- María C Ovejero-Benito,
- Ester Muñoz-Aceituno,
- Alejandra Reolid,
- Miriam Saiz-Rodríguez,
- Francisco Abad-Santos,
- Esteban Daudén
Am J Clin Dermatol 2017 Sep 18. Epub 2017 Sep 18.
Dermatology Department, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria la Princesa (IIS-IP), Madrid, Spain.
Pharmacogenetics is the study of variations in DNA sequence related to drug response. Moreover, the evolution of biotechnology and the sequencing of human DNA have allowed the creation of pharmacogenomics, a branch of genetics that analyzes human genes, the RNAs and proteins encoded by them, and the inter-and intra-individual variations in expression and function in relation to drug response. Pharmacogenetics and pharmacogenomics are being used to search for biomarkers that can predict response to systemic treatments, including those for moderate-to-severe psoriasis. Read More