72 results match your criteria American journal of medical case reports[Journal]


Management of ST-Elevation Myocardial Infarction in the COVID-19 Era: The Role of Thrombosis and Anticoagulation Strategy.

Am J Med Case Rep 2020 22;8(9):262-267. Epub 2020 May 22.

Department of Medicine, SUNY Downstate health Sciences University, Brooklyn, NY.

Cardiac manifestations of COVID-19 include myocarditis, demand ischemia, myocardial infarction and arrhythmias with prothrombotic state being a major underlying pathogenetic mechanism. In this report we present a case of a 57-year-old, otherwise healthy, woman who presented with chest pain and nausea and was found to have an inferior wall ST-elevation myocardial infarction (STEMI) in the setting of an active COVID-19 infection. Angiography revealed tortuous coronary arteries with a 100% right coronary artery occlusion with high thrombus burden and normal left coronary system. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316192PMC

Thrombus in Transit and Impending Pulmonary Embolism Detected on POCUS in a Patient with COVID-19 Pneumonia.

Am J Med Case Rep 2020 5;8(8):225-228. Epub 2020 May 5.

Department of Internal Medicine, State University of New York, Downstate-Health Science University, Brooklyn, New York, USA, 11203.

Coronavirus disease 2019 (COVID-19) is a pandemic that started in China in December 2019 and carries a high risk of morbidity and mortality. To-date (4-22-2020) it affected over 2.6 million people and resulted in nearly 200,000 death worldwide mainly due to severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295169PMC

Right-sided Aortic Arch with Aberrant Left Subclavian Artery in a Pregnant Female: A Case Report and Literature Review.

Am J Med Case Rep 2020 ;8(6):143-147

Department of Medicine, SUNY- Downstate, Health Science University. 450 Clarkson Avenue, Brooklyn, NY 11203.

Right-sided aortic arch with aberrant left subclavian artery is a rare variant of vascular anatomy. Three types of right-sided aortic arches are described and classified based on the arrangement of the aortic arch vessels, the presence or absence of congenital heart abnormalities, the relationship of the aortic arch to the trachea and esophagus, as well as the presence or absence of a complete or incomplete vascular ring. On review of the existing literature, 31 case reports were found with a spectrum of clinical presentation sand outcomes. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295170PMC
January 2020

Primary Erythromelalgia Complicated by Cellulitis: A Case Report and Review of Literature.

Am J Med Case Rep 2020 5;8(6):153-158. Epub 2020 Apr 5.

Department of Internal Medicine, State University of New York, Downstate Health Sciences University, Brooklyn, NY 11203 USA.

Background: Erythromelalgia is a rare disease with increasing incidence. It manifests as episodic painful red extremities triggered by heat. External cooling provides temporary symptomatic relief but may lead to complications such as cellulitis. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266172PMC

Myocardial Infarction as the Initial Presentation for Fibromuscular Dysplasia.

Am J Med Case Rep 2020 12;8(7):166-172. Epub 2020 Apr 12.

Department of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, New York, United States- 11203.

Background: Fibromuscular dysplasia (FMD) is a non-atherosclerotic disease that affects medium-sized arteries and results in stenosis, dissection, aneurysm or occlusion. It is most commonly reported in the renal and carotid arteries. Involvement of coronary arteries is quite rare and and leads to serious consequences. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252985PMC

Absence of the Left Main Artery with Separate Ostia of the Left Anterior Descending Artery and Circumflex from the Left Sinus Valsalva: A Case Report.

Am J Med Case Rep 2020 19;8(5):134-136. Epub 2020 Mar 19.

Division of Cardiovascular Medicine and Department of Medicine, State University of New York Health Sciences University-Downstate Medical Center, Health + Hospitals/Kings County, Brooklyn, N.Y., U.S.A-11203.

Coronary artery anomalies are diagnosed in approximately 1% of patients who undergo coronary angiography (CAG). Several anomalies are life threatening but are generally asymptomatic and clinically insignificant. Nonetheless, proper recognition and adequate visualization is necessary for proper medical management, especially in patients undergoing percutaneous coronary intervention or cardiac surgery. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243631PMC

Neurotoxicity Associated with Radiological Contrast Agents Used during Coronary Angiography: A Systematic Review.

Am J Med Case Rep 2020 7;8(2):60-66. Epub 2020 Jan 7.

Division of Cardiovascular Disease and Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, New York, U.S.A.

Contrast media enhances the visualization of the anatomic structures in radiological studies, allowing internal tissues such as blood vessels, kidney, ureters, adrenals and other organs to be identified. The evolution of contrast media highlights the efforts to develop less toxic chemical agents that possess low viscosity and osmolality. However, adverse effects such as idiosyncratic reactions, and organ specific damage are well characterized. Read More

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http://dx.doi.org/10.12691/ajmcr-8-2-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241527PMC
January 2020

Concurrent Anaplastic and Papillary Thyroid Carcinomas: A Case Report.

Am J Med Case Rep 2020 22;8(7):202-205. Epub 2020 Apr 22.

Department of Internal Medicine, SUNY- Downstate Health Science University, Brooklyn, New York, United States- 11203.

Anaplastic thyroid cancer (ATC) is a rare, but extremely aggressive, form of cancer with a high mortality rate. Differentiated thyroid cancer (DTC), on the other hand, including papillary and follicular subtypes, are relatively common and typically follows a more indolent course. Cases have been reported in which ATC transforms from DTC, and where DTC and ATC exist simultaneously. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236945PMC

Large Left Atrial Thrombus on Amplatzer Septal Occluder Secondary to Medication Nonadherence.

Am J Med Case Rep 2020 22;8(7):197-201. Epub 2020 Apr 22.

Department of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, New York, United States-11203.

Patent foramen ovale (PFO) is a common clinical entity that is encountered in 20-34% of the general population. In most individuals, this anatomical variation is asymptomatic and goes undetected throughout their lives or is only incidentally discovered on cardiac investigations. In situations when the conduit is large enough and when the right atrial pressure exceeds the left atrial pressure, right to left interatrial flow may occur in these individuals. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236968PMC

Pharmaco-invasive Therapy for STEMI in a Patient with COVID-19: A Case Report.

Am J Med Case Rep 2020 22;8(7):192-196. Epub 2020 Apr 22.

Department of Internal Medicine, SUNY-Downstate- Health Science University, Brooklyn, New York, U.S.A.- 11203.

Coronavirus disease 2019 (COVID-19) is a pandemic that started in the Wuhan province of China in December 2019. It is associated with increased morbidity and mortality mainly due to severe acute respiratory syndrome 2 (SARS-Cov-2). Cardiac manifestations related to COVID-19 include demand ischemia, fulminant myocarditis, myocardial infarction and arrhythmias. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236913PMC

Shift From Left to a Right Bundle Block on ECG Leading to the Diagnosis of a Malpositioned Lead in the Coronary Sinus: A Case Report.

Am J Med Case Rep 2020 14;8(7):178-181. Epub 2020 Apr 14.

Division of Cardiovascular Diseases and Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, NY 11203, U.S.A.

On electrocardiography (ECG), ventricular pacing appears as a spikes that precede induced QRS complexes. The induced complexes with a right ventricular lead have the morphology of a left bundle branch block (LBBB). We describe a case of malposition right ventricular (RV) lead in the coronary sinus diagnosed based on the changes noted in the ECG tracing. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237009PMC

Snorkeling Induced Pulmonary Edema: A Case Report and Review of the Literature.

Am J Med Case Rep 2020 14;8(7):173-177. Epub 2020 Apr 14.

Division of Cardiovascular Diseases and Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, NY 11203, U.S.A.

Swimming-induced pulmonary edema (SIPE), also called immersion pulmonary edema (IPE), is a medical condition seen in various water-based activities such as scuba diving, swimming, aqua jogging, triathlete competition and snorkeling. It occurs when transcapillary filtration of low protein fluid collects in the lungs, in the absence of water aspiration during an aquatic activity, causing acute dyspnea, cough and/or hemoptysis. The hallmark of this entity is the complete resolution of symptoms within 48 hours. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236994PMC

Hemichorea-Hemiballismus as an Unusual Presentation of Hyperosmolar Hyperglycemic Syndrome.

Am J Med Case Rep 2020 5;8(6):159-161. Epub 2020 Apr 5.

Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, NY 11203 USA.

Diabetes mellitus can lead to a diverse array of systemic complications. Poorly managed hyperglycemia can result in serious neurological consequences ranging from peripheral neuropathy to seizures and coma. A rare neurologic disorder seen in acute decompensated type 2 diabetes mellitus (T2DM) is hemichorea-hemiballismus (HCHB). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236990PMC

HIV-associated Extracranial Arterial Aneurysms: A Systematic Review.

Am J Med Case Rep 2020 19;8(5):128-133. Epub 2020 Mar 19.

Internal Medicine, State University of New York- Downstate Health Science University, Brooklyn, NY, USA- 11203.

Human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) has been found to be associated with an increased risk of cardiovascular disease, and the development of arterial aneurysms in particular, intracranial aneurysms. In this review, we will review the reported HIV-associated extracranial aneurysms (HECAA) and their possible association with HIV/AIDS. We will discuss the proposed pathogenetic pathways leading to arterial aneurysms. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236995PMC

Mitral Valve Aneurysm in Mitral Valve Endocarditis:A Case Report.

Am J Med Case Rep 2020 19;8(3):83-87. Epub 2020 Jan 19.

Division of Cardiovascular Diseases and Department of Internal Medicine, State University of New York, Downstate Medical Center, Health Sciences University, Brooklyn NY 11203, USA.

Mitral valve aneurysm (MVA) is an ominous complication of infective endocarditis (IE), with worse outcomes seen among patients with preexisting valvular disease or intravenous drug use. Valve aneurysms can perforate or lead to rupture of the chordae tendineae, with the consequent development of severe mitral regurgitation and acute pulmonary edema. We present a case of a 54-year-old woman with hypertension, obesity, diabetes mellitus, hyperlipidemia, chronic obstructive pulmonary disease, peptic ulcer disease, obstructive sleep apnea, gastroesophageal reflux disease, intravenous drug abuse and bipolar disorder who developed MVA one month after being discharged for IE. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237018PMC
January 2020

Pulmonary Air embolism Associated with Pneumocephalus: A Case Report.

Am J Med Case Rep 2020 14;8(5):119-122. Epub 2020 Mar 14.

Department of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, New York, United States- 11203.

Iatrogenic air embolism is associated with significant morbidity and mortality. Retrograde cerebral venous air embolism is most frequently associated with manipulation of venous access most commonly from central venous catheters. The ascension of air to the cerebral circulation is possibly due to the low specific gravity of air compared to blood and the performance of procedures in the sitting position. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194233PMC

A Case of Thrombus in Transit: Role of POCUS in Early Diagnosis of Pulmonary Thromboembolism.

Am J Med Case Rep 2020 7;8(2):67-69. Epub 2020 Jan 7.

Division of Cardiovascular Diseases and Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn NY 11203, USA.

Pulmonary embolism is a cause of significant morbidity and mortality. Thrombus in transit is defined on ultrasound as mobile echogenic material, temporarily located in the right heart chambers making its way to the pulmonary vasculature, which is highly diagnostic of pulmonary embolism. Point-of-care ultrasound (POCUS) places significant role in early diagnosis of thrombus in transit. Read More

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http://dx.doi.org/10.12691/ajmcr-8-2-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062378PMC
January 2020

Vagal-induced Complete Heart Block during Coronary Angiography due to Bladder Distention.

Am J Med Case Rep 2020 6;8(2):56-59. Epub 2020 Jan 6.

Division of Cardiovascular Diseases, Department of Medicine, State University of New York Health Sciences University, Downstate Medical Center, Brooklyn, NY 11203, U.S.A.

Vagal stimulation is common during angiographic procedures. A vasovagal reaction in the setting of coronary angiography most commonly presents as hypotension and/or bradycardia. While the array of signs and symptoms of vasovagal reactions are known, atrioventricular (AV) block maybe overlooked due to its intermittent nature. Read More

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http://dx.doi.org/10.12691/ajmcr-8-2-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062381PMC
January 2020

Angio-Seal Vascular Closure Related Acute Limb Ischemia: A Case Report.

Am J Med Case Rep 2020 25;8(2):49-52. Epub 2019 Dec 25.

Division of Cardiovascular Diseases and Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, NY 11203, U.S.A.

Vascular Closure Devices (VCD) are routinely used in cardiac catheterization and other endovascular procedures in order to achieve immediate post-procedural hemostasis and sealing of the femoral artery puncture site. Unlike manual compression, VCD encompass a broad range of devices, with varying mechanisms, that offer the advantage of achieving rapid hemostasis, increased patient comfort and mobility, decreased reliance on hospital staff resources, and facilitate earlier hospital discharge. Complications of VCD have been well-described and include embolization, arterial occlusion, infection, or vascular obstruction. Read More

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http://dx.doi.org/10.12691/ajmcr-8-2-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062382PMC
December 2019

Tacrolimus-induced Diabetic Ketoacidosis in a Polymyositis Patient Precipitated by Fluconazole: A Case Report and Review of the Literature.

Am J Med Case Rep 2020 18;8(3):76-78. Epub 2020 Jan 18.

Department of Medicine, SUNY-Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, New York 11203, USA.

Tacrolimus is a reversible calcineurin inhibitor. It is commonly used as an immunosuppressive drug in the treatment of T cell mediated diseases such as polymyositis, graft rejection in solid organ transplant, graft-versus-host disease in hematopoietic stem cell transplant, and is postulated to have diabetogenic potential. Fluconazole, on the other hand, is frequently prescribed antifungal therapy. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059733PMC
January 2020

Myocardial Infarction Secondary to Marijuana-Induced Coronary Vasospasm.

Am J Med Case Rep 2020 18;8(3):76-78. Epub 2020 Jan 18.

Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, NY, USA - 11203.

With the rise of the number of states fully legalizing marijuana, the use of this substance in the United States is at an all-time high. This increasing legalization gives the impression that marijuana is rather safe. However, multiple reports by our groups and others documented serious cardiovascular complications associated with marijuana use ranging from life threatening arrhythmia to myocarditis and myocardial infarction. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059731PMC
January 2020

Simultaneous Cardiotoxicity and Neurotoxicity Associated with 5-fluorouracil Containing Chemotherapy: A Case Report and Literature Review.

Am J Med Case Rep 2020 17;8(3):73-75. Epub 2020 Jan 17.

Department of Medicine, SUNY-Downstate Health Science University, 450 Clarkson Avenue, Brooklyn, New York 11203, USA.

We present a case of simultaneous cardiotoxicity and stroke-like neurotoxicity in a patient treated with FOLFOX, a 5-Fluorouracil (5-FU)-containing chemotherapy regimen. Within hours of FOLFOX infusion, the patient began to exhibit signs and symptoms of myocardial ischemia and stroke mimic. Coronary vasoconstriction and vasospasm is a known mechanism of 5-FU-induced cardiotoxicity. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059734PMC
January 2020

Helmet Sign on EKG: A Rare Indicator of Poor Prognosis in Critically Ill Patients.

Am J Med Case Rep 2019 6;7(10):260-263. Epub 2019 Aug 6.

Department of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, New York, United States-11203.

Background: The 'Spiked Helmet' is an electrocardiogram (EKG) finding occasionally seen in critically ill patients characterized by ST segment elevation usually represented as a 'spike and dome' pattern with elevation in the EKG baseline prior to the R wave and adjoining ST segment elevation resembling the German military helmet of the Prussian Empire. In the few cases reported in literature, this finding has been associated with very poor clinical outcomes, including in-hospital death. Although ST elevation is not uncommon in critically ill patients, these findings of a 'Spiked Helmet' sign are often transient and typically not associated with acute coronary syndrome. Read More

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http://dx.doi.org/10.12691/ajmcr-7-10-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953376PMC

Acute Heart Failure in Scleroderma Renal Crisis: A Case Study for Review of Cardiac Disease in Systemic Sclerosis.

Am J Med Case Rep 2020 5;8(1):1-7. Epub 2019 Nov 5.

Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, N.Y., U.S.A-11203.

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http://dx.doi.org/10.12691/ajmcr-8-1-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878899PMC
November 2019

Interstitial Lung Disease as the Initial Manifestation of Rheumatoid Arthritis: A Case Report and Review of the Literature.

Am J Med Case Rep 2019 28;7(12):342-347. Epub 2019 Oct 28.

Department of Internal Medicine, Downstate Medical Center, State University of New York, Brooklyn, New York, United States 11203.

Background: Rheumatoid arthritis (RA) is a chronic, systemic, inflammatory disorder that primarily affects synovial joints. Approximately 18-41% of patients with RA develop extra-articular manifestations [1]. However, extra-articular manifestations preceding or occurring without articular symptoms in RA have rarely been reported. Read More

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http://dx.doi.org/10.12691/ajmcr-7-12-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863351PMC
October 2019

Ticagrelor and Statin Interaction Induces Rhabdomyolysis and Acute Renal Failure: Case reports and Scoping Review.

Am J Med Case Rep 2019 18;7(12):337-341. Epub 2019 Oct 18.

Division of Cardiovascular Disease and Department of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, New York, United States-11203.

Ever since evidence about the increased risk of stent thrombosis with drug eluting stents (DES) surfaced in 2005, the Food and Drug Administration (FDA) has recommended the use of dual antiplatelet therapy (aspirin with P2Y12 inhibitor) following DES placement. The PLATO trial demonstrated lower mortality rates with the use of Ticagrelor when compared to clopidogrel (9.8% vs. Read More

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http://dx.doi.org/10.12691/ajmcr-7-12-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863346PMC
October 2019

Acute Psychosis Precipitated by Urinary Tract Infection in a Patient with Gliosis of the Basal Ganglia.

Am J Med Case Rep 2019 Dec;7(12):329-333

Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, NY 11203 USA.

Background: Urinary tract infections (UTI) have been found to be associated with a variety of neuropsychiatric disorders, and could play a role in the pathophysiology of relapse of affective and nonaffective psychosis. In addition, prior history of infarction in areas of the brain such as the cerebellum, basal ganglia, and mid-brain have been reported in patients with new onset psychotic symptoms.

Case Presentation: A 29-year-old woman was brought to the hospital with acute mental status changes and signs of sepsis. Read More

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http://dx.doi.org/10.12691/ajmcr-7-12-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834351PMC
December 2019
1 Read

Duodenal Varix Rupture - A Rare Cause of Fatal Gastrointestinal Hemorrhage: A Case Report and Review of Literature.

Am J Med Case Rep 2019 24;7(4):62-66. Epub 2019 Apr 24.

Department of Internal Medicine, SUNY Downstate Medical Center, Brooklyn, NY, USA.

Duodenal varices are a rare complication of portal hypertension; with cirrhosis being the most common cause. Reports regarding the disease prognosis and natural history are limited. In addition to the diagnostic difficulty, ectopic duodenal varices pose a significant therapeutic challenge owing to the lack of specific management guidelines. Read More

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http://dx.doi.org/10.12691/ajmcr-7-4-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812512PMC
April 2019
1 Read

STEMI and CVA in Hypercoagulable State with Ostium Secundum Defect.

Am J Med Case Rep 2019 22;7(12):320-324. Epub 2019 Sep 22.

SUNY-Downstate, Brooklyn, New York USA.

Atrial septal defect (ASD) is a risk factor for multiple vascular thrombotic events, which can occur either sequentially or simultaneously. In this report we present a case of ST-elevation myocardial infarction (STEMI) and cerebrovascular accident (CVA). The severity of adverse cardiovascular or cerebrovascular events can be increased by the presence of specific type of ASD, such as a patent foramen ovale (PFO) or osteum secundum defect. Read More

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http://dx.doi.org/10.12691/ajmcr-7-12-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812527PMC
September 2019

Malignant Course of the Right Coronary Artery Originating from the Left Main Coronary Artery: An Odd Exit.

Am J Med Case Rep 2019 Dec;7(12):311-316

Department of Medicine, State University of New York, Downstate Medical Center, United States.

Introduction: Congenital coronary artery anomalies are quite uncommon with estimates ranging from 0.2% to 1.3% on coronary angiography. Read More

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http://dx.doi.org/10.12691/ajmcr-7-12-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800227PMC
December 2019
2 Reads

Wellens' Syndrome in a HIV-positive Patient: A Case Report.

Am J Med Case Rep 2019 6;7(11):297-300. Epub 2019 Sep 6.

Division of Cardiovascular Disease and Department of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, New York, United States-11203.

Patients with human immunodeficiency virus (HIV) are at higher risk for coronary artery disease, due to accelerated atherosclerosis resulting from chronic inflammation, the prevalence of cardiovascular risk factors and the side effects of highly active antiretroviral therapy (HAART). The Wellens' pattern is an electrocardiographic (ECG) finding that represents critical proximal left anterior descending (LAD) coronary artery stenosis that, that when is not promptly treated, can lead to extensive anterior wall myocardial infarction and death. Very few cases of Wellens' syndrome in HIV positive patients have been reported. Read More

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http://dx.doi.org/10.12691/ajmcr-7-11-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759329PMC
September 2019
3 Reads

Intrahepatic Cholestasis in a Sickle Cell Patient Unresponsive to Exchange Blood Transfusion.

Am J Med Case Rep 2019 25;7(4):67-70. Epub 2019 Apr 25.

Department of Gastroenterology and Hepatology, SUNY Downstate Medical Center, Brooklyn, NY, USA.

With the advent of hydroxyurea, the sickle cell population has been enjoying a prolonged life span as compared to the pre-hydroxyurea era. Traditionally, acute complications of sickle cell disease includes acute chest syndrome, MI and stroke. In this report we present a case of an elderly man with sickle cell disease who presented with intrahepatic cholestasis (SCIC); a rather rare and fatal complication of sickle cell hemoglobinopathy. Read More

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http://dx.doi.org/10.12691/ajmcr-7-4-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750246PMC
April 2019
1 Read

CD4 Levels and Viral Load during Ulcerative Colitis Flares in Patients with Human Immunodeficiency Virus: A Case Series.

Am J Med Case Rep 2019 10;7(8):162-166. Epub 2019 Jul 10.

Department of Medicine, SUNY Downstate Health Sciences University, Brooklyn, New York.

Background: The "Remission Hypothesis" suggests that in patients with both HIV and UC an immunosuppressed state allows for the remission of UC and decreased number of flares. While the exact mechanism is unknown, this theory considers the relationship between CD4 count and flare progression. However, currently literature does not take into account the role that viral load might play in modulating flare activity. Read More

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http://dx.doi.org/10.12691/ajmcr-7-8-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738950PMC
July 2019
2 Reads

Congenital Absence of Left Main Coronary Artery with Anomalous Origin of Left Anterior Descending and Left Circumflex Arteries Presenting with Acute Non-ST Elevation Myocardial Infarction.

Am J Med Case Rep 2019 12;7(10):264-266. Epub 2019 Aug 12.

Department of Internal Medicine, Division of Cardiology, State University of New York: Downstate Medical Center, Brooklyn, New York, United States-11203.

Congenital coronary artery anomalies are rare disease entities, occur only in 0.3%-5.6% of the general population. Read More

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http://dx.doi.org/10.12691/ajmcr-7-10-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739075PMC
August 2019
2 Reads

Defining Features of Patients who Develop Takotsubo Cardiomyopathy during Myasthenic Crisis: A Systematic Review of Case Studies.

Am J Med Case Rep 2019 19;7(9):203-209. Epub 2019 Jul 19.

Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, NY 11203, U.S.A.

Background: Myasthenic crisis can induce Takotsubo cardiomyopathy leading to transient systolic and diastolic left ventricular dysfunction and wall-motion abnormalities, including the characteristic apical ballooning. We aimed to define the clinical features of this disease entity.

Methods: A systematic review was conducted to examine the characteristics of Takotsubo cardiomyopathy presenting in myasthenia gravis patients. Read More

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http://pubs.sciepub.com/ajmcr/7/9/6/index.html
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http://dx.doi.org/10.12691/ajmcr-7-9-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728802PMC
July 2019
3 Reads

Ventricular Tachycardia Ablation Complicated with Ventricular Rupture.

Am J Med Case Rep 2019 11;7(8):176-179. Epub 2019 Jul 11.

Department of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, New York, United States-11203.

Patients with cardiomyopathy (CM) are at increased risk for sudden cardiac death (SCD), specifically, secondary to ventricular arrhythmias such as ventricular tachycardia (VT) or ventricular fibrillation (VF). Those that have CM are further stratified based on risk of death from ventricular arrhythmias. If determined high risk, implantable cardioverter-defibrillators (ICD), anti-arrhythmic medication or even ablation procedures are considered in order to minimize the risk of SCD. Read More

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http://dx.doi.org/10.12691/ajmcr-7-8-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727849PMC
July 2019
2 Reads

Leukocytosis Associated with Esophageal Squamous Cell Carcinoma as a Predictor of Poor Prognosis - A Case Report and Review of Literature.

Am J Med Case Rep 2019 22;7(1):9-12. Epub 2019 Jan 22.

Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, N.Y, U.S.A- 11203.

Leukocytosis, specifically granulocytosis in malignancy is a common finding with various etiologies. Graulocytosis associated with esophageal cancer has not commonly been reported in case reports in the United States. Furthermore, granulocyte colony stimulating factor (G-CSF) producing tumors have been associated with a variety of cancers. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724536PMC
January 2019
6 Reads

A Case Report of Intraoperative Coagulopathy Secondary to Chronic Vitamin K Deficiency.

Am J Med Case Rep 2019 11;7(8):167-169. Epub 2019 Jul 11.

Department of Internal Medicine, Kings County Medical Center, Brooklyn, NY, 11203, USA.

Dietary Vitamin K is a well-known anti-hemorrhagic agent that plays an integral role in the coagulation pathway. Vitamin K is involved in synthesis of coagulation factors; II, VII, IX and factor X. Vitamin K deficiency leads to bleeding diathesis. Read More

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http://dx.doi.org/10.12691/ajmcr-7-8-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711617PMC
July 2019
2 Reads

Aorta-Right Atrial Tunnel Causing Heart Failure in a Young Female.

Am J Med Case Rep 2019 12;7(11):267-270. Epub 2019 Aug 12.

Department of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, New York, United States.

Aorta-right atrial tunnel is a rare entity characterized by a vascular fistula, which connects one of the sinuses of Valsalva in the ascending aorta and the right atrium. It is frequently associated with congestive heart failure. This abnormality is usually diagnosed by echocardiography or CT angiography. Read More

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http://dx.doi.org/10.12691/ajmcr-7-11-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711612PMC

Late Presentation of Carfilzomib Associated Thrombotic Microangiopathy.

Am J Med Case Rep 2019 31;7(10):240-243. Epub 2019 Jul 31.

Department of internal Medicine, State University of New York-Downstate, Brooklyn, New York, USA.

Multiple Myeloma (MM) is a plasma cell disorder characterized by abnormal proliferation of plasma cells resulting in overproduction of paraprotein. Proteasome inhibitors (PI) have been a corner stone for the treatment of MM. Thrombotic Microangiopathy (TMA) is a recent hematological adverse event that has newly been recognized in multiple PI. Read More

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http://pubs.sciepub.com/ajmcr/7/10/5/index.html
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http://dx.doi.org/10.12691/ajmcr-7-10-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711615PMC
July 2019
4 Reads

Rare Case of Bilateral Cerebellar Hemorrhage in a Male Boxer.

Am J Med Case Rep 2019 31;7(10):236-239. Epub 2019 Jul 31.

Department of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, New York, United States-11203.

The sport of boxing carries with it the risk of brain injury with acute and chronic neurological injuries such has contusion, concussion and intracranial bleeding has been reported. The force sustained from a boxing blow can be as powerful as being hit with a 6-kg wooden mallet striking at 20 mph. Bilateral cerebellar hemorrhage secondary to trauma is a rare entity that has not been reported in the literature previously. Read More

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http://dx.doi.org/10.12691/ajmcr-7-10-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711611PMC
July 2019
3 Reads

Amyotrophic Lateral Sclerosis, a Possible Sequela of Chronic Myeloid Leukemia.

Am J Med Case Rep 2019 31;7(10):230-235. Epub 2019 Jul 31.

Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, N.Y, U.S.A-11203.

Amyotrophic lateral sclerosis is a fatal neurodegenerative disorder with progressive deterioration of both upper and lower motor neuron functions. It is a rare disease with one study demonstrating a prevalence of 3.9 cases per 100,000 in the USA in the year 2010-2011. Read More

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http://dx.doi.org/10.12691/ajmcr-7-10-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707770PMC
July 2019
1 Read

Refractory Metastatic Insulinoma Treated with Everolimus, Complicated by Cryptogenic Organizing Pneumonia.

Am J Med Case Rep 2019 18;7(7):125-132. Epub 2019 Jun 18.

Department of Medicine and Department of Endocrinology, State University of New York: Downstate Medical Center.

Insulinoma is a rare neuroendocrine pancreatic islet cell tumor of which the majority are benign and solitary. Its estimated incidence is 2 to 4 cases per 1 million person-years. We report the case of an 82-year-old female who presented with metastatic insulinoma to the liver and retroperitoneal lymph nodes. Read More

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http://dx.doi.org/10.12691/ajmcr-7-7-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693857PMC
June 2019
3 Reads

Longitudinally Extensive Transverse Myelitis Associated With Systemic Lupus Erythematosus: A Case Report and Literature Review.

Am J Med Case Rep 2019 31;7(10):244-249. Epub 2019 Jul 31.

Department of Medicine, State University of New York, Downstate Medical Center, Brooklyn, NY 11203 USA.

Background: Lupus myelitis is a rare but disastrous complication of systemic lupus erythematosus (SLE). The transverse myelitis (TM) may involve three or more contiguous spinal cord segments and as such is designated longitudinally extensive transverse myelitis (LETM). The neurological presentation may vary based on the location of the pathology and may consist of a combination of sensory and motor deficits. Read More

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http://dx.doi.org/10.12691/ajmcr-7-10-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691358PMC
July 2019
1 Read

Recurrent Anion Gap Metabolic Acidosis.

Am J Med Case Rep 2019 19;7(9):200-202. Epub 2019 Jul 19.

State University of New York, Downstate Medical Center, Department of Internal Medicine, Brooklyn, NY 11203 USA.

Background: Metabolic acidosis refers to any process that increases the hydrogen ions in the body and reduces the bicarbonate concentration. Metabolic acidosis is subdivided based on presence of anion gap (AG), and AG metabolic acidosis is most often due to ketoacidosis, lactic acidosis, renal failure, or toxic ingestions. AG metabolic acidosis is frequently encountered in the clinical practice. Read More

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http://pubs.sciepub.com/ajmcr/7/9/5/index.html
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http://dx.doi.org/10.12691/ajmcr-7-9-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690845PMC
July 2019
4 Reads

Thyrotoxic Periodic Paralysis with Sensory Deficits in Young African American Male: A Case Report and Literature Review.

Am J Med Case Rep 2019 26;7(7):138-142. Epub 2019 Jun 26.

Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, N.Y, U.S.A-11203.

Thyrotoxic periodic paralysis is a sporadic entity characterized by hypokalemia and paralysis in the setting of hyperthyroidism. TPP is most commonly described in young Asian males. Studies have shown an association with mutations affecting inward rectifying potassium channels. Read More

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http://dx.doi.org/10.12691/ajmcr-7-7-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688769PMC
June 2019
2 Reads

Atrioventricular Nodal Reentrant Tachycardia Triggered by Marijuana Use: A Case Report and Review of the Literature.

Am J Med Case Rep 2019 16;7(9):193-196. Epub 2019 Jul 16.

Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, N.Y, U.S.A-11203.

Marijuana is the most commonly abused recreational substance. With the increasing legalization of marijuana, its use is expected to rise. Delta-9-tetrahydrocannabinol (THC) is the psychotropic component of marijuana, acting via CB1 and CB2 G-protein coupled cannabinoid receptors. Read More

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http://dx.doi.org/10.12691/ajmcr-7-9-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687317PMC
July 2019
5 Reads

Argatroban-refractory, Heparin-induced Thrombocytopenia after Coronary Intervention with Radial Artery Occlusion.

Am J Med Case Rep 2019 14;7(9):184-190. Epub 2019 Jul 14.

Department of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, New York, United States-11203.

Heparin induced thrombocytopenia (HIT) is serious disorder that occurs in a small percentage of patients following exposure to heparin. HIT can further be classified into two types: HIT type 1 and type 2. Type 2 HIT is a potentially life threatening with clinically significant outcomes. Read More

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http://dx.doi.org/10.12691/ajmcr-7-9-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687314PMC
July 2019
2 Reads

Bladder Distension: An Overlooked Cause Vagal-induced Hypotension during Coronary Angiography.

Am J Med Case Rep 2019 14;7(8):180-183. Epub 2019 Jul 14.

Department of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, New York, United States-11203.

Hypotension is a common complication during coronary angiography. Multiple factors can lead to hypotension in cath lab including bleeding and vasovagal reaction. Vagal induced hypotension is commonly associated with severe pain and anxiety. Read More

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http://dx.doi.org/10.12691/ajmcr-7-8-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687318PMC

An Unexpected Pregnancy Test Result Leading to the Diagnosis of Advanced Gastric Cancer.

Am J Med Case Rep 2019 5;7(7):148-150. Epub 2019 Jul 5.

Division of Medicine, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA.

The presence of beta human chorionic gonadotropin in the absence of pregnancy warrants further workup as elevated levels may be seen in trophoblastic disease or germ cell tumors and rarely in solid tumors such as gastric cancers. The signs and symptoms of gastric cancer are vague and as such, the diagnosis is often delayed. Overexpression of the beta-subunit of human chorionic gonadotrophin may be seen in close to 50% of gastric cancers. Read More

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http://dx.doi.org/10.12691/ajmcr-7-7-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687315PMC
July 2019
2 Reads