25,677 results match your criteria American journal of ophthalmology[Journal]


Vitrectomy for diabetic macular edema: optical coherence tomography criteria and pathology of the vitreomacular interface.

Am J Ophthalmol 2018 Dec 14. Epub 2018 Dec 14.

Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany.

Purpose: To correlate spectral-domain optical coherence tomography (SD-OCT) criteria and clinical data with pathology of the vitreomacular interface (VMI) in eyes with diabetic macular edema (DME).

Design: Retrospective cross-sectional study and laboratory investigation.

Methods: We included specimens of 27 eyes of 26 patients with center-involved DME that underwent vitrectomy with peeling of the internal limiting membrane (ILM). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.12.004DOI Listing
December 2018

Five-year trends in multifocal electroretinogram for patients with birdshot chorioretinopathy.

Am J Ophthalmol 2018 Dec 14. Epub 2018 Dec 14.

Grenoble Alpes University, Grenoble, France; Department of Ophthalmology, Grenoble Alpes University Hospital, Grenoble, France.

Purpose: The aim of this study is to investigate temporal trends in multifocal ERG (mfERG) parameters and analyse their relationships with anatomical and functional markers in patients with Birdshot chorioretinopathy (BSCR).

Design: Prospective observational case series METHODS: 16 BSCR patients were include and underwent two standardized follow-up (FU) visits within five years following a baseline examination, including mfERG, visual acuity (VA), visual field (VF), Lanthony desaturated panel D-15 test for color vision, quality of life (QoL), fluorescein and indocyanine green angiography, and optical coherence tomography (OCT).

Results: A significant trend toward a decrease in absolute N1 amplitude values was observed over the follow-up period (P<. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.022DOI Listing
December 2018

National Study of Ocular Hospitalizations in Medicare Beneficiaries.

Am J Ophthalmol 2018 Dec 13. Epub 2018 Dec 13.

Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois USA; Center for Healthcare Studies, Feinberg School of Medicine, Northwestern University, Chicago, Illinois USA; Veterans Affairs Health Services Research and Development Service, Chicago, Illinois USA. Electronic address:

Purpose: To study the characteristics of Medicare Beneficiaries hospitalized for ophthalmic conditions DESIGN: Cross-sectional study METHODS: The 2015 National Medicare 100% Inpatient Limited Dataset was analyzed to identify all patients with either an admitting or primary diagnoses for an ophthalmic condition using ICD-9-CM codes. All other hospitalized Medicare patients served for comparison. Comorbidities were calculated using the Elixhauser Comorbidity Index. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183067
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.12.003DOI Listing
December 2018
2 Reads

Binocular Visual Function with Staged Implantation of Diffractive Multifocal Intraocular Lenses with Three Add Powers.

Am J Ophthalmol 2018 Dec 12. Epub 2018 Dec 12.

Department of Ophthalmology, Tokyo Dental Collage Suidobashi Hospital.

Purpose: To evaluate the binocular visual function and depth of focus after staged implantation of diffractive multifocal intraocular lenses (MIOLs) with three different add powers following cataract removal.

Design: Prospective comparative case series.

Methods: Setting: Institutional. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.020DOI Listing
December 2018

Choroidal microvascular dropout in primary angle closure glaucoma.

Am J Ophthalmol 2018 Dec 12. Epub 2018 Dec 12.

University Eye Clinic Maastricht, University Medical Center, Maastricht, the Netherlands.

Purpose: To determine the prevalence and factors associated with the presence of choroidal microvascular dropout (CMvD) in primary angle-closure glaucoma (PACG) eyes compared to primary open-angle glaucoma (POAG) eyes.

Design: Cross-sectional study METHODS: Thirty-six POAG eyes (36 patients) and 28 PACG eyes (28 patients) underwent optical coherence tomography angiography (OCTA). Presence of CMvD was evaluated on choroidal OCTA slabs. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183066
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.11.021DOI Listing
December 2018
1 Read

Tear Inflammatory Cytokines Analysis and Clinical Correlations in Diabetes and Non-diabetes with Dry Eye.

Am J Ophthalmol 2018 Dec 12. Epub 2018 Dec 12.

Department of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, 100191, China. Electronic address:

Purpose: To enhance the understanding of dry eye (DE) in diabetes by evaluating the ocular surface characteristics and the levels of tear inflammatory cytokines.

Design: Cross-sectional study.

Methods: Subjects were divided into four groups: 32 patients in diabetes with DE group; 24 patients in diabetes without DE group; 28 patients in non-diabetes with DE group and 29 volunteers in normal group. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.12.001DOI Listing
December 2018
1 Read

The Impact of Prefilled Syringes on Endophthalmitis following Intravitreal Injection of Ranibizumab.

Am J Ophthalmol 2018 Dec 12. Epub 2018 Dec 12.

Mid Atlantic Retina, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA. Electronic address:

Purpose: To compare the rates of infectious endophthalmitis following intravitreal injection of ranibizumab using prefilled syringes vs. conventional preparation.

Design: Multicenter, retrospective, cohort study METHODS: All eyes receiving intravitreal injection of 0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.023DOI Listing
December 2018
3.871 Impact Factor

Association of age-related macular degeneration with mortality in patients with AIDS; role of systemic inflammation.

Am J Ophthalmol 2018 Dec 12. Epub 2018 Dec 12.

Department of Medicine, the University of California, San Francisco, School of Medicine, San Francisco, CA, USA.

Purpose: To evaluate the relationships among age-related macular degeneration (AMD), mortality, and biomarkers of systemic inflammation in patients with the acquired immunodeficiency syndrome (AIDS).

Design: Case control study.

Participants: Participants with intermediate-stage AMD at enrollment in the Longitudinal Study of the Ocular Complications of AIDS (LSOCA) and 2:1 controls matched for age and gender. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.12.002DOI Listing
December 2018

Management of invasive squamous cell carcinomas of the conjunctiva Treatment of invasive conjunctival carcinoma.

Am J Ophthalmol 2018 Dec 12. Epub 2018 Dec 12.

Department of Ophthalmology, Pasteur 2 Teaching Hospital, Nice, France.

Purpose: Ocular Surface Squamous Neoplasia includes a spectrum of diseases from dysplasia to invasive squamous cell carcinoma of the conjunctiva. Whether the degree of invasion influences outcomes is debated. We evaluated the outcomes and management of conjunctival carcinomas defined as ≤0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.024DOI Listing
December 2018

Automated Detection of the Stromal Demarcation Line using Optical Coherence Tomography in Keratoconus Eyes after Corneal Crosslinking.

Am J Ophthalmol 2018 Dec 5. Epub 2018 Dec 5.

Department of Ophthalmology, American University of Beirut Medical Center, Beirut, Lebanon; Department of Computer Science, American University of Beirut, Beirut, Lebanon.

Purpose: To evaluate the role of a novel automated detection software as compared to human operators in assessing the presence and depth of stromal demarcation line on optical coherence tomography (OCT) in keratoconus eyes post cross-linking Design: This was a reliability analysis study.

Methods: Two independent operators and an automated detection software examined corneal OCTs of 25 eyes of 25 patients post corneal cross-linking using the Dresden protocol, at 3 months postoperatively. Operators evaluated the presence of the demarcation line and measured its depth by looking at OCT images (128 cuts) on two separate occasions one week apart. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.017DOI Listing
December 2018
1 Read

Endophthalmitis incidence of cancer patients after cataract surgery: A nationwide matched cohort study in Taiwan.

Am J Ophthalmol 2018 Dec 5. Epub 2018 Dec 5.

Department of Public Health, College of Medicine, Chang Gung University, Taiwan; Division of Rheumatology, Allergy, and Immunology, Chang Gung Memorial Hospital at Linkou, Taiwan; Biostatistics Core Laboratory, Molecular Medicine Research Center, Chang Gung University, Taiwan. Electronic address:

Purpose: To compare the incidence rate of endophthalmitis after cataract surgery between cancer cohort and matched non-cancer cohort.

Design: matched cohort study METHODS: Patients with cataract surgery of both eyes among a nationwide cancer cohort and 1:1 matched non-cancer cohort were enrolled from the year of 1998 to 2012 in Taiwan National Health Insurance Research Database. Both the cancer group and the control group were followed for three months after the cataract surgery to obtain the rate of endophthalmitis. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183066
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.11.018DOI Listing
December 2018
3 Reads

Reply.

Am J Ophthalmol 2018 Nov 28. Epub 2018 Nov 28.

Los Angeles, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.10.006DOI Listing
November 2018

Assessment of Circumferential Angle Closure with Swept-Source Optical Coherence Tomography: a community based study.

Am J Ophthalmol 2018 Nov 28. Epub 2018 Nov 28.

Singapore Eye Research Institute, Singapore National Eye Centre. Electronic address:

Purpose: To evaluate the diagnostic performance of swept-source optical coherence tomography (SS-OCT, CASIA SS-1000, Tomey Corporation, Nagoya, Japan) for angle closure detection, in comparison with gonioscopy in a community setting.

Design: Reliability analysis.

Methods: A total of 2027 phakic subjects aged ≥50 years, with no previous history of glaucoma, laser (including peripheral iridotomy), intraocular surgery or ocular trauma, were consecutively recruited from a community polyclinic in Singapore. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.015DOI Listing
November 2018
2 Reads

Changes in Ganglion Cell-Inner Plexiform Layer Thickness and Retinal Microvasculature in Hypertension: An OCT Angiography Study.

Am J Ophthalmol 2018 Nov 28. Epub 2018 Nov 28.

Department of Ophthalmology, Chungnam National University College of Medicine, Daejeon, Republic of Korea. Electronic address:

Objective: To investigate retinal blood flow in patients with hypertension using optical coherence tomography angiography (OCTA) and the relationship between blood flow metrics and ganglion cell-inner plexiform layer (GC-IPL) thickness.

Design: Retrospective, cross-sectional study.

Methods: A total of 201 eyes from 117 healthy subjects and 84 hypertensive patients without any ocular abnormalities were included. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183065
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.11.016DOI Listing
November 2018
3 Reads

International Board Members of the American Journal of Ophthalmology.

Am J Ophthalmol 2018 Nov 28. Epub 2018 Nov 28.

Department of Ophthalmology, Medical University of Gdańsk, Poland.

This year marks the 100th anniversary of the "modern" American Journal of Ophthalmology (AJO). International influence was present since the beginnings of the journal, and AJO had several foreign editorial board members and collaborators. Within the article we present sketches of the deceased international board members of the AJO, particularly of Sir Stewart Duke-Elder, Pierre Amalric, Joaquin Barraquer and Yasuo Tano. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.011DOI Listing
November 2018
1 Read

Clinical and biological factors associated with recurrences of severe toxoplasmic retinochoroiditis confirmed by aqueous humor analysis.

Am J Ophthalmol 2018 Nov 28. Epub 2018 Nov 28.

Ophthalmology Department, Reference Center in Rare diseases, DHU ViewRestore, Pitié-Salpêtrière Hospital, Paris VI University, F-75013 Paris, France.

Purpose: To investigate clinical and biological factors influencing recurrences of severe toxoplasmic retinochoroiditis (TRC) confirmed by aqueous humor analysis.

Design: Retrospective case series.

Methods: Retrospective analysis of 87 subjects with severe TRC, proven by positive Goldmann-Witmer coefficient (GWC), Toxoplasma gondii (T. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.013DOI Listing
November 2018
1 Read

Clinical outcomes of Descemet membrane endothelial keratoplasty in eyes with a glaucoma drainage device.

Am J Ophthalmol 2018 Nov 28. Epub 2018 Nov 28.

Netherlands Institute for Innovative Ocular Surgery (NIIOS), Rotterdam, The Netherlands; Melles Cornea Clinic Rotterdam, The Netherlands; Amnitrans Eye Bank Rotterdam, The Netherlands; NIIOS-USA, San Diego, USA. Electronic address:

Purpose: To evaluate the feasibility and clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) in eyes with a glaucoma drainage device (GDD).

Design: Retrospective, interventional case series.

Methods: Clinical outcomes of 23 DMEK procedures for bullous keratopathy (52%), failed previous transplant (39%) or Fuchs endothelial corneal dystrophy (9%) in 20 eyes (19 patients) with a GDD were retrospectively analyzed at two tertiary referral centers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.014DOI Listing
November 2018
1 Read

Re: Magnetic Resonance Imaging of the Globe-Tendon Interface for Extraocular Muscles: Is There an "Arc of Contact"?

Am J Ophthalmol 2018 Nov 27. Epub 2018 Nov 27.

San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.09.040DOI Listing
November 2018

Macula Vessel Density and Thickness in Early Primary Open Angle Glaucoma.

Am J Ophthalmol 2018 Nov 26. Epub 2018 Nov 26.

Hamilton Glaucoma Center, Shiley Eye Institute, Department of Ophthalmology, University of California, San Diego, CA, United States. Electronic address:

Purpose: To characterize and compare the ganglion cell complex (GCC) thickness and macula vessel density in pre-perimetric and early primary open angle glaucoma (POAG) eyes.

Design: Cross-sectional study.

Methods: 57 healthy eyes, 68 pre-perimetric and 162 early POAG eyes enrolled in the Diagnostic Innovations in Glaucoma Study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.012DOI Listing
November 2018

Argon Laser Photocoagulation For Macular Edema In Branch Vein Occlusion.

Authors:

Am J Ophthalmol 2018 Dec;196:xxx-xxxviii

The Branch Vein Occlusion Study is a multi-center, randomized, controlled clinical trial designed to answer several questions regarding the management of complications of branch vein occlusion. This report discusses the question, "Is argon laser photocoagulation useful in improving visual acuity in eyes with branch vein occlusion and macular edema reducing vision to 20/40 or worse?" One hundred thirty-nine eligible eyes were assigned randomly to either a treated or an untreated control group. Comparing treated patients to control patients (mean follow-up 3. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.09.018DOI Listing
December 2018

Assessment of the Impact of an Endpoint Committee in the Ocular Hypertension Treatment Study.

Am J Ophthalmol 2018 Nov 21. Epub 2018 Nov 21.

Washington University School of Medicine, Department of Ophthalmology and Visual Sciences 660 S. Euclid, Box 8096 Saint Louis, Missouri 63110.

Purpose: To assess the impact of a masked Endpoint Committee on estimates of the incidence of primary open angle glaucoma (POAG), treatment efficacy and statistical power of the Ocular Hypertension Treatment Study-Phase 1, 1994-2002 (OHTS-1).

Design: Retrospective inter-rater reliability analysis of endpoint attribution by the Endpoint Committee METHODS: After study closeout, we re-calculated estimates of endpoint incidence, treatment efficacy and statistical power using all-cause endpoints and POAG endpoints. To avoid bias, only the first endpoint per participant is included in this report. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.006DOI Listing
November 2018
4 Reads

Comparison of topical 5-fluorouracil and interferon alfa-2b as primary treatment modalities for ocular surface squamous neoplasia.

Am J Ophthalmol 2018 Nov 21. Epub 2018 Nov 21.

Bascom Palmer Eye Institute, University of Miami, Miami, Florida, USA. Electronic address:

Purpose: To compare the efficacy of topical 5-fluorouracil 1% (5FU) and interferon alfa-2b 1 MIU/mL (IFN) eye drops as primary treatment modalities for ocular surface squamous neoplasia (OSSN).

Design: Retrospective, comparative, interventional case series.

Methods: Fifty-four patients who received 5FU and 48 patients who received IFN as primary therapy for OSSN were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.007DOI Listing
November 2018
3 Reads

Early Detection of Glaucomatous Visual Field Progression Using Pointwise Linear Regression with Binomial Test in the Central 10 Degrees.

Am J Ophthalmol 2018 Nov 19. Epub 2018 Nov 19.

Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan. Electronic address:

Purpose: We previously reported that it was beneficial to apply binomial pointwise linear regression (PLR) to detect 24-2 glaucomatous visual field (VF) progression, compared to mean deviation (MD) trend analysis and permutation analysis of PLR (PoPLR). The purpose of the current study was to validate the usefulness of the binomial PLR method to detect VF progression in the central 10 degrees in glaucoma patients.

Design: Reliability assessment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.004DOI Listing
November 2018
3 Reads

En Face Optical Coherence Tomography Imaging of the Photoreceptor Layers in Hydroxychloroquine Retinopathy.

Am J Ophthalmol 2018 Nov 15. Epub 2018 Nov 15.

Department of Ophthalmology, Hanyang University Hospital, Hanyang University College of Medicine, Seoul, Republic of Korea. Electronic address:

Objective: To investigate the application of en face optical coherence tomography (OCT) imaging in eyes with hydroxychloroquine (HCQ) retinopathy.

Design: Retrospective case series METHODS: SETTING: Institutional PATIENT POPULATION: Sixty-two eyes of 31 Asian patients with HCQ retinopathy.

Observation Procedures: Macular volume scanning using swept-source OCT was performed in 6 × 6 and 9 × 9 mm areas centered on the fovea. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.003DOI Listing
November 2018
3 Reads

Amniotic Membrane Transplantation in Acute Severe Ocular Chemical Injury: A Randomized Clinical Trial.

Am J Ophthalmol 2018 Nov 9. Epub 2018 Nov 9.

Cincinnati Eye Institute, Edgewood, KY/ University of Cincinnati, Department of Ophthalmology, Cincinnati, OH USA. Electronic address:

Purpose: To compare the outcomes of conventional medical treatment versus combined medical treatment and amniotic membrane transplantation (AMT) in the management of patients with Roper-Hall grade IV ocular chemical injury.

Design: Randomized, parallel-controlled clinical trial METHODS: Setting: Single tertiary referral hospital.

Patients: 60 eyes of 60 patients with Roper-Hall grade IV ocular chemical injury with a minimum follow-up of 12 months were enrolled in the study. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183062
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.11.001DOI Listing
November 2018
8 Reads

Orbital Lymphoma - An International Multicenter Retrospective Study.

Am J Ophthalmol 2018 Nov 9. Epub 2018 Nov 9.

Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Denmark; Department of Pathology, Rigshospitalet, University of Copenhagen, Denmark. Electronic address:

Purpose: To investigate and characterize the clinical features of subtype-specific orbital lymphoma.

Design: Retrospective, interventional case series.

Methods: The study included 7 international eye cancer centers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.11.002DOI Listing
November 2018
2 Reads
3.870 Impact Factor

Glaucoma Specialist Detection of Optical Coherence Tomography Suspicious Rim Tissue in Glaucoma and Glaucoma Suspect Eyes.

Am J Ophthalmol 2018 Nov 7. Epub 2018 Nov 7.

Devers Eye Institute, Optic Nerve Head Research Laboratory, Legacy Research Institute, 1225 NE 2nd Ave, Portland, OR 97208-3950; Devers Eye Institute, Discoveries in Sight Research Laboratories, Legacy Research Institute, 1225 NE 2nd Ave, Portland, OR 97208-3950; Devers Eye Institute Glaucoma Service, 1040 NW 22nd Ave, Portland, OR 97210. Electronic address:

Purpose: To assess glaucoma specialists' detection of optic nerve head (ONH) rim tissue that is thin by optical coherence tomography (OCT) criteria.

Design: Reliability analysis METHODS: 5 clinicians marked the disc margin (DM) and rim margin (RM) on stereo-photos of 151 glaucoma or glaucoma suspect eyes obtained within 3 months of OCT imaging. The photo and OCT infrared image for each eye were colocalized and regionalized into twelve sectors relative to the axis between Bruch's membrane opening (BMO) centroid and the fovea. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183062
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.10.027DOI Listing
November 2018
6 Reads

Incidence and Outcomes of Intraoperative Descemet Membrane Perforations During Deep Anterior Lamellar Keratoplasty.

Am J Ophthalmol 2018 Oct 31. Epub 2018 Oct 31.

Singapore National Eye Centre, Singapore; Singapore Eye Research Institute, Singapore; Ophthalmology Academic Clinical Program, Duke-NUS Graduate Medical School, Singapore; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:

Purpose: To report the incidence and outcomes of intraoperative Descemet membrane (DM) perforations during deep anterior lamellar keratoplasty (DALK).

Design: Retrospective, consecutive, interventional case series.

Methods: A retrospective audit of all DALK cases performed from 2004 to 2015 in a tertiary centre, with and without intraoperative DM perforations. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183062
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.10.026DOI Listing
October 2018
7 Reads

Reply.

Am J Ophthalmol 2019 Jan 31;197:184-185. Epub 2018 Oct 31.

Lexington, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.09.016DOI Listing
January 2019
1 Read

Incorporating Optical Coherence Tomography in the Cataract Preoperative Armamentarium: Additional Need or Additional Burden?

Am J Ophthalmol 2018 Oct 30. Epub 2018 Oct 30.

Visakha Eye Centre, Peddawaltair, Visakhapatnam, India.

Purpose: To determine the usefulness of preoperative OCT examination to detect asymptomatic macular abnormalities in patients scheduled for cataract surgery METHODS: Design: Prospective, interventional case series Setting: Iladevi Cataract and Visakha Eye Center, Ahmedabad, IndiaStudy Population: Patients undergoing cataract surgery and intraocular lens(IOL) implantation for senile cataracts. Preoperatively no retinal/macular pathology was identified on clinical evaluation.

Intervention: All eyes underwent Macular 5-Line Raster evaluation using Spectral Domain OCT before and after cataract surgery(monthly for 3 months). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.10.025DOI Listing
October 2018

Validated Prediction Models for Macular Degeneration Progression and Predictors of Visual Acuity Loss Identify High Risk Individuals.

Am J Ophthalmol 2018 Oct 30. Epub 2018 Oct 30.

Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, Boston, MA.

Purpose: To determine predictive factors and risk scores for conversion to overall advanced age-related macular degeneration (AMD), geographic atrophy (GA), neovascular disease (NV), and loss of vision, and to validate the model for AMD in an external cohort.

Methods: Progression to advanced AMD was evaluated using stepwise survival analysis. Risk scores including genetic, demographic, behavioral, and ocular factors were derived for three AMD endpoints and were validated and calibrated in a large independent cohort. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.10.022DOI Listing
October 2018

Modifications of Callender's Classification of Uveal Melanoma at the Armed Forces Institute of Pathology.

Am J Ophthalmol 2018 Nov;195:lvi-lx

University of Louisville School of Medicine, Louisville, Kentucky.

One hundred well-documented cases of uveal melanoma accessioned at the Armed Forces Institute of Pathology before 1970 were reviewed and reclassified to identify changes made in the Callender classification. We compared the new classification with the original classification to determine the effect of the changes on the prediction of outcome for the patient after enucleation. Staff pathologists had originally classified 52 of the 100 cases as spindle-cell type melanoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.08.025DOI Listing
November 2018
4 Reads

Corrigendum.

Authors:

Am J Ophthalmol 2018 Nov;195:249

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.09.023DOI Listing
November 2018

The Prospective Retrospective Study.

Am J Ophthalmol 2018 Dec 28;196:xiii-xv. Epub 2018 Oct 28.

Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.09.006DOI Listing
December 2018

Reclassifying Idiopathic Uveitis: Lessons from a Tertiary Uveitis Center.

Am J Ophthalmol 2018 Oct 20. Epub 2018 Oct 20.

Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA; Department of Medicine, Oregon Health & Science University, Portland, OR. USA; Legacy Devers Eye Institute, Legacy Health System, Portland, OR. USA. Electronic address:

Purpose: Idiopathic uveitis is frequently the most common diagnosis in series from uveitis clinics. We sought to determine the percentage of patients initially diagnosed as idiopathic, non-infectious uveitis referred to a tertiary uveitis center who were subsequently found to have an identifiable cause of uveitis.

Design: Retrospective case series. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183060
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.10.018DOI Listing
October 2018
4 Reads

Prevalence of normal tension glaucoma in the Chinese population: A systematic review and meta-analysis.

Am J Ophthalmol 2018 Oct 20. Epub 2018 Oct 20.

Department of Ophthalmology, University of California San Francisco, San Francisco Medical School, San Francisco, California, USA. Electronic address:

Purpose: To investigate the prevalence of normal tension glaucoma (NTG) in the Chinese population through systematic review and meta-analysis.

Design: systematic review and meta-analysis.
 MATERIALS AND METHOD: All Chinese population-based studies that reported the prevalence of NTG were identified. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183060
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.10.017DOI Listing
October 2018
5 Reads

Corneal limbal stem cell deficiency in children with Stevens-Johnson syndrome.

Am J Ophthalmol 2018 Oct 19. Epub 2018 Oct 19.

Laboratory of Ocular Regenerative Medicine and Immunology, Seoul Artificial Eye Center, Seoul National University Hospital Biomedical Research Institute, Seoul, Republic of Korea; Department of Ophthalmology, Seoul National University Hospital, Seoul, Republic of Korea. Electronic address:

Purpose: To determine the incidence of corneal limbal stem cell deficiency (LSCD) as chronic ocular sequelae in children with Stevens-Johnson syndrome (SJS) / toxic epidermal necrolysis (TEN) and analyze the factors associated with LSCD development.

Design: Retrospective case series.

Methods: Medical records were reviewed of pediatric patients who had been admitted to Seoul National University Hospital with SJS/TEN and diagnosed as having acute ocular involvement. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183060
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.10.016DOI Listing
October 2018
10 Reads

Incidence of Management Changes at the Postoperative Week One Visit after Cataract Surgery: Results from the PCIOL Study.

Am J Ophthalmol 2018 Oct 16. Epub 2018 Oct 16.

Massachusetts Eye and Ear Infirmary, Boston, MA; Harvard Medical School, Boston, MA. Electronic address:

Purpose: To ascertain the incidence of unexpected management changes at the postoperative week one visit in asymptomatic patients who have had an uncomplicated cataract surgery and a routine postoperative day one examination.

Design: Retrospective observational study METHODS: Retrospective chart review was conducted of all cases of cataract extraction by phacoemulsification with intraocular lens insertion performed by the Comprehensive Ophthalmology Service at Massachusetts Eye and Ear between January 1, 2014 and December 31, 2014. The preoperative consultation, operative report, and postoperative day one and week one (postoperative days 5-14) visits were reviewed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.10.013DOI Listing
October 2018

Using Kalman Filtering to Forecast Disease Trajectory for Patients with Normal Tension Glaucoma.

Am J Ophthalmol 2018 Oct 15. Epub 2018 Oct 15.

Department of Ophthalmology and Visual Sciences, University of Michigan Medical School; Ann Arbor, MI, USA; Center for Eye Policy and Innovation, University of Michigan; Ann Arbor, MI, USA; Department of Health Management and Policy, University of Michigan School of Public Health; Ann Arbor, MI, USA. Electronic address:

Purpose: To determine whether a machine learning technique called Kalman filtering (KF) can accurately forecast future values of mean deviation (MD), pattern standard deviation (PSD), and intraocular pressure (IOP) for patients with normal tension glaucoma (NTG).

Design: Development and testing of a forecasting model for glaucoma progression.

Methods: We parameterized and validated a Kalman filter (KF-NTG) to forecast MD, PSD, and IOP at 24 months into the future using 263 eyes of 263 Japanese patients with NTG. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183059
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.10.012DOI Listing
October 2018
3 Reads

A new SITA perimetric threshold testing algorithm; construction and a multi-center clinical study.

Am J Ophthalmol 2018 Oct 15. Epub 2018 Oct 15.

Department of Clinical Sciences Malmö, Ophthalmology, Lund University and Skåne University Hospital Malmo¨, Sweden.

Purpose: To describe a new time-saving threshold visual field testing strategy, SITA Faster intended to replace SITA Fast and to report on a clinical evaluation of this new strategy.

Design: Description and validity analysis for modifications applied to SITA Fast.

Methods: 5 centers tested one eye of each of 126 glaucoma and glaucoma suspect patients with SITA Faster, SITA Fast and SITA Standard at each of two visits. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183059
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.10.010DOI Listing
October 2018
15 Reads

Ocular and periocular tumors in xeroderma pigmentosum: A study of 120 Asian Indian patients.

Am J Ophthalmol 2018 Oct 15. Epub 2018 Oct 15.

Ophthalmic Pathology Laboratory , L V Prasad Eye Institute, Hyderabad, India.

Purpose: To study the incidence, treatment, and outcome of ocular and periocular tumors in patients with xeroderma pigmentosum (XP) DESIGN: Retrospective case series METHODS: Setting: Single-institutional study PATIENTS: 120 patients with XP INTERVENTION: Excisional biopsy, Enucleation, Orbital exenteration; Main outcome measures: Occurrence of eyelid or ocular surface tumor, globe salvage, locoregional and systemic metastasis, and death RESULTS: The mean age at presentation was 19 years. Family history of XP was present in 32 (27%) patients. Over a mean follow-up of 61 months, 34 (28%) patients developed no ocular/adnexal tumor, 86 (72%) developed ocular surface malignancy, 15 (13%) developed eyelid malignancy, and 22 (18%) developed other head and neck malignancies. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183059
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.10.011DOI Listing
October 2018
11 Reads

Reply.

Am J Ophthalmol 2019 Jan 13;197:182. Epub 2018 Oct 13.

Nottingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.08.046DOI Listing
January 2019
1 Read

Preeclampsia/Eclampsia as a Risk Factor of Non-Infectious Uveitis among Postdelivery Women.

Am J Ophthalmol 2018 Oct 11. Epub 2018 Oct 11.

Department of Ophthalmology, Chang Gung Memorial Hospital, Chiayi, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan. Electronic address:

Purpose: To analyze the incidence and risk of non-infectious uveitis among postdelivery women with a history of preeclampsia/eclampsia.

Design: Population-based retrospective matched cohort study. Methods SETTING: All participant data were retrieved from the Longitudinal Health Insurance Database 2005 STUDY POPULATION: 2073 postdelivery women, aged ≥20 years, diagnosed with preeclampsia/eclampsia were included from January 1, 1997 to December 31, 2012. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2018.10.009DOI Listing
October 2018
3 Reads

Using Deep Learning and transform learning to accurately diagnose early-onset glaucoma from macular optical coherence tomography images.

Am J Ophthalmol 2018 Oct 11. Epub 2018 Oct 11.

Kanto Central Hospital of the Mutual Aid Association of Public School Teachers, Tokyo, Japan.

Purpose: To construct and evaluate a Deep Learning (DL) model to diagnose early glaucoma from spectral domain optical coherence tomography (SD-OCT) images.

Design: AI diagnostic tool development, evaluation, and comparison METHODS: Setting: multiple institutional practices.

Study Population: Pre-training data consisted of 4316 OCT images (RS3000, Nidek) from 1565 eyes with open angle glaucoma (OAG) irrespective of the stage of glaucoma and 193 normal eyes. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029394183058
Publisher Site
http://dx.doi.org/10.1016/j.ajo.2018.10.007DOI Listing
October 2018
1 Read