18,627 results match your criteria American Journal Of Veterinary Research[Journal]


Quantitative characterization of viscoelastic properties of synovial fluid from forelimb joints of orthopedically normal Thoroughbreds and warmblood horses.

Am J Vet Res 2019 Apr;80(4):342-346

Objective: To determine whether differences existed in the viscoelastic properties of synovial fluid samples from the metacarpophalangeal, intercarpal, and distal interphalangeal joints of orthopedically normal athletic horses.

Animals: 45 warmblood horses and 30 Thoroughbreds (age range, 4 to 16 years).

Procedures: Synovial fluid samples were aseptically obtained via arthrocentesis from 1 metacarpophalangeal, intercarpal, and distal interphalangeal joint of each horse, and nucleated cell counts were performed. Read More

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https://avmajournals.avma.org/doi/10.2460/ajvr.80.4.342
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http://dx.doi.org/10.2460/ajvr.80.4.342DOI Listing
April 2019
4 Reads

In vitro evaluation of a medial approach for intra-articular injection of the tarsometatarsal joints of horses.

Am J Vet Res 2019 Apr;80(4):396-402

Objective: To develop a reliable method for injection of the tarsometatarsal (TMT) joint of horses through a medial approach and to characterize anatomy of the synovial recesses of the TMT joint with CT.

Sample: 13 pairs of fresh cadaveric equine tarsi.

Procedures: TMT joints were assessed with radiography and CT. Read More

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http://dx.doi.org/10.2460/ajvr.80.4.396DOI Listing
April 2019
1 Read

Hepatic computed tomography and cholangiography by use of gadoxetic acid in healthy cats.

Am J Vet Res 2019 Apr;80(4):385-395

Objective: To evaluate 3 doses of gadoxetic acid (Gd-EOB-DPTA) for hepatic CT and cholangiography in cats and to determine optimal timing for hepatobiliary image acquisition and evaluation of the contrast-enhanced hepatobiliary anatomy.

Animals: 6 healthy cats.

Procedures: Cats were anesthetized; sequential CT scans were performed 0, 5, 25, 45, 65, and 85 minutes after IV administration of Gd-EOB-DTPA at low (0. Read More

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http://dx.doi.org/10.2460/ajvr.80.4.385DOI Listing

Tikhonov gamma variate adaptive regularization applied to technetium Tc 99m diethylenetriamine pentaacetic acid plasma clearance, compared with three other methods, for measuring glomerular filtration rate in cats.

Am J Vet Res 2019 Apr;80(4):416-424

Objective: To evaluate agreement of 4 methods (Tikhonov gamma variate adaptive regularization of plasma concentration-time curve fitting applied to technetium Tc 99m diethylenetriamine pentaacetic acid [Tc-DTPA] plasma clearance [Tk-GV], plasma clearance of exogenous creatinine [CrCL], Gates gamma camera-based measurement method with Tc-DTPA renal clearance and dynamic scintigraphy [GTS], and iohexol renal clearance assessed with dynamic CT with Patlak plotting [CT-Pp]) for measuring glomerular filtration rates (GFR) in healthy cats.

Animals: 7 healthy, laboratory-raised cats.

Procedures: Each method for measuring GFR was performed twice in 7 cats at 24-day intervals. Read More

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http://dx.doi.org/10.2460/ajvr.80.4.416DOI Listing

Single-day and multiday repeatability of stance analysis results for dogs with hind limb lameness.

Am J Vet Res 2019 Apr;80(4):403-409

Objective: To assess single-day and multiday repeatability of weight distribution (stance) data obtained with a commercial analyzer for dogs with naturally occurring hind limb lameness.

Animals: 46 dogs (15 and 31 for single-day and multiday trials, respectively).

Procedures: For single-day trials, 5 to 10 measurements/trial were collected to determine body weight (BW), weight distribution on each limb, and forelimb and hind limb symmetry indices (SIs). Read More

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http://dx.doi.org/10.2460/ajvr.80.4.403DOI Listing

Biomechanical comparison of a modified three-loop pulley technique and a three-level self-locking technique for repair of patellar tendon rupture in dogs.

Am J Vet Res 2019 Apr;80(4):335-341

Objective: To compare use of a 3-level self-locking suture (3LSLS) technique with use of a previously described modified 3-loop pulley (M3LP) technique to repair rupture of the proximal aspect of patellar tendons in limbs from canine cadavers.

Sample: Paired hind limbs of 6 adult mixed-breed dogs.

Procedures: A limb from each pair was randomly assigned to be repaired by the 3LSLS technique or M3LP technique with size-2 ultrahigh-molecular-weight polyethylene and size-0 monofilament polypropylene suture, respectively. Read More

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http://dx.doi.org/10.2460/ajvr.80.4.335DOI Listing

Development and assessment of a novel precordial lead system for accurate detection of right atrial and ventricular depolarization in dogs with various thoracic conformations.

Am J Vet Res 2019 Apr;80(4):358-368

Objective: To assess recording accuracy of right atrial and ventricular depolarization during 12-lead ECG when precordial lead V was positioned at each of 5 locations on the thorax of dogs with various thoracic conformations.

Animals: 60 healthy client-owned dogs.

Procedures: 20 dogs were allocated to each of 3 groups (brachymorphic, mesomorphic, or dolichomorphic) on the basis of thoracic conformation. Read More

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http://dx.doi.org/10.2460/ajvr.80.4.358DOI Listing

Variability among strain variables derived from two-dimensional speckle tracking echocardiography in dogs by use of various software.

Am J Vet Res 2019 Apr;80(4):347-357

Objective: To determine variability of global longitudinal strain (GLS) and strain rate (SR) measurements in dogs with and without cardiac disease derived from 2-D speckle tracking echocardiography (STE) by use of various software.

Animals: 2 cohorts comprising 44 dogs (23 cardiovascularly healthy and 21 with cardiac disease) and 40 dogs (18 cardiovascularly healthy and 22 with cardiac disease).

Procedures: Transthoracic echocardiographic images in each cohort were analyzed with vendor-independent software and vendor-specific 2-D STE software for each of 2 vendors. Read More

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http://dx.doi.org/10.2460/ajvr.80.4.347DOI Listing

Effects of an enrofloxacin-silver sulfadiazine emulsion in the ears of rabbits with perforated tympanic membranes.

Am J Vet Res 2019 Apr;80(4):325-334

Objective: To determine whether an enrofloxacin-silver sulfadiazine emulsion (ESS) labeled for treatment of otitis externa in dogs has ototoxic effects in rabbits following myringotomy.

Animals: 6 healthy adult New Zealand White rabbits.

Procedures: Rabbits were anesthetized for brainstem auditory-evoked response (BAER) tests on day 0. Read More

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http://dx.doi.org/10.2460/ajvr.80.4.325DOI Listing
April 2019
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Usefulness of focused cardiac ultrasonography for predicting fluid responsiveness in conscious, spontaneously breathing dogs.

Am J Vet Res 2019 Apr;80(4):369-377

Objective: To evaluate the diagnostic usefulness of focused cardiac ultrasonography and selected echocardiographic variables for predicting fluid responsiveness in conscious, spontaneously breathing dogs with various clinical conditions.

Animals: 26 dogs (15 males and 11 females) with a median age of 84 months (range, 12 to 360 months) and median body weight of 8 kg (range, 2 to 35 kg) referred for various clinical conditions.

Procedures: Left ventricular end-diastolic internal diameter normalized to body weight (LVIDDn), left ventricular volume score (LVVS), left ventricular end-diastolic volume index (EDVI), aortic velocity time integral (VTI), and aortic peak flow velocity (Vmax) were echocardiographically measured before and after IV administration of a bolus of lactated Ringer solution (4 mL/kg) over a 1-minute period. Read More

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http://dx.doi.org/10.2460/ajvr.80.4.369DOI Listing
April 2019
1 Read

Effect of orally administered melatonin on intraocular pressure of ophthalmologically normal dogs.

Am J Vet Res 2019 Apr;80(4):410-415

Objective: To determine the effect of orally administered melatonin on the intraocular pressure (IOP) of ophthalmologically normal dogs.

Animals: 20 ophthalmologically normal dogs (40 eyes).

Procedures: In a randomized crossover study, each dog received a 7-day regimen of melatonin (0. Read More

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http://dx.doi.org/10.2460/ajvr.80.4.410DOI Listing

Evaluation of liver and spleen stiffness of healthy dogs by use of two-dimensional shear wave elastography.

Am J Vet Res 2019 Apr;80(4):378-384

Objective: To assess liver and spleen stiffness in healthy dogs by use of a novel 2-D shear wave elastography (SWE) technique and to investigate the repeatability and reproducibility of the technique.

Animals: 8 healthy adult Beagles.

Procedures: 2-D SWE was performed on each dog to assess liver and spleen stiffness. Read More

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http://dx.doi.org/10.2460/ajvr.80.4.378DOI Listing
April 2019
1 Read

Duration of β-adrenoceptor blockade associated with once-daily oral administration of atenolol in healthy dogs.

Am J Vet Res 2019 Mar;80(3):270-274

OBJECTIVE To test the hypothesis that once-daily oral administration of atenolol would attenuate the heart rate response to isoproterenol for 24 hours. ANIMALS 20 healthy dogs. PROCEDURES A double-blind randomized placebo-controlled crossover study was conducted. Read More

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http://dx.doi.org/10.2460/ajvr.80.3.270DOI Listing

Effects of ventilation mode and blood flow on arterial oxygenation during pulse-delivered inhaled nitric oxide in anesthetized horses.

Am J Vet Res 2019 Mar;80(3):275-283

OBJECTIVE To determine the impact of mechanical ventilation (MV) and perfusion conditions on the efficacy of pulse-delivered inhaled nitric oxide (PiNO) in anesthetized horses. ANIMALS 27 healthy adult horses. PROCEDURES Anesthetized horses were allocated into 4 groups: spontaneous breathing (SB) with low (< 70 mm Hg) mean arterial blood pressure (MAP; group SB-L; n = 7), SB with physiologically normal (≥ 70 mm Hg) MAP (group SB-N; 8), MV with low MAP (group MV-L; 6), and MV with physiologically normal MAP (group MV-N; 6). Read More

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http://dx.doi.org/10.2460/ajvr.80.3.275DOI Listing

Evaluation of diagnostic coelioscopy in koi (Cyprinus carpio).

Am J Vet Res 2019 Mar;80(3):221-229

OBJECTIVE To describe a technique for endoscopic evaluation of the coelomic viscera of koi (Cyprinus carpio) and to evaluate the ability to visually examine coelomic structures by use of an approach cranial or caudal to the pelvic girdle. ANIMALS 16 subadult koi. PROCEDURES Koi were anesthetized with buffered tricaine methanesulfonate. Read More

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http://dx.doi.org/10.2460/ajvr.80.3.221DOI Listing

Comparison of three walkway cover types for use during objective canine gait analysis with a pressure-sensitive walkway.

Am J Vet Res 2019 Mar;80(3):265-269

OBJECTIVE To compare the effects of 3 walkway cover types on temporospatial and ground reaction force measurements of dogs during gait analysis with a pressure-sensitive walkway (PSW). ANIMALS 35 client- and staff-owned dogs (25 nonlame and 10 lame). PROCEDURES In a crossover study design, all dogs were evaluated at a comfortable walk on a PSW to which 3 cover types (a 0. Read More

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http://dx.doi.org/10.2460/ajvr.80.3.265DOI Listing

Evaluation of lipid markers in surfactant obtained from asthmatic horses exposed to hay.

Am J Vet Res 2019 Mar;80(3):300-305

OBJECTIVE To evaluate the lipidomic profile of surfactant obtained from horses with asthma at various clinical stages and to compare results with findings for healthy horses exposed to the same conditions. SAMPLE Surfactant samples obtained from 6 horses with severe asthma and 7 healthy horses. PROCEDURES Clinical evaluation of horses and surfactant analysis were performed. Read More

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http://dx.doi.org/10.2460/ajvr.80.3.300DOI Listing

Randomized blinded controlled trial of dipyrone as a treatment for pyrexia in horses.

Am J Vet Res 2019 Mar;80(3):294-299

OBJECTIVE To evaluate the effectiveness and safety of dipyrone to control pyrexia in horses with naturally occurring disease under field conditions. ANIMALS 138 horses with pyrexia and various infections evaluated at 14 veterinary sites in 12 states. PROCEDURES In the first (effectiveness) phase of this 2-phase study, horses were randomly assigned 3:1 to receive 1 dose of dipyrone (30 mg/kg [13. Read More

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https://avmajournals.avma.org/doi/10.2460/ajvr.80.3.294
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http://dx.doi.org/10.2460/ajvr.80.3.294DOI Listing
March 2019
3 Reads

Lactate and glucose thresholds and heart rate deflection points for Beagles during intense exercise.

Am J Vet Res 2019 Mar;80(3):284-293

OBJECTIVE To determine whether the lactate threshold of dogs could be determined by a visual method and to assess the extent of agreement and bias among treadmill velocities for the lactate threshold as determined by visual (LTv) and polynomial (LTp) methods, glucose threshold as determined by visual (GTv) and polynomial (GTp) methods, and heart rate deflection point (HRdp) as a method for estimating the aerobic capacity of dogs. ANIMALS 18 healthy adult Beagles. PROCEDURES Each dog underwent a standardized incremental treadmill exercise test once. Read More

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http://dx.doi.org/10.2460/ajvr.80.3.284DOI Listing
March 2019
1 Read

Pharmacokinetics after subcutaneous administration of a single dose of cefovecin sodium in African lions (Panthera leo).

Am J Vet Res 2019 Mar;80(3):230-234

OBJECTIVE To determine the pharmacokinetics of cefovecin sodium after SC administration of a single dose to African lions (Panthera leo). ANIMALS 3 adult (9 to 10 years old; 1 male and 2 females) and 3 juvenile (2 years old; 1 male and 2 females) African lions. PROCEDURES A crossover study was conducted. Read More

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http://dx.doi.org/10.2460/ajvr.80.3.230DOI Listing

Effects of flunixin meglumine on postponement of ovulation in mares.

Am J Vet Res 2019 Mar;80(3):306-310

OBJECTIVE To evaluate use of flunixin meglumine as a treatment to postpone ovulation in mares, mare fertility after flunixin meglumine treatment during estrous cycles, and effects of flunixin meglumine on function of the corpus luteum after ovulation. ANIMALS 13 healthy mares. PROCEDURES A single-blinded, placebo-controlled, crossover study was conducted. Read More

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http://dx.doi.org/10.2460/ajvr.80.3.306DOI Listing

Ex vivo computed tomography evaluation of loading position on morphometry of the caudal cervical intervertebral disk spaces of dogs.

Am J Vet Res 2019 Mar;80(3):235-245

OBJECTIVE To provide an objective, quantitative morphometric description of the caudal cervical intervertebral disk (IVD) spaces of dogs. SAMPLE Vertebral specimens consisting of C4 through C7 from 5 medium-sized dogs. PROCEDURES CT images were obtained with the specimens positioned in neutral, flexion, extension, and lateral bending positions. Read More

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http://dx.doi.org/10.2460/ajvr.80.3.235DOI Listing

Evaluation of an osteochondral fragment-groove procedure for induction of metacarpophalangeal joint osteoarthritis in horses.

Am J Vet Res 2019 Mar;80(3):246-258

OBJECTIVE To evaluate lameness and morphological changes associated with an osteochondral fragment-groove procedure as a means of experimental induction of metacarpophalangeal (MCP) joint osteoarthritis within an 11-week period in horses. ANIMALS 6 nonlame adult warmbloods. PROCEDURES The right MCP joint of each horse underwent an osteochondral fragment-groove procedure (day 0). Read More

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http://dx.doi.org/10.2460/ajvr.80.3.246DOI Listing
March 2019
1 Read

Development and analytic validation of a sandwich ELISA for the measurement of α-proteinase inhibitor concentrations in serum and feces of common marmosets (Callithrix jacchus).

Am J Vet Res 2019 Mar;80(3):259-264

OBJECTIVE To develop and validate a sandwich ELISA for the measurement of α-proteinase inhibitor (α-PI) concentrations in serum and fecal samples obtained from common marmosets (Callithrix jacchus). SAMPLE Leftover serum (n = 42) and fecal (23) samples submitted for diagnostic testing; paired serum and fecal samples obtained from 30 common marmosets at 2 research colonies. PROCEDURES A sandwich ELISA was developed and analytically validated by determining the lower limit of detection, linearity, accuracy, precision, and reproducibility. Read More

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http://dx.doi.org/10.2460/ajvr.80.3.259DOI Listing

Pharmacokinetics and safety of zonisamide after oral administration of single and multiple doses to Hispaniolan Amazon parrots (Amazona ventralis).

Am J Vet Res 2019 Feb;80(2):195-200

OBJECTIVE To determine pharmacokinetics after oral administration of single and multiple doses and to assess the safety of zonisamide in Hispaniolan Amazon parrots (Amazona ventralis). ANIMALS 12 adult Hispaniolan Amazon parrots. PROCEDURES Zonisamide (30 mg/kg, PO) was administered once to 6 parrots in a single-dose trial. Read More

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http://dx.doi.org/10.2460/ajvr.80.2.195DOI Listing
February 2019
1 Read

Histologic assessment of ligament vascularity and synovitis in dogs with cranial cruciate ligament disease.

Am J Vet Res 2019 Feb;80(2):152-158

Objective: To assess the relationship between histologic degeneration of cranial cruciate ligaments (CCLs) and severity of synovitis and ligament vascularity.

Sample: CCL and synovium from 59 stifle joints (53 dogs).

Procedures: CCL and synovium specimens were obtained from stifle joints of juvenile (15 joints; 12 dogs) and adult (25 joints; 22 dogs) dogs with intact CCLs and dogs with CCL rupture (rCCL; 19 joints; 19 dogs). Read More

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http://dx.doi.org/10.2460/ajvr.80.2.152DOI Listing
February 2019

Comparison of computed tomographic attenuation values for epaxial muscles in old and young dogs.

Am J Vet Res 2019 Feb;80(2):174-177

OBJECTIVE To determine whether the degree of CT attenuation of muscle would differ between healthy old and young dogs. ANIMALS 10 healthy old (> 8 years old) and 9 healthy young (1 to 5 years old) Labrador Retrievers with a body condition score of 5 or 6 on a 9-point scale. PROCEDURES CT was performed with the dogs mildly sedated. Read More

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http://dx.doi.org/10.2460/ajvr.80.2.174DOI Listing
February 2019

Effect of contrast medium injection rate on computed tomography-derived renal perfusion estimates obtained with the maximum slope method in healthy.

Am J Vet Res 2019 Feb;80(2):168-173

OBJECTIVE To evaluate the effect of contrast medium injection rate on CT-derived renal perfusion estimates obtained with the maximum slope method in healthy small dogs. ANIMALS 6 healthy sexually intact male purpose-bred Beagles. PROCEDURES All dogs underwent CT perfusion analysis 3 times in a crossover design, receiving a different contrast medium injection rate (1. Read More

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http://dx.doi.org/10.2460/ajvr.80.2.168DOI Listing
February 2019
1 Read

Pharmacokinetics of meloxicam during multiple oral or intramuscular dose administration to African grey parrots (Psittacus erithacus).

Am J Vet Res 2019 Feb;80(2):201-207

OBJECTIVE To determine the pharmacokinetics of meloxicam in African grey parrots (Psittacus erithacus) during administration of multiple doses. ANIMALS 6 healthy African grey parrots. PROCEDURES Meloxicam was administered at each of 3 dosages (1 mg/kg, IM, q 24 h, for 7 days; 1 mg/kg, PO, q 24 h, for 12 days; and 1. Read More

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http://dx.doi.org/10.2460/ajvr.80.2.201DOI Listing
February 2019
1 Read

Evaluation of the effects of gas volume and composition on accuracy of volume measurement by two flow sensors and delivery by a piston-driven large-animal ventilator.

Am J Vet Res 2019 Feb;80(2):135-143

OBJECTIVE To evaluate the effects of 4 gas compositions at various volumes (simulated tidal volumes [Vs]) on accuracy of measurements obtained with 2 types of flow sensors and accuracy of gas volume delivery by a piston-driven ventilator. SAMPLE 4 gas mixtures (medical air [21% O:79% N], > 95% O, O-enriched air [30% O:70% N], and heliox [30% O:70% He]). PROCEDURES For each gas mixture, reference Vs of 1 to 8 L were delivered into an anesthetic breathing circuit via calibration syringe; measurements recorded by a Pitot tube-based flow sensor (PTFS) connected to a multiparameter host anesthesia monitor and by a thermal mass flow and volume meter (TMFVM) were compared with the reference values. Read More

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http://dx.doi.org/10.2460/ajvr.80.2.135DOI Listing
February 2019
10 Reads

Effect of intracoelomic administration of alfaxalone on the righting reflex and tactile stimulus response of common garter snakes (Thamnophis sirtalis).

Am J Vet Res 2019 Feb;80(2):144-151

Objective: To determine the intracoelemic (ICe) dose of alfaxalone required to induce loss of righting reflex (LRR) in garter snakes (Thamnophis sirtalis) and to evaluate the tactile stimulus response in unanesthetized and alfaxalone-anesthetized snakes.

Animals: 8 healthy mature garter snakes.

Procedures: During the first of 3 phases, snakes received each of 3 doses (10, 20, and 30 mg/kg) of alfaxalone, ICe, with a 2-week washout period between treatments. Read More

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http://dx.doi.org/10.2460/ajvr.80.2.144DOI Listing
February 2019

Relationship between breed, hemivertebra subtype, and kyphosis in apparently neurologically normal French Bulldogs, English Bulldogs, and Pugs.

Am J Vet Res 2019 Feb;80(2):189-194

OBJECTIVE To investigate whether hemivertebra subtype as determined via CT was associated with breed and Cobb angle (a measure of the degree of spinal curvature) in apparently neurologically normal French Bulldogs, English Bulldogs, and Pugs. ANIMALS Client-owned French Bulldogs (n = 58), English Bulldogs (30), and Pugs (12) with thoracic hemivertebrae that underwent CT for reasons unrelated to spinal disease. PROCEDURES CT scans of each dog were evaluated, and hemivertebrae were categorized by subtype (ventral aplasia, ventral hypoplasia, lateral aplasia, lateral hypoplasia, ventrolateral aplasia, ventrolateral hypoplasia, ventral and median aplasia, ventral and median hypoplasia, and symmetric hypoplasia). Read More

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https://avmajournals.avma.org/doi/10.2460/ajvr.80.2.189
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http://dx.doi.org/10.2460/ajvr.80.2.189DOI Listing
February 2019
1 Read

Evaluation of skin turgor and capillary refill time as predictors of dehydration in exercising dogs.

Am J Vet Res 2019 Feb;80(2):123-128

OBJECTIVE To determine usefulness of skin turgor and capillary refill time (CRT) for predicting changes in hydration status of working dogs after a 15-minute exercise period. ANIMALS 9 exercise-conditioned working dogs between 8 and 108 months of age. PROCEDURES Skin tent time (SkTT; time for tented skin on the forehead to return to an anatomically normal position) and CRT (time for occluded mucous membrane capillary vessels to return to the color visible before occlusion) were measured on dogs in a field setting and by video review. Read More

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http://dx.doi.org/10.2460/ajvr.80.2.123DOI Listing
February 2019

Association of catastrophic condylar fracture with bony changes of the third metacarpal bone identified by use of standing magnetic resonance imaging in forelimbs from cadavers of Thoroughbred racehorses in the United States.

Am J Vet Res 2019 Feb;80(2):178-188

OBJECTIVE To compare bony changes of the third metacarpal bone (MC3) of Thoroughbred racehorse cadavers with (cases) or without (controls) catastrophic condylar fracture by use of standing MRI. SAMPLE 140 forelimbs from 26 case horses (both forelimbs) and 88 control horses (single forelimb). PROCEDURES Bone marrow lesions (BMLs), identified as a decrease in T1-weighted (T1W) signal and increases in T2*-weighted (T2*W) and short tau inversion recovery (STIR) signals, and dense bone volume percentage (DBVP), identified as decreases in T1W, T2*W, and STIR signals, in the distopalmar aspect of MC3 were recorded. Read More

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http://dx.doi.org/10.2460/ajvr.80.2.178DOI Listing
February 2019
2 Reads

Effects of the fraction of inspired oxygen on alfaxalone-sedated inland bearded dragons (Pogona vitticeps).

Am J Vet Res 2019 Feb;80(2):129-134

OBJECTIVE To evaluate the effects of providing 100% O, compared with provision of room air, in sedated spontaneously breathing inland bearded dragons (Pogona vitticeps). ANIMALS 8 adult bearded dragons. PROCEDURES Animals were sedated with alfaxalone (20 mg/kg, SC) and received 21% O (equivalent to room air) or 100% O via face mask (flow rate, 1 L/min) in a randomized, blinded, complete crossover study (2-week interval between treatments). Read More

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https://avmajournals.avma.org/doi/10.2460/ajvr.80.2.129
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http://dx.doi.org/10.2460/ajvr.80.2.129DOI Listing
February 2019
12 Reads

Perfusion-weighted and diffusion-weighted magnetic resonance imaging of the liver, spleen, and kidneys of healthy adult male cats.

Am J Vet Res 2019 Feb;80(2):159-167

OBJECTIVE To describe perfusion and diffusion characteristics of the liver, spleen, and kidneys of healthy adult male cats as determined by morphological, perfusion-weighted, and diffusion-weighted MRI. ANIMALS 12 healthy adult male cats. PROCEDURES Each cat was anesthetized. Read More

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http://dx.doi.org/10.2460/ajvr.80.2.159DOI Listing
February 2019
2 Reads

Reference limits for hepatic bile duct-to-arteriole and bile duct-to-portal tract ratios in healthy cats.

Am J Vet Res 2019 Jan;80(1):15-23

OBJECTIVE To establish reference limits for hepatic bile duct-to-arteriole ratio (BD:A) and bile duct-to-portal tract ratio (BD:PT) in healthy cats and assess whether these parameters could be used to support a diagnosis of biliary ductopenia in cats. SAMPLE Hepatic biopsy samples from healthy cats (n = 20) and cats with ductopenia (2). PROCEDURES Hepatic biopsy samples from healthy cats were used to count the number of bile ducts and hepatic arterioles in 20 portal tracts for each cat. Read More

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http://dx.doi.org/10.2460/ajvr.80.1.15DOI Listing
January 2019
1 Read

Use of a modified passive leg-raising maneuver to predict fluid responsiveness during experimental induction and correction of hypovolemia in healthy isoflurane-anesthetized pigs.

Am J Vet Res 2019 Jan;80(1):24-32

OBJECTIVE To evaluate the use of a modified passive leg-raising maneuver (PLRM) to predict fluid responsiveness during experimental induction and correction of hypovolemia in isoflurane-anesthetized pigs. ANIMALS 6 healthy male Landrace pigs. PROCEDURES Pigs were anesthetized with isoflurane, positioned in dorsal recumbency, and instrumented. Read More

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https://avmajournals.avma.org/doi/10.2460/ajvr.80.1.24
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http://dx.doi.org/10.2460/ajvr.80.1.24DOI Listing
January 2019
3 Reads

Investigation of effects of omeprazole on the fecal and gastric microbiota of healthy adult horses.

Am J Vet Res 2019 Jan;80(1):79-86

OBJECTIVE To determine the effects of oral omeprazole administration on the fecal and gastric microbiota of healthy adult horses. ANIMALS 12 healthy adult research horses. PROCEDURES Horses were randomly assigned to receive omeprazole paste (4 mg/kg, PO, q 24 h) or a sham (control) treatment (tap water [20 mL, PO, q 24 h]) for 28 days. Read More

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http://dx.doi.org/10.2460/ajvr.80.1.79DOI Listing
January 2019
2 Reads

Morphometric evaluation of the portal vein by means of abdominal computed tomographic angiography in dogs free of vascular anomalies.

Am J Vet Res 2019 Jan;80(1):69-73

OBJECTIVE To determine the mean diameter of the main portal vein (PV) in healthy dogs by use of CT angiography, identify any associations between PV diameter and certain dog characteristics, and validate a clinically valuable ratio for quantifying the size of the PV. ANIMALS 100 dogs with no hepatic, cardiac, or vascular anomalies that underwent abdominal CT angiography. PROCEDURES Diameters of the main PV, abdominal aorta (Ao), and caudal vena cava (CVC) were measured by 2 observers at a defined location on postcontrast CT angiographic images in axial, sagittal, and transverse planes. Read More

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http://dx.doi.org/10.2460/ajvr.80.1.69DOI Listing
January 2019
1 Read

Determination of the pharmacokinetics of a single oral dose of trazodone and its effect on the activity level of domestic pigeons (Columba livia).

Am J Vet Res 2019 Jan;80(1):102-109

Objective: To determine the pharmacokinetics of a single oral dose of trazodone and its effect on the activity of domestic pigeons (Columba livia).

Animals: 6 healthy adult male domestic pigeons.

Procedures: During the first of 3 experiments, birds received orally administered trazodone at doses ranging from 3 to 30 mg/kg to determine the dose for subsequent experiments. Read More

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http://dx.doi.org/10.2460/ajvr.80.1.102DOI Listing
January 2019
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JAVMA New digest.

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Am J Vet Res 2019 Jan;80(1):4-9

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https://avmajournals.avma.org/doi/10.2460/ajvr.80.1.4
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http://dx.doi.org/10.2460/ajvr.80.1.4DOI Listing
January 2019
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Effect of acute volume overload on echocardiographic indices of right ventricular function and dyssynchrony assessed by use of speckle tracking echocardiography in healthy dogs.

Am J Vet Res 2019 Jan;80(1):51-60

OBJECTIVE To determine the relationship between acute volume overload and echocardiographic indices of right ventricular (RV) function and dyssynchrony in healthy dogs. ANIMALS 7 healthy Beagles. PROCEDURES Right heart catheterization and echocardiography were performed in 7 healthy anesthetized Beagles at baseline and after induction of volume overload. Read More

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https://avmajournals.avma.org/doi/10.2460/ajvr.80.1.51
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http://dx.doi.org/10.2460/ajvr.80.1.51DOI Listing
January 2019
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Changes in pupil size and intraocular pressure after topical application of 0.5% tropicamide to the eyes of dogs sedated with butorphanol.

Am J Vet Res 2019 Jan;80(1):95-101

Objective: To assess changes in pupil size and intraocular pressure (IOP) following topical application of a 0.5% tropicamide solution in the eyes of healthy butorphanol-sedated dogs.

Animals: 12 healthy adult Beagles. Read More

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http://dx.doi.org/10.2460/ajvr.80.1.95DOI Listing
January 2019
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In vitro effect of 20% N-acetylcysteine on the viscosity of normal canine bile.

Am J Vet Res 2019 Jan;80(1):74-78

OBJECTIVE To evaluate the in vitro effect of 20% N-acetylcysteine (NAC) on the viscosity of normal canine bile. ANIMALS Bile samples obtained from 10 adult dogs euthanized for reasons unrelated to biliary disease. PROCEDURES Each sample was centrifuged to remove particulates, then divided into 3 aliquots. Read More

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https://avmajournals.avma.org/doi/10.2460/ajvr.80.1.74
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http://dx.doi.org/10.2460/ajvr.80.1.74DOI Listing
January 2019
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Esophageal insufflation computed tomography in clinically normal dogs.

Am J Vet Res 2019 Jan;80(1):61-68

OBJECTIVE To assess the feasibility of esophageal insufflation CT (EICT) for evaluation of the esophagus in dogs. ANIMALS 7 clinically normal adult Beagles. PROCEDURES Each dog was anesthetized twice with 1 week between anesthesia sessions. Read More

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https://avmajournals.avma.org/doi/10.2460/ajvr.80.1.61
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http://dx.doi.org/10.2460/ajvr.80.1.61DOI Listing
January 2019
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Effects of intravenous administration of tiletamine-zolazepam, alfaxalone, ketamine-diazepam, and propofol for induction of anesthesia on cardiorespiratory and metabolic variables in healthy dogs before and during anesthesia maintained with isoflurane.

Am J Vet Res 2019 Jan;80(1):33-44

OBJECTIVE To compare effects of tiletamine-zolazepam, alfaxalone, ketamine-diazepam, and propofol for anesthetic induction on cardiorespiratory and acid-base variables before and during isoflurane-maintained anesthesia in healthy dogs. ANIMALS 6 dogs. PROCEDURES Dogs were anesthetized with sevoflurane and instrumented. Read More

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http://dx.doi.org/10.2460/ajvr.80.1.33DOI Listing
January 2019
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Evaluation of vaporized hydrogen peroxide sterilization on the in vitro efficacy of meropenem-impregnated polymethyl methacrylate beads.

Am J Vet Res 2019 Jan;80(1):45-50

OBJECTIVE To evaluate the effects of vaporized hydrogen peroxide (VHP) sterilization on the in vitro antimicrobial efficacy of meropenem-impregnated polymethyl methacrylate (M-PMMA) beads. SAMPLE 6-mm-diameter polymethyl methacrylate beads that were or were not impregnated with meropenem. PROCEDURES Meropenem-free polymethyl methacrylate and M-PMMA beads were sterilized by use of an autoclave or VHP or remained unsterilized. Read More

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http://dx.doi.org/10.2460/ajvr.80.1.45DOI Listing
January 2019
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