40,892 results match your criteria American journal of obstetrics and gynecology[Journal]


The role of a cytokine storm in severe COVID-19 disease in pregnancy.

Am J Obstet Gynecol 2020 Jul 10. Epub 2020 Jul 10.

Affiliated Xiaolan Hospital, Southern Medical University, No. 65, Jucheng Road. Zhongshan, 528415, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2020.07.010DOI Listing

Episiotomy-site clear cell carcinoma.

Am J Obstet Gynecol 2020 Jul 9. Epub 2020 Jul 9.

Department of Radiology, Instituto Oncologico Fundacion Arturo Lopez Perez, Santiago, Chile.

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http://dx.doi.org/10.1016/j.ajog.2020.07.006DOI Listing

Perioperative opioid prescriptions associated with stress incontinence and pelvic organ prolapse surgery.

Am J Obstet Gynecol 2020 Jul 9. Epub 2020 Jul 9.

Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill,; Center for Women's Health Research, University of North Carolina at Chapel Hill, Chapel Hill, NC.

Background: There is an opioid epidemic in the United States with a contributing factor being opioids prescribed for post-operative pain following surgery.

Objectives: Among women who underwent stress incontinence and pelvic organ prolapse surgeries, our primary objective was to determine the proportion of women who filled perioperative opioid prescriptions and to compare factors associated with these opioid prescriptions. We also sought to assess the risk of prolonged opioid use through one year after SUI and POP surgery. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.07.004DOI Listing

Prevalence of Inadequate and Excessive Iodine Intake in a US Pregnancy Cohort.

Am J Obstet Gynecol 2020 Jul 9. Epub 2020 Jul 9.

Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI; Department of Pediatrics and Human Development, Michigan State University, East Lasing, MI.

Background: US iodine intake, estimated from the median urinary iodine concentration of population representative data, has declined by half since the 1970s which is problematic because maternal iodine intake is critical for fetal neurodevelopment. Relying on median urinary concentrations to assess iodine intake of populations is standard practice but does not describe the number of individuals with insufficient intake. Prevalence estimates of inadequate and excessive intake are better for informing public health applications but require multiple urine samples per person; such estimates have been generated in pediatric populations but not yet among pregnant women. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.052DOI Listing

Single- versus multiple-unit transfusion in hemodynamically stable postpartum anemia: a pragmatic randomized, controlled trial.

Am J Obstet Gynecol 2020 Jul 8. Epub 2020 Jul 8.

Maternal and Child Health Research Center, Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

Background: The American Academy of Blood Banks recommends single-unit red cell transfusion protocols across medicine to reduce transfusion complications and use of a scarce resource. There is minimal data regarding single-unit protocols within obstetrics.

Objective: We aimed to compare a single- vs. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.07.007DOI Listing

Validation of an enhanced recovery after surgery protocol in gynecological surgery: an Italian randomized study.

Am J Obstet Gynecol 2020 Jul 8. Epub 2020 Jul 8.

Department of Obstetrics and Gynecology, University of Brescia, Brescia Italy.

Objective: The study aims to validate an enhanced recovery after surgery (ERAS) protocol in gynecological surgery both for benign and malignant disease (endometrial cancer and advanced ovarian cancer) and to measure the adherence to ERAS items in a randomized trial setting.

Study Design: In this trial (NCT03347409), we randomly assigned patients to undergo standard perioperative care or ERAS protocol. The primary outcome is a shorter length of stay in favor of ERAS. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.07.003DOI Listing

Long-term outcome of postmenopausal women with proliferative endometrium on endometrial sampling.

Am J Obstet Gynecol 2020 Jul 5. Epub 2020 Jul 5.

Introduction: Proliferative endometrium has been reported in 15% of endometrial biopsies of women 50 and older. In contrary to endometrial hyperplasia, proliferative endometrium has not been associated with risk of endometrial cancer. We sought to report on the long-term outcome of postmenopausal women diagnosed with proliferative endometrium. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.045DOI Listing

Homelessness, housing instability, and abortion outcomes at an urban US abortion clinic.

Am J Obstet Gynecol 2020 Jul 5. Epub 2020 Jul 5.

University of California San Francisco Department of Obstetrics, Gynecology & Reproductive Sciences, San Francisco, CA.

Background: Adverse reproductive health outcomes are well-documented among people experiencing homelessness and housing instability. Little is known about abortion outcomes among this population.

Objective: To investigate the relationship between housing status and abortion outcomes, and whether gestational age mediates this relationship. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.07.002DOI Listing

Impact of the COVID-19 Pandemic on Quality of Life for Women with Ovarian Cancer.

Am J Obstet Gynecol 2020 Jun 26. Epub 2020 Jun 26.

Icahn School of Medicine at Mount Sinai, Blavatnik Family Women's Health Research Institute, New York City, New York.

Purpose: The COVID-19 pandemic has resulted in unprecedented challenges for the oncology community. For people living with cancer, treatments are interrupted, surgeries cancelled and regular oncology evaluations rescheduled. People with cancer and their physicians must balance plausible fears of COVID-19 and cancer treatment with the consequences of delaying cancer care. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318934PMC

Lumbosacral myelomeningocele before and after in utero repair.

Am J Obstet Gynecol 2020 Jun 26. Epub 2020 Jun 26.

Dept of Maternal Fetal Medicine, Mater Misericordiae Health Services Brisbane, QLD Australia.

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http://dx.doi.org/10.1016/j.ajog.2020.06.046DOI Listing

Early vaginal progesterone versus Placebo in Twin Pregnancies for prevention of spontaneous preterm birth (EVENTS): A randomised double-blind trial.

Am J Obstet Gynecol 2020 Jun 26. Epub 2020 Jun 26.

Fetal Medicine Research Institute, King's College Hospital, London, UK. Electronic address:

Background: In women with a singleton pregnancy and sonographic short cervix in mid-gestation, vaginal administration of progesterone reduces the risk of early preterm birth and improves neonatal outcomes, without any demonstrable deleterious effects on childhood neurodevelopment. In women with twin pregnancies the rate of spontaneous early preterm birth is 10-times higher than in singletons and in this respect all twins are at increased risk of preterm birth. However, six trials in unselected twin pregnancies reported that vaginal progesterone from mid-gestation had no significant effect on the incidence of early preterm birth. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.050DOI Listing

Does umbilical cord milking increase the risk of severe intraventricular hemorrhage in extreme preterm neonates? a multi treatment comparison.

Am J Obstet Gynecol 2020 Jun 25. Epub 2020 Jun 25.

Department of Obstetrics & Gynecology, University of Florida College of Medicine - Jacksonville, Florida.

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http://dx.doi.org/10.1016/j.ajog.2020.06.043DOI Listing

Pharmacologic Intervention for the Management of Retained Placenta:A Systematic Review and Meta-Analysis of Randomized Trials.

Am J Obstet Gynecol 2020 Jun 24. Epub 2020 Jun 24.

Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, Rutgers Robert Wood Johnson Medical School, NJ.

Background: Retained placenta affects 2-3.3% of all vaginal deliveries and is one of the leading causes of postpartum hemorrhage worldwide. Despite the prevalence of this condition, there is limited guidance on how to manage retained placenta. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.044DOI Listing

Delivery of monochorionic twins - lessons learned from the Twin Birth Study.

Am J Obstet Gynecol 2020 Jun 24. Epub 2020 Jun 24.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

Background: The current literature regarding the recommended mode of delivery in monochorionic-diamniotic (MCDA) twins is limited by small numbers, retrospective studies, and comparisons of outcomes of MCDA gestations to those of dichorionic-diamniotic (DCDA) gestations, instead of outcomes of trial of labor versus elective cesarean delivery for MCDA twins.

Objective: To compare perinatal and maternal outcomes of planned-cesarean delivery and planned-vaginal delivery in MCDA twin pregnancies using the Twin Birth Study data.

Study Design: A secondary analysis of the Twin Birth Study. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.048DOI Listing

Physical Exam Indicated Cerclage in Twin pregnancy: a Randomized Controlled Trial.

Am J Obstet Gynecol 2020 Jun 24. Epub 2020 Jun 24.

Maternal Fetal Medicine Division, Obstetrics and Gynecology Department, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, United States.

Background: Twin pregnancies with dilated cervix in the second trimester are at increased risk of pregnancy loss and early preterm birth; currently there is no proven therapy to prevent preterm birth in this group of women.

Objective: To determine if physical exam indicated cerclage reduces the incidence of preterm birth in asymptomatic women with twin gestations and cervical dilation diagnosed before 24 weeks of pregnancy.

Study Design: Multicenter, parallel-group, open-label, randomized controlled trial of women with twin pregnancy, and asymptomatic cervical dilation from 1-5 cm between 16 0/7 to 23 6/7 weeks were enrolled from 7/2015 to 7/2019 in 8 centers. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.047DOI Listing

Antibiotic administration reduces the rate of intraamniotic inflammation in preterm prelabor rupture of the membranes.

Am J Obstet Gynecol 2020 Jul;223(1):114.e1-114.e20

Perinatology Research Branch, Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, and Detroit, MI; Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI; Department of Obstetrics and Gynecology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, Czech Republic.

Background: Preterm prelabor rupture of the membranes (PPROM) is frequently complicated by intraamniotic inflammatory processes such as intraamniotic infection and sterile intraamniotic inflammation. Antibiotic therapy is recommended to patients with PPROM to prolong the interval between this complication and delivery (latency period), reduce the risk of clinical chorioamnionitis, and improve neonatal outcome. However, there is a lack of information regarding whether the administration of antibiotics can reduce the intensity of the intraamniotic inflammatory response or eradicate microorganisms in patients with PPROM. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.01.043DOI Listing
July 2020
4.704 Impact Factor

Radek Bukowski appointed Editor of Computational Medicine for AJOG.

Authors:
Roberto Romero

Am J Obstet Gynecol 2020 Jul;223(1):1-2

Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, and Detroit, MI. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2020.03.039DOI Listing

Contraception across the transmasculine spectrum.

Am J Obstet Gynecol 2020 Jun 23. Epub 2020 Jun 23.

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http://dx.doi.org/10.1016/j.ajog.2020.06.035DOI Listing

Research is needed to assess breakthrough bleeding rates in transmasculine individuals utilizing hormonal contraception.

Am J Obstet Gynecol 2020 Jun 23. Epub 2020 Jun 23.

Department of Surgery, Boston Children's Hospital, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2020.06.036DOI Listing

The effect of intrapartum oxygen supplementation on Category II fetal monitoring.

Am J Obstet Gynecol 2020 Jun 22. Epub 2020 Jun 22.

Department of Women's Health, University of Texas at Austin, Dell Medical School.

Objective: Maternal oxygen (O) administration for Category II electronic fetal monitoring (EFM) is a widely used intrauterine resuscitation technique, despite a paucity of evidence on its ability to improve EFM patterns. We investigated the effect of intrapartum O administration on Category II EFM patterns.

Study Design: This is a secondary analysis of a randomized trial conducted from 2016-2017, in which patients ≥ 37 weeks in active labor with Category II EFM were assigned to 10 L/min O by facemask or room air (RA) until delivery. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.037DOI Listing

Has a critical mass of women resulted in gender equity in gynecologic surgery?

Am J Obstet Gynecol 2020 Jun 22. Epub 2020 Jun 22.

Gynecologic Specialty Surgeons, Anne Arundel Medical Center, Annapolis, MD, 21401.

Gender equity in medicine and surgery has recently received widespread attention. Unlike other surgical specialties which remain majority male, Obstetrics and Gynecology has been a majority women field of medicine for nearly a decade and women have comprised the majority of trainees since the 1990s. Despite a critical mass of women, biases related to gender persist in the field. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.038DOI Listing

Fetal molding examined with transperineal ultrasound and associations with position and delivery mode.

Am J Obstet Gynecol 2020 Jun 22. Epub 2020 Jun 22.

National Center for Fetal Medicine, Trondheim University Hospital (St. Olavs hospital), Trondheim, Norway; Institute of clinical and molecular medicine, Norwegian University of Science and Technology, Trondheim, Norway. Electronic address:

Background: To accommodate passage through the birth canal, the fetal skull is compressed and reshaped, a phenomenon known as molding. The fetal skull bones are separated by membranous sutures which facilitate compression and overlap, resulting in a reduced diameter. This increases the probability of a successful vaginal delivery. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.042DOI Listing

Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: A randomized trial.

Am J Obstet Gynecol 2020 Jun 22. Epub 2020 Jun 22.

Department of Obstetrics and Gynecology, Ruhr-Universität Bochum, Bochum, Germany.

Background: Loop electrosurgical excision procedure (LEEP) may be performed under local anesthesia (LA) or general anesthesia (GA) and practice patterns differ worldwide. No randomized head-to-head comparison has been published to confirm or refute either practice.

Objective: To compare LEEP under LA versus GA regarding patient satisfaction and procedure-related outcomes such as rates of involved margins, complications, pain, and blood loss. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.041DOI Listing

Vasomotor Menopausal Symptoms and Risk of Cardiovascular Disease: A pooled analysis of six prospective studies.

Am J Obstet Gynecol 2020 Jun 22. Epub 2020 Jun 22.

School of Public Health, The University of Queensland, Brisbane, Queensland, Australia.

Background: Menopausal vasomotor symptoms (VMS, i.e., hot flushes and night sweats) have been associated with unfavorable risk factors and surrogate markers of cardiovascular disease (CVD), but their association with clinical CVD events is unclear. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.039DOI Listing

Breast cancer risk after hysterectomy with and without salpingo-oophorectomy for benign indications.

Am J Obstet Gynecol 2020 Jun 22. Epub 2020 Jun 22.

Department of Obstetrics and Gynecology, The Permanente Medical Group, Santa Clara, CA.

Background: Breast cancer risk has been extensively studied in women with genetic predisposition, i.e. BRCA1/2. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.040DOI Listing

Possible limitation to use the PAS FIGO classification.

Am J Obstet Gynecol 2020 Jun 18. Epub 2020 Jun 18.

Centre for Fetal Care and High risk Pregnancy, Department of Obstetrics and Gynecology, University of Chieti, Chieti, Italy.

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http://dx.doi.org/10.1016/j.ajog.2020.06.033DOI Listing

Persistent Breech Presentation In A Bicornuate Uterus.

Am J Obstet Gynecol 2020 Jun 18. Epub 2020 Jun 18.

Atlantic Health System, Morristown, NJ. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2020.06.030DOI Listing

Advancing Human Health in the Decade Ahead: Pregnancy as a Key Window for Discovery A Burroughs Wellcome Fund Pregnancy Think-Tank.

Am J Obstet Gynecol 2020 Jun 18. Epub 2020 Jun 18.

Office of the President, Burroughs Wellcome Fund, Research Triangle Park, NC, USA. Electronic address:

Recent revolutionary advances at the intersection of medicine, omics, data sciences, computing, epidemiology and related technologies inspire us to ponder their impact on health. Their potential impact is particularly germane to the biology of pregnancy and perinatal medicine, where limited improvement in health outcomes for women and children has remained a global challenge. We assembled a group of experts to establish a Pregnancy Think Tank to discuss a broad spectrum of major gestational disorders and adverse pregnancy outcomes that impact maternal-infant lifelong health and that should serve as targets for leveraging the many recent advances. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303037PMC

Reply.

Am J Obstet Gynecol 2020 Jun 19. Epub 2020 Jun 19.

Ultrasound Laboratory Trento, Department of Information Engineering and Computer Science, University of Trento, Trento, Italy.

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http://dx.doi.org/10.1016/j.ajog.2020.06.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303043PMC

A COST-EFFECTIVENESS ANALYSIS OF VAGINAL CO LASER THERAPY COMPARED TO STANDARD MEDICAL THERAPIES FOR GENITOURINARY SYNDROME OF MENOPAUSE-ASSOCIATED DYSPAREUNIA.

Am J Obstet Gynecol 2020 Jun 17. Epub 2020 Jun 17.

Department of Obstetrics and Gynecology, Division of Urogynecology, Stanford University Hospital, Palo Alto, CA, United States.

Background: Topical vaginal estrogen is considered the gold standard therapy for GSM-associated dyspareunia, but early investigations of energy-based devices show promise for patients with contraindications or who are refractory to vaginal estrogen cream. While evaluating safety, efficacy and long-term outcomes for novel technologies is critically important when new technologies become available to treat unmet healthcare needs, evaluation of the costs of these new technologies compared to existing therapies is also critically important, but often understudied.

Objectives: We sought to perform a cost-effectiveness analysis of three therapies for GSM including vaginal estrogen, oral ospemifene and vaginal CO laser therapy and determine if vaginal laser therapy is a cost-effective treatment for dyspareunia associated with GSM. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.032DOI Listing

Placenta accreta spectrum grading: The devil is in the histopathology details.

Am J Obstet Gynecol 2020 Jun 17. Epub 2020 Jun 17.

Department of Obstetrics and Gynecology, University of Cairo, Cairo, Egypt.

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http://dx.doi.org/10.1016/j.ajog.2020.06.025DOI Listing

Long-Acting Reversible Contraception Free-of-Charge: Two-year Discontinuation, its Risk Factors and Reasons.

Am J Obstet Gynecol 2020 Jun 17. Epub 2020 Jun 17.

Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Finland. Electronic address:

Background: Since 2013, the residents of the city of Vantaa, Finland, have been offered their first long-acting reversible contraceptive method (levonorgestrel-releasing intrauterine system, implant, and copper intrauterine device) free-of-charge.

Objectives: The primary aim was to assess the two-year cumulative discontinuation rates of long-acting reversible contraceptive methods when provided free-of-charge for first-time users in a real-world setting. Additional aims were to describe factors associated with discontinuation, and to evaluate the reasons for discontinuation. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.023DOI Listing

A call for precision in coronavirus disease case reporting: a crucial step more important now than ever.

Authors:
Wendy V Norman

Am J Obstet Gynecol 2020 Jun 17. Epub 2020 Jun 17.

Department of Family Practice, University of British Columbia, 320-5950 University Blvd, Vancouver, BC V6T1Z3, Canada; Faculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2020.06.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298475PMC

Re-Engineering Academic Departments of Obstetrics and Gynecology to Operate in a Pandemic World and Beyond - A Joint AGOS/CUCOG Statement.

Am J Obstet Gynecol 2020 Jun 16. Epub 2020 Jun 16.

Department of Obstetrics and Gynecology, University of Michigan Medical School.

The COVID-19 pandemic has significantly disrupted operations in academic Departments of Obstetrics and Gynecology throughout the U.S. and will continue to impact them for the foreseeable future. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298467PMC

A new definition of gestational hypertension? New onset blood pressures of 130-139/80-89 mmHg after 20 weeks of gestation.

Am J Obstet Gynecol 2020 Jun 15. Epub 2020 Jun 15.

Department of Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, MO.

Background: Diagnostic criteria for hypertensive disorders of pregnancy have historically been based on the American Heart Association/American College of Cardiology's definition of hypertension, previously defined as a blood pressure ≥140/90 mmHg. With the recent redefinition of hypertension, blood pressures of 130-139/80-89 mmHg are now considered abnormal.

Objective: We aimed to test whether new-onset blood pressure elevations of 130-139/80-89 mmHg after 20 weeks of gestation in previously normotensive women are associated with increased risk of adverse pregnancy outcomes, specifically development of hypertensive disorders of pregnancy. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.019DOI Listing

Exposure and seroconversion to severe acute respiratory syndrome coronavirus 2 among obstetrical healthcare providers following a contained outbreak.

Am J Obstet Gynecol 2020 Jun 15. Epub 2020 Jun 15.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, 395 West 12th Avenue, 5th Floor, Columbus, OH 43214, Columbus, OH. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2020.06.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295482PMC

Reply.

Am J Obstet Gynecol 2020 Jun 15. Epub 2020 Jun 15.

Departments of Obstetrics and Gynecology and Global Health, University of Washington, Box 356460, Seattle, WA. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2020.06.027DOI Listing

Diagnosis of coronavirus disease 2019 pneumonia in pregnant women: can we rely on lung ultrasound?

Am J Obstet Gynecol 2020 Jun 15. Epub 2020 Jun 15.

Department of Radiology, "Vincenzo Monaldi" Hospital-AORN Ospedale Dei Colli, Naples, Italy.

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http://dx.doi.org/10.1016/j.ajog.2020.06.028DOI Listing

Maternal mortality among women with coronavirus disease 2019 admitted to the intensive care unit.

Am J Obstet Gynecol 2020 Jun 15. Epub 2020 Jun 15.

Department of Obstetrics and Gynecology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY; Katz Women's Hospital, North Shore University Hospital, Northwell Health, Manhasset, NY; Katz Women's Hospital, Long Island Jewish Medical Center, Northwell Health, New Hyde Park, NY.

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http://dx.doi.org/10.1016/j.ajog.2020.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294262PMC

SMFM Special Statement: Checklists for Preeclampsia Risk-Factor Screening to Guide Recommendations for Prophylactic Low-Dose Aspirin.

Am J Obstet Gynecol 2020 Jun 15. Epub 2020 Jun 15.

In pregnant individuals with risk factors for preeclampsia, prophylactic low-dose aspirin is recommended to reduce the risk of developing preeclampsia. Fifteen distinct risk factors are recognized, including elements of current and past medical and obstetrical history, family history, and exam findings. We present checklists intended to reduce the chance that risk factors might be inadvertently overlooked and to improve the probability that aspirin is recommended for all appropriate candidates. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.003DOI Listing

COVID-19 in pregnancy was associated with maternal morbidity and preterm birth.

Am J Obstet Gynecol 2020 Jun 15. Epub 2020 Jun 15.

Department of Obstetrics and Gynecology, Strasbourg University Hospitals, Strasbourg, France.

Background: Despite the mainly reassuring outcomes for pregnant women with COVID-19 infection reported by previous case series with small sample sizes, some recent reports of severe maternal morbidity requiring intubation and of maternal deaths show the need for additional data about the impact of COVID-19 on pregnancy outcomes. This study aimed to report the maternal characteristics and clinical outcomes of pregnant women with COVID-19 disease.

Study Design: This retrospective single-center study includes all consecutive pregnant women with confirmed (laboratory-confirmed) or suspected (according to version 7. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294260PMC

Intravenous labetalol versus oral nifedipine for acute hypertension in pregnancy: effects on cerebral perfusion pressure.

Am J Obstet Gynecol 2020 Jun 13. Epub 2020 Jun 13.

Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine, Baylor College of Medicine, Houston, TX.

Background: Pregnant women with preeclampsia have been shown to have elevated cerebral perfusion pressure and impaired cerebral autoregulation compared to normal pregnant women. Transcranial Doppler is a non-invasive technique used to estimate cerebral perfusion pressure. The effects of different antihypertensives on cerebral perfusion pressure in preeclampsia is unknown. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.018DOI Listing

Gabapentin as an Adjunct to Paracervical Block for Perioperative Pain Management for First Trimester Uterine Aspiration: A Randomized Controlled Trial.

Am J Obstet Gynecol 2020 Jun 11. Epub 2020 Jun 11.

Department of Gynecology and Obstetrics, Emory University, School of Medicine, Atlanta, Georgia, USA.

Background: Pain management approaches during uterine aspiration vary, with methods including local anesthetic, oral analgesics, moderate sedation, deep sedation, or a combination of approaches. For local anesthetic approaches specifically, we continue to have suboptimal pain control [1]. Gabapentin as an adjunct to pain management has proven to be beneficial in gynecological surgery. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.011DOI Listing

Birth defects and periconception smoking.

Authors:
L Driul A P Londero

Am J Obstet Gynecol 2020 Jun 11. Epub 2020 Jun 11.

Clinic of Obstetrics and Gynecology, Hospital of Udine, University of Udine, Udine, Italy.

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http://dx.doi.org/10.1016/j.ajog.2020.06.009DOI Listing

THE MID-LIFE TRANSITION AND THE RISK OF CARDIOVASCULAR DISEASE AND CANCER II: STRATEGIES TO MAXIMIZE QUALITY OF LIFE AND LIMIT DYSFUNCTION AND DISEASE.

Am J Obstet Gynecol 2020 Jun 10. Epub 2020 Jun 10.

Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, New York.

Chronic dysfunction, disabilities and complex diseases such as cardiovascular disease, Diabetes Mellitus Type 2, osteoporosis and certain cancers among other burdens emerge and accelerate in midlife women. Previously in Part l we have described clinical and laboratory research findings which more readily explain and clarify the underlying pathogenetic mechanisms driving these clinical burdens. Included were new findings on how in particular visceral obesity and the emergence and acceleration of various components of the Metabolic Syndrome - glucotoxicity, lipotoxicity and a chronic systemic inflammatory state abetted by loss of ovarian production of estradiol and the inevitable inroads of aging generate this spectrum of clinical problems. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.008DOI Listing

Letter-to-the-Editor: Alternative Interpretation to the Findings Reported in Visualization of SARS-CoV-2 Virus Invading the Human Placenta Using Electron Microscopy.

Authors:
Douglas A Kniss

Am J Obstet Gynecol 2020 Jun 10. Epub 2020 Jun 10.

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine (Laboratory of Perinatal Research), The Ohio State University, Wexner Medical Center and College of Medicine, Columbus, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2020.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284243PMC