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    39785 results match your criteria American journal of obstetrics and gynecology[Journal]

    1 OF 796

    Preoperative Obstructive Sleep Apnea Screening in Gynecologic Oncology Patients.
    Am J Obstet Gynecol 2018 May 21. Epub 2018 May 21.
    Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, University of Wisconsin - Madison; Madison, WI. Electronic address:
    Background: Women with a gynecologic cancer tend to be older, obese, and postmenopausal, characteristics that are associated with an increased risk for obstructive sleep apnea. However, there is limited investigation regarding the condition's prevalence in this population or its impact on postoperative outcomes. In other surgical populations, patients with obstructive sleep apnea have been observed to be at increased risk for adverse postoperative events. Read More

    Is there a survival advantage in diagnosing endometrial cancer in asymptomatic postmenopausal patients? An Israeli Gynecology Oncology Group study.
    Am J Obstet Gynecol 2018 May 21. Epub 2018 May 21.
    Carmel Medical Center, Rappaport Faculty of Medicine, Technion, Haifa.
    Background: Incidental ultrasonographic findings in asymptomatic postmenopausal women, such as thickened endometrium or polyps, often lead to invasive procedures and to the occasional diagnosis of endometrial cancer. Data supporting a survival advantage of endometrial cancer diagnosed prior to the onset of postmenopausal bleeding (PMB) are lacking.

    Objective: To compare the survival of endometrial cancer patients diagnosed in asymptomatic and bleeding post-menopausal patients. Read More

    Hormonal contraception and breast cancer.
    Am J Obstet Gynecol 2018 May 17. Epub 2018 May 17.
    Memorial Sloan Kettering Cancer Center, New York, NY.
    The recent Danish cohort study reported a 20% increased risk of breast cancer among current and recent hormonal contraception users. These results are largely consistent with previous studies. This study did not report on stage of disease at diagnosis and it is not clear to what extent the apparent increased risk may be due to a small advance in the timing of diagnosis. Read More

    Cervical Ripening Balloon With and Without Oxytocin in Multiparas: A Randomized Controlled Trial.
    Am J Obstet Gynecol 2018 May 12. Epub 2018 May 12.
    Cleveland, OH, University Hospitals, Department of OB/GYN, Division of Maternal-Fetal Medicine.
    Background: The optimal method for induction of labor for multiparous women with an unfavorable cervix is unknown.

    Objective: To determine if induction of labor with simultaneous use of oxytocin and a cervical ripening balloon, compared with sequential use, increases the likelihood of delivery within 24 hours in multiparous women.

    Study Design: We performed a randomized controlled trial between November 2014 and June 2017. Read More

    Early prognostic factors of outcomes in monochorionic twin pregnancy: systematic review and meta-analysis.
    Am J Obstet Gynecol 2018 May 12. Epub 2018 May 12.
    Centre for Women's & Children Health, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, B15 2TT, UK; West Midlands Fetal Medicine Centre, Birmingham Women's and Children's NHS Foundation Trust, Mindelsohn Way, Edgbaston, B15 2TG, UK.
    Objective: Assess ability of first trimester pregnancy related factors (ultrasound measurements, maternal characteristics, biomarkers) to predict complications in monochorionic twin pregnancies DATA SOURCES: MEDLINE, EMBASE, ISI Web of Science, CINAHL, the Cochrane Central Registration of Controlled Trials and Research Registers, and Google Scholar, from inception to 12 May 2017. Grey literature and bibliographies of articles were checked.

    Study Eligibility Criteria: Studies that reported ultrasound measurements, maternal characteristics, or potential biomarkers, measured in the first trimester in monochorionic diamniotic twin pregnancies, where the potential prognostic ability between the variable and twin-twin transfusion syndrome, growth restriction, or intrauterine fetal death could be assessed. Read More

    The efficacy of antenatal steroid therapy is dependent on the duration of low-concentration fetal exposure: Evidence from a sheep model of pregnancy.
    Am J Obstet Gynecol 2018 May 9. Epub 2018 May 9.
    Division of Obstetrics and Gynaecology, The University of Western Australia, Perth, Western Australia, Australia; Cincinnati Children's Hospital Medical Centre, Cincinnati, OH, USA.
    Objective: Antenatal corticosteroids (ANS) are among the most important and widely used interventions to improve outcomes for preterm infants. ANS dosing regimens remain un-optimized and without maternal weight-adjusted dosing. We, and others, have hypothesised that once a low concentration of materno-fetal steroid exposure is achieved and maintained, the duration of the steroid exposure determines treatment efficacy. Read More

    The impact of cost sharing on women's use of annual examinations and effective contraception.
    Am J Obstet Gynecol 2018 May 9. Epub 2018 May 9.
    Institute for Healthcare Policy and Innovation, Ann Arbor, MI; University of Michigan Department of Internal Medicine, Ann Arbor, MI; Center for Value-Based Insurance Design, Ann Arbor, MI.
    Background: We sought to describe the relationship between the elimination of out-of-pocket costs and women's use of preventive care office visits and long-acting reversible contraception after accounting for baseline levels of cost sharing.

    Objectives: The objective of this analysis was to describe the relationship between the elimination of out-of-pocket costs and utilization of preventive care visits and long-acting reversible contraception insertion, while taking baseline cost sharing levels under consideration.

    Study Design: In 2017, we used administrative health plan data to examine changes in out-of-pocket costs and service utilization among 2,172,065 women enrolled in 15,118 employer-based health plans between 2008 and 2015. Read More

    Postpartum Hemorrhage Outcomes and Race.
    Am J Obstet Gynecol 2018 May 9. Epub 2018 May 9.
    Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, NY. Electronic address:
    Background: How race is associated with adverse outcomes in the setting of postpartum hemorrhage is not well characterized.

    Objective: The objective of this study was to assess how race is associated with adverse maternal outcomes in the setting of postpartum hemorrhage.

    Study Design: This retrospective cohort study utilized the National (Nationwide) Inpatient Sample (NIS) from the Agency for Healthcare Research and Quality for the years 2012 to 2014. Read More

    Reply to Letter L18-017AR1, L18-024AR1, and L18-026A_updated regarding manuscript entitled: "A validated calculator to estimate risk of cesarean after an induction of labor with an unfavorable cervix".
    Am J Obstet Gynecol 2018 May 9. Epub 2018 May 9.
    Maternal and Child Health Research Center, Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

    TEMPORARY REMOVAL: Medical abortion reversal: science and politics meet.
    Am J Obstet Gynecol 2018 May 9. Epub 2018 May 9.
    Saint Louis, MO.
    The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated. The full Elsevier Policy on Article Withdrawal can be found at: http://www. Read More

    Predicting Postoperative Day 1 Hematocrit levels after Hysterectomy.
    Am J Obstet Gynecol 2018 May 9. Epub 2018 May 9.
    Frank H. Netter MD School of Medicine, Quinnipiac University, Hamden, CT; OB GYN Department, Trinity Health of New England, Hartford, CT. Electronic address:
    Background: Swenson et al. developed a linear regression model to estimate postoperative day one (POD1) hematocrit (HCT) levels after benign hysterectomy. Predictive variables included pre-operative HCT, patient weight, estimated blood loss, intra-operative crystalloid volume, pre-operative platelet count, and hysterectomy route which predicted POD1 HCT ±5 for 100% of subjects using an internal validation set. Read More

    Characteristics Associated with Prolonged Length of Stay after Hysterectomy for Benign Gynecologic Conditions.
    Am J Obstet Gynecol 2018 May 8. Epub 2018 May 8.
    Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons; Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons; New York Presbyterian Hospital. Electronic address:
    Background: Length of stay (LOS) after surgery has become an important quality measure for many common surgical procedures and is now also tied to reimbursement. Currently, little is known about the perioperative factors that contribute to prolonged hospital LOS in women who undergo hysterectomy for benign conditions.

    Objective: We performed a population-based analysis to investigate the association between perioperative factors and prolonged LOS in women undergoing minimally invasive, abdominal, and vaginal hysterectomy. Read More

    The Comparing Options for Management: Patient-centered Results for Uterine Fibroids (COMPARE-UF) Registry: Rationale and Design.
    Am J Obstet Gynecol 2018 May 8. Epub 2018 May 8.
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC; Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC.
    Objective: To design and establish a uterine fibroid (UF) registry based in the United States (US) to provide comparative effectiveness data regarding UF treatment.

    Study Design: We report here the design and initial recruitment for the Comparing Options for Management: Patient-centered Results for Uterine Fibroids (COMPARE-UF) registry (, NCT02260752), funded by the Agency for Healthcare Research and Quality (AHRQ) in collaboration with the-Patient-Centered Outcomes Research Institute (PCORI). Read More

    Neonatal and Fetal Growth Charts to Identify Preterm Infants Less than 30 Weeks Gestation at Risk of Adverse Outcomes.
    Am J Obstet Gynecol 2018 May 8. Epub 2018 May 8.
    Vermont Oxford Network, Burlington, Vermont; Department of Pediatrics, University of Vermont College of Medicine, Burlington, Vermont.
    Background: It is unclear whether a neonatal or a fetal growth standard is a better predictor of adverse in-hospital newborn outcomes.

    Objective: We aimed to evaluate and compare the power of birth weight for gestational age to predict adverse neonatal outcomes using neonatal and fetal growth charts. Gestational age specific birth weight was examined either as a centile score or as a binary indicator for birth weight below the 10 centile (small for gestational age) using three fetal growth charts (National Institute of Child Health and Human Development, World Health Organization, and Intergrowth-21) and one neonatal sex-specific birth weight chart. Read More

    GlucoStabilizer™ software-guided insulin dosing improves intrapartum glycemic management in women with diabetes.
    Am J Obstet Gynecol 2018 May 8. Epub 2018 May 8.
    NYU Winthrop Hospital, Mineola, New York, USA. Electronic address:
    Background: During labor, maintenance of maternal euglycemia is critical to decrease the risk of neonatal hypoglycemia and associated morbidities. When continuous intravenous insulin infusion is needed, standardized insulin dosing charts have been used for titration of insulin to maintain glucose in target range. GlucoStabilizer™ is a software-guided insulin dosing system that calculates the dose of intravenous insulin needed based on metabolic parameters, target glucose concentration, and an individual's response to insulin. Read More

    The Vaginal Eukaryotic DNA Virome and Preterm Birth.
    Am J Obstet Gynecol 2018 May 5. Epub 2018 May 5.
    Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Washington University School of Medicine, St. Louis. Electronic address:
    Background: Despite decades of attempts to link infectious agents to preterm birth, an exact causative microbe or community of microbes remains elusive. Culture-independent sequencing of vaginal bacterial communities demonstrates community characteristics are associated with preterm birth, although none are specific enough to apply clinically. Viruses are important components of the vaginal microbiome and have dynamic relationships with vaginal bacterial communities. Read More

    Femur-Sparing Pattern of Abnormal Fetal Growth in Pregnant Women from New York City After Maternal Zika Virus Infection.
    Am J Obstet Gynecol 2018 May 5. Epub 2018 May 5.
    Seattle, WA; Department of Obstetrics & Gynecology, Center for Innate Immunity and Immune Disease, and Department of Global Health University of Washington; Sahlgrenska Academy, Gothenburg University, Sweden. Electronic address:
    Background: Zika virus (ZIKV) is a mosquito-transmitted flavivirus, which can induce fetal brain injury and growth restriction following maternal infection during pregnancy. Prenatal diagnosis of ZIKV-associated fetal injury in the absence of microcephaly is challenging due to an incomplete understanding of how maternal ZIKV infection affects fetal growth and the use of different sonographic reference standards around the world. We hypothesized that skeletal growth is unaffected by ZIKV infection and that the femur length can represent an internal standard to detect growth deceleration of the fetal head and/or abdomen by ultrasound. Read More

    Modulation of nuclear factor-κB signaling and reduction of neural tube defects by quercetin-3-glucoside in embryos of diabetic mice.
    Am J Obstet Gynecol 2018 May 4. Epub 2018 May 4.
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA. Electronic address:
    Background: Diabetes mellitus in early pregnancy increases the risk of birth defects in infants. Maternal hyperglycemia stimulates the expression of nitric oxide (NO) synthase 2 (NOS2), which can be regulated by transcription factors of the nuclear factor-κB (NF-κB) family. Increases in reactive nitrogen species (RNS) generate intracellular stress conditions, including nitrosative, oxidative, and endoplasmic reticulum (ER) stresses, and trigger programmed cell death (or apoptosis) in the neural folds, resulting in neural tube defects (NTDs) in the embryo. Read More

    Abdominal skeletal muscle activity precedes spontaneous menstrual cramping pain in primary dysmenorrhea.
    Am J Obstet Gynecol 2018 May 4. Epub 2018 May 4.
    Evanston IL, USA, Department of Obstetrics and Gynecology, NorthShore University HealthSystem & Pritzker School of Medicine University of Chicago. Electronic address:
    Background: Dysmenorrhea is a pervasive pain condition that affects 20-50% of reproductive-aged women. Distension of a visceral organ, such as the uterus, could elicit a viscero-motor reflex resulting in involuntary skeletal muscle activity and referred pain. Although referred abdominal pain mechanisms can contribute to visceral pain, the role of abdominal muscle activity has not yet been investigated within the context of menstrual pain. Read More

    Placenta percreta is associated with more frequent severe maternal morbidity than placenta accreta.
    Am J Obstet Gynecol 2018 May 4. Epub 2018 May 4.
    Port-Royal Maternity Unit, Department of Obstetrics Paris, Hôpitaux Universitaires Paris Centre, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Paris, France; Sorbonne Paris Cité, Université Paris Descartes, Faculté de Médecine.
    Background: Abnormally invasive placentation is the leading cause of obstetric hysterectomy and can cause poor to disastrous maternal outcomes. Most previous studies of peripartum management and maternal morbidity have included variable proportions of severe and less severe cases.

    Objective: The aim of this study was to compare maternal morbidity from placenta percreta and accreta. Read More

    Maternal pomegranate juice attenuates maternal inflammation-induced fetal brain injury by inhibition of apoptosis, neural nitric oxide synthase and NF-κB in a rat model.
    Am J Obstet Gynecol 2018 Apr 27. Epub 2018 Apr 27.
    Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel.
    Objective: Maternal inflammation is a risk factor for neonatal brain injury and future neurological deficits. Pomegranates have been shown to exhibit anti-inflammatory, anti-apoptotic and anti-oxidant activities. We hypothesized that pomegranate juice (POM) may attenuate fetal brain injury in a rat model of maternal inflammation. Read More

    Apparently conflicting meta-analyses on prophylactic negative pressure wound therapy after cesarean.
    Am J Obstet Gynecol 2018 Apr 26. Epub 2018 Apr 26.
    EPIUnit - Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas, nº135, 4050-600 Porto, Portugal; Departamento de Ciências da Saúde Pública e Forenses e Educação Médica, Faculdade de Medicina da Universidade do Porto, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal. Electronic address:

    Response to Letter to the Editor Re: Maternal and Neonatal Outcomes After Bariatric Surgery; A Systematic Review and Meta-Analysis: Do the benefits outweigh the risks?
    Am J Obstet Gynecol 2018 Apr 26. Epub 2018 Apr 26.
    Department of Medicine, University of Toronto, Toronto, ON, Canada; Division of Endocrinology and Metabolism, Mount Sinai Hospital, Toronto, ON, Canada; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. Electronic address:

    Society for Maternal-Fetal Medicine (SMFM) Consult Series #45: Mild fetal ventriculomegaly: Diagnosis, evaluation, and management.
    Am J Obstet Gynecol 2018 Apr 26. Epub 2018 Apr 26.
    Ventriculomegaly is defined as dilation of the fetal cerebral ventricles and is a relatively common finding on prenatal ultrasound. The purpose of this document is to review the diagnosis, evaluation, and management of mild fetal ventriculomegaly. When enlargement of the lateral ventricles (≥10 mm) is identified, a thorough evaluation should be performed, including detailed sonographic evaluation of fetal anatomy, amniocentesis for karyotype and chromosomal microarray analysis (CMA), and a workup for fetal infection. Read More

    Did the maternal pulse mask the fetal heart rate of acidemic infants with no explanatory features?
    Am J Obstet Gynecol 2018 Apr 26. Epub 2018 Apr 26.
    Hôpital de Thetford Mines, Department of Obstetrics and Gynecology, 1717 rue Notre Dame E Thetford Mines, QC, Canada, G6G 2V4. Electronic address:
    Maternal heart rate masking the fetal heart rate may explain the finding of acidemic infants with no explanatory features on the fetal heart rate tracing. Read More

    Cervical pessary to reduce preterm birth before 34 weeks of gestation after an episode of preterm labor and a short cervix: a randomized controlled trial.
    Am J Obstet Gynecol 2018 Apr 25. Epub 2018 Apr 25.
    Maternal-Fetal Medicine Unit. Department of Obstetrics. Hospital Universitari Vall d'Hebron. Universitat Autònoma de Barcelona. Barcelona. Spain; Maternal and Child Health and Development Network (SAMID), Instituto Salud Carlos III, Madrid, Spain.
    Background: To date, no intervention has proved effective in reducing the spontaneous preterm birth rate in singleton pregnancies following an episode of threatened preterm labor and short cervix remaining.

    Objective: This study was designed to ascertain whether cervical pessaries could be useful in preventing spontaneous preterm birth in women with singleton pregnancies and a short cervix after a threatened preterm labor episode.

    Study Design: This open randomized controlled trial was conducted in 357 pregnant women (between 24 and 33 weeks) who had not delivered 48h after a threatened preterm labor episode and had a short cervix remaining (≤25 mm at 24-29 weeks; ≤15mm at 30-33 weeks). Read More

    Identification of experimental bladder sensitivity among dysmenorrhea sufferers.
    Am J Obstet Gynecol 2018 Apr 25. Epub 2018 Apr 25.
    Department of Ob/Gyn, Northshore University HealthSystem, Evanston, IL 60201; Pritzker School of Medicine, University of Chicago, Chicago, IL 60637. Electronic address:
    Background: Dysmenorrhea is a common risk factor for chronic pain conditions including bladder pain syndrome. Few studies have formally evaluated asymptomatic bladder pain sensitivity in dysmenorrhea, and whether this largely reflects excess pelvic symptom reporting due to comorbid psychological dysfunction.

    Objective: We sought to determine whether bladder hypersensitivity is more common among women reporting moderate or greater dysmenorrhea, without chronic pain elsewhere, after accounting for anxiety and depression. Read More

    The effect of hospital acuity on severe maternal morbidity in high-risk patients.
    Am J Obstet Gynecol 2018 Apr 16. Epub 2018 Apr 16.
    Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA.
    Background: In 2015, the Society for Maternal-Fetal Medicine and the American College of Obstetricians and Gynecologists published guidelines that established levels of maternal care. These guidelines outlined the nursing, provider, and facility requirements for hospitals to be designated a birthing center or 1 of 4 levels of care. To date, these levels of maternal care have not been adopted widely; currently, no data exist on how these designations may affect maternal or neonatal outcomes. Read More

    Pregnancy and parental leave among obstetrics and gynecology residents: results of a nationwide survey of program directors.
    Am J Obstet Gynecol 2018 Apr 16. Epub 2018 Apr 16.
    Department of Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
    Background: The health and economic benefits of paid parental leave have been well-documented. In 2016, the American College of Obstetricians and Gynecologists released a policy statement about recommended parental leave for trainees; however, data on adoption of said guidelines are nonexistent, and published data on parental leave policies in obstetrics-gynecology are outdated. The objective of our study was to understand existing parental leave policies in obstetrics-gynecology training programs and to evaluate program director opinions on these policies and on parenting in residency. Read More

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