in his right eye 3 years after laser in situ keratomileusis (LASIK) surgery. He underwent epi-off corneal CXL using the Dresden protocol. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348932PMC

Mixed cranial neuropathies due to occult perineural invasion of basal cell carcinoma.

Am J Ophthalmol Case Rep 2019 Mar 19;13:136-139. Epub 2018 Dec 19.

Department of Ophthalmology, University of California, San Francisco, 10 Koret Way, San Francisco, CA, 94143, USA.

Purpose: To report a diagnostically challenging case of cranial neuropathy due to perineural invasion by a basal cell carcinoma presenting 7.5 years after treatment of the primary tumor with Mohs micrographic surgery.

Observations: A 62-year-old male with a history of Mohs micrographic surgery for basal cell carcinoma (BCC) of the left brow presented with insidious onset of diplopia and paresthesia localizing to the ipsilateral cranial nerves V, V, and VI. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183013
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http://dx.doi.org/10.1016/j.ajoc.2018.12.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348452PMC
March 2019
2 Reads

Hypertensive choroidopathy: Multimodal imaging and the contribution of wide-field swept-source oct-angiography.

Am J Ophthalmol Case Rep 2019 Mar 9;13:131-135. Epub 2019 Jan 9.

Department of Ophthalmology, Croix-Rousse University Hospital, Hospices Civils de Lyon, Lyon, France.

Purpose: To present the case of a patient with a hypertensive choroidopathy and her follow-up using multimodal imaging; and to assess how wide-field swept-source (SS) Optical Coherence Tomography Angiography (OCTA) contributes to detecting the areas of hypoperfusion.

Observations: A 25-year-old white woman with terminal renal insufficiency, myopericarditis, and cerebrospinal fluid pressure of 37 mmHg indicating intracranial hypertension, presented with a painless loss of vision in both eyes. Her blood pressure was 190/135 mmHg. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348489PMC
March 2019
2 Reads

Endophthalmitis following cataract surgery and intracameral antibiotic: Moxifloxacin resistant .

Am J Ophthalmol Case Rep 2019 Mar 8;13:127-130. Epub 2018 Dec 8.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller, School of Medicine, Miami, FL, USA.

Purpose: To describe an immunosuppressed patient who developed acute-onset postoperative endophthalmitis caused by a moxifloxacin-resistant strain of after cataract surgery despite the use of intracameral moxifloxacin.

Observations: A 76-year old woman with a history of birdshot chorioretinopathy controlled on systemic immunosuppression underwent uneventful cataract surgery in her right eye. Compounded intracameral moxifloxacin 0. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325070PMC
March 2019
13 Reads

Bilateral papillitis and vitritis as the initial ophthalmologic finding in a patient with complex medical history, leading to diagnosis of multisystem sarcoidosis.

Am J Ophthalmol Case Rep 2019 Mar 21;13:122-126. Epub 2018 Dec 21.

Massachusetts Eye Research and Surgery Institution (MERSI), 1440 Main Street, Suite 201, Waltham, MA, 02451, USA.

Aim: To report a case of bilateral papillitis as the initial ophthalmologic presentation in a patient with complex medical history and multisystemic symptoms, eventually revealing a diagnosis of sarcoidosis.

Methods: Retrospective interventional case report.

Report: A 54-year-old Caucasian woman presented with bilateral decreased vision, photophobia and eye pain for a month. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183024
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http://dx.doi.org/10.1016/j.ajoc.2018.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322055PMC
March 2019
14 Reads

Nodular fasciitis: A rapidly enlarging destructive periorbital mass in an infant.

Am J Ophthalmol Case Rep 2019 Mar 19;13:119-121. Epub 2018 Apr 19.

Department of Ophthalmology and Visual Sciences, The University of British Columbia, Vancouver, Canada.

Purpose: To review the clinical and histopathological features of nodular fasciitis, a rare benign periorbital tumor that mimics orbital malignancy, by presenting a case involving an infant with marked orbital wall erosion requiring repair.

Observations: A 9-month-old boy developed a rapidly growing periorbital mass concerning for a soft tissue malignancy. Computerized tomography (CT) scans showed bony erosion of the lateral orbital wall. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312801PMC

Daratumumab-induced transient myopic shift.

Am J Ophthalmol Case Rep 2019 Mar 18;13:116-118. Epub 2018 Dec 18.

Department of Ophthalmology, Mount Sinai Medical Center, 1468 Madison Ave, New York, NY, 10029, USA.

Purpose: To describe an unprecedented case of transient myopic shift induced by a chemotherapeutic agent, daratumumab.

Observations: A 43-year-old emmetropic female with multiple myeloma experienced sudden onset of myopic shift during her first intravenous dose of daratumumab, an increasingly common FDA-approved chemotherapeutic agent. Her myopia was corrected with -4D lenses in both eyes, and the patient reports cessation of symptoms and disuse of lenses after two days. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183017
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http://dx.doi.org/10.1016/j.ajoc.2018.12.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312830PMC
March 2019
4 Reads

Clinical findings of end-stage retinitis pigmentosa with a homozygous variant (p.R653X).

Am J Ophthalmol Case Rep 2019 Mar 19;13:110-115. Epub 2018 Dec 19.

Department of Ophthalmology, The Jikei University School of Medicine, Tokyo, Japan.

Purpose: To report clinical and genetic features of a Japanese patient with end-stage retinitis pigmentosa (RP) caused by a homozygous variant.

Methods: We performed comprehensive ophthalmic examinations. Whole exome sequencing analysis was used to investigate the RP patient with parental consanguinity. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.12.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307093PMC
March 2019
1 Read

Glaucomatous optic disc changes despite normal baseline intraocular pressure in a child.

Am J Ophthalmol Case Rep 2019 Mar 14;13:104-109. Epub 2018 Dec 14.

Bascom Palmer Eye Institute, The University of Miami Miller School of Medicine, 900 NW 17th Street 450N, Miami, FL, 33136, USA.

Purpose: We describe a case of normal tension glaucoma in the setting of sickle cell disease in a 9-year-old patient with a five-year follow up.

Observations: A 9-year-old male patient with a history of sickle cell disease presented initially at the age of 4 years for evaluation of a brief episode of nonspecific eye pain that had spontaneously resolved prior to the clinic visit. Over the course of several years, the patient was noted to have progressive optic disc cupping bilaterally, retinal nerve fiber layer thinning bilaterally, and has developed a corresponding inferior arcuate defect on automated visual field testing in the right eye, all without elevated intraocular pressures (IOP). Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307040PMC

Ocular pigmentary changes associated with chronic minocycline use.

Am J Ophthalmol Case Rep 2019 Mar 11;13:102-103. Epub 2018 Dec 11.

New York University Department of Ophthalmology, USA.

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http://dx.doi.org/10.1016/j.ajoc.2018.12.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305682PMC

Erotic asphyxiation: May have you seeing double.

Am J Ophthalmol Case Rep 2019 Mar 19;13:99-101. Epub 2018 Dec 19.

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.

Purpose: If not recognized and treated promptly, nontraumatic orbital subperiosteal hemorrhage (NTSOH) can have serious sequelae including compressive optic neuropathy and permanent vision loss. The following case establishes erotic asphyxiation as a cause of NTSOH.

Observations: A 29 year-old patient presented with diplopia and periorbital edema and ecchymosis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183021
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http://dx.doi.org/10.1016/j.ajoc.2018.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305683PMC
March 2019
1 Read

Urrets-Zavalia syndrome with interface fluid syndrome following laser in situ keratomileusis.

Am J Ophthalmol Case Rep 2019 Mar 18;13:96-98. Epub 2018 Dec 18.

Cornea and External Disease Department, Moorfields Eye Hospital NHS Foundation Trust, 162 City Road, EC1V 2PD, London, UK.

Purpose: We describe the case of a 41-year-old male that underwent laser in situ keratomileusis (LASIK) complicated by Urrets-Zavalia syndrome with interface fluid syndrome and epithelial ingrowth.

Observation: The patient presented at our institution with headache and blurred vision three weeks after a right microkeratome-assisted LASIK procedure. On examination, the visual acuity was hand movements and the intraocular pressure (IOP) was 45 mmHg with fluid in the flap interface, a fixed pupil in moderate mydriasis, iris transillumination and cells in the anterior chamber. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183030
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http://dx.doi.org/10.1016/j.ajoc.2018.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305690PMC
March 2019
10 Reads

Topical steroids: A non-surgical approach for recurrent macular holes.

Am J Ophthalmol Case Rep 2019 Mar 18;13:93-95. Epub 2018 Dec 18.

Department of Ophthalmology, University of Toronto, St. Michael's Hospital, Toronto, Canada.

Purpose: Report a case of a recurrent macular hole which completely resolved with a non-surgical approach with steroid drops.

Observations: While traction is considered the mayor contributor to full thickness macular hole formation, retinal hydration as that in cystoid macular edema also plays an important role.

Conclusions And Importance: Topical corticosteroid drops can be considered as an alternative therapy for small recurrent macular holes that lack tractional components and have an appearance of cystoid changes on the edges of the hole. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305691PMC

Iris melanoma relapsing sixteen years after proton-beam therapy: The importance of lifelong follow-up.

Am J Ophthalmol Case Rep 2019 Mar 6;13:89-92. Epub 2018 Dec 6.

Institut Curie, PSL Research University, Department of Ophthalmology, F-75005, Paris, France.

Purpose: To report a case of locally recurrent spindle-cell iris amelanotic melanoma 16 years after proton-beam therapy.

Observations: In 2001, a 45-year-old man presented with an amelanotic iris melanoma, extending from the 5 to 10 o'clock positions on his left eye. High-frequency ultrasonography showed extension of melanoma into the ciliary body. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305799PMC
March 2019
1 Read

Characterization of corneal deposition keratopathy in the setting of blood cell dyscrasia and a minimally invasive technique to clear the cornea in a single case.

Am J Ophthalmol Case Rep 2019 Mar 11;13:83-88. Epub 2018 Dec 11.

Oregon Health & Science University, Department of Ophthalmology (Casey Eye Institute), 3375 SW Terwilliger Blvd, Portland, OR, 97239, USA.

Purpose: To report 3 cases of corneal protein deposition occurring in association with systemic disease, with one case demonstrating a novel technique for clearing corneal deposits.

Observations: Three patients presented with corneal deposits associated with systemic disease. Corneal involvement was noted prior to diagnosis of systemic disease in two patients, leading to subsequent diagnosis of multiple myeloma or monoclonal gammopathy of undetermined significance. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302133PMC
March 2019
2 Reads

Manifestation of a solitary retinal astrocytic hamartoma in a patient with Best macular dystrophy.

Am J Ophthalmol Case Rep 2019 Mar 11;13:80-82. Epub 2018 Dec 11.

Casey Eye Institute at Oregon Health & Science University, United States.

Purpose: To report the case of an adolescent male with a history of Best macular dystrophy and retinal astrocytic hamartoma.

Observations: A 15 year old male with a history of Best macular dystrophy who had been followed by ophthalmology for 9 years was noted to have progressive enlargement of a superonasal peripapillary retinal lesion. Imaging and exam are consistent with a diagnosis of retinal astrocytic hamartoma. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183033
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http://dx.doi.org/10.1016/j.ajoc.2018.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299127PMC
March 2019
11 Reads

Homonymous quadrantic macular ganglion cell complex loss as a sign of trans-synaptic degeneration from occipital lobe lesion.

Am J Ophthalmol Case Rep 2019 Mar 12;13:76-79. Epub 2018 Dec 12.

Division of Ophthalmology, University of São Paulo Medical School, São Paulo, Brazil.

Purpose: to describe a patient with visual field (VF) defect from an occipital lobe lesion that was found to have macular ganglion cells complex (GCC) quadrantic reduction without significant peripapillary retinal nerve fiber layer (RNFL) loss on optical coherence tomography (OCT). To emphasize that macular GCC loss may be the major ocular manifestation of trans-synaptic optic pathway degeneration in occipital lobe lesions.

Observations: A 15-year-old female was investigated after a VF examination revealed a right homonymous inferior quadrantanopia. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299126PMC
March 2019
1 Read

Coenzyme Q10 treatment improved visual field after homonymous quadrantanopia caused by occipital lobe infarction.

Am J Ophthalmol Case Rep 2019 Mar 9;13:70-75. Epub 2018 Dec 9.

Instituto Oftalmológico Fernández-Vega, Avenida Doctores Fernández-Vega, 34, 33012, Oviedo, Spain.

Purpose: To report the clinical findings and management of a case of occipital lobe infarction with homonymous quadrantanopia in a patient treated with vitamins and coenzyme Q10.

Observations: A currently 69-years-old patient presenting in 2007 left inferior quadrantanopia following a right occipital lobe stroke with initial visual field index of 82% and 79% in the right and left eyes, respectively. From 2007 to 2010 was treated with vitamin and antioxidant complexes, without specific signs of changes observed in the visual field (81% right eye, 79% left eye). Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296271PMC

Optical coherence tomography and video recording of a case of bilateral contractile peripapillary staphyloma.

Am J Ophthalmol Case Rep 2019 Mar 5;13:66-69. Epub 2018 Dec 5.

Department of Ophthalmology and Laboratory for Visual Science, National Center for Child Health and Development, Tokyo, Japan.

Purpose: To report a case of bilateral contractile peripapillary staphyloma (CPS) examined by optical coherence tomography (OCT) and video recording.

Observation: We report the clinical history of a male infant with bilateral CPS. Two ophthalmic examinations under general anesthesia were performed during follow-up examinations. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296270PMC

Three cases of acute sterile corneal melt after cataract surgery.

Am J Ophthalmol Case Rep 2019 Mar 4;13:62-65. Epub 2018 Dec 4.

Department of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, Nagasaki, 852-8501, Japan.

Purpose: To report three cases of acute sterile corneal melt after cataract surgery.

Observations: Case 1 was a 21-year-old male presenting with a corneal perforation of his right eye at 10 days after cataract surgery. Case 2 was a 67-year-old male who developed a corneal melt in his left eye at 15 days after cataract surgery. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297052PMC
March 2019
1 Read

Spontaneous closure of a chronic full thickness macular hole after failed surgery.

Am J Ophthalmol Case Rep 2019 Mar 5;13:59-61. Epub 2018 Dec 5.

Retina Service, Department of Ophthalmology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

Purpose: To describe an unusual case of spontaneous closure of a chronic, large, idiopathic, stage 4 macular hole after failed surgery.

Observations: A 75-year-old female presented with a history of a chronic, full thickness macular hole after failed surgery in the right eye. Two years after onset, she developed a fibrotic scar, which closed the macular hole and unexpectedly improved her vision. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292999PMC