1,569 results match your criteria American Journal On Addictions[Journal]


Worries About Discontinuing Buprenorphine Treatment: Scale Development and Clinical Correlates.

Am J Addict 2019 Apr 16. Epub 2019 Apr 16.

Department of Behavioral Medicine and Addictions Resaerch, Butler Hospital, Providence, Rhode Island.

Background And Objectives: Despite the benefits of maintenance buprenorphine treatment for opioid use disorder (OUD), many individuals report an interest in discontinuing the medication, while also expressing worries about tapering. The purpose of this study was to develop a measure of worries about buprenorphine discontinuation ("Off Bupe") and determine the demographic and clinical characteristics associated with these worries.

Methods: Between May 2017 and May 2018, we surveyed adults in an outpatient primary care buprenorphine program (n = 138). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12884DOI Listing

Evaluation of an Online Residency Training in Tobacco Use Disorder.

Am J Addict 2019 Apr 16. Epub 2019 Apr 16.

Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey.

Background And Objectives: Despite the overwhelming need for tobacco use disorder (TUD) treatment in behavioral health settings, few models have emerged for training psychiatry residents. One barrier may be a lack of curricula or faculty expertize in this area. The goal of this project was to develop and evaluate a 3 hour online webinar-based course for teaching psychiatry residents about TUD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12885DOI Listing

Initiation Sequence of E-Cigarette and Cigarette Smoking among US Adolescents: A National Study.

Am J Addict 2019 Apr 16. Epub 2019 Apr 16.

Center for the Study of Drugs, Alcohol, Smoking, and Health, Department of Health Behavior and Biological Sciences, School of Nursing, University of Michigan, Ann Arbor, Michigan.

Background And Objectives: The primary objectives were to: (1) examine the initiation sequence of e-cigarette use and cigarette smoking; (2) assess other substance use as a function of the initiation sequence of e-cigarettes and cigarettes; and (3) investigate the role of early e-cigarette initiation among US secondary school students.

Methods: Data were collected via self-administered questionnaires from independent 2015 and 2016 nationally representative cross-sectional samples of 8th grade, 10th grade, and 12th grade students (N = 36 410).

Results: The lifetime initiation sequence included: (1) e-cigarette use before cigarette smoking (1. Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1111/ajad.12886
Publisher Site
http://dx.doi.org/10.1111/ajad.12886DOI Listing
April 2019
1 Read

Rapid micro-induction of buprenorphine/naloxone for opioid use disorder in an inpatient setting: A case series.

Am J Addict 2019 Mar 22. Epub 2019 Mar 22.

Foundry Central Office, Vancouver, Canadian Province, Canada.

Background And Objectives: Buprenorphine/naloxone has been shown to be effective in the treatment of opioid use disorder. Due to its pharmacological properties, induction can be challenging, time-consuming, and result in sudden onset of withdrawal symptoms.

Methods: Retrospective case series (n = 2). Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1111/ajad.12869
Publisher Site
http://dx.doi.org/10.1111/ajad.12869DOI Listing
March 2019
5 Reads

Brief report: Characterization of marijuana use in us college students by state marijuana legalization status as reported to an online survey.

Am J Addict 2019 Mar 22. Epub 2019 Mar 22.

Department of Emergency Medicine, Denver Health Hospital, Denver, Colorado.

Background And Objective: US college student marijuana use is the highest since 1980. The objective was to investigate use characteristics among college students.

Methods: The RADARS® System College Survey Program surveyed individuals in a university, technical or online school. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12870DOI Listing

Issue Information - Editorial Board.

Authors:

Am J Addict 2019 Feb;28(2):47-48

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12872DOI Listing
February 2019

Issue Information - ToC.

Authors:

Am J Addict 2019 Feb;28(2):49-50

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12873DOI Listing
February 2019

Cannabis legislation and substance use disorder treatment.

Am J Addict 2019 Feb;28(2):127-129

McLean Hospital, Harvard Medical School, Belmont, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12863DOI Listing
February 2019

The potency of social versus drug rewards.

Authors:

Am J Addict 2019 Feb 25;28(2):130-131. Epub 2019 Feb 25.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12864DOI Listing
February 2019

The CASTRO study: Unsafe sexual behaviors and illicit drug use among gay and bisexual men who use anabolic steroids.

Am J Addict 2019 Feb 6;28(2):101-110. Epub 2019 Feb 6.

Biological Psychiatry Laboratory, McLean Hospital, Belmont, Massachusetts.

Background And Objectives: The majority of anabolic androgenic steroid (AAS) studies have focused on the general male population. Approximately 15% of gay or bisexual men are seropositive for HIV and many AASs are administered via injection. Thus, AAS use among gay and bisexual men likely poses a greater risk of spreading infectious disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12865DOI Listing
February 2019
1 Read

Prescription opioid misuse and comorbid substance use: Past 30-day prevalence, correlates and co-occurring behavioral indicators in the 2016 National Survey on Drug Use and Health.

Am J Addict 2019 Feb 31;28(2):111-118. Epub 2019 Jan 31.

Department of Kinesiology, Health, & Nutrition, University of Texas at San Antonio, San Antonio, Texas.

Background And Objectives: Prescription opioid misuse has not been well examined in the context of comorbid substance use in representative samples of substance users. Past 30-day comorbid prescription opioid misuse and recreational substance use (eg, alcohol, marijuana, cocaine, etc.) was studied in a representative sample of substance users in the United States using the 2016 National Survey on Drug Use and Health (NSDUH). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12866DOI Listing
February 2019

Preclinical efficacy of an anti-methamphetamine vaccine using E6020 adjuvant.

Am J Addict 2019 Feb 31;28(2):119-126. Epub 2019 Jan 31.

Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas.

Background And Objective: Methamphetamine (MA) substance use disorder (SUD) does not have an efficacious pharmacotherapy. We developed a MA vaccine and investigated its potential to attenuate MA induced responses.

Methods: We examined a novel adjuvant, E6020, a Toll-like receptor-4 (TLR-4) agonist combined with tetanus-toxoid conjugated to succinyl-methamphetamine (TT-SMA) adsorbed on aluminum hydroxide (alum). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12867DOI Listing
February 2019
2 Reads

Review article: Effective management of opioid withdrawal symptoms: A gateway to opioid dependence treatment.

Am J Addict 2019 Feb 31;28(2):55-62. Epub 2019 Jan 31.

Professional Assistance Program of New Jersey, Inc., Princeton, New Jersey.

Background And Objectives: The opioid crisis has taken an immense toll in the United States. On average, five lives are lost to an opioid overdose every hour of the day; estimated costs associated with opioid misuse exceed $500 billion annually. Illicit opioid discontinuation is the first step in the treatment of opioid use disorder (OUD), and transition to an opioid agonist may initiate treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12862DOI Listing
February 2019
3 Reads

No increased pain among opioid-dependent individuals treated with extended-release naltrexone or buprenorphine-naloxone: A 3-month randomized study and 9-month open-treatment follow-up study.

Am J Addict 2019 Feb 31;28(2):77-85. Epub 2019 Jan 31.

Department of R&D in Mental Health, Akershus University Hospital, Lørenskog, Norway.

Background And Objectives: It is presently unclear whether extended-release naltrexone hydrochloride treatment induces pain or aggravates existing pain among individuals with opioid use disorders. We assessed changes in pain among individuals receiving treatment with either extended-release naltrexone hydrochloride or buprenorphine-naloxone hydrochloride.

Methods: This randomized prospective open-label clinical study included 143 participants (aged 18-60 years) with opioid dependencies, recruited from outpatient addiction clinics at five urban hospitals in Norway. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ajad.12859
Publisher Site
http://dx.doi.org/10.1111/ajad.12859DOI Listing
February 2019
2 Reads

Impulsiveness as a predictor of topiramate response for cocaine use disorder.

Am J Addict 2019 Feb 21;28(2):71-76. Epub 2019 Jan 21.

Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia.

Background/objectives: Topiramate has been studied in the treatment of substance use disorders and is often used off-label in the treatment of other disorders with impaired impulse control. We sought to determine whether impulsiveness could predict topiramate treatment response in individuals with cocaine use disorder (CUD).

Methods: In a post-hoc analysis of a 12-week, double-blind, randomized, placebo-controlled trial of topiramate for CUD, we examined the relationship between response to treatment and participants' baseline score on the Barrett Impulsiveness Scale (BIS-11). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12858DOI Listing
February 2019
3 Reads

Buprenorphine for the treatment of posttraumatic stress disorder.

Am J Addict 2019 Feb 21;28(2):86-91. Epub 2019 Jan 21.

Center for Innovations in Quality, Effectiveness, and Safety, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas.

Background And Objectives: The core pharmacological treatment of Post-Traumatic Stress Disorder (PTSD) is selective serotonin reuptake inhibitors (SSRIs), although remission is only around 30% with them. Many patients will self-treat with opioids and due to the opiate system involvement in dysphoric mood and anxiety/stress responses, it is likely that antagonism of the kappa opioid receptor (KOR) system represents a potential target for treatment of PTSD. The aim of this study is to compare response of PTSD symptoms when antagonizing KOR via buprenorphine/naloxone compared to SSRIs or opioid therapy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12860DOI Listing
February 2019
36 Reads

Comparison of opioid use disorder among male veterans and non-veterans: Disorder rates, socio-demographics, co-morbidities, and quality of life.

Am J Addict 2019 Feb 21;28(2):92-100. Epub 2019 Jan 21.

Department of Psychiatry, School of Medicine, Yale University, New Haven, Connecticut.

Background And Objectives: Amidst a surging national crisis of opioid use, concern has been expressed about its impact on veterans, but no study has presented a population-based comparison of opioid use disorder (OUD) among veterans and non-veterans. We analyzed national epidemiologic data to compare rates, correlates and impacts of the opioid crisis on male veterans and non-veterans.

Methods: Restricted data from 2012 to 2013 National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) were used to compare veteran and non-veteran men on rates of OUD, as well as correlates of OUD including socio-demographic characteristics, psychiatric and substance use co-morbidities, and reductions in health-related quality of life (HRQOL). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399052PMC
February 2019
4 Reads

The association of tobacco use with prescription of muscle relaxants, benzodiazepines, and opioid analgesics for non-cancer pain.

Am J Addict 2019 Feb 9;28(2):63-70. Epub 2019 Jan 9.

Department of Health Care Administration and Management, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan.

Background And Objectives: Tobacco use and co-prescription of sedative hypnotics are risk factors for misuse of prescribed opioids among patients with non-cancer pain. However, the association between tobacco use and these co-prescriptions has not been clarified. We aimed to assess differences in the prescription and co-prescription rates of opioid analgesics with muscle relaxants and/or benzodiazepines between tobacco users and non-users. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12830DOI Listing
February 2019

Issue Information - ToC.

Authors:

Am J Addict 2019 Jan;28(1)

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12849DOI Listing
January 2019

Issue Information - Editorial Board.

Authors:

Am J Addict 2019 Jan;28(1):1-2

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12848DOI Listing
January 2019

Substance use disorder and posttraumatic stress disorder symptomology on behavioral outcomes among juvenile justice youth.

Am J Addict 2019 Jan 21;28(1):29-35. Epub 2018 Dec 21.

Department of Psychology, Indiana University-Purdue University, Indianapolis, Indiana.

Background And Objectives: Substance use behaviors have been identified as a risk factor that places juveniles at greater risk for engaging in delinquent behaviors and continual contact with the juvenile justice system. Currently, there is lack of research that explores comorbid factors associated with substance use, such as post-traumatic stress disorder (PTSD) symptoms, that could help identify youth who are at greatest risk. The aim of the present study was to examine if PTSD symptomology moderated the relationship between substance use disorder (SUD) symptoms and externalizing behaviors and commission of a violent crime; hypothesizing that risk would be heightened among youth with elevated SUD and PTSD symptomology compared to those with elevated SUD symptoms but lower PTSD symptoms. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12831DOI Listing
January 2019

Expectations about alcohol, cocaine, and benzodiazepine abstinence following inpatient heroin withdrawal management.

Am J Addict 2019 Jan 12;28(1):36-42. Epub 2018 Dec 12.

Behavioral Medicine Department, Butler Hospital, Providence 02906, Rhode Island.

Background And Objectives: Polysubstance use is associated with relapse and poor treatment outcomes among people dependent on heroin. Despite the high prevalence of polysubstance use among patients detoxifying from heroin, little is known about patients' expectations to abstain or use non-opiate substances. The current study examined factors associated with expectations about abstaining from alcohol, cocaine, and benzodiazepines (BZDs) following heroin withdrawal management. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12834DOI Listing
January 2019
1 Read

Drug use and hazardous drinking are associated with PTSD symptoms and symptom clusters in US Army Reserve/National Guard Soldiers.

Am J Addict 2019 Jan 12;28(1):22-28. Epub 2018 Dec 12.

Department of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh 15213, Pennsylvania.

Background And Objectives: There is strong evidence of the association between Posttraumatic Stress Disorder (PTSD) symptoms and substance use. Previous work has found sex differences in these associations. With revisions to the DSM, it is important to understand how overall PTSD symptoms and the new symptom clusters relate to substance use among Reserve/Guard soldiers-a high risk group. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12829DOI Listing
January 2019

Neuroactive steroid levels and cocaine use chronicity in men and women with cocaine use disorder receiving progesterone or placebo.

Am J Addict 2019 Jan 11;28(1):16-21. Epub 2018 Dec 11.

The Yale Stress Center, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.

Background And Objectives: Neuroactive steroids (NAS) may play a role in addiction, with observed increases in response to acute stress and drug use, but decreases with chronic substance use, suggesting that NAS neuroadaptations may occur with chronic substance use. However, levels of NAS in addicted individuals have not been systematically examined. Here, we evaluated a panel of NAS in men and women with cocaine use disorder (CUD) who participated in a clinical laboratory study of progesterone. Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1111/ajad.12828
Publisher Site
http://dx.doi.org/10.1111/ajad.12828DOI Listing
January 2019
12 Reads

Gender differences in mental health and substance use disorders and related healthcare services utilization.

Am J Addict 2019 Jan 7;28(1):9-15. Epub 2018 Dec 7.

School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts.

Background And Objectives: Pathological gambling often co-occurs with other psychiatric disorders. Gender differences in treatment-seeking behaviors among patients with pathological gambling diagnosis remain poorly understood. This study assessed gender differences in healthcare services utilization in patients seeking treatment for pathological gambling, substance use, and mental health co-occurring conditions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12826DOI Listing
January 2019
2 Reads

Women and opioid use disorders.

Am J Addict 2018 12;27(8):646-647

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12835DOI Listing
December 2018

Attitudes toward defendants with substance-related charges: An analysis of a national sample of criminal defense attorneys.

Am J Addict 2018 12;27(8):639-645

Department of Psychology, Princeton University, Princeton, New Jersey.

Background And Objectives: While a large percentage of criminal offenders suffer from substance use disorders (SUDs), virtually nothing is known about the attitudes criminal defense attorneys possess toward their clients who are facing substance-related charges. This is a serious concern, as the burden of steering individuals with SUDs into treatment often falls to criminal defense attorneys. The goal of this study was to examine the attitudes of criminal defense attorneys toward individuals who have been accused of drug crimes. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ajad.12825
Publisher Site
http://dx.doi.org/10.1111/ajad.12825DOI Listing
December 2018
8 Reads

E-cigarettes and the Nicotine Epidemic.

Authors:
Maher Karam-Hage

Am J Addict 2018 Dec;27(8):650-651

Professor of Psychiatry and Behavioral Science Medical Director, Tobacco Treatment Program University of Texas, MD Anderson Cancer Center.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ajad.12832
Publisher Site
http://dx.doi.org/10.1111/ajad.12832DOI Listing
December 2018
12 Reads

Issue Information - Editorial Board.

Authors:

Am J Addict 2018 Dec;27(8):593-594

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12837DOI Listing
December 2018

Ayahuasca: From the Amazon to a city near you.

Authors:
J David Stiffler

Am J Addict 2018 Dec;27(8):648-649

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12833DOI Listing
December 2018

Issue Information - ToC.

Authors:

Am J Addict 2018 Dec;27(8):595-596

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12838DOI Listing
December 2018

Improving police conceptual knowledge of Mexico's law on cannabis possession: Findings from an assessment of a police education program.

Am J Addict 2018 12;27(8):608-611

Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla.

Background And Objectives: Policing practices do not reflect recent decriminalization of drug possession in Mexico. We assessed knowledge of cannabis law as part of a police education program (PEP) post-drug law reform in Tijuana.

Methods: Officers took pre-/post-PEP surveys; random subsample (n = 759) received follow-up assessments. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12827DOI Listing
December 2018

Neuropsychological changes in patients with substance use disorder after completion of a one month intensive outpatient treatment program.

Am J Addict 2018 12 2;27(8):632-638. Epub 2018 Nov 2.

Department of Psychiatry, Harvard Medical School, Boston, Massachusetts.

Background And Objectives: Data suggest individuals with substance use disorders (SUD) exhibit high rates of executive functioning (EF) impairment, and that EF level can predict treatment retention. The primary aim of the present study was to investigate if patients who completed a 1 month intensive outpatient program (IOP) for SUD demonstrated recovered EF.

Methods: Baseline and follow-up neurocognitive functioning was assessed by the Cambridge Neuropsychological Test Automated Battery (CANTAB) and the self-reported Behavior Rating Inventory of Executive Functioning (BRIEF-A) questionnaire. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ajad.12824
Publisher Site
http://dx.doi.org/10.1111/ajad.12824DOI Listing
December 2018
1 Read

Methadone to buprenorphine/naloxone induction without withdrawal utilizing transdermal fentanyl bridge in an inpatient setting-Azar method.

Am J Addict 2018 12 2;27(8):601-604. Epub 2018 Nov 2.

University of Ottawa, Ottawa, Ontario, Canada.

Background And Objectives: Although buprenorphine/naloxone is widely recognized as first-line therapy for opioid use disorder, the requirement for moderate withdrawal prior to initiation in efforts to avoid precipitated withdrawal can be a barrier to its initiation.

Methods: We present a case utilizing transdermal fentanyl as a bridging treatment to eliminate withdrawal during the transition from methadone to buprenorphine/naloxone in a patient who had ongoing significant intravenous heroin use while on methadone.

Results: Patient was successfully transitioned from methadone to buprenorphine/naloxone without a period of withdrawal utilizing transdermal fentanyl as a bridge in an inpatient setting. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12809DOI Listing
December 2018
21 Reads

Prescription opioid medication misuse among university students.

Am J Addict 2018 12 17;27(8):618-624. Epub 2018 Oct 17.

Department of Psychiatry, Behavioral Neuroscience University of Chicago, Chicago, Illinois.

Background And Objectives: Prescription opioid misuse is an established problem in the United States. Less information is known regarding the clinical and cognitive characteristics of prescription opioid misusers, specifically in a college age population. This study sought to characterize individuals who misuse prescription opioids and the differences between current, past and non-misusers. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ajad.12807
Publisher Site
http://dx.doi.org/10.1111/ajad.12807DOI Listing
December 2018
3 Reads

Commentary: The opioid overdose epidemic: Evidence-based interventions.

Authors:
Peter Barglow

Am J Addict 2018 12 12;27(8):605-607. Epub 2018 Oct 12.

Former Professor of Psychiatry, Northwestern Medical School, Chicago, Illinois.

Background And Objectives: Outcome intervention data from Medicare, veteran, prison, and United States' public populations can identify best practices to decrease opioid misuse. Prescription policies for treating pain in the United States and other countries are relevant to preventing overdose.

Methods: Three strategies are considered: (1) Demand Reduction counsels and educates patients and current or potential opioid users about risks and treatment options to reduce motivation to consume opioids. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ajad.12823
Publisher Site
http://dx.doi.org/10.1111/ajad.12823DOI Listing
December 2018
1 Read

Differences in substance use, psychiatric disorders and social factors between Mexican adolescents and young adults.

Am J Addict 2018 12 28;27(8):625-631. Epub 2018 Sep 28.

Laboratory of Neurosciences, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.

Background And Objectives: Substance use disorders (SUDs) have high comorbidities with psychiatric disorders. Childhood and adolescence are particularly vulnerable developmental periods for the onset of SUDs. The objective of this study was to explore the differences, if any, between Mexican adolescents and young adults with respect to the prevalences of groups of psychiatric disorders, the types of substances used and the social factors involved. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12808DOI Listing
December 2018
20 Reads

Expanding access to buprenorphine treatment in rural areas with the use of telemedicine.

Am J Addict 2018 12 28;27(8):612-617. Epub 2018 Sep 28.

Department of Psychiatry, School of Medicine, University of Maryland, Baltimore, Maryland.

Background And Objectives: The opioid epidemic in the United States has resulted in a public health emergency. Medication-assisted treatment (MAT) with methadone and buprenorphine are evidence-based treatments for opioid use disorder. However, numerous barriers hinder access to treatment in rural areas. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ajad.12805
Publisher Site
http://dx.doi.org/10.1111/ajad.12805DOI Listing
December 2018
16 Reads

Impulsivity and decision making in older and younger cocaine-dependent participants: A preliminary study.

Am J Addict 2018 10;27(7):557-559

Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, Virginia.

Background And Objectives: Substance misuse is increasing in the older population, which may have differing effects on behavior compared to younger substance participants. Differences in trait and state impulsivity were assessed in younger and older cocaine-dependent participants.

Methods: Thirty-one younger cocaine-dependent participants (n = 31) and 21 older cocaine-dependent participants (n = 21) were assessed using the Barrett Impulsiveness Scale-11 and the Immediate Memory Task. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211586PMC
October 2018

Trends in DMT and other tryptamine use among young adults in the United States.

Am J Addict 2018 10;27(7):578-585

Department of Population Health, New York University Langone Medical Center, New York, New York.

Background And Objectives: The popularity of tryptamines such as N,N-dimethyltryptamine (DMT) appears to be increasing in the United States (US), but epidemiologic literature on prevalence of use is scant. This paper aims to determine trends in prevalence and correlates of past-year tryptamine use among a nationally representative sample of young adults in the US.

Methods: Participants in the National Survey on Drug Use and Health survey were queried about past-year use of tryptamines-specifically DMT, α-methyltryptamine (AMT), and 5-MeO-DIPT ("Foxy"). Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ajad.12803
Publisher Site
http://dx.doi.org/10.1111/ajad.12803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182767PMC
October 2018
15 Reads

Feasibility and validity of mobile cognitive testing in patients with substance use disorders and healthy controls.

Am J Addict 2018 10;27(7):553-556

University of Bordeaux, CNRS-UMR 5287-Institut de Neurosciences Cognitives et Intégratives d'Aquitaine (INCIA), Bordeaux, France.

Background And Objectives: Mobile testing of executive deficits in substance-related addictions is highly novel but requires validation.

Methods: Sixty-one individuals (34 patients, 27 healthy controls) completed Ecological Momentary Assessments with mobile executive tests.

Results: Compliance with the tests was high (78% to 91%) in both the patient and control groups. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12804DOI Listing
October 2018
1 Read

Patterns of opioid use during initial buprenorphine/naloxone treatment in relation to changes in opioid management laws in Kentucky.

Am J Addict 2018 10 28;27(7):560-566. Epub 2018 Aug 28.

Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky.

Background And Objectives: There is limited information on the most commonly used opioid reported at the time of presentation for treatment with buprenorphine/naloxone and the extent to which state policy may impact type of opioid use reported.

Methods: Retrospective study, total N = of 595 from four different medical locations from January 1, 2009 to July 1, 2016 that provided buprenorphine/naloxone treatment in Louisville, Kentucky. Study aims included identifying the most commonly used opioid at the time of treatment before and after the creation of a state-wide opioid prescribing surveillance system (ie, the 2012 House Bill 1 [HB1]), and determine the extent to which clinical setting, sex, age, and insurance type impacted type of opioid reported during the intake appointment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12767DOI Listing
October 2018
1 Read

Substance use disorders and their effect on the psychiatric and justice systems.

Am J Addict 2018 10 28;27(7):574-577. Epub 2018 Aug 28.

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota.

Background And Objectives: A high proportion of persons in institutionalized settings such as the criminal justice system and psychiatric hospitals have substance use disorders (SUDs). We explored the association between substance use, demographics, and criminal justice involvement in a population of patients placed on involuntary 72-h holds in a psychiatric facility.

Methods: We retrospectively identified patients aged 18 through 57 years who had been placed on 72-h holds during an acute psychiatric hospitalization during a 1-year period. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12789DOI Listing
October 2018
22 Reads

Population-level patterns and mental health and substance use correlates of alcohol, marijuana, and tobacco use and co-use in US young adults and adults: Results from the population assessment for tobacco and health.

Am J Addict 2018 09;27(6):491-500

Department of Oncology, Georgetown University Medical Center, Washington, DC, District of Columbia.

Background And Objectives: This study identified the most common patterns of current alcohol and marijuana use with the spectrum of tobacco products (cigarettes, hookah, e-cigarettes, cigars/little cigars, and other products), among US young adults and older adults and examined associations of mental health and substance use problems with each pattern.

Methods: Wave 1 adult dataset (2013-2014) of the Population Assessment of Tobacco and Health (PATH) Study. Weighted analyses estimated the prevalence of the top 10 patterns of current alcohol, marijuana, and tobacco use and co-use separately by young adults aged 18-24 (n = 9,112) and adults 25+ years (n = 23,208). Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ajad.12766
Publisher Site
http://dx.doi.org/10.1111/ajad.12766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467268PMC
September 2018
23 Reads

FAAH variant Pro129Thr modulates subjective effects produced by cocaine administration.

Am J Addict 2018 10 20;27(7):567-573. Epub 2018 Aug 20.

Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas.

Background And Objectives: The endogenous cannabinoid anandamide (AEA), an agonist at type-1 cannabinoid (CB1) receptors, is metabolized by fatty acid amide hydrolase (FAAH). The common variant rs324420 C->A within the FAAH gene on chromosome 1 codes for a missense substitution (Pro129Thr), resulting in decreased FAAH activity and increased endocannabinoid potentiation. This FAAH variant has been linked to alterations in mood and stress reactivity, as well as being independently linked to increased risk for addiction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12788DOI Listing
October 2018
17 Reads

What do we know about the pharmacotheraputic management of insomnia in cannabis withdrawal: A systematic review.

Am J Addict 2018 09 16;27(6):453-464. Epub 2018 Aug 16.

Department of Psychiatry, University of Ottawa, Ontario, Canada.

Background And Objectives: Sleep disturbance is one of the hallmarks of cannabis withdrawal. Studies have indicated that treatment of this key symptom may facilitate abstinence. In the present paper we aim to provide a systematic review of the extant literature on pharmacological management of sleep disturbance associated with cannabis withdrawal. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ajad.12783
Publisher Site
http://dx.doi.org/10.1111/ajad.12783DOI Listing
September 2018
13 Reads

Gender differences in demographic and clinical characteristics of patients with opioid use disorder entering a comparative effectiveness medication trial.

Am J Addict 2018 09 14;27(6):465-470. Epub 2018 Aug 14.

Harvard Medical School Department of Psychiatry and McLean Hospital, Boston, Massachusetts.

Background & Objectives: We investigated gender differences in individuals with opioid use disorder (OUD) receiving inpatient services and entering a randomized controlled trial comparing extended-release naltrexone to buprenorphine.

Methods: Participants (N = 570) provided demographic, substance use, and psychiatric information.

Results: Women were significantly younger, more likely to identify as bisexual, live with a sexual partner, be financially dependent, and less likely employed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124662PMC
September 2018
2 Reads

Adherence to extended release naltrexone: Patient and treatment characteristics.

Am J Addict 2018 09 14;27(6):524-530. Epub 2018 Aug 14.

VA Boston Healthcare System, Boston, Massachusetts.

Background And Objectives: Despite the promise of extended release naltrexone in the treatment of the opioid and alcohol use disorders, challenges with initiation and subsequent adherence have limited its potential. The purpose of this study is to identify the patient and treatment characteristics associated with adherence to extended release naltrexone.

Methods: Retrospective cohort study of 155 veterans who initiated the medication in FY 2014 and FY2015. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajad.12786DOI Listing
September 2018
1 Read