7,208 results match your criteria American journal of hypertension[Journal]


Too Much Sugar is Not Good for the Fetus.

Authors:
Bonita Falkner

Am J Hypertens 2019 Feb 16. Epub 2019 Feb 16.

Thomas Jefferson University Philadelphia, PA.

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http://dx.doi.org/10.1093/ajh/hpz025DOI Listing
February 2019
1 Read

Maternal blood pressure, cord glucocorticoids, and child neurodevelopment at 2 years of age: a birth cohort study.

Am J Hypertens 2019 Feb 16. Epub 2019 Feb 16.

Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Background: Pregnancy hypertensive disorders have impaired neurodevelopment in offspring. We aimed to explore the association of normal range maternal blood pressure (BP) with child neurodevelopment, as well as the possible role of placental 11-beta-hydroxysteroid dehydrogenase type 2 (11β-HSD2) therein.

Methods: Among 1,008 mother-child pairs recruited in Wuhan, China, in 2013-2015, we measured maternal third-trimester BP (systolic and diastolic BP, SBP and DBP) and cord glucocorticoids (cortisol and cortisone), a marker reflecting placental 11β-HSD2 activity. Read More

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http://dx.doi.org/10.1093/ajh/hpz024DOI Listing
February 2019

Nondipping Pattern and Cardiovascular and Renal Damage in a Population-Based Study (The Stanislas Cohort Study).

Am J Hypertens 2019 Feb 7. Epub 2019 Feb 7.

FCRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), Nancy, France.

Objective: The attenuation of physiological nocturnal decline of blood pressure (BP) - called nondipper pattern - has previously been reported to be associated with target organ damage in hypertensive subjects. However, this association remains debated and poorly studied in normotensive patients. The present study aimed to investigate the association between nondipper pattern and subclinical cardiovascular and renal damage in an initially healthy population-based cohort study. Read More

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http://dx.doi.org/10.1093/ajh/hpz020DOI Listing
February 2019
5 Reads

The Aldosterone/Renin Ratio predicts cardiometabolic disorders in subjects without classic primary aldosteronism.

Am J Hypertens 2019 Feb 9. Epub 2019 Feb 9.

Department of Endocrinology, School of Medicine, Pontificia Universidad Católica de Chile. Avda Libertador Bernardo O´Higgins, Santiago Centro, Santiago, Chile.

Background: Aldosterone has been linked with obesity, metabolic syndrome (MetS), pro-inflammatory and pro-thrombotic states; however, most studies relate these indicators with primary aldosteronism (PA), excluding non-PA patients.

Objective: To determine whether aldosterone, renin or the plasma aldosterone/renin ratio (ARR) are associated with metabolic disorders and inflammatory/vascular biomarkers in a non-PA population.

Methods: We studied 275 patients including adolescents and adults of both genders and measured plasma and urinary aldosterone and determined the plasma renin activity (PRA). Read More

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http://dx.doi.org/10.1093/ajh/hpz023DOI Listing
February 2019
1 Read

Plasma Renin Activity Is a Predictive Biomarker of Blood Pressure Response in European but not in African Americans With Uncomplicated Hypertension.

Am J Hypertens 2019 Feb 9. Epub 2019 Feb 9.

Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, FL.

Background: Inter-individual variability in blood pressure (BP) response to antihypertensives has been reported. Although plasma renin activity (PRA) is a potential biomarker for personalizing antihypertensive therapy in European-American (EA) and African-American (AA) hypertensives, clinical utility of PRA-guided prescribing is incompletely understood.

Methods: sing systematic-phased-approach, PRA's clinical utility was assessed. Read More

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http://dx.doi.org/10.1093/ajh/hpz022DOI Listing
February 2019
2 Reads

1-adrenoceptor polymorphisms and blood pressure: 49S variant increases plasma renin but not blood pressure in hypertensive patients.

Am J Hypertens 2019 Feb 11. Epub 2019 Feb 11.

Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge, United Kingdom.

Background: Activation of beta-1 adrenoreceptors (β1-AR) in the kidney releases renin that plays a major role in the maintenance of blood pressure. Genetic variation in the β1-AR could therefore alter the physiological and clinical effects of this hormone. We tested this hypothesis in patients from a primary care cohort being screened for primary hyperaldosteronism, PHA (n=465). Read More

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http://dx.doi.org/10.1093/ajh/hpz019DOI Listing
February 2019
1 Read

Health behaviors, nocturnal hypertension and non-dipping blood pressure: The Coronary Artery Risk Development in Young Adults and Jackson Heart Study.

Am J Hypertens 2019 Feb 2. Epub 2019 Feb 2.

University of Alabama at Birmingham, Birmingham, Alabama, USA.

Background: Several health behaviors have been associated with hypertension based on clinic blood pressure (BP). Data on the association of health behaviors with nocturnal hypertension and non-dipping systolic BP (SBP) are limited.

Methods: We analyzed data for participants with ambulatory BP monitoring (ABPM) at the Year 30 Coronary Artery Risk Development in Young Adults (CARDIA) study exam in 2015-2016 (n=781) and the baseline Jackson Heart Study (JHS) exam in 2000-2004 (n=1,046). Read More

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http://dx.doi.org/10.1093/ajh/hpz017DOI Listing
February 2019
9 Reads
2.852 Impact Factor

Dysregulation of HDAC9 represses trophoblast cell migration and invasion through TIMP3 activation in preeclampsia.

Am J Hypertens 2019 Feb 2. Epub 2019 Feb 2.

Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.

Background And Objective: Preeclampsia (PE) is a common disease during pregnancy. It is generally accepted that PE is closely associated with shallow placenta implantation caused by the dysfunction of trophoblast cells. Trophoblasts have been recognized to share histological and behavioral characteristics with cancer cells, and many lines of evidence have emphasized that histone deacetylases (HDACs) are therapeutic targets for cancer treatment with the most promising. Read More

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http://dx.doi.org/10.1093/ajh/hpz006DOI Listing
February 2019
1 Read
2.852 Impact Factor

Molecular and Cellular Effect of Angiotensin 1-7 on Hypertensive Kidney Disease.

Am J Hypertens 2019 Jan 29. Epub 2019 Jan 29.

Division of Cardiovascular Diseases Department of Medicine University of Tennessee Health Science Center Memphis, Tennessee.

Background: Studies implicate that Ang1-7 imparts protective effects in the kidney. However, its relevance in hypertensive kidney disease is not fully understood. The purpose of this study is to explore the role of Ang1-7 on renal damage/remodeling during hypertension and its potential underlying molecular-cellular mechanisms. Read More

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https://academic.oup.com/ajh/advance-article/doi/10.1093/ajh
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http://dx.doi.org/10.1093/ajh/hpz009DOI Listing
January 2019
1 Read

Tissue transglutaminase-mediated AT1 receptor sensitization underlies pro-inflammatory cytokine LIGHT-induced hypertension.

Am J Hypertens 2019 Feb 2. Epub 2019 Feb 2.

Department of Biochemistry and Molecular Biology, University of Texas McGovern Medical School at Houston.

Background: Although numerous recent studies have shown a strong link between inflammation and hypertension, the underlying mechanisms by which inflammatory cytokines induce hypertension remain to be fully elucidated. Hypertensive disorders are also associated with elevated pressor sensitivity. Tissue transglutaminase (TG2), a potent crosslinking enzyme, is known to be transcriptionally activated by inflammatory cytokines and stabilize angiotensin II (Ang II) receptor AT1 (AT1R) via ubiquitination-preventing posttranslational modification. Read More

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http://dx.doi.org/10.1093/ajh/hpz018DOI Listing
February 2019
1 Read
2.852 Impact Factor

Association of Orthostatic Hypotension Timing with Clinical Events in Adults with Diabetes and Hypertension: Results from the ACCORD Trial.

Am J Hypertens 2019 Jan 31. Epub 2019 Jan 31.

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

Objective: To determine the effects of orthostatic hypotension (OH) measurement timing on its associations with dizziness, falls, fractures, CVD, and mortality.

Methods: We analyzed OH measurements from the ACCORD BP trial, which evaluated two BP goals (systolic BP [SBP]<120mmHg versus SBP<140mmHg) and incident cardiovascular disease (CVD) among adults with diabetes and hypertension. Seated BP was measured after 5 minutes of rest at baseline and follow-up visits (12-month, 48-month, and exit). Read More

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http://dx.doi.org/10.1093/ajh/hpz015DOI Listing
January 2019

Dapagliflozin Attenuates Cardiac Remodeling in Mice Model of Cardiac Pressure Overload.

Am J Hypertens 2019 Jan 25. Epub 2019 Jan 25.

Department of Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Background: Dapagliflozin (DAPA) is an inhibitor of sodium-glucose cotransporter 2 (SGLT2) prescribed for type 2 diabetes mellitus (T2DM). DAPA plays a protective role against cardiovascular diseases. Nevertheless, the effect and mechanism of DAPA on pressure overload-induced cardiac remodeling has not been determined. Read More

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https://academic.oup.com/ajh/advance-article/doi/10.1093/ajh
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http://dx.doi.org/10.1093/ajh/hpz016DOI Listing
January 2019
5 Reads

Amplified Association Between Blood Pressure and Albuminuria in Overweight Patients with Biopsy-Proven Hypertensive Nephrosclerosis.

Am J Hypertens 2019 Jan 26. Epub 2019 Jan 26.

Department of Nephrology and Laboratory Medicine, Kanazawa University, Takara-machi, Kanazawa, Ishikawa, Japan.

Background: An overweight person is at high risk for hypertensive renal damage. The effect of weight on the association between systolic blood pressure (SBP) and albuminuria remains unknown in patients with histologically diagnosed hypertensive nephrosclerosis.

Methods: A total of 97 patients with biopsy-confirmed hypertensive nephrosclerosis were recruited from 13 centers throughout Japan. Read More

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http://dx.doi.org/10.1093/ajh/hpz010DOI Listing
January 2019
2 Reads

The risk of hypertension doubles every ten years in China: Age, period and birth cohort effects on the prevalence of hypertension from 2004 to 2013.

Am J Hypertens 2019 Jan 19. Epub 2019 Jan 19.

Department of Epidemiology, School of Basic Medicine, Jinan University, Guangzhou, Guangdong, China.

Background: Hypertension is a growing problem worldwide and can often result in a variety of negative health outcomes. The aim of this study was to assess the effects of age at diagnosis, calendar period, and birth cohort on the change in the prevalence rate of hypertension in Guangzhou from 2004 to 2013.

Methods: We utilized data from the Guangzhou Community Health Survey (GCHS), a population-based study designed by the National Health and Family Planning Commission of the PRC every five years. Read More

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http://dx.doi.org/10.1093/ajh/hpz003DOI Listing
January 2019
2 Reads

Schedules for Self-monitoring Blood Pressure: A Systematic Review.

Am J Hypertens 2019 Jan 22. Epub 2019 Jan 22.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

Background: Self-monitoring of blood pressure better predicts prognosis than clinic measurement, is popular with patients, and endorsed in hypertension guidelines. However, there is uncertainty over the optimal self-monitoring schedule. We therefore aimed to determine the optimum schedule to predict future cardiovascular events and determine "true" underlying blood pressure. Read More

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http://dx.doi.org/10.1093/ajh/hpy185DOI Listing
January 2019

Impacts of the New 2017 ACC/AHA Hypertension Guideline on the Prevalence of Brachial Hypertension and Its Concordance with Central Hypertension.

Am J Hypertens 2019 Jan 18. Epub 2019 Jan 18.

Department of Medical Education, Taipei, Taiwan.

Objectives: The 2017 American College of Cardiology/American Heart Association (ACC/AHA) guideline lowers the blood pressure (BP) thresholds for defining brachial hypertension. We therefore aimed to investigate how the new guideline influences the prevalence of brachial hypertension and whether it improves the identification of central hypertension in an Asian national representative population.

Methods: A total of 2742 adults older than 19 years participated in the 2013-2016 National Nutrition and Health Survey in Taiwan. Read More

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http://dx.doi.org/10.1093/ajh/hpz008DOI Listing
January 2019
4 Reads

Maternal gestational diabetes is associated with offspring's hypertension.

Am J Hypertens 2019 Jan 9. Epub 2019 Jan 9.

Pennington Biomedical Research Center, Baton Rouge, LA.

Objective: Several studies assessed maternal gestational diabetes mellitus (GDM) with the risk of childhood high blood pressure, and the results were inconsistent. We investigated the association between maternal GDM and high blood pressure risk in offspring during early childhood.

Methods: We performed a large study in 1156 mother-child pairs (578 GDM and 578 non-GDM matched by their offspring's age and sex). Read More

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http://dx.doi.org/10.1093/ajh/hpz005DOI Listing
January 2019
11 Reads
2.852 Impact Factor

Added value of aortic pulse wave velocity index in a predictive diagnosis decision tree of coronary heart disease.

Am J Hypertens 2019 Jan 9. Epub 2019 Jan 9.

Paris-Descartes University; Diagnosis and Therapeutic Center, Hypertension and Cardiovascular Prevention Unit, Hôtel-Dieu Hospital; AP-HP, Paris, France.

Background: Coronary heart disease (CHD) is among the main causes of death in the world. Individual study of cardiovascular risk is an important way to a predict CHD risk. The aim of this study was to evaluate the added role of the aortic pulse wave velocity (PWV) index in the prediction of CHD risk. Read More

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https://academic.oup.com/ajh/advance-article/doi/10.1093/ajh
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http://dx.doi.org/10.1093/ajh/hpz004DOI Listing
January 2019
4 Reads

Serum lipids and risk of rapid renal function decline in treated hypertensive adults with normal renal function.

Am J Hypertens 2019 Jan 5. Epub 2019 Jan 5.

National Clinical Research Center for Kidney Disease; State Key Laboratory for Organ Failure Research; Renal Division, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Background: We aim to evaluate the effect of different lipids parameters, including triglycerides (TG), high density lipoprotein cholesterol (HDL-C), the TG to HDL-C (TG: HDL-C) ratio, total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C), on the risk of rapid renal function decline and examine any possible effect modifiers in general hypertensive patients with normal renal function.

Methods: A total of 12,549 hypertensive patients with eGFR ≥60ml/min/1.73m 2 in the renal sub-study of the China Stroke Primary Prevention Trial (CSPPT) were included in the analyses. Read More

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http://dx.doi.org/10.1093/ajh/hpz001DOI Listing
January 2019
3 Reads

How many measurements?

Am J Hypertens 2019 Jan 3. Epub 2019 Jan 3.

Lauder Cardiovascular Center Icahn School of Medicine at Mount Sinai, New York.

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http://dx.doi.org/10.1093/ajh/hpz002DOI Listing
January 2019
1 Read

Assessing the Impact of Patient-Centered Medical Home Principles on Hypertension Outcomes among Patients of HRSA Funded Health Centers.

Am J Hypertens 2018 Dec 24. Epub 2018 Dec 24.

Bureau of Primary Health Care, Health Resources and Services Administration, Department of Health and Human Services, Rockville, MD, USA.

Background: Millions of Americans have uncontrolled hypertension and are low-income or uninsured. Health Resources and Services Administration-funded health centers (HCs) are primary providers of care to these patients and a majority have adopted the Patient-Centered Medical Home (PCMH). PCMH includes principles of care coordination or integration and care management-support important to the treatment of hypertension. Read More

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http://dx.doi.org/10.1093/ajh/hpy198DOI Listing
December 2018
10 Reads

Towards Individualized Blood Pressure Management After Stroke.

Am J Hypertens 2019 Feb;32(3):242-244

Division of Neurocritical Care & Emergency Neurology and Vascular Neurology, Department of Neurology, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1093/ajh/hpy192DOI Listing
February 2019
1 Read

The Interaction of a Diabetes Gene Risk Score With Three Different Antihypertensive Medications for Incident Glucose Level Elevation.

Am J Hypertens 2018 Dec 26. Epub 2018 Dec 26.

Department of Epidemiology, University of Kentucky College of Public Health, Lexington, KY.

Background: Elevations of fasting glucose (FG) levels are frequently encountered in people treated with thiazide diuretics. The risk is lower in people treated with ACE inhibitors (ACEi). To determine if genetic factors play a role in FG elevation we examined the interaction of a diabetes gene risk score (GRS) with the use of three different antihypertensive medications. Read More

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http://dx.doi.org/10.1093/ajh/hpy199DOI Listing
December 2018
1 Read

Lower systolic blood pressure and cardiovascular event risk stratified by renal resistive index in hospitalized cardiovascular patients: J-VAS study.

Am J Hypertens 2018 Dec 16. Epub 2018 Dec 16.

Division of Cardiovascular Medicine, Jichi Medical University School of Medicine, Japan.

Background: The threshold of blood pressure (BP) reduction in cardiovascular patients is debatable due to the J-shaped curve phenomenon, which is particularly observed in patients with increased arterial stiffness. The renal resistive index (RRI) correlates well with systemic arterial stiffness; therefore, we aimed to demonstrate the role of RRI in guiding the choice of optimal BP.

Methods: A retrospective analysis of prospectively collected data of the hospitalized cardiovascular patients at Jichi Medical University Hospital. Read More

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https://academic.oup.com/ajh/advance-article/doi/10.1093/ajh
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http://dx.doi.org/10.1093/ajh/hpy189DOI Listing
December 2018
1 Read

3-Bromopyruvate attenuates experimental pulmonary hypertension via inhibition of glycolysis.

Am J Hypertens 2018 Dec 18. Epub 2018 Dec 18.

Department of Cardio-Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.

Background: The shift of metabolism from mitochondrial oxidative phosphorylation to glycolysis and mitochondria binding partner of hexokinase are features common to cancer. These have been seen in pulmonary hypertension (PH) as well. An inhibitor of hexokinase 2 (HK 2), the small molecule 3-bromopyruvate (3-BrPA) is incredibly powerful and swift acting anticancer agent. Read More

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http://dx.doi.org/10.1093/ajh/hpy191DOI Listing
December 2018
9 Reads

Xanthine Oxidase Inhibition as a Potential Treatment for Aortic Stiffness in Hypertension.

Am J Hypertens 2019 Feb;32(3):234-236

Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University.

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http://dx.doi.org/10.1093/ajh/hpy197DOI Listing
February 2019
1 Read

Uromodulin in a pathway between decreased renal urate excretion and albuminuria.

Am J Hypertens 2018 Dec 14. Epub 2018 Dec 14.

Centre de recherche du CHUM, Montréal, Quebec, Canada.

Background: The mechanism explaining the inverse association between renal urate and albumin excretion remains unclear. First, we evaluated the impact of candidate variants in the main urate transporter genes (i.e. Read More

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http://dx.doi.org/10.1093/ajh/hpy190DOI Listing
December 2018
2 Reads

Nonlinear Relationship Between Blood Pressure and Glaucoma in US Adults.

Am J Hypertens 2019 Feb;32(3):308-316

Department of Medicine and Program in Public Health, University of California, Irvine, Irvine, California, USA.

Background: Previous studies have reported that vascular disease is associated with glaucoma. However, the relationship between blood pressure (BP) and glaucoma has been inconsistent. We investigated whether there is a nonlinear association between BP and glaucoma in an adult population of the United States. Read More

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https://academic.oup.com/ajh/advance-article/doi/10.1093/ajh
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http://dx.doi.org/10.1093/ajh/hpy186DOI Listing
February 2019
11 Reads
2.852 Impact Factor

Electrocardiographic ST-T Area Assessed by a Computerized Quantitative Method and Its Relation to Cardiovascular Events: The J-HOP Study.

Am J Hypertens 2019 Feb;32(3):282-288

Department of Medicine, Division of Cardiovascular Medicine, School of Medicine, Jichi Medical University, Tochigi, Japan.

Background: Although many studies have reported that the presence of minor or major ST-T change of electrocardiography (ECG) was associated with a risk of cardiovascular events, it is not clear whether there is a difference in the prognostic power depending on the summation of ST-T area (ST-Tarea) assessed by a quantitative method.

Methods: Electrocardiograms were performed in 834 clinical patients with one or more cardiovascular risks. ST-Tarea was assessed as the area enclosed by the baseline from the end of the QRS complex to the end of the ST-T segment using a computerized quantitative method. Read More

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https://academic.oup.com/ajh/advance-article/doi/10.1093/ajh
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http://dx.doi.org/10.1093/ajh/hpy180DOI Listing
February 2019
2 Reads

Carotid Artery Blood Flow Velocities and Cognitive Performance: Forecasting Cognitive Decline.

Am J Hypertens 2019 Feb;32(3):237-239

Department of Behavioral Health and Nutrition, College of Health Sciences, University of Delaware, Newark, DE, USA.

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http://dx.doi.org/10.1093/ajh/hpy184DOI Listing
February 2019
1 Read

Inverse relationship between coarse food grain intake and blood pressure among young Chinese adults.

Am J Hypertens 2018 Dec 8. Epub 2018 Dec 8.

Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.

Background: Coarse food grains are rich in dietary fiber and contain a wide range of nutrients with potential health benefits, such as blood pressure control. Coarse food grains are very popular in China, where hypertension is a major challenge. We evaluated the associations between coarse food grain consumption and blood pressure among young Chinese adults. Read More

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http://dx.doi.org/10.1093/ajh/hpy187DOI Listing
December 2018
3 Reads

Backward in Coming Forward.

Am J Hypertens 2019 Feb;32(3):240-241

Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1093/ajh/hpy188DOI Listing
February 2019
1 Read

Arterial Stiffness and Blood Pressure in a Multicultural Child Sample (Angola, Brazil, and Spain).

Am J Hypertens 2019 Feb;32(3):265-271

Department of Nutrition, Federal University of Espírito Santo, Brazil.

Background: To analyze the relationship between early-life indicators, blood pressure (BP), and arterial stiffness in childhood, in three samples with different bio-cultural characteristics.

Methods: The total sample included 520 schoolchildren 9-10 years of age from Madrid (Spain), Vitória (Brazil), and Luanda (Angola). Height and weight, BP, and carotid-femoral pulse wave velocity (cf-PWV) were measured, all by one observer in each site, and body mass index (BMI) was calculated. Read More

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https://academic.oup.com/ajh/advance-article/doi/10.1093/ajh
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http://dx.doi.org/10.1093/ajh/hpy182DOI Listing
February 2019
2 Reads

When Office Blood Pressure Is Not Enough: The Case of Masked Hypertension.

Am J Hypertens 2019 Feb;32(3):225-233

Department of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy.

An increasing attention has been devoted in the last two decades to masked hypertension (MH), a condition characterized by the fact that classification of a normal blood pressure (BP) status by office measurements is not confirmed by home and/or ambulatory BP monitoring (ABPM). MH definition (i.e. Read More

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http://dx.doi.org/10.1093/ajh/hpy183DOI Listing
February 2019
1 Read

Accuracy Validation of 8 Equations to Estimate 24-Hour Sodium by Spot Urine in Young Adolescents.

Am J Hypertens 2019 Feb;32(3):257-264

Department of Epidemiology, Capital Institute of Pediatrics, Beijing, China.

Background: Several formulas using spot urine have been developed to estimate 24-hour sodium excretion, but none of them have been validated in pediatrics. We aimed to evaluate the performance of 8 formulas-Kawasaki; Tanaka; International Cooperative Study on Salt, Other Factors, and Blood Pressure (INTERSALT1); INTERSALT without potassium (INTERSALT2); Mage; Whitton; Uechi simple-mean; and Uechi regression-in estimating 24-hour sodium excretion at both population and individual levels in Chinese young adolescents.

Methods: This cross-sectional study consisted of 284 students aged 10-15 years from Hunan, China. Read More

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http://dx.doi.org/10.1093/ajh/hpy178DOI Listing
February 2019
1 Read

Association of Periodontal Disease and Edentulism With Hypertension Risk in Postmenopausal Women.

Am J Hypertens 2019 Jan;32(2):193-201

Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, State University of New York, Buffalo, New York, USA.

Background: Multiple cross-sectional epidemiologic studies have suggested an association between periodontal disease and tooth loss and hypertension, but the temporality of these associations remains unclear. The objective of our study was to evaluate the association of baseline self-reported periodontal disease and edentulism with incident hypertension.

Methods: Study participants were 36,692 postmenopausal women in the Women's Health Initiative-Observational Study who were followed annually from initial periodontal assessment (1998-2003) through 2015 (mean follow-up 8. Read More

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https://academic.oup.com/ajh/advance-article/doi/10.1093/ajh
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http://dx.doi.org/10.1093/ajh/hpy164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331709PMC
January 2019
10 Reads

Beet Juice as Nutraceutical Remedy for Alleviating Pulmonary Arterial Hypertension: Searching for Optimal Treatment Timing and Nitrate Dose.

Authors:
Lei Xi

Am J Hypertens 2019 Jan;32(2):135-138

Pauley Heart Center, Division of Cardiology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.

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http://dx.doi.org/10.1093/ajh/hpy181DOI Listing
January 2019
1 Read
2.852 Impact Factor

How to Improve Patients' Adherence to Antihypertensive Therapy: A Simple Solution for a Big Trouble.

Am J Hypertens 2019 Jan;32(2):141-142

Hypertension Unit, Division of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, University of Rome Sapienza, Sant'Andrea Hospital, Rome, Italy.

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http://dx.doi.org/10.1093/ajh/hpy179DOI Listing
January 2019
1 Read

Organ-Specific, Age-Dependent Associations of Steady-State Pressures and Pulsatile Pressure Wave Components With End-Organ Measures.

Am J Hypertens 2019 Feb;32(3):272-281

Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Background: The contribution of steady-state pressures and the forward (Pf) and backward (reflected) (Pb) wave pressure components of pulse pressure to risk prediction have produced contrasting results. We hypothesized that the independent contribution of steady-state pressures (mean arterial pressure [MAP]), Pf and Pb, to cardiovascular damage is organ specific and age dependent.

Methods: In 1,384 black South Africans from a community sample, we identified independent relations between MAP, Pf, or Pb (applanation tonometry and SphygmoCor software) and left ventricular mass index (LVMI) (n = 997) (echocardiography), carotid intima-media thickness (IMT) (n = 804) (B-mode ultrasound), or aortic pulse wave velocity (PWV) (n = 1,217). Read More

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http://dx.doi.org/10.1093/ajh/hpy171DOI Listing
February 2019
1 Read

Impact of Hypertension on Hospitalizations for Cardiovascular Diseases in a Worksite Population: An Epidemiologic Study Using Claims Data for Workers.

Am J Hypertens 2019 Feb;32(3):298-307

Health Economics and Outcomes Research, Creativ-Ceutical, Paris, France.

Background: Few of studies investigated the effect of antihypertensives among working population. We aimed to describe the impact of hypertension with and without antihypertensives on hospitalizations because of cardiovascular diseases (CVDs) in the Japanese working population.

Methods: This retrospective study included adults aged 40-64 years whose systolic and diastolic blood pressure (BP) readings taken between 2008 and 2015 were available in the Japanese claims database. Read More

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http://dx.doi.org/10.1093/ajh/hpy177DOI Listing
February 2019
1 Read

Maternal hypertensive disorders of pregnancy and offspring risk of hypertension: a population-based cohort and sibling study.

Am J Hypertens 2018 Nov 24. Epub 2018 Nov 24.

Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Clinical Sciences Malmö, Lund University, Malmö, Sweden.

Background: Women with a history of hypertensive disorders of pregnancy (HDP) are at increased risk of hypertension, cardiovascular disease, and type 2 diabetes. Offspring from pregnancies complicated by HDP also have worse cardiometabolic status in childhood and young adulthood, but the offspring risk of clinical hypertension in adulthood is largely unknown.

Methods: We studied 13,893 first-born adult offspring (49. Read More

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https://academic.oup.com/ajh/advance-article/doi/10.1093/ajh
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http://dx.doi.org/10.1093/ajh/hpy176DOI Listing
November 2018
7 Reads

Speckle-Tracking Echocardiographic Layer-Specific Strain Analysis on Subclinical Left Ventricular Dysfunction in Patients With Primary Aldosteronism.

Am J Hypertens 2019 Jan;32(2):155-162

The Shanghai Institute of Hypertension, Department of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Background: Primary aldosteronism (PA) may cause myocardial injury. We investigated myocardial dysfunction using speckle-tracking echocardiographic (STE) layer-specific strain in patients with PA.

Methods: Our study included 62 patients with PA (33 aldosterone-producing adenoma [APA] and 29 idiopathic hyperaldosteronism [IHA]) and 30 patients with primary hypertension. Read More

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http://dx.doi.org/10.1093/ajh/hpy175DOI Listing
January 2019
4 Reads
2.852 Impact Factor

Time to First Cigarette and the Risk of Hypertension: A Nationwide Representative Study in Korea.

Am J Hypertens 2019 Jan;32(2):202-208

Department of Family Medicine, Pusan National University Hospital, Busan, South Korea.

Background: Although previous studies have explored the effect of smoking on blood pressure, little is still known about the role of time to first cigarette (TTFC)-an indicator of nicotine dependence-in hypertension. Therefore, we evaluated this association using representative nationwide data.

Methods: Current daily smokers (N = 941; aged 19-79 years) who participated in the 7th version of the Korea National Health and Nutrition Examination Survey I (2016) were included. Read More

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https://academic.oup.com/ajh/advance-article/doi/10.1093/ajh
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http://dx.doi.org/10.1093/ajh/hpy170DOI Listing
January 2019
15 Reads

Systolic Blood Pressure Trajectories in the Acute Phase and Clinical Outcomes in 2-Year Follow-up Among Patients With Ischemic Stroke.

Am J Hypertens 2019 Feb;32(3):317-325

Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.

Background: Optimal blood pressure (BP) levels during acute ischemic stroke have not been established. We studied associations between systolic BP trajectories during acute phase and subsequent clinical outcomes among patients with ischemic stroke.

Methods: A total of 4,036 patients with acute ischemic stroke and elevated BP from the China Antihypertensive Trial in Acute Ischemic Stroke trial were included in this analysis. Read More

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http://dx.doi.org/10.1093/ajh/hpy174DOI Listing
February 2019
2 Reads
2.852 Impact Factor

Heart-to-Brachium Pulse Wave Velocity as a Measure of Proximal Aortic Stiffness: MRI and Longitudinal Studies.

Am J Hypertens 2019 Jan;32(2):146-154

Department of Kinesiology and Health Education, The University of Texas at Austin, Austin, Texas, USA.

Background: Stiffening of the proximal aorta is associated with heightened cardiovascular disease risks but can be quantified by limited methodologies (e.g., magnetic resonance imaging [MRI]). Read More

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/ajh/hpy166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331710PMC
January 2019
10 Reads

Effect Modification by Age on the Benefit or Harm of Antihypertensive Treatment for Elderly Hypertensives: A Systematic Review and Meta-analysis.

Am J Hypertens 2019 Jan;32(2):163-174

Center for Evidence-based Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

Background: The influence of age on balance of benefit vs. potential harm of blood pressure (BP)-lowering therapy for elderly hypertensives is unclear. We evaluated the modifying effects of age on BP lowering for various adverse outcomes in hypertensive patients older than 60 years without specified comorbidities. Read More

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http://dx.doi.org/10.1093/ajh/hpy169DOI Listing
January 2019
2 Reads

Multi-Segment Indexes of Arterial Stiffness Show Lower Repeatability Than Carotid-Femoral Pulse Wave Velocity or Systolic Blood Pressure.

Am J Hypertens 2019 Feb;32(3):245-248

Exercise Physiology Lab, Institute of Human Movement Sciences and Sport, ETH Zurich, Zurich, Switzerland.

Background: We investigated the inter-day repeatability of newly proposed indexes of cardiovascular health based on the absolute (PWVABS) or relative (PWVRATIO) difference in pulse wave velocity (PWV) between the carotid-femoral (PWVCF) and carotid-radial (PWVCR) segments compared with PWVCF alone and with systolic blood pressure (BPSYST) over multiple days.

Methods: All variables were measured in triplicates in a group of 16 young, healthy individuals (8 men/8 women, body mass 66 ± 14 kg, height 1.7 ± 0. Read More

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https://academic.oup.com/ajh/advance-article/doi/10.1093/ajh
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http://dx.doi.org/10.1093/ajh/hpy167DOI Listing
February 2019
9 Reads

Genetic Polymorphisms in Hypertension: Are We Missing the Immune Connection?

Am J Hypertens 2019 Jan;32(2):113-122

Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

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https://academic.oup.com/ajh/advance-article/doi/10.1093/ajh
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http://dx.doi.org/10.1093/ajh/hpy168DOI Listing
January 2019
10 Reads

Resistant Hypertension: An Update.

Am J Hypertens 2019 Jan;32(1):1-3

Division of General Medicine, Hypertension Section, Department of Medicine, Springfield, Illinois, USA.

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http://dx.doi.org/10.1093/ajh/hpy156DOI Listing
January 2019
2 Reads

Eye Clinic as a Potential Site to Measure Blood Pressure.

Authors:
Audrey Adji

Am J Hypertens 2019 Jan;32(1):12-14

Department of Cardiology, St Vincent's Clinic, Sydney, Australia.

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https://academic.oup.com/ajh/advance-article/doi/10.1093/ajh
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http://dx.doi.org/10.1093/ajh/hpy161DOI Listing
January 2019
8 Reads