Am J Physiol Endocrinol Metab 2017 Dec 5:ajpendo.00353.2017. Epub 2017 Dec 5.
University of Birmingham.
Skeletal muscle is an endocrine organ that secretes a variety of compounds including proteins (myokines), metabolites, microRNAs (miRNAs) and exosomes. Many of which are regulated by exercise and play important roles in endocrine signaling. Inter-organ communication via muscle-secreted factors therefore provides a novel area for investigation and implicates the importance of skeletal muscle in the pathophysiology of metabolic diseases such as type 2 diabetes (T2D). Read More