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    2213 results match your criteria American Journal of Drug and Alcohol Abuse[Journal]

    1 OF 45

    Leveraging user perspectives for insight into cannabis concentrates.
    Am J Drug Alcohol Abuse 2018 Mar 7:1-14. Epub 2018 Mar 7.
    a Department of Psychiatry , Washington University School of Medicine , St. Louis , MO , USA.
    Background: The US has seen an increase in the popularity of highly concentrated forms of cannabis (hereafter concentrates) and too little is known about the potential risks associated with their use.

    Objectives: The present study aims to better understand the patterns and outcomes of concentrates use through the perspectives of young adult users.

    Methods: Participants (N = 234, 27. Read More

    Crowdsourcing as a method for collecting data pertaining to the effects of alcohol on perceptions of partner aggression.
    Am J Drug Alcohol Abuse 2018 Mar 7:1-8. Epub 2018 Mar 7.
    a Department of Biomedical Sciences , Rochester Institute of Technology , Rochester, NY, USA.
    Background: Efforts designed to investigate the effects of recent alcohol use on the perception of intimate partner aggression have been stultified by significant financial and logistical barriers that warrant the development of supplemental research methods that may result in more prolific investigation of the phenomenon.

    Objectives: The current study explored the viability of using online crowdsourcing to assess the effects of recent alcohol use on the perception of partner aggression.

    Method: Mechanical Turk was used to recruit a convenience sample of 60 males who were asked to provide information on their own use of partner aggression, their most recent episode of alcohol use, and their perception of the behaviors and characters depicted in a written partner aggression vignette. Read More

    Dynamic transitions between marijuana use and cigarette smoking among US adolescents and emerging adults.
    Am J Drug Alcohol Abuse 2018 Mar 7:1-11. Epub 2018 Mar 7.
    a Department of Epidemiology , University of Florida , Gainesville , FL , USA.
    Background: Marijuana and tobacco are considered two closely related substances. It is of great significance to understand the mutual impact of marijuana and cigarette use when more states in the US have legalized marijuana use.

    Objective: This study aims to investigate the transitions between marijuana and cigarette use among adolescents and emerging adults. Read More

    Using REDCap for ambulatory assessment: Implementation in a clinical trial for smoking cessation to augment in-person data collection.
    Am J Drug Alcohol Abuse 2018 Mar 7:1-16. Epub 2018 Mar 7.
    a Department of Psychiatry and Behavioral Sciences , Medical University of South Carolina , Charleston , SC , USA.
    Background: The use of ambulatory assessment to study behavior and physiology in daily life is becoming more common, yet barriers to implementation remain. Limitations in budget, time, and expertise may inhibit development or purchase of dedicated ambulatory assessment software. Research Electronic Data Capture (REDCap) is widely used worldwide, offering a cost-effective and accessible option for implementing research studies. Read More

    Gender differences in substance use treatment and substance use among adults on probation.
    Am J Drug Alcohol Abuse 2018 Feb 16:1-8. Epub 2018 Feb 16.
    c Criminology, Law and Society Program , George Mason University , Fairfax , VA , USA.
    Background: Although many formal and informal substance use treatment programs were originally designed for men, no studies have investigated how gender affects the use of substance use treatment modalities, and how gender differences in treatment utilization impact substance use in the unique probation context.

    Objective: To describe gender differences in use and effectiveness of substance use treatment modalities (formal and informal) among probationers.

    Methods: Longitudinal data were obtained from 335 individuals (93 women) who participated in the Motivational Assessment Program to Initiate Treatment (MAPIT) study. Read More

    Comparing methods of misclassification correction for studies of adolescent alcohol use.
    Am J Drug Alcohol Abuse 2018 ;44(2):160-166
    c Department of Behavioral Sciences and Health Education, Rollins School of Public Health , Emory University , Atlanta , GA , USA.
    Background: Despite concerns over measurement error, self-report continues to be the most common measure of adolescent alcohol use used by researchers. Objective measures of adolescent alcohol use continue to advance; however, they tend to be cost prohibitive for larger studies. By combining appropriate statistical techniques and validation subsamples, the benefits of objective alcohol measures can be made more accessible to a greater number of researchers. Read More

    The impact of PTSD clusters on cannabis use in a racially diverse trauma-exposed sample: An analysis from ecological momentary assessment.
    Am J Drug Alcohol Abuse 2018 Feb 14:1-11. Epub 2018 Feb 14.
    e Department of Psychiatry and Behavioral Science , University of North Dakota School of Medicine & Health Sciences , Fargo , ND , USA.
    Background: Accumulating evidence indicates a link between post-traumatic stress disorder (PTSD) and cannabis use and suggests that this link may vary as a function of the PTSD symptom cluster type. Consistent with negative reinforcement models of substance use, individuals with elevated Cluster D (Hyperarousal) symptoms may be more likely to use cannabis in response to elevated state anxiety and experience decreases in state anxiety after using cannabis.

    Objectives: We aimed to test hypotheses that the interaction of Cluster D and state anxiety would be related to subsequent cannabis use and that those with elevated Cluster D symptoms who used cannabis would report the greatest decreases in state anxiety. Read More

    Depressive symptoms in the trajectory of craving during smoking cessation treatment: A latent growth curve model.
    Am J Drug Alcohol Abuse 2018 Feb 8:1-8. Epub 2018 Feb 8.
    a Smoking and Addictive Disorders Unit, Faculty of Psychology, Department of Clinical Psychology and Psychobiology , University of Santiago de Compostela , Santiago de Compostela , Spain.
    Background: Depressive symptoms and craving are related to smoking maintenance; however, little is known about the association between trajectories of depressive symptoms and smoking craving after quitting.

    Objectives: We examined if depressive symptom change relates to change in craving following smoking cessation treatment.

    Methods: Participants were 362 (64. Read More

    Open-label pilot study of injectable naltrexone for cannabis dependence.
    Am J Drug Alcohol Abuse 2018 Feb 8:1-9. Epub 2018 Feb 8.
    a Division on Substance Abuse , New York State Psychiatric Institute , New York , NY , USA.
    Background: There are no FDA-approved pharmacotherapies for cannabis use disorders (CUD), despite the evaluation of numerous medications. Notably, chronic dosing of oral naltrexone decreases self-administration of cannabis in human laboratory studies.

    Objectives: To test the feasibility of long-acting injectable naltrexone for the treatment of CUD, while obtaining preliminary safety and efficacy data. Read More

    Exploring longitudinal course and treatment-baseline severity interactions in secondary outcomes of smoking cessation treatment in individuals with attention-deficit hyperactivity disorder.
    Am J Drug Alcohol Abuse 2018 Jan 25:1-7. Epub 2018 Jan 25.
    b Department of Psychiatry , University of Cincinnati , Cincinnati , OH, USA.
    Background: A double blind, placebo-controlled randomized trial (NCT00253747) evaluating osmotic-release oral system methylphenidate (OROS-MPH) for smoking-cessation revealed a significant interaction effect in which participants with higher baseline ADHD severity had better abstinence outcomes with OROS-MPH while participants with lower baseline ADHD severity had worse outcomes.

    Objectives: This current report examines secondary outcomes that might bear on the mechanism for this differential treatment effect.

    Methods: Longitudinal analyses were conducted to evaluate the effect of OROS-MPH on three secondary outcomes (ADHD symptom severity, nicotine craving, and withdrawal) in the total sample (N = 255, 56% Male), and in the high (N = 134) and low (N = 121) baseline ADHD severity groups. Read More

    Cigarette smoking and quit attempts among Latinos in substance use disorder treatment.
    Am J Drug Alcohol Abuse 2018 Jan 15:1-8. Epub 2018 Jan 15.
    b Philip R. Lee Institute for Health Policy Studies, University of California San Francisco , San Francisco , CA , USA.
    Background: Differences in tobacco use behaviors have been identified between Latinos and non-Latino whites in the general US population. Little is known about cigarette smoking and quitting behaviors of Latinos in treatment for substance use disorders (SUDs), who represent two major tobacco-vulnerable groups.

    Objectives: To compare, in a national sample of persons enrolled in SUD treatment, demographic, drug use, and smoking and quitting prevalence and behaviors between Latinos and non-Latino whites. Read More

    Pharmacogenetic analysis of opioid dependence treatment dose and dropout rate.
    Am J Drug Alcohol Abuse 2018 Jan 15:1-10. Epub 2018 Jan 15.
    a Center for Neurobiology and Behavior, Department of Psychiatry , University of Pennsylvania School of Medicine , Philadelphia , PA , USA.
    Background: Currently, no pharmacogenetic tests for selecting an opioid-dependence pharmacotherapy have been approved by the US Food and Drug Administration.

    Objectives: Determine the effects of variants in 11 genes on dropout rate and dose in patients receiving methadone or buprenorphine/naloxone ( Identifier: NCT00315341). Read More

    Drug use patterns and predictors among homeless youth: results of an ecological momentary assessment.
    Am J Drug Alcohol Abuse 2017 Dec 29:1-10. Epub 2017 Dec 29.
    e The University of Oklahoma Health Sciences Center, Oklahoma Tobacco Research Center , Oklahoma City , OK , USA.
    Background: Alcohol and drug use is associated with significant morbidity and mortality and is highly prevalent among homeless youth. Ecological Momentary Assessments (EMA) have been used to examine the effect of urges on drug use, though not among homeless youth.

    Objectives: We assessed the patterns of drug use and the correlation between real-time contextual factors and drug use using EMA collected daily. Read More

    Patterns of simultaneous and concurrent alcohol and marijuana use among adolescents.
    Am J Drug Alcohol Abuse 2017 Dec 20:1-11. Epub 2017 Dec 20.
    a Institute for Social Research , University of Michigan , Ann Arbor , MI , USA.
    Background: Alcohol and marijuana are the most commonly used substances among adolescents but little is known about patterns of co-use.

    Objectives: This study examined patterns of concurrent (not overlapping) and simultaneous (overlapping) use of alcohol and marijuana among adolescents.

    Methods: Data from US-national samples of 12th graders (N = 84,805, 48. Read More

    Benefit requirements for substance use disorder treatment in state health insurance exchanges.
    Am J Drug Alcohol Abuse 2017 Dec 20:1-5. Epub 2017 Dec 20.
    b Department of Psychiatry , School of Medicine, Stanford University, Stanford, CA, USA.
    Background: Established in 2014, state health insurance exchanges have greatly expanded substance use disorder (SUD) treatment coverage in the United States as qualified health plans (QHPs) within the exchanges are required to conform to parity provisions laid out by the Affordable Care Act and the Mental Health Parity and Addiction Equity Act (MHPAEA). Coverage improvements, however, have not been even as states have wide discretion over how they meet these regulations.

    Objective: How states regulate SUD treatment benefits offered by QHPs has implications for the accessibility and quality of care. Read More

    The impact of stepfamily relationship quality on emerging adult non-medical use of prescription drugs.
    Am J Drug Alcohol Abuse 2017 Dec 20:1-9. Epub 2017 Dec 20.
    a Brigham Young University, School of Social Work , Provo , UT , USA.
    Background: Emerging adults aged 18 to 25 are most at-risk for non-medical use of prescription drugs (NMUPD). While the literature dedicated to emerging-adult NMUPD has explored risk and protective factors at an individual level, much less is known regarding how interpersonal and familial factors relate to NMUPD. Because interpersonal bonds can have a significant impact on behavior, familial factors may be important predictors of NMUPD among emerging adults. Read More

    Mediating effect of deviant peers on the relationship between sensation seeking and lifetime smoking among high school students.
    Am J Drug Alcohol Abuse 2018 1;44(3):358-367. Epub 2017 Dec 1.
    b Department of Nursing, Graduate School , Kyung Hee University , Seoul , Republic of Korea.
    Background: Despite the greater risk of lifetime smoking among high sensation seekers, it is difficult to change a sensation seeking tendency through interventions. Therefore, it is important to identify a modifiable factor mediating the link between these two conditions in order to weaken or disconnect the association.

    Objectives: Based on the literature, deviant peers may play a pivotal role in explaining this association. Read More

    Medication-assisted treatment for youth with opioid use disorder: Current dilemmas and remaining questions.
    Am J Drug Alcohol Abuse 2018 30;44(2):143-146. Epub 2017 Nov 30.
    a British Columbia Centre on Substance Use, British Columbia Centre for Excellence in HIV/AIDS , St. Paul's Hospital , Vancouver , BC , Canada.
    The prevalence of risky opioid use, opioid use disorder, and related harms continue to rise among youth (adolescents and young adults age 15-25) in North America. With an increasing number of opioid overdoses, there remain significant barriers to care for youth with opioid use disorder, and there is an urgent need to expand evidence-based care for treatment of opioid use disorder among this population. Based on the extensive literature on treatment of opioid use disorder among adults, medicated-assisted treatment is likely to be an important or even essential component of treatment of opioid use disorder for most youth. Read More

    High inpatient utilization among Veterans Health Administration patients with substance-use disorders and co-occurring mental health conditions.
    Am J Drug Alcohol Abuse 2018 2;44(3):386-394. Epub 2017 Nov 2.
    b Health Services Research & Development (HSR&D) Seattle Center of Innovation for Veteran Centered and Value-Driven Care , VA Puget Sound Health Care System , Seattle , WA , USA.
    Background: Substance-use disorders (SUDs) are common and costly conditions. Understanding high inpatient utilization (HIU) among patients with SUD can inform the development of treatment approaches designed to reduce healthcare expenditures and improve service quality.

    Objectives: To examine the prevalence, type, and predictors of HIU among patients with SUD and co-occurring mental health conditions. Read More

    Molecular spectroscopic studies examining the interactions between phenobarbital and human serum albumin in alcohol consumption.
    Am J Drug Alcohol Abuse 2018 2;44(3):321-328. Epub 2017 Nov 2.
    b Institute of Bioorganic & Medicinal Chemistry, School of Chemistry and Chemical Engineering , Southwest University , Chongqing , P.R. China.
    Background: Alcohol dependence is associated with a wide range of serious mental, physical, and social consequences and is one of the most common chronic diseases worldwide. Barbiturates, which are a first-line treatment in the clinic for alcohol withdrawal, may result in combined barbiturate and alcohol use. Their co-use abuse may promote synergistic effects between barbiturates and alcohol in vivo. Read More

    Assessment of the validity of the CUDIT-R in a subpopulation of cannabis users.
    Am J Drug Alcohol Abuse 2018 23;44(1):19-23. Epub 2017 Oct 23.
    d Department of Psychiatry , University of Pennsylvania, Perelman School of Medicine , Philadelphia , PA , USA.
    Background: The Cannabis Use Disorders Identification Test-Revised (CUDIT-R) is an 8-item measure used to screen for cannabis use disorders (CUD). Despite widespread use of the tool, assessments of the CUDIT-R's validity in subpopulations are limited.

    Objectives: The current study tested the structural validity and internal consistency of one of the most widely used screening measures for CUD (i. Read More

    Substance use among bi/multiracial youth in the United States: Profiles of psychosocial risk and protection.
    Am J Drug Alcohol Abuse 2018 20;44(2):206-214. Epub 2017 Oct 20.
    c School of Social Work , College for Public Health and Social Justice, Saint Louis University , St. Louis , MO , USA.
    Background: Bi/multiracial youth face higher risk of engaging in substance use than most monoracial youth.

    Objectives: This study contrasts the prevalence of substance use among bi/multiracial youth with that of youth from other racial/ethnic groups, and identifies distinct profiles of bi/multiracial youth by examining their substance use risk.

    Methods: Using data from the National Survey on Drug Use and Health (collected between 2002 and 2014), we analyze data for 9,339 bi/multiracial youth ages 12-17 living in the United States. Read More

    Strengthening the working alliance through a clinician's familiarity with the 12-step approach.
    Am J Drug Alcohol Abuse 2018 19;44(3):378-385. Epub 2017 Oct 19.
    c School of Social Welfare, University at Albany, State University of New York , Albany , NY , USA.
    Background: The working alliance plays an important role in the substance use disorder treatment process. Many substance use disorder treatment providers incorporate the 12-Step approach to recovery into treatment. With the 12-Step approach known among many clients and clinicians, it may well factor into the therapeutic relationship. Read More

    Increasing availability of illicit and prescription opioids among people who inject drugs in a Canadian setting, 2010-2014.
    Am J Drug Alcohol Abuse 2018 19;44(3):368-377. Epub 2017 Oct 19.
    b British Columbia Centre on Substance Use , British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital , Vancouver , Canada.
    Background: Nonmedical use of prescription opioid and illicit opioid has been increasing at an alarming rate in North America over the past decade.

    Objective: We sought to examine the temporal trends and correlates of the availability of illicit and prescription opioids among people who inject drugs (PWID) in Vancouver, Canada.

    Methods: Data were derived from three prospective cohort studies of PWID in Vancouver between 2010 and 2014. Read More

    Evaluation of the appropriate use of a CIWA-Ar alcohol withdrawal protocol in the general hospital setting.
    Am J Drug Alcohol Abuse 2017 Oct 5:1-8. Epub 2017 Oct 5.
    c Department of Psychiatry , Stony Brook University, School of Medicine, Stony Brook , NY , USA.
    Background: The Clinical Institute Withdrawal Assessment-Alcohol, Revised (CIWA-Ar) is an assessment tool used to quantify alcohol withdrawal syndrome (AWS) severity and inform benzodiazepine treatment for alcohol withdrawal.

    Objectives: To evaluate the prescribing patterns and appropriate use of the CIWA-Ar protocol in a general hospital setting, as determined by the presence or absence of documented AWS risk factors, patients' ability to communicate, and provider awareness of the CIWA-Ar order.

    Methods: This retrospective chart review included 118 encounters of hospitalized patients placed on a CIWA-Ar protocol during one year. Read More

    The mixed message behind "Medication-Assisted Treatment" for substance use disorder.
    Am J Drug Alcohol Abuse 2018 18;44(2):147-150. Epub 2017 Sep 18.
    b UT Southwestern Medical Center , Department of Psychiatry , Dallas , TX , USA.
    The gap between treatment utilization and treatment need for substance use disorders (SUDs) remains a significant concern in our field. While the growing call to bridge this gap often takes the form of more treatment services and/or better integration of existing services, this perspective proposes that more effective labels for and transparent descriptions of existing services would also have a meaningful impact. Adopting the perspective of a consumer-based health-care model (wherein treatments and services are products and patients are consumers) allows us to consider how labels like Addiction-focused Medical Management, Medication-Assisted Treatment, Medication-Assisted Therapy, and others may actually be contributing to the underutilization problem rather than alleviating it. Read More

    Associated factors of readiness to change in young adult risky drinkers.
    Am J Drug Alcohol Abuse 2018 22;44(3):348-357. Epub 2017 Aug 22.
    a Health Behavior Research and Training Institute at the School of Social Work , University of Texas , Austin , TX , USA.
    Background: Readiness to change alcohol use has been associated with a number of predictors including emotional distress, drinking severity, and consequence severity, as well as with static demographic factors such as gender and race/ethnicity.

    Objective: To examine the relationships among these variables and readiness to change alcohol use in young adults.

    Methods: Structural equation modeling was used to test pathways of readiness to change in 1,256 young adult patients (78% male/22% female) ages 18-29 who were provided screening, brief intervention and referral to treatment (SBIRT) as part of a Substance Abuse and Mental Health Services Administration (SAMHSA) Treatment Capacity Expansion Project. Read More

    Transitioning from methadone to buprenorphine maintenance in management of opioid use disorder during pregnancy.
    Am J Drug Alcohol Abuse 2018 22;44(3):310-316. Epub 2017 Aug 22.
    a Department of Psychiatry , Vanderbilt University Medical Center , Nashville , TN , USA.
    Background: Opioid use disorder during pregnancy is a growing health concern. Methadone maintenance is the treatment of choice but emerging data indicate buprenorphine is a viable alternative. Due to costs and limited accessibility of methadone, pregnant women may require transition from methadone to buprenorphine for maintenance treatment. Read More

    Neuropsychological comparisons of cocaine versus methamphetamine users: A research synthesis and meta-analysis.
    Am J Drug Alcohol Abuse 2018 21;44(3):277-293. Epub 2017 Aug 21.
    c Department of Psychiatry , University of California San Diego , La Jolla , CA , USA.
    Background: Previous meta-analytical research examining cocaine and methamphetamine separately suggests potentially different neuropsychological profiles associated with each drug. In addition, neuroimaging studies point to distinct structural changes that might underlie differences in neuropsychological functioning.

    Objectives: This meta-analysis compared the effect sizes identified in cocaine versus methamphetamine studies across 15 neuropsychological domains. Read More

    Repetitive transcranial magnetic stimulation (rTMS) administration to heavy cannabis users.
    Am J Drug Alcohol Abuse 2018 14;44(1):47-55. Epub 2017 Aug 14.
    a Department of Psychiatry , Medical University of South Carolina , Charleston , SC , USA.
    Background: Cannabis use disorder (CUD) is a common condition with few treatments. Several studies in other substance use disorders have found that applying repetitive transcranial magnetic stimulation (rTMS) to the dorsolateral prefrontal cortex (DLPFC) decreases cue-elicited craving and possibly decreases use. To date, there have been no studies attempting to use rTMS in CUD. Read More

    Effects of alcohol consumption on blood pressure in hypertensive women.
    Am J Drug Alcohol Abuse 2018 14;44(2):200-205. Epub 2017 Aug 14.
    b Department of Psychiatry , Harvard Medical School , Boston , MA , USA.
    Background: Problem drinking carries significant health burdens, including an increased risk of hypertension. The effect of chronic alcohol intake on blood pressure (BP) in women is understudied and poorly understood.

    Objectives: We sought to examine the relationships between drinking habits and BP in hypertensive women. Read More

    Homeless women's service use, barriers, and motivation for participating in substance use treatment.
    Am J Drug Alcohol Abuse 2018 14;44(2):252-262. Epub 2017 Aug 14.
    b Department of Quantitative Methods , University of Massachusetts Medical School , Worcester , MA , USA.
    Background: Homeless women are at high risk for substance use disorder (SUD), and are a growing proportion of the homeless population. However, homeless women experience barriers to engaging in substance use services.

    Objectives: Among homeless women with SUD, to explore service use, motivation to change, service barriers, and willingness to have substance use and mental health problems addressed in primary health care. Read More

    A novel non-opioid protocol for medically supervised opioid withdrawal and transition to antagonist treatment.
    Am J Drug Alcohol Abuse 2018 10;44(3):302-309. Epub 2017 Aug 10.
    b Addiction Recovery Service, Swedish Medical Center , Seattle , WA , USA.
    Background: The clinical feasibility of a novel non-opioid and benzodiazepine-free protocol was assessed for the treatment of medically supervised opioid withdrawal and transition to subsequent relapse prevention strategies.

    Methods: A retrospective chart review of DSM-IV diagnosed opioid-dependent patients admitted for inpatient medically supervised withdrawal examined 84 subjects (52 males, 32 females) treated with a 4-day protocol of scheduled tizanidine, hydroxyzine, and gabapentin. Subjects also received ancillary medications as needed, and routine counseling. Read More

    Recovery high schools: Effect of schools supporting recovery from substance use disorders.
    Am J Drug Alcohol Abuse 2018 2;44(2):175-184. Epub 2017 Aug 2.
    b School of Medicine and Public Health, Department of Population Health Sciences , University of Wisconsin-Madison , Madison , WI , USA.
    Background: Recovery high schools (RHSs) provide post-treatment education and recovery support for young people with substance use disorders (SUDs). This is the first quasi-experimental outcome study to determine RHS effectiveness relative to students in non-RHSs.

    Objectives: To examine effects of RHS attendance on academic and substance use outcomes among adolescents treated for SUDs 6 months after recruitment to the study. Read More

    Effects of propofol on conditioned place preference in male rats: Involvement of nitrergic system.
    Am J Drug Alcohol Abuse 2018 27;44(2):167-174. Epub 2017 Jul 27.
    b Neuropsychopharmacology Application and Research Center (NPARC) , Üsküdar University , Istanbul , Turkey.
    Background: Drug-induced conditioned place preference (CPP) is linked to the addictive properties of the drug used. The number of studies that have investigated the effects of propofol on CPP is limited. Research findings suggest that nitric oxide (NO) might play an important role in substance use disorders. Read More

    Transgenerational modification of hippocampus TNF-α and S100B levels in the offspring of rats chronically exposed to morphine during adolescence.
    Am J Drug Alcohol Abuse 2018 27;44(1):95-102. Epub 2017 Jul 27.
    b Department of Physiology, Faculty of Medicine , Arak University of Medical Sciences , Arak , Iran.
    Background: TNF-α and S100B are important signaling factors that are involved in many aberrant conditions of the brain. Chronic morphine exposure causes aberrant modifications in the brain.

    Objectives: We examined the consequences of chronic morphine consumption by parents before mating on hippocampus TNF-α and S100B levels in the parents and their offspring. Read More

    Adult attachment and drinking context as predictors of alcohol problems and relationship satisfaction in college students.
    Am J Drug Alcohol Abuse 2018 25;44(3):339-347. Epub 2017 Jul 25.
    b Department of Counseling and Psychology in Education , University of South Dakota , Vermillion , South Dakota , USA.
    Background: Evidence suggests that for young adults, intimate partners influence each other's drinking patterns. Therefore, exploration of variables related to intimate partner relationships (such as attachment style) could broaden the current understanding of risk factors for alcohol problems in this demographic.

    Objectives: The current study examined the role of drinking context in the relationships among insecure attachment, alcohol problems, and relationship satisfaction. Read More

    Working memory capacity and addiction treatment outcomes in adolescents.
    Am J Drug Alcohol Abuse 2018 20;44(2):185-192. Epub 2017 Jul 20.
    b Department of Child & Adolescent Psychiatry , Oregon Health & Science University , Portland , OR , USA.
    Background: Brief addiction treatments including motivational interviewing (MI) have shown promise with adolescents, but the factors that influence treatment efficacy in this population remain unknown. One candidate is working memory, the ability to hold a fact or thought in mind. This is relevant, as in therapy, a client must maintain and manipulate ideas while working with a clinician. Read More

    Rural and urban substance use differences: Effects of the transition to college.
    Am J Drug Alcohol Abuse 2018 20;44(2):224-234. Epub 2017 Jul 20.
    d Department of Psychological Sciences , Purdue University , West Lafayette , IN , USA.
    Background: With approximately 20% of Americans residing in rural communities, substance use differences is an important topic for appropriate use of resources, policy decisions, and the development of prevention and intervention programs.

    Objectives: The current study examined differences in alcohol, tobacco, and marijuana use among students from rural and urban backgrounds across the transition to college.

    Methods: Participants were 431 (48% male) undergraduate students from a large, public southeastern university who provided yearly alcohol, tobacco, and marijuana use data during freshman, sophomore, and junior years. Read More

    Increased blood 8-hydroxy-2-deoxyguanosine levels in methamphetamine users during early abstinence.
    Am J Drug Alcohol Abuse 2018 20;44(3):395-402. Epub 2017 Jul 20.
    b Department of Psychiatry , School of Medicine, College of Medicine, Taipei Medical University , Taipei , Taiwan.
    Background: Reactive oxygen species (ROS) are thought to play a role in the adverse physical and mental consequences of methamphetamine usage. The oxidative DNA adduct 8-hydroxy-2'-deoxyguanosine (8-OHdG) is a well-known biomarker of ROS-induced DNA damage. Currently, there is insufficient clinical information about methamphetamine-induced oxidative DNA damage. Read More

    Effects of depression and past-year binge drinking on cognitive control processes during a flanker task in college-aged adults.
    Am J Drug Alcohol Abuse 2018 20;44(2):263-272. Epub 2017 Jul 20.
    a Case Western Reserve University , Department of Psychological Sciences , Cleveland , OH , USA.
    Background: Recent but largely separate literatures have examined neurocognitive alterations related to both depression and binge drinking, suggesting similar patterns of impairments in attention control and decisional processes. However, depression and problematic alcohol use tend to co-occur, and few studies have examined whether cognitive processing effects of depression and binge drinking are independent or interacting.

    Objective: The current study examined joint effects of depressive symptoms and past-year binge drinking on cognitive processing (measured via EEG assessment). Read More

    Surveying the opinions of Pennsylvania Chiefs of Police toward officers carrying and administering naloxone.
    Am J Drug Alcohol Abuse 2018 30;44(2):244-251. Epub 2017 Jun 30.
    a Penn State Milton S. Hershey Medical Center , Department of Emergency Medicine, Division of Prehospital and Transport Medicine , Hershey PA , USA.
    Background: Recent legislation in Pennsylvania allows police officers to administer naloxone to individuals in an opioid overdose. Pressure has subsequently been placed on police departments to adopt naloxone programs.

    Objective: To survey Pennsylvania Chiefs of Police regarding potential obstacles to officer-administered naloxone, and their overall opinion toward such programs. Read More

    Interaction between the ADH1B*3 allele and drinking motives on alcohol use among Black college students.
    Am J Drug Alcohol Abuse 2018 29;44(3):329-338. Epub 2017 Jun 29.
    a Department of Psychology , Syracuse University , Syracuse , NY , USA.
    Background: Black young adults have lower rates of alcohol use than other racial groups. Genetic factors may protect against drinking. Specifically, the ADH1B*3 allele is present almost exclusively in Black populations and has been protective against alcohol use and alcohol use disorder. Read More

    Longitudinal associations between outpatient medical care use and substance use among rural stimulant users.
    Am J Drug Alcohol Abuse 2018 29;44(2):235-243. Epub 2017 Jun 29.
    a Department of Psychiatry , University of Arkansas for Medical Sciences , Little Rock , AR , USA.
    Background: Negative views toward substance use treatment among some rural substance users and limited treatment resources in rural areas likely affect substance use utilization. It is therefore important to determine whether accessing healthcare options other than substance use treatment, specifically outpatient medical care (OMC), is associated with reductions in substance use.

    Objectives: We examined whether use of OMC was associated with reductions in substance use among rural substance users over a three-year period. Read More

    Effect of chronic γ-hydroxybutyrate (GHB) administration on GHB toxicokinetics and GHB-induced respiratory depression.
    Am J Drug Alcohol Abuse 2017 Nov 29;43(6):686-693. Epub 2017 Jun 29.
    a Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences , University at Buffalo, State University of New York , Buffalo , NY , USA.
    Background: γ-hydroxybutyrate (GHB) has a high potential for illicit use; overdose of this compound results in sedation, respiratory depression and death. Tolerance to the hypnotic/sedative and electroencephalogram effects of GHB occurs with chronic GHB administration; however, tolerance to respiratory depression has not been evaluated. GHB toxicodynamic effects are mediated predominantly by GABAreceptors. Read More

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