40,136 results match your criteria American journal of obstetrics and gynecology[Journal]


September 2018 (vol. 219, no. 3, page 301.e10).

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Am J Obstet Gynecol 2019 Feb 19. Epub 2019 Feb 19.

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http://dx.doi.org/10.1016/j.ajog.2019.01.007DOI Listing
February 2019

Letter to the Editor: Defining 17OHP-C responsiveness.

Am J Obstet Gynecol 2019 Feb 18. Epub 2019 Feb 18.

Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.

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http://dx.doi.org/10.1016/j.ajog.2019.02.032DOI Listing
February 2019

Influence of periconception smoking behavior on birth defect risk.

Am J Obstet Gynecol 2019 Feb 18. Epub 2019 Feb 18.

Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Cincinnati, Ohio; Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. Electronic address:

Background: Smoking is one of the most modifiable risk factors for adverse maternal and neonatal outcome. Smoking during pregnancy has been associated with fetal growth restriction, adverse pregnancy outcomes and chronic adult diseases. Existing research has evaluated the risk of smoking on congenital defects. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.029DOI Listing
February 2019

A Randomized Controlled Trial of Dilapan-S versus Foley Balloon for Pre-induction Cervical Ripening (DILAFOL Trial).

Am J Obstet Gynecol 2019 Jan 14. Epub 2019 Jan 14.

Department of Obstetrics & Gynecology, the University of Texas Medical Branch at Galveston, TX, USA.

Objective: To test the hypothesis that Dilapan-S is non-inferior to the Foley balloon for pre-induction cervical ripening at term.

Methods: Pregnant women > 37 weeks scheduled for induction with unfavorable cervix (≤ 3cm dilated and ≤ 60% effaced) were randomly assigned to 12 hours of either Foley balloon (FB) inflated with 60 cc saline or Dilapan-S (DS) for cervical ripening. If the cervix remained unfavorable, then one more round of the assigned dilator was used. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.008DOI Listing
January 2019

Immune Tolerance Attenuates Gut Dysbiosis, Dysregulated Uterine Gene Expression and High-Fat Diet Potentiated Preterm Birth in Mice.

Am J Obstet Gynecol 2019 Feb 18. Epub 2019 Feb 18.

Department of Pharmaceutical Sciences, St. John's University, Queens, NY; Departments of Pathology and Obstetrics & Gynecology and Women's Health and Medicine, Albert Einstein College of Medicine, Bronx, NY.

Background: Preterm delivery is associated with 85% of perinatal morbidity and mortality. While consumption of a high-fat diet leads to exaggerated pro-inflammatory responses and, in pregnant women, increased rates of spontaneous preterm birth, the underlying mechanisms remain unclear.

Objective: We sought to elucidate the mechanisms by which maternal consumption of a high fat diet leads to a dysregulated immune response and, in turn, spontaneous preterm birth. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.028DOI Listing
February 2019

Letter to the Editor: Defining the clinical response to 17-alpha hydroxyprogesterone caproate.

Am J Obstet Gynecol 2019 Feb 18. Epub 2019 Feb 18.

Department of Obstetrics, Gynecology and Reproductive Sciences; Division of Maternal-Fetal Medicine; Magee-Womens Hospital of the University of Pittsburgh.

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http://dx.doi.org/10.1016/j.ajog.2019.02.031DOI Listing
February 2019

A Contemporary Amniotic Fluid Volume Chart for the United States: The NICHD Fetal Growth Studies-Singletons.

Am J Obstet Gynecol 2019 Feb 18. Epub 2019 Feb 18.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.

Background: Amniotic fluid is essential to normal fetal development and is estimated clinically with ultrasound to identify pregnancies at risk for poor perinatal outcome, OBJECTIVES: Our goal was to develop a United States standard for amniotic fluid volume estimated by the amniotic fluid index and single deepest pocket.

Study Design: We performed a planned secondary analysis of a multicenter observational study of 2334 low-risk women with normal singleton gestations from one of 4 self-reported racial-ethnic groups. Eligible women had confirmed first-trimester dating criteria with health status, lifestyles and medical and obstetric histories associated with normal fetal growth. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.030DOI Listing
February 2019

Assessing Research Gaps and Unmet Needs in Endometriosis.

Am J Obstet Gynecol 2019 Feb 18. Epub 2019 Feb 18.

Society for Women's Health Research, Washington, DC, USA. Electronic address:

Endometriosis, a systemic disease that is often painful and chronic, affects ∼10% of reproductive-age women. The disease can negatively impact a patient's physical and emotional well-being, quality of life, and productivity. Endometriosis also places significant economic and social burden on patients, their families, and society as a whole. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.033DOI Listing
February 2019

Delivery-associated sepsis: trends in prevalence and mortality.

Am J Obstet Gynecol 2019 Feb 13. Epub 2019 Feb 13.

Department of Obstetrics and Gynecology, Morsani College of Medicine, University of South Florida, Tampa, FL.

Background: Sepsis is a leading cause of pregnancy-related mortality. Previous studies have reported an increased prevalence of sepsis during pregnancy. Despite national campaigns to increase sepsis awareness, there is a lack of pregnancy-specific guidelines. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029378193032
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http://dx.doi.org/10.1016/j.ajog.2019.02.002DOI Listing
February 2019
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4.704 Impact Factor

Unexpected term NICU admissions: a marker of obstetrical care quality?

Am J Obstet Gynecol 2019 Feb 13. Epub 2019 Feb 13.

Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA; Department of Pediatrics, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Harvard University, Boston, MA.

Background: Unexpected admissions of term neonates to the neonatal intensive care unit (NICU) and unexpected postnatal complications have been proposed as neonatal-focused quality metrics for intrapartum care. Previous studies have noted significant variation in overall hospital NICU admission rates; however, little is known about the influence of obstetric practices on these rates or whether variation among unanticipated admissions in low risk, term neonates can be attributed to systemic hospital practices.

Objective: To examine the relative effects of patient characteristics and intrapartum events on unexpected NICU admissions, and to quantify the between-hospital variation in NICU admission rates among this group of neonates. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029378193032
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http://dx.doi.org/10.1016/j.ajog.2019.02.001DOI Listing
February 2019
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Maternal Outcomes by Race during Postpartum Readmissions.

Am J Obstet Gynecol 2019 Feb 13. Epub 2019 Feb 13.

Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, NY. Electronic address:

Background: Maternal race may be an important risk factor for postpartum readmissions and associated adverse outcomes.

Objective: To determine the association of race with serious complications during postpartum readmissions.

Study Design: This repeated cross sectional analysis utilized the National (Nationwide) Inpatient Sample from the Healthcare Cost and Utilization Project from 2012 to 2014. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.016DOI Listing
February 2019

Delayed Clamping Versus Milking of Umbilical Cord in Preterm Infants: A Randomized Controlled Trial.

Am J Obstet Gynecol 2019 Feb 5. Epub 2019 Feb 5.

Department of Obstetrics and Gynecology, TriHealth, Cincinnati, OH.

Background: It has been established that delayed umbilical cord clamping in preterm infants results in improvement in neonatal anemia, need for transfusion, incidence of necrotizing enterocolitis, and intraventricular hemorrhage by increasing neonatal circulating blood volume. However, the effects of umbilical cord milking as an alternative to delayed clamping in preterm infants are unclear.

Objective: The primary objective of this study was to compare the effect of delayed clamping versus milking of the umbilical cord on the initial hematocrit concentration in preterm births (23-34 weeks). Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.234DOI Listing
February 2019

Obesity and Laboratory Aspirin Resistance in High Risk Pregnant Women Treated with Low Dose Aspirin.

Am J Obstet Gynecol 2019 Jan 29. Epub 2019 Jan 29.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, OH.

Background: Low dose aspirin (LDA) is used for preeclampsia (PE) prevention in high risk women, but the precise mechanism and optimal dose is unknown. Evidence suggests that an imbalance in prostacyclin and thromboxane A (TXA) plays a key role in the pathogenesis of PE. Aspirin has a dose-dependent effect blocking production of TXA, a potent stimulator of platelet aggregation and promoter of vasoconstriction. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.222DOI Listing
January 2019

The defamation of Ignaz Philipp Semmelweis.

Authors:
Nicholas Kadar

Am J Obstet Gynecol 2019 Feb 16. Epub 2019 Feb 16.

11 Jackson Court, Cranbury, NJ 08512.

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http://dx.doi.org/10.1016/j.ajog.2019.02.026DOI Listing
February 2019

Development and Validation of a Risk-Calculator for Adverse Perioperative Outcomes for Women with Ovarian Cancer.

Am J Obstet Gynecol 2019 Feb 13. Epub 2019 Feb 13.

Columbia University College of Physicians and Surgeons; Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons; New York Presbyterian Hospital. Electronic address:

Background: Primary cytoreduction followed by platinum based chemotherapy is the primary treatment for advanced ovarian cancer. However neoadjuvant chemotherapy followed by interval debulking is an alternative option, particularly in those who may be poor surgical candidates.

Objective: The objective of this study was to determine factors associated with short term, significant perioperative morbidity and mortality for women undergoing surgery for ovarian cancer and to create a nomogram to predict the risk of adverse perioperative outcomes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029378193036
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http://dx.doi.org/10.1016/j.ajog.2019.02.019DOI Listing
February 2019
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Bicentennial of Semmelweis's birth.

Am J Obstet Gynecol 2019 Feb 13. Epub 2019 Feb 13.

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http://dx.doi.org/10.1016/j.ajog.2019.02.024DOI Listing
February 2019

Gynecologic Cancer in HIV-Positive Women: a Systematic Review and Meta-analysis.

Am J Obstet Gynecol 2019 Feb 13. Epub 2019 Feb 13.

Department of Gynecology and Obstetrics, Johns Hopkins School of Medicine, Baltimore, MD; The Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics, Johns Hopkins School of Medicine, Baltimore, MD. Electronic address:

Objective: While there is a significant body of literature on cervical cancer in HIV-positive women, little is known about other gynecologic cancers in this population. The objective of this systematic review and meta-analysis is to describe the incidence, presentation, treatment, and outcomes for HIV-positive women with non-AIDS-defining gynecologic cancers.

Data Source: We searched Medline, Embase, ClinicalTrials. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.022DOI Listing
February 2019
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Unaccounted factors for Opioid Use after Vaginal Delivery.

Authors:
Daniel Fullin

Am J Obstet Gynecol 2019 Feb 13. Epub 2019 Feb 13.

Department of Anesthesiology, Rhode Island Hospital, The Warren, Alpert Medical School of Brown University, Providence, Rhode Island, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2019.02.021DOI Listing
February 2019

Reply to Letter # L19-004AR1.

Am J Obstet Gynecol 2019 Feb 13. Epub 2019 Feb 13.

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Northwestern, University Feinberg School of Medicine, Chicago, IL.

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http://dx.doi.org/10.1016/j.ajog.2019.02.020DOI Listing
February 2019

Rediscovering Ignaz Philipp Semmelweis: Some additional thoughts.

Authors:
Jordan H Perlow

Am J Obstet Gynecol 2019 Feb 13. Epub 2019 Feb 13.

Clinical Professor: University of Arizona College of Medicine - Phoenix; Division of Maternal-Fetal Medicine, Banner University Medical Center - Phoenix; Partner: Phoenix Perinatal Associates.

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http://dx.doi.org/10.1016/j.ajog.2019.02.025DOI Listing
February 2019

Comment on Semmelweis editorial.

Authors:
Tom McFarlane

Am J Obstet Gynecol 2019 Feb 13. Epub 2019 Feb 13.

Stepping Hill Hospital, Didsbury, England. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2019.02.023DOI Listing
February 2019

Increased the risk of osteoporosis with hysterectomy: A longitudinal follow-up study using a national sample cohort.

Am J Obstet Gynecol 2019 Feb 12. Epub 2019 Feb 12.

Department of Obstetrics and Gynecology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Republic of Korea. Electronic address:

Background: Premenopausal hysterectomy is associated with a decreased ovarian reserve, follicular atresia, and subsequently reduced long-term estrogen secretion. Therefore, women who undergo hysterectomy will experience greater gradual bone mineral loss than women with an intact uterus and have an increased risk of osteoporosis.

Objective: This study aimed to evaluate the association between hysterectomy without/with bilateral oophorectomy (BO) and the occurrence of osteoporosis using a national sample cohort from South Korea. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.018DOI Listing
February 2019
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Induction of Labor at 39 Weeks of Gestation vs. Expectant Management for Low-Risk Nulliparous Women: A Cost-Effectiveness Analysis.

Am J Obstet Gynecol 2019 Feb 12. Epub 2019 Feb 12.

Oregon Health & Science University, Department of Obstetrics and Gynecology. Portland, OR.

Background: A large, recent multicenter trial found that induction of labor at 39 weeks for low-risk nulliparous women was not associated with an increased risk of cesarean delivery or adverse neonatal outcomes.

Objective: We sought to examine the cost-effectiveness and outcomes associated with induction of labor at 39 weeks versus expectant management for low-risk nulliparous women in the United States.

Study Design: A cost-effectiveness model using TreeAge software was designed to compare outcomes in women who were induced at 39 weeks versus expectantly managed. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.017DOI Listing
February 2019
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Cluster Randomized Trial of a Patient-Centered Contraceptive Decision Support Tool, My Birth Control.

Am J Obstet Gynecol 2019 Feb 11. Epub 2019 Feb 11.

Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco; Department of Epidemiology & Biostatistics, University of California, San Francisco.

Background: Research suggests the need for improvement in the patient-centeredness and comprehensiveness of contraceptive counseling. My Birth Control is a tablet-based decision support tool designed to improve women's experience of contraceptive counseling and to help them select contraceptive methods that are consistent with their values and preferences.

Objective: The objective of this study was to evaluate the effect of My Birth Control on contraceptive continuation, experience of contraceptive care, and decision quality. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.015DOI Listing
February 2019
2 Reads

Waist circumference in relation to outcomes of infertility treatment with assisted reproductive technologies.

Am J Obstet Gynecol 2019 Feb 11. Epub 2019 Feb 11.

Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. Electronic address:

Background: Many studies have documented lower likelihood of live birth with increasing body mass index (BMI) among women undergoing assisted reproductive technologies (ART), but few have examined the association with waist circumference (WC), an anthropometric measure that allows assessment of central adiposity.

Objective(s): To examine the relation between baseline WC and infertility treatment outcomes among women undergoing treatment with ART.

Study Design: We followed 264 women who underwent 445 ART cycles for infertility treatment at the Massachusetts General Hospital between 2010 and 2017. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.013DOI Listing
February 2019
2 Reads

Risk factors for surgical intervention of early medical abortion.

Am J Obstet Gynecol 2019 Feb 11. Epub 2019 Feb 11.

Department of Gynaecology, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 9, 2100 Copenhagen, Denmark.

Background: By being non-invasive, medical termination of pregnancy has increased worldwide access to abortion and improved safety of unsafe abortion. However, secondary surgical intervention is the most frequent complication to medical abortion.

Objective: We aimed to identify and quantify risk factors for surgical intervention in women undergoing medically induced termination of pregnancy before nine completed weeks of gestation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029378193035
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http://dx.doi.org/10.1016/j.ajog.2019.02.014DOI Listing
February 2019
3 Reads

Life-Threatening Complications among Women with Severe Ovarian Hyperstimulation Syndrome.

Am J Obstet Gynecol 2019 Feb 8. Epub 2019 Feb 8.

Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Columbia University Medical Center, 5 Columbus Circle, PH, New York, NY 10019.

Background: Ovarian hyperstimulation syndrome (OHSS) is a potentially life-threatening clinical condition.

Objective: The objective of this study was to evaluate risk factors for life-threatening complications for patients with severe OHSS in a United States nationwide sample.

Materials And Methods: OHSS admissions from 2002-2011 from the Nationwide Inpatient Sample (NIS) were included in this study. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.009DOI Listing
February 2019
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An instrument which addresses the expectations of pregnant women over childbirth.

Am J Obstet Gynecol 2019 Feb 8. Epub 2019 Feb 8.

Postgraduate Program in Health Sciences. University of Southern Santa Catarina at Tubarão, Santa Catarina, Brazil.

Recently, an article published in this Journal concluded that practices which precede childbirth and postpartum can enhance the childbirth experience, as well as the pregnant mother's and family's satisfaction. This study encouraged us to contribute to the debate about the development of strategies to improve childbirth experience. An instrument that measures the expectation of the pregnant women may be a tool that reduces the number of unnecessary cesarean sections and that aid in the adequate delivery, after all each woman is different, bears different expectations, thereby each delivery is also different. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.005DOI Listing
February 2019
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Twin-twin transfusion syndrome: Need for mechanistic studies.

Am J Obstet Gynecol 2019 Feb 8. Epub 2019 Feb 8.

Department of Clinical Chemistry Hematology and Immunology, Diakonessenhuis, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.ajog.2019.02.007DOI Listing
February 2019
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Dietary Patterns and Outcomes of Assisted Reproduction.

Am J Obstet Gynecol 2019 Feb 8. Epub 2019 Feb 8.

Department of Nutrition, Harvard T.H. Chan School of Public Health, 655 Huntington Avenue, Boston, MA 02115; Department of Epidemiology, Harvard T.H. Chan School of Public Health, 655 Huntington Avenue, Boston, MA 02115; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115.

Background: There is growing acceptance that nutrition may be related to fertility, and specifically to ART success in women; however, there is still no specific dietary guidance.

Objective: To evaluate the relationship between pre-treatment adherence to various dietary patterns and outcomes of assisted reproductive technologies (ART).

Study Design: We followed 357 women enrolled in the prospective Environment and Reproductive Health (EARTH) Study, who underwent 608 ART cycles (2007-2017). Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.004DOI Listing
February 2019
2 Reads

Reply to: Twin-twin transfusion syndrome: Need for mechanistic studies.

Am J Obstet Gynecol 2019 Feb 8. Epub 2019 Feb 8.

Centre for Women's & Children Health, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, B15 2TT, UK; West Midlands Fetal Medicine Centre, Birmingham Women's and Children's NHS Foundation Trust, Mindelsohn Way, Edgbaston, B15 2TG, UK.

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http://dx.doi.org/10.1016/j.ajog.2019.02.008DOI Listing
February 2019

Severe cardiovascular morbidity in women with hypertensive diseases during delivery hospitalization.

Am J Obstet Gynecol 2019 Feb 8. Epub 2019 Feb 8.

New Haven CT, Yale School of Medicine.

Background: Cardiovascular disease (CVD) is the leading cause of pregnancy-related death in the United States. (1) Identification of short-term indicators of cardiovascular morbidity has the potential to alter the course of this devastating disease among women. It has been established that hypertensive disorders of pregnancy (HDP) are associated with increased risk of cardiovascular disease 10-30 years after delivery; however, little is known about the association of hypertensive disorders of pregnancy with cardiovascular (CV) morbidity during the delivery hospitalization. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.010DOI Listing
February 2019
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The Unforeseen Psychological, Behavioral and Physiological Complications Associated with Intra Uterine Device use Contraceptions.

Am J Obstet Gynecol 2019 Feb 8. Epub 2019 Feb 8.

Indian Institute of Science Education and Research Bhopal, India. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2019.02.006DOI Listing
February 2019

Reply to Reply to: The Unforeseen Psychological, Behavioral and Physiological Complications Associated with Intra Uterine Device use Contraceptions.

Am J Obstet Gynecol 2019 Feb 8. Epub 2019 Feb 8.

Nemours/A.I. duPont Hospital for Children, Wilmington, DE; Division of Adolescent Medicine and Pediatric Gynecology, Department of Pediatrics, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA; Department of Obstetrics & Gynecology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.ajog.2019.02.003DOI Listing
February 2019

Prediction of Imminent Preeclampsia at 35-37 Weeks' Gestation.

Am J Obstet Gynecol 2019 Feb 7. Epub 2019 Feb 7.

Harris Birthright Research Centre for Fetal Medicine, King's College, London, UK. Electronic address:

Background: In the weeks preceding the clinical onset of preeclampsia (PE) the maternal serum level of the angiogenic placental growth factor (PLGF) is decreased and that of the antiangiogenic factor soluble fms-like tyrosine kinase-1 (sFLT) is increased. Women presenting at specialist clinics with signs or symptoms of hypertensive disorders have been stratified according to concentrations of PLGF or the ratio of concentrations of sFLT and PLGF to determine clinical management for the subsequent 1-4 weeks. An alternative approach for the prediction of PE is use of the competing risks model, a Bayes' theorem based method, to derive patient-specific risk for PE by various combinations of maternal characteristics and medical history with multiples of the median (MoM) values of biomarkers. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.235DOI Listing
February 2019
6 Reads

Society for Maternal-Fetal Medicine (SMFM) Consult Series #48: Immediate postpartum long-acting reversible contraception for women at high-risk for medical complications.

Am J Obstet Gynecol 2019 Feb 7. Epub 2019 Feb 7.

Reproductive planning is important for all women but essential for those with complex health conditions or at high-risk for complications. Pregnancy planning can allow these high-risk women the opportunity to receive preconception counseling, medication adjustment, and risk assessment related to health conditions that directly impact maternal morbidity and mortality risk. Despite the need for pregnancy planning, medically complex women face barriers to contraceptive use, including systemic barriers, such as underinsurance for women at increased risk for complex medical conditions as well as low uptake of effective postpartum contraception. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.011DOI Listing
February 2019
1 Read

Behind the Times: Revisiting Endometriosis and Race.

Am J Obstet Gynecol 2019 Feb 6. Epub 2019 Feb 6.

Ottawa Hospital Research Institute; University of Ottawa, Department of Obstetrics and Gynecology.

Endometriosis is a common gynecologic condition, affecting approximately 10% of reproductive aged women. It commonly presents with pelvic pain, painful periods, and infertility and can significantly impact one's quality of life. Early exploration into the pathophysiology of this condition identified race as a risk factor for endometriosis, with the condition predominantly identified in white women. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.238DOI Listing
February 2019
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Preeclampsia: the role of persistent endothelial cells in uteroplacental arteries.

Am J Obstet Gynecol 2019 Feb 6. Epub 2019 Feb 6.

Department of Gynecology, Obstetrics and Urology, Sapienza, University of Rome, Rome, Italy.

We explore the potential role of the endothelial lining of uteroplacental arteries in the pathogenesis of preeclampsia, a severe pregnancy disorder characterized by incomplete invasion of the uterine vasculature by extravillous trophoblast and angiogenic imbalance. In normal pregnancy, the endothelium disappears progressively from the uteroplacental arteries and is replaced by trophoblast and deposition of fibro-fibrinoid structure, underpinning the so-called physiological transformation of uterine spiral arteries. We hypothesize that partial persistence of the endothelium, albeit injured, initiates a chain of events leading to the emergence of preeclampsia in three sequential stages. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.239DOI Listing
February 2019
2 Reads

Vaginal Ureaplasma parvum serovars and spontaneous preterm birth.

Am J Obstet Gynecol 2019 Feb 5. Epub 2019 Feb 5.

Division of Neonatology, Pediatric Intensive Care and Neuropediatrics, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.

Background: Ureaplasma species (spp.) are the bacteria most often isolated from the amniotic cavity of women with preterm labor or preterm premature rupture of membranes, thus, the link between intrauterine Ureaplasma spp. infection and adverse pregnancy outcome is clearly established. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.237DOI Listing
February 2019
1 Read
4.704 Impact Factor

Factors that affect ultrasound-determined labor progress in women undergoing induction of labor.

Am J Obstet Gynecol 2019 Feb 5. Epub 2019 Feb 5.

Department of Obstetrics and Gynaecology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR. Electronic address:

Background: The traditional approach to assessing labor progress is by digital vaginal examination, however, it is subjective and imprecise. Recent studies have investigated the role of transperineal ultrasonographic assessment of fetal head descent by measuring angle of progression and head-perineum distance.

Objective: The objective of this study was to evaluate factors that affected labor progress, defined by the transperineal ultrasonographic parameters, in women achieving vaginal delivery. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.236DOI Listing
February 2019
1 Read

September 2018 (vol. 219, no. 3, page 243).

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Am J Obstet Gynecol 2019 Feb 4. Epub 2019 Feb 4.

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http://dx.doi.org/10.1016/j.ajog.2018.12.024DOI Listing
February 2019

September 2018 (vol. 219, no. 3, pages 303.e1 and 303.e6).

Authors:

Am J Obstet Gynecol 2019 Feb 4. Epub 2019 Feb 4.

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http://dx.doi.org/10.1016/j.ajog.2018.12.029DOI Listing
February 2019

Prevalence and main outcomes of placenta accreta spectrum: a systematic review and metaanalysis.

Am J Obstet Gynecol 2019 Feb 1. Epub 2019 Feb 1.

Department of Obstetrics, Rigshospitalet, University of Copenhagen, Denmark.

Objective: The objective of this study was to evaluate the prevalence of placenta accreta spectrum in general population studies and the main maternal outcomes at delivery.

Study Design: Data sources: We searched PubMed, Google Scholar, clinicalTrials.gov and MEDLINE between 1982 and 2018. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.233DOI Listing
February 2019
1 Read

Are Prediction Models for Vaginal Birth After Cesarean Accurate?

Am J Obstet Gynecol 2019 Feb 1. Epub 2019 Feb 1.

Department of Obstetrics and Gynecology, Duke University Health System, Durham, North Carolina.

Background: The use of trial of labor after Cesarean (TOLAC) calculators in the prediction of successful vaginal birth after Cesarean (VBAC) gives physicians an evidence-based tool to assist with patient counseling and risk stratification. Prior to deploying prediction models for routine care at an institutional level, it is recommended to initially test their performance in the institution's target population. This allows the institution to understand not only the overall accuracy of the model for the intended population but also to comprehend where the accuracy of the model is most limited when predicting across the range of predictions (calibration). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029378193028
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http://dx.doi.org/10.1016/j.ajog.2019.01.232DOI Listing
February 2019
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Maternal and Newborn Outcomes with Elective Induction of Labor at Term.

Am J Obstet Gynecol 2019 Jan 29. Epub 2019 Jan 29.

Department of Obstetrics & Gynecology, Oregon Health & Science University.

Background: A growing body of evidence supports improved or not worsened birth outcomes with non-medically indicated induction of labor at 39 weeks compared to expectant management. This evidence includes two recent randomized control trials. However, concern has been raised as to whether these studies are applicable to a broader US pregnant population. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.223DOI Listing
January 2019
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Are Fibroid and Bony Pelvis Characteristics Associated with Urinary and Pelvic Symptom Severity?

Am J Obstet Gynecol 2019 Jan 31. Epub 2019 Jan 31.

Department of Obstetrics & Gynecology, Stanford University School of Medicine. Electronic address:

Background: Urinary and pelvic floor symptoms are often attributed to size and location of uterine fibroids. However, direct supporting evidence linking increased size to worsening symptoms is scant and limited to ultrasound evaluation of fibroids. Because management of fibroids is targeted towards symptomatic relief, identification of fibroid and pelvic characteristics associated with worse symptoms is vital to optimizing therapies and preventing needless interventions. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.230DOI Listing
January 2019
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The One Step approach for diagnosing gestational diabetes is associated with better perinatal outcomes than using the Two Step approach: Evidence of Randomized Clinical Trials.

Am J Obstet Gynecol 2019 Jan 31. Epub 2019 Jan 31.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Einstein HealthCare Network, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.ajog.2019.01.231DOI Listing
January 2019
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4.704 Impact Factor

Increased Risk of Incident Chronic Medical Conditions in Infertile Women: Analysis of Us Claims Data.

Am J Obstet Gynecol 2019 Jan 30. Epub 2019 Jan 30.

Department of Urology, Stanford University School of Medicine, Stanford, California.

Background: The risk of common chronic medical conditions among infertile women is not known.

Objective: To study the association between female infertility and risk of incident chronic disease.

Study Design: Retrospective cohort analysis using the Optum® de-identified Clinformatics© Datamart from 2003-2016. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029378193024
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http://dx.doi.org/10.1016/j.ajog.2019.01.214DOI Listing
January 2019
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Deregulation of miR-324/Kiss1/kisspeptin in early ectopic pregnancy: Mechanistic findings with clinical and diagnostic implications.

Am J Obstet Gynecol 2019 Jan 29. Epub 2019 Jan 29.

Instituto Maimónides de Investigación Biomédica de Cordoba (IMIBIC); Department of Cell Biology, Physiology and Immunology, University of Cordoba; Hospital Universitario Reina Sofia; CIBER Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Cordoba, Spain; Institute of Biomedicine, University of Turku, Turku, Finland. Electronic address:

Background: Ectopic pregnancy (EP) is a life-threatening condition, for which novel screening tools enabling early accurate diagnosis would improve clinical outcomes. Kisspeptins, encoded by KISS1, play an essential role in human reproduction, at least partially by regulating placental function and possibly embryo implantation. Kisspeptin levels are massively elevated in normal pregnancy and reportedly altered in various gestational pathologies. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029378193028
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http://dx.doi.org/10.1016/j.ajog.2019.01.228DOI Listing
January 2019
3 Reads