3,648 results match your criteria American Journal of Otolaryngology[Journal]


Recurrent apocrine hidrocystoma of the external auditory canal.

Am J Otolaryngol 2019 Jan 28. Epub 2019 Jan 28.

Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, USA; Department of Biomedical Engineering, University of California, Irvine, USA. Electronic address:

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http://dx.doi.org/10.1016/j.amjoto.2019.01.011DOI Listing
January 2019

Reliability of clinical diagnosis of masses of the cerebellopontine angle: A retrospective multi-institutional study.

Am J Otolaryngol 2019 Jan 28. Epub 2019 Jan 28.

Department of Neurotology, Michigan Ear Institute, St. John Providence Hospital and Medical Centers, 30055 Northwestern Highway, Suite #101, Farmington Hills, MI 48334, United States. Electronic address:

Objectives: To assess the accuracy of pre-operative diagnosis of masses of the cerebellopontine angle (CPA) when compared to surgical pathology.

Design: Retrospective chart review.

Participants: Patients who underwent surgery for CPA masses at two tertiary care institutions from 2007 to 2017. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.01.009DOI Listing
January 2019

The factors associated with the early diagnosis of nasal NK/T-cell lymphoma with prominent ocular symptoms and general nasal NKTL.

Am J Otolaryngol 2019 Jan 28. Epub 2019 Jan 28.

Department of Nose, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China. Electronic address:

Aim: This study explored the clinical features of nasal natural killer/T-cell lymphoma (NKTL) in patients with prominent ocular symptoms and those with general nasal NKTL to improve the early diagnosis of nasal NKTL.

Method: A retrospective cohort study was performed with 278 patients with nasal NKTL admitted to the First Affiliated Hospital of Zhengzhou University between January 2011 and December 2017. Of these cases, 56 presented with nasal NKTL and prominent ocular symptoms, and 222 presented with general nasal NKTL. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.01.012DOI Listing
January 2019
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Management of jugular bulb injury during drilling of the internal auditory canal (ICA) for vestibular schwannoma surgery.

Am J Otolaryngol 2019 Jan 24. Epub 2019 Jan 24.

Department of Neurosurgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

The retrosigmoid approach for vestibular schwannoma surgery has remained the standard approach by most neurosurgeons. Drilling the posterior wall of the internal auditory meatus (IAM) is an essential step in removing the intrameatal tumor. During IAM drilling, three anatomical structures can be encountered, including the posterior semicircular canal, vestibular aqueduct, and jugular bulb. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.01.004DOI Listing
January 2019

Retrograde parotidectomy under local anesthesia for benign, malignant, and inflammatory lesions.

Am J Otolaryngol 2019 Jan 14. Epub 2019 Jan 14.

Department of Otolaryngology-Head and Neck Surgery, Stanford University, 801 Welch Road, Stanford, CA, USA 94305. Electronic address:

Objective: To report the patient selection, surgical technique, and outcomes of parotidectomy using local anesthesia under monitored anesthesia care (MAC).

Methods: A retrospective chart review was performed for patients undergoing parotidectomy under local anesthesia at an academic head and neck surgery center.

Results: Six patients deemed high risk for general anesthesia (GA) due to medical comorbidities or with a strong preference to avoid GA underwent parotidectomy using local anesthesia and MAC. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.01.002DOI Listing
January 2019
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The effects of different packing materials on healing and hearing after trauma to middle ear mucosa, an experimental study in rats.

Am J Otolaryngol 2019 Jan 20. Epub 2019 Jan 20.

Numune Training and Research Hospital, Department of Otolaryngology, Ankara, Turkey.

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http://dx.doi.org/10.1016/j.amjoto.2019.01.006DOI Listing
January 2019

Nuclear expression of onco-suppressors nm23-H1 and maspin are associated with lower recurrence rate in laryngeal carcinoma.

Am J Otolaryngol 2018 Nov 22. Epub 2018 Nov 22.

Department of Medicine DIMED, University of Padova, Padova, Italy.

Purpose: The main aim of the study was to preliminarily investigate the possibly related role of nuclear onco-suppressors maspin and nm23-H1, a metastasis suppressor, in laryngeal squamous cell carcinoma (LSCC).

Materials And Methods: Maspin expression pattern and nuclear nm23-H1 expression were ascertained in 62 consecutive LSCCs.

Results: Recurrence rate was significantly lower in patients with a nuclear maspin pattern of expression; nuclear nm23-H1 expression was significantly lower in patients who experienced disease recurrence. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.11.007DOI Listing
November 2018
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Topical Mitomycin-C can help as an adjunct to alkaline nasal wash and rifampicin in primary atrophic rhinitis.

Am J Otolaryngol 2019 Jan 16. Epub 2019 Jan 16.

Otolaryngology, Head and Neck Department, Minia Medical Insurance Hospital, Minia, Egypt.

Purpose: Primary atrophic rhinitis (PAR) is a well-known old disease characterized by a roomy nose and extensive crustations. This study was designed to investigate the effect of topical Mitomycin-C as an adjunct to medical treatment with respect to objective and subjective improvement in patients treated with PAR.

Material And Methods: This prospective randomized controlled study was conducted in a tertiary referral hospital in January 2016 and March 2018. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.01.007DOI Listing
January 2019

Isolated horizontal canal hypofunction differentiating a canalith jam from an acute peripheral vestibular loss.

Am J Otolaryngol 2018 Dec 7. Epub 2018 Dec 7.

ENT & Audiology Unit, Department of Experimental Diagnostic and Specialty Medicine (DIMES), S. Orsola - Malpighi University Hospital, Via Massarenti 9, 40138 Bologna, Italy.

Objectives: To describe a unique case of acute vertigo presenting with spontaneous horizontal nystagmus (SHN) and a clinical picture consistent with right acute peripheral vestibular loss (APVL) in which an isolated hypofunction of a horizontal semicircular canal (HSC) permitted to detect a spontaneous canalith jam and treat the patient accordingly.

Methods: Case report and literature review.

Results: A 74-year old woman presented with acute vertigo, left-beating SHN and a clinical picture consistent with right APVL. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.12.005DOI Listing
December 2018

Assessing the educational quality of 'YouTube' videos for facelifts.

Am J Otolaryngol 2019 Jan 4. Epub 2019 Jan 4.

Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA. Electronic address:

Objectives: Facelifts are among the most common facial plastic procedures performed. Given the existence of a variety of surgical approaches and the proximity of key anatomical structures, the development of proper surgical skills and knowledge is necessary to ensure positive outcomes. Many surgical learners utilize YouTube videos as supplemental tools in their education. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.01.001DOI Listing
January 2019
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Is there any effect of anxiety and depression scores on the improvement of tinnitus after surgery in chronic otitis patients with tinnitus.

Am J Otolaryngol 2018 Nov 22. Epub 2018 Nov 22.

Haseki Training and Research Hospital, Dept. of Otorhinolaryngology Fatih, Istanbul, Turkey.

Background: Tinnitus is a common disease in public. It is not only associated with neuronal, muscular, vascular pathologies, but also with related psychological parameters. In this study, we aimed to investigate the relationship between tinnitus, anxiety and depression in patients undergoing tympanoplasty. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.11.006DOI Listing
November 2018
2 Reads

Syphilis of the oropharynx: Case series of "The Great Masquerader".

Am J Otolaryngol 2019 Jan 16. Epub 2019 Jan 16.

Department of Otolaryngology - Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.

Objective: Syphilis is a sexually transmitted infection with various presentations. Although, oropharyngeal manifestations are known to occur, the purpose of this study is to present the first case series in which the lesions were initially mistaken for human-papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC).

Methods: A multi-institutional retrospective review. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709183113
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http://dx.doi.org/10.1016/j.amjoto.2019.01.005DOI Listing
January 2019
8 Reads

Identification of key genes and pathways in chronic rhinosinusitis with nasal polyps using bioinformatics analysis.

Am J Otolaryngol 2018 Dec 5. Epub 2018 Dec 5.

Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, Changsha, Hunan, China; Province Key Laboratory of Otolaryngology Critical Diseases, Changsha, Hunan, China. Electronic address:

Purpose: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a prevalent inflammatory disease of yet unknown etiology. The purpose of this study was to uncover key genes and pathways related to the pathogenesis of CRSwNP via bioinformatics approaches.

Materials And Methods: The gene expression profile of GSE36830 extracted from Gene Expression Omnibus database was used to screen differentially expressed genes (DEGs) between nasal polyp samples and control samples. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709183101
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http://dx.doi.org/10.1016/j.amjoto.2018.12.002DOI Listing
December 2018
5 Reads

Anesthetic management for medialization laryngoplasty using concurrent infusions of dexmedetomidine, remifentanil, and propofol versus controls.

Am J Otolaryngol 2019 Jan 11. Epub 2019 Jan 11.

Mayo Clinic, Department of Anesthesiology and Perioperative Medicine, Rochester, MN, USA. Electronic address:

Purpose: Medialization laryngoplasty (ML) ± arytenoid adduction (AA) surgery poses a unique anesthetic challenge that requires periods of deep sedation and patient cooperation with phonation to assess voice function. The purpose of this study was to assess if the protocolized administration of dexmedetomidine, remifentanil, and propofol (DRP) is associated with reduced procedural duration and administration of other sedating medications.

Materials And Methods: This was a retrospective 2:1 case matched study design; matched on age, sex, body mass index, AA, and surgical revision status. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.01.003DOI Listing
January 2019
2 Reads

Evaluating the effect of nasal septoplasty on atrial electromechanical features.

Am J Otolaryngol 2018 Dec 15. Epub 2018 Dec 15.

Otolaryngeaolgy, Duzce University Medical School, 81100 Duzce, Turkey.

Background: Recent studies have demonstrated that right ventricular (RV) dysfunction and increased pulmonary artery pressure may be frequent in patients with upper airway obstruction. In this study, we evaluated atrial conduction delays in patients with upper airway obstruction secondary to nasal septum deviation (NSD).

Methods: A total of 32 patients with upper airway obstruction secondary to NSD undergoing a septoplasty procedure were enrolled in this study. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.12.007DOI Listing
December 2018
2 Reads

Is otitis media with effusion associated with oxidative stress? Evaluation of thiol/disulfide homeostasis.

Am J Otolaryngol 2018 Dec 27. Epub 2018 Dec 27.

Erzurum Regional Training and Research Hospital, Department of Endocrinology, Erzurum, Turkey.

Background: We evaluated the relationship between otitis media with effusion and thiol/disulfide homeostasis using a novel marker of oxidative stress.

Methods: The study group consisted of 30 patients (mean age 8.33 ± 3. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.12.012DOI Listing
December 2018
1 Read
1.078 Impact Factor

Radiotherapy for parapharyngeal space tumors.

Am J Otolaryngol 2018 Dec 21. Epub 2018 Dec 21.

Coordinator of the International Head and Neck Scientific Group, Padua, Italy.

A wide variety of tumors, both benign and malignant, occur in the parapharyngeal space. Depending on histology and extent, treatment may include surgery and/or radiotherapy (RT). Herein we discuss the role of RT in the management of some of the more commonly encountered neoplasms, including salivary gland tumors, paragangliomas, schwannomas, and soft-tissue sarcomas. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.12.010DOI Listing
December 2018
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Investigating the role of octamer binding transcription Factor-4 (Oct-4) in oral cavity squamous cell carcinoma: A systematic review and meta-analysis.

Am J Otolaryngol 2018 Dec 21. Epub 2018 Dec 21.

Department of Otolaryngology, Head and Neck Surgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.amjoto.2018.12.011DOI Listing
December 2018
1 Read

Bacterial cellulose graft versus fat graft in closure of tympanic membrane perforation.

Am J Otolaryngol 2018 Dec 18. Epub 2018 Dec 18.

Faculty of science, Benha University, Egypt.

Object: To compare between results of bacterial cellulose graft myringoplasty and fat graft myingoplasty in patients had mild or moderate size safe perforation.

Methods: 120 patients undergoing myringoplasty due to mild or moderate size perforation were divided into 3 groups: group I: 40 patients undergoing myringoplasty with use of bacterial cellulose graft, group II: 40 patients undergoing myringoplasty with use of fat graft, group III: 40 patients undergoing usual myringoplasty with use of temporalis fascia graft (control group).

Results: Healing in 20 patients with small perforation and 17 patients with moderate perforation in Group I, Healing in 15 patients with small perforation and 10 patients with moderate perforation in Group II, Healing in 18 patients with small perforation and 12 patients with moderate perforation in Group III. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.12.008DOI Listing
December 2018
2 Reads

The relationship between IL-17A and IL-22 expression and clinical severity in patients with moderate/severe persistent allergic rhinitis.

Am J Otolaryngol 2018 Dec 18. Epub 2018 Dec 18.

Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Purpose: Several reactions leading to numerous effects are regulated by IL-22. However, the relationship between IL-22 and immunopathogensis of allergic rhinitis (AR) has been rarely investigated. The aim of the present study was to investigate the levels of IL-22 and IL-17A in AR patients and their association with clinical severity of persistent allergic rhinitis (PAR). Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.12.009DOI Listing
December 2018
2 Reads
1.078 Impact Factor

Free thyroid transfer to anterolateral thigh for prevention of radiation induced hypothyroidism: An initial experience.

Am J Otolaryngol 2018 Dec 21. Epub 2018 Dec 21.

Jaslok Hospital and Research Centre, Pedder Road, Mumbai, India; Bombay Hospital and Research Centre, Marine Lines, Mumbai, India.

Aim: Radiation induced hypothyroidism (RIHT) is one of the commonest late side effects of radiation therapy and is seen in more than half of patients and affects quality of life significantly. We report our initial experience on feasibility of free microvascular transfer of thyroid gland out of radiation field to prevent development of RIHT.

Material And Methods: A prospective pilot study was undertaken during August 2017 to May 2018. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709183110
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http://dx.doi.org/10.1016/j.amjoto.2018.12.013DOI Listing
December 2018
6 Reads

Osteoradionecrosis of the hyoid bone complicated by pharyngocutaneous fistula: A case report and literature review.

Am J Otolaryngol 2018 Dec 7. Epub 2018 Dec 7.

THANC (Thyroid, Head and Neck Cancer) Foundation, 10 Union Square East, Suite 5B, New York, NY 10003, USA; Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, Mount Sinai Beth Israel Medical Center, 10 Union Square East, Suite 5B, New York, NY 10003, USA.

Background: Osteoradionecrosis (ORN) is a well-known complication following irradiation of head and neck malignancies. ORN commonly occurs in the mandible but is rarely reported in the hyoid bone.

Case Presentation: A 76-year-old female with a history of oropharyngeal squamous cell carcinoma presented with pharyngocutaneous fistula 14 years after primary chemoradiation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709183109
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http://dx.doi.org/10.1016/j.amjoto.2018.12.006DOI Listing
December 2018
7 Reads

Polysomnographic and pulmonary function changes in patients with sleep problems after septoplasty with turbinectomy.

Am J Otolaryngol 2018 Dec 11. Epub 2018 Dec 11.

Faculty of Medicine, Department of Chest Diseases, Kafr Elsheikh University, Kafr El-Sheikh Faculty of Medicine, Egypt. Electronic address:

Object: To compare Polysomnography and Pulmonary function tests before and after Septoplasty with Turbinectomy in patients complaining of nasal obstruction and sleep problems due to deviated septum with hypertrophic inferior turbinate.

Methods: 90 patients underwent Septoplasty with Turbinectomy due to nasal obstruction and sleep problems involved in this study, their sleep quality evaluated by polysomnography before and after the surgery, their pulmonary functions assessed by spirometry before and after the operation.

Results: The postoperative pulmonary function values; FVC, FEV1, PEFR and postoperative polysomonographic values; AHI, Snoring index/hour, SpaO2 were higher than the preoperative values, and the results were statistically significant (p-values <0. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.12.003DOI Listing
December 2018
1 Read

Quality of life related to symptomatic outcomes in patients with vestibular schwannomas: A Canadian Centre perspective.

Am J Otolaryngol 2018 Nov 22. Epub 2018 Nov 22.

Division of Neurosurgery, QEII Halifax Infirmary Site, 3rd Floor, 1796 Summer Street, Halifax, NS B3H 3A7, Canada; Maritime Lateral Skull Base Clinic: Divisions of Neurosurgery, OtolaryngologyHead & Neck Surgery, Canada; Department of Radiation Oncology, Dalhousie University, QEII Health Sciences Centre, 3rd floor Dickson Building, 5820 University Avenue, Halifax, NS B3H 1Y9, Canada.

Patients with vestibular schwannomas (VS) typically present with hearing loss and tinnitus as well as variable cranial nerve dysfunctions. Surgical resection, stereotactic radiotherapy and/or conservative management employing serial magnetic resonance or computed tomography imaging serve as the main treatment options. Quality of life (QoL) may be impacted by the extent of tumour burden and exacerbated or relieved by treatment. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709183098
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http://dx.doi.org/10.1016/j.amjoto.2018.11.004DOI Listing
November 2018
9 Reads

Excision of preauricular sinus with abscess drainage in children.

Am J Otolaryngol 2018 Nov 16. Epub 2018 Nov 16.

Department of Otolaryngology, Affiliated Zhongshan Hospital of Dalian University, China. Electronic address:

Purpose: To introduce a feasible approach for excising a preauricular sinus with abscess in children.

Materials And Methods: Patients under 14 years old with a preauricular sinus abscess and volunteering for surgery were involved in this study.

Results: Neither recurrence nor local deformity was found in these patients with a follow-up of 3 to 72 months. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709183094
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http://dx.doi.org/10.1016/j.amjoto.2018.10.016DOI Listing
November 2018
9 Reads

Submental flap for reconstruction of anterior skull base, orbital, and high facial defects.

Am J Otolaryngol 2018 Nov 22. Epub 2018 Nov 22.

Purpose: Large anterior skull base, orbital, and high facial defects can present a challenging reconstructive problem. Limited data exists in the literature on the use of a submental flap for reconstructing such defects. We aimed to describe the feasibility, success, and advantages of using variations of the submental flap for reconstruction of anterior skull base, orbital, and high facial defects. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.11.008DOI Listing
November 2018
1 Read

Comparative study of epidermal growth factor and observation only on human subacute tympanic membrane perforation.

Am J Otolaryngol 2018 Nov 27. Epub 2018 Nov 27.

Department of Clinical Medicine, Xinxiang Medical University, Xinxiang City 453003, Henan Province, China.

Objective: To compare the effects of epidermal growth factor (EGF) and observation only on human subacute tympanic membrane perforation (TMP).

Methods: A total of 44 patients with traumatic TMPs >2 months after trauma were divided into an observation group (n = 18) and EGF group (n = 26). Patients in the EGF group underwent direct application of EGF without stripping of the perforation edge. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709183099
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http://dx.doi.org/10.1016/j.amjoto.2018.11.011DOI Listing
November 2018
2 Reads

A randomized, open-label, multicenter, comparative study of therapeutic efficacy, safety and tolerability of BNO 1030 extract, containing marshmallow root, chamomile flowers, horsetail herb, walnut leaves, yarrow herb, oak bark, dandelion herb in the treatment of acute non-bacterial tonsillitis in children aged 6 to 18 years.

Am J Otolaryngol 2018 Oct 24. Epub 2018 Oct 24.

Ivano-Frankivsk National Medical University, Galitskaya str. 2, 76000 Ivano-Frankivsk, Ukraine.

Seventy to 95% of acute tonsillitis episodes are caused by viral infection, therefore why antibiotic therapy is not indicated in majority of cases. In such cases, acetaminophen or ibuprofen are used to alleviate the symptoms. The objective of this study was assessment of efficacy of phytoneering extract BNO 1030 (Imupret®) in patients with acute non-bacterial tonsillitis. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.10.012DOI Listing
October 2018
1 Read

Titanium ossicular chain reconstruction in single stage canal wall down tympanoplasty for chronic otitis media with mucosa defect.

Am J Otolaryngol 2018 Nov 28. Epub 2018 Nov 28.

Department of Otology and Skull Base Surgery, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, China; NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai, China. Electronic address:

Purpose: To evaluate surgical outcomes for chronic otitis media with mucosa defect underwent titanium ossicular chain reconstruction (OCR) in single stage canal wall down tympanoplasty (CWD).

Methods: A clinical retrospective study was performed on 83 cases of the chronic otitis media with mucosa defect and 123 ears with mucosa integrity according to intraoperative findings that underwent synchronous titanium OCR in single stage CWD form January 2012 to January 2018. Pre- and postoperative air conduction threshold (AC), air-bone gap (ABG) and ABG closure at 0. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.11.012DOI Listing
November 2018
1 Read

Oral core-needle biopsy in the diagnosis of malignant parapharyngeal space tumors.

Am J Otolaryngol 2018 Nov 22. Epub 2018 Nov 22.

Department of Otolaryngology-Head and Neck, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Objective: To confirm the pre-treatment diagnosis of parapharyngeal space malignancy could aid the treatment plan.

Methods: For patients with suspected malignant parapharyngeal space tumors following preoperative imaging, oral biopsy was conducted for pathological diagnosis with the use of 22-G biopsy needles.

Results: A total of 11 patients were enrolled. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.11.005DOI Listing
November 2018
2 Reads

Computational fluid dynamics analysis of H-uvulopalatopharyngoplasty in obstructive sleep apnea syndrome.

Am J Otolaryngol 2018 Dec 6. Epub 2018 Dec 6.

The Department of Otolaryngology-Head and Neck Surgery, The First Hospital of Jilin University, Changchun, 130000, Jilin Province, China. Electronic address:

Purpose: To explore the impact of H-uvulopalatopharyngoplasty (H-UPPP) in obstructive sleep apnea syndrome (OSAS) and gain insights into the potential mechanism underlying improvement by H-UPPP.

Methods: In a cohort of 11 OSAS patients, computational fluid dynamics (CFD) models of the upper airway were obtained using commercial software from computed tomography (CT) datasets before and after H-UPPP. Morphological and numerical parameters were respectively computed and compared during the peak tidal inspiratory flow. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.12.001DOI Listing
December 2018
1 Read

Molecular and immunologic analysis of laryngeal squamous cell carcinoma in smokers and non-smokers.

Am J Otolaryngol 2018 Nov 22. Epub 2018 Nov 22.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.

Background: Laryngeal squamous cell carcinoma (LSCC) is strongly associated with tobacco use, but recent reports suggest an increasing incidence of LSCC in patients without traditional risk factors, suggesting an alternative etiology of tumorigenesis. The purpose of this study is to characterize this non-smoking population and to compare immunohistochemical markers in tumor specimens from non-smokers and smokers with LSCC.

Methods: A retrospective chart review of patients with LSCC at Johns Hopkins Hospital (JHH) was performed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709183088
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http://dx.doi.org/10.1016/j.amjoto.2018.11.009DOI Listing
November 2018
4 Reads

Cochlear implantation in patients with ossified cochleas.

Am J Otolaryngol 2018 Dec 8. Epub 2018 Dec 8.

Department of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan, China; NHC Key Laboratory of Otorhinolaryngology, Shandong University, Jinan, China. Electronic address:

Purpose: The timing of CI for postmeningitic deafness is controversial and differential outcomes have been reported. To review and share our surgical and auditory outcomes.

Materials And Methods: 17 patients with ossified cochleas who received CI were enrolled. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709183105
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http://dx.doi.org/10.1016/j.amjoto.2018.12.004DOI Listing
December 2018
7 Reads

The role of the otolaryngologist in the evaluation and management of headaches.

Am J Otolaryngol 2019 Jan - Feb;40(1):115-120. Epub 2018 Jul 7.

Department of Otolaryngology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, United States.

Background: Headaches are commonly evaluated in otolaryngology and often represent a diagnostic dilemma. This review addresses rhinogenic headache as well as trigeminal neuralgia and migraine, both of which can masquerade as sinus headache and whose management increasingly involves otolaryngology intervention. Discussion considers diagnostic criteria and novel therapies and derives an algorithm for clinical decision-making. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.07.002DOI Listing
July 2018
2 Reads

Stapes hypermobility as a possible cause of hyperacusis.

Am J Otolaryngol 2018 Oct 31. Epub 2018 Oct 31.

Ear Research Foundation, 1901 Floyd Street, Sarasota, FL 34239, United States of America.

Objective: Hyperacusis is a reduction of normal tolerances for everyday sounds. Although several publications have been produced demonstrating that minimally invasive surgical procedures may improve patient symptoms, the precise etiology of hyperacusis often remains elusive. This study describes 21 patients, 7 of whom stapes hypermobility is believed to be a mechanical genesis of their hyperacusis symptoms. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.10.018DOI Listing
October 2018
1 Read

Pyogenic granuloma of the larynx: A rare cause of hemoptysis.

Am J Otolaryngol 2018 Oct 29. Epub 2018 Oct 29.

Head and Neck Institute, Cleveland Clinic, Cleveland, OH, USA.

Pyogenic granuloma (PG) may involve gingival mucosa (granuloma gravidarum) in pregnancy but rarely involves the airway. This case report is perhaps the only reported presentation of PG in the larynx causing hemoptysis at a late stage of pregnancy. On laryngoscopic exam, a vascular, right false vocal fold neoplasm was identified with pathological characteristics consistent with PG. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.10.014DOI Listing
October 2018
2 Reads

Clinical features of laryngeal myasthenia gravis: A case series.

Am J Otolaryngol 2018 Nov 5. Epub 2018 Nov 5.

Department of Neurology, Tianjin Union Medical Center, Tianjin 300121, China.

Background: Myasthenia gravis (MG) is an autoimmune disease. Dysarthria, dysphagia, and difficulty swallowing as exclusive initial and primary complaints in MG (laryngeal MG) are rare and seldom reported.

Methods: Here we review and analyze the largest series of laryngeal MG patients. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.11.002DOI Listing
November 2018
2 Reads

Application of indocyanine green in the parathyroid detection and protection: Report of 3 cases.

Am J Otolaryngol 2018 Nov 7. Epub 2018 Nov 7.

The Second Department of General Surgery, Zhuhai People's Hospital, No. 79 of Kangning Road, Xiangzhou District, Zhuhai City, Guangdong Province 519000, China. Electronic address:

Background: It was thought that identifying the parathyroid gland during surgery was difficult for surgeons. It may be critical to locate the parathyroid for surgeons during thyroidectomy or parathyroidectomy due to the significant function of the parathyroid in calcium balance. According to recent reports, intrinsic fluorescence of the parathyroid has been found. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.11.003DOI Listing
November 2018
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Vascular malformation of the sphenoid and temporal bone: A diagnostic dilemma.

Am J Otolaryngol 2018 Sep 18. Epub 2018 Sep 18.

Department of Otolaryngology - Head & Neck Surgery, Emory University, Medical Office Tower (MOT), 9th Floor, 550 Peachtree Street NE, Atlanta, GA 30308, United States of America. Electronic address:

We present a rare case of a vascular anomaly of the sphenoid and temporal bones causing an expandable mass of the temporal region with dependent patient positioning and characteristic osseous changes on imaging. Initial diagnosis considerations included multiple myeloma (MM), fibrous dysplasia (FD), Paget's disease, lymphoma, meningoencephalocele (MEC), and vascular malformation (VaM). VaMs of the head and neck are rare and typically arise in the mandible and maxilla. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709183085
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http://dx.doi.org/10.1016/j.amjoto.2018.09.013DOI Listing
September 2018
10 Reads

Clinical efficacy of cognitive behavioral therapy for chronic subjective tinnitus.

Am J Otolaryngol 2018 Oct 29. Epub 2018 Oct 29.

Department of Otorhinolaryngology, Shanghai Tongren Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200336, China.

Background: Although cognitive behavioral therapy (CBT) has been known with a theoretical basis for tinnitus patients, there still were lack of clinical evidence.

Objective: To evaluate the clinical efficacy of cognitive behavioral therapy (CBT) for treatment of chronic subjective tinnitus.

Methods: One hundred patients with chronic subjective tinnitus patients were randomly divided into control (50 cases) and intervention (50 cases) groups, which received the masking therapy and sound treatment and masking therapy and sound treatment plus CBT. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.10.017DOI Listing
October 2018
18 Reads

Important factor for pain relief in patients with eagle syndrome: Excision technique of styloid process.

Authors:
Fatma Caylakli

Am J Otolaryngol 2018 Oct 21. Epub 2018 Oct 21.

Baskent University School of Medicine, Otorhinolaryngology Head and Neck Surgery Department, Ankara, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.amjoto.2018.10.009DOI Listing
October 2018
5 Reads

MTHFR AND ApoE genetic variants association with sudden sensorineural hearing loss.

Am J Otolaryngol 2018 Oct 29. Epub 2018 Oct 29.

Otorhinolaryngology Research Center, Amir-Alam Hospital, Department of Otolaryngology-Head and Neck Surgery, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Hypothesis: Although the pathogenesis of sudden sensorineural hearing loss (SSNHL) is not clear, however several causes including genetic factors seems to be implicated. We hypothesized that common genetic variants might be involved in SSNHL.

Background: SSNHL is known to be an idiopathic disease because the causative factors have not been identified. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.10.015DOI Listing
October 2018
1 Read
1.080 Impact Factor

Letter to the editor: Effect of changing postoperative pain management on bleeding rates in tonsillectomy patients.

Authors:
Zhengcai Lou

Am J Otolaryngol 2018 Sep 30. Epub 2018 Sep 30.

Department of Otorhinolaryngology, the affiliated Yiwu Hospital, Yiwu City, 322000, Zhejiang Province, China. Electronic address:

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http://dx.doi.org/10.1016/j.amjoto.2018.09.020DOI Listing
September 2018
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Update on the diagnostic considerations for neurogenic nasal and sinus symptoms: A current review suggests adding a possible diagnosis of migraine.

Am J Otolaryngol 2018 Oct 2. Epub 2018 Oct 2.

Headache Medicine, Yale Neuroscience Center, New Haven, CT, USA. Electronic address:

Background: Treatment of rhinosinusitis (RS) is one of the leading reasons for prescriptions of antibiotics, although they often fail to provide symptomatic relief. Appropriately diagnosing and treating patients presenting with RS for whom antibiotic therapy has failed or who have normal CT findings is a controversial topic. One explanation is that what these patients are experiencing is misinformation from the trigeminal nerve and autonomic nervous system. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709183087
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http://dx.doi.org/10.1016/j.amjoto.2018.09.021DOI Listing
October 2018
7 Reads

Audiological outcomes in sudden sensorineural hearing loss with presumed inner ear hemorrhage.

Am J Otolaryngol 2018 Sep 26. Epub 2018 Sep 26.

Department of Otorhinolaryngology, The First Affiliated Hospital, Sun Yat-sen University and Institute of Otorhinolaryngology, Sun Yat-sen University, Guangzhou 510080, PR China. Electronic address:

Objective: To explore the hearing outcomes and prognostic factors in patients with sudden sensorineural hearing loss resulting from inner ear hemorrhage.

Methods: 42 patients (22 male and 20 female) were recruited from January 2016 to December 2017. Intravenous methylprednisolone and/or intratympanic corticosteroid were used as salvage therapy. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.09.017DOI Listing
September 2018
3 Reads

The pedicled levator labii superioris alaeque nasi flap: A durable single-stage option for reconstruction of full-thickness nasal defects.

Am J Otolaryngol 2018 Oct 2. Epub 2018 Oct 2.

Geisinger Health System, United States of America.

Importance: Repair of full-thickness nasal defects can often be associated with multi-stage operations that can result in significant physical and psychological morbidity for patients. We present a single-stage option for reconstruction of these defects.

Objective: Demonstrate the utility of the pedicled levator labii superioris alaeque nasi flap and consistency of its vascular pedicle. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.09.015DOI Listing
October 2018
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Diagnostic accuracy of F-18 FDG PET or PET/CT for detection of lymph node metastasis in clinically node negative head and neck cancer patients; A systematic review and meta-analysis.

Am J Otolaryngol 2018 Oct 23. Epub 2018 Oct 23.

Department of Nuclear Medicine, Pusan National University Hospital, Busan, Republic of Korea.

Objective: The purpose of the current study was to investigate the diagnostic performance of F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) or positron emission tomography/computed tomography (PET/CT) for the detection of cervical lymph node (LN) metastasis in clinically node negative head and neck squamous cell cancer (cN0 HNSCC) patients through a systematic review and meta-analysis.

Methods: The PubMed and EMBASE database, from the earliest available date of indexing through April 30, 2018, were searched for studies evaluating the diagnostic performance of F-18 FDG PET or PET/CT for the detection of LN metastasis in cN0 HNSCC patients. We determined the sensitivities and specificities across studies, calculated positive and negative likelihood ratios (LR+ and LR-), and constructed summary receiver operating characteristic (SROC) curves. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.10.013DOI Listing
October 2018
8 Reads

Poorly differentiated plasmacytoid squamous cell carcinoma: Case report of a rare malignancy.

Am J Otolaryngol 2019 Jan - Feb;40(1):124-128. Epub 2018 Oct 23.

Case Western Reserve University School of Medicine, 10900 Euclid Avenue, Cleveland, OH 44106, USA; Department of Otolaryngology - Head & Neck Surgery, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, OH 44109, USA. Electronic address:

Plasmacytoid squamous cell carcinoma is an especially aggressive variant of squamous cell carcinoma that has previously been described in the literature as a variant of oral cancers and most extensively, in vulvular [3], transitional cell, and urothelial carcinomas [2,13,15-20]. In this case report, we present a 36-year-old man with 6 to 8 weeks of a progressively enlarging mass over the lateral third of his clavicle, acromion process, and deltoid. The mass was resected, and the supraclavicular defect was reconstructed using an anterolateral thigh free flap. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.10.005DOI Listing
October 2018
2 Reads

Analysis of the role of thyroidectomy and thymectomy in the surgical treatment of secondary hyperparathyroidism.

Am J Otolaryngol 2019 Jan - Feb;40(1):67-69. Epub 2018 Oct 22.

Division of Head and Neck Surgery, Department of Ophthalmology, Otolaryngology, Head and Neck Surgery, Ribeirao Preto Medical School, University of Sao Paulo, Brazil. Electronic address:

Purpose: Parathyroidectomy can be subtotal or total with an autograft for the treatment of renal hyperparathyroidism. In both cases, it may be extended with bilateral thymectomy and total or partial thyroidectomy. Thymectomy may be recommended in combination with parathyroidectomy in order to prevent mediastinal recurrence. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709183075
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http://dx.doi.org/10.1016/j.amjoto.2018.10.010DOI Listing
October 2018
7 Reads

Patient preferences regarding the communication of biopsy results in the general otolaryngology clinic.

Am J Otolaryngol 2019 Jan - Feb;40(1):83-88. Epub 2018 Oct 7.

Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, 801 Welch Road, Stanford, CA 94305-1611, United States of America. Electronic address:

Objectives: To determine the preferred methods of communicating biopsy results for patients in our comprehensive otolaryngology clinic, and to examine factors associated with preferring remote vs. in-person communication of results.

Study Design: Cross-sectional study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960709183090
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http://dx.doi.org/10.1016/j.amjoto.2018.10.002DOI Listing
October 2018
10 Reads