Search our Database of Scientific Publications and Authors

I’m looking for a

    25228 results match your criteria American journal of ophthalmology[Journal]

    1 OF 505

    Longitudinal Change in Central Corneal Thickness in the Tema Eye Survey.
    Am J Ophthalmol 2017 Nov 12. Epub 2017 Nov 12.
    Moorefields Eye Hospital and Department of Epidemiology and Genetics, Institute of Ophthalmology, University College of London, London, UK.
    Purpose: To determine the change and rate of change in central corneal thickness (CCT) and their determinants.

    Design: Longitudinal observational population-based study.

    Methods: 758 normal and 58 glaucomatous subjects underwent complete eye examination, with CCT measurements at two separate visits. Read More

    Moving from Clinic to Home: What the Future Holds for Ophthalmic Telemedicine.
    Am J Ophthalmol 2017 Nov 11. Epub 2017 Nov 11.
    Pepose Vision Institute, Chesterfield, Missouri; Washington University School of Medicine, Saint Louis, Missouri. Electronic address:
    Purpose: To describe the expanding role of telemedicine in healthcare, the key criteria required for a successful device and program implementation, and the current and future role of home monitoring in ophthalmology.

    Design: Expert perspective METHODS: Analysis with real-world interpretation of home monitoring technologies including current adoption barriers and expanded future demands based on demographic and market forces.

    Results: Remote patient monitoring represents a paradigm shift in the way physicians care for patients. Read More

    Quantifying the Rate of Ellipsoid Zone Loss in Stargardt Disease.
    Am J Ophthalmol 2017 Nov 7. Epub 2017 Nov 7.
    Wilmer Eye Institute, Johns Hopkins Hospital, 600 N. Wolfe Street, Baltimore, MD 21287. Electronic address:
    Purpose: To determine a reliable method of using the ellipsoid zone (EZ) on optical coherence tomography (OCT) to track disease progression in Stardgardt disease (STGD).

    Design: retrospective reliability study METHODS: STGD patients with genetically confirmed ABCA4 gene mutations seen at the Wilmer Eye Institute with follow-up visits separated by at least 12 months were identified. Spectral domain optical coherence tomography (SD-OCT) macula volume scans centered at the fovea and fundus autofluorescence (FAF) images were obtained. Read More

    Inter-observer agreement among uveitis experts on uveitic diagnoses: the Standardization of Uveitis Nomenclature (SUN) experience.
    Am J Ophthalmol 2017 Nov 6. Epub 2017 Nov 6.
    Department of Medicine, Texas A& M University College of Medicine, College Station, TX, USA.
    Purpose: To evaluate the interobserver agreement among uveitis experts on the diagnosis of the specific uveitic disease.

    Design: Inter-observer agreement analysis METHODS: Five committees, each of 9 individuals, working in parallel, reviewed cases from a preliminary database of 25 uveitic diseases, collected by disease, and voted independently online whether the case was the disease in question or not. The agreement statistic, κ, was calculated for the 36 pairwise comparisons for each disease, and a mean κ was calculated for each disease. Read More

    AJO Centennial: Evolving concepts in the management of retinopathy of prematurity.
    Am J Ophthalmol 2017 Nov 3. Epub 2017 Nov 3.
    Vanderbilt Eye Institute, 2311 Pierce Avenue, Nashville, TN 37232.
    Purpose: The introduction of anti-vascular endothelial growth factor (VEGF) agents has stimulated considerable reexamination of treatment strategies for the management of retinopathy of prematurity (ROP). Herein we will summarize and review evolving concepts and provide a personal perspective on clinical management today and future directions of treatment.

    Design: Literature Review METHODS: To synthesize the evolving management concepts for diagnosis and treatment of retinopathy of prematurity and to provide interpretation and perspective on current emerging therapies. Read More

    Geographic and Demographic Variation in Use of Ranibizumab Versus Bevacizumab for Neovascular Age-related Macular Degeneration in the United States.
    Am J Ophthalmol 2017 Oct 27. Epub 2017 Oct 27.
    Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.
    Purpose: To examine demographic and geographic variation in the use of ranibizumab and bevacizumab for the treatment of neovascular age-related macular degeneration (AMD) among Medicare beneficiaries.

    Design: Retrospective cohort study.

    Methods: Using a 100% sample of Medicare claims data, we evaluated Medicare beneficiaries (N = 195 812) with an index claim for neovascular AMD between July 1, 2006, and June 30, 2009, to determine whether beneficiaries first received ranibizumab or bevacizumab following initial diagnosis. Read More

    Tractional Abnormalities of the Central Foveal Bouquet in Epiretinal Membranes: Clinical Spectrum and Pathophysiological Perspectives.
    Am J Ophthalmol 2017 Oct 26. Epub 2017 Oct 26.
    Retinal Disorders and Ophthalmic Genetics Division, Stein Eye Institute, University of California Los Angeles, Los Angeles, California; Greater Los Angeles VA Healthcare Center, Los Angeles, California. Electronic address:
    Purpose: To investigate the tractional alterations of the central bouquet (CB) in idiopathic epiretinal membranes (ERMs).

    Design: Retrospective, consecutive, observational case series.

    Methods: ERMs were classified according to a 4-stage grading system. Read More

    Leadership of United States Academic Departments of Ophthalmology: Chairperson Characteristics, Accomplishments, and Personal Insights.
    Am J Ophthalmol 2017 Nov 2. Epub 2017 Nov 2.
    Eye Care Services, Henry Ford Hospital, Detroit, MI.
    Purpose: To report on the characteristics, accomplishments, and past experiences of current academic ophthalmology department chairs.

    Design: Cross-sectional study.

    Setting: A confidential online survey. Read More

    Clinical and Radiological Evaluation of Periocular Infantile Hemangioma Treated With Oral Propranolol: A Case Series.
    Am J Ophthalmol 2017 Nov 15. Epub 2017 Nov 15.
    Department of Ophthalmology, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.
    Purpose: To evaluate the efficacy of propranolol (3 mg/kg/day) in the treatment of periocular infantile hemangioma (IH) based on clinical and radiological findings.

    Design: Prospective interventional case series.

    Methods: Study of previously untreated infants with IH conducted at the ophthalmology outpatient service of HC-FMUSP (Brazil). Read More

    Corneal Stroma Enhancement with Decellularized Stromal Laminas with or without Stem Cell Recellularization for Advanced Keratoconus.
    Am J Ophthalmol 2017 Nov 2. Epub 2017 Nov 2.
    Cornea, Cataract and Refractive Surgery Unit, Vissum Corporación, Alicante, Spain; Division of Ophthalmology, Universidad Miguel Hernández, Alicante, Spain. Electronic address:
    Purpose: Phase-1 study to preliminarily evaluate the safety and efficacy of decellularized human corneal stromal lamina transplantation with or without autologous adipose derived adult stem cells (ADASC) recellularization within the corneal stroma of patients with advanced keratoconus.

    Design: Phase one clinical trial METHODS: Femtosecond-assisted 120μm-thickness and 9mm-diameter laminas were obtained from the anterior stroma of human donor corneas and decellularized with a sodium dodecyl sulfate solution. Autologous ADASC were obtained by elective liposuction and cultured onto both sides of the lamina. Read More

    High-resolution Imaging in Male Germ Cell-Associated Kinase (MAK)-related Retinal Degeneration.
    Am J Ophthalmol 2017 Nov 16. Epub 2017 Nov 16.
    Department of Ophthalmology, University of California, San Francisco, San Francisco, California. Electronic address:
    Purpose: To describe the characteristics of MAK-related retinal degeneration using optical coherence tomography angiography (OCTA) and adaptive optics scanning laser ophthalmoscopy (AOSLO).

    Design: Cross-sectional study.

    Methods: Six patients with rod-cone degeneration and disease-causing mutations in MAK were evaluated with visual acuity, spectral-domain OCT, confocal AOSLO, and OCTA. Read More

    A Longitudinal Analysis of Peripapillary Choroidal Thinning in Healthy and Glaucoma Subjects.
    Am J Ophthalmol 2017 Nov 2. Epub 2017 Nov 2.
    Hamilton Glaucoma Center, Shiley Eye institute and Department of Ophthalmology, University of California, San Diego, CA.
    Purpose: To evaluate the rate of peripapillary choroidal thinning in glaucoma patients and healthy controls using spectral domain optical coherence tomography (SD-OCT).

    Design: Cohort study METHODS: Participants from the multicenter African Descent and Glaucoma Evaluation Study (ADAGES) and Diagnostic Innovations in Glaucoma Study (DIGS) were included. The San Diego Automated Segmentation Algorithm (SALSA) was used to automatically segment and measure peripapillary choroidal thickness (PCT) from circle scans centered on the optic nerve head. Read More

    Scleral Lenses Reduce the Need for Corneal Transplants in Severe Keratoconus.
    Am J Ophthalmol 2017 Nov 15. Epub 2017 Nov 15.
    Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium; Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
    Purpose: To investigate the success and failure rates of scleral lens correction in severe keratoconus.

    Design: Retrospective case series.

    Methods: Study population comprised patients with keratoconus who attended the keratoconus clinic at the Antwerp University Hospital, Belgium, between January 1, 2010, and December 31, 2014. Read More

    Prevalence of Vision Impairment in Older Adults in Rural China in 2014 and Comparisons With the 2006 China Nine-Province Survey.
    Am J Ophthalmol 2017 Nov 2. Epub 2017 Nov 2.
    Rehabilitation Administration Department, National Institute of Hospital Administration, Beijing, China.
    Purpose: To estimate the prevalence of vision impairment and blindness in 2014 among older adults in rural China with comparisons with the 2006 Nine-Province Survey.

    Design: Population-based, cross-sectional study.

    Methods: Geographical cluster sampling was used in randomly selecting residents from a rural county or semi-rural district within 9 provinces: Beijing, Jiangsu, Guangdong, Heilongjiang, Jiangxi, Hebei, Ningxia, Chongqing, and Yunnan. Read More

    Incidence and Etiology of Presumed Fourth Cranial Nerve Palsy: A Population-based Study.
    Am J Ophthalmol 2017 Nov 2. Epub 2017 Nov 2.
    Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota. Electronic address:
    Purpose: To determine the incidence of isolated, presumed fourth nerve palsy in a defined population, and to report the frequency of each cause.

    Design: Retrospective, population-based case series.

    Methods: A population-based database was used to identify all cases of isolated fourth nerve palsy in Olmsted County, Minnesota, USA diagnosed over a 15-year period (January 1, 1978 to December 31, 1992). Read More

    Development and Clinical Accuracy of a New Intraocular Lens Power Formula (VRF) Compared to Other Formulas.
    Am J Ophthalmol 2017 Nov 2. Epub 2017 Nov 2.
    Kiev Clinical Ophthalmology Hospital Eye Microsurgery Center, Kiev, Ukraine. Electronic address:
    Purpose: To develop and compare the accuracy and reproducibility of the VRF intraocular lens (IOL) power calculation formula with well-known methods.

    Design: Development and validation study.

    Methods: This analysis comprised 823 eyes of 823 patients at Kiev Clinical Ophthalmology Hospital Eye Microsurgery Center, Kiev, Ukraine, operated on by 1 surgeon with 3 different types of hydrophobic lenses: IQ SN60WF (494 eyes) and ReSTOR SN6AD1 (169 eyes) (Alcon Labs, Fort Worth, Texas, USA) and AMO Tecnis MF ZMB00 (160 eyes) (J&J Vision, Santa Ana, California, USA). Read More

    Uveitis and Juvenile Psoriatic Arthritis or Psoriasis.
    Am J Ophthalmol 2017 Oct 31. Epub 2017 Oct 31.
    Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon; Department of Medicine, Oregon Health & Science University, Portland, Oregon; Legacy Devers Eye Institute, Portland, Oregon. Electronic address:
    Purpose: To describe the phenotype of the uveitis that accompanies juvenile psoriatic arthritis or psoriasis.

    Design: Observational case series.

    Methods: Setting: Two university-based referral clinics: 1 in England, 1 in the United States. Read More

    Use of a Neural Net to Model the Impact of Optical Coherence Tomography Abnormalities on Vision in Age-related Macular Degeneration.
    Am J Ophthalmol 2017 Oct 31. Epub 2017 Oct 31.
    School of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom; Manchester Royal Eye Hospital, NHS Central Manchester University Hospitals, Manchester, United Kingdom.
    Purpose: To develop a neural network for the estimation of visual acuity from optical coherence tomography (OCT) images of patients with neovascular age-related macular degeneration (AMD) and to demonstrate its use to model the impact of specific controlled OCT changes on vision.

    Design: Artificial intelligence (neural network) study.

    Methods: We assessed 1400 OCT scans of patients with neovascular AMD. Read More

    Epidemiology of Primary Ophthalmic Inpatient Admissions in the United States.
    Am J Ophthalmol 2017 Oct 31. Epub 2017 Oct 31.
    Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address:
    Purpose: To determine the national estimates, demographics, and costs of inpatient eye care in the United States (US).

    Design: Retrospective cross-sectional study.

    Methods: National Inpatient Sample (NIS), a representative sample of all US community hospitals, was used to analyze inpatient admissions with a primary ophthalmic diagnosis from 2001 to 2014. Read More

    Corneal Abnormalities in Congenital Aniridia: Congenital Central Corneal Opacity Versus Aniridia-associated Keratopathy.
    Am J Ophthalmol 2017 Oct 31. Epub 2017 Oct 31.
    Department of Ophthalmology and the Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea. Electronic address:
    Purpose: To clinically characterize and compare 2 types of corneal abnormalities in patients with congenital aniridia: (1) congenital central corneal opacity from birth (CCO) and (2) aniridia-associated keratopathy (AAK) that develops progressively with age.

    Design: Retrospective cohort study.

    Methods: Medical records of Korean patients who were diagnosed with congenital aniridia at Seoul National University Hospital between 1991 and 2016 were reviewed. Read More

    The Expanded Spectrum of Perifoveal Exudative Vascular Anomalous Complex.
    Am J Ophthalmol 2017 Oct 27. Epub 2017 Oct 27.
    Department of Ophthalmology, University Vita-Salute, IRCCS Ospedale San Raffaele, Milan, Italy. Electronic address:
    Purpose: To expand our understanding of the uncommon entity, referred to as perifoveal exudative vascular anomalous complex (PEVAC) by describing multimodal imaging findings, including optical coherence tomography angiography (OCT-A).

    Design: Retrospective cohort study.

    Methods: Patients diagnosed with PEVAC were identified at 4 retina referral centers worldwide and underwent complete ophthalmologic examination including structural OCT, OCT-A, fluorescein angiography (FA), and indocyanine green angiography (ICGA). Read More

    SCORE2 Report 5: Vision-Related Function in Patients With Macular Edema Secondary to Central Retinal or Hemiretinal Vein Occlusion.
    Am J Ophthalmol 2017 Oct 23. Epub 2017 Oct 23.
    The Emmes Corporation, Rockville, Maryland. Electronic address:
    Purpose: To describe baseline vision-related function, measured with the National Eye Institute Visual Function Questionnaire (NEI VFQ-25), in patients with macular edema secondary to central retinal vein occlusion (CRVO) or hemiretinal vein occlusion (HRVO) in the Study of COmparative Treatments for REtinal Vein Occlusion 2 (SCORE2); evaluate the baseline relationship between NEI VFQ-25 scores with visual acuity letter score (VALS) and central retinal thickness; and compare baseline NEI VFQ-25 scores in SCORE2 participants with those in normal-vision reference populations and patients in other retinal vein occlusion trials.

    Design: Multicenter, noninferiority randomized controlled trial.

    Methods: SCORE2 was designed to assess whether intravitreal bevacizumab is noninferior to intravitreal aflibercept for treatment of decreased vision attributable to macular edema owing to CRVO or HRVO. Read More

    Macular Fluid Reduces Reproducibility of Choroidal Thickness Measurements on Enhanced Depth Optical Coherence Tomography.
    Am J Ophthalmol 2017 Oct 14. Epub 2017 Oct 14.
    Department of Ophthalmology, University of California, Davis, Sacramento, California. Electronic address:
    Purpose: To determine if different types of retinal fluid in the central macula affect the reproducibility of choroidal thickness (CT) measurements on enhanced depth imaging optical coherence tomography (EDI-OCT).

    Design: Retrospective reliability analysis.

    Methods: EDI-OCT images were obtained and the choroidal-scleral junction was analyzed through semiautomated segmentation. Read More

    Peripheral visual fields in ABCA4 Stargardt disease and correlation with disease extent on ultra-widefield fundus autofluorescence.
    Am J Ophthalmol 2017 Oct 14. Epub 2017 Oct 14.
    Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, United States. Electronic address:
    Purpose: To evaluate the disease extent on ultra-widefield fundus autofluorescence (UWF-FAF) in patients with ABCA4- Stargardt disease (STGD) and correlate this data with functional outcome measures.

    Design: Retrospective cross sectional study SETTING: Kellogg Eye Center, University of Michigan STUDY POPULATION: Sixty-five patients with clinical diagnosis and proven pathogenic variants in the ABCA4 gene.

    Observational Procedures: The UWF-FAF images were obtained using Optos 200- degrees and classified into three types. Read More

    Use of Donors Predisposed by Corneal Collagen Cross-linking in Penetrating Keratoplasty for Treating Patients With Keratoconus.
    Am J Ophthalmol 2017 Oct 13. Epub 2017 Oct 13.
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
    Purpose: To investigate whether use of donors predisposed by corneal collagen cross-linking (CXL) reduced myopic refractive errors for keratoconic eyes after penetrating keratoplasty (PK).

    Design: Randomized controlled trial.

    Methods: One hundred sixteen eyes of 116 patients with keratoconus from Zhongshan Ophthalmic Center were enrolled. Read More

    Early Response to Intravitreal Dexamethasone Implant Therapy in Diabetic Macular Edema May Predict Visual Outcome.
    Am J Ophthalmol 2017 Oct 13. Epub 2017 Oct 13.
    L.V. Prasad Eye Institute, Hyderabad, India. Electronic address:
    Purpose: To determine whether early visual acuity response to intravitreal dexamethasone implant therapy in diabetic macular edema (DME) is associated with long-term outcome.

    Design: Retrospective case series.

    Methods: Multicenter (8 sites) retrospective review of medical records of eyes with DME treated with 0. Read More

    Pregnancy-induced Changes in Corneal Biomechanics and Topography Are Thyroid Hormone Related.
    Am J Ophthalmol 2017 Oct 13. Epub 2017 Oct 13.
    Center for Applied Biotechnology and Molecular Medicine (CABMM), University of Zurich, Zurich, Switzerland; ELZA Institute, Dietikon, Switzerland; Faculty of Medicine, University of Geneva, Geneva, Switzerland; Department of Ophthalmology, USC Roski Eye Institute, USC Los Angeles, Los Angeles, California. Electronic address:
    Purpose: To identify biomechanical and topographic changes of the cornea during pregnancy and the postpartum period and its association to hormonal changes.

    Design: Prospective single-center observational cohort study.

    Methods: Participants were 24 pregnant women (48 eyes), monitored throughout pregnancy and after delivery. Read More

    Long-term Outcomes of Ocular Surface Stem Cell Allograft Transplantation.
    Am J Ophthalmol 2017 Oct 13. Epub 2017 Oct 13.
    Cincinnati Eye Institute, Edgewood, Kentucky; Department of Ophthalmology, University of Cincinnati, Cincinnati, Ohio. Electronic address:
    Purpose: To investigate the long-term outcomes of ocular surface stem cell allograft transplantation (OSST) in patients with total limbal stem cell deficiency (LSCD) owing to various etiologies with a follow-up ≥ 5 years.

    Design: Retrospective interventional cohort.

    Methods: Setting: Single tertiary referral hospital. Read More

    Diabetic Choroidopathy: Choroidal Vascular Density and Volume in Diabetic Retinopathy with Swept-Source Optical Coherence Tomography.
    Am J Ophthalmol 2017 Oct 5. Epub 2017 Oct 5.
    Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, 243 Charles Street, Boston, MA 02114. Electronic address:
    Purpose: To compare choroidal vascular density (CVD) and volume (CVV) in diabetic eyes and controls, using en face swept-source optical coherence tomography (SS-OCT).

    Design: Prospective cross-sectional study.

    Methods: ▪▪▪ SETTING: Multicenter PATIENT POPULATION: 143 diabetic eyes - 27 with no diabetic retinopathy (DR), 47 with nonproliferative DR (NPDR), 51 with NPDR and diabetic macular edema (DME), and 18 with proliferative DR (PDR), and 64 age-matched non-diabetic control eyes. Read More

    Elevated aqueous cytokine levels in eyes with ocular surface diseases.
    Am J Ophthalmol 2017 Oct 5. Epub 2017 Oct 5.
    Department of Ophthalmology, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
    Purpose: To evaluate cytokine and protein levels in the aqueous humor (AqH) of eyes with ocular surface diseases.

    Design: Prospective consecutive case series.

    Methods: This study includes 14 patients (62. Read More

    Outcomes and Prognostic Factors of Cataract Surgery in Adult Extreme Microphthalmos with Axial Length <18 mm or Corneal Diameter <8 mm.
    Am J Ophthalmol 2017 Oct 5. Epub 2017 Oct 5.
    Department of Ophthalmology and Eye Institute, EYE and ENT Hospital of Fudan University and Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China. Electronic address:
    Purpose: To study the long-term visual outcomes, complications and prognostic factors for cataract surgery in extreme microphthalmos.

    Design: Prospective cohort study.

    Methods: Thirty eyes with simple microphthalmos [11 eyes, axial length (AL) <18 mm], complex microphthalmos [8 eyes, AL <18 mm] and relative anterior microphthalmos [RAM, 11 eyes, corneal diameter (CD) <8 mm] who underwent cataract surgery (phacoemulsification) in our hospital were followed for a mean of 25. Read More

    Comparison of Glaucoma Progression Detection by Optical Coherence Tomography and Visual Field.
    Am J Ophthalmol 2017 Sep 27. Epub 2017 Sep 27.
    Casey Eye Institute, Oregon Health & Science University. Electronic address:
    Purpose: To compare longitudinal glaucoma progression detection using optical coherence tomography (OCT) and visual field (VF).

    Design: Validity assessment METHOD: We analyzed subjects with more than 5 follow-up visits (every 6 months) in the multi-center Advanced Imaging for Glaucoma Study. Fourier-domain optical coherence tomography (OCT) was used to map the thickness of the peripapillary retinal nerve fiber layer (NFL) and ganglion cell complex (GCC). Read More

    Optical Coherence Tomography Protocols for Screening of Hydroxychloroquine Retinopathy in Asian Patients.
    Am J Ophthalmol 2017 Sep 27. Epub 2017 Sep 27.
    Department of Ophthalmology, Hanyang University Hospital, Hanyang University College of Medicine, Seoul, Republic of Korea. Electronic address:
    Purpose: To investigate the distribution of outer retinal changes in hydroxychloroquine (HCQ) retinopathy and explore optical coherence tomography (OCT) protocols to maximize the sensitivity of HCQ retinopathy detection in Asian patients.

    Design: Diagnostic validity assessment METHODS: Setting: Institutional Patient Population: Forty-eight eyes (24 patients) with HCQ retinopathy underwent 6-mm horizontal and vertical line scans and 6 × 6-mm(2) volume scans using spectral-domain OCT (SD-OCT), and 9-mm line scans and 6 × 6-mm(2) and 12 × 9-mm(2) volume scans using swept-source OCT (SS-OCT).

    Observation Procedures: Distances from the fovea to the defective photoreceptors were measured in the temporal, nasal, superior, and inferior directions from line scan OCT images. Read More

    Differences in OCT Assessment of Bruch Membrane Opening Compared to Stereoscopic Photography for Estimating Cup-to-Disc Ratio.
    Am J Ophthalmol 2017 Sep 27. Epub 2017 Sep 27.
    Bascom Palmer Eye Institute, University of Miami, Miami, Florida, USA. Electronic address:
    Purpose: To compare the vertical and horizontal cup-to-disc ratio (VCDR, HCDR) by an updated optical coherence tomography (OCT) Bruch's membrane opening (BMO) algorithm and stereoscopic optic disc photograph readings by glaucoma specialists.

    Design: Reliability analysis.

    Methods: 195 eyes (116 glaucoma and 79 glaucoma suspects) of 99 patients with stereoscopic photos and OCT scans of the optic discs taken during the same visit were compared. Read More

    West Indies Glaucoma Laser Study (WIGLS): 1. 12-Month Efficacy of Selective Laser Trabeculoplasty in Afro-Caribbeans with Glaucoma.
    Am J Ophthalmol 2017 Sep 26. Epub 2017 Sep 26.
    Epidemiology Data Center, Graduate School of Public Health, University of Pittsburgh, PA.
    Purpose: To characterize the 12-month intraocular pressure (IOP)-lowering efficacy of selective laser trabeculoplasty (SLT) as sole therapy for primary open-angle glaucoma (POAG) in an Afro-Caribbean population.

    Design: Stepped-wedge trial.

    Methods: Subjects in St. Read More

    The ISNT Rule: How Often Does It Apply to Disc Photos and Retinal Nerve Fiber Layer Measurements in the Normal Population.
    Am J Ophthalmol 2017 Sep 22. Epub 2017 Sep 22.
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts. Electronic address:
    Purpose: To determine what percentage of normal eyes follow the ISNT rule, and whether ISNT rule variants may be more generalizable to the normal population.

    Design: Cross-sectional study.

    Methods: Setting: Institutional setting. Read More

    Corneal Higher-order Aberrations and Visual Improvement Following Corneal Transplantation in Treating Herpes Simplex Keratitis.
    Am J Ophthalmol 2017 Sep 21. Epub 2017 Sep 21.
    Department of Ophthalmology, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
    Purpose: To examine corneal higher-order aberrations (HOAs) and visual improvement following corneal transplantation in treating corneal scar caused by herpes simplex keratitis (HSK).

    Design: Retrospective consecutive case series.

    Methods: This study included a total of 52 eyes: 18 normal subjects, and 34 eyes of consecutive patients with corneal scar due to HSK who underwent penetrating keratoplasty (PKP, 17 eyes) or deep anterior lamellar keratoplasty (DALK, 17 eyes). Read More

    1 OF 505