1,216 results match your criteria American journal of Alzheimer's disease and other dementias[Journal]


Cognitive Function of Elderly Persons in Japanese Neighborhoods: The Role of Street Layout.

Am J Alzheimers Dis Other Demen 2019 Apr 21:1533317519844046. Epub 2019 Apr 21.

1 Faculty of Sport Sciences, Waseda University, Tokorozawa, Japan.

Objectives: The aims of this study were to examine (a) associations of two metric and space syntax measures of street layout with the cognitive function of Japanese older adults and (b) the extent to which objectively assessed physical activity mediated such associations.

Methods: Cross-sectional data from 277 older adults who lived in Japan were used. Street layout attributes were objectively calculated for each participant's geocoded home location. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317519844046DOI Listing

Intravenous Immunoglobulin for Patients With Alzheimer's Disease: A Systematic Review and Meta-Analysis.

Am J Alzheimers Dis Other Demen 2019 Apr 15:1533317519843720. Epub 2019 Apr 15.

1 Clinical Research and Evidence-Based Medicine Unit, Second Medical Department, Aristotle University of Thessaloniki, Hippokration General Hospital, Thessaloniki, Greece.

Aim: To assess the efficacy and safety of intravenous immunoglobulin (IVIg) for patients with Alzheimer's disease (AD).

Materials And Methods: We searched electronic databases and other sources for randomized controlled trials comparing IVIg with placebo or other treatment for adults with AD. Primary outcome was change from baseline in Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317519843720DOI Listing

Do Nursing Home Residents With Dementia Receive Pain Interventions?

Am J Alzheimers Dis Other Demen 2019 May;34(3):193-198

3 New York State Department of Health, Bureau of Environmental & Occupational Epidemiology, Albany, NY, USA.

This study compares pain interventions received by nursing home residents with and without dementia. Secondary data analyses of cross-sectional data from 50,673 nursing home residents in New York State were collected by the Minimum Data Set 3.0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317519840506DOI Listing

Efficacy and Limitations of rCBF-SPECT in the Diagnosis of Alzheimer's Disease With Amyloid-PET.

Am J Alzheimers Dis Other Demen 2019 Apr 9:1533317519841192. Epub 2019 Apr 9.

1 Division of Nuclear Medicine, Department of Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

This study aimed to assess efficacy and limitations of regional cerebral blood flow imaging using single-photon emission computed tomography (rCBF-SPECT) in the diagnosis of Alzheimer's disease (AD) with amyloid-positron emission tomography (amyloid-PET). Thirteen patients, who underwent both rCBF-SPECT and amyloid-PET after clinical diagnosis of AD or mild cognitive impairment, were retrospectively identified. The rCBF-SPECTs were classified into 4 grades, from typical AD pattern to no AD pattern of hypoperfusion; amyloid-beta (Aβ) positivity was assessed by amyloid-PET. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317519841192DOI Listing
April 2019
3 Reads

Impact of Coexisting Overactive Bladder in Medicare Patients With Dementia on Clinical and Economic Outcomes.

Am J Alzheimers Dis Other Demen 2019 Apr 9:1533317519841164. Epub 2019 Apr 9.

3 Humana Inc, Cincinnati, OH, USA.

Background: Patients with dementia commonly suffer from symptoms of overactive bladder (OAB); however, limited research exists on the clinical impact of coexisting OAB among patients with dementia. As such, the objective of this study was to examine the impact of OAB on clinical outcomes, health-care resource use, and associated costs among patients with dementia.

Methods: We conducted a retrospective cohort analysis of patients with dementia using 3861 matched pairs of patients with and without OAB. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317519841164DOI Listing

Prevalence and Severity of Neuropsychiatric Symptoms in Early- Versus Late-Onset Alzheimer's Disease.

Am J Alzheimers Dis Other Demen 2019 Apr 1:1533317519841191. Epub 2019 Apr 1.

1 Department of Health Sciences, University of Leicester, Leicester, United Kingdom.

Background:: The study aimed to compare neuropsychiatric symptoms (NPS) in people with early-onset Alzheimer's disease (EOAD) and late-onset AD (LOAD).

Methods:: Fifty-six participants with LOAD and 24 participants with EOAD having mild dementia were assessed for NPS for their frequency, severity, and caregiver distress as measured by Neuropsychiatry Inventory (NPI) along with assessments of cognition and functional dependence.

Results:: Participants with EOAD and LOAD were not significantly different for total NPI score ( P = . Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317519841191DOI Listing
April 2019
7 Reads

How to Assess Executive Functions in a Low-Educated and Multicultural Population Using a Switching Verbal Fluency Test (the TFA-93) in Neurodegenerative Diseases?

Am J Alzheimers Dis Other Demen 2019 Mar 3:1533317519833844. Epub 2019 Mar 3.

1 Equipe Neuropsychologie du Vieillissement (EA 4468), Institut de Psychologie, Université Paris Descartes, Boulogne-Billancourt, France.

Few neuropsychological tests are available to assess executive dysfunction in low-educated and multicultural populations. To address this issue, the TFA-93, a switching verbal fluency test to assess cognitive flexibility, was administered to 70 healthy controls, 57 patients with a clinical diagnosis of Alzheimer's disease, and 21 with a clinical diagnosis of a neurodegenerative disease associated with frontal disorders. Most of the participants were low-educated and nonnative French speakers. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1533317519833844
Publisher Site
http://dx.doi.org/10.1177/1533317519833844DOI Listing
March 2019
5 Reads

Excessive Daytime Sleepiness in Major Dementia Syndromes.

Am J Alzheimers Dis Other Demen 2019 Feb 10:1533317519828046. Epub 2019 Feb 10.

1 Mayo Clinic, Rochester, MN, USA.

There has been no comparison of excessive daytime sleepiness (EDS) in patients with Alzheimer's disease dementia (AD), dementia with Lewy bodies (DLB), and behavioral variant frontotemporal dementia (bvFTD). We identified patients with mild dementia who met criteria for these disorders who also had the Epworth Sleepiness Scale (ESS) completed. The sample included 17 bvFTD, 111 AD, and 31 DLB. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317519828046DOI Listing
February 2019
1 Read

New-Onset Alzheimer's Disease and Normal Subjects 100% Differentiated by P300.

Am J Alzheimers Dis Other Demen 2019 Feb 7:1533317519828101. Epub 2019 Feb 7.

3 Neuroptics Med Clinic, Bucharest, Romania.

Previous work has suggested that evoked potential analysis might allow the detection of subjects with new-onset Alzheimer's disease, which would be useful clinically and personally. Here, it is described how subjects with new-onset Alzheimer's disease have been differentiated from healthy, normal subjects to 100% accuracy, based on the back-projected independent components (BICs) of the P300 peak at the electroencephalogram electrodes in the response to an oddball, auditory-evoked potential paradigm. After artifact removal, clustering, selection, and normalization processes, the BICs were classified using a neural network, a Bayes classifier, and a voting strategy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317519828101DOI Listing
February 2019
1 Read

Predictors of Symptoms Remission Among Family Caregivers of Individuals With Dementia Receiving REACH VA.

Am J Alzheimers Dis Other Demen 2019 Feb 5:1533317519826241. Epub 2019 Feb 5.

1 VA New York Harbor Healthcare System, New York, NY, USA.

Resources for Enhancing All Caregivers Health (REACH VA) is a behavioral intervention for caregivers of individuals with dementia disseminated in the VA. Although shown to improve caregiver and care recipient outcomes, some caregivers continue to experience depression or caregiver burden following the intervention. Factors that predict symptom remission following REACH VA are unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317519826241DOI Listing
February 2019
7 Reads

Constant Observation Practices for Hospitalized Persons With Dementia: A Survey Study.

Am J Alzheimers Dis Other Demen 2019 Jan 31:1533317519826272. Epub 2019 Jan 31.

6 Department of Medicine, Division of Geriatrics and Palliative Medicine, Northwell Health, New York, NY, USA.

Despite substantial staffing and cost implications, the use of constant observation (CO) has been poorly described in the acute care setting. The purpose of this cross-sectional, multicenter, survey study was to assess hospital provider practices regarding the use of CO. Of the 543 surveys distributed, 231 were completed across 5 sites. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317519826272DOI Listing
January 2019

Specific Association Between Religiosity and Cognitive Functions in Alzheimer's Disease.

Am J Alzheimers Dis Other Demen 2019 Jan 31:1533317519827416. Epub 2019 Jan 31.

1 Department of Psychiatry, Hallym University College of Medicine, Chuncheon, Republic of Korea.

Objectives:: This study aimed to identify the specific relationship between subdomains of religious variables and cognitive functions in outpatients with Alzheimer's disease (AD).

Methods:: We recruited 325 patients with AD from a psychiatry outpatient clinic. The Korean version of the Consortium to Establish a Registry for Alzheimer's Disease and the Duke University Religion Index were used to assess cognitive functions and religiosity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317519827416DOI Listing
January 2019

Caregiver Burden and Desire for Institutional Placement-The Roles of Positive Aspects of Caregiving and Religious Coping.

Am J Alzheimers Dis Other Demen 2019 May 30;34(3):199-207. Epub 2019 Jan 30.

1 The University of Texas at Arlington, School of Social Work, Arlington, TX, USA.

Based on stress coping theory, this study investigated whether and how positive aspects of caregiving (PAC) and religiosity buffered the association between caregiving burden and desire to institutionalize (DTI). Secondary data (N = 637) were drawn from the baseline assessment of the Resources for Enhancing Alzheimer's Caregiver Health II project. Descriptive analysis, bivariate correlation, and multiple linear regressions were conducted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317519826217DOI Listing

Links Between Painting and Neurology: The Example of Dementia.

Am J Alzheimers Dis Other Demen 2019 Jan 30:1533317519826293. Epub 2019 Jan 30.

2 Psychiatry Unit, Versilia Hospital, Lido di Camaiore, Lucca, Italy.

Art is a system of human communication arising from symbolic cognition, conveying ideas, experiences, and feelings. The goal of this review is to describe the link between painting and dementia. Individuals with neurodegenerative diseases inevitably experience cognitive dysfunction that has the potential to limit and impair the artist's ability to realize their creative and expressive intentions through painting. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1533317519826293
Publisher Site
http://dx.doi.org/10.1177/1533317519826293DOI Listing
January 2019
3 Reads
1.426 Impact Factor

Telephone-Based Cognitive Behavioral Intervention Improves Dementia Caregivers' Quality of Life.

Am J Alzheimers Dis Other Demen 2019 Jan 13:1533317518822100. Epub 2019 Jan 13.

1 Department of Counseling and Clinical Intervention, Institute of Psychology, Friedrich Schiller University Jena, Jena, Germany.

The present study examined the effects of a telephone-based cognitive behavioral intervention on dementia caregivers' quality of life (QoL). A total of 273 caregivers were randomly assigned to an intervention or control group. The intervention comprised 12 telephone sessions of individual cognitive behavioral therapy (CBT) over 6 months. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518822100DOI Listing
January 2019

Effect of Vitamin D on Cognitive Functions in Older Adults: 24-Week Follow-Up Study.

Am J Alzheimers Dis Other Demen 2019 Jan 1:1533317518822274. Epub 2019 Jan 1.

1 Department of Geriatric Medicine, Dokuz Eylul University, Faculty of Medicine, Izmir, Turkey.

The purpose of this study is to assess the effect of vitamin D replacement on cognitive function in older adults. A total of 560 patients who underwent comprehensive geriatric assessment including Global cognitive assessment, Basic Activities of Daily Living (BADL), and Instrumental Activities of Daily Living (IADL) twice in 6-month period were retrospectively reviewed. Oral cholecalciferol was replaced to patients with vitamin D deficiency routinely. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518822274DOI Listing
January 2019

Seizure in Alzheimer's Disease: An Underestimated Phenomenon.

Am J Alzheimers Dis Other Demen 2018 Dec 30:1533317518813551. Epub 2018 Dec 30.

3 Tehran University of Medical Sciences, Tehran, Iran.

Alzheimer's disease (AD) is considered as a potential risk factor for the development of seizure due to neurodegeneration and imbalance between stimulatory and inhibitory circuits in the brain. Seizure could occur in any point during the course of AD, and its presentation varies from fluctuation in cognitive domains to more typical seizures. The clinical diagnosis of seizure in patients with dementia may be challenging due to difficulty in history taking and clinical assessment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518813551DOI Listing
December 2018
6 Reads

Do Caregiver Characteristics Affect Caregiver Burden Differently in Different Countries?

Am J Alzheimers Dis Other Demen 2019 May 30;34(3):148-152. Epub 2018 Dec 30.

6 Department of Psychiatry and Psychotherapy, Centre of Health Services Research in Medicine, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.

The relationships between caregiver burden as measured with the Burden Scale for Family Caregivers-short form and 6 characteristics of caregivers caring for patients with dementia were investigated for caregivers from England (n = 36), Finland (n = 42), and Greece (n = 46) using survey data. In all 3 countries, caregiver burden increases with physical problems of the caregiver, emotional problems of the caregiver, and weekly hours of care. Hence, in all 3 countries, special support for informal care is required when these characteristics are at high levels. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518822047DOI Listing

Evolution of Dementia Related to the Use of Alcohol in the French Nationwide Discharge Summary Database Between 2007 and 2017.

Am J Alzheimers Dis Other Demen 2019 May 30;34(3):188-192. Epub 2018 Dec 30.

1 Univ. Lille, Lille, France.

Background: The French nationwide exhaustive hospital discharge database (PMSI) is used for activity-based payment of hospital services. We hypothesized that the release of articles about alcohol and dementia could influence the identification of these diagnoses in PMSI.

Methods: We analyzed temporal evolution of coding for dementia and other persistent or late-onset cognitive impairment (OPLOCI) due to alcohol and other psychoactive substances in the PMSI database from 2007 to 2017 (285 748 938 inpatient stays). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518822043DOI Listing
May 2019
1 Read

Empowering Patients with Alzheimer's Disease To Avoid Unwanted Medical Care: A Look At The Dementia Care Triad.

Am J Alzheimers Dis Other Demen 2018 Dec 13:1533317518817614. Epub 2018 Dec 13.

4 New York State Department of Health, Albany, NY, USA.

Patients with Alzheimer's disease and other types of dementia with acute medical problems, who have lost capacity and are without advance directives, are at risk of being over treated inhospitals. To deal with this growing demographic and ethical crisis, patients with dementia need to plan for their future medical care while they have capacity to do so. This article will examine the role of each member of the dementia care triad and how to empower the patient to participate in planning future medical care. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518817614DOI Listing
December 2018

Feasibility and Impact of a Multicomponent Exercise Intervention in Patients With Alzheimer's Disease: A Pilot Study.

Am J Alzheimers Dis Other Demen 2019 Mar 9;34(2):95-103. Epub 2018 Dec 9.

1 CIAFEL-Research Centre in Physical Activity, Health and Leisure, Porto, Portugal.

This quasi-experimental, nonrandomized study examined the feasibility and impact of a multicomponent (MT) intervention on 7 community-dwelling individuals diagnosed with probable Alzheimer's disease (AD) at mild to moderate stage. During 6 months, patients with AD and their caregivers were submitted to a biweekly exercise program, including muscle strengthening, aerobics, balance, and postural exercises. The following tests were used: Senior Fitness Test and Incremental Treadmill Test, Disability Assessment for Dementia Scale, Alzheimer Disease Assessment Scale-Cognitive, and Quality of Life-Alzheimer's. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518813555DOI Listing
March 2019
2 Reads

A Comparative Single-Blind Randomized Controlled Trial With Language Training in People With Mild Cognitive Impairment.

Am J Alzheimers Dis Other Demen 2019 May 5;34(3):176-187. Epub 2018 Dec 5.

1 Greek Alzheimer Association, Thessaloniki, Greece.

Background: Although cognitive training is effective for people with mild cognitive impairment (MCI), it is not clear which format is more effective.

Objective: To compare the effectiveness of the same language programs when carried out via computer, paper/pencil and orally in people with MCI.

Methods: Seventy-one participants with MCI were randomly classified in 3 experimental and 2 control groups. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518813554DOI Listing
May 2019
19 Reads

Relationships Between Cognitive Dysfunction and Health-Related Quality of Life Among Older Persons in Taiwan: A Nationwide Population-Based Survey.

Am J Alzheimers Dis Other Demen 2019 Feb 5;34(1):41-48. Epub 2018 Dec 5.

9 School of Nursing, College of Medicine, Chang Gung University, Taoyuan, Taiwan.

Background:: To examine the relationships between cognitive dysfunction status and quality of life.

Methods:: Secondary analysis of a nationwide population-based survey (≥65 years) in Taiwan. The 5-dimension EuroQoL questionnaire (EQ-5D) was completed by 10 013 participants. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518813548DOI Listing
February 2019
2 Reads

Prevalence and Causes of Cognitive Impairment and Dementia in a Population-Based Cohort From Northern Portugal.

Am J Alzheimers Dis Other Demen 2019 Feb 4;34(1):49-56. Epub 2018 Dec 4.

1 EPIUnit-Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal.

Background:: Vascular disease may play an important role in the epidemiology of dementia in countries with high stroke incidence, such as Portugal.

Objective:: To assess the prevalence and etiology of cognitive impairment in a population-based cohort from Portugal.

Methods:: Individuals ≥55 years (n = 730) from the EPIPorto cohort were assessed using the Mini-Mental State Examination and the Montreal Cognitive Assessment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518813550DOI Listing
February 2019
1 Read

Identifying Brain Connectivity Using Network-Based Statistics in Amnestic Mild Cognitive Impairment Stratified by β-Amyloid Positivity.

Am J Alzheimers Dis Other Demen 2018 Nov 29:1533317518813556. Epub 2018 Nov 29.

3 Department of Neurology, Ulsan University College of Medicine, Asan Medical Center, Seoul, Korea.

Background:: The aim of this study was to identify white matter structural networks of amnestic mild cognitive impairment (aMCI) dichotomized by β amyloid (Aβ) status and compare them using network-based statistics (NBS).

Methods:: Patients underwent whole-brain diffusion-weighted magnetic resonance imaging, detailed neuropsychological test and [F]-Florbetaben amyloid positron emission tomography. We performed the NBS analysis to compare the whole-brain white matter structural networks extracted from diffusion tensor images. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518813556DOI Listing
November 2018
10 Reads

Relationship Continuity/Discontinuity-A Framework for Investigating the Role of Relationships in the Experience of Living With Dementia.

Authors:
Gerard A Riley

Am J Alzheimers Dis Other Demen 2019 May 19;34(3):145-147. Epub 2018 Nov 19.

1 University of Birmingham, Birmingham, United Kingdom.

A recent paper (Riley, Evans and Oyebode, 2018) reported that a sense of discontinuity in carers' experience of their spousal relationship with a person with dementia is associated with a greater sense of burden and fewer rewards from the caregiving role. This commentary sets the paper in context by providing a brief overview of research relating to relationship continuity/discontinuity. Factors that may explain why some carers experience continuity but others discontinuity are reviewed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518813557DOI Listing
May 2019
5 Reads

Delirium and Antipsychotic Medications at Hospital Intake: Screening to Decrease Likelihood of Aggression in Inpatient Settings Among Unknown Patients With Dementia.

Am J Alzheimers Dis Other Demen 2018 Nov 1:1533317518809345. Epub 2018 Nov 1.

3 UCF College of Medicine, University of Central Florida, Orlando, FL, USA.

For individuals with dementia, disorientation and both external and internal stimuli may trigger behaviors that are difficult to manage or dangerous to health-care providers. Identification of correlational risk factors to aggressive behavior in patients who are unknown to the hospital can allow providers to adapt patient care quickly. Records for patients aged 60+ who spent at least 24 hours at the hospital other than in the psychiatric unit were used (N = 14 080). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518809345DOI Listing
November 2018
3 Reads

Cognitive Stimulating Play Intervention for Dementia: A Feasibility Randomized Controlled Trial.

Am J Alzheimers Dis Other Demen 2019 Feb 28;34(1):63-71. Epub 2018 Oct 28.

4 Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.

This study investigates the feasibility and the preliminary efficacy of a Cognitive Stimulating Play Intervention on cognitive functions. Thirty older people with early to moderate dementia were recruited from 2 day-care centers, which were randomized into intervention and control groups. The recruitment, attendance, completion rates, and the interview with staff showed that the intervention was feasible. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1533317518808036
Publisher Site
http://dx.doi.org/10.1177/1533317518808036DOI Listing
February 2019
1 Read

Using Video Feedback at Home in Dementia Care: A Feasibility Study.

Am J Alzheimers Dis Other Demen 2019 May 23;34(3):153-162. Epub 2018 Oct 23.

1 Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen, the Netherlands.

Video feedback at home (VFH) aims to improve the well-being of informal caregivers and persons with dementia by training the caregiver to communicate successfully. This feasibility study had 2 aims: (1) to investigate possible effects regarding VFH, caregiver self-efficacy and the burden experienced, and the frequency of challenging behavior in persons with dementia, and (2) to perform a process evaluation of barriers and facilitators regarding the use of VFH. The respondents were caregivers of home-dwelling persons with dementia participating in VHF (N = 10), a group of caregivers who declined participating in VFH (N = 18), stakeholders (N = 6), and field experts (N = 55). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518808021DOI Listing
May 2019
15 Reads

Musical Features and Affective Responses to Personalized Playlists in People With Probable Dementia.

Am J Alzheimers Dis Other Demen 2018 Oct 21:1533317518808011. Epub 2018 Oct 21.

3 Translational Health Research Institute, Western Sydney University, Sydney, Australia.

Objectives: Personalized music playlists are increasingly being utilized in aged care settings. This study aims to investigate how musical features influence the affective response to music of people with probable dementia.

Methods: A factorial experiment (2 × 2 × 3) was conducted to investigate the influence of tempo (fast, slow), mode (major, minor), and lyrics (none, negative, positive). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518808011DOI Listing
October 2018
7 Reads

Reliability and Validity of Rowland Universal Dementia Assessment Scale in Turkish Population.

Am J Alzheimers Dis Other Demen 2019 Feb 17;34(1):34-40. Epub 2018 Oct 17.

1 Department of Internal Medicine, Istanbul University Cerrahpasa Medical Faculty, Geriatric Medicine, Istanbul, Turkey.

Background:: The aim is to validate Turkish version Rowland Universal Dementia Assessment Scale (RUDAS).

Methods:: One hundred forty patients (>65 years) were included. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition -V was used in all patients. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1533317518802449
Publisher Site
http://dx.doi.org/10.1177/1533317518802449DOI Listing
February 2019
18 Reads

Effects of Hand Exercise on Eating Action in Patients With Alzheimer's Disease.

Am J Alzheimers Dis Other Demen 2019 Feb 9;34(1):57-62. Epub 2018 Oct 9.

1 Fujian Medical University Affiliated Clinical Provincial Medical Institute, Fujian Provincial Hospital, Nursing School of Fujian Medical University, Fujian Province, China.

We aim to investigate whether a popular hand exercise could be used to improve the action of eating in patients with Alzheimer's disease (AD). A 6-month intervention was conducted in 60 patients with AD who live in a nursing home. They were divided into hand exercise and control groups. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518803722DOI Listing
February 2019
16 Reads

The Role of Gender in Shame, Hostility, and Aggression Experienced by Caregivers for Patients With Dementia.

Am J Alzheimers Dis Other Demen 2018 Oct 7:1533317518802458. Epub 2018 Oct 7.

1 Alzheimer Hellas, Thessaloniki, Greece.

The aim of this study was to investigate the differences between male and female caregivers for patients with dementia in the way they experience various psychosocial parameters such as shame, hostility, and aggression. The sample included 55 caregivers of patients with moderate and severe dementia, whereas the average age was 51 years. Female caregivers were found to experience significantly higher levels of external shame, measured by Other As Shamer scale, than male caregivers, t (53) = 2. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1533317518802458
Publisher Site
http://dx.doi.org/10.1177/1533317518802458DOI Listing
October 2018
18 Reads

Evaluating the Benefits of the TimeSlips Creative Storytelling Program for Persons With Varying Degrees of Dementia Severity.

Am J Alzheimers Dis Other Demen 2019 May 7;34(3):163-170. Epub 2018 Oct 7.

3 Department of Humanities, Penn State College of Medicine, Hershey, PA, USA.

Objectives: To evaluate the benefits of TimeSlips, a group creative storytelling intervention used in residential care settings, on quality of life (QOL), interactions with caregivers, and Mini-Mental State Examination (MMSE) scores for persons with varying degrees of dementia severity.

Design: A mixed-methods approach was used weekly over a 6-month period to measure QOL and resident-caregiver relationships.

Setting: A dementia care unit in Pennsylvania. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1533317518802427
Publisher Site
http://dx.doi.org/10.1177/1533317518802427DOI Listing
May 2019
13 Reads

The Effectiveness of Reality Orientation Therapy in the Treatment of Parkinson Disease Dementia.

Am J Alzheimers Dis Other Demen 2018 Oct 4:1533317518802461. Epub 2018 Oct 4.

2 Movement Disorders Unit, Neurology Service, Hospital de Clínicas-Federal University of Parana, Curitiba, Brazil.

Patients with Parkinson disease dementia (PDD) have deficits resulting mainly from frontostriatal dysfunction. The aim of this study was to assess the effectiveness of reality orientation therapy (ROT) combined with drug therapy (acetylcholinesterase inhibitors) in PDD treatment and compare it with that of drug therapy alone. Patients (n = 12) with a diagnosis of PDD were divided into 2 groups: group A-drug therapy and ROT; group B-drug therapy alone. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1533317518802461
Publisher Site
http://dx.doi.org/10.1177/1533317518802461DOI Listing
October 2018
5 Reads

Effect of Exercise on Behavioral Symptoms and Pain in Patients With Dementia Living in Nursing Homes.

Am J Alzheimers Dis Other Demen 2018 Oct 3:1533317518803773. Epub 2018 Oct 3.

1 Gérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse, Toulouse, France.

Objectives: Examine the effects of a 6-month exercise intervention on neuropsychiatric symptoms, pain, and medication consumption in older people with dementia (PWD) living in nursing homes (NH).

Methods: Ninety-one older PWD living in NH performed a 6-month structured exercise intervention (n = 44) or a social activity intervention (n = 47). Neuropsychiatric symptoms were measured by the neuropsychiatric inventory (NPI), pain was assessed using the Algoplus scale, and dementia-related drug prescriptions were obtained for all participants. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1533317518803773
Publisher Site
http://dx.doi.org/10.1177/1533317518803773DOI Listing
October 2018
3 Reads

The Cretan Aging Cohort: Cohort Description and Burden of Dementia and Mild Cognitive Impairment.

Am J Alzheimers Dis Other Demen 2019 Feb 27;34(1):23-33. Epub 2018 Sep 27.

2 Psychiatry Department, University of Crete, Medical School, Heraklion, Crete, Greece.

Our aim was to explore the burden of dementia in the Cretan Aging Cohort, comprised of 3140 persons aged ≥60 years (56.8% women, 5.8 ± 3. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518802414DOI Listing
February 2019
17 Reads

Evaluation of Cognitive Functions of Individuals Older Than 65 With Diagnosis of Diabetes.

Am J Alzheimers Dis Other Demen 2019 May 27;34(3):171-175. Epub 2018 Sep 27.

2 Department of Internal Medicine Nursing, Faculty of Health Science, Mehmet Akif Ersoy University, Burdur, Turkey.

This study was conducted in order to examine the level of cognitive function of individuals ≥65 years of age with diabetes. The cross-sectional descriptive design was used. The research was carried out in the diabetes polyclinic of a university hospital between June 2016 and January 2018. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1533317518802453
Publisher Site
http://dx.doi.org/10.1177/1533317518802453DOI Listing
May 2019
16 Reads

Dementia-Related Results of "Costs of Medication in Older Patients: Before and After Comprehensive Geriatric Assessment".

Am J Alzheimers Dis Other Demen 2018 12 24;33(8):497-499. Epub 2018 Sep 24.

2 Department of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.

Changes in the pharmacokinetics and pharmacodynamics of drugs in the presence of certain comorbidities and geriatric syndromes and reduced tolerability of potential drug side effects due to physiological changes with aging lead to difficulties in planning treatments in elderly adults, especially patients with dementia. The Comprehensive Geriatric Assessment has an important role in assessing polypharmacy and optimizing potentially inappropriate medications and potentially prescribing omissions in these patients. For this reason, we intend to reexamine our new study titled " Costs of medication in older patients: before and after comprehensive geriatric assessment," because most of these results are also very important for dementia practice. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518802434DOI Listing
December 2018
4 Reads

Comparison of Blood Lead Levels in Patients With Alzheimer's Disease and Healthy People.

Am J Alzheimers Dis Other Demen 2018 12 22;33(8):541-547. Epub 2018 Aug 22.

1 Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran.

Background: It is argued that breakdown of β-amyloid in the brain causes deposition of senescent plaques and therefore Alzheimer's disease (AD). One of the influential factors for increasing level of this protein is exposure to lead. Our aim was to compare blood lead levels (BLLs) between patients with AD and healthy controls. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518794032DOI Listing
December 2018
17 Reads

Apathy in Preclinical Alzheimer's Disease: Psychometric Validation of the Apathy Evaluation Scale.

Am J Alzheimers Dis Other Demen 2019 Feb 14;34(1):16-22. Epub 2018 Aug 14.

2 Geriatric Research, Education and Clinical Center, W. S. Middleton Memorial Veterans Hospital, Madison, WI, USA.

Objectives:: The purpose of the present study was to validate the Apathy Evaluation Scale, self-rated version (AES-S), and assess the severity of apathy in a cognitively healthy middle-aged cohort at risk for Alzheimer's disease (AD).

Method:: Three hundred and sixteen middle-aged adults were selected to represent a subset of the Wisconsin Alzheimer's Disease Research Center Clinical Core: the Investigating Memory in People At-risk, Causes and Treatments cohort.

Results:: An exploratory factor analysis (EFA) with varimax rotation identified 3 subscales: apathy, disinterest, and social withdrawal factors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518794020DOI Listing
February 2019
17 Reads

Trends in Hospital Morbidity From Alzheimer's Disease in the European Union, 2000 to 2014.

Am J Alzheimers Dis Other Demen 2018 11 1;33(7):440-449. Epub 2018 Aug 1.

1 Department of Health Sciences, Public University of Navarra, Pamplona, Navarra, Spain.

Background: Alzheimer's disease (AD) has become a concerning public health issue. We aimed to analyze the trends of hospital morbidity from AD in the European Union (EU) in the period 2000 to 2014.

Methods: Data from hospital discharges of men and women over 50 years old hospitalized due to AD in the EU were extracted from Eurostat database. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518787270DOI Listing
November 2018
2 Reads

Mild Cognitive Impairment in Clinical Practice: A Review Article.

Am J Alzheimers Dis Other Demen 2018 12 1;33(8):500-507. Epub 2018 Aug 1.

2 Division of Geriatric Medicine, Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

The spectrum of cognitive decline in the elderly ranges from what can be classified as normal cognitive decline with aging to subjective cognitive impairment to mild cognitive impairment (MCI) to dementia. This article reviewed the up-to-date evidence of MCI including the diagnostic criteria of MCI due to Alzheimer's disease, vascular cognitive impairment and MCI due to Parkinson disease, management and preventive intervention of MCI. There are various etiologies of MCI, and a large number of studies have been conducted to ascertain the practical modalities of preserving cognition in predementia stages. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518791401DOI Listing
December 2018
10 Reads

Women's Pregnancy Life History and Alzheimer's Risk: Can Immunoregulation Explain the Link?

Am J Alzheimers Dis Other Demen 2018 12 30;33(8):516-526. Epub 2018 Jul 30.

5 Department of Psychology, Chapman University, Orange, CA, USA.

Background: Pregnancy is associated with improvement in immunoregulation that persists into the geriatric phase. Impaired immunoregulation is implicated in Alzheimer's disease (AD) pathogenesis. Hence, we investigate the relationship between pregnancy and AD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518786447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442681PMC
December 2018

Classification of Alzheimer's Disease Stages: An Approach Using PCA-Based Algorithm.

Am J Alzheimers Dis Other Demen 2018 11 29;33(7):433-439. Epub 2018 Jul 29.

1 Department of Statistics, University of Gujrat, Gujrat, Pakistan.

Early diagnosis of Alzheimer's disease (AD) allows individuals and their health managers to manage healthier medication. We proposed an approach for classification of AD stages, with respect to principal component analysis (PCA)-based algorithm. The PCA has been extensively applied as the most auspicious face-recognition algorithm. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518790038DOI Listing
November 2018
17 Reads

Neurochemical Aspects of Alzheimer's Disease and Movement Disturbances: A Theory of β-Amyloid and τ-Protein.

Am J Alzheimers Dis Other Demen 2018 12 25;33(8):535-540. Epub 2018 Jul 25.

1 Department of Acute Geriatric Medicine & Rehabilitation, St Willibrord-Spital Emmerich-Rees, Emmerich, Germany.

The pathologic and molecular substrate of people diagnosed with cognitive deficits and movement disturbance may not occur exclusively in the context of a brain region, but it may be expressed in another part of body such as muscle. A large body of research has demonstrated that slow motor performance is associated with cognitive impairment in elderly people. The interdependence between motor dysfunction and cognition decline is still not fully understood. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518790631DOI Listing
December 2018

Reduced Lexical Access to Verbs in Individuals With Subjective Cognitive Decline.

Am J Alzheimers Dis Other Demen 2019 Feb 24;34(1):5-15. Epub 2018 Jul 24.

1 Département de réadaptation, Faculté de médecine, Université Laval, Quebec City, Quebec, Canada.

The detection of cognitive impairment in individuals with subjective cognitive decline (SCD) may improve detection of the emergence of Alzheimer's disease (AD) pathology. This detection is challenging, however, given the lack of sensitive assessment tools. The main objective of this study was to determine the potential contribution of word production tasks to the detection of cognitive impairment in SCD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518790541DOI Listing
February 2019
1 Read

Informant Personality Is Associated With Ratings of Memory Problems in Older Adults.

Am J Alzheimers Dis Other Demen 2018 11 24;33(7):479-489. Epub 2018 Jul 24.

1 Department of Psychology, University of Westminster, London, United Kingdom.

Memory complaints are a key diagnostic criterion for dementia and mild cognitive impairment. Rating scales can be used to capture information about individuals' memory problems from informants such as family members. However, problems with scale reliability suggest that individual differences influence the ratings informants provide. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518790540DOI Listing
November 2018
3 Reads

Reducing Burden for Caregivers of Older Adults With Mild Cognitive Impairment: A Systematic Review.

Am J Alzheimers Dis Other Demen 2018 11 24;33(7):401-414. Epub 2018 Jul 24.

1 CERVO Brain Research Centre, Quebec, Canada.

Background/rationale: This systematic review aims to evaluate the efficacy of the nonpharmacological interventions reducing burden, psychological symptoms, and improving quality of life of caregivers of individuals with mild cognitive impairment (MCI).

Method: Databases reviewed included Medline, Cochrane Library, Embase, PsycNet, AgeLine, and ProQuest Dissertations and Theses. Studies using an experimental/quasi-experimental design including nonpharmacological intervention were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317518788151DOI Listing
November 2018
21 Reads