18,603 results match your criteria American Journal of Veterinary Research [Journal]


Pharmacokinetics and safety of zonisamide after oral administration of single and multiple doses to Hispaniolan Amazon parrots (Amazona ventralis).

Am J Vet Res 2019 Feb;80(2):195-200

OBJECTIVE To determine pharmacokinetics after oral administration of single and multiple doses and to assess the safety of zonisamide in Hispaniolan Amazon parrots (Amazona ventralis). ANIMALS 12 adult Hispaniolan Amazon parrots. PROCEDURES Zonisamide (30 mg/kg, PO) was administered once to 6 parrots in a single-dose trial. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.2.195DOI Listing
February 2019
1 Read

Histologic assessment of ligament vascularity and synovitis in dogs with cranial cruciate ligament disease.

Am J Vet Res 2019 Feb;80(2):152-158

Objective: To assess the relationship between histologic degeneration of cranial cruciate ligaments (CCLs) and severity of synovitis and ligament vascularity.

Sample: CCL and synovium from 59 stifle joints (53 dogs).

Procedures: CCL and synovium specimens were obtained from stifle joints of juvenile (15 joints; 12 dogs) and adult (25 joints; 22 dogs) dogs with intact CCLs and dogs with CCL rupture (rCCL; 19 joints; 19 dogs). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.2.152DOI Listing
February 2019

Comparison of computed tomographic attenuation values for epaxial muscles in old and young dogs.

Am J Vet Res 2019 Feb;80(2):174-177

OBJECTIVE To determine whether the degree of CT attenuation of muscle would differ between healthy old and young dogs. ANIMALS 10 healthy old (> 8 years old) and 9 healthy young (1 to 5 years old) Labrador Retrievers with a body condition score of 5 or 6 on a 9-point scale. PROCEDURES CT was performed with the dogs mildly sedated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.2.174DOI Listing
February 2019

Effect of contrast medium injection rate on computed tomography-derived renal perfusion estimates obtained with the maximum slope method in healthy.

Am J Vet Res 2019 Feb;80(2):168-173

OBJECTIVE To evaluate the effect of contrast medium injection rate on CT-derived renal perfusion estimates obtained with the maximum slope method in healthy small dogs. ANIMALS 6 healthy sexually intact male purpose-bred Beagles. PROCEDURES All dogs underwent CT perfusion analysis 3 times in a crossover design, receiving a different contrast medium injection rate (1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.2.168DOI Listing
February 2019
1 Read

Pharmacokinetics of meloxicam during multiple oral or intramuscular dose administration to African grey parrots (Psittacus erithacus).

Am J Vet Res 2019 Feb;80(2):201-207

OBJECTIVE To determine the pharmacokinetics of meloxicam in African grey parrots (Psittacus erithacus) during administration of multiple doses. ANIMALS 6 healthy African grey parrots. PROCEDURES Meloxicam was administered at each of 3 dosages (1 mg/kg, IM, q 24 h, for 7 days; 1 mg/kg, PO, q 24 h, for 12 days; and 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.2.201DOI Listing
February 2019
1 Read

Evaluation of the effects of gas volume and composition on accuracy of volume measurement by two flow sensors and delivery by a piston-driven large-animal ventilator.

Am J Vet Res 2019 Feb;80(2):135-143

OBJECTIVE To evaluate the effects of 4 gas compositions at various volumes (simulated tidal volumes [Vs]) on accuracy of measurements obtained with 2 types of flow sensors and accuracy of gas volume delivery by a piston-driven ventilator. SAMPLE 4 gas mixtures (medical air [21% O:79% N], > 95% O, O-enriched air [30% O:70% N], and heliox [30% O:70% He]). PROCEDURES For each gas mixture, reference Vs of 1 to 8 L were delivered into an anesthetic breathing circuit via calibration syringe; measurements recorded by a Pitot tube-based flow sensor (PTFS) connected to a multiparameter host anesthesia monitor and by a thermal mass flow and volume meter (TMFVM) were compared with the reference values. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.2.135DOI Listing
February 2019
3 Reads

Effect of intracoelomic administration of alfaxalone on the righting reflex and tactile stimulus response of common garter snakes (Thamnophis sirtalis).

Am J Vet Res 2019 Feb;80(2):144-151

Objective: To determine the intracoelemic (ICe) dose of alfaxalone required to induce loss of righting reflex (LRR) in garter snakes (Thamnophis sirtalis) and to evaluate the tactile stimulus response in unanesthetized and alfaxalone-anesthetized snakes.

Animals: 8 healthy mature garter snakes.

Procedures: During the first of 3 phases, snakes received each of 3 doses (10, 20, and 30 mg/kg) of alfaxalone, ICe, with a 2-week washout period between treatments. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.2.144DOI Listing
February 2019

Relationship between breed, hemivertebra subtype, and kyphosis in apparently neurologically normal French Bulldogs, English Bulldogs, and Pugs.

Am J Vet Res 2019 Feb;80(2):189-194

OBJECTIVE To investigate whether hemivertebra subtype as determined via CT was associated with breed and Cobb angle (a measure of the degree of spinal curvature) in apparently neurologically normal French Bulldogs, English Bulldogs, and Pugs. ANIMALS Client-owned French Bulldogs (n = 58), English Bulldogs (30), and Pugs (12) with thoracic hemivertebrae that underwent CT for reasons unrelated to spinal disease. PROCEDURES CT scans of each dog were evaluated, and hemivertebrae were categorized by subtype (ventral aplasia, ventral hypoplasia, lateral aplasia, lateral hypoplasia, ventrolateral aplasia, ventrolateral hypoplasia, ventral and median aplasia, ventral and median hypoplasia, and symmetric hypoplasia). Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.80.2.189
Publisher Site
http://dx.doi.org/10.2460/ajvr.80.2.189DOI Listing
February 2019
1 Read

Evaluation of skin turgor and capillary refill time as predictors of dehydration in exercising dogs.

Am J Vet Res 2019 Feb;80(2):123-128

OBJECTIVE To determine usefulness of skin turgor and capillary refill time (CRT) for predicting changes in hydration status of working dogs after a 15-minute exercise period. ANIMALS 9 exercise-conditioned working dogs between 8 and 108 months of age. PROCEDURES Skin tent time (SkTT; time for tented skin on the forehead to return to an anatomically normal position) and CRT (time for occluded mucous membrane capillary vessels to return to the color visible before occlusion) were measured on dogs in a field setting and by video review. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.2.123DOI Listing
February 2019

Association of catastrophic condylar fracture with bony changes of the third metacarpal bone identified by use of standing magnetic resonance imaging in forelimbs from cadavers of Thoroughbred racehorses in the United States.

Am J Vet Res 2019 Feb;80(2):178-188

OBJECTIVE To compare bony changes of the third metacarpal bone (MC3) of Thoroughbred racehorse cadavers with (cases) or without (controls) catastrophic condylar fracture by use of standing MRI. SAMPLE 140 forelimbs from 26 case horses (both forelimbs) and 88 control horses (single forelimb). PROCEDURES Bone marrow lesions (BMLs), identified as a decrease in T1-weighted (T1W) signal and increases in T2*-weighted (T2*W) and short tau inversion recovery (STIR) signals, and dense bone volume percentage (DBVP), identified as decreases in T1W, T2*W, and STIR signals, in the distopalmar aspect of MC3 were recorded. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.2.178DOI Listing
February 2019

Effects of the fraction of inspired oxygen on alfaxalone-sedated inland bearded dragons (Pogona vitticeps).

Am J Vet Res 2019 Feb;80(2):129-134

OBJECTIVE To evaluate the effects of providing 100% O, compared with provision of room air, in sedated spontaneously breathing inland bearded dragons (Pogona vitticeps). ANIMALS 8 adult bearded dragons. PROCEDURES Animals were sedated with alfaxalone (20 mg/kg, SC) and received 21% O (equivalent to room air) or 100% O via face mask (flow rate, 1 L/min) in a randomized, blinded, complete crossover study (2-week interval between treatments). Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.80.2.129
Publisher Site
http://dx.doi.org/10.2460/ajvr.80.2.129DOI Listing
February 2019
5 Reads

Perfusion-weighted and diffusion-weighted magnetic resonance imaging of the liver, spleen, and kidneys of healthy adult male cats.

Am J Vet Res 2019 Feb;80(2):159-167

OBJECTIVE To describe perfusion and diffusion characteristics of the liver, spleen, and kidneys of healthy adult male cats as determined by morphological, perfusion-weighted, and diffusion-weighted MRI. ANIMALS 12 healthy adult male cats. PROCEDURES Each cat was anesthetized. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.2.159DOI Listing
February 2019
1 Read

Reference limits for hepatic bile duct-to-arteriole and bile duct-to-portal tract ratios in healthy cats.

Am J Vet Res 2019 Jan;80(1):15-23

OBJECTIVE To establish reference limits for hepatic bile duct-to-arteriole ratio (BD:A) and bile duct-to-portal tract ratio (BD:PT) in healthy cats and assess whether these parameters could be used to support a diagnosis of biliary ductopenia in cats. SAMPLE Hepatic biopsy samples from healthy cats (n = 20) and cats with ductopenia (2). PROCEDURES Hepatic biopsy samples from healthy cats were used to count the number of bile ducts and hepatic arterioles in 20 portal tracts for each cat. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.1.15DOI Listing
January 2019
1 Read

Use of a modified passive leg-raising maneuver to predict fluid responsiveness during experimental induction and correction of hypovolemia in healthy isoflurane-anesthetized pigs.

Am J Vet Res 2019 Jan;80(1):24-32

OBJECTIVE To evaluate the use of a modified passive leg-raising maneuver (PLRM) to predict fluid responsiveness during experimental induction and correction of hypovolemia in isoflurane-anesthetized pigs. ANIMALS 6 healthy male Landrace pigs. PROCEDURES Pigs were anesthetized with isoflurane, positioned in dorsal recumbency, and instrumented. Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.80.1.24
Publisher Site
http://dx.doi.org/10.2460/ajvr.80.1.24DOI Listing
January 2019
2 Reads

Investigation of effects of omeprazole on the fecal and gastric microbiota of healthy adult horses.

Am J Vet Res 2019 Jan;80(1):79-86

OBJECTIVE To determine the effects of oral omeprazole administration on the fecal and gastric microbiota of healthy adult horses. ANIMALS 12 healthy adult research horses. PROCEDURES Horses were randomly assigned to receive omeprazole paste (4 mg/kg, PO, q 24 h) or a sham (control) treatment (tap water [20 mL, PO, q 24 h]) for 28 days. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.1.79DOI Listing
January 2019
1 Read

Morphometric evaluation of the portal vein by means of abdominal computed tomographic angiography in dogs free of vascular anomalies.

Am J Vet Res 2019 Jan;80(1):69-73

OBJECTIVE To determine the mean diameter of the main portal vein (PV) in healthy dogs by use of CT angiography, identify any associations between PV diameter and certain dog characteristics, and validate a clinically valuable ratio for quantifying the size of the PV. ANIMALS 100 dogs with no hepatic, cardiac, or vascular anomalies that underwent abdominal CT angiography. PROCEDURES Diameters of the main PV, abdominal aorta (Ao), and caudal vena cava (CVC) were measured by 2 observers at a defined location on postcontrast CT angiographic images in axial, sagittal, and transverse planes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.1.69DOI Listing
January 2019
1 Read

Determination of the pharmacokinetics of a single oral dose of trazodone and its effect on the activity level of domestic pigeons (Columba livia).

Am J Vet Res 2019 Jan;80(1):102-109

Objective: To determine the pharmacokinetics of a single oral dose of trazodone and its effect on the activity of domestic pigeons (Columba livia).

Animals: 6 healthy adult male domestic pigeons.

Procedures: During the first of 3 experiments, birds received orally administered trazodone at doses ranging from 3 to 30 mg/kg to determine the dose for subsequent experiments. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.1.102DOI Listing
January 2019
1 Read

JAVMA New digest.

Authors:

Am J Vet Res 2019 Jan;80(1):4-9

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.80.1.4
Publisher Site
http://dx.doi.org/10.2460/ajvr.80.1.4DOI Listing
January 2019
2 Reads

Effect of acute volume overload on echocardiographic indices of right ventricular function and dyssynchrony assessed by use of speckle tracking echocardiography in healthy dogs.

Am J Vet Res 2019 Jan;80(1):51-60

OBJECTIVE To determine the relationship between acute volume overload and echocardiographic indices of right ventricular (RV) function and dyssynchrony in healthy dogs. ANIMALS 7 healthy Beagles. PROCEDURES Right heart catheterization and echocardiography were performed in 7 healthy anesthetized Beagles at baseline and after induction of volume overload. Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.80.1.51
Publisher Site
http://dx.doi.org/10.2460/ajvr.80.1.51DOI Listing
January 2019
5 Reads

Changes in pupil size and intraocular pressure after topical application of 0.5% tropicamide to the eyes of dogs sedated with butorphanol.

Am J Vet Res 2019 Jan;80(1):95-101

Objective: To assess changes in pupil size and intraocular pressure (IOP) following topical application of a 0.5% tropicamide solution in the eyes of healthy butorphanol-sedated dogs.

Animals: 12 healthy adult Beagles. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.1.95DOI Listing
January 2019
1 Read

In vitro effect of 20% N-acetylcysteine on the viscosity of normal canine bile.

Am J Vet Res 2019 Jan;80(1):74-78

OBJECTIVE To evaluate the in vitro effect of 20% N-acetylcysteine (NAC) on the viscosity of normal canine bile. ANIMALS Bile samples obtained from 10 adult dogs euthanized for reasons unrelated to biliary disease. PROCEDURES Each sample was centrifuged to remove particulates, then divided into 3 aliquots. Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.80.1.74
Publisher Site
http://dx.doi.org/10.2460/ajvr.80.1.74DOI Listing
January 2019
2 Reads

Esophageal insufflation computed tomography in clinically normal dogs.

Am J Vet Res 2019 Jan;80(1):61-68

OBJECTIVE To assess the feasibility of esophageal insufflation CT (EICT) for evaluation of the esophagus in dogs. ANIMALS 7 clinically normal adult Beagles. PROCEDURES Each dog was anesthetized twice with 1 week between anesthesia sessions. Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.80.1.61
Publisher Site
http://dx.doi.org/10.2460/ajvr.80.1.61DOI Listing
January 2019
2 Reads

Effects of intravenous administration of tiletamine-zolazepam, alfaxalone, ketamine-diazepam, and propofol for induction of anesthesia on cardiorespiratory and metabolic variables in healthy dogs before and during anesthesia maintained with isoflurane.

Am J Vet Res 2019 Jan;80(1):33-44

OBJECTIVE To compare effects of tiletamine-zolazepam, alfaxalone, ketamine-diazepam, and propofol for anesthetic induction on cardiorespiratory and acid-base variables before and during isoflurane-maintained anesthesia in healthy dogs. ANIMALS 6 dogs. PROCEDURES Dogs were anesthetized with sevoflurane and instrumented. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.1.33DOI Listing
January 2019
1 Read

Evaluation of vaporized hydrogen peroxide sterilization on the in vitro efficacy of meropenem-impregnated polymethyl methacrylate beads.

Am J Vet Res 2019 Jan;80(1):45-50

OBJECTIVE To evaluate the effects of vaporized hydrogen peroxide (VHP) sterilization on the in vitro antimicrobial efficacy of meropenem-impregnated polymethyl methacrylate (M-PMMA) beads. SAMPLE 6-mm-diameter polymethyl methacrylate beads that were or were not impregnated with meropenem. PROCEDURES Meropenem-free polymethyl methacrylate and M-PMMA beads were sterilized by use of an autoclave or VHP or remained unsterilized. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.1.45DOI Listing
January 2019
1 Read

Survival of Mycobacterium bovis during forage ensiling.

Am J Vet Res 2019 Jan;80(1):87-94

OBJECTIVE To determine whether Mycobacterium bovis remains viable in ensiled forages. SAMPLE Alfalfa, mixed mostly grass, and corn silages. PROCEDURES For each of 10 sampling days, six 250-g replicate samples of each feedstuff were created and placed in a film pouch that could be vacuum sealed to simulate the ensiling process. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.1.87DOI Listing
January 2019
1 Read

Letters to the Editor.

Authors:

Am J Vet Res 2019 Jan;80(1):10-11

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.80.1.10DOI Listing
January 2019
2 Reads

Sedative and cardiopulmonary effects of buccally administered detomidine gel and reversal with atipamezole in dogs.

Am J Vet Res 2018 Dec;79(12):1253-1260

OBJECTIVE To evaluate hemodynamic, respiratory, and sedative effects of buccally administered detomidine gel and reversal with atipamezole in dogs. ANIMALS 8 adult purpose-bred dogs. PROCEDURES Arterial and venous catheters were placed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.79.12.1253DOI Listing
December 2018
3 Reads

Effect of pneumoperitoneum with warmed humidified or standard-temperature carbon dioxide during laparoscopy on core body temperature, cardiorespiratory and thromboelastography variables, systemic inflammation, peritoneal response, and signs of postoperative pain in healthy mature dogs.

Am J Vet Res 2018 Dec;79(12):1321-1334

OBJECTIVE To evaluate effects of pneumoperitoneum created with warmed humidified CO (WHCO) during laparoscopy on core body temperature, cardiorespiratory and thromboelastography variables, systemic inflammation, peritoneal response, and signs of postoperative pain in healthy mature dogs. ANIMALS 6 mature purpose-bred dogs. PROCEDURES In a randomized crossover study, each dog was anesthetized twice, and pneumoperitoneum was created with standard-temperature CO (STCO; 22°C and 0% relative humidity) and WHCO (37°C and 98% relative humidity). Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.79.12.1321
Publisher Site
http://dx.doi.org/10.2460/ajvr.79.12.1321DOI Listing
December 2018
8 Reads

Evaluation of animal-to-animal and community contact structures determined by a real-time location system for correlation with and prediction of new bovine respiratory disease diagnoses in beef cattle during the first 28 days after feedlot entry.

Am J Vet Res 2018 Dec;79(12):1277-1286

OBJECTIVE To determine whether animal-to-animal and community contact patterns were correlated with and predictive for bovine respiratory disease (BRD) in beef steers during the first 28 days after feedlot entry. ANIMALS 70 weaned beef steers (mean weight, 248.9 kg). Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.79.12.1277
Publisher Site
http://dx.doi.org/10.2460/ajvr.79.12.1277DOI Listing
December 2018
13 Reads

In vitro mechanical evaluation of three transfixation pin-cast constructs applied to equine forelimbs.

Am J Vet Res 2018 Dec;79(12):1287-1297

OBJECTIVE To compare strain at the bone-pin and cast-pin interfaces among 3 transfixation pin-cast constructs applied to equine forelimbs. ANIMALS 15 forelimbs from 15 adult horses. PROCEDURES Limbs were randomly assigned to 1 of 3 constructs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.79.12.1287DOI Listing
December 2018
1 Read

Influence of injection protocol and measurement technique on computed tomographic assessment of glomerular filtration rate in healthy Beagles.

Am J Vet Res 2018 Dec;79(12):1298-1305

OBJECTIVE To compare values of CT-derived glomerular filtration rate (GFR) determined by 3 contrast-medium injection protocols and 4 measurement techniques in healthy Beagles. ANIMALS 9 healthy Beagles (mean ± SD weight, 13.2 ± 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.79.12.1298DOI Listing
December 2018
1 Read

Effect of a constant rate infusion of remifentanil hydrochloride on left ventricular systolic and diastolic function in propofol-anesthetized dogs.

Am J Vet Res 2018 Dec;79(12):1261-1267

OBJECTIVE To assess the effects of a constant rate infusion (CRI) of remifentanil hydrochloride on left ventricular systolic and diastolic function in healthy propofol-anesthetized dogs. ANIMALS 6 healthy Beagles. PROCEDURES Each dog underwent 2 experimental treatments separated by a 7-day interval. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.79.12.1261DOI Listing
December 2018
6 Reads

Evaluation of the thermal antinociceptive effects and pharmacokinetics after intramuscular administration of buprenorphine hydrochloride to cockatiels (Nymphicus hollandicus).

Am J Vet Res 2018 Dec;79(12):1239-1245

OBJECTIVE To evaluate thermal antinociceptive effects and pharmacokinetics of buprenorphine hydrochloride after IM administration to cockatiels (Nymphicus hollandicus). ANIMALS 16 adult (≥ 2 years old) cockatiels (8 males and 8 females). PROCEDURES Buprenorphine hydrochloride (0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.79.12.1239DOI Listing
December 2018
6 Reads

Activation of chicken macrophages during in vitro stimulation and expression of immune genes.

Am J Vet Res 2018 Dec;79(12):1306-1312

OBJECTIVE To characterize activation and expression of immune genes of chicken macrophages after in vitro stimulation with lipopolysaccharide (LPS) and mouse erythrocytes. ANIMALS Five 15-day-old chickens and 2 BALB/c mice. PROCEDURES Macrophages were extracted from chicken bone marrow or peripheral blood and then stimulated with cytokines secreted from cell lines L929 and HD11. Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.79.12.1306
Publisher Site
http://dx.doi.org/10.2460/ajvr.79.12.1306DOI Listing
December 2018
16 Reads

Pharmacokinetics and pharmacodynamics of oral pradofloxacin administration in dogs.

Am J Vet Res 2018 Dec;79(12):1268-1276

OBJECTIVE To determine whether target values for pharmacokinetic-pharmacodynamic (PK-PD) indices against selected canine pathogens were achievable for pradofloxacin in various canine fluids and leukocytes. ANIMALS 8 healthy adult hounds (experiments 1 and 2) and 6 healthy adult dogs (experiment 3). PROCEDURES In 3 experiments, pradofloxacin (3, 6, or 12 mg/kg) and enrofloxacin (5 or 10 mg/kg) were orally administered once a day for 5 days, and blood, interstitial fluid (ISF), and other fluid samples were collected at various points. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.79.12.1268DOI Listing
December 2018
14 Reads

Assessment of sedation after intranasal administration of midazolam and midazolam-butorphanol in cockatiels (Nymphicus hollandicus).

Am J Vet Res 2018 Dec;79(12):1246-1252

OBJECTIVE To compare sedation in cockatiels (Nymphicus hollandicus) after intranasal administration of midazolam and midazolam-butorphanol. ANIMALS 9 healthy adult cockatiels. PROCEDURES A randomized, controlled, blinded, complete crossover study was conducted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.79.12.1246DOI Listing
December 2018
6 Reads

Quantitative assessment of intravenous regional limb perfusion of tiludronate as an adjunctive treatment for lameness caused by navicular syndrome in horses.

Am J Vet Res 2018 Dec;79(12):1313-1320

OBJECTIVE To determine effects for 2 IV regional limb perfusion (IVRLP) protocols involving tiludronate on lameness of horses with navicular syndrome. ANIMALS 15 horses with bilateral forelimb navicular syndrome. PROCEDURES Shoeing and anti-inflammatory injection into the distal interphalangeal joint (DIPJ) of both forelimbs (day 0) were performed on all horses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.79.12.1313DOI Listing
December 2018
7 Reads

Effects of a surgical sealant on leakage pressure and circumference of fresh canine cadaver small intestinal anastomoses.

Am J Vet Res 2018 Dec;79(12):1335-1340

OBJECTIVE To evaluate the effect of a bovine albumin-derivatized glutaraldehyde (BA-DG) biopolymer sealant on leakage pressures of intestinal anastomoses in jejunal tissue collected from fresh canine cadavers and to evaluate changes in circumference and cross-sectional area of the anastomotic site resulting from sealant application. SAMPLE 24 jejunal anastomoses from 4 fresh canine cadavers. PROCEDURES Jejunal tissue specimens were collected, and adjacent segment anastomoses were created within 12 hours after euthanasia of each dog. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.79.12.1335DOI Listing
December 2018
1 Read

Comparison of bronchoscopic and nonbronchoscopic bronchoalveolar lavage in healthy cats.

Am J Vet Res 2018 Nov;79(11):1209-1216

OBJECTIVE To compare bronchoalveolar lavage (BAL) accomplished by use of a bronchoscopic (B-BAL) and a nonbronchoscopic (NB-BAL) technique in healthy cats. ANIMALS 12 healthy cats. PROCEDURES Two BALs were performed in a randomized order 2 weeks apart in each cat. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.79.11.1209DOI Listing
November 2018
1 Read

Analytic characterization of flow cytometric assays for detection of immunoglobulin G on canine erythroid cells, including detection of dog erythrocyte antigen 1 on erythroid precursors.

Am J Vet Res 2018 Nov;79(11):1123-1132

OBJECTIVE To develop and characterize flow cytometric assays for detecting IgG bound to canine erythrocytes and bone marrow erythroid precursors. SAMPLE Blood samples from 20 healthy and 61 sick dogs with (n = 33) or without (28) immune-mediated hemolytic anemia (IMHA) and bone marrow samples from 14 healthy dogs. PROCEDURES A flow cytometric assay for measurement of IgG on RBCs was developed, and appropriate positive control cells were generated. Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.79.11.1123
Publisher Site
http://dx.doi.org/10.2460/ajvr.79.11.1123DOI Listing
November 2018
11 Reads

Risk of environmental exposure to small coccidia from wild canid feces in rural Ohio.

Am J Vet Res 2018 Nov;79(11):1179-1187

OBJECTIVE To determine the extent of environmental exposure to heteroxenous coccidia from wild canid feces in southeastern Ohio. SAMPLE 285 presumed wild canid fecal samples collected across an ecological system in southeastern Ohio. PROCEDURES Morphological classification and molecular analysis were used to determine the canid genus for collected fecal samples. Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.79.11.1179
Publisher Site
http://dx.doi.org/10.2460/ajvr.79.11.1179DOI Listing
November 2018
14 Reads

Three-dimensional assessment of the influence of juvenile pubic symphysiodesis on the pelvic geometry of dogs.

Am J Vet Res 2018 Nov;79(11):1217-1225

OBJECTIVE To evaluate the 3-D geometry of canine pelves and to characterize the long-term effects of juvenile pubic symphysiodesis (JPS) on pelvic geometry by comparing the pelvic configuration between littermates that did and did not undergo the procedure. ANIMALS 24 Labrador Retriever, Golden Retriever, or Labrador Retriever-Golden Retriever crossbred service dogs from 13 litters. PROCEDURES At 16 weeks old, puppies with a hip joint distraction index ≥ 0. Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.79.11.1217
Publisher Site
http://dx.doi.org/10.2460/ajvr.79.11.1217DOI Listing
November 2018
16 Reads

Effects of furosemide administration to water-deprived inland bearded dragons (Pogona vitticeps).

Am J Vet Res 2018 Nov;79(11):1204-1208

OBJECTIVE To evaluate the diuretic effects and associated changes in hematologic and plasma biochemical values following SC furosemide administration to water-deprived inland bearded dragons (Pogona vitticeps). ANIMALS 9 bearded dragons. PROCEDURES In a crossover study design, furosemide (5 or 10 mg/kg) was administered SC every 12 hours for 4 doses or no treatment (control treatment) was provided for the same period. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2460/ajvr.79.11.1204DOI Listing
November 2018
4 Reads

Effects of a nutrient-enriched water with and without poultry flavoring on water intake, urine specific gravity, and urine output in healthy domestic cats fed a dry kibble diet.

Am J Vet Res 2018 Nov;79(11):1150-1159

OBJECTIVE To investigate water intake and urine measures in healthy cats provided free-choice access to a nutrient-enriched water with (NWP) or without (NW) added poultry flavoring offered at 3 different volumes in addition to tap water (TW). ANIMALS 36 domestic shorthair cats. PROCEDURES Control group cats (n = 4) received dry food with TW ad libitum throughout the study. Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.79.11.1150
Publisher Site
http://dx.doi.org/10.2460/ajvr.79.11.1150DOI Listing
November 2018
2 Reads

Evaluation of liver lesions by use of shear wave elastography and computed tomography perfusion imaging after radiofrequency ablation in clinically normal dogs.

Am J Vet Res 2018 Nov;79(11):1140-1149

OBJECTIVE To evaluate acute changes of the liver by use of shear wave elastography (SWE) and CT perfusion after radiofrequency ablation (RFA). ANIMALS 7 healthy Beagles. PROCEDURES RFA was performed on the liver (day 0). Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.79.11.1140
Publisher Site
http://dx.doi.org/10.2460/ajvr.79.11.1140DOI Listing
November 2018
26 Reads

Quantitation of anti-Pythium insidiosum antibodies before and after administration of an immunotherapeutic product to healthy dogs.

Am J Vet Res 2018 Nov;79(11):1160-1165

OBJECTIVE To evaluate the effect of an immunotherapeutic product on concentrations of anti-Pythium insidiosum antibodies in dogs. ANIMALS 7 healthy hound-crossbreds. PROCEDURES Antibody concentrations were evaluated before (day 0) and after administration of the immunotherapeutic product. Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.79.11.1160
Publisher Site
http://dx.doi.org/10.2460/ajvr.79.11.1160DOI Listing
November 2018
2 Reads

Effect of age on the pharmacokinetics and distribution of tulathromycin in interstitial and pulmonary epithelial lining fluid in healthy calves.

Am J Vet Res 2018 Nov;79(11):1193-1203

OBJECTIVE To compare the plasma pharmacokinetics of tulathromycin between 3-week-old (preweaned) and 6-month-old (weaned) calves and to characterize the distribution of tulathromcyin into pulmonary epithelial lining fluid (PELF) and interstitial fluid (ISF) of preweaned and weaned calves following SC administration of a single dose (2.5 mg/kg). ANIMALS 8 healthy 3-week-old and 8 healthy 6-month-old Holstein steers. Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.79.11.1193
Publisher Site
http://dx.doi.org/10.2460/ajvr.79.11.1193DOI Listing
November 2018
10 Reads

Cell-mediated and humoral immune responses to bovine herpesvirus type 1 and bovine viral diarrhea virus in calves following administration of a killed-virus vaccine and bovine herpesvirus type 1 challenge.

Am J Vet Res 2018 Nov;79(11):1166-1178

OBJECTIVE To evaluate cell-mediated and humoral immune responses of calves receiving 2 doses of a dual-adjuvanted vaccine containing inactivated bovine herpesvirus type 1 (BHV1) and bovine viral diarrhea virus types 1 (BVDV1) and 2 (BVDV2) before and after exposure to BHV1. ANIMALS 24 Holstein steers negative for anti-BHV1 antibodies and proliferative cell-mediated immune responses against BHV1 and BVDV. PROCEDURES Calves were randomly assigned to 3 groups. Read More

View Article

Download full-text PDF

Source
https://avmajournals.avma.org/doi/10.2460/ajvr.79.11.1166
Publisher Site
http://dx.doi.org/10.2460/ajvr.79.11.1166DOI Listing
November 2018
6 Reads