Am J Obstet Gynecol 2017 Dec 22. Epub 2017 Dec 22.
Mothers and Babies Research Centre, Hunter Medical Research Institute, University of Newcastle, New Lambton Heights, Callaghan, New South Wales, Australia; School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales, Australia; Priority Research Centre in Reproductive Science, Faculty of Health and Medicine, Callaghan, New South Wales, Australia. Electronic address:
The placenta ages as pregnancy advances, yet its continued function is required for a successful pregnancy outcome. Placental aging is a physiological phenomenon; however, there are some placentas that show signs of aging earlier than others. Premature placental senescence and aging are implicated in a number of adverse pregnancy outcomes, including fetal growth restriction, preeclampsia, spontaneous preterm birth, and intrauterine fetal death. Read More