767 results match your criteria American journal of ophthalmology case reports[Journal]


Vogt-Koyanagi-Harada disease presenting secondary to a post-infectious autoimmune response.

Am J Ophthalmol Case Rep 2020 Sep 22;19:100793. Epub 2020 Jun 22.

Department of Ophthalmology, Brooke Army Medical Center, San Antonio, TX, USA.

Purpose: To report a rare case of Vogt-Koyanagi-Harada disease likely secondary to post-infectious autoimmune response in a 14-year-old Hispanic female.

Observations: On presentation, visual acuity was 20/400 in the right eye and 20/20 in the left eye. The patient also had bilateral hyperemia, subretinal fluid, and vitreous cell graded at 1+. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320312PMC
September 2020

Concurrent primary Sjögren's syndrome and isolated ocular sarcoidosis presenting with bilateral corneal scarring and dry eye.

Am J Ophthalmol Case Rep 2020 Sep 17;19:100790. Epub 2020 Jun 17.

The Wilmer Eye Institute, The Johns Hopkins University Medical School, Baltimore, MD, USA.

Purpose: To report the case of a patient who presents with multiple progressive ocular diseases who is diagnosed with concurrent primary Sjögren's syndrome and isolated ocular sarcoidosis.

Observation: A 60-year-old woman was referred for dry eye disease, bilateral interstitial keratitis, anterior uveitis, and progressive glaucoma. There was clinical suspicion of an autoimmune etiology due to her ocular history, risk factors, and presentation. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320313PMC
September 2020

Atypical Valsalva retinopathy from habitual ear popping.

Am J Ophthalmol Case Rep 2020 Sep 17;19:100785. Epub 2020 Jun 17.

Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USA.

Purpose: To report a unique case of Valsalva retinopathy associated with ear popping behavior.

Observations: A 57-year-old woman with a history of well-controlled hypertension presented with episodes of seeing "spots" in her left eye for many years. Her most recent episode failed to resolve spontaneously. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321967PMC
September 2020

Primary recurrent orbital schwannoma treated with surgical excision and Mitomycin-C.

Am J Ophthalmol Case Rep 2020 Sep 15;19:100784. Epub 2020 Jun 15.

Department of Ophthalmology, Tung Wah Eastern Hosptial, Causewaybay, Hong Kong.

Purpose: Primary orbital schwannoma (POS) is a slow growing, benign encapsulated peripheral nerve sheath tumor that occurs infrequently within the orbit. Recurrence of POS is extremely rare. Previous speculations for reasons of recurrence include incomplete excision and tumor seeding. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315101PMC
September 2020

Cyclodialysis cleft repair with goniotomy for the control of post-operative ocular hypertension.

Am J Ophthalmol Case Rep 2020 Sep 18;19:100781. Epub 2020 Jun 18.

University of Michigan, Kellogg Eye Center, Ann Arbor, MI, USA.

Purpose: In this case of iatrogenic cyclodialysis cleft, we describe a technique in which a nasal goniotomy is coupled with indirect cyclodialysis cleft (CDC) repair in order to minimize acute post-operative ocular hypertension, which is common following cyclodialysis cleft closure.

Observations: This novel technique was simple, convenient, and effective in controlling intraocular pressure (IOP) for the patient.

Conclusions And Importance: IOP frequently spikes to dangerously high levels following CDC closure. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321971PMC
September 2020

Severe retinitis pigmentosa phenotype associated with novel CNGB1 variants.

Am J Ophthalmol Case Rep 2020 Sep 13;19:100780. Epub 2020 Jun 13.

Menoufia University, Gamal Abdelnasser St, Shebin El-Kom, Egypt.

Purpose: To report a severe phenotype of retinitis pigmentosa associated with novel mutations in .

Observations: Six siblings, age range 50-75 years old, were examined using optical coherence tomography and fundus autofluorescene, electroretinogram testing, Goldman visual field testing, and genetic testing using next generation sequencing.In four affected siblings, two novel compound heterozygous variants in were detected: in exon 26 the missense variant c. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315105PMC
September 2020

Corneal melt following corneal tattooing with carbon-based ink.

Am J Ophthalmol Case Rep 2020 Sep 10;19:100779. Epub 2020 Jun 10.

Asian Eye Institute, Makati, Philippines.

Purpose: to report a case of corneal melting following corneal tattooing with carbon-based ink.

Observations: A 67 year old female with a phthisical eye underwent corneal tattooing with carbon-based ink for purpose of cosmesis. The procedure was uncomplicated. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315104PMC
September 2020

Lymphoma masquerading as occlusive retinal vasculitis: A case study.

Am J Ophthalmol Case Rep 2020 Sep 10;19:100777. Epub 2020 Jun 10.

The Retina Institute, St. Louis, MO, USA.

Purpose: To describe a case of retinal lymphoma presenting as an occlusive retinal vasculitis without vitritis that was exquisitely responsive to intravitreal dexamethasone implant (IVDI).

Observation: A 66-year old male presented with decreased vision in the right eye and was diagnosed with occlusive retinal vasculitis and prominent cystoid macular edema though he lacked vitritis. A complete systemic workup for infectious, inflammatory, and infiltrative etiologies was unremarkable. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320315PMC
September 2020

Choroidal detachment-induced secondary angle-closure after trabeculectomy in patient with ocular venous congestion: A case report.

Am J Ophthalmol Case Rep 2020 Sep 15;19:100782. Epub 2020 Jun 15.

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of 
Medicine, Kyoto, Japan.

Purpose: To report a particular circumstance that led to the abnormal complication of choroidal detachment (CD)-induced secondary angle-closure after trabeculectomy with mitomycin C (MMC).

Observations: An 82-year-old Japanese male patient with underlying chronic obstructive pulmonary disease and suspicion of ocular venous congestion in both eyes whom diagnosed as primary open-angle glaucoma with uncontrolled intraocular pressure (IOP) of his left eye then underwent an uneventful trabeculectomy with MMC. After the surgery, his left eye had high IOP with a shallow anterior chamber (A/C) but the bleb was hyperfiltration. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306613PMC
September 2020

Scleral fixation of fluocinolone acetonide implant.

Am J Ophthalmol Case Rep 2020 Sep 12;19:100775. Epub 2020 Jun 12.

Illinois Retina Associates, Chicago, IL, USA.

Purpose: To report on the technique of scleral fixation of fluocinolone acetonide (FAc) implant in 2 eyes with recalcitrant diabetic macular edema (DME).

Observations: Two eyes of 2 patients with persistent DME, partially responsive to anti-VEGF therapy, underwent intravitreal FAc implant injection. First case had a history of pars plana vitrectomy (PPV) and scleral fixated posterior chamber intraocular lens implant (PCIOL) for retained lens fragments and dislocated IOL. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305402PMC
September 2020

Case series: Delayed diagnoses of Acanthamoeba keratitis.

Am J Ophthalmol Case Rep 2020 Sep 10;19:100778. Epub 2020 Jun 10.

Wilmer Eye Institute, Johns Hopkins University School of Medicine, 600 N Wolfe St, Wilmer, Baltimore, MD, 21287, USA.

Purpose: To describe two cases of keratitis in contact lens wearers misdiagnosed as keratitis.

Observations: Case 1 is a 54-year-old male that was misdiagnosed with keratitis who developed advanced keratitis. His treatment course was complex and involved both medical therapy and surgical intervention with poor resolution. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298357PMC
September 2020

Swept source optical coherence tomography findings in a severe traumatic maculopathy following firework ocular injury.

Am J Ophthalmol Case Rep 2020 Sep 8;19:100776. Epub 2020 Jun 8.

Eye Clinic, Neuromuscolar and Sense Organs Department, Careggi University Hospital, Largo Brambilla, 3, 50134, Florence, Italy.

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http://dx.doi.org/10.1016/j.ajoc.2020.100776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298391PMC
September 2020

A case of the blues: Inadvertent ocular injury from accidental instillation of blue ink.

Am J Ophthalmol Case Rep 2020 Sep 10;19:100773. Epub 2020 Jun 10.

Department of Ophthalmology, Weill Cornell Medical College, 1305 York Avenue, New York, NY, 10021, USA.

Purpose: Many consumer products and non-ophthalmic medications are packaged in plastic "eye dropper" bottles, posing a risk of accidental ocular chemical injury when these substances are mistaken for eye drops.

Observations: We present the case of an elderly glaucoma patient who mistook blue stamper ink for the glaucoma medication Combigan®, and suffered ocular injury as a result.

Conclusions And Importance: The packaging of non-ophthalmic products in plastic "eye dropper" bottles poses a significant risk of accidental ocular chemical injury. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296186PMC
September 2020

Rapid visual field constriction in a patient with retinitis pigmentosa and pituitary adenoma.

Am J Ophthalmol Case Rep 2020 Sep 2;19:100762. Epub 2020 Jun 2.

Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan, 1000 Wall Street, Ann Arbor, MI, 48105, USA.

Purpose: To report a case of pituitary adenoma in a patient with retinitis pigmentosa (RP) and consequent rapid constriction of the visual field in each eye, which is atypical for either of these pathologies.

Observations: A 45-year old male, with a long-standing history of RP, presented with rapid vision loss over 3 months. Examination revealed a severe drop in visual acuity and significant progression of concentric visual field constriction in each eye compared to 3 months prior. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296332PMC
September 2020

Seronegative ocular toxoplasma panuveitis in an immunocompetent patient.

Am J Ophthalmol Case Rep 2020 Sep 15;19:100745. Epub 2020 May 15.

Department of Ophthalmology, The University of Kansas School of Medicine, Kansas City, KS, USA.

Purpose: Toxoplasma gondii is the most common cause of infectious posterior uveitis worldwide in immunocompetent patients. Despite its prevalence, diagnosis can still be challenging and vision-threatening in cases with atypical presentations. This case exemplifies the importance of clinical exam and additional workup when required despite negative initial serology results. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296335PMC
September 2020

Intra corneal ring segment implantation with lenticule assisted stromal augmentation for crosslinking in thin corneas.

Am J Ophthalmol Case Rep 2020 Sep 5;19:100726. Epub 2020 Jun 5.

Centre for Sight, B-5/24 Safdarjung Enclave, New Delhi, 110057, India.

Purpose: To evaluate the safety and efficacy of intra corneal ring segment (ICRS) implantation combined with crosslinking (CXL) using a Small Incision Lenticule Extraction (SMILE) lenticule for intraoperative stromal augmentation in thin corneas.

Observations: The procedure was performed in three eyes of progressive keratoconus or post refractive surgery corneal ectasia, with a preoperative mean thinnest pachymetry of 389.34 ± 5. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298359PMC
September 2020

Torpedo maculopathy complicated by choroidal neovascularization.

Am J Ophthalmol Case Rep 2020 Sep 6;19:100772. Epub 2020 Jun 6.

University of Pittsburgh School of Medicine, United States.

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http://dx.doi.org/10.1016/j.ajoc.2020.100772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287237PMC
September 2020

Rhino-orbital-cerebral mucormycosis (ROCM) and associated cerebritis treated with adjuvant retrobulbar amphotericin B.

Am J Ophthalmol Case Rep 2020 Sep 6;19:100771. Epub 2020 Jun 6.

California Pacific Medical Center, San Francisco, CA, United States.

Purpose: We report a case of rhino-orbital-cerebral mucormycosis (ROCM) with focal anterior cerebritis treated favorably with retrobulbar amphotericin B and systemic antifungals.

Observations: A 55-year-old diabetic male presented to the emergency department with left sided proptosis, left temple headache, maxillary sinus pain, and diplopia of 3 days duration. Biopsy results from the left middle turbinate, ethmoid, and maxillary sinus revealed broad and irregular non-septate hyphae consistent with mucormycosis. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287239PMC
September 2020

Contribution of swept-source OCT-angiography in analysis of choroidal osteoma and its quiescent neovascular complications: A case study.

Am J Ophthalmol Case Rep 2020 Sep 6;19:100769. Epub 2020 Jun 6.

Ophthalmology Department, Croix-Rousse Teaching Hospital, Lyon, France.

Purpose: Choroidal osteoma (CO) is a rare benign tumor of the choroid. Improvements in Optical Coherence Tomography (OCT) technologies, notably swept-source (SS), enables a better visualization of the choroid with deeper signal penetration in the tissues.

Observation: We describe SS-OCT and OCT-angiography findings in a 30-year-old patient with CO. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287234PMC
September 2020

Optical coherence tomography angiography findings in macular toxoplasma retinochoroiditis: A case report.

Am J Ophthalmol Case Rep 2020 Sep 2;19:100764. Epub 2020 Jun 2.

Department of Ophthalmology, University of Puerto Rico School of Medicine, Medical Sciences Campus, San Juan, PR, 00921, USA.

Purpose: To report the optical coherence tomography angiography (OCT-A) findings in a patient with macular toxoplasma retinochoroiditis (TRC).

Observations: A 14-year old female presented with a 2-week history of decreased vision of her right eye. Upon presentation, on the right eye, visual acuity was 20/200 and the fundus revealed 2+ vitritis and an active parafoveal area of retinitis superotemporally. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287232PMC
September 2020

Visual recovery and vascular reperfusion after vaso-occlusive retinopathy from anti-phospholipid syndrome associated with systemic lupus erythematosus.

Am J Ophthalmol Case Rep 2020 Sep 2;19:100763. Epub 2020 Jun 2.

Cleveland Clinic Cole Eye Institute, 9500 Euclid Avenue I-32, Cleveland, OH, 44195, USA.

Purpose: To report a case of visual recovery and vascular reperfusion after vaso-occlusive retinopathy from anti-phospholipid syndrome associated with systemic lupus erythematosus.

Observations: A 15-year-old boy with a known diagnosis of systemic lupus erythematosus and a clinically significant anti-phospholipid panel presented with sudden vision loss in the left eye. Examination and ocular imaging revealed signs of vaso-occlusive retinopathy. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287235PMC
September 2020

On the axial location of Gunn's dots.

Am J Ophthalmol Case Rep 2020 Sep 1;19:100757. Epub 2020 Jun 1.

Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, 419 W. Redwood Street, Baltimore, MD, 21201, USA.

Purpose: To determine the axial location of Gunn's dots in the retina.

Methods: Adaptive optics scanning laser ophthalmoscopy (AOSLO) images and adaptive optics - optical coherence tomography (AO-OCT) volumes were collected from a region where Gunn's dots were found inferior to the optic disc from a subject determined by clinical examination to be a glaucoma suspect. AO-OCT volumes were also collected along the horizontal and vertical meridians from six healthy subjects and one glaucoma subject to identify and document other occurrences of Gunn's dots. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287238PMC
September 2020

Decentration of a toric intraocular lens implant in a patient with simple megalocornea.

Authors:
Irene C Kuo

Am J Ophthalmol Case Rep 2020 Sep 30;19:100754. Epub 2020 May 30.

Wilmer Eye Institute, Department of Ophthalmology, Johns Hopkins University School of Medicine, 4924 Campbell Blvd. #100, Baltimore, MD, 21236, USA.

Purpose: To describe a patient who developed radial displacement of the capsular bag and toric intraocular lens implant within approximately 5 weeks after surgery.

Observations: A patient underwent uncomplicated cataract extraction and implantation of a toric IOL for 2.5 diopters (D) of preoperative corneal astigmatism. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287240PMC
September 2020

Minimally interface vitrectomy for rhegmatogenous retinal detachment with a single break in young patients.

Am J Ophthalmol Case Rep 2020 Sep 28;19:100739. Epub 2020 May 28.

Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.

Purpose: This study evaluates a new surgical technique consisting of minimal vitreous removal under air (minimal interface vitrectomy; MIV) to reduce postoperative complications while preserving the ability to address surgical factors at the retinal break.

Methods: This retrospective analysis examined the outcomes of minimal interface vitrectomies in consecutive cases, with a minimum 12-month follow-up period, of primary rhegmatogenous retinal detachment (RRD), recurrent RRD after pars plana vitrectomy (PPV), or failed surgery after primary scleral buckling surgery (SBS).

Results: Twelve eyes of 12 patients with RRD underwent MIV. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287242PMC
September 2020

Optical coherence tomography angiography findings of choroidal neovascularization secondary to laser injury: A case report.

Am J Ophthalmol Case Rep 2020 Sep 2;19:100767. Epub 2020 Jun 2.

Department of Ophthalmology, Intercity Hospital and Paris Est University, Créteil, France.

Purpose: To report a case of choroidal neovascularization (CNV) secondary to laser injury imaged by optical coherence tomography angiography (OCTA) and treated by intravitreal anti-vascular endothelial growth factor (VEGF).

Observations: A 14-year-old boy presented with vision loss and central scotoma in the right eye (RE) in the last month, after having stared at the beam of a laser pointer. At presentation, his best-corrected visual acuity (BCVA) in the RE was 20/40 and spectral-domain OCT (SD-OCT) showed an interruption of ellipsoid zone and the presence of an hyperrelfective lesion in subfoveal region. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286982PMC
September 2020

Multimodal imaging reveals pathological edges of disease activity in tuberculosis-associated multifocal serpiginoid chorioiditis.

Am J Ophthalmol Case Rep 2020 Sep 2;19:100766. Epub 2020 Jun 2.

USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.

Tuberculosis associated serpiginous-like choroidopathy can lead to significant vision loss. The anatomical cause for this visual decline can be elucidated using multimodal retinal imaging. Imaging modalities used in this case, most notably, optical coherence tomography angiography (OCTA), demonstrated specific atrophy of the choriocapillaris. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286979PMC
September 2020

Complicated case of conjunctivitis in Sjögren's syndrome.

Am J Ophthalmol Case Rep 2020 Sep 2;19:100765. Epub 2020 Jun 2.

Gavin Herbert Eye Institute, University of California, Irvine, 92697, United States.

Purpose: To report a case of conjunctivitis due to Mycobacterium abscessus in the setting of keratoconjunctivitis sicca due to Sjögren's syndrome in the absence of other known risk factors such as surgery, trauma or immunosuppressive therapy.

Observations: A 61-year-old woman with a history of keratoconjunctivitis sicca secondary to Sjögren's syndrome presented with dryness, irritation, redness, and discharge in her left eye for 2 months. She was diagnosed with chronic conjunctivitis and began a regimen of moxifloxacin and an ocular ointment of dexamethasone, neomycin, and polymyxin with no improvement of symptoms. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286968PMC
September 2020

Self-retained cryopreserved amniotic membrane in treating acute ocular graft-versus-host-disease (oGVHD).

Am J Ophthalmol Case Rep 2020 Sep 31;19:100761. Epub 2020 May 31.

Florida International University, Herbert Wertheim College of Medicine, Miami, 11200 SW, 8th St, 33199, FL, USA.

Purpose: To report successful management of acute ocular graft-versus-host disease (oGVHD) by self-retained cryopreserved amniotic membrane (AM).

Observations: A 69-year-old male developed acute oGVHD following hematopoietic stem cell transplantation (HSCT) with severe dryness, pain, photophobia, and blurred vision, the right eye worse than the left eye. Despite topical artificial tears, corticosteroids, and bandage contact lens (BCL) for two weeks, his right eye deteriorated with increasing redness and blurred vision and presented with diffuse conjunctival inflammation, severe superficial punctate keratitis, and corneal and limbal epithelial defect. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276382PMC
September 2020

Capsulorhexis challenge with long anterior lens zonules.

Am J Ophthalmol Case Rep 2020 Sep 27;19:100756. Epub 2020 May 27.

Illinois Eye Institute, Department of Clinical Education, Illinois College of Optometry, 3241, S. Michigan Ave, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.ajoc.2020.100756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276380PMC
September 2020

suture tube ccclusion of the Baerveldt glaucoma implant for management of postoperative hypotony: A case series.

Am J Ophthalmol Case Rep 2020 Sep 30;19:100752. Epub 2020 May 30.

Department of Ophthalmology and Visual Sciences, Dalhousie University, 1276 South Park, Street, Room 2035D, 2 West Victoria Building, Halifax, Nova Scotia, B3H 2Y9, Canada.

Purpose: Delayed hypotony can be a vision threatening complication following aqueous shunt surgery in patients with glaucoma. Multiple medical and surgical management strategies have been utilized, but results have been inconsistent. The present case series describes management of delayed hypotony associated with the Baerveldt glaucoma implant (BGI) by surgically introducing 4-0 polypropylene suture into the tube lumen. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276387PMC
September 2020

Staphyloma-related chorioretinal folds.

Am J Ophthalmol Case Rep 2020 Sep 26;19:100747. Epub 2020 May 26.

Center for Imaging and Laser, 11 Rue Antoine Bourdelle, 75015, Paris, France.

Purpose: To report a case of bilateral idiopathic chorioretinal folds that seemed to be related to an atypical staphyloma.

Observations: A 49-year old man without medical history consulted for slight vision loss and metamorphopsia in the left eye. The ophthalmologic examination revealed moderate myopia and bilateral chorioretinal folds in the posterior pole, confirmed by multimodal imaging. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281792PMC
September 2020

Monocular hemianopia secondary to stroke.

Am J Ophthalmol Case Rep 2020 Sep 28;19:100758. Epub 2020 May 28.

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.

Purpose: As a general rule, homonymous hemianopic defects localize to the retrochiasmal visual pathway and a monocular defect localizes at or anterior to the chiasm. We report three patients with a monocular hemianopia on automated static perimetry following cerebral stroke.

Observations: In this retrospective, consecutive case series, the charts of individuals presenting with stroke and monocular hemianopia were reviewed. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270541PMC
September 2020

Bilateral optic disc pits in a pediatric patient with Cobb syndrome.

Am J Ophthalmol Case Rep 2020 Sep 18;19:100749. Epub 2020 May 18.

Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USA.

Purpose: To describe a patient with Cobb Syndrome, a rare congenital disorder characterized by cutaneous and spinal arteriovenous malformations, who was found to have bilateral optic nerve pits.

Observations: A 15-year-old boy diagnosed with Cobb Syndrome, manifesting as a large cutaneous port-wine stain associated with an underlying left paraspinous arteriovenous malformation resulting in severe scoliosis, presented for a screening ophthalmological exam. The patient had no visual symptoms. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270543PMC
September 2020

Excisional goniotomy with Kahook Dual Blade in a patient with glaucoma secondary to Transthyretin Amyloidosis.

Am J Ophthalmol Case Rep 2020 Sep 20;19:100750. Epub 2020 May 20.

Grippo Glaucoma and Cataract Center, Buenos Aires, Argentina.

Purpose: To report for the first time the successful use of the Kahook Dual Blade excisional goniotomy technique in a patient with Transthyretin Amyloidosis.

Patient And Methods: The Kahook Dual Blade is a single use ab interno trabeculectomy device that removes the trabecular meshwork reducing aqueous humor outflow resistance. A patient with Transthyretin Amyloidosis underwent this procedure. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267710PMC
September 2020

Vitreomacular traction associated with papillitis.

Am J Ophthalmol Case Rep 2020 Sep 26;19:100759. Epub 2020 May 26.

Department of Ophthalmology, University of California, San Francisco, USA.

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http://dx.doi.org/10.1016/j.ajoc.2020.100759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262546PMC
September 2020

Treatment of periocular basal cell carcinoma with neoadjuvant vismodegib.

Am J Ophthalmol Case Rep 2020 Sep 23;19:100755. Epub 2020 May 23.

Baylor Scott and White Department of Ophthalmology - Texas A&M University, 1815 S 31st Street, Temple, TX, 76508, USA.

Purpose: To report a case of a locally advanced periocular basal cell carcinoma treated with neoadjuvant Vismodegib therapy prior to surgery.

Observations: A 63-year-old female presented to the oculoplastics clinic with biopsy-proven basal cell carcinoma of the right periorbital region causing significant cicatricial ectropion of the right lower eyelid. The medial canthal lesion involved nearly the entire right lower eyelid with extension onto the cheek, the medial half of the right upper eyelid, the palpebral and bulbar conjunctiva, as well as the right lacrimal system. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262551PMC
September 2020

A rare case of neurofibromatosis type I with unilateral congenital ectropion uveae and glaucoma.

Am J Ophthalmol Case Rep 2020 Sep 24;19:100753. Epub 2020 May 24.

Aravind Eye Hospital, Poonamallee High Road, Noombal, Chennai, 600077, Tamilnadu, India.

Purpose: Neurofibromatosis Type I (NF-1) is a neurocutaneous disease affecting the skin, eye and peripheral nervous system. Congenital glaucoma is a rare association, but can be a prelude to the diagnosis of NF-1 later in life. We report this unusual association in a child and discuss the possible underlying pathophysiologic mechanisms. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260431PMC
September 2020

Periorbital myxedema treated with intralesional hyaluronidase.

Am J Ophthalmol Case Rep 2020 Sep 25;19:100751. Epub 2020 May 25.

Bay Area Cosmetic Dermatology, 2299 Post Street, #312, San Francisco, CA, USA.

Purpose: Periorbital myxedema is one the most challenging symptoms for patients with Graves' eye disease (GED). The treatment of this condition is complex and often unsatisfactory. This case demonstrates the use of intralesional hyaluronidase to treat cosmetically concerning periorbital myxedema. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262547PMC
September 2020

Swept-source optical coherence tomography angiography findings of diabetic papillopathy after intravitreal bevacizumab.

Am J Ophthalmol Case Rep 2020 Sep 16;19:100748. Epub 2020 May 16.

Department of Ophthalmology, Jeju National University College of Medicine, Jeju-si, Jeju-do, Republic of Korea.

Purpose: We report a case of diabetic papillopathy (DP) treated with intravitreal bevacizumab injections and evaluated for disc vessel changes using swept-source optical coherence tomography angiography (SS-OCTA).

Observations: A 52-year-old man was referred with a 1-week history of acute painless decreased vision in both eyes (OU). His best-corrected visual acuity (BCVA) was 20/40 in the right eye (OD) and 20/100 in the left eye (OS). Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256312PMC
September 2020

Clinical and pathological characterization of persistent fetal vasculature associated with vitreous hemorrhage.

Am J Ophthalmol Case Rep 2020 Sep 18;19:100743. Epub 2020 May 18.

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Purpose: To provide clinical and pathological features of posterior persistent fetal vasculature (PFV) presenting with vitreous hemorrhage.

Observations: Case 1 was a one-year old male with PFV reaching up to the posterior lens capsule. Case 2 and 3 both had history of blunt trauma. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256462PMC
September 2020

Papillomacular retinoschisis associated with glaucoma: Response to topical carbonic anhydrase inhibitor.

Am J Ophthalmol Case Rep 2020 Sep 19;19:100741. Epub 2020 May 19.

Department of Ophthalmology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, Japan.

Purpose: We report the clinical courses of two patients with papillomacular retinoschisis in eyes with advanced glaucomatous optic neuropathy.

Observations: In case 1, a 67-year-old woman was diagnosed with papillomacular retinoschisis and normal tension glaucoma in the left eye. Her medication was switched from topical latanoprost to brinzolamide, resulting in gradual improvement in the papillomacular retinoschisis thereafter. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260430PMC
September 2020

Circumpapillary collateral vessel development in iatrogenic central retinal artery occlusion observed using OCT angiography.

Am J Ophthalmol Case Rep 2020 Sep 11;19:100740. Epub 2020 May 11.

Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan.

Purpose: It has been reported that peripapillary loops develop after central retinal artery occlusion (CRAO). Although cilioretinal anastomoses have been shown by fluorescein angiography (FA) and indocyanine green angiography, these examinations cannot confirm the structural continuity between the retinal arteries and the posterior ciliary arteries. In the current report, we followed a patient with iatrogenic CRAO in which circumpapillary collaterals formed and assessed the connection between these two vascular systems using optical coherence tomography angiography (OCTA). Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256303PMC
September 2020

Bilateral macular detachment: Choroid as a sanctuary of acute lymphoblastic leukemia.

Am J Ophthalmol Case Rep 2020 Sep 13;19:100746. Epub 2020 May 13.

Buenos Aires Macula, Buenos Aires, Argentina.

Purpose: To describe a bilateral macular detachment as the only sign of acute lymphoblastic leukemia relapse and prompt reversal with total body irradiation without ocular protection.

Observations: We present the case of a 20-year-old patient, diagnosed with a high-risk phy-negative, pre-B acute lymphoblastic leukemia (ALL), with a positive MLL gene rearrangement. After a Berlin-Frankfurt-Munster-like regimen chemotherapy protocol and a first complete remission, ALL relapse was diagnosed, so he was commenced on a FlaG-Ida protocol (fludarabine, idarubicin, granulocyte-colony stimulating factor, and high-dose cytarabine). Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251383PMC
September 2020

Femtosecond laser-assisted cataract surgery in management of posterior capsule tear following blunt trauma: Case report and review of literature.

Am J Ophthalmol Case Rep 2020 Sep 16;19:100742. Epub 2020 May 16.

Department of Ophthalmology, Northwestern Feinberg School of Medicine, Chicago, IL, USA.

Purpose: To describe the diagnosis and management of a patient with rupture of the posterior capsule (PC) following blunt trauma to the left eye.

Observation: 68 year-old man presented with complaints of left eye pain, blurry vision and photophobia after getting hit in the left eye with a baseball. He was found to have a posterior capsule rupture, as well as mydriasis and zonular dialysis without formation of intumescent traumatic cataract. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251535PMC
September 2020

Modified insertion technique for a sustained-release dexamethasone intravitreal implant (Ozurdex®).

Am J Ophthalmol Case Rep 2020 Sep 30;19:100725. Epub 2020 Apr 30.

Southern California Desert Retina Consultants, 36949, Cook St. Suite #101, Palm Desert, CA, USA.

Purpose: We describe a modified injection technique that adheres a sustained-release dexamethasone intravitreal implant (Ozurdex®) to the vitreous base.

Observations: This modified technique was applied after removal of a prior dislocated Ozurdex® that migrated into the anterior chamber in one patient, and also on another patient bothered by perception of a large floater induced by a free-floating Ozurdex® in the vitreous cavity previously inserted with the conventional technique. The main feature of this new technique consisted of altering the conventional "bevel-up" orientation of the insertion needle tip towards the vitreous cavity to the modified "bevel-down" orientation of the needle tip directed towards the pars plana and vitreous base, for the purpose of adhering a portion of or the entire dexamethasone implant to the vitreous base. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248650PMC
September 2020

Vitrectomy using the Eckardt temporary keratoprosthesis.

Am J Ophthalmol Case Rep 2020 Sep 1;19:100709. Epub 2020 May 1.

Bascom Palmer Eye Institute, Miami, FL, USA.

Purpose: to present the now vitrectomy technique through a limbus via preexisting holes in the Eckardt TKP.

Methods: the surgical technique performed in a case of four-year-old girl presented with a complete hyphema and vitreous hemorrhage in the left eye.

Results: the vitrectomy was performed vial a limbal approach from the TKP without making additional sclerotomies. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251374PMC
September 2020

Optic neuropathy due to chronic lymphocytic leukemia: The first manifestation of the disease.

Am J Ophthalmol Case Rep 2020 Jun 28;18:100603. Epub 2020 Jan 28.

Ophthalmology Department, Centro Hospitalar Universitário de Lisboa Central, Alameda Santo António dos Capuchos, 1169-050, Lisboa, Portugal.

Purpose: Chronic lymphocytic leukemia (CLL) is the most common lymphoproliferative disorder in the western world. The involvement of the central nervous system (CNS) or the optic nerve in CLL, however, is rare. We report a case of a previously untreated patient with CLL whose first manifestation of the disease was a progressive visual loss caused by optic neuropathy. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244917PMC

Early experience with teprotumumab for chronic thyroid eye disease.

Am J Ophthalmol Case Rep 2020 Sep 15;19:100744. Epub 2020 May 15.

Division of Oculofacial Plastic and Reconstructive Surgery, UC San Diego Viterbi Family Department of Ophthalmology, La Jolla, CA, USA.

Purpose: To report the first case of a patient with chronic thyroid eye disease (TED) treated with teprotumumab.

Observations: A 50-year-old female with a 3-year history of Graves' disease presented with bilateral exophthalmos greatest on the left side. She was followed for 2 years with stable proptosis measurements (23mm OD, 28mm OS). Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243051PMC
September 2020

and endogenous panophthalmitis: clinical and histopathological features.

Am J Ophthalmol Case Rep 2020 Sep 11;19:100738. Epub 2020 May 11.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, USA.

Purpose: To report an unusual case of endogenous panophthalmitis involving and describe its clinical and histopathological features.

Findings: A 30 year-old man with history of human immunodeficiency virus, polysubstance abuse, syphilis, and recently treated pneumonia presented with polymicrobial endogenous panophthalmitis. Two separate ocular specimens confirmed simultaneous and involvement. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240712PMC
September 2020

Gonioscopy-assisted transluminal trabeculotomy using an illuminated catheter for infantile primary congenital glaucoma. Case series.

Am J Ophthalmol Case Rep 2020 Sep 8;19:100733. Epub 2020 May 8.

Swiss Eye Centre, Avenue de Rumine 64, 1005, Lausanne, Switzerland.

Purpose: To describe our experience of Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) in four eyes with infantile primary congenital glaucoma (PCG).

Observations: We report the first two GATT procedures performed in six-month-old infants with PCG. We also report the same procedure in two eyes of a two-year-old boy with PCG who had previous goniotomies with subsequent peripheral anterior synechiae formation. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240732PMC
September 2020