426,298 results match your criteria American Journal of Hospice & Palliative Medicine[Journal]

Real-world burden of systemic lupus erythematosus in the USA: a comparative cohort study from the Medical Expenditure Panel Survey (MEPS) 2016-2018.

Lupus Sci Med 2022 May;9(1)

US Evidence, AstraZeneca Pharmaceuticals LP, Wilmington, Delaware, USA.

Objective: SLE is a chronic, multiorgan, autoimmune disease; however, current prevalence estimates are dated and often from non-generalisable patient populations, and quality of life and patient-reported outcomes in the real-world SLE population are not well-published. The present study used the Medical Expenditure Panel Survey (MEPS), a generalisable US data source encompassing a representative sample of regions/payers, to estimate SLE prevalence and characterise disease burden compared with non-SLE respondents.

Methods: Retrospective population-based survey data weighted to the full US population from MEPS for the calendar years 2016-2018, pooled over the full study period, was used. Read More

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Detection of SARS-CoV-2 contamination in the operating room and birthing room setting: a cross-sectional study.

CMAJ Open 2022 Apr-Jun;10(2):E450-E459. Epub 2022 May 24.

Divisions of Urogynecology and Minimally Invasive Gynecologic Surgery (Lee, Kung, Gagnon, Liu), Department of Obstetrics and Gynecology, Sunnybrook Health Sciences Centre, University of Toronto; Division of Microbiology (Kozak), Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto; Sunnybrook Research Institute (Alavi, Mbareche, Perruzza, Jarvi, Salvant), Sunnybrook Health Sciences Centre, University of Toronto; Division of Maternal Fetal Medicine (Murphy), Department of Obstetrics and Gynecology, Sinai Health System; Temerty Faculty of Medicine (Perruzza, Jarvi); Division of Maternal Fetal Medicine (Ladhani), Department of Obstetrics and Gynecology; Divisions of Orthopaedic Surgery and Trauma Surgery (Yee, Jenkinson), Department of Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ont.

Background: The exposure risks to front-line health care workers caring for patients with SARS-CoV-2 infection undergoing surgery or obstetric delivery are unclear, and an understanding of sample types that may harbour virus is important for evaluating risk. We sought to determine whether SARS-CoV-2 viral RNA from patients with SARS-CoV-2 infection undergoing surgery or obstetric delivery was present in the peritoneal cavity of male and female patients, in the female reproductive tract, in the environment of the surgery or delivery suite (surgical instruments or equipment used, air or floors), and inside the masks of the attending health care workers.

Methods: We conducted a cross-sectional study from November 2020 to May 2021 at 2 tertiary academic Toronto hospitals, during urgent surgeries or obstetric deliveries for patients with SARS-CoV-2 infection. Read More

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Automated analysers underestimate atypical basophil count in myeloid neoplasms.

Int J Lab Hematol 2022 May 24. Epub 2022 May 24.

Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, USA.

Introduction: Recent data suggest basophils can adopt an atypical appearance in myeloid disorders including myeloproliferative neoplasms (MPNs) and myeloproliferative/myelodysplastic disease. We hypothesized that automated analysers may not accurately quantitate basophils in myeloid neoplasms based on scatter properties. This study examined basophil counts and properties in myeloid disorders by automated cell analyser, manual differential, and flow cytometry. Read More

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Feasibility of using different hydrothermal processes for sewage sludge management in China.

Sci Total Environ 2022 May 21:156154. Epub 2022 May 21.

Water Research Center, Shenzhen International Graduate School, Tsinghua University, Shenzhen, China; College of Engineering and Technology, American University of the Middle East, Kuwait.

Due to its tremendous volume and severe environmental concern, sewage sludge (SS) management and treatment are significant in China. The recent prohibition (June 2021) of reusing SS as organic fertilizers makes it urgent to develop alternative processes. However, there is currently little research analyzing the applicability of using HP for sewage SS treatment in China. Read More

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Early recognition of low-risk SARS-CoV-2 pneumonia: A model validated with initial data and IDSA/ATS minor criteria.

Chest 2022 May 21. Epub 2022 May 21.

Center for Biomedical Research Network in Respiratory Diseases (CIBERES). Madrid, Spain; University of Barcelona. Barcelona, Spain; Pneumology Department. Hospital Clinic of Barcelona. Barcelona, Spain; August Pi i Sunyer Biomedical Research Institute. Barcelona, Spain.

Background: A shortage of beds in the intensive care unit (ICU) and conventional ward during the COVID-19 pandemic led to a collapse of healthcare resources.

Research Question: Can admission data and minor criteria by the Infectious Diseases Society of America (IDSA) and American Thoracic Society (ATS) help identify patients with low-risk SARS-CoV-2 pneumonia?

Study Design And Methods: This multicenter cohort study included 1274 patients in a derivation cohort and 830 (first wave) and 754 (second wave) in two validation cohorts. A multinomial regression analysis was performed on the derivation cohort to compare the following patients: those admitted to the ward (assessed as low-risk); those admitted to the ICU directly; those transferred to the ICU after general ward admission; and those who died. Read More

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Associations between pericarotid fat density and image-based risk characteristics of carotid plaque.

Eur J Radiol 2022 May 20;153:110364. Epub 2022 May 20.

Nanjing Medical University, Nanjing, Jiangsu Province, PR China; Department of Radiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu Province, PR China; School of Medical Imaging, Xuzhou Medical University, Xuzhou, Jiangsu Province, PR China; Institute of Medical Imaging and Digital Medicine, Xuzhou Medical University, Xuzhou, Jiangsu Province, PR China. Electronic address:

Objectives: In this study, we aimed to evaluate the associations between pericarotid fat density (PFD) and various risk characteristics of carotid plaque.

Methods: We retrospectively evaluated consecutive patients who were subjected to both high-resolution MRI and carotid artery CT angiography CTA at our institution between January 2016 and April 2021. The section of the carotid artery with the most severe lumen stenosis was selected from each patient for analysis. Read More

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National Cancer Database trends in surgical resection of the breast primary for stage IV breast cancer.

Surg Oncol 2022 May 11;42:101778. Epub 2022 May 11.

Department of Surgery, UC San Diego, La Jolla, CA, USA; American College of Surgeons Cancer Research Program, USA. Electronic address:

Background: Survival benefit after resection of the breast primary for women with metastatic breast cancer reported in retrospective studies has not been uniformly confirmed by randomized controlled trials. To assess the need for dissemination of trial results by the ACS Cancer Research Program Dissemination and Implementation (ACS CRP D&I) committee, we analyzed trends and predictors of surgery and other therapies for stage IV breast cancer.

Methods: The National Cancer Database (NCDB) was queried to identify women diagnosed with clinical stage IV breast cancer of ductal, lobular, or metaplastic histology between 2004 and 2017. Read More

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Predicting 31- to 60-Day Heart Failure Rehospitalization Among Older Women.

Res Gerontol Nurs 2022 May 27:1-13. Epub 2022 May 27.

The current study sought to identify social, hemodynamic, and comorbid risk factors associated with 31-to 60-day heart failure (HF) rehospitalization in African American and Caucasian older (aged >65 years) women. A non-equivalent, case-control, quantitative design study using secondary data analysis of medical records from a local community hospital in the Southeast region of the United States was performed over a 3-year period. Relationships between predictor variables and the outcome variable, 31- to 60-day HF rehospitalization, were explored. Read More

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Vericiguat: A Novel Soluble Guanylate Cyclase Stimulator For Use in Patients with Heart Failure.

Cardiol Rev 2022 Jan 21. Epub 2022 Jan 21.

Division of Cardiology, Westchester Medical Center and New York Medical College, Valhalla, NY.

Heart failure affects 6.2 million Americans and is increasing annually in its frequency. Treatment of heart failure has been at the forefront of medical advancements due to the financial burden on our health care system. Read More

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January 2022

Prospective Comparative Effectiveness Trial of Multidisciplinary Lung Cancer Care Within a Community-Based Health Care System.

JCO Oncol Pract 2022 May 24:OP2100815. Epub 2022 May 24.

Multidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.

Purpose: Multidisciplinary lung cancer care is assumed to improve care delivery by increasing transparency, objectivity, and shared decision making; however, there is a lack of high-level evidence demonstrating its benefits, especially in community-based health care systems. We used implementation and team science principles to establish a colocated multidisciplinary lung cancer clinic in a large community-based health care system and evaluated patient experience and outcomes within and outside this clinic.

Methods: We conducted a prospective frequency-matched comparative effectiveness study (ClinicalTrials. Read More

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Efficacy and Cost of Maxillary Patient-Specific Implants in Orthognathic Surgery: A Review of Three Patient Cases.

Perm J 2022 Apr 5;26(1):137-142. Epub 2022 Apr 5.

Division of Maxillofacial Surgery, Kaiser Permanente Oakland Medical Center, Oakland, CA, USA.

Introduction: Patient-specific implants (PSIs) are accurate, efficient alternatives to traditional plate fixation. They are well-suited for use in procedures that require the utmost accuracy, stability, and efficiency. Although PSIs have demonstrated such qualities in craniomaxillofacial reconstruction, they have so far found limited utilization elsewhere. Read More

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Implications of video chat use for young children's learning and social-emotional development: Learning words, taking turns, and fostering familial relationships.

Wiley Interdiscip Rev Cogn Sci 2022 May 24:e1599. Epub 2022 May 24.

School of Communication Sciences and Disorders, McGill University, Montreal, Quebec, Canada.

Parents of young children use video chat differently than other screen media, paralleling expert recommendations (e.g., American Academy of Pediatrics Council on Communications and Media, 2016), which suggest that video chat, unlike other screen media, is acceptable for use by children under 18 months. Read More

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Higher education in nursing: Keys to success in online learning.

Nursing 2022 Jun;52(6):12-13

At American Public University System in Charles Town, W.Va., Elina Keiser is a professor in the RN-to-BSN and MSN programs, Stacey (Kram) Malinowski is the assistant dean and Chief Nursing Administrator, and Marcia Sotelo is the Department Chair of Nursing.

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ASHP National Survey of Pharmacy Practice in Hospital Settings: Clinical services and workforce-2021.

Am J Health Syst Pharm 2022 May 24. Epub 2022 May 24.

American Society of Health-System Pharmacists, Bethesda, MD, USA.

Disclaimer: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. Read More

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Reversing the Great Resignation in Nursing: More Things to Consider.

J Nurs Adm 2022 Jun;52(6):324-326

Author Affiliation: Chief Nursing Officer, The Advisory Board, Washington, DC.

Abstract: Much has been written about the impact of COVID-19 on the US labor market, most recently described as the Great Resignation of employees in American industries. The question for healthcare executives is whether factors prompting massive resignations in other industries have any bearing on efforts to retain the healthcare workforce, particularly in nursing, and what nursing leaders can do to address this trend. Read More

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Diversity, Equity, and Inclusion in the 2023 Magnet® Application Manual.

J Nurs Adm 2022 Jun;52(6):322-323

Author Affiliations: Senior Magnet Program Analyst, Magnet Recognition Program®, American Nurses Credentialing Center, Silver Spring, Maryland.

Abstract: The mission and vision of the Magnet Recognition Program® is to continually elevate patient care and transform healthcare globally through an environment where nurses and the interprofessional team flourish. Diversity, equity, and inclusion (DEI) affect healthcare workers and patients. The Commission on Magnet Recognition further integrated structures and processes involving DEI into the 2023 Magnet® Application Manual to emphasize the importance of organizations' enculturation of these initiatives as a part of the mission and vision. Read More

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A Survey of Musculoskeletal Disorders in the Orthopaedic Surgeon: Identifying Injuries, Exacerbating Workplace Factors, and Treatment Patterns in the Orthopaedic Community.

J Am Acad Orthop Surg Glob Res Rev 2022 May 1;6(5). Epub 2022 May 1.

From the Department of Orthopaedic Surgery (Dr. Swank, Dr. Furness, Dr. Rohde); the Department of Orthopaedic Research (Baker, Dr. Gehrke), Beaumont Health, Royal Oak, MI; and the Department of Orthopaedic Surgery (Baker, Dr. Rohde), Oakland University-William Beaumont School of Medicine, Rochester, MI.

Introduction: As demand for orthopaedic care increases, the orthopaedic community must preserve access to skilled physicians. Workplace hazards and related injuries or conditions contribute to musculoskeletal (MSK) stress on orthopaedic surgeons, which can lead to undesirable medical leaves of absence or early retirement. The purpose of this study was to identify and characterize work-related and non-work-related MSK conditions that affect orthopaedic surgeons and differential injury patterns among male and female surgeons. Read More

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Experimental Infection of Mink with SARS-COV-2 Omicron Variant and Subsequent Clinical Disease.

Emerg Infect Dis 2022 Jun;28(6):1286-1288

We report an experimental infection of American mink with SARS-CoV-2 Omicron variant and show that mink remain positive for viral RNA for days, experience clinical signs and histopathologic changes, and transmit the virus to uninfected recipients. Preparedness is crucial to avoid spread among mink and spillover to human populations. Read More

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Lam Qua and Peter Parker: Portraiture of Head and Neck Surgery in 19th-Century China.

Otolaryngol Head Neck Surg 2022 May 24:1945998221101186. Epub 2022 May 24.

Department of the History of Art, University of California, Riverside, California, USA.

In 1835, Peter Parker, an American surgeon and Presbyterian minister, established a hospital in Guangzhou and became the first Western head and neck surgeon in China. While Parker documented his most interesting cases in his journals, he also commissioned oil paintings of these patients from Lam Qua ([Formula: see text]), a prominent Chinese artist trained in British academic painting. Lam Qua produced 86 portraits of Dr Parker's patients, providing insight into not only the treatment of head and neck tumors but also the introduction of Western artistic techniques to 19th-century China. Read More

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Air Pollution, Socioeconomic Status, and Age-Specific Mortality Risk in the United States.

JAMA Netw Open 2022 May 2;5(5):e2213540. Epub 2022 May 2.

Harvard Center for Population and Development Studies, Cambridge, Massachusetts.

Importance: Prior studies on the association between fine particulate matter with diameters 2.5 μm or smaller (PM2.5) and probability of death have not applied multilevel analysis disaggregating data for US census tract, states, and counties, nor tested its interaction by socioeconomic status (SES). Read More

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Screening for Impaired Visual Acuity in Older Adults.

JAMA 2022 May 24. Epub 2022 May 24.

Department of Ophthalmology, School of Medicine, University of California, San Francisco.

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Lizards as Silent Hosts of Trypanosoma cruzi.

Emerg Infect Dis 2022 Jun;28(6):1250-1253

We assessed 4 lizard species in Chile for Trypanosoma cruzi, the causative agent of Chagas disease, and 1 species for its ability to transmit the protozoan to uninfected kissing bugs. All lizard species were infected, and the tested species was capable of transmitting the protozoan, highlighting their role as T. cruzi reservoirs. Read More

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Risk stratification in patients with anaplastic thyroid carcinoma: role of age.

Endocrine 2022 May 24. Epub 2022 May 24.

Department of Thyroid & Parathyroid Surgery, West China Hospital, Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, Sichuan, China.

Background: Thyroid carcinoma is the only cancer that regards age as an important predictor of thyroid cancer-specific survival (CSS). While the 8th American Joint Committee on Cancer (AJCC) staging system raised the age cutoff from 45 to 55 years for differentiated thyroid carcinoma (DTC) to more accurately predict the prognosis, there is no new information regarding the role of age in the prognosis of anaplastic thyroid carcinoma (ATC). The aim of this study was to determine the optimal age cutoff values for mortality risk stratification in ATC patients. Read More

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Well-to-wheel emissions and abatement strategies for passenger vehicles in two Latin American cities.

Environ Sci Pollut Res Int 2022 May 24. Epub 2022 May 24.

Departamento de Ingeniería Química y Ambiental, Facultad de Ingeniería, Universidad Nacional de Colombia, Bogotá, Colombia.

More stringent standards for engines and fuels are progressively implemented as alternatives to reduce on-road vehicle emissions. While electric vehicles appear as a perfect alternative since their engines do not emit pollutants, wear and dust resuspension (W&R) and indirect emissions associated with electricity production remain significant sources of pollution. This work compares well-to-wheel emissions (WTW) and abatement strategies for various types of passenger vehicles in Bogotá and Santiago for different pollutants (CO, PM, SO, and NOx) and greenhouse gases like CO equivalent (CO-Eq). Read More

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Impact of preoperative opioid use on patient-reported outcomes following primary total knee arthroplasty.

Eur J Orthop Surg Traumatol 2022 May 24. Epub 2022 May 24.

Department of Orthopedic Surgery, NYU Langone Health, 301 East 17 th Street , New York, NY, 10003, USA.

Purpose: The previous literature suggests that 25-30% of patients who undergo total knee arthroplasty (TKA) are using opioids prior to their surgery. This study aims to investigate the effect of preoperative opioid use on clinical outcomes and patient-reported outcome measures (PROMs) following TKA.

Methods: We retrospectively reviewed 329 patients who underwent primary TKA from 2019 to 2020, answered the preoperative opioid survey, and had available PROMs. Read More

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The effect of age and sex on esophageal hiatal surface area among normal North American adults using multidetector computed tomography.

Surg Radiol Anat 2022 May 24. Epub 2022 May 24.

Department of Biomedical Education and Data Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.

The size of the esophageal hiatus is clinically important for preserving the integrity of the lower esophageal sphincter mechanism. The purpose of this study was to systematically establish the mean hiatal surface area (HSA) for normal North American adults under physiologic conditions and assess the relationship between sex and age on HSA. Multi-Detector Computer Tomogram (MDCT) images of the esophageal hiatus in 119 healthy adult subjects (61 males and 58 females with an age range of 24-88 years) were retrospectively analyzed using the multi-planar reconstruction (MPR) technique to directly measure their hiatal length (long axis), width (short axis) and surface area at end inspiration. Read More

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1945-1964 WHO's Right to Health?

Linda M Richards

NTM 2022 May 24. Epub 2022 May 24.

Oregon State University, Corvallis, USA.

United States Atomic Energy Commission (USAEC) and UN agencies utilized techniques of power and negotiation to implement radiation exposure regulations. USAEC affiliated scientists' expertise was cultivated while establishing a radiation protection regime based on classified experiments. World Health Organization (WHO) leadership sought to manifest a human right to health, including a right to protection from radiation contamination. Read More

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Systematic evidence-based review: The application of noninvasive prenatal screening using cell-free DNA in general-risk pregnancies.

Genet Med 2022 May 10. Epub 2022 May 10.

American College of Medical Genetics and Genomics, Bethesda, MD.

Purpose: Noninvasive prenatal screening (NIPS) using cell-free DNA has been assimilated into prenatal care. Prior studies examined clinical validity and technical performance in high-risk populations. This systematic evidence review evaluates NIPS performance in a general-risk population. Read More

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Referral patterns to a pediatric orthopedic clinic: pediatric orthopedic surgeons are primary care musculoskeletal medicine physicians.

J Pediatr Orthop B 2022 May 24. Epub 2022 May 24.

WLH: Penn State Hershey Medical Center, Bone and Joint Institute, Hershey, Pennsylvania, USA.

In 2004, Reeder and in 2012, Schwend reported that inappropriate nonsurgical referrals to pediatric orthopedic clinics create a misuse of resources. Additional authors have called for re-emphasis and additional training in musculoskeletal medicine for primary care physicians (PCP) to improve the confidence, knowledge and performance when managing musculoskeletal conditions. The current study compares the diagnoses referred to a pediatric orthopedic clinic with diagnoses recommended for referral by the American Academy of Pediatrics (AAP) guidelines to determine if any improvement in the quality of referrals has occurred since Reeder and Schwend's article. Read More

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Comparing surgical strategies for end-stage anteromedial osteoarthritis : total versus unicompartmental knee arthroplasty.

Bone Jt Open 2022 May;3(5):441-447

Department of Orthopaedic Surgery, Clinical Orthopaedic Research Hvidovre, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark.

Aims: Treatment of end-stage anteromedial osteoarthritis (AMOA) of the knee is commonly approached using one of two surgical strategies: medial unicompartmental knee arthroplasty (UKA) or total knee arthroplasty (TKA). In this study we aim to investigate if there is any difference in outcome for patients undergoing UKA or TKA, when treated by high-volume surgeons, in high-volume centres, using two different clinical guidelines. The two strategies are 'UKA whenever possible' vs TKA for all patients with AMOA. Read More

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