Search Our Scientific Publications & Authors

Sportverletz Sportschaden 2020 Jul 14. Epub 2020 Jul 14.

American University of Beirut Medical Center, Beirut.

Background:  The deltoid is a large triangular muscle at the shoulder. It attaches proximally to the clavicle, acromion and scapula, while distally it attaches to the lateral deltoid tuberosity. Ruptures are rare, and the literature only reports cases of proximal detachment. Read More

J Knee Surg 2020 Jul 14. Epub 2020 Jul 14.

Department of Anesthesiology & Critical Care Medicine, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia.

Revision total knee arthroplasty (TKA) is an increasingly common procedure and is effective in treating knee osteoarthritis, but it has higher complication rates than primary TKA. Anesthetic choice poses perioperative risk that has been extensively studied in primary TKA, showing favorable results for regional anesthesia compared with general anesthesia. The impact of anesthetic choice in revision TKAs is not well studied. Read More

J Parasitol 2019 Oct;105(5):671-685

Aquatic Parasitology Laboratory, School of Fisheries, Aquaculture, and Aquatic Sciences, College of Agriculture, Auburn University, Auburn, Alabama, 36849.

Herein we describe a new species of turtle blood fluke (TBF) and propose a new genus to accommodate it, Pitiutrema revelae n. gen., n. Read More

J Parasitol 2019 Oct;105(5):769-782

U.S. Geological Survey-National Wildlife Health Center, 6006 Schroeder Road, Madison, Wisconsin 53711.

Truttaedacnitis truttae is a cucullanid nematode of primarily salmonine fishes. Brown trout (Salmo trutta) in Europe reportedly become parasitized by ingesting lampreys (Lampetra planeri) carrying infective larvae. However, our field and laboratory observations suggested that North American specimens of T. Read More

J Parasitol 2019 Oct;105(5):686-692

Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Thad Cochran National Warmwater Aquaculture Center, Delta Research and Extension Center, Mississippi State University, 127 Experiment Station Road, Stoneville, Mississippi 38776.

There are multiple Henneguya spp. (Myxozoa: Myxobolidae) endemic to North American catfish aquaculture that affect the gills of channel catfish and their hybrids. These parasites are morphologically similar, and confusion exists regarding the predilection sites and pathologic changes associated with different species. Read More

Clin Neurol Neurosurg 2020 Jul 7;195:106074. Epub 2020 Jul 7.

Division of Neurosurgery, Department of Surgery, American University of Beirut Medical Center, Lebanon. Electronic address:

Hypothalamic hamartomas (HH) are rare, non-neoplastic heterotopic tissues which contains normal neurons and glia including oligodendrocytes and fibrillary astrocytes but in an abnormal distribution. They arise from the floor of the third ventricle, tuber cinereum, or mammillary bodies. Estimated incidence ranges from 1 in 50,000 to 1 in 1,000,000. Read More

J Surg Res 2020 Jul 10;255:632-640. Epub 2020 Jul 10.

Case Western Reserve University School of Medicine, Cleveland, OH; University Hospitals Cleveland Medical Center/UH-RISES: Research in Surgical Outcomes & Effectiveness Center), Cleveland, OH. Electronic address:

Background: Anorectal procedures are frequently performed and have the potential to be particularly painful. There are no evidence-based guidelines regarding opioid prescribing after anorectal surgery and limited data on how surgeons determine opioid prescriptions after anorectal procedures. We hypothesize significant variations in prescribing practices. Read More

Sci Total Environ 2020 Jul 6;743:140764. Epub 2020 Jul 6.

Program in Public Health, University of California, Irvine, CA 92697, USA; Center for Occupational and Environmental Health, University of California, Irvine 92617, CA, USA. Electronic address:

Background: Lead (Pb) exposure is a problem that disproportionately impacts low-income communities and communities of color. We applied a community-based participatory research approach to assess the distribution of soil Pb concentrations and related social vulnerabilities across Census tracts in Santa Ana, CA.

Methods: Soil Pb samples (n = 1528) were collected by the ¡Plo-NO! Santa Ana! Lead-Free Santa Ana! partnership in 2018 across Santa Ana, CA, at a high spatial resolution and measured using XRF analysis. Read More

J Pediatr 2020 Jul 11. Epub 2020 Jul 11.

Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine, Children's Hospital Colorado, Aurora, CO, United States.

Objectives: To identify predictors of portal hypertension, liver transplantation, and death in North American youth with alpha-1-antitrypsin (AAT) deficiency, and compare with AAT deficiency patients elsewhere.

Study Design: The Childhood Liver Disease Research Network (ChiLDReN) Longitudinal Observational Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) is a prospective, cohort study of pediatric cholestatic liver diseases, including AAT deficiency, enrolling PIZZ and PISZ subjects 0-25 years of age seen since November 2007 at 17 tertiary care centers in the US and Canada. Data from standard-of-care baseline and annual follow-up visits were recorded from medical records, history, physical examination, and laboratory studies. Read More

J Shoulder Elbow Surg 2020 Jul 11. Epub 2020 Jul 11.

Department of Orthopaedic Surgery; Shoulder Service, University of Texas Southwestern Medical Center, Dallas, Texas, USA. Electronic address:

Purpose: The purpose of this study was to determine the rate of short-term complications after TEA and identify predictors of readmission and reoperation. We hypothesized that TEA performed for acute elbow trauma would have higher rates of 30-day readmission and reoperation than TEA for osteoarthritis.

Methods: Using the National Surgical Quality Improvement (NSQIP) database years 2011-2017, we identified patients undergoing TEA for fracture, osteoarthritis, or inflammatory arthritis. Read More

Ophthalmology 2020 Jul 11. Epub 2020 Jul 11.

CDC, Division of Diabetes Translation, Vision Health Initiative, Atlanta, GA.

Objective: Lay the groundwork for future survey validation and harmonization efforts by comparing prevalence rates of self-reported visual impairment (VI) and blindness measured across federally-funded national surveys by age-groups and to prevalence rates of presenting impairment and blindness measured by physical examination.

Design: Cross-sectional comparison of national surveys.

Participants: Participants in: 2016 American Community Survey, the 2016 Behavioral Risk Factor Surveillance System, the 2016 National Health Interview Survey, the 1999-2008 National Health and Nutrition Examination Survey (NHANES), and the 2016 National Survey of Children's Health. Read More

J Thorac Oncol 2020 Jul 11. Epub 2020 Jul 11.

Monash University and Monash Health, Melbourne, Victoria/AU.

Introduction: Lung neuroendocrine tumors (LNETs) are uncommon cancers and there is a paucity of randomized evidence to guide practice. As a result, current guidelines from different neuroendocrine tumor societies vary considerably. There is a need to update and harmonise global consensus guidelines. Read More

Am J Infect Control 2020 Jul 11. Epub 2020 Jul 11.

Preventive Medicine Unit, Infanta Sofía University Hospital, Paseo de Europa, 34, 28702 San Sebastián de los Reyes (Madrid), Spain; Universidad Europea, Avda. Fernando Alonso, 8 28108 Alcobendas (Madrid), Spain. Electronic address:

Objectives: In 2019 Chinese authorities alerted of the appearance of a cluster of cases of unknown pneumonia related to a new type of coronavirus. Spain is among the most affected countries. Our aim is to describe the cases of COVID-19 at Infanta Sofía University Hospital (Madrid), a public secondary hospital that increased its hospital beds to provide assistance during the outbreak. Read More

Nurs Womens Health 2020 Jul 11. Epub 2020 Jul 11.

Objective: To increase clinician adherence to mammography screening guidelines.

Design: Quality improvement initiative.

Setting/local Problem: At a nurse practitioner-led primary care practice, a chart audit of adherence to American Cancer Society mammography screening guidelines indicated a 12% adherence rate for clinicians writing mammography orders. Read More

J Bone Miner Res 2020 Jun 15. Epub 2020 Jun 15.

Endocrine Unit, Massachusetts General Hospital, Boston, MA, USA.

Roux-en-Y gastric bypass (RYGB) instigates high-turnover bone loss in the initial 5 years after surgery, whereas skeletal changes after adjustable gastric banding (AGB) are less pronounced. Long-term skeletal data are scarce, and the mechanisms of bone loss remain unclear. We sought to examine bone density and microarchitecture in RYGB and AGB patients a decade after surgery and to determine whether prior published reports of bone loss represent an appropriate adaptation to new postsurgical weight. Read More

JAMA Netw Open 2020 Jul 1;3(7):e209418. Epub 2020 Jul 1.

Educational Commission for Foreign Medical Graduates, Philadelphia, Pennsylvania.

Importance: Historically, the US physician workforce has included a large number of international medical graduates (IMGs). Recent US immigration policies may affect the inflow of IMGs, particularly those who are citizens of Muslim-majority nations.

Objectives: To provide an overview of the characteristics of IMGs from Muslim-majority nations, including their contributions to the US physician workforce, and to describe trends in the number of applications for certification to the Educational Commission for Foreign Medical Graduates between 2019 and 2018, both overall and for citizens of Muslim-majority nations. Read More

JAMA Netw Open 2020 Jul 1;3(7):e209393. Epub 2020 Jul 1.

Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts.

Importance: Trauma is the leading cause of death for US individuals younger than 45 years, and uncontrolled hemorrhage is a major cause of trauma mortality. The US military's medical advancements in the field of prehospital hemorrhage control have reduced battlefield mortality by 44%. However, despite support from many national health care organizations, no integrated approach to research has been made regarding implementation, epidemiology, education, and logistics of prehospital hemorrhage control by layperson immediate responders in the civilian sector. Read More

Clin Infect Dis 2020 Jul 14. Epub 2020 Jul 14.

Department of Laboratory Medicine, University of California, San Francisco, CA, USA.

Background: SARS-CoV-2 infection can be detected indirectly by measuring the host immune response. For some viruses, antibody concentrations correlate with host protection and viral neutralization, but in rare cases, anti-viral antibodies can promote disease progression. Elucidation of the kinetics and magnitude of the SARS-CoV-2 antibody response is essential to understand the pathogenesis of COVID-19 and identify potential therapeutic targets. Read More

J Vis 2020 Jul;20(7):10

Computer Science, Cornell University, Ithaca, NY, USA.

When judging the optical properties of a translucent object, humans often look at sharp geometric features such as edges and thin parts. An analysis of the physics of light transport shows that these sharp geometries are necessary for scientific imaging systems to be able to accurately measure the underlying material optical properties. In this article, we examine whether human perception of translucency is likewise affected by the presence of sharp geometry, by confounding our perceptual inferences about an object's optical properties. Read More

PLoS Negl Trop Dis 2020 Jul 14;14(7):e0008045. Epub 2020 Jul 14.

Department of Population Health Sciences, School of Public Health, Georgia State University, Atlanta, Georgia, United States of America.

After being cholera free for over 100 years, Peru experienced an unprecedented epidemic of Vibrio cholerae O1 that began in 1991 and generated multiple waves of disease over several years. We developed a mechanistic transmission model that accounts for seasonal variation in temperature to estimate spatial variability in the basic reproduction number ([Formula: see text]), the initial concentration of vibrios in the environment, and cholera reporting rates. From 1991-1997, cholera spread following a multi-wave pattern, with weekly incidence concentrated during warm seasons. Read More

PLoS One 2020 14;15(7):e0235466. Epub 2020 Jul 14.

Department of Public Health, University of Barcelona, Spain, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.

Introduction: Chagas disease presents bio-psycho-social and cultural determinants for infected patients, their family members, close friends, and society. For this reason, diagnosis and treatment require an active approach and an integral focus, so that we can prevent the disease from creating stigma and exclusion, as is actively promoting access to diagnosis, medical attention and social integration.

Methodology: The study was conducted in the Metropolitan Area of Barcelona (Catalonia, Spain) from 2004 to 2017. Read More

Altern Ther Health Med 2020 Jul 15. Epub 2020 Jul 15.

Context: The drive for a quick return to sport after injury can be great. Athletes look to their sports medicine provider for guidance on a speedy and effective recovery. The sports medicine physician has a number of different treatment options to consider when they turn to their medical armamentarium. Read More

Rev Environ Health 2020 Jul 14. Epub 2020 Jul 14.

Department of Biology, Chemistry & Environmental Sciences, American University of Sharjah, P.O. Box 26666, Sharjah, United Arab Emirates.

Autism spectrum disorder (ASD) has been experiencing an increase in global prevalence in recent decades. While many factors could account for this reality, certain environmental links have been shown to contribute to ASD development and etiology. The Middle East has had relatively little published research on ASD etiology although statistics indicate that ASD affects 1 in 146 births in the United Arab Emirates (UAE). Read More

J Med Internet Res 2020 Jun 15. Epub 2020 Jun 15.

Library, University of British Columbia Okanagan, Kelowna, CA.

Background: The use of e-cigarettes, also known as vaping, has risen exponentially among North American youth in recent years and has become a critical public health concern. The marketing strategies used by e-cigarette companies have been associated with the uptick in use among youth, with video advertisements on TV and other electronic platforms being the most pervasive strategy. It is unknown how these advertisements may be tapping into youth needs and preferences. Read More

J Clin Oncol 2020 Jul 14:JCO2001399. Epub 2020 Jul 14.

Columbia University Medical Center, New York, NY.

Purpose: To update the ASCO guideline on the recommended prevention and treatment approaches in the management of chemotherapy-induced peripheral neuropathy (CIPN) in adult cancer survivors.

Methods: An Expert Panel conducted targeted systematic literature reviews to identify new studies.

Results: The search strategy identified 257 new references, which led to a full-text review of 87 manuscripts. Read More

Am J Respir Crit Care Med 2020 Jul;202(2):e5-e31

Current tobacco treatment guidelines have established the efficacy of available interventions, but they do not provide detailed guidance for common implementation questions frequently faced in the clinic. An evidence-based guideline was created that addresses several pharmacotherapy-initiation questions that routinely confront treatment teams. Individuals with diverse expertise related to smoking cessation were empaneled to prioritize questions and outcomes important to clinicians. Read More

Ann Am Thorac Soc 2020 Jul 14. Epub 2020 Jul 14.

MOUNT SINAI SCHOOL OF MEDICINE, MEDICINE/PULMONARY, CRITICAL CARE AND SLEEP MEDICINE, NEW YORK, New York, United States.

Background: In March 2020, the United States Centers for Disease Control and Prevention recommended cancelation of elective medical services in response to the COVID-19 pandemic. The daily case rate is now declining in many states and there is a need for guidance about the resumption of elective clinical services for patients with lung disease or sleep conditions.

Methods: Volunteers were solicited from the Association of Pulmonary, Critical Care, and Sleep Division Directors (APCCSDD) and American Thoracic Society (ATS). Read More

ACS Chem Neurosci 2020 Jul 14. Epub 2020 Jul 14.

Department of Biology, Chemistry and Environmental Sciences, College of Arts and Sciences, American University of Sharjah, University City, Sharjah, United Arab Emirates.

and macrophages exhibit significant parallels in biochemical, physiological, cellular, and functional aspects. Given the ability of to contribute to the evolutionary gain of pathogenicity of a variety of microbial pathogens, here we propose the use of as a paradigm to study SARS-CoV-2 pathogenicity, infectivity, and evasion of cellular immune defenses. Read More

Magn Reson Med 2020 Jul 14. Epub 2020 Jul 14.

Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.

Purpose: To develop and validate a saturation-delay-inversion recovery preparation, slice tracking and multi-slice based sequence for measuring whole-heart native T .

Method: The proposed free-breathing sequence performs T mapping of multiple left-ventricular slices by slice-interleaved acquisition to collect 10 electrocardiogram-triggered single-shot slice-selective images for each slice. A saturation-delay-inversion recovery pulse is used for T preparation. Read More

Int J Dermatol 2020 Jul 14. Epub 2020 Jul 14.

Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.

J Am Geriatr Soc 2020 Jul 14. Epub 2020 Jul 14.

Journal of the American Geriatrics Society, USA.

J Gerontol A Biol Sci Med Sci 2020 Jul 14. Epub 2020 Jul 14.

Executive Editor, Journal of the American Geriatrics Society.

Radiology 2020 Jul 14:200281. Epub 2020 Jul 14.

From the Department of Radiology and Research Institute of Radiology (D.W.K., S.S.L., J.H.K., H.J.K., J.H.B.), Department of Clinical Epidemiology and Biostatistics (S.O.K.), Department of Oncology (C.Y., K.P.K.), and Department of Surgery (K.B.S., S.C.K.), University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43-Gil, Songpa-Gu Seoul, Seoul 138-736, Republic of Korea.

Background No preoperative model is available for predicting postsurgical prognosis of patients with resectable pancreatic ductal adenocarcinoma (PDAC). Purpose To develop and validate a preoperative risk scoring system using clinical and CT variables to predict recurrence-free survival (RFS) after upfront surgery in patients with resectable PDAC. Materials and Methods In this retrospective study, consecutive patients with resectable PDAC underwent upfront surgery from January 2014 to December 2015 (development set) and from January 2016 to January 2017 (test set). Read More

Clin Exp Rheumatol 2020 Jun 30. Epub 2020 Jun 30.

Department of Immunology, College of Basic Medical Science, Dalian Medical University, Dalian; Department of Rheumatology, Affiliated Hospital of Nantong University, China.

Objectives: Initial studies investigating peripheral levels of leptin and soluble leptin receptor (LepR) in systemic lupus erythematosus (SLE) patients have generated a number of controversial results. Thus, we conducted a meta-analysis to evaluate the circulating leptin level, soluble LepR level and related gene polymorphism in SLE patients.

Methods: We performed a meta-analysis comparing the circulating leptin level, LepR level and their gene polymorphism in patients with SLE to controls, and evaluate the relationship between leptin levels, LepR levels and SLE disease activity. Read More

Am J Trop Med Hyg 2020 Jul 13. Epub 2020 Jul 13.

Pan American Center for Foot-and-Mouth Disease and Veterinary Public Health, Pan American Health Organization/World Health Organization (PANAFTOSA-PAHOWHO).

Control of Rabies as a Victim of Its Own Success: Perception of Risk within a Latin American Population. Read More

Res Aging 2020 Jul 14:164027520937477. Epub 2020 Jul 14.

Syracuse University, NY, USA.

This research examined whether perceived receipt of filial piety from adult children and ethnic community engagement-two major ethnocultural resources-were associated with psychological wellbeing of older Chinese American immigrants. Analyses used data from the PINE study, a sample of older Chinese adults in Chicago. Tobit regression revealed that elders who received more filial piety and visited community centers experienced less loneliness and depression than their counterparts did. Read More

Biol Res Nurs 2020 Jul 14:1099800420941074. Epub 2020 Jul 14.

Department of Nursing, Health Sciences Faculty, University of Granada (UGR), Granada, Spain.

Hypertension has been established as a common health condition in young people. Most studies have focused on the impact of body mass index (BMI), but the relationships between body composition parameters and blood pressure in Palestinian children has not previously been investigated. We aimed to analyze the prevalence of overweight/obesity and elevated blood pressure/hypertension and investigate the associations among obesity-related parameters, including anthropometric and body composition markers and blood pressure levels in a population of 971 Palestinian school children (50% girls; mean age 10. Read More

Dev Psychobiol 2020 Jul 13. Epub 2020 Jul 13.

Arizona State University, Tempe, AZ, USA.

According to polyvagal theory, rapid modulation of the vagal brake develops early in infancy and supports social interactions. Despite being viewed as a dynamic system, researchers typically assess vagal regulation using global measures of respiratory sinus arrhythmia (RSA; an index of vagal tone). This study sought to capture the dynamic property of RSA and evaluate individual differences in within-infant RSA responsivity during mother-infant interaction. Read More

J Anim Ecol 2020 Jul 13. Epub 2020 Jul 13.

Department of Biological Sciences, Boise State University, Boise, ID, USA.

Dispersal is a critical process influencing population dynamics and responses to global change. Long-distance dispersal (LDD) can be especially important for gene flow and adaptability, although little is known about the factors influencing LDD because studying large-scale movements is challenging and LDD tends to be observed less frequently than shorter-distance dispersal (SDD). We sought to understand patterns of natal dispersal at a large scale, specifically aiming to understand the relative frequency of LDD compared to SDD and correlates of dispersal distances. Read More

J Am Geriatr Soc 2020 Jul 13. Epub 2020 Jul 13.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

To prepare for the increasing numbers of older adults undergoing surgery, the American College of Surgeons (ACS) has recently launched the Geriatric Surgery Verification Program with the goal of encouraging the creation of centers of geriatric surgery. Meanwhile, the Society for Perioperative Assessment and Quality Improvement (SPAQI) has published recommendations for the preoperative management of frailty, which state that teams should actively screen for frailty before surgery and that pathways, including geriatric comanagement, shared decision-making, and multimodal prehabilitation, should be embedded in routine care to help improve patient outcomes. Both SPAQI and the ACS advocate for a multidisciplinary approach to improve the value of care for older adults undergoing surgery. Read More

J Racial Ethn Health Disparities 2020 Jul 13. Epub 2020 Jul 13.

University of Houston Graduate College of Social Work, Houston, TX, USA.

In recent years, significant policy changes focused on immigrants migrating through the southern United States border have been implemented. To determine if there was an association between time since immigration and increases in negative mental health symptomology, 249 Mexican-American immigrants ages 18-65 were field recruited to participate in a survey exploring their physical and mental health. Results indicate that inconsistent with the Hispanic Health Paradox, the psychological health of immigrants arriving since 2015 was significantly worse than that of more established immigrants. Read More

J Community Health 2020 Jul 13. Epub 2020 Jul 13.

Division of Infectious Diseases, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

The outbreak of the novel coronavirus disease in 2019 (COVID-19) caused a plethora of challenges worldwide and tested healthcare systems across the six continents. Lebanon had recently faced harsh political and economic crises. We aim to describe the effect of COVID-19 on an already crisis-stricken country. Read More

J Psychopathol Behav Assess 2020 Mar 10;42:93-100. Epub 2019 Dec 10.

Department of Psychological and Brain Sciences, Boston University, Boston, Massachusetts, USA.

Background: People differ in their affective styles, which refers to habitual use of emotion regulation (ER) strategies. Previous research has shown that mental health is associated with an individual's adaptive flexibility of emotion regulation strategies rather than any one particular ER strategy.

Methods: The present study employed a person-centered approach using latent profile analyses to distinguish patients with generalized anxiety disorder based on their responses on an affective styles measure. Read More

Nat Methods 2020 Jul 13. Epub 2020 Jul 13.

Department of Neurobiology, Stanford University, Stanford, CA, USA.

Sensitive detection of two biological events in vivo has long been a goal in bioluminescence imaging. Antares, a fusion of the luciferase NanoLuc to the orange fluorescent protein CyOFP, has emerged as a bright bioluminescent reporter with orthogonal substrate specificity to firefly luciferase (FLuc) and its derivatives such as AkaLuc. However, the brightness of Antares in mice is limited by the poor solubility and bioavailability of the NanoLuc substrate furimazine. Read More

Nat Neurosci 2020 Jul 13. Epub 2020 Jul 13.

Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Cerebellar dysfunction has been demonstrated in autism spectrum disorders (ASDs); however, the circuits underlying cerebellar contributions to ASD-relevant behaviors remain unknown. In this study, we demonstrated functional connectivity between the cerebellum and the medial prefrontal cortex (mPFC) in mice; showed that the mPFC mediates cerebellum-regulated social and repetitive/inflexible behaviors; and showed disruptions in connectivity between these regions in multiple mouse models of ASD-linked genes and in individuals with ASD. We delineated a circuit from cerebellar cortical areas Right crus 1 (Rcrus1) and posterior vermis through the cerebellar nuclei and ventromedial thalamus and culminating in the mPFC. Read More

Sci Rep 2020 Jul 13;10(1):11529. Epub 2020 Jul 13.

Department of Physics, The American University in Cairo, Cairo, 11835, Egypt.

Despite that Hyperbolic Metamaterial (HMM) has demonstrated sub-wavelength focusing inside of it, sub-wavelength imaging in free space of HMM is rarely introduced. The decay of hyperbolic momentum space outside the hyperbolic medium has hindered the realization of sub-wavelengh focusing in the near field of HMM. Furthermore, manipulating the negatively refracted waves exiting the HMM have addressed another major obstacle to realize free space sub-wavelength focusing. Read More

J Immunother Cancer 2020 Jul;8(2)

Department of Genitourinary Medical Oncology, MD Anderson Cancer Center, University of Texas, Houston, Texas, USA.

Background: The extent to which response and survival benefits with immunotherapy-based regimens persist informs optimal first-line treatment options. We provide long-term follow-up in patients with advanced renal cell carcinoma (aRCC) receiving first-line nivolumab plus ipilimumab (NIVO+IPI) versus sunitinib (SUN) in the phase 3 CheckMate 214 trial. Survival, response, and safety outcomes with NIVO+IPI versus SUN were assessed after a minimum of 42 months of follow-up. Read More

Neurology 2020 Jul 13. Epub 2020 Jul 13.

From Harvard Medical School (E.A., S.S.M., S.S.C., M.T.B., M.B.W.); Department of Neurology (E.A., S.S.C., M.T.B., M.B.W.), Massachusetts General Hospital, Boston; Department of Neurology (E.A.), University of California, San Francisco; and Computer Science and Artificial Intelligence Laboratory (E.A., S.P.) and Department of Electrical Engineering and Computer Science (M.M.G., W.-H.W.), Massachusetts Institute of Technology, Cambridge.

Objective: To determine cost-effectiveness parameters for EEG monitoring in cardiac arrest prognostication.

Methods: We conducted a cost-effectiveness analysis to estimate the cost per quality-adjusted life-year (QALY) gained by adding continuous EEG monitoring to standard cardiac arrest prognostication using the American Academy of Neurology Practice Parameter (AANPP) decision algorithm: neurologic examination, somatosensory evoked potentials, and neuron-specific enolase. We explored lifetime cost-effectiveness in a closed system that incorporates revenue back into the medical system (return) from payers who survive a cardiac arrest with good outcome and contribute to the health system during the remaining years of life. Read More

Ann Fam Med 2020 Jul;18(4):380-382

American Board of Family Medicine.

Ann Fam Med 2020 Jul;18(4):370-373

American Board of Family Medicine, Lexington, Kentucky.

Purpose: The purpose of this study was to characterize graduates of family medicine (FM) residencies from 1994 to 2017 and determine whether they continue to practice family medicine after residency.

Method: We sampled physicians who completed FM residency training from 1994-2017 using 2017 American Medical Association (AMA) Physician Masterfile linked with administrative files of the American Board of Family Medicine (ABFM). The main outcomes measured were characteristics of FM residency graduates, including medical degree type (Doctor of Medicine, MD vs Doctor of Osteopathic Medicine, DO), international medical school graduates (IMGs) vs US graduates, sex, ABFM certification status, and self-designated primary specialty. Read More