333,064 results match your criteria American Journal of Pharmaceutical Education [Journal]


A Farewell to Falsity: Shifting Standards in Medicare Fraud Enforcement.

Authors:
Isaac D Buck

Seton Hall Law Rev 2019 ;49(1):1-51

University of Tennessee College of Law.

For the better part of a decade, Americans have had a front-row seat to a fervent and turbulent debate over the future of their health care system. The passage of the Patient Protection and Affordable Care Act of 2010 (ACA), the most comprehensive health reform effort since the mid-1960s, ushered in a new era in health law and policy, granting millions of Americans access to health care. After multiple legal challenges and congressional efforts that ultimately failed to slay the law, the ACA had become entrenched by the end of the Obama administration, even though pieces of the law had failed to work exactly as planned. Read More

View Article
January 2019

Urinary metals and leukocyte telomere length in American Indian communities: The Strong Heart and the Strong Heart Family Study.

Environ Pollut 2018 Dec 5;246:311-318. Epub 2018 Dec 5.

Area of Cardiometabolic and Renal Risk, Biomedical Research Institute Hospital Clinic of Valencia (INCLIVA), Valencia, Spain; Department of Environmental Health and Engineering, Johns Hopkins University, Baltimore, MD, USA; Department of Chronic Diseases Epidemiology, National Center for Epidemiology, Carlos III Health Institutes, Madrid, Spain.

Introduction: While several mechanisms may explain metal-related health effects, the exact cellular processes are not fully understood. We evaluated the association between leukocyte telomere length (LTL) and urine arsenic (ΣAs), cadmium (Cd) and tungsten (W) exposure in the Strong Heart Study (SHS, N = 1702) and in the Strong Heart Family Study (SHFS, N = 1793).

Methods: Urine metal concentrations were measured using ICP-MS. Read More

View Article
December 2018

Comparison of International Systemic Adverse Reactions due to Allergen Immunotherapy.

J Allergy Clin Immunol Pract 2018 Dec 14. Epub 2018 Dec 14.

Section of Allergy and Clinical Immunology, Imperial College London, National Heart and Lung Institute, Royal Brompton Hospital, London, UK.

Background: Several classifications of systemic adverse reactions (SAR) during allergen immunotherapy (AIT) have been proposed but the comparison of their usefulness in daily clinical practice is lacking.

Objective: The present post hoc analysis was aimed to investigate the practicality of the most relevant international classifications proposed by the European Academy of Allergology and Clinical Immunology (EAACI), the American Academy of Asthma, Allergology and Clinical Immunology /American College of Allergy, Asthma and Immunology (AAAACI/ACAAI), and the World Allergy Organization (WAO) using data provided by the longitudinal European Survey on Adverse Systemic Reactions in Allergen Immunotherapy (EASSI) based on daily clinical practice in 3 countries in Europe.

Methods: One hundred and nine SAR over 4363 AIT courses were classified as mild (n=78, 71. Read More

View Article
December 2018
1 Read

Insurance Approval for Proton Beam Therapy and its Impact on Delays in Treatment.

Int J Radiat Oncol Biol Phys 2018 Dec 14. Epub 2018 Dec 14.

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ. Electronic address:

Purpose: Prior authorization (PA) has been widely implemented for proton beam therapy (PBT). We sought to determine the association between PA determination and patient characteristics, practice guidelines, and potential treatment delays.

Methods And Materials: A single-institution retrospective analysis was performed of all patients considered for PBT between 2015 and 2018 at a National Cancer Institute-designated Comprehensive Cancer Center. Read More

View Article
December 2018

Associations of urban greenness with asthma and respiratory symptoms in Mexican American children.

Ann Allergy Asthma Immunol 2018 Dec 14. Epub 2018 Dec 14.

Professor, Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago.

View Article
December 2018

Safety of robotic-assisted gynecologic surgery and early hospital discharge in elderly patients.

Am J Obstet Gynecol 2018 Dec 14. Epub 2018 Dec 14.

New York University Langone Medical Center. Electronic address:

Background: A minimally invasive surgical approach has proven to decrease peri- and post-operative complications and shorten duration of hospital stay, however there is limited data evaluating the safety of robotic-assisted surgery and early hospital discharge in the elderly population. As age is a well-known, independent risk factor for peri-operative morbidity and gynecologists treat many elderly patients, this is an important area of study.

Objective: To evaluate discharge timing and surgical outcomes in elderly compared to younger patients undergoing robotic-assisted gynecologic surgery. Read More

View Article
December 2018
1 Read

Capturing biochemical diversity in cassava (Manihot esculenta Crantz) through the application of metabolite profiling.

J Agric Food Chem 2018 Dec 17. Epub 2018 Dec 17.

Cassava (Manihot esculenta Crantz) is the predominant staple food in Sub-Saharan African (SSA) and an industrial crop in South East Asia. Despite focused breeding efforts for increased yield, resistance and nutritional value, cassava breeding has not advanced at the same rapidity as other staple crops. In the present study, metabolomic techniques were developed and implemented to characterize the chemotypes of selected cassava accessions and assess potential resources for the breeding program. Read More

View Article
December 2018

Guidelines Versus Guidelines.

Ann Intern Med 2018 Dec;169(12):896-897

American Diabetes Association, Arlington, Virginia (W.T.C.).

View Article
December 2018

Correction: Allelic variation of vernalization and photoperiod response genes in a diverse set of North American high latitude winter wheat genotypes.

Authors:

PLoS One 2018 17;13(12):e0209543. Epub 2018 Dec 17.

[This corrects the article DOI: 10.1371/journal.pone. Read More

View Article
December 2018

An international analysis of the price and affordability of beer.

PLoS One 2018 17;13(12):e0208831. Epub 2018 Dec 17.

Economics of Tobacco Control Project, Southern African Labour and Development Research Unit, University of Cape Town, Cape Town, South Africa.

Aims: To apply methods for measuring the affordability of beer in a large cross section of countries, and to investigate trends in affordability of beer over time.

Methods: We use the Relative Income Price (RIP), which uses per capita GDP, to measure the affordability of beer in up to 92 countries from 1990 to 2016 (69 countries were included in 1990, however the survey has since grown to include 92 countries). In addition to affordability, we also investigate trends in the price of beer. Read More

View Article
December 2018
1 Read

Peer-assisted learning after onsite, low-dose, high-frequency training and practice on simulators to prevent and treat postpartum hemorrhage and neonatal asphyxia: A pragmatic trial in 12 districts in Uganda.

PLoS One 2018 17;13(12):e0207909. Epub 2018 Dec 17.

Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

An urgent need exists to improve and maintain intrapartum skills of providers in sub-Saharan Africa. Peer-assisted learning may address this need, but few rigorous evaluations have been conducted in real-world settings. A pragmatic, cluster-randomized trial in 12 Ugandan districts provided facility-based, team training for prevention and management of postpartum hemorrhage and birth asphyxia at 125 facilities. Read More

View Article
December 2018

Contribution of High School Sport Participation to Young Adult Bone Strength.

Med Sci Sports Exerc 2018 Dec 14. Epub 2018 Dec 14.

Department of Preventative and Community Dentistry, College of Dentistry, University of Iowa, Iowa City, IA.

Introduction: Nearly 8 million American adolescents participate in sports. Participation declines in young adulthood.

Purpose: This study assessed longitudinal effects of high school sport participation and muscle power on young adult bone strength. Read More

View Article
December 2018

Integrative Medicine in Plastic Surgery: A Systematic Review of Our Literature.

Ann Plast Surg 2018 Dec 13. Epub 2018 Dec 13.

Division of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

Background: Surveys have reported that as high as 80% of plastic surgery patients utilize integrative medicine approaches including natural products (NPs) and mind-body practices (MBPs). Little is known regarding the evidence of benefit of these integrative therapies specifically in a plastic surgery patient population.

Methods: We conducted a systematic review of studies in MEDLINE, PubMed, and EMBASE (inception through December 2016) evaluating integrative medicine among plastic surgery patients. Read More

View Article
December 2018

From A to D: A Unique Case Report of Recovery after Longitudinal Myelitis Related to Lupus.

Am J Phys Med Rehabil 2018 Dec 14. Epub 2018 Dec 14.

HealthPartners Neuroscience Center, St. Paul, MN, USA.

Longitudinal myelitis secondary to an acute flare of systemic lupus erythematosus (SLE) has been reported in the literature. There have been few published cases of complete functional recovery in patients with systemic lupus erythematosus related longitudinal myelitis (SLE-LM). Of those cases, none have described in detail the rehabilitation course of treatment. Read More

View Article
December 2018
1 Read

Under the face mask: Racial-ethnic minority student-athletes and mental health use.

J Am Coll Health 2018 Dec 17:1-7. Epub 2018 Dec 17.

a Arizona State University , Counseling Psychology , Tempe , AZ , USA.

Objective: To investigate racial-ethnic minority student-athletes' (REMSA) symptoms of distress (mental health need), mental health use (usage rate), and factors that influence mental health usage.

Participants: There were 241 varsity athletes (African American = 108, Latinos = 66, Asian American= 67) from the American College Health Association Fall 2015 data set.

Results: Seventy-eight percent of REMSA reported some form of mental health need and only 11% of these athletes in need reported using mental health services in the past year. Read More

View Article
December 2018

Morphology and evolution of the wing bullae in South American Leptophlebiidae (Ephemeroptera).

J Morphol 2019 Jan;280(1):95-102

Instituto de Biodiversidad Neotropical (IBN), UNT-CONICET, Cátedra de Biología General, Facultad de Ciencias Naturales, Universidad Nacional de Tucumán, Tucumán, Argentina.

Insects were the first animals to take to the skies, and have been flying for over 320 million years. The order Ephemeroptera is, or at least is part of, the most early-diverging lineage of extant winged insects. The extant species present a very short adult life span, mainly dedicated to reproduction and dispersal of eggs. Read More

View Article
January 2019

Evaluation of management in North American zoos to enhance breeding success of the fishing cat (Prionailurus viverrinus) ex situ population.

Zoo Biol 2018 Dec 17. Epub 2018 Dec 17.

Department of Environmental Science and Policy, George Mason University, Fairfax, Virginia.

The ex situ population of fishing cats (Prionailurus viverrinus) face many challenges to its sustainability such as mate incompatibility, low founder numbers and disease prevalence. The North American population was monitored for a three-year period during institutional transfers and breeding introductions. In total, 26 fishing cats, including 15 different breeding pairs were monitored during 20 transfers. Read More

View Article
December 2018

Kocuria tytonis sp. nov., isolated from the uropygial gland of an American barn owl (Tyto furcata).

Int J Syst Evol Microbiol 2018 Dec 17. Epub 2018 Dec 17.

1​Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, INF 364, 69120 Heidelberg, Germany.

Avian uropygial glands have received increasing attention in recent years, but little is known about micro-organisms in uropygial glands. In this study, we isolated a strain of Gram-stain-positive, non-motile, non-spore-forming cocci, designated 442, from the uropygial gland of an American barn owl (Tyto furcata) and characterized it using a polyphasic approach. 16S rRNA gene sequence analysis placed the isolate in the genus Kocuria. Read More

View Article
December 2018

Health Care Utilization and Cost Associated with Biologic Treatment Patterns Among Patients with Moderate to Severe Psoriasis: Analyses from a Large U.S. Claims Database.

J Manag Care Spec Pharm 2018 Dec 17:1-11. Epub 2018 Dec 17.

3 Health Economics & Outcomes Research, Novartis Pharmaceuticals Corporation, East Hanover, New Jersey.

Background: Discontinuation or switching of biologic treatment among patients with psoriasis imposes a great economic burden.

Objective: To assess the health care utilization and costs associated with nonswitchers, switchers, and discontinuers of biologics among patients with moderate to severe psoriasis.

Methods: Patients aged ≥ 18 years with ≥ 1 pharmacy claim for a biologic (adalimumab, etanercept, infliximab, and ustekinumab) between January 1, 2012, and June 30, 2015 (identification period), were identified in the Truven Health Analytics MarketScan Commercial and Medicare Supplemental databases. Read More

View Article
December 2018

Collective ethnic-racial identity and health outcomes among African American youth: Examination of promotive and protective effects.

Cultur Divers Ethnic Minor Psychol 2018 Dec 17. Epub 2018 Dec 17.

Community Evaluation and Research Collaborative, Michigan State University.

Objectives: Racial discrimination is associated with numerous negative health outcomes, including increased risk for depression and anxiety symptoms and substance use. Positive affect toward of one's ethnic or racial group (i.e. Read More

View Article
December 2018

The socioecological psychology of upward social mobility.

Am Psychol 2018 Dec 17. Epub 2018 Dec 17.

Department of Psychology, University of Virginia.

Intergenerational upward economic mobility-the opportunity for children from poorer households to pull themselves up the economic ladder in adulthood-is a hallmark of a just society. In the United States, there are large regional differences in upward social mobility. The present research examined why it is easier to get ahead in some cities and harder in others. Read More

View Article
December 2018

Description and characterization of a hair coat disorder in schipperkes.

Vet Dermatol 2018 Dec 17. Epub 2018 Dec 17.

Department of Biomedical and Diagnostic Sciences, UT College of Veterinary Medicine, University of Tennessee, 2407 River Drive, Knoxville, TN, 37996, USA.

Background: Schipperkes develop bilaterally symmetrical alopecia preceded by lightening of the hair coat not associated with systemic clinical signs. The alopecia is presumptively diagnosed as Alopecia X but has never been investigated.

Hypothesis/objectives: The purpose of this study was to describe clinical features, histopathological and laboratory abnormalities associated with symmetrical, noninflammatory alopecia in schipperkes. Read More

View Article
December 2018
1 Read

Characterization and implications of solids associated with hydraulic fracturing flowback and produced water from the Duvernay Formation, Alberta, Canada.

Environ Sci Process Impacts 2018 Dec 17. Epub 2018 Dec 17.

Department of Earth and Atmospheric Sciences, University of Alberta, Edmonton, AB T6G 2E3, Canada.

Public concern is heightened around flowback and produced water (FPW) generated by the hydraulic fracturing process. FPW is a complex mix of organic and inorganic solutes derived from both the injected hydraulic fracturing fluid and interactions with the subsurface lithology. Few studies to date have systematically investigated the composition of FPW or its individual components. Read More

View Article
December 2018
1 Read

Management of Children With Diabetes in the School Setting.

Authors:

Diabetes Educ 2018 Dec 17:145721718820943. Epub 2018 Dec 17.

Diabetes educators are well positioned to help optimize care of the student with diabetes within the school setting. Read More

View Article
December 2018
1 Read

Cultural Perspectives on Tobacco Use and Cessation Among Chinese American Immigrants: A Community-Engaged Qualitative Study.

J Transcult Nurs 2018 Dec 17:1043659618817583. Epub 2018 Dec 17.

3 Chinese Consolidated Benevolent Association of New England, Boston, MA, USA.

Introduction: Tobacco use is a preventable cause of death among ethnic minorities. Chinese Americans have high smoking rates and underutilize evidence-based cessation therapies. Community members' perspectives on tobacco use and cessation may help bridge treatment gaps and ensure that cessation approaches are aligned with cultural values. Read More

View Article
December 2018

The Role of the Diabetes Educator in Diabetes Formulary and Medical Device Decisions.

Authors:

Diabetes Educ 2018 Dec 17:145721718820942. Epub 2018 Dec 17.

It is the position of the American Association of Diabetes Educators that diabetes educators should be included as expert consultants for formulary decisions regarding diabetes medications and medical devices. Read More

View Article
December 2018

Role of the Diabetes Educator in Inpatient Diabetes Management.

Authors:

Diabetes Educ 2018 Dec 17:145721718820944. Epub 2018 Dec 17.

It is the position of American Association of Diabetes Educators (AADE) that all inpatient interdisciplinary teams include a diabetes educator to lead or support improvement efforts that affect patients hospitalized with diabetes or hyperglycemia. This not only encompasses patient and family education but education of interdisciplinary team members and achievement of diabetes-related organizational quality metrics and performance outcomes. Read More

View Article
December 2018
1 Read

They Are Coming Home: The Effect of Trauma-Related Cognitions on Vocational Readiness of Incarcerated Women.

J Interpers Violence 2018 Dec 17:886260518817776. Epub 2018 Dec 17.

1 University of South Carolina, Columbia, USA.

The prevalence of trauma in the lives of incarcerated women has been well-documented. Yet, few studies have included trauma-related cognitions, a common response to interpersonal trauma, in their analyses. The purpose of this study was to examine the relationship between trauma (pre-incarceration trauma [PIT] and incarceration-based trauma [IBT]), trauma-related cognitions [TRC] (i. Read More

View Article
December 2018

Pilot RCT of a social media parenting intervention for postpartum mothers with depression symptoms.

J Reprod Infant Psychol 2018 Dec 17:1-12. Epub 2018 Dec 17.

b Policylab: Center to Bridge Research Practice, & Policy , The Children's Hospital of Philadelphia, Roberts Center for Pediatric Research , Philadelphia , PA , USA.

Objective: This pilot study describes the adaptation of a parenting group intervention for social media, and examines the feasibility, acceptability and initial outcomes of the adapted intervention for mothers with postpartum depression symptoms.

Background: Postpartum depression can negatively affect parenting and the parent-infant relationship. Mothers with postpartum depression symptoms experience barriers to access in-person parenting interventions. Read More

View Article
December 2018

Moving Toward Openness: Blackfeet Indians' Perception Changes Regarding Talking About End of Life.

Am J Hosp Palliat Care 2018 Dec 16:1049909118818255. Epub 2018 Dec 16.

2 Eagle Shield Center, Blackfeet Nation, Browning, MT, USA.

This study was conducted to examine cultural appropriateness and readiness for the Blackfeet people in the United States talking about end of life. In the past, a taboo perception of Blackfeet traditional belief in end-of-life discussion was identified as a core barrier for hospice use. However, a recent anecdotal increase in hospice interest triggered the research team to investigate community-wide interest as well as traditional appropriateness of hospice introduction. Read More

View Article
December 2018

Tissue Engineering for the Temporomandibular Joint.

Adv Healthc Mater 2018 Dec 17:e1801236. Epub 2018 Dec 17.

Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, 52242, USA.

Tissue engineering potentially offers new treatments for disorders of the temporomandibular joint which frequently afflict patients. Damage or disease in this area adversely affects masticatory function and speaking, reducing patients' quality of life. Effective treatment options for patients suffering from severe temporomandibular joint disorders are in high demand because surgical options are restricted to removal of damaged tissue or complete replacement of the joint with prosthetics. Read More

View Article
December 2018

Risk factors and prognostic implications of aspiration pneumonia in older hip fracture patients: A multicenter retrospective analysis.

Geriatr Gerontol Int 2018 Dec 16. Epub 2018 Dec 16.

Department of Orthopaedic Surgery, CHA Bundang Medical Center, CHA University, Seongnam, Korea.

Aim: The present study aimed to investigate the risk factors and prognostic implications of aspiration pneumonia in older hip fracture patients.

Methods: A total of 394 female and 125 male hip fracture patients aged ≥60 years who underwent surgery between 2015 and 2018 were retrospectively analyzed. To identify risk factors of aspiration pneumonia, demographic factors, the American Society of Anesthesiologists classification, past medical history, known risk factors of aspiration and factors associated with surgery were compared between the aspiration pneumonia group and the control group. Read More

View Article
December 2018

Concordance and Reproducibility of Melanoma Staging According to the 7th vs 8th Edition of the .

JAMA Netw Open 2018 May;1(1)

Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles (Elmore); Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia (Elder); Department of Pathology, Institut Curie, Paris, France (Barnhill); Paris Sciences and Lettres Research University, Paris, France (Barnhill); Faculty of Medicine, University of Paris Descartes, Paris, France (Barnhill); Pathology Associates, Clovis, California (Knezevich); Program in Biostatistics and Biomathematics, Fred Hutchinson Cancer Research Center, Seattle, Washington (Longton, Pepe); Department of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire (Titus); Department of Pediatrics, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire (Titus); Norris Cotton Cancer Center, Lebanon, New Hampshire (Titus); Center for Dermatoepidemiology, Providence Veterans Affair Medical Center, Providence, Rhode Island (Weinstock); Department of Dermatology, Brown University, Providence, Rhode Island (Weinstock); Department of Epidemiology, Brown University, Providence, Rhode Island (Weinstock); Department of Medical Informatics and Clinical Epidemiology, School of Medicine, Oregon Health and Science University, Portland (Nelson); Department of Medicine, School of Medicine, Oregon Health and Science University, Portland (Nelson); Department of Medicine, University of Washington School of Medicine, Seattle (Reisch, Radick, Piepkorn); Dermatopathology Northwest, Bellevue, Washington (Piepkorn).

Importance: The recently updated American Joint Committee on Cancer (AJCC) classification of cancer staging, the , 8th edition (), includes revisions to definitions of T1a vs T1b or greater. The Melanoma Pathology Study database affords a comparison,of pathologists' concordance and reproducibility in the microstaging of melanoma according to both the existing 7th edition ) and the new .

Objective: To compare and to examine whether changes to the definitions of T1a and T1b or greater are associated with changes in concordance and reproducibility. Read More

View Article
May 2018
1 Read

The Association of Fasting Glucose, Insulin, and C-Peptide, with 19-Year Incidence of Coronary Heart Disease in Older Japanese-American Men; the Honolulu Heart Program.

Geriatrics (Basel) 2018 22;3(2). Epub 2018 Apr 22.

Department of Geriatric Medicine, John A. Burns School of Medicine, University of Hawaii, Hale Pulama Mau, 9th Floor, 347 N. Kuakini St, Honolulu, Hawaii, 96817, USA.

The role of fasting glucose, insulin levels, and C-peptide in coronary heart disease (CHD) in non-diabetic individuals remains uncertain. We examined the association between fasting glucose, insulin and C-peptide with the long-term incidence of CHD in Japanese-American men. In 1980-1982, from a random sample of the Honolulu Heart Program men ( = 1378), aged 61-81 years, data on several CHD and metabolic risk factors were obtained to examine the relation of fasting glucose, insulin and C-peptide to 19-year CHD incidence. Read More

View Article

Death in patients with adaptive servo-ventilation for sleep apnea and no specific SERVE-HF profile: A case series study.

Respir Med Case Rep 2019 26;26:68-72. Epub 2018 Nov 26.

Haut-Leveque Cardiology Hospital, Pessac, France.

Purpose: The SERVE-HF study reported a risk of cardiovascular death associated with adaptive servo-ventilation (ASV) for central sleep apnea in patients with chronic heart failure with reduced left ventricular ejection fraction (LVEF). Therefore, we adopted in May 2015 a safety procedure in our 32 patients with ASV since 2006. It led to ASV removal in four patients due to ≤45% LVEF. Read More

View Article
November 2018

Bibliometric Study of Obstetrics Articles Published in the Journal of the American Medical Association, 1997-2016.

Cureus 2018 Oct 13;10(10):e3448. Epub 2018 Oct 13.

Internal Medicine, Medical Governance Research Institute, Tokyo, JPN.

Introduction A recent increase in cases of advanced maternal age in the US has been partly associated with a higher incidence of pregnancy-related complications and infertility. However, little is known on how such social changes may have influenced obstetrics articles published in high-impact medical journals subscribed by diverse physicians. The objective of this study is to elucidate the presence and trend of obstetrics investigations in high-profile medical journals. Read More

View Article
October 2018

Cognitive Errors and Risks Associated with Provider Handoffs.

Cureus 2018 Oct 12;10(10):e3442. Epub 2018 Oct 12.

Emergency Medicine, Florida Hospital, Orlando, USA.

The emergency department is a challenging environment to practice medicine, primarily due to the pace and logistics of practicing emergency medicine. Cognitive errors and provider handoffs can lead to poor patient outcomes. By acknowledging and addressing cognitive errors, including premature closure, anchoring, and diagnosis momentum, we can potentially improve patient care. Read More

View Article
October 2018
1 Read

Effects of body protection vests and experience levels in prevention of equestrian injuries.

BMJ Open Sport Exerc Med 2018 16;4(1):e000426. Epub 2018 Nov 16.

United States Pony Clubs, Lexington, Kentucky, USA.

Objectives: To investigate the risk reduction and benefit of wearing body protection/safety vests in equestrian sports.

Methods: A comparison of equestrians wearing body protective vests and those not wearing vests was performed using incident report data of 718 participants in the United States Pony Clubs during 2011-2017. Data obtained included age, gender, certification level of member, type of activity, description of incident, description of injuries, what protective equipment was worn and other possible contributing factors. Read More

View Article
November 2018
1 Read

Impact of smoking on patient outcomes after arthroscopic rotator cuff repair.

BMJ Open Sport Exerc Med 2018 21;4(1):e000416. Epub 2018 Nov 21.

Department of Orthopedic Surgery, University of Michigan, Ann Arbor, Michigan, USA.

Background: Cigarette smoking may adversely affect rotator cuff tear pathogenesis and healing. However, the impact of cigarette smoking on outcomes after arthroscopic rotator cuff repair is relatively unknown.

Patients And Methods: A cohort of 126 patients who underwent arthroscopic rotator cuff repair with minimum 2 years follow-up were retrospectively identified from our institutional database. Read More

View Article
November 2018

Skin as an immune organ and clinical applications of skin-based immunotherapy.

World Allergy Organ J 2018 7;11(1):38. Epub 2018 Dec 7.

5Universidad Autónoma del Estado de Hidalgo, Pachuca, Hidalgo Mexico.

Background: The prevalence of food allergy is increasing, and allergen avoidance continues to be the main standard of care. There is a critical need for safe and effective forms of immunotherapy for patients with food allergy as well as other allergic diseases.

Findings: The skin is a multifunctional organ with unique immunologic properties, making it a favorable administration route for allergen-specific immunotherapy. Read More

View Article
December 2018

Letter to the editors regarding the paper: Prognostic factors in HIV-positive patients with non-Hodgkin lymphoma: a Peruvian experience.

Infect Agent Cancer 2018 11;13:39. Epub 2018 Dec 11.

1Escuela de Medicina, Facultad de Ciencias de la Salud, Universidad Peruana de Ciencias Aplicadas, 2 Alameda San Marcos Avenue, Chorrillos, 15067 Lima, Peru.

Non-Hodgkin Lymphoma (NHL) is a neoplasm associated with a group of malignancies called AIDs-Defining Malignancies (ADMs) in Human-Immunodeficiency Virus (HIV) -patients. Similar to the case of NHL in Latin America, particularly in Peru, the amount of research done on others ADMs is limited, especially in the case of Kaposi's Sarcoma (KS). Prior investigations have talked about the great potential risk that represents this illness in latin american population, but topics as prognosis factors are yet to be well defined. Read More

View Article
December 2018

Comparative Transcriptome and iTRAQ Proteome Analyses Reveal the Mechanisms of Diapause in Ashmead (Hymenoptera: Aphidiidae).

Front Physiol 2018 30;9:1697. Epub 2018 Nov 30.

Key Laboratory of Integrated Pest Management in Crops, Ministry of Agriculture, Sino-American Biological Control Laboratory, USDA-ARS/Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China.

Ashmead (Hymenoptera: Aphidiidae) is a solitary endoparasitoid used in the biological control of various aphids. Diapause plays an important role in the successful production and deployment of . Diapause can effectively extend the shelf life of biological control agents and solve several practical production problems like long production cycles, short retention periods, and discontinuities between supply and demand. Read More

View Article
November 2018

Identification and characterization of microsatellite loci in West Atlantic sea cucumber (Selenka 1867).

J Genet 2018 Dec;97(5):1363-1369

Faculdade de Veterinária, Universidade Estadual do Ceará, Pós-graduação em Ciências Veterinárias, Av. Dr. Silas Munguba 1700, Fortaleza, CE 60714-903, Brazil.

The sea cucumber has become the subject of intense and unregulated fishing in northeastern Brazil due to their growing demand in Asian market. However, there is little knowledge about the dynamics and genetics of wild populations on the South American coast. In this study, we present the first set of microsatellite markers, identified and characterized using Illumina paired-end reads of whole genome shotgun sequencing. Read More

View Article
December 2018

Genetic diversity and cultivar variants in the NCGR cranberry ( Aiton) collection.

J Genet 2018 Dec;97(5):1339-1351

The Land Institute, 2440 E. Water Well Road, Salina, KS, 67401,

The American cranberry () is an endemic domesticated species that has become an economically important commercial fruit crop. The USDA-ARS National Clonal Germplasm Repository (NCGR) houses the national collection, which includes representatives of historical cranberry cultivars and wild-selected germplasm. The objective of this study wasto examine the genotypes of 271 cranberry plants from 77 accessions representing 66 named cultivars using 12 simple-sequence repeats to assess clonal purity and cultivar relatedness. Read More

View Article
December 2018

Hybrid corn and the unsettled question of heterosis.

J Genet 2018 Dec;97(5):1075-1082

Directeur de Recherche (retired), INRA, 2 place Pierre Viala, 34000 Montpellier, France.

George Shull's 1908 seminal article 'The composition of a field of maize' marked the 'exploitation of heterosis in plant breeding, surely one of genetics' greatest triumphs'. Hybrid corn became a 'symbol of American agriculture' and 'the paradigm for all developments of F hybrid crop varieties and more generally breeding. But there is still no consensus on the definition of heterosis while its biological basis, causal factors and genetic mechanisms remain 'unknown', or at best 'poorly understood'. Read More

View Article
December 2018

Surgical treatment of lateral and posterior process fractures of the talus: Mid-term results of 15 cases after 7 years.

Foot Ankle Surg 2018 Nov 29. Epub 2018 Nov 29.

Department of Trauma Surgery, Otto-von-Guericke University, Leipziger Str. 44 Magdeburg, Germany.

Background: We retrospectively evaluated the mid-term results of surgery for talar process fractures (lateral and posterior processes) and exploratively analyzed parameters that potentially impact treatment outcomes.

Methods: Fifteen patients who underwent internal fixation (January 2000 to December 2015) were examined for radiological and clinical functional outcomes. The independent parameters evaluated were age, sex, extent of general injury, soft-tissue damage, surgical latency, and fracture type. Read More

View Article
November 2018

Concussion Incidence, Duration, and Return to School and Sport in 5- to 14-Year-Old American Football Athletes.

J Pediatr 2018 Dec 12. Epub 2018 Dec 12.

Center for Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle, WA; Department of Pediatrics, University of Washington, Seattle, WA; Harborview Injury Prevention and Research Center, Seattle, WA.

Objective: To collect prospective data on concussion incidence, risk factors, duration of symptoms, and return to school and sport in 5- to 14-year-old American football participants.

Study Design: We conducted a prospective cohort study over 2 years collecting data during two 10-week fall seasons. Youth with concussion were followed to determine time to return to school, sport, and baseline level of symptoms. Read More

View Article
December 2018

Compression therapy after invasive treatment of superficial veins of the lower extremities: Clinical practice guidelines of the American Venous Forum, Society for Vascular Surgery, American College of Phlebology, Society for Vascular Medicine, and International Union of Phlebology.

J Vasc Surg Venous Lymphat Disord 2019 Jan;7(1):17-28

University of Michigan, Ann Arbor, Mich.

Guideline 1.1: Compression after thermal ablation or stripping of the saphenous veins. When possible, we suggest compression (elastic stockings or wraps) should be used after surgical or thermal procedures to eliminate varicose veins. Read More

View Article
January 2019

A Pediatric Asthma Risk Score to better predict asthma development in young children.

J Allergy Clin Immunol 2018 Dec 7. Epub 2018 Dec 7.

Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio. Electronic address:

Background: Asthma phenotypes are currently not amenable to primary prevention or early intervention because their natural history cannot be reliably predicted. Clinicians remain reliant on poorly predictive asthma outcome tools because of a lack of better alternatives.

Objective: We sought to develop a quantitative personalized tool to predict asthma development in young children. Read More

View Article
December 2018
1 Read

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.

Authors:
Nasim Mavaddat Kyriaki Michailidou Joe Dennis Michael Lush Laura Fachal Andrew Lee Jonathan P Tyrer Ting-Huei Chen Qin Wang Manjeet K Bolla Xin Yang Muriel A Adank Thomas Ahearn Kristiina Aittomäki Jamie Allen Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Kristan J Aronson Paul L Auer Päivi Auvinen Myrto Barrdahl Laura E Beane Freeman Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Leslie Bernstein Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Hiltrud Brauch Michael Bremer Hermann Brenner Adam Brentnall Ian W Brock Angela Brooks-Wilson Sara Y Brucker Thomas Brüning Barbara Burwinkel Daniele Campa Brian D Carter Jose E Castelao Stephen J Chanock Rowan Chlebowski Hans Christiansen Christine L Clarke J Margriet Collée Emilie Cordina-Duverger Sten Cornelissen Fergus J Couch Angela Cox Simon S Cross Kamila Czene Mary B Daly Peter Devilee Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Lorraine Durcan Miriam Dwek Diana M Eccles Arif B Ekici A Heather Eliassen Carolina Ellberg Christoph Engel Mikael Eriksson D Gareth Evans Peter A Fasching Jonine Figueroa Olivia Fletcher Henrik Flyger Asta Försti Lin Fritschi Marike Gabrielson Manuela Gago-Dominguez Susan M Gapstur José A García-Sáenz Mia M Gaudet Vassilios Georgoulias Graham G Giles Irina R Gilyazova Gord Glendon Mark S Goldberg David E Goldgar Anna González-Neira Grethe I Grenaker Alnæs Mervi Grip Jacek Gronwald Anne Grundy Pascal Guénel Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Ute Hamann Susan E Hankinson Elaine F Harkness Steven N Hart Wei He Alexander Hein Jane Heyworth Peter Hillemanns Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Anthony Howell Guanmengqian Huang Keith Humphreys David J Hunter Milena Jakimovska Anna Jakubowska Wolfgang Janni Esther M John Nichola Johnson Michael E Jones Arja Jukkola-Vuorinen Audrey Jung Rudolf Kaaks Katarzyna Kaczmarek Vesa Kataja Renske Keeman Michael J Kerin Elza Khusnutdinova Johanna I Kiiski Julia A Knight Yon-Dschun Ko Veli-Matti Kosma Stella Koutros Vessela N Kristensen Ute Krüger Tabea Kühl Diether Lambrechts Loic Le Marchand Eunjung Lee Flavio Lejbkowicz Jenna Lilyquist Annika Lindblom Sara Lindström Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jirong Long Jan Lubiński Michael P Lux Robert J MacInnis Tom Maishman Enes Makalic Ivana Maleva Kostovska Arto Mannermaa Siranoush Manoukian Sara Margolin John W M Martens Maria Elena Martinez Dimitrios Mavroudis Catriona McLean Alfons Meindl Usha Menon Pooja Middha Nicola Miller Fernando Moreno Anna Marie Mulligan Claire Mulot Victor M Muñoz-Garzon Susan L Neuhausen Heli Nevanlinna Patrick Neven William G Newman Sune F Nielsen Børge G Nordestgaard Aaron Norman Kenneth Offit Janet E Olson Håkan Olsson Nick Orr V Shane Pankratz Tjoung-Won Park-Simon Jose I A Perez Clara Pérez-Barrios Paolo Peterlongo Julian Peto Mila Pinchev Dijana Plaseska-Karanfilska Eric C Polley Ross Prentice Nadege Presneau Darya Prokofyeva Kristen Purrington Katri Pylkäs Brigitte Rack Paolo Radice Rohini Rau-Murthy Gad Rennert Hedy S Rennert Valerie Rhenius Mark Robson Atocha Romero Kathryn J Ruddy Matthias Ruebner Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Daniel F Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Fredrick Schumacher Peter Schürmann Lukas Schwentner Christopher Scott Rodney J Scott Caroline Seynaeve Mitul Shah Mark E Sherman Martha J Shrubsole Xiao-Ou Shu Susan Slager Ann Smeets Christof Sohn Penny Soucy Melissa C Southey John J Spinelli Christa Stegmaier Jennifer Stone Anthony J Swerdlow Rulla M Tamimi William J Tapper Jack A Taylor Mary Beth Terry Kathrin Thöne Rob A E M Tollenaar Ian Tomlinson Thérèse Truong Maria Tzardi Hans-Ulrich Ulmer Michael Untch Celine M Vachon Elke M van Veen Joseph Vijai Clarice R Weinberg Camilla Wendt Alice S Whittemore Hans Wildiers Walter Willett Robert Winqvist Alicja Wolk Xiaohong R Yang Drakoulis Yannoukakos Yan Zhang Wei Zheng Argyrios Ziogas Alison M Dunning Deborah J Thompson Georgia Chenevix-Trench Jenny Chang-Claude Marjanka K Schmidt Per Hall Roger L Milne Paul D P Pharoah Antonis C Antoniou Nilanjan Chatterjee Peter Kraft Montserrat García-Closas Jacques Simard Douglas F Easton

Am J Hum Genet 2018 Dec 5. Epub 2018 Dec 5.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.

Stratification of women according to their risk of breast cancer based on polygenic risk scores (PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, optimized for prediction of estrogen receptor (ER)-specific disease, from the largest available genome-wide association dataset and to empirically validate the PRSs in prospective studies. The development dataset comprised 94,075 case subjects and 75,017 control subjects of European ancestry from 69 studies, divided into training and validation sets. Read More

View Article
December 2018
1 Read