371,826 results match your criteria American Politics Research[Journal]


Electronic structure benchmark calculations of CO fixing elementary chemical steps in RuBisCO using the projector-based embedding approach.

J Comput Chem 2020 Jul 8. Epub 2020 Jul 8.

Departamento de Físico-Química, Facultad de Ciencias Químicas, Universidad de Concepción, Concepción, Chile.

Ribulose 1,5-bisphosphate carboxylase-oxygenase (RuBisCO) is the main enzyme involved in atmospheric carbon dioxide (CO ) fixation in the biosphere. This enzyme catalyzes a set of five chemical steps that take place in the same active-site within magnesium (II) coordination sphere. Here, a set of electronic structure benchmark calculations have been carried out on a reaction path proposed by Gready et al. Read More

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http://dx.doi.org/10.1002/jcc.26380DOI Listing

COVID-19, obesity and undernutrition: A major challenge for Latin American countries.

Obesity (Silver Spring) 2020 Jul 8. Epub 2020 Jul 8.

Centro de Investigación en Nutrición y Salud, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, México.

In March of 2020, the World Health Organization declared the SARS-Cov2 2019 (COVID-19) outbreak a global pandemic after documenting community scale transmission in every region, including Latin America. The risk factors associated with severity of disease include older age, diabetes, hypertension, cardiovascular and lung diseases, and immune suppression. Additional evidence strongly suggests that obesity is also a risk factor for severe forms of COVID-19 disease, while other types of malnutrition increase the risk of hospitalization from influenza-like diseases, regardless of the causative agent of the illness (1). Read More

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http://dx.doi.org/10.1002/oby.22961DOI Listing

Characterization of pharmaceuticals, personal care products, and polybrominated diphenyl ethers in lake sturgeon serum and gametes.

Environ Pollut 2020 Jun 26;266(Pt 1):115051. Epub 2020 Jun 26.

U.S. Fish and Wildlife Service, 5600 American Blvd. West, Suite 990, Bloomington, MN, 55437, USA. Electronic address:

Recent research suggests contaminants of emerging concern (CECs) are widespread and environmentally relevant concentrations can impact fishes. However, little is known about impacts of CECs to long-lived or rare species. The objective of this study was to characterize CEC concentrations in lake sturgeon (Acipenser fulvescens) serum and gametes. Read More

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http://dx.doi.org/10.1016/j.envpol.2020.115051DOI Listing

Alcohol Use Disorder Is Bad for Broken Ribs: A Nationwide Analysis of 19,638 Patients With Rib Fractures.

J Surg Res 2020 Jul 5;255:556-564. Epub 2020 Jul 5.

Division of Trauma, Critical Care, Emergency Surgery, and Burns, Department of Surgery, College of Medicine, University of Arizona, Tucson, Arizona. Electronic address:

Background: Alcohol use disorder (AUD) has deleterious effects on many organ systems. The aim of our study was to assess the impact of AUD on outcomes in patients with rib fractures. We hypothesized that AUD is associated with increased risk adverse outcomes. Read More

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http://dx.doi.org/10.1016/j.jss.2020.05.053DOI Listing

Impact of preemptive therapy for Cytomegalovirus on hospitalizations and cost after Hematopoietic Stem Cell Transplantation.

Biol Blood Marrow Transplant 2020 Jul 5. Epub 2020 Jul 5.

Memorial Sloan Kettering Cancer Center, Infectious Disease Service, New York, NY, United States; Weill Cornell Medical College, Cornell University, New York, NY, United States. Electronic address:

Background: CMV viremia occurs in 40%-80% of CMV seropositive (R+) allogeneic hematopoietic stem cell (HCT) recipients. The preemptive therapy (PET) strategy has reduced the risk of CMV end-organ disease (EOD) and associated mortality but may lead to substantial healthcare resource utilization (HCRU) and cost. Real-world data on the economic impact of PET is relevant for the evaluation of alternative strategies for CMV management. Read More

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http://dx.doi.org/10.1016/j.bbmt.2020.06.025DOI Listing

Surgical management of the aorta in BAV patients.

Prog Cardiovasc Dis 2020 Jul 5. Epub 2020 Jul 5.

University Clinic of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany. Electronic address:

Patients with a bicuspid aortic valve (BAV) frequently develop aneurysms of the aortic root and tubular ascending aorta. Aneurysms of the aortic arch, in the absence of concomitant aortopathies, are much less common. According to the 2018 American Association of Thoracic Surgery consensus guidelines on BAV-related aortopathy, prophylactic surgical aortic repair / replacement is recommended starting at a maximum aortic diameter of 50 mm in patients with risk factors. Read More

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http://dx.doi.org/10.1016/j.pcad.2020.06.013DOI Listing

Long-term outcome of postmenopausal women with proliferative endometrium on endometrial sampling.

Am J Obstet Gynecol 2020 Jul 5. Epub 2020 Jul 5.

Introduction: Proliferative endometrium has been reported in 15% of endometrial biopsies of women 50 and older. In contrary to endometrial hyperplasia, proliferative endometrium has not been associated with risk of endometrial cancer. We sought to report on the long-term outcome of postmenopausal women diagnosed with proliferative endometrium. Read More

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http://dx.doi.org/10.1016/j.ajog.2020.06.045DOI Listing

Characterization of Exome Variants and Their Metabolic Impact in 6,716 American Indians from the Southwest US.

Am J Hum Genet 2020 Jul 2. Epub 2020 Jul 2.

Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA. Electronic address:

Applying exome sequencing to populations with unique genetic architecture has the potential to reveal novel genes and variants associated with traits and diseases. We sequenced and analyzed the exomes of 6,716 individuals from a Southwestern American Indian (SWAI) population with well-characterized metabolic traits. We found that the SWAI population has distinct allelic architecture compared to populations of European and East Asian ancestry, and there were many predicted loss-of-function (pLOF) and nonsynonymous variants that were highly enriched or private in the SWAI population. Read More

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http://dx.doi.org/10.1016/j.ajhg.2020.06.009DOI Listing

How Much May COVID-19 School Closures Increase Childhood Obesity?

Authors:
Joseph Workman

Obesity (Silver Spring) 2020 Jul 8. Epub 2020 Jul 8.

University of Missouri, Kansas City, United States.

In a recent paper entitled, "COVID-19 Related School Closings and Risk of Weight Gain Among Children" Rundle et al. (2020) proposed the COVID-19 pandemic may increase obesity among American children because the pandemic, "will likely double out-of-school time this year for many children in the United States and will exacerbate the risk factors for weight gain associated with summer recess" (pg. 1). Read More

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http://dx.doi.org/10.1002/oby.22960DOI Listing

Antihypertensive Treatment in Elderly Frail Patients: Evidence From a Large Italian Database.

Hypertension 2020 Aug 8;76(2):330-332. Epub 2020 Jul 8.

From the Department of Medicine, University of South Carolina School of Medicine Greenville; and Improving Health Outcomes, American Medical Association, Greenville, SC.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.14786DOI Listing

MARCKS-Like Protein-1(MLP-1) regulates ENaC Activity in Renal Distal Convoluted Tubule Cells.

Am J Physiol Cell Physiol 2020 Jul 8. Epub 2020 Jul 8.

Division of Nephrology, Department of Medicine, Emory University, Atlanta, GA.

ENaC gating is regulated by phosphatidylinositol 4,5-bisphosphate (PIP). The PIP-dependent regulation of ENaC is mediated by the myristoylated alanine-rich protein kinase C substrate-like protein-1 (MLP-1). MLP-1 binds to PIP at the plasma membrane. Read More

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http://dx.doi.org/10.1152/ajpcell.00218.2020DOI Listing

Bringing the Cellular Clock into Understanding Lung Disease: It's Time, Period!

Am J Physiol Lung Cell Mol Physiol 2020 Jul 8. Epub 2020 Jul 8.

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, United States.

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http://dx.doi.org/10.1152/ajplung.00320.2020DOI Listing

Triage of patients with venous and lymphatic diseases during the COVID-19 pandemic - The Venous and Lymphatic Triage and Acuity Scale (VELTAS): A consensus document of the International Union of Phlebology (UIP), Australasian College of Phlebology (ACP), American Vein and Lymphatic Society (AVLS), American Venous Forum (AVF), European College of Phlebology (ECoP), European Venous Forum (EVF), Interventional Radiology Society of Australasia (IRSA), Latin American Venous Forum, Pan-American Society of Phlebology and Lymphology and the Venous Association of India (VAI) This consensus document has been co-published in [DOI: 10.1177/0268355520930884 ] and [DOI: 10.1016/j.jvsv.2020.05.002 ]. The publications are identical except for minor stylistic and spelling differences in keeping with each journal's style. The contribution has been published under a Attribution-Non Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0), ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).

Phlebology 2020 Jul 8:268355520930884. Epub 2020 Jul 8.

European College of Phlebology (ECoP).

The coronavirus disease 2019 (COVID-19) global pandemic has resulted in diversion of healthcare resources to the management of patients infected with SARS-CoV-2 virus. Elective interventions and surgical procedures in most countries have been postponed and operating room resources have been diverted to manage the pandemic. The Venous and Lymphatic Triage and Acuity Scale was developed to provide an international standard to rationalise and harmonise the management of patients with venous and lymphatic disorders or vascular anomalies. Read More

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http://dx.doi.org/10.1177/0268355520930884DOI Listing

Pulsar Timing Array Constraints on Primordial Black Holes with NANOGrav 11-Year Dataset.

Phys Rev Lett 2020 Jun;124(25):251101

CAS Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 100190, China.

The detection of binary black hole coalescences by LIGO and Virgo has aroused the interest in primordial black holes (PBHs), because they could be both the progenitors of these black holes and a compelling candidate of dark matter (DM). PBHs are formed soon after the enhanced scalar perturbations reenter horizon during the radiation dominated era, which would inevitably induce gravitational waves as well. Searching for such scalar induced gravitational waves (SIGWs) provides an elegant way to probe PBHs. Read More

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http://dx.doi.org/10.1103/PhysRevLett.124.251101DOI Listing

Candidate Electromagnetic Counterpart to the Binary Black Hole Merger Gravitational-Wave Event S190521g.

Phys Rev Lett 2020 Jun;124(25):251102

Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA.

We report the first plausible optical electromagnetic counterpart to a (candidate) binary black hole merger. Detected by the Zwicky Transient Facility, the electromagnetic flare is consistent with expectations for a kicked binary black hole merger in the accretion disk of an active galactic nucleus [B. McKernan, K. Read More

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http://dx.doi.org/10.1103/PhysRevLett.124.251102DOI Listing

A path to improve colorectal cancer screening outcomes: faculty roundtable evaluation of cost-effectiveness and utility.

Am J Manag Care 2020 Jun;26(6 Suppl):S123-S143

University of Michigan, 2800 Plymouth Rd, Bldg 16, Floor 4, 016-400S-25, Ann Arbor, MI 48109-2800. Email:

The American Journal of Managed Care® and Exact Sciences Corporation hosted a roundtable meeting to discuss the impact of colorectal cancer (CRC) screening modalities on improving patient outcomes. The roundtable participants were a diverse panel of experts, including primary care, gastroenterology, and oncology providers; experts in health outcomes research and health policy; and managed care executives with commercial and public payer experience. Participants discussed CRC prevention and treatment strategies, screening modalities and adherence, molecular diagnostics, patient navigation, evaluation of large data sets, managed care, outcomes research, quality improvement, and reimbursement policies. Read More

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http://dx.doi.org/10.37765/ajmc.2020.43732DOI Listing

A novel mutation in PDE6B in Spanish Water Dogs with early-onset progressive retinal atrophy.

Vet Ophthalmol 2020 Jul 8. Epub 2020 Jul 8.

Department of Small Animal Clinical Sciences, Veterinary Medical Center, Michigan State University, East Lansing, MI, USA.

Objective: To identify the underlying mutation in a recently identified early-onset progressive retinal atrophy (PRA) in the Spanish Water Dog (SWD) breed.

Animal Studied: Eighteen SWDs were used in this study. Six SWDs diagnosed with PRA and 12 phenotypically normal SWDs. Read More

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http://dx.doi.org/10.1111/vop.12792DOI Listing

Golden retriever pigmentary uveitis: Challenges of diagnosis and treatment.

Vet Ophthalmol 2020 Jul 8. Epub 2020 Jul 8.

Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.

Pigmentary uveitis (PU), also known as Golden Retriever Pigmentary Uveitis (GRPU), is a common ocular condition of Golden Retrievers that has severe, vision-threatening ocular complications and can require surgical intervention. In order to ensure consistency in the diagnosis of GRPU between examiners, a specified set of diagnostic criteria must be applied. This is critical to ensure owners, breeders, and veterinary ophthalmologists maintain confidence in the ocular certification process. Read More

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http://dx.doi.org/10.1111/vop.12796DOI Listing

Idiopathic Right Ventricular Arrhythmias With Changes in the QRS Morphology After Ablation.

J Cardiovasc Electrophysiol 2020 Jul 8. Epub 2020 Jul 8.

Division of Cardiology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

Idiopathic ventricular arrhythmias (VA) is defined as premature ventricular complexes (PVCs) or ventricular tachycardias (VT) that occur in the absence of structural heart disease. Endocardial radiofrequency (RF) ablation is often curative for idiopathic VA. The success of the procedure depends on the ability to localize the abnormal foci accurately. Read More

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http://dx.doi.org/10.1111/jce.14656DOI Listing

Association Between Federal Value-Based Incentive Programs and Health Care-Associated Infection Rates in Safety-Net and Non-Safety-Net Hospitals.

JAMA Netw Open 2020 Jul 1;3(7):e209700. Epub 2020 Jul 1.

Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California.

Importance: In the US, federal value-based incentive programs are more likely to penalize safety-net institutions than non-safety-net institutions. Whether these programs differentially change the rates of targeted health care-associated infections in safety-net vs non-safety-net hospitals is unknown.

Objective: To assess the association of Hospital-Acquired Condition Reduction Program (HACRP) and Hospital Value-Based Purchasing (HVBP) implementation with changes in rates of targeted health care-associated infections and disparities in rates among safety-net and non-safety-net hospitals. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2020.9700DOI Listing

The effects of intensive speech treatment on intelligibility in Parkinson's disease: A randomised controlled trial.

EClinicalMedicine 2020 Jul 28;24:100429. Epub 2020 Jun 28.

Department of Biobehavioral Sciences, Teachers College, Columbia University, New York, NY, United States.

Background: More than 6,000,000 individuals worldwide are diagnosed with Parkinson's disease (PD). Nearly 90% develop speech signs that may substantially impair their speech intelligibility, resulting in losses in their communication and quality of life. Benefits of intensive speech treatment have been documented for a range of speech signs. Read More

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http://dx.doi.org/10.1016/j.eclinm.2020.100429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327886PMC

A Randomized Comparative Trial to Evaluate a PICU Navigator-Based Parent Support Intervention.

Pediatr Crit Care Med 2020 Jun 22. Epub 2020 Jun 22.

Program in Ethics and Decision Making in Critical Illness, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Objectives: Communication breakdowns in PICUs contribute to inadequate parent support and poor post-PICU parent outcomes. No interventions supporting communication have demonstrated improvements in parental satisfaction or psychologic morbidity. We compared parent-reported outcomes from parents receiving a navigator-based parent support intervention (PICU Supports) with those from parents receiving an informational brochure. Read More

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http://dx.doi.org/10.1097/PCC.0000000000002378DOI Listing

Clinical Features of Critical Coronavirus Disease 2019 in Children.

Pediatr Crit Care Med 2020 Jul 2. Epub 2020 Jul 2.

The Ryan White Center for Pediatric Infectious Disease and Global Health, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.

Objectives: We sought to describe the presentation, course, and outcomes of hospitalized pediatric coronavirus disease 2019 patients, with detailed description of those requiring mechanical ventilation, and comparisons between critically ill and noncritical hospitalized pediatric patients.

Design: Observational cohort study.

Setting: Riley Hospital for Children at Indiana University Health in Indianapolis in the early weeks of the coronavirus disease 2019 pandemic. Read More

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http://dx.doi.org/10.1097/PCC.0000000000002511DOI Listing

Etiology of Sudden Cardiac Arrest and Death in US Competitive Athletes: A 2-Year Prospective Surveillance Study.

Clin J Sport Med 2020 Jul;30(4):305-314

Department of Family Medicine, Center for Sports Cardiology, University of Washington, Seattle, Washington.

Objective: To determine the etiology of sudden cardiac arrest and death (SCA/D) in competitive athletes through a prospective national surveillance program.

Design: Sudden cardiac arrest and death cases in middle school, high school, college, and professional athletes were identified from July 2014 to June 2016 through traditional and social media searches, reporting to the National Center for Catastrophic Sports Injury Research, communication with state and national high school associations, review of the Parent Heart Watch database, and search of student-athlete deaths on the NCAA Resolutions List. Autopsy reports and medical records were reviewed by a multidisciplinary panel to determine the underlying cause. Read More

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http://dx.doi.org/10.1097/JSM.0000000000000598DOI Listing

Outcomes and Predictors of Wound Healing among Patients with Complex Diabetic Foot Wounds Treated with a Dermal Regeneration Template (Integra®).

Plast Reconstr Surg 2020 Jun 29. Epub 2020 Jun 29.

Diabetic Foot and Wound Service, The Johns Hopkins Hospital, Baltimore, MD.

Background: The utility of dermal regeneration templates for treating high-risk diabetic foot wounds (DFW) is unclear. We report wound healing and major amputation outcomes among a cohort of diabetic patients with complex DFW treated in a multidisciplinary setting.

Methods: All patients with complex DFW treated with a dermal regeneration template (03/2013-2/2019) were captured in a prospective institutional database. Read More

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http://dx.doi.org/10.1097/PRS.0000000000007166DOI Listing

Big Data in Transplantation Practice - the Devil Is in the Detail - Fontan-associated Liver Disease.

Transplantation 2020 Jul 2. Epub 2020 Jul 2.

Liver Transplant Center, Children's Hospital-Los Angeles, Los Angeles, CA.

Background: As a result of the Fontan procedure, the prognosis of congenital single-ventricle heart disease has improved, with many affected children surviving into adulthood. However, the unanticipated consequences of chronic exposure to Fontan hemodynamics has revealed a new set of secondary noncardiac complications. Fontan-associated liver disease (FALD) is characterized by progressive hepatic fibrosis in nearly all patients post-Fontan, with the potential to develop cirrhosis, hepatocellular carcinoma, and the need for liver transplantation. Read More

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http://dx.doi.org/10.1097/TP.0000000000003308DOI Listing

Risk Factors for Intraoperative Hypoglycemia in Children: A Multicenter Retrospective Cohort Study.

Anesth Analg 2020 Jun 25. Epub 2020 Jun 25.

From the Department of Anesthesiology, University of Michigan Health System, Ann Arbor, Michigan.

Background: Intraoperative hypoglycemia can result in devastating neurologic injury if not promptly diagnosed and treated. Few studies have defined risk factors for intraoperative hypoglycemia. The authors sought to characterize children with intraoperative hypoglycemia and determine independent risk factors in a multicenter cohort. Read More

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http://dx.doi.org/10.1213/ANE.0000000000004979DOI Listing

Comparison of Pupillometry With Surgical Pleth Index Monitoring on Perioperative Opioid Consumption and Nociception During Propofol-Remifentanil Anesthesia: A Prospective Randomized Controlled Trial.

Anesth Analg 2020 Jul 2. Epub 2020 Jul 2.

Department of Anesthesiology and Pain Medicine, Hanyang University Medical Center, College of Medicine, Hanyang University, Seoul, Republic of Korea.

Background: Intraoperative monitoring with pupillometry has shown promising results for nociception/antinociception balance monitoring. However, its benefits in clinical practice remain unproven. The aim of this study was to evaluate the efficacy of intraoperative pupillometry monitoring on intraoperative opioid consumption and postoperative pain compared to surgical pleth index (SPI), another widely investigated monitoring. Read More

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http://dx.doi.org/10.1213/ANE.0000000000004958DOI Listing

Correlates of the Abnormal Involuntary Movement Scale in Veterans With Tardive Dyskinesia.

J Clin Psychopharmacol 2020 Jul/Aug;40(4):373-380

From the Behavioral Health Service, Corporal Michael J. Crescenz VA Medical Center.

Purpose/background: To add to limited evidence on the Abnormal Involuntary Movement Scale (AIMS) as a measure of tardive dyskinesia (TD) in clinical practice settings, the characteristics and correlates of AIMS scores were assessed.

Methods/procedures: Veterans with schizophrenia/schizoaffective, bipolar, or major depressive disorders receiving antipsychotics and at least 1 AIMS score during October 1, 2014, to September 30, 2015, were identified. Tardive dyskinesia was determined by the International Classification of Diseases, Ninth Revision, Clinical Modification, codes. Read More

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http://dx.doi.org/10.1097/JCP.0000000000001229DOI Listing

Focusing on Vulnerable Populations During COVID-19.

Acad Med 2020 Jul 2. Epub 2020 Jul 2.

Assistant professor, Department of Surgery, Baylor College of Medicine, Houston, Texas; email: Assistant clinical professor, Department of Family Medicine, University of California, San Francisco, San Francisco, California. Internist, geriatrician, and former Chief Medical Officer, American Hospital Association, Chicago, Illinois. Chief, Division of Surgical Oncology, and Edward & Freda Green Professor in Surgical Oncology, Department of Surgery, LSU-Health Sciences Center-Shreveport, Shreveport, Louisiana. Associate chief medical officer, People's Community Clinic, Austin, Texas. Medical student, Baylor College of Medicine, Houston, Texas. Medical director of population care and value, Department of Internal Medicine, University of California, Davis, Sacramento, California. Assistant professor of pediatrics, population health, and public policy, Department of Pediatrics, The University of Texas at Austin, Austin, Texas. Associate professor of pediatrics, Department of Pediatrics, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota. Director, Farley Health Policy Center, University of Colorado Anschutz Medical Campus, Aurora, Colorado. Clinical assistant professor of pediatrics, The George Washington University School of Medicine and Health Sciences, and Division of Emergency Medicine, Children's National Hospital, Washington, DC. Assistant clinical professor, Department of Anesthesiology, University of Southern California, Los Angeles, California. President, House Medicine, Los Angeles, California. Clinical assistant professor of pediatrics, The George Washington University School of Medicine and Health Sciences, and Division of Emergency Medicine, Children's National Hospital, Washington, DC. Director, Emergency General Surgery, Johns Hopkins Hospital, Baltimore, Maryland. Chair, Department of Population Science and Policy, and assistant professor of pediatrics, medical humanities, and law, Southern Illinois University School of Medicine, Springfield, Illinois. Assistant health director, Grady Primary Care Center, and assistant professor, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia. Program director, Endocrinology, Diabetes, and Metabolism Fellowship, University of Arizona College of Medicine-Phoenix, and Phoenix Veterans Affairs Medical Center, Phoenix, Arizona.

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http://dx.doi.org/10.1097/ACM.0000000000003571DOI Listing

Coronavirus Disease among Persons with Sickle Cell Disease, United States, March 20-May 21, 2020.

Emerg Infect Dis 2020 Jul 8;26(10). Epub 2020 Jul 8.

Sickle cell disease (SCD) disproportionately affects Black or African American persons in the United States and can cause multisystem organ damage and reduced lifespan. Among 178 persons with SCD in the United States who were reported to an SCD-coronavirus disease case registry, 122 (69%) were hospitalized and 13 (7%) died. Read More

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http://dx.doi.org/10.3201/eid2610.202792DOI Listing

Racial/Ethnic Differences in Light of 100% Smoke-free State Laws: Evidence from Adults in the United States.

Popul Health Manag 2020 Jul 7. Epub 2020 Jul 7.

Faculty of Business, University of New Brunswick, Saint John, Canada.

This study estimates racial/ethnic differences in the association between 100% smoke-free state laws and smoking, as well as self-reported health, to facilitate policy aimed at reducing disparities. Data pertain to adults aged 18 years and older, obtained from the public-use Behavioral Risk Factor Surveillance System (2002-2014). The authors exploit variation in the timing of 100% smoke-free state laws using a difference-in-differences model. Read More

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http://dx.doi.org/10.1089/pop.2020.0048DOI Listing

The Feasibility and Acceptability of the Developing Real Incentives and Volition for Exercise (DRIVE) Program: A Pilot Study for Promoting Physical Activity in African American Women.

Health Promot Pract 2020 Jul 8:1524839920939572. Epub 2020 Jul 8.

University of Michigan, Ann Arbor, MI, USA.

. The purpose of the current article is to demonstrate how formative process evaluation was used in a pilot study to optimize the design and implementation of two motivationally targeted community-based physical activity (PA) interventions for inactive African American women. . Read More

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http://dx.doi.org/10.1177/1524839920939572DOI Listing

Matrix-Induced Autologous Chondrocyte Implantation (MACI) Grafting for Osteochondral Lesions of the Talus.

Foot Ankle Int 2020 Jul 8:1071100720935110. Epub 2020 Jul 8.

Melbourne Orthopaedic Group, Windsor, VIC, Australia.

Background: Matrix-induced autologous chondrocyte implantation (MACI) is an established treatment method for larger joints and has shown promising results in the ankle as well. We present a series of patients after ankle MACI with long-term follow-up of clinical and radiological outcomes.

Methods: We present the follow-up of 15 patients who underwent MACI grafting from August 2003 to February 2006. Read More

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http://dx.doi.org/10.1177/1071100720935110DOI Listing

Evaluation of an Innovative Informed Consent Support Program for Individuals Considering a Living Kidney Donation.

Nephrol Nurs J 2020 May-Jun;47(3):245-251

Nurse Clinician, Maisonneuve-Rosemont Hospital - Université de Montréal Affiliated Hospital Centre, Montréal, Québec, Canada.

Regulations require that consent be obtained before accepting a kidney donation, and respect for the competent adult requires the living donor to think, decide, and act freely, without any form of pressure or coercion. This article describes the results of a program, Les Compagnons de la Donation (Donation Companions), that attempts to meet these needs. A descriptive, non-experimental study was conducted to evaluate the degree of participant satisfaction and the program's influence on consent. Read More

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Multiple Dimensions and Correlates of Fatigue in Individuals on Hemodialysis.

Nephrol Nurs J 2020 May-Jun;47(3):215-251

Professor, College of Nursing, Wayne State University, Detroit, MI.

This study examined the severity, pattern, and correlates of fatigue among adults undergoing hemodialysis. Measures included the Piper Fatigue Scale (PFS-12), Patient-Reported Outcomes Measurement Information System (PROMIS) - Fatigue, Charlson Comorbidity Index, and Six-Minute Walk Test (6MWT). Patients were excluded if mobility or cardiovascular issues prevented conducting the 6MWT. Read More

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Modified Cornell electrocardiographic criteria in the assessment of left ventricular hypertrophy geometry of patients with essential hypertension.

J Clin Hypertens (Greenwich) 2020 Jul 8. Epub 2020 Jul 8.

Department of Echocardiography of The First Affiliated Hospital of Soochow University, Su Zhou, China.

To evaluate the value of modified Cornell electrocardiographic criteria in the assessment of left ventricular hypertrophy (LVH) for patients with essential hypertension. A total of 381 patients with essential hypertension diagnosed in our hospital were selected. Using the left ventricle (LV) geometric patterns classified by the American Society of Echocardiography (ASE), we examined the distribution of the modified Cornell criteria of Ravl + S (the deepest S wave in 12-lead ECG) in different geometric patterns and analyzed the correlation of modified Cornell criteria with changes in the LV geometric patterns using multiple linear regression analysis. Read More

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http://dx.doi.org/10.1111/jch.13919DOI Listing

Frailty in older patients undergoing emergency colorectal surgery: USA National Surgical Quality Improvement Program analysis.

Br J Surg 2020 Jul 8. Epub 2020 Jul 8.

Division of Colorectal Surgery.

Background: Frailty is associated with advancing age and may result in adverse postoperative outcomes. A suspected growing elderly population needing emergency colorectal surgery stimulated this study of the prevalence and impact of frailty.

Methods: Elderly patients (defined as aged at least 65 years by Medicare and the United States Census Bureau) who underwent emergency colorectal resection between 2012 and 2016 were identified from the American College of Surgeons National Surgical Quality Improvement Program population database. Read More

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http://dx.doi.org/10.1002/bjs.11770DOI Listing

Human papillomavirus vaccination 2020 guideline update: American Cancer Society guideline adaptation.

CA Cancer J Clin 2020 Jul 8. Epub 2020 Jul 8.

Louisiana State University School of Public Health, New Orleans, Louisiana.

The American Cancer Society (ACS) presents an adaptation of the current Advisory Committee on Immunization Practices recommendations for human papillomavirus (HPV) vaccination. The ACS recommends routine HPV vaccination between ages 9 and 12 years to achieve higher on-time vaccination rates, which will lead to increased numbers of cancers prevented. Health care providers are encouraged to start offering the HPV vaccine series at age 9 or 10 years. Read More

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http://dx.doi.org/10.3322/caac.21616DOI Listing

Evaluation of the Online-Presence of ABA-Verified Burn Centers.

J Burn Care Res 2020 Jul 8. Epub 2020 Jul 8.

Department of Surgery, University of Texas Medical Branch and Shriners Hospitals for Children-Galveston.

Currently, patients seek healthcare information online. An up-to-date online presence is vital for success among the competition amid hospitals. Hospital websites have become an important medium to communicate with patients, provide information about certain diseases/conditions, and advertise healthcare services. Read More

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http://dx.doi.org/10.1093/jbcr/irz204DOI Listing

The pharmacological interaction of compounds in ayahuasca: a systematic review.

Braz J Psychiatry 2020 Jul 3. Epub 2020 Jul 3.

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Ayahuasca is a South American psychoactive plant brew used as traditional medicine in spiritual and in cultural rituals. This is a review of the current understanding about the pharmacological mechanisms that may be interacting in ayahuasca. Searches were performed using PubMed, PsycINFO, and Web of Science databases and 16 papers were selected. Read More

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http://dx.doi.org/10.1590/1516-4446-2020-0884DOI Listing

The history of quality and safety of the surgical patient: from the initial standards to the present day.

Rev Col Bras Cir 2020 3;47:e20202650. Epub 2020 Jul 3.

Departamento de Cirurgia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

There are currently various concepts related to quality, which have been implemented by many hospitals and other healthcare institutions. The search for continuous improvement, the implementation of a quality culture and hospital accreditation have also been common, in these institutions. However, the history of hospital audits and accreditation is complex and full of dynamic concepts. Read More

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http://dx.doi.org/10.1590/0100-6991e-20202650DOI Listing

Position Statement: Cardiopulmonary Resuscitation of Patients with Confirmed or Suspected COVID-19 - 2020.

Arq Bras Cardiol 2020 Jun 3;114(6):1078-1087. Epub 2020 Jul 3.

Hospital Alberto Urquiza Wanderley, João Pessoa, PB, Brasil.

Care for patients with cardiac arrest in the context of the coronavirus disease 2019 (COVID-19) pandemic has several unique aspects that warrant particular attention. This joint position statement by the Brazilian Association of Emergency Medicine (ABRAMEDE), Brazilian Society of Cardiology (SBC), Brazilian Association of Intensive Care Medicine (AMIB), and Brazilian Society of Anesthesiology (SBA), all official societies representing the corresponding medical specialties affiliated with the Brazilian Medical Association (AMB), provides recommendations to guide health care workers in the current context of limited robust evidence, aiming to maximize the protection of staff and patients alike. It is essential that full aerosol precautions, which include wearing appropriate personal protective equipment, be followed during resuscitation. Read More

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http://dx.doi.org/10.36660/abc.20200548DOI Listing

Relationship between social indicators and food insecurity: a systematic review.

Rev Bras Epidemiol 2020 6;23:e200068. Epub 2020 Jul 6.

Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Introduction: The relationships between the social indicators (SIs) that determine food insecurity (FI) have not been described yet. This systematic review aims to identify which SIs are associated with FI in Brazilian households and how these relationships are explained.

Methods: The research protocol was registered on the International Prospective Register of Systematic Reviews (PROSPERO - CRD42018106527). Read More

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http://dx.doi.org/10.1590/1980-549720200068DOI Listing

Curcumin encapsulated colloidal amphiphilic block co-polymeric nanocapsules: colloidal nanocapsules enhance photodynamic and anticancer activities of curcumin.

Photochem Photobiol Sci 2020 Jul 8. Epub 2020 Jul 8.

Department of Chemistry, American University of Beirut, Beirut, Lebanon.

Curcumin-based novel colloidal nanocapsules were prepared from amphiphilic poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (F108). These colloidal nanocapsules appeared as spherical particles with size ranging between 270 and 310 nm. Curcumin fluorescence spectra exhibited an aggregation-induced 23 nm red-shift of the emission maximum in addition to the enhancement of the fluorescence quantum yield in these nanocapsules. Read More

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http://dx.doi.org/10.1039/d0pp00032aDOI Listing

The use of radiological imaging alongside reverse transcriptase PCR in diagnosing novel coronavirus disease 2019: a narrative review.

Future Microbiol 2020 Jul 8. Epub 2020 Jul 8.

Department of Medicine, Royal college of Surgeons in Ireland - Medical University of Bahrain, Al Sayh Muharraq Governorate, Bahrain.

The diagnosis of novel coronavirus disease 2019 (COVID-19) has been a challenge in many countries due to nonspecific symptoms and variable incubation period. The current reference test is reverse transcriptase PCR. Many studies have reported high sensitivities of CT scans and suggested that they can be used in the diagnosis of COVID-19 alongside reverse transcriptase PCR. Read More

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http://dx.doi.org/10.2217/fmb-2020-0098DOI Listing

Spectrum of gene mutations identified by targeted next-generation sequencing in Chinese leukemia patients.

Mol Genet Genomic Med 2020 Jul 7:e1369. Epub 2020 Jul 7.

Department of General Practice, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, Hainan, P.R. China.

Background: Despite targeted sequencing have identified several mutations for leukemia, there is still a limit of mutation screening for Chinese leukemia. Here, we used targeted next-generation sequencing for testing the mutation patterns of Chinese leukemia patients.

Methods: We performed targeted sequencing of 504 tumor-related genes in 109 leukemia samples to identify single-nucleotide variants (SNVs) and insertions and deletions (INDELs). Read More

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http://dx.doi.org/10.1002/mgg3.1369DOI Listing

Efficacy and Safety of Upadacitinib Monotherapy in Methotrexate-naïve Patients with Moderately to Severely Active Rheumatoid Arthritis (SELECT-EARLY): A Randomized, Double-blind, Active-comparator, Multi-center, Multi-country Trial.

Arthritis Rheumatol 2020 Jul 8. Epub 2020 Jul 8.

Stanford University, Palo Alto, CA, USA.

Objective: The SELECT-EARLY trial studied the effect of upadacitinib, an oral, reversible, JAK inhibitor, as monotherapy in patients with predominantly early rheumatoid arthritis who are naïve or have limited exposure to methotrexate.

Methods: Patients were randomized (n=947, 1:1:1) to once-daily upadacitinib (15mg or 30mg) or weekly methotrexate (7.5-20mg/week) for 24 weeks. Read More

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http://dx.doi.org/10.1002/art.41384DOI Listing

Non-invasive risk scores do not reliably identify future cirrhosis or hepatocellular carcinoma in Type 2 diabetes: The Edinburgh Type 2 Diabetes Study.

Liver Int 2020 Jul 7. Epub 2020 Jul 7.

Western General Hospital, Edinburgh, UK.

Background: The incidence of cirrhosis and hepatocellular carcinoma (HCC) is increased in Type 2 diabetes, primarily secondary to non-alcoholic fatty liver disease (NAFLD). European guidelines recommend screening for NAFLD in Type 2 diabetes. American guidelines, while not advocating a screening protocol, suggest using non-invasive markers of fibrosis for risk-stratification and guiding onward referral. Read More

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http://dx.doi.org/10.1111/liv.14590DOI Listing

Associations of Breastfeeding, Maternal Smoking, and Birth Weight With Bone Density and Microarchitecture in Young Adulthood: a 25-Year Birth-Cohort Study.

J Bone Miner Res 2020 Jul 8. Epub 2020 Jul 8.

Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia.

We have found that early-life exposures are associated with areal bone mineral density (aBMD) at ages 8 and 16 years. This study aimed to assess whether these associations persist into young adulthood when peak bone mass (PBM) is achieved and extend this analysis to microarchitecture. Participants were followed from perinatal period to 25 years old (n = 201). Read More

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http://dx.doi.org/10.1002/jbmr.4044DOI Listing