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    5179 results match your criteria American Journal of Infection Control[Journal]

    1 OF 104

    A new frontier: Central line-associated bloodstream infection surveillance in home infusion therapy.
    Am J Infect Control 2018 Jun 13. Epub 2018 Jun 13.
    Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; Armstrong Institute of Patient Safety and Quality, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Hospital Epidemiology and Infection Control, Johns Hopkins Hospital, Baltimore, MD.

    High-risk Staphylococcus aureus transmission in the operating room: A call for widespread improvements in perioperative hand hygiene and patient decolonization practices.
    Am J Infect Control 2018 Jun 12. Epub 2018 Jun 12.
    Department of Anesthesiology, University of Iowa Hospitals and Clinics, Iowa City, IA.
    Background: Increased awareness of the epidemiology of transmission of pathogenic bacterial strain characteristics may help to improve compliance with intraoperative infection control measures. Our aim was to characterize the epidemiology of intraoperative transmission of high-risk Staphylococcus aureus sequence types (STs).

    Methods: S aureus isolates collected from 3 academic medical centers underwent whole cell genome analysis, analytical profile indexing, and biofilm absorbance. Read More

    Identification of surgical site infections using electronic health record data.
    Am J Infect Control 2018 Jun 12. Epub 2018 Jun 12.
    Surgical Outcomes and Applied Research Program, University of Colorado School of Medicine, Aurora, CO; Department of Surgery, University of Colorado School of Medicine, Aurora, CO.
    Background: The objective of this study was to develop an algorithm for identifying surgical site infections (SSIs) using independent variables from electronic health record data and outcomes from the American College of Surgeons National Surgical Quality Improvement Program to supplement manual chart review.

    Methods: We fit 3 models to data from patients undergoing operations at the University of Colorado Hospital between 2013 and 2015: a similar model reported previously in the literature, a comprehensive model with 136 possible predictors, and a combination of those. All models used a generalized linear model with a lasso penalty. Read More

    Efficacy of bladder irrigation in preventing urinary tract infections associated with short-term catheterization in comatose patients: A randomized controlled clinical trial.
    Am J Infect Control 2018 Jun 11. Epub 2018 Jun 11.
    Modeling of Noncommunicable Disease Research Center, Department of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
    Background: Bladder irrigation can be performed to prevent catheter-associated urinary tract infections (CAUTI), but its efficacy has been not reported in short-term indwelling urinary catheterization. This clinical trial aimed to examine the efficacy of bladder irrigation with normal saline solution in preventing CAUTI in comatose patients admitted to intensive care units.

    Materials And Methods: Eligible patients were randomized to the experimental group or control group. Read More

    Patient- and hospital-level predictors of vancomycin-resistant Enterococcus (VRE) bacteremia in Ontario, Canada.
    Am J Infect Control 2018 Jun 11. Epub 2018 Jun 11.
    Public Health Ontario, Toronto, ON, Canada; Department of Medicine, University of Toronto, Toronto, ON, Canada; Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
    Background: Data are limited on risk factors for vancomycin-resistant Enterococcus (VRE) bacteremia.

    Methods: All patients with a confirmed VRE bacteremia in Ontario, Canada, between January 2009 and December 2013 were linked to provincial healthcare administrative data sources and frequency matched to 3 controls based on age, sex, and aggregated diagnosis group. Associations between predictors and VRE bacteremia were estimated by generalized estimating equations and summarized using odds ratios (ORs) and corresponding 95% confidence intervals (CIs). Read More

    State health department validations of central line-associated bloodstream infection events reported via the National Healthcare Safety Network.
    Am J Infect Control 2018 Jun 11. Epub 2018 Jun 11.
    National Healthcare Safety Network, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA.
    Background: Numerous state health departments (SHDs) have validated central line-associated bloodstream infection (CLABSI) data, and results from these studies provide important insights into the accuracy of CLABSI reporting to the National Healthcare Safety Network (NHSN) and remediable shortcomings in adherence to the CLABSI definition and criteria.

    Methods: State CLABSI validation results were obtained from peer-reviewed publications, reports on SHD Web sites, and via personal communications with the SHD health care-associated infections coordinator. Data accuracy measures included pooled mean sensitivity, specificity, positive predictive value, and negative predictive value. Read More

    Creation of a competency-based professional development program for infection preventionists guided by the APIC Competency Model: steps in the process.
    Am J Infect Control 2018 Jun 7. Epub 2018 Jun 7.
    Mohawk Valley Health System; Faxton St. Luke's Healthcare, St. Elizabeth's Medical Center Infection Prevention Departments, Utica, NY.
    Background: Infection Preventionists have varying levels of educational preparation. Many have no prior experience in IP. The diversity makes design of professional development programs challenging. Read More

    Predictors of certification in infection prevention and control among infection preventionists: APIC MegaSurvey findings.
    Am J Infect Control 2018 Jun 6. Epub 2018 Jun 6.
    APIC MegaSurvey Project, Arlington, VA.
    Background: The 2015 APIC MegaSurvey was completed by 4,078 members to assess infection prevention practices. This study's purpose was to examine MegaSurvey results to relate infection preventionist (IP) certification status with demographic characteristics, organizational structure, compensation benefits, and practice and competency factors.

    Methods: Descriptive statistics were used to examine population characteristics and certification status. Read More

    Efficacy and safety of a novel skin cleansing formulation versus chlorhexidine gluconate.
    Am J Infect Control 2018 Jun 5. Epub 2018 Jun 5.
    Institute for Wound Research, University of Florida, Gainesville, FL.
    Background: This study evaluated whether a multi-ingredient surfactant colloidal silver technology was noninferior to a 4% chlorhexidine gluconate (CHG) antiseptic on immediate and persistent antimicrobial activity.

    Methods: The inguinal regions of 81 healthy adults were demarcated into 4 quadrants, and 3 were used for testing each product at baseline, 10 minutes, and 6 hours postapplication. The log of the number of colony forming units was obtained using a cylinder sampling technique. Read More

    Development of a risk prediction model of carbapenem-resistant Enterobacteriaceae colonization among patients in intensive care units.
    Am J Infect Control 2018 Jun 5. Epub 2018 Jun 5.
    College of Nursing, Pusan National University, Yangsan, Republic of Korea. Electronic address:
    Background: Few hospitals have conducted surveillance cultures to identity carbapenem-resistant Enterobacteriaceae (CRE) colonization in Korea because of high test costs, long wait time to get results, and lack of personnel. This study aimed to identify risk factors of CRE colonization and to develop a model for predicting the risk of CRE colonization.

    Methods: This retrospective cohort study was done with medical record review at a tertiary hospital between October 1, 2016, and October 31, 2017, in 444 adult patients admitted to the intensive care unit. Read More

    What variables are associated with the public's willingness to take measures to maintain a hygienic hospital environment?
    Am J Infect Control 2018 Jun 5. Epub 2018 Jun 5.
    Bnai Zion Medical Center, Haifa, Israel.
    Background: Most of the studies on hospital infections have focused on the perceptions and reported behavior of the medical personnel. This research explore the practices undertaken both by Israeli patients and visitors, in order to maintain a hygienic hospital environment, and to locate the variables that are associated with them.

    Methods: An online survey of national representative sample of Israeli hospital's visitors and patients adult population, who were hospitalized in the five years before the interview (n=209), and who visited patients in hospitals in the three years before the interview (n=454). Read More

    Exploring the use of entertainment-education YouTube videos focused on infection prevention and control.
    Am J Infect Control 2018 Jun 5. Epub 2018 Jun 5.
    School of Public Health and Community Medicine, University of New South Wales, Sydney, NSW, Australia. Electronic address:
    Background: As a communications strategy, education entertainment has been used to inform, influence, and shift societal and individual behaviors. Recently, there has been an increasing number of entertainment-education YouTube videos focused on hand hygiene. However, there is currently no understanding about the quality of these videos; therefore, this study aimed to explore the social media content and user engagement with these videos. Read More

    Severe sepsis 3-hour bundle compliance and mortality.
    Am J Infect Control 2018 Jun 5. Epub 2018 Jun 5.
    BayCare Health System, Clearwater, FL.
    Severe sepsis is a major cause of mortality among hospitalized patients. We tracked severe sepsis 3-hour bundle compliance and mortality over time. Those patients with severe sepsis who received the entire bundle had improved in-hospital survivability over those patients who did not receive the bundle. Read More

    Factors affecting annual compensation and professional development support for infection preventionists: Implications for recruitment and retention.
    Am J Infect Control 2018 Jun 4. Epub 2018 Jun 4.
    Denver Health Medical Center, Denver, CO.
    Background: Factors affecting annual compensation and professional development support have been studied for various healthcare professions. However, there is little understanding of these factors for infection preventionists (IPs).

    Methods: Using secondary data from the Association for Professionals in Infection Control and Epidemiology 2015 MegaSurvey, we designed a descriptive, correlational study to describe IP annual compensation and professional development support. Read More

    Needleless connector drying time-how long does it take?
    Am J Infect Control 2018 Jun 5. Epub 2018 Jun 5.
    Alliance for Vascular Access Teaching & Research (AVATAR) Group, Menzies Health Institute Queensland, School of Nursing and Midwifery, Griffith University, Brisbane, Australia.
    Allowing needleless connectors (NCs) on vascular catheters adequate drying time after cleaning with antiseptic is essential. Drying time instructions on antiseptic pads/wipes relate to skin use, not inanimate objects. Needleless connector drying times after a 15-second scrub with isopropyl-alcohol, isopropyl-alcohol/chlorhexidine, or povidone-iodine varied from 5 seconds to >6 minutes. Read More

    To check or not to check. Rectal ESBL colonization in hospitalized elderly patients.
    Am J Infect Control 2018 Jun 1. Epub 2018 Jun 1.
    The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Shmuel Harofe Geriatric Medical Center, Beer Yaakov, Israel. Electronic address:
    Background: The worldwide spread of extended-spectrum-beta-lactamase (ESBL) producing bacteria has affected health care. ESBL confers resistance to the majority of beta-lactam antibiotics.

    Materials And Methods: We intended to quantify the rates of rectal ESBL-positive and negative patients that eventually developed fever and urinary tract infection (UTI). Read More

    Factors for compliance with infection control practices in home healthcare: findings from a survey of nurses' knowledge and attitudes toward infection control.
    Am J Infect Control 2018 Jun 1. Epub 2018 Jun 1.
    Columbia University School of Nursing, New York, NY.
    Background: Infection is a leading cause of hospitalization among home healthcare patients. Nurses play an important role in reducing infection among home healthcare patients by complying with infection control procedures. However, few studies have examined the compliance of home healthcare nurses with infection control practices or the range of sociocultural and organizational factors that may be associated with compliance. Read More

    Ultrasound probe use and reprocessing: Results from a national survey among U.S. infection preventionists.
    Am J Infect Control 2018 Jun 1. Epub 2018 Jun 1.
    University of Louisville Global Health Program, Division of Infectious Diseases, University of Louisville School of Medicine, Louisville, KY.
    Background: Improper infection prevention practice associated with ultrasound probe use has been linked to increased infection risk, outbreaks, and death. Although guidelines for reprocessing and use of probes exist, it is unclear how extensively these have been adopted in practice.

    Methods: Infection preventionists from U. Read More

    Infection prevention staffing and resources in U.S. acute care hospitals: Results from the APIC MegaSurvey.
    Am J Infect Control 2018 Jun 1. Epub 2018 Jun 1.
    Denver Health Medical Center, Department of Patient Safety and Quality, Denver, CO.
    Background: Given the changing nature of infection prevention and control (IPC), appropriate infection preventionist (IP) staffing needs to be established. In this study, we aimed to describe current IP staffing levels and IPC department resources in U.S. Read More

    Revisiting the Association for Professionals in Infection Control and Epidemiology Competency Model for the Infection Preventionist: An evolving conceptual framework.
    Am J Infect Control 2018 Jun 1. Epub 2018 Jun 1.
    Association for Professionals in Infection Control and Epidemiology Inc., Arlington, VA.
    This article reviews 2 models of skill acquisition, 1 from nursing and the other from aviation, and compares them to the Association for Professionals in Infection Control and Epidemiology Competency Model for the Infection Preventionist (IP). The authors explore the mental activity associated with competence and provide usable examples for IPs to further assess their own competence, and competence of IPs in their charge. This was done for the purpose of advancing and expanding upon the career stages within the field of infection prevention. Read More

    Long-sleeved medical workers' coats and their microbiota.
    Am J Infect Control 2018 May 31. Epub 2018 May 31.
    Division of Hygiene and Medical Microbiology, Medical University Innsbruck, Innsbruck, Austria. Electronic address:
    In this study we aimed to assess the contamination rate of long-sleeved medical workers' coats (N = 100) in a point-prevalence study. Ninety-one percent of the coats were contaminated with normal human flora, but only the minority (9%) showed presence of pathogenic non-multiresistant bacteria. The data of this study may implicate that long-sleeved coats harbor low risk for the treated patients to be contaminated with pathogenic bacteria during medical consultation. Read More

    An evaluation of provider-chosen antibiotic indications as a targeted antimicrobial stewardship intervention.
    Am J Infect Control 2018 May 31. Epub 2018 May 31.
    Department of Pharmacy, Johns Hopkins Bayview Medical Center, Baltimore, MD.
    Background: Provider-entered indications for antibiotics have been recommended as a tracking tool for antibiotic stewardship programs. The accuracy and utility of these indications are unknown.

    Methods: Drug-specific lists of evidence-based indications were integrated into an electronic health system as an ordering hard-stop. Read More

    Possible pseudotransmission of Enterobacter cloacae associated with an endobronchial ultrasound scope.
    Am J Infect Control 2018 May 30. Epub 2018 May 30.
    Providence St Peter Hospital, Olympia, WA.
    During an investigation of positive environmental cultures with Enterobacter cloacae from an endobronchial ultrasound scope, possible pseudotransmission was discovered between 2 patients. All reprocessing steps were adhered to and the original equipment manufacture's quality control assessment of the scope could not determine the root cause. Our findings appear to be the first documented case of pseudotransmission from an endobronchial ultrasound scope and suggest bacterial transmission may exist in endoscopes without an elevator channel. Read More

    Septic arthritis due to oral streptococci following intra-articular injection: A case series.
    Am J Infect Control 2018 May 24. Epub 2018 May 24.
    Department of Medicine, University of Virginia Health System, Charlottesville, VA; Division of Infectious Diseases & International Health, Department of Medicine, University of Virginia Health System, Charlottesville, VA.
    Oral streptococcal species are a rare cause of septic arthritis. We describe 4 cases of septic arthritis due to oral streptococcal species following joint injection. The routine use of face masks during joint injection may prevent this rare but serious complication. Read More

    Investigating the effect of preparation for and participation in a hand-sanitizing relay on nursing students' ability to recall the WHO 6-step hand hygiene technique.
    Am J Infect Control 2018 May 24. Epub 2018 May 24.
    Safeguarding Health through Infection Prevention (SHIP) Research Group, School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, UK.
    This study explored whether preparation for a hand-sanitizing relay affected nursing students' ability to recall, 12 months later, the World Health Organization 6-step hand hygiene technique. No significant difference was observed in recall between those who participated in the relay and those who did not (P = .736). Read More

    Achieving balance between implementing effective infection prevention and control practices and maintaining a home-like setting in U.S. Department of Veterans Affairs nursing homes.
    Am J Infect Control 2018 May 24. Epub 2018 May 24.
    National Infectious Diseases Service, Office of Specialty Care Services, Department of Veterans Affairs, Cincinnati, OH; Cincinnati VA Medical Center, Cincinnati, OH; University of Cincinnati College of Medicine, Cincinnati, OH.
    Nursing homes present a unique challenge for implementing infection prevention and control practices while striving to maintain a home-like environment. Medical devices such as urinary catheters and central venous catheters have become a part of nursing home care but can predispose residents to associated infections. Because evidence-based prevention bundles were implemented, catheter-associated urinary tract infections (CAUTIs) and central line-associated bloodstream infections (CLABSIs) were monitored in all U. Read More

    Multisite evaluation of environmental cleanliness of high-touch surfaces in intensive care unit patient rooms.
    Am J Infect Control 2018 May 23. Epub 2018 May 23.
    St Boniface Research Centre and University of Manitoba, Winnipeg, Manitoba, Canada.
    The efficacy of discharge cleaning and disinfection of high-touch surfaces of intensive care unit patient rooms in Brazil, Canada, the Netherlands, and the United States was evaluated and the effect of an educational intervention was determined. Significant site-to-site differences in cleaning regimens and baseline cleanliness levels were observed using ATP levels, colony-forming units, and reflective surface marker removal percent pass rates. An educational intervention that includes rapid feedback of the ATP measurements could significantly improve the quality of the cleaning and disinfection regimens. Read More

    Influenza vaccine coverage and predictive factors associated with influenza vaccine uptake among pediatric patients.
    Am J Infect Control 2018 May 23. Epub 2018 May 23.
    School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
    Background: Despite recommendations from health care authorities, reports of severe influenza occur yearly among unvaccinated infants and children.

    Objectives: This study investigated influenza vaccine coverage and predictive factors for vaccination status among pediatric patients during the 2016-2017 winter influenza season.

    Methods: A cross-sectional survey was conducted among parents of our study population identified through a major pediatric outpatient clinic in Hong Kong. Read More

    Evaluation of the antimicrobial efficacy and skin safety of a novel color additive in combination with chlorine disinfectants.
    Am J Infect Control 2018 May 23. Epub 2018 May 23.
    Department of Biomedical Engineering, Columbia University, New York, New York.
    Objective: A novel color additive colorizes chlorine disinfectants blue to improve visibility and enhance spray surface coverage, and it fades to colorless to indicate elapsed contact time. We investigated its interactions with 3 chlorine disinfectants to determine if the additive would adversely affect the disinfectants' antimicrobial efficacy or skin safety.

    Methods: We tested 0. Read More

    Health care worker perceptions toward computerized clinical decision support tools for Clostridium difficile infection reduction: A qualitative study at 2 hospitals.
    Am J Infect Control 2018 May 23. Epub 2018 May 23.
    Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD.
    Background: Clostridium difficile infection (CDI) is associated with significant morbidity and mortality. Computerized clinical decision support (CCDS) tools can aid process improvement in infection prevention and antibiotic stewardship, but implementation and health care workers (HCWs) uptake of these tools is often variable. The objective of this study was to describe HCWs' perceptions of barriers and facilitators related to uptake of CCDS tools as part of a CDI reduction bundle. Read More

    Predictors for gut colonization of carbapenem-resistant Enterobacteriaceae in neonates in a neonatal intensive care unit.
    Am J Infect Control 2018 Jun;46(6):e31-e35
    Department of Microbiology, UCMS & GTB Hospital, New Delhi, India.
    Background: With the emergence of carbapenem-resistant isolates, the therapeutic alternatives have become limited. Various factors are responsible for carbapenem-resistant Enterobacteriaceae (CRE) gut colonization. This study was conducted to determine predictors for CRE gut colonization in neonates who were hospital delivered and admitted in a neonatal intensive care unit (NICU). Read More

    A microbiological study to investigate the carriage and transmission-potential of Clostridium difficile spores on single-use and reusable sharps containers.
    Am J Infect Control 2018 May 22. Epub 2018 May 22.
    Levine Cancer Institute, Carolinas HealthCare System, Charlotte, NC.
    Background: A 2015 study matching use of disposable and reusable sharps containers (DSCs, RSCs) with Clostridium difficile infection (CDI) incidence found a decreased incidence with DSCs. We conducted microbiologic samplings and examined the literature and disease-transmission principles to evaluate the scientific feasibility of such an association.

    Methods: (i) 197 RSCs were sampled for C. Read More

    Adenovirus pseudo-outbreak in a large UK neonatal intensive care unit.
    Am J Infect Control 2018 May 21. Epub 2018 May 21.
    Cambridge Clinical Microbiology and Public Health Laboratory, Department of Clinical Virology, CMPHL level 6, Addenbrooke's Hospital, Cambridge, UK.
    An unusually high number of positive adenovirus stool antigen tests were observed in neonatal samples from a large tertiary referral unit over a 10-week period, prompting the declaration of an outbreak and escalation of infection control precautions. Subsequent testing of original samples by alternative methods revealed a series of false-positive results. This is the first adenovirus pseudo-outbreak to be reported in the United Kingdom and the first to involve the Proflow Rotavirus-Adenovirus Combi test. Read More

    Use of adenosine triphosphate to audit reprocessing of flexible endoscopes with an elevator mechanism.
    Am J Infect Control 2018 May 21. Epub 2018 May 21.
    Department of Gastroenterology, Loyola University Medical Center, Maywood, IL. Electronic address:
    Background: There have been reported outbreaks of carbapenem-resistant Enterobacteriaceae infections linked to endoscopes with elevator mechanisms. Adenosine triphosphate (ATP) testing has been used as a marker for bioburden and monitoring manual cleaning for flexible endoscopes with and without an elevator mechanism. The objective of this study was to determine whether routine ATP testing could identify areas of improvement in cleaning of endoscopes with an elevator mechanism. Read More

    Hand hygiene adherence in relation to influenza season during 6 consecutive years.
    Am J Infect Control 2018 May 18. Epub 2018 May 18.
    Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
    Hand hygiene (HH) is the single most important measure in reducing the burden of healthcare-acquired infections. Based on 12,740 HH opportunities observed during 6 consecutive years at our tertiary care center, HH adherence among healthcare workers (HCWs) was significantly better during influenza season compared to non-influenza periods, after controlling for important covariables (odds ratio = 1.17, 95% confidence interval 1. Read More

    Enacting high reliability principles while caring for people with Ebola Virus Disease.
    Am J Infect Control 2018 May 18. Epub 2018 May 18.
    Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA.
    Background: Fear surrounds Ebola Virus Disease (EVD) because it is highly infectious. Yet members of the Serious Communicable Diseases Unit (SCDU) at Emory University Hospital (EUH) had to overcome that fear when caring for patients with EVD.

    Purpose: The analysis reported here illustrates how the members of EUH's SCDU tacitly enacted high reliability (HR) principles while caring for patients with EVD. Read More

    Evaluation of adenosine triphosphate test for cleaning assessment of gastroscopes and the effect on workload in a busy endoscopy center.
    Am J Infect Control 2018 May 18. Epub 2018 May 18.
    St. Boniface Research Centre, Winnipeg, MB, Canada.
    Objective: Using adenosine triphosphate (ATP) tests to assess manual cleaning of gastroscopes and to determine the associated workload in a busy endoscopy unit.

    Methods: Patient-used gastroscopes were sampled before and after cleaning to assess ATP levels, bioburden, and protein. Samples were collected by flushing 20 mL of sterile water through the biopsy port to the distal end. Read More

    Effect of methicillin-resistant Staphylococcus aureus in Japan.
    Am J Infect Control 2018 May 18. Epub 2018 May 18.
    Department of Healthcare Economics and Quality Management, Graduate School of Medicine, Kyoto University, Kyoto City, Kyoto, Japan. Electronic address:
    Background: Methicillin-resistant Staphylococcus aureus (MRSA) is the most common antimicrobial-resistant organism identified in Japanese health care facilities. This study analyzed the clinical and economic burdens attributable to methicillin resistance in S aureus in Japanese hospitals.

    Methods: We retrospectively investigated data from 14,905 inpatients of 57 hospitals combined with data from nosocomial infection surveillance and administrative claim databases. Read More

    Do WiFi-based hand hygiene dispenser systems increase hand hygiene compliance?
    Am J Infect Control 2018 May 17. Epub 2018 May 17.
    Division of Infection Control and Infectious Diseases, University Aachen, RWTH, Aachen, Germany.
    Innovative methods to ensure better compliance in hand hygiene are urgently needed. The aim of this study was to determine if WiFi-based hand hygiene dispenser-driven self-assessment systems (Wireless Fidelity, WiFi-dispenser) can support the work of infection control teams. Our results suggest that the continuous monitoring of dispenser usage can be a valuable addition to infection prevention and control programs, when used in a bundle in combination with conventional hand hygiene training. Read More

    Use patterns and frequency of hand hygiene in healthcare facilities: Analysis of electronic surveillance data.
    Am J Infect Control 2018 May 17. Epub 2018 May 17.
    Research, Development and Engineering, Ecolab, Eagan, MN.
    Background: Healthcare workers perform hand hygiene much more frequently than workers in other fields. As a result, healthcare workers have a higher exposure to topical antiseptic products.

    Methods: Five tertiary care facilities were equipped with an electronic hand hygiene compliance monitoring system. Read More

    Prevalence of infections and antimicrobial prescribing in Australian aged care facilities: Evaluation of modifiable and nonmodifiable determinants.
    Am J Infect Control 2018 May 18. Epub 2018 May 18.
    Victorian Healthcare Associated Infection Surveillance System Co-ordinating Centre, Melbourne, VIC, Australia.
    Background: Infections in aged care residents are associated with poor outcomes, and inappropriate antimicrobial prescribing contributes to adverse events, such as the emergence of antimicrobial resistance. The objective of this study was to identify resident- and facility-level factors associated with infection and antimicrobial prescribing in Australian aged care residents.

    Methods: Using data captured by a national point-prevalence survey (the Aged Care National Antimicrobial Prescribing Survey), risk and protective factors were determined by multivariate Poisson regression. Read More

    How to better monitor and clean irregular surfaces in operating rooms: Insights gained by using both ATP luminescence and RODAC assays.
    Am J Infect Control 2018 May 17. Epub 2018 May 17.
    UCLA Fielding School of Public Health, Department of Environmental Health Sciences, Los Angeles, CA; Division of Infectious Disease, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA. Electronic address:
    Background: A major limitation to developing evidence-based approaches to infection prevention is the paucity of real-time, quantitative methods for monitoring the cleanliness of environmental surfaces in clinical settings. One solution that has been proposed is adenosine triphosphate (ATP) bioluminescence assays, but this method does not provide information about the source of the ATP.

    Materials/methods: To address this gap, we conducted a study in which ATP bioluminescence was coupled with traditional RODAC sampling and matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry to assess which organisms were viable and present. Read More

    Lack of improvement in antimicrobial prescribing after a diagnosis of Clostridium difficile and impact on recurrence.
    Am J Infect Control 2018 May 17. Epub 2018 May 17.
    Infectious Diseases Section, VA Greater Los Angeles Healthcare System, Los Angeles, CA; Infectious Diseases Division, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA. Electronic address:
    Background: Antimicrobial use is one of the largest modifiable risk factors for development of Clostridium difficile infection (CDI). We sought to determine if a recent diagnosis of CDI affected the appropriateness of subsequent antimicrobial prescribing.

    Methods: This study is a retrospective electronic chart review of the Greater Los Angeles Veterans Administration. Read More

    State-level adoption of national guidelines for norovirus outbreaks in health care settings.
    Am J Infect Control 2018 May 16. Epub 2018 May 16.
    Department of Biomedical Informatics, School of Medicine, University of Utah, Salt Lake City, UT; Medical Informatics, Intermountain Healthcare, Salt Lake City, UT.
    Background: Clinical decision support (CDS) systems can help investigators use best practices when responding to outbreaks, but variation in guidelines between jurisdictions can make such systems hard to develop and implement. This study aimed to identify (1) the extent to which state-level guidelines adhere to national recommendations for norovirus outbreak response in health care settings and (2) the impact of variation between states on outbreak outcomes.

    Methods: State guidelines were obtained from Internet searches and direct contact with state public health officials in early 2016. Read More

    Enhanced central venous catheter bundle for pediatric parenteral-dependent intestinal failure.
    Am J Infect Control 2018 May 16. Epub 2018 May 16.
    Infection Prevention & Control, Boston Children's Hospital, Boston, MA; Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA.
    Background: Central line-associated bloodstream infections (CLABSIs) cause substantial morbidity and increase antimicrobial use and length of stay among hospitalized children in the United States. CLABSI occurs more frequently among high-risk pediatric patients, such as those with intestinal failure (IF) who are parenteral nutrition (PN) dependent. Following an increase in CLABSI rates, a quality improvement (QI) initiative was implemented. Read More

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