4,282 results match your criteria American Journal of Perinatology[Journal]


Oxygen Saturation and Perfusion Index-Based Enhanced Critical Congenital Heart Disease Screening.

Am J Perinatol 2019 Apr 19. Epub 2019 Apr 19.

Department of Pediatrics, University of California, Davis, Sacramento, California.

Objective:  To determine if addition of perfusion index (PIx) to oxygen saturation (SpO) screening improves detection of critical congenital heart disease (CCHD) with systemic outflow obstruction.

Study Design:  We determined screening thresholds for PIx and applied these to a cohort of newborns with and without congenital heart disease (CHD).

Results:  A total of 123 normal and 21 CHD newborns (including five with critical systemic outflow obstruction) were enrolled. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1685445
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http://dx.doi.org/10.1055/s-0039-1685445DOI Listing
April 2019
1 Read

The Lowering of Bilirubin Levels in Full-Term Newborns by the Effect of Combined Massage Therapy and Phototherapy Practice.

Am J Perinatol 2019 Apr 18. Epub 2019 Apr 18.

Faculty of Medicine, Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.

Objective:  Various therapeutic treatments have been prescribed for decreasing the bilirubin level. Massage therapy is one of the neonate treatments for jaundice. The aim of this study is to investigate the effects of combined massage therapy and phototherapy on neonatal jaundice. Read More

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http://dx.doi.org/10.1055/s-0039-1685493DOI Listing
April 2019
6 Reads

The Accuracy and Cost-Effectiveness of Selective Fetal Echocardiography for the Diagnosis of Congenital Heart Disease in Patients with Pregestational Diabetes Stratified by Hemoglobin A1c.

Am J Perinatol 2019 Apr 16. Epub 2019 Apr 16.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, Ohio.

Objective:  To evaluate the accuracy of antenatal diagnosis of congenital heart disease (CHD) using screening methods including a combination of elevated hemoglobin A1c, detailed anatomy ultrasound, and fetal echocardiography.

Study Design:  This is a retrospective cohort study of all pregnancies complicated by pregestational diabetes from January 2012 to December 2016. The sensitivity, specificity, positive predictive value, and negative predictive value were calculated for each screening regimen. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1685490
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http://dx.doi.org/10.1055/s-0039-1685490DOI Listing
April 2019
1 Read

Sex-Specific Differences in Late Preterm Neonatal Outcomes.

Am J Perinatol 2019 Apr 16. Epub 2019 Apr 16.

Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

Objective:  To estimate sex-specific differences in late preterm outcomes and evaluate whether betamethasone modifies this association.

Study Design:  We conducted a secondary analysis of a multicenter trial of women at risk for late preterm birth randomized to receive betamethasone or placebo. We included women who delivered at 34 to 37 weeks and excluded major fetal anomalies. Read More

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http://dx.doi.org/10.1055/s-0039-1683886DOI Listing
April 2019
1 Read

Effect of Trial of Labor before Cesarean and Risk of Subsequent Placenta Accreta Spectrum Disorders.

Am J Perinatol 2019 Apr 16. Epub 2019 Apr 16.

Department of Obstetrics and Gynecology, Vanderbilt University, Nashville, Tennessee.

Objective:  To examine whether labor before cesarean affects the risk of placenta accreta spectrum (PAS) disorders in a subsequent pregnancy.

Study Design:  This is a secondary analysis of the Cesarean Registry, a prospective cohort study of women undergoing cesarean between 1999 and 2002. Women with one prior cesarean with known indications, which were categorized as likely associated with labor (labored cesarean) versus likely not associated with labor (unlabored cesarean), were included. Read More

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http://dx.doi.org/10.1055/s-0039-1685449DOI Listing
April 2019
2 Reads

Effects of MTNR1B Genetic Variants on Individual Susceptibility to Gestational Diabetes Mellitus: A Meta-Analysis.

Am J Perinatol 2019 Apr 16. Epub 2019 Apr 16.

Department of Nursing, Yulin Traditional Chinese Medicine Hospital, Yulin, Shanxi, China.

Objective:  Whether melatonin receptor 1B () variants are implicated in gestational diabetes mellitus (GDM) remains unclear. Therefore, we performed this meta-analysis to obtain a more conclusive result on associations between variants and GDM.

Study Design:  Literature research was performed in PubMed, Web of Science, Embase, and China National Knowledge Infrastructure. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1685446
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http://dx.doi.org/10.1055/s-0039-1685446DOI Listing
April 2019
4 Reads

SENTINEL1: Two-Season Study of Respiratory Syncytial Virus Hospitalizations among U.S. Infants Born at 29 to 35 Weeks' Gestational Age Not Receiving Immunoprophylaxis.

Am J Perinatol 2019 Apr 16. Epub 2019 Apr 16.

AstraZeneca, Gaithersburg, Maryland.

Objective:  The SENTINEL1 observational study characterized confirmed respiratory syncytial virus hospitalizations (RSVH) among U.S. preterm infants born at 29 to 35 weeks' gestational age (wGA) not receiving respiratory syncytial virus (RSV) immunoprophylaxis (IP) during the 2014 to 2015 and 2015 to 2016 RSV seasons. Read More

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http://dx.doi.org/10.1055/s-0039-1681014DOI Listing
April 2019
6 Reads

How Can Pelvic MRI with Diffusion-Weighted Imaging Help My Pregnant Patient?

Am J Perinatol 2019 Apr 12. Epub 2019 Apr 12.

Division of Abdominal Imaging, Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

The purpose of this review is to explain how diffusion-weighted imaging (DWI) is used during magnetic resonance imaging (MRI) exams in pregnant patients for specific maternal indications, including evaluation of acute pelvic pain, adnexal masses, cancer diagnosis and staging, and morbidly adherent placenta. While ultrasound is often the appropriate initial imaging for evaluating a pregnant patient, MRI can be helpful when a pelvic ultrasound is indeterminate. MRI has advantages in that it does not use ionizing radiation and has shown no known deleterious effects to the fetus. Read More

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http://dx.doi.org/10.1055/s-0039-1685492DOI Listing
April 2019
1 Read

Platelet Counts in Uncomplicated Pregnancies at Term.

Am J Perinatol 2019 Apr 12. Epub 2019 Apr 12.

Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.

Objective:  To evaluate platelet counts at delivery in uncomplicated pregnancies between 37 and 41 weeks of gestation.

Study Design:  Platelet counts in women 16 to 45 years of age from August 1, 2011, through May 15, 2018, with a singleton pregnancy that delivered from 37 to 41 weeks of gestation. Women with pregnancy-related complications, preexisting disorders, or on medications that could affect platelet counts were excluded. Read More

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http://dx.doi.org/10.1055/s-0039-1685447DOI Listing
April 2019
1 Read

Change in Cervical Length across Pregnancies and Preterm Delivery.

Am J Perinatol 2019 Apr 12. Epub 2019 Apr 12.

Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Objective:  To determine whether a decrease in midtrimester cervical length across pregnancies is associated with preterm delivery in a subsequent pregnancy.

Study Design:  This is a cohort study of women who had two consecutive singleton births at the same institution. Midtrimester cervical length change across pregnancies was measured as the difference in centimeters (cm) between cervical lengths using the measurement taken closest to 20 weeks' gestation in each pregnancy. Read More

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http://dx.doi.org/10.1055/s-0039-1685444DOI Listing

Repeated Measures of Cervicovaginal Cytokines during Healthy Pregnancy: Understanding "Normal" Inflammation to Inform Future Screening.

Am J Perinatol 2019 Apr 12. Epub 2019 Apr 12.

Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan.

Objective:  To describe characteristics of cervicovaginal cytokines obtained during pregnancy from women who subsequently delivered at term.

Study Design:  We used repeated measures of 20 cervicovaginal cytokines, collected on average on a monthly basis, from the second to the ninth month of gestation among 181 term pregnancies in the Mexico City Pregnancy Research on Inflammation, Nutrition, & City Environment: Systematic Analyses cohort (2009-2014). Cytokines were quantified using multiplex assay. Read More

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http://dx.doi.org/10.1055/s-0039-1685491DOI Listing

Severe Anemia Is Associated with Intestinal Injury in Preterm Neonates.

Am J Perinatol 2019 Apr 4. Epub 2019 Apr 4.

Department of Neonatalogy, Yildirim Beyazit Universty Faculty of Medicine, Ankara, Turkey.

Background:  A temporal relationship has been reported between necrotizing enterocolitis, anemia, and red blood cell transfusion (RBCT) in preterm neonates. However, the mechanism underlying this association is not clearly defined. Intestinal (I-) and liver (L-) fatty acid binding proteins (FABPs) have been proposed as plasma markers for the detection of acute intestinal injury. Read More

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http://dx.doi.org/10.1055/s-0039-1683982DOI Listing
April 2019
4 Reads

Parental Perceptions and Behaviors Regarding Child Weight Status among Toddlers Born Preterm.

Am J Perinatol 2019 Mar 27. Epub 2019 Mar 27.

Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, Ohio.

Background:  Childhood obesity is a significant determinant of adult obesity. Among children born preterm, rapid "catch-up growth" in infancy increases the risk of later obesity. Parental perceptions of their child's weight status may compound the child's biologically heightened risk of obesity. Read More

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http://dx.doi.org/10.1055/s-0039-1683959DOI Listing
March 2019
1 Read

Neonatal Functional and Structural Connectivity Are Associated with Cerebral Palsy at Two Years of Age.

Am J Perinatol 2019 Mar 27. Epub 2019 Mar 27.

Medpace Imaging Core Laboratory, Medpace Inc., Cincinnati, Ohio.

Objective:  The accuracy of structural magnetic resonance imaging (MRI) to predict later cerebral palsy (CP) in newborns with perinatal brain injury is variable. Diffusion tensor imaging (DTI) and task-based functional MRI (fMRI) show promise as predictive tools. We hypothesized that infants who later developed CP would have reduced structural and functional connectivity as compared with those without CP. Read More

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http://dx.doi.org/10.1055/s-0039-1683874DOI Listing
March 2019
1 Read

Can We Prevent Stillbirth?

Am J Perinatol 2019 Mar 27. Epub 2019 Mar 27.

Department of Obstetrics and Gynecology, Sourasky Medical Center, Lis Maternity Hospital, Tel Aviv University, Tel Aviv, Israel.

Objective:  To identify the frequency of potentially preventable causes of stillbirth in a large heterogeneous population.

Study Design:  This is a retrospective study of all stillbirth cases between January 2011 and December 2016 at a single tertiary medical center. Deliveries resulting from a nonviable fetus prior to 24 weeks of gestation, intrapartum fetal death, and incomplete stillbirth workup were excluded. Read More

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http://dx.doi.org/10.1055/s-0039-1683960DOI Listing
March 2019
2 Reads

Delayed Cord Clamping and Umbilical Cord Milking among Infants in California Neonatal Intensive Care Units.

Am J Perinatol 2019 Mar 21. Epub 2019 Mar 21.

California Perinatal Quality Care Collaborative, Stanford, California.

Objective:  To assess the current practice of delayed cord clamping (DCC) and to determine patient and hospital factors that predict DCC.

Study Design:  The California Perinatal Quality Care Collaborative (CPQCC) collects data on preterm and acutely ill infants. In 2016, 52 CPQCC neonatal intensive care units (NICUs) collected data on DCC. Read More

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http://dx.doi.org/10.1055/s-0039-1683876DOI Listing

The Utility of Soluble CD14 Subtype in Early Diagnosis of Culture-Proven Early-Onset Neonatal Sepsis and Prediction of Outcome.

Am J Perinatol 2019 Mar 21. Epub 2019 Mar 21.

Egyptian Ministry of Health, Cairo, Egypt.

Objective:  To evaluate soluble cluster of differentiation 14 subtype (sCD14-ST), also named presepsin, as an early marker for the diagnosis of culture-proven early-onset sepsis (EOS) in neonates and to assess its relation to disease severity and mortality.

Study Design:  Out of 60 neonates with risk factors of EOS, 31 neonates were diagnosed as having culture-proven EOS. They were compared with 20 nonseptic controls. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1683863
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http://dx.doi.org/10.1055/s-0039-1683863DOI Listing
March 2019
6 Reads

Antibiotics during Intrauterine Balloon Tamponade Is Associated with a Reduction in Endometritis.

Am J Perinatol 2019 Mar 20. Epub 2019 Mar 20.

Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California.

Objective:  To evaluate whether prophylactic antibiotics at the time of placement of an intrauterine balloon tamponade (IBT) is associated with a reduction in postpartum endometritis.

Study Design:  Retrospective cohort study of patients who received an IBT from January 1, 2012, to December 12, 2016. Patients were included if the IBT remained in place at least 2 hours and excluded if chorioamnionitis was present. Read More

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http://dx.doi.org/10.1055/s-0039-1683888DOI Listing
March 2019
1 Read

Correlation between Invasive and Noninvasive Blood Pressure Measurements in Extremely Low Gestational Age Newborns.

Am J Perinatol 2019 Mar 20. Epub 2019 Mar 20.

Department of Pediatrics, Metro Health Medical Center, Case Western Reserve University, Cleveland, Ohio.

Objective:  To study the correlation between invasive blood pressure (IBP) and non-IBP (NIBP) in extremely low gestational age newborns (ELGANs) during their first 72 hours of life.

Study Design:  In a retrospective cohort study, IBP and simultaneous NIBP measurements during the first 72 hours of life were recorded in ELGANs. Medical records were reviewed for potential risk factors that affect BP. Read More

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http://dx.doi.org/10.1055/s-0039-1683981DOI Listing

Cytomegalovirus Infection among Infants in Neonatal Intensive Care Units, California, 2005 to 2016.

Am J Perinatol 2019 Mar 20. Epub 2019 Mar 20.

Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.

Aim:  The main purpose of this article is to assess trends in cytomegalovirus (CMV) infection reported among infants in California neonatal intensive care units (NICUs) during 2005 to 2016.

Study Design:  The California Perinatal Quality Care Collaborative collects data on all very low birth weight (VLBW, birth weight ≤ 1,500 g) and acutely ill infants > 1,500 g, representing 92% of NICUs in California. We compared clinical characteristics and length of hospital stay among infants with and without reported CMV infection (CMV-positive viral culture or polymerase chain reaction). Read More

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http://dx.doi.org/10.1055/s-0039-1683958DOI Listing
March 2019
2 Reads

Utilizing Video versus Direct Laryngoscopy to Intubate Simulated Newborns while Contained within the Incubator: A Randomized Crossover Study.

Am J Perinatol 2019 Mar 20. Epub 2019 Mar 20.

Division of Neonatology, Center of Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.

Objective:  The use of video laryngoscopy for intubating neonates in ergonomically challenging settings has not been studied well. We aimed to assess the usefulness of video laryngoscopy for experienced neonatologists to intubate neonatal manikins in incubators via side hand ports or head window.

Study Design:  In this randomized crossover trial at three neonatal intensive care units in Japan, 27 neonatologists were randomized into two groups, namely, those intubating neonatal simulators using video laryngoscopy and then using direct laryngoscopy, or vice versa. Read More

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http://dx.doi.org/10.1055/s-0039-1683957DOI Listing

Perinatal Outcomes Associated with Early Diabetes Testing in Pregnancies Complicated by Obesity.

Am J Perinatol 2019 Mar 20. Epub 2019 Mar 20.

Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana.

Aim:  To determine whether early diabetes testing is associated with differences in perinatal outcomes among pregnant women with obesity (body mass index ≥30 kg/m).

Study Design:  We conducted a retrospective cohort study of singleton pregnancies from 2012 to 2014 at a large academic medical center which examined the association of diabetes testing (HBA1c, 50 g glucose challenge test, or 100 g oral glucose tolerance test) before 24 weeks with perinatal outcomes using propensity score modeling and logistic regression.

Results:  Among women with obesity, 790 out of 2,698 (29. Read More

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http://dx.doi.org/10.1055/s-0039-1683897DOI Listing
March 2019
1 Read

Duration of Operative Vaginal Delivery and Adverse Obstetric Outcomes.

Am J Perinatol 2019 Mar 20. Epub 2019 Mar 20.

Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, Oregon.

Objective:  To evaluate whether the number of vacuum pop-offs, the number of forceps pulls, or the duration of operative vaginal delivery (OVD) is associated with adverse maternal and perinatal outcomes.

Study Design:  This is a secondary analysis of a multicenter observational cohort of women who underwent an attempted OVD. Women were stratified by the duration of OVD and the number of pop-offs (vacuum) or pulls (forceps) attempted. Read More

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http://dx.doi.org/10.1055/s-0039-1683439DOI Listing
March 2019
1 Read

Pediatric Residency Graduates Preparedness for Neonatal-Perinatal Medicine Fellowship: The Perspective of First-Year Fellows.

Am J Perinatol 2019 Mar 20. Epub 2019 Mar 20.

Department of Pediatrics, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio.

Objective:  To report on Neonatal-Perinatal Medicine (NPM) fellows' views of self-preparedness upon starting postresidency training.

Study Design:  We conducted a national survey of first-year NPM fellows in the United States. The validated survey had five major areas: professionalism, psychomotor ability, independence/graduated responsibility, clinical evaluation, and academia. Read More

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http://dx.doi.org/10.1055/s-0039-1683887DOI Listing

Prevalence and Risk Factors for New-Onset Hypertension in Labor.

Am J Perinatol 2019 Mar 20. Epub 2019 Mar 20.

Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.

Objective:  Little is known about prevalence, risk factors, rate of treatment, or adverse outcomes associated with intrapartum hypertension. Thus, our objective was to describe these findings.

Study Design:  This was a retrospective study of laboring term gestations with no history of hypertensive disorders. Read More

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http://dx.doi.org/10.1055/s-0039-1683875DOI Listing
March 2019
2 Reads

Incidence and Risk Factors for Hospital Readmission or Unexpected Visits in Women Undergoing Unscheduled Cesarean Delivery.

Am J Perinatol 2019 Mar 15. Epub 2019 Mar 15.

Department of Obstetrics and Gynecology, The University of Alabama at Birmingham, Birmingham, Alabama.

Objective:  Hospital readmissions are increasingly tracked and assessed for value-based compensation. Our objective was to determine the incidence and risk factors associated with post-cesarean delivery (CD) readmissions or unexpected visits, defined as unexpected office or emergency room visits.

Study Design:  This is a secondary analysis of a multicenter randomized controlled trial of adjunctive azithromycin prophylaxis for CD performed in laboring patients with viable pregnancies. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1683391
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http://dx.doi.org/10.1055/s-0039-1683391DOI Listing
March 2019
7 Reads

The Effect of Antenatal Vaginal Progesterone Administration on Uterine, Umbilical, and Fetal Middle Cerebral Artery Doppler Flow: A Cohort Study.

Am J Perinatol 2019 Mar 13. Epub 2019 Mar 13.

Department of Gynecology and Obstetrics, Faculty of Medicine, Fayoum University, Fayoum, Egypt.

Objective:  To evaluate the effect of vaginal progesterone (P) administration during the second and third trimesters of pregnancy on Doppler velocimetry of uterine, umbilical, and middle cerebral vessels.

Study Design:  A prospective cohort study conducted on 80 women at risk for preterm labor. Uterine artery, umbilical artery, and middle cerebral artery (MCA) Doppler indices were measured before and after 1 week of administration of 200 mg twice daily vaginal P. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1683438
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http://dx.doi.org/10.1055/s-0039-1683438DOI Listing
March 2019
10 Reads

Effect of Treatment of Mild Gestational Diabetes on Long-Term Maternal Outcomes.

Am J Perinatol 2019 Mar 13. Epub 2019 Mar 13.

Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, South Carolina.

Objective:  The main purpose of this article is to evaluate whether identification and treatment of women with mild gestational diabetes mellitus (GDM) during pregnancy affects subsequent maternal body mass index (BMI), anthropometry, metabolic syndrome, and risk of diabetes.

Study Design:  This is a follow-up study of women who participated in a randomized controlled treatment trial for mild GDM. Women were enrolled between 5 and 10 years after their index pregnancy. Read More

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http://dx.doi.org/10.1055/s-0039-1681058DOI Listing
March 2019
12 Reads

A Validation Study of Maternal Early Warning Systems: A Retrospective Cohort Study.

Am J Perinatol 2019 Mar 11. Epub 2019 Mar 11.

Department of Obstetrics and Gynecology, Long Beach Memorial Miller Children's and Women's Hospital, Long Beach, California.

Objective:  We compare validation characteristics of four early warning systems for maternal morbidity.

Study Design:  We used a retrospective cohort of severe maternal morbidity cases between January 2016 and December 2016 compared with a cohort of controls. We determined if the modified early obstetric warning score (MEOWS), maternal early recognition criteria (MERC), modified early warning system (MEWS), or maternal early warning trigger (MEWT) would have alerted. Read More

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http://dx.doi.org/10.1055/s-0039-1681097DOI Listing
March 2019
1 Read

Neonatal Outcomes Associated with Umbilical Cord Milking in Preterm Multiple Gestations.

Am J Perinatol 2019 Mar 1. Epub 2019 Mar 1.

Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, Utah.

Objective:  Our aim was to evaluate the effect of umbilical cord milking on outcomes for preterm multiples.

Study Design:  We implemented a policy of cord milking in neonates born at less than 30 weeks' gestation in September 2011. We compared cord milking in multiples with a historical cohort. Read More

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http://dx.doi.org/10.1055/s-0039-1679915DOI Listing
March 2019
1 Read

Disparate Rates of Cesarean Delivery in Term Nulliparous Women with Hypertensive Disorders of Pregnancy.

Am J Perinatol 2019 Mar 1. Epub 2019 Mar 1.

Department of Obstetrics and Gynecology, University of California, Irvine Medical Center, Orange, California.

Objective:  To evaluate the prevalence of cesarean delivery in women with hypertensive disorders of pregnancy (HDP), and explore whether maternal, sociodemographic, or obstetric comorbidities contribute to cesarean delivery rates.

Study Design:  This is a retrospective cohort study of nulliparous, term, singleton, vertex women using the 2013 U.S. Read More

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http://dx.doi.org/10.1055/s-0039-1681057DOI Listing
March 2019
2 Reads

Multimodal Pain Management for Cesarean Delivery: A Double-Blinded, Placebo-Controlled, Randomized Clinical Trial.

Am J Perinatol 2019 Mar 1. Epub 2019 Mar 1.

Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, Texas.

Objective:  Our objective was to evaluate the efficacy of perioperative multimodal pain management in reducing opioid use after elective cesarean delivery (CD).

Study Design:  A single-center, double-blinded, placebo-controlled randomized trial of women undergoing elective CD. Participants were allocated 1:1 to receive the multimodal protocol or matching placebos. Read More

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http://dx.doi.org/10.1055/s-0039-1681096DOI Listing
March 2019
4 Reads

Delayed Achievement of Oral Feedings Is Associated with Adverse Neurodevelopmental Outcomes at 18 to 26 Months Follow-up in Preterm Infants.

Am J Perinatol 2019 Mar 1. Epub 2019 Mar 1.

Division of Neonatology, Department of Pediatrics, Connecticut Children's Medical Center, University of Connecticut School of Medicine, Hartford, Connecticut.

Objective:  To compare neurodevelopmental outcomes in preterm infants at 18 to 26 months corrected age (CA) who did versus did not achieve full oral feedings at 40 weeks postmenstrual age (PMA).

Study Design:  This retrospective study included infants born between 2010 and 2015 with gestational age <32 weeks and followed between 18 and 26 months CA. Achievement of full oral feedings was defined as oral intake >130 mL/kg/d for >72 hours by 40 weeks PMA. Read More

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http://dx.doi.org/10.1055/s-0039-1681059DOI Listing
March 2019
1 Read

Resuscitation Quality Metrics for the Newly Born.

Am J Perinatol 2019 Mar 1. Epub 2019 Mar 1.

Division of Neonatology, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1055/s-0039-1681098DOI Listing
March 2019
1 Read

Real-Time Continuous Glucose Monitoring in Gestational Diabetes: A Randomized Controlled Trial.

Am J Perinatol 2019 Feb 28. Epub 2019 Feb 28.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia.

Objective:  To evaluate whether real-time continuous glucose monitoring improves glycemic control over intermittent self-monitoring of blood glucose in gestational diabetes.

Study Design:  We performed a single-institution randomized controlled trial. Patients with gestational diabetes were randomized to use either real-time or blinded continuous glucose monitoring. Read More

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http://dx.doi.org/10.1055/s-0039-1678733DOI Listing
February 2019
1 Read

Estimating Gestational Age from Ultrasound: External Validation of the NICHD Formula with Comparison to the Hadlock Regression.

Am J Perinatol 2019 Feb 28. Epub 2019 Feb 28.

Department of Obstetrics and Gynecology, Center for Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, Alabama.

Objective:  To externally validate the National Institute of Child Health and Human Development (NICHD) formula developed from the National Fetal Growth Studies-Singletons and compare with 1984 Hadlock regression in a general obstetrical population.

Study Design:  Cross-sectional study of nonanomalous singletons with a crown-rump length (CRL) and ≥1 additional ultrasound (US) with complete fetal biometrics. CRL established the referent estimated due date to calculate the error at every examination from both formulas. Read More

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http://dx.doi.org/10.1055/s-0039-1681055DOI Listing
February 2019
1 Read

Comparison of Continuation of Low-Molecular-Weight Heparin versus Switching to Unfractionated Heparin in the Peripartum.

Am J Perinatol 2019 Feb 28. Epub 2019 Feb 28.

Division of Maternal Fetal Medicine, University of Illinois at Chicago, Chicago, Illinois.

Objective:  This study aimed to determine whether switching from low-molecular-weight heparin (LMWH) to unfractionated heparin (UFH) or its continuation in the peripartum affected anesthesia choice or bleeding complications.

Study Design:  A retrospective cohort study of 189 anticoagulated pregnant women who delivered at the University of Illinois at Chicago Hospital and Health Science System from 2005 to 2016. Demography, anesthesia choice, and bleeding complications were compared between the two groups. Read More

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http://dx.doi.org/10.1055/s-0039-1678667DOI Listing
February 2019
1 Read

Electronic Fetal Monitoring and Neonatal Outcomes when a Nuchal Cord Is Present at Delivery.

Am J Perinatol 2019 Feb 28. Epub 2019 Feb 28.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri.

Objective:  To determine the association between nuchal cord, electronic fetal monitoring parameters, and adverse neonatal outcomes.

Study Design:  This was a prospective cohort study of 8,580 singleton pregnancies. Electronic fetal monitoring was interpreted, and patients with a nuchal cord at delivery were compared with those without. Read More

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http://dx.doi.org/10.1055/s-0039-1679866DOI Listing
February 2019
2 Reads

Achieving Baby-Friendly Designation at a Large Metropolitan Center.

Am J Perinatol 2019 Feb 28. Epub 2019 Feb 28.

Department of Obstetrics and Gynecology, Montefiore Medical Center, Jack D. Weiler Hospital, Bronx, New York.

Objective:  To describe the journey of obtaining Baby-Friendly designation as a large metropolitan center in an urban city and review the initial patient-related outcomes.

Study Design:  Our medical center participated in the New York City Department of Health and Mental Hygiene Breastfeeding Hospital Collaborative from 2012 to 2017. Monthly meetings were held to monitor data, and audits conducted among prenatal sites and maternity units. Read More

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http://dx.doi.org/10.1055/s-0039-1681056DOI Listing
February 2019
6 Reads

Developing a Core Outcome Set for Cesarean Delivery Maternal Infectious Morbidity Outcomes.

Am J Perinatol 2019 Feb 28. Epub 2019 Feb 28.

Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana.

Objective:  To develop a core outcome set of primary outcomes for studies involving cesarean deliveries with infectious morbidity outcomes.

Study Design:  Authors reported primary outcomes from 11 Cochrane systematic reviews (SRs), 12 other SRs, and 327 randomized controlled trials (RCTs). These outcomes were condensed into 20 primary outcome groups. Read More

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http://dx.doi.org/10.1055/s-0039-1681095DOI Listing
February 2019
2 Reads

Accuracy of Routine Prenatal Genetic Screening in Patients Referred for Genetic Counseling.

Am J Perinatol 2019 Feb 22. Epub 2019 Feb 22.

Department of Obstetrics and Gynecology, Christiana Care Health System, Newark, Delaware.

Objective:  The American College of Obstetricians and Gynecologists (ACOG) guidelines recommend routine prenatal screening for genetic diseases that could affect the pregnancy. We sought to determine the rate of missed genetic information in the general obstetrician's routine prenatal genetic screening process.

Study Design:  This is a sequential case series of women referred for genetic counseling between March and August of 2015. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1678533
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http://dx.doi.org/10.1055/s-0039-1678533DOI Listing
February 2019
4 Reads

Impact of Azithromycin-Based Extended-Spectrum Antibiotic Prophylaxis on Noninfectious Cesarean Wound Complications.

Am J Perinatol 2019 Feb 19. Epub 2019 Feb 19.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama.

Objective:  Adding azithromycin to standard antibiotic prophylaxis for unscheduled cesarean delivery has been shown to reduce postcesarean infections. Because wound infection with ureaplasmas may not be overtly purulent, we assessed the hypothesis that azithromycin-based extended-spectrum antibiotic prophylaxis also reduces wound complications that are identified as noninfectious.

Study Design:  This is a secondary analysis of the C/SOAP (Cesarean Section Optimal Antibiotic Prophylaxis) randomized controlled trial, which enrolled women with singleton pregnancies ≥24 weeks who were undergoing nonelective cesarean. Read More

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http://dx.doi.org/10.1055/s-0039-1679914DOI Listing
February 2019
6 Reads

Maternal and Infant Adverse Outcomes Associated with Mild and Severe Preeclampsia during the First Year after Delivery in the United States.

Am J Perinatol 2019 Feb 19. Epub 2019 Feb 19.

Division of Neonatal and Developmental Medicine, Lucile Packard Children's Hospital, Stanford University School of Medicine, Stanford, California.

Background:  The burden of preeclampsia severity on the health of mothers and infants during the first year after delivery is unclear given the lack of population-based longitudinal studies in the United States.

Methods:  We assessed maternal and infant adverse outcomes during the first year after delivery using population-based hospital discharge information merged with vital statistics and birth certificates of 2,021,013 linked maternal-infant births in California. We calculated sampling weights using the National Center for Health Statistics data to adjust for observed differences in maternal characteristics between California and the rest of the United States. Read More

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http://dx.doi.org/10.1055/s-0039-1679916DOI Listing
February 2019
1 Read

Comparison of Endotracheal Reintubation between Nasal High-Frequency Oscillation and Continuous Positive Airway Pressure in Neonates.

Am J Perinatol 2019 Feb 19. Epub 2019 Feb 19.

Division of Neonatology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.

Objective:  To compare the endotracheal reintubation between nasal high-frequency oscillation (nHFO) and nasal continuous positive airway pressure (nCPAP) with face mask groups who were followed up for up to 7 days.

Study Design:  We performed a retrospective cohort study of extubated neonates admitted between 2013 and 2017. We used a Cox's proportional hazards model to adjust for significant between-group differences in baseline characteristics. Read More

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http://dx.doi.org/10.1055/s-0039-1679932DOI Listing
February 2019
2 Reads

Weight-Based Guide Overestimates Endotracheal Tube Tip Position in Extremely Preterm Infants.

Am J Perinatol 2019 Feb 19. Epub 2019 Feb 19.

Neonatal Unit, Aberdeen Maternity Hospital, Aberdeen, United Kingdom.

Objective:  To evaluate the association between endotracheal tube (ETT) tip position and adverse pulmonary outcomes using chest X-ray (CXR) in extremely preterm infants in whom ETT insertion length was estimated using weight + 6 guide (adding 6 cms to the infant's weight in kg).

Study Design:  CXRs of 85 infants performed in the first week were reviewed for right-sided atelectasis, air leaks, and uneven lung inflation. The first CXR was later reviewed to document the ETT tip. Read More

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http://dx.doi.org/10.1055/s-0039-1678531DOI Listing
February 2019
1 Read

Use of Point-of-Care Gastric pH Testing to Assess the Efficacy of Acid Suppression Therapy in the Neonatal Intensive Care Unit.

Am J Perinatol 2019 Feb 19. Epub 2019 Feb 19.

Division of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.

Objective:  The use of acid suppression therapies in newborns lacks efficacy and is associated with adverse effects. Point-of-care (POC) assessment of gastric aspirate pH may provide an objective, noninvasive measure of gastric acidity in tube fed infants. We conducted the present study to characterize the POC gastric pH levels in gastric tube fed infants before and after initiation of enteral omeprazole or ranitidine. Read More

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http://dx.doi.org/10.1055/s-0039-1679917DOI Listing
February 2019
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Lower Extremity Blood Flow Velocity in Obese versus Nonobese Pregnant Women.

Am J Perinatol 2019 Feb 19. Epub 2019 Feb 19.

Department of Obstetrics and Gynecology, University of Texas Medical Branch at Galveston, Galveston, Texas.

Background:  Obesity and pregnancy are risk factors for venous thromboembolism (VTE). In nonpregnant individuals, abdominal obesity is associated with venous insufficiency.

Objective:  To compare venous Doppler volume flow and velocity in the lower extremities of obese versus nonobese women. Read More

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http://dx.doi.org/10.1055/s-0039-1679867DOI Listing
February 2019

Oral Opioid Use during Vaginal Delivery Hospitalizations.

Am J Perinatol 2019 Feb 12. Epub 2019 Feb 12.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York.

Objective:  To determine the receipt of short-acting opioid medications during vaginal delivery hospitalizations.

Study Design:  The Perspective database was analyzed to evaluate patterns of short-acting oral opioid use during vaginal delivery hospitalizations from January 2006 to March 2015. Unadjusted and adjusted models evaluating the role of demographic and hospital factors were created evaluating use of opioids. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1678566
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http://dx.doi.org/10.1055/s-0039-1678566DOI Listing
February 2019
23 Reads

A Regression Model for Prediction of Cesarean-Associated Blood Transfusion.

Am J Perinatol 2019 Feb 11. Epub 2019 Feb 11.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Women and Infants Hospital, Alpert Medical School of Brown University, Providence, Rhode Island.

Objective:  To develop a model to predict cesarean-associated red blood cell transfusion.

Study Design:  Secondary analysis of all cesarean deliveries in the Maternal-Fetal Medicine Units Network Cesarean Registry. Using a split-sample technique, the derivation group was used to identify associated factors and build predictive models, and the validation group was used to estimate classification errors and determine test characteristics. Read More

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http://dx.doi.org/10.1055/s-0039-1678604DOI Listing
February 2019
5 Reads

Social Determinants of Gestational Weight Gain in an Obese, Low-Income Population.

Am J Perinatol 2019 Feb 11. Epub 2019 Feb 11.

Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.

Objective:  To examine how social support factors affect compliance with gestational weight gain (GWG) recommendations in an obese, low-income, predominantly minority population.

Study Design:  A retrospective cohort of 772 pregnant women with body mass index > 30 was reviewed. Univariate and multinomial logistic regression analyses were used to compare GWG with pregnancy planning, relationship status, participation in group prenatal care, nutritional education, and demographic factors. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1678606
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http://dx.doi.org/10.1055/s-0039-1678606DOI Listing
February 2019
17 Reads