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Am J Med Sci 2020 Apr 29. Epub 2020 Apr 29.

Am J Med Sci 2020 Apr 2. Epub 2020 Apr 2.

Department of Hematology/Oncology, Saint Joseph University Medical Center, Paterson, New Jersey.

Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is an X-linked genetic disorder associated with intravascular hemolysis. Rhabdomyolysis with myoglobinuria in a patient with G6PD deficiency is a very rare manifestation, in fact, to the best of our knowledge, only a few case reports have been published in the literature to date. Herein, we report an unusual presentation of a 33-year-old male with G6PD deficiency with multiple episodes of severe rhabdomyolysis with no significant concurrent hemolysis. Read More

Am J Med Sci 2020 Apr 29. Epub 2020 Apr 29.

Am J Med Sci 2020 May 12. Epub 2020 May 12.

Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address:

Am J Med Sci 2020 May 11. Epub 2020 May 11.

Department of Gastroenterology, Eastern Health, Box Hill, Victoria, Australia.

Am J Med Sci 2020 Apr 29. Epub 2020 Apr 29.

Am J Med Sci 2020 May 5. Epub 2020 May 5.

Department of Hematology-Oncology, St. Joseph's University Medical Center, Paterson, New Jersey.

Am J Med Sci 2020 May 4. Epub 2020 May 4.

Division of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. Electronic address:

Background: Nonalcoholic fatty liver disease (NAFLD) is regarded as a feature of metabolic syndrome in the liver. Metabolic syndrome is associated with a higher risk of bladder cancer. However, the association between NAFLD and bladder cancer is unclear. Read More

Am J Med Sci 2020 Apr 29. Epub 2020 Apr 29.

Am J Med Sci 2020 Apr 25. Epub 2020 Apr 25.

Medical Scientific Research Center, Guangxi Medical University, Nanning, Guangxi, China; Scientific Research Center, Guilin Medical University, Nanning, Guilin, China. Electronic address:

Background: Cystic fibrosis transmembrane conductance regulator IVS8-5T gene variation appears to be associated with a higher risk of chronic pancreatitis (CP); however, there is inconsistency between previous reported studies. Here, we performed a meta-analysis to investigate this relationship.

Materials And Methods: PubMed and WANFANG databases were searched for the case-control studies that contained Patients with CP with IVS8-5T variation. Read More

Am J Med Sci 2020 Apr 15. Epub 2020 Apr 15.

Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas. Electronic address:

Am J Med Sci 2020 Apr 25. Epub 2020 Apr 25.

Department of Diagnostic and Generalist Medicine, Dokkyo Medical University, Mibu-cho, Simotsuga-gun Tochigi, Japan.

Am J Med Sci 2020 Apr 28. Epub 2020 Apr 28.

Am J Med Sci 2020 Apr 27. Epub 2020 Apr 27.

Azrieli Faculty of Medicine, Bar Ilan University, Ramat Gan, Israel.

Am J Med Sci 2020 Apr 17. Epub 2020 Apr 17.

Dornsife School of Public Health, Drexel University, Philadelphia, Pennsylvania. Electronic address:

Am J Med Sci 2020 Apr 17. Epub 2020 Apr 17.

Department of Diagnostic Radiology, Cleveland Clinic, Cleveland, Ohio.

Am J Med Sci 2020 Apr 10. Epub 2020 Apr 10.

Department of Geriatric Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People's Republic of China. Electronic address:

Background: The association between uric acid and N-Terminal Pro-B-Type Natriuretic Peptide (NT-proBNP) in patients with unstable angina pectoris (UAP) is unclear.

Methods: We recruited 260 patients with UAP admitted to the first affiliated Hospital of Guangxi Medical University from February 2018 to August 2018. According to the level of uric acid, patients were divided into 4 groups (Q1 = 48. Read More

Am J Med Sci 2020 Apr 29. Epub 2020 Apr 29.

Am J Med Sci 2020 Apr 25. Epub 2020 Apr 25.

Department of Internal Medicine, Kyungpook National University, School of Medicine, Daegu, Republic of Korea. Electronic address:

Background: The etiology of pleural effusions often remained unknown notwithstanding surgical pleural biopsy and further clinical observation. A better understanding of clinical characteristics of patients with idiopathic pleural effusion (IPE) may improve the ability to differentiate between IPEs and cytology-negative malignant pleural effusions (MPEs) and facilitate the identification of patients requiring invasive investigation. However, little is known about the clinical factors that can help distinguish patients with IPE from those with cytology-negative MPE. Read More

Am J Med Sci 2020 Apr 25. Epub 2020 Apr 25.

ENT Department, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China. Electronic address:

Background: At present, the effect of operation intervention on pulmonary function is not clear in patients with allergic rhinitis and chronic rhinosinusitis with nasal polyps (AR&CRSwNP). This study was conducted to investigate the effect of vidian neurectomy on pulmonary function and airway hyperresponsiveness (AHR) in patients with AR&CRSwNP.

Methods: The incidences of AHR, bronchial asthma (BA) and pulmonary function impairment in 112 patients with AR&CRSwNP were investigated. Read More

Am J Med Sci 2020 Apr 28. Epub 2020 Apr 28.

Department of Pulmonary and Critical Care Medicine, First Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi, China.

Am J Med Sci 2020 Apr 26. Epub 2020 Apr 26.

Division of Cardiovascular Medicine, University of Toledo, Toledo, Ohio. Electronic address:

Am J Med Sci 2020 Apr 27. Epub 2020 Apr 27.

Department of Neurosurgery, St Lukas Hospital, Tarnów, Poland. Electronic address:

Am J Med Sci 2020 Apr 18. Epub 2020 Apr 18.

Department of Dentistry and Oral Surgery, Unit of Sensory and Locomotor Medicine, Division of Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.

Am J Med Sci 2020 Apr 10. Epub 2020 Apr 10.

Department of Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Tzu Chi University, Hualien, Taiwan. Electronic address:

Am J Med Sci 2020 Apr 14. Epub 2020 Apr 14.

Assistenza Anziani, ASL Avellino, Avellino, Italy.

Women with acute myocardial infarction (AMI) have poorer clinical outcomes than men. Elderly women present high risk of developing frailty and frail women with AMI have a higher prevalence of functional impairments than men on presentation, including physical and cognitive impairment. The Mini-Mental State Examination is a simple test that evaluates global cognitive functions. Read More

Am J Med Sci 2020 Apr 11. Epub 2020 Apr 11.

Division of Hematology/Oncology, Department of Medicine, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, Maryland; Division of Blood and Marrow Transplant Program, Department of Medicine, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, Maryland.

Am J Med Sci 2020 Apr 17. Epub 2020 Apr 17.

Department of Renal Pathology, King Medical Diagnostics Center, Guangzhou, China.

Immunoglobulin A (IgA) nephropathy is one of the most common glomerulonephritis characterized by the deposition of IgA in glomerular mesangium. Karyomegalic interstitial nephritis (KIN) is a rare interstitial nephritis with potential hereditary factors. IgA nephropathy concomitant with KIN has not yet been reported. Read More

Am J Med Sci 2020 Apr 12. Epub 2020 Apr 12.

Division of Gastroenterology, Texas Tech University Health Sciences Center, El Paso, TX. Electronic address:

Background: Rumination syndrome is a functional gastrointestinal disorder characterized by effortless postprandial regurgitation and accompanied by gastric visceral hypersensitivity. Almost invariably, the onset of symptoms is preceded by a psychologically stressful situation, and anxiety is often an accompanying complaint. In this background of gastric visceral hypersensitivity, anxiety and psychological stress, we investigated the effectiveness of combining a tricyclic antidepressant (TCA) with diaphragmatic breathing/relaxation techniques for the treatment of rumination syndrome. Read More

Am J Med Sci 2020 Apr 11. Epub 2020 Apr 11.

Center for Diabetes, Endocrinology, and Metabolism, Toho University Sakura Medical Center, Chiba, Japan. Electronic address:

Background: Diabetes carries a known risk of bone fracture despite high bone mineral density (BMD). The fracture risk assessment tool (FRAX) predicts the 10-year major osteoporotic fracture risk and hip fracture risk. We investigated the effects of clinical parameters on the FRAX score and evaluated the validity of FRAX for evaluating current bone fragility in diabetes subjects. Read More

Am J Med Sci 2020 Apr 17. Epub 2020 Apr 17.

College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee. Electronic address:

Background: Traditionally, the antibiotic of choice for Methicillin-susceptible Staphylococcus aureus related blood stream infections (MSSA-BSI) are the antistaphylococcal penicillins. Cefazolin is considered an alternative agent, with recent evidence showing similar clinical efficacy. This study further evaluates the utility of nafcillin versus cefazolin in MSSA bacteremia including high disease burden sources of infection and its impact on treatment failure. Read More

Am J Med Sci 2020 May 13;359(5):287-295. Epub 2020 Mar 13.

Department of Radiation Oncology and Medical Oncology, Zhongnan Hospital of Wuhan University, Hubei Cancer Clinical Study Center, Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China. Electronic address:

Background: Gastric cancer is one of the most aggressive tumors, usually resulting in metastasis, and therapies for advanced gastric cancer remain limited. Drug resistance is the main reason for chemotherapeutic failure in gastric cancer. Wiskott-Aldrich syndrome protein family member 3 (WASF3) is required for invasion and metastasis of different cancers. Read More

Am J Med Sci 2020 May 9;359(5):266-270. Epub 2020 Mar 9.

Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee; General Clinical Research Center, University of Tennessee Health Science Center, Memphis, Tennessee. Electronic address:

Background: Cross-sectional surveys report a higher prevalence of diagnosed type 2 diabetes mellitus (T2DM) in African Americans (AA) than European Americans (EA). We studied 5-year glycemic excursions among AA and EA in the Pathobiology of Prediabetes in A Biracial Cohort study, to assess ethnic disparities.

Materials And Methods: Pathobiology of Prediabetes in A Biracial Cohort followed normoglycemic offspring of parents with T2DM for 5 years, with serial assessments of oral glucose tolerance test , anthropometry, body fat, insulin sensitivity and beta-cell function. Read More

Am J Med Sci 2020 May 12;359(5):255-256. Epub 2020 Mar 12.

Departments of Medicine, Radiology and Population Health Sciences, Medical College of Georgia, Augusta, GA.

Am J Med Sci 2020 Apr 5. Epub 2020 Apr 5.

Cellular and Molecular Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran. Electronic address:

Background: CD19IL-10B cells are considered as a particular subset of immunosuppressive cells by producing interleukin 10 (IL-10), which plays an important role in infectious and autoimmune diseases. The aim of this study was to determine the number of CD19IL-10B cells in Helicobacter pylori (H. pylori) positive patients in comparison with H. Read More

Am J Med Sci 2020 Mar 11. Epub 2020 Mar 11.

Quillen College of Medicine and Washington University of St. Louis, St. Louis, Missouri. Electronic address:

Background: Patients with left ventricular ejection fractions between 40% and 49% either discovered de novo, having declined from ≥50%, or improved from <40% have been described as heart failure (HF) with mid-range ejection fraction (HFmrEF). Though clinical signs and symptoms are similar to other phenotypes, possible prognostic differences and therapeutic responses reinforce the need for further understanding of patients' characteristics especially in a rural community based population. The purpose of this study is to evaluate the clinical characteristics, comorbidities and prognosis of a rural patient population with HFmrEF. Read More

Am J Med Sci 2020 Mar 19. Epub 2020 Mar 19.

Department of Dermatology, Venereology, and Leprosy, R.G. Kar Medical College, Kolkata, West Bengal, India.

Am J Med Sci 2020 Mar 19. Epub 2020 Mar 19.

Division of Critical Care Nursing, Albany Medical Center College, Albany, New York. Electronic address:

Am J Med Sci 2020 Mar 19. Epub 2020 Mar 19.

Department of Internal Medicine, Section on Gastroenterology, Wake Forest Baptist Health, Winston-Salem, North Carolina.

Am J Med Sci 2020 Mar 18. Epub 2020 Mar 18.

Department of Internal Medicine and Division of Hematology/Oncology, Chungnam National University College of Medicine, South Korea. Electronic address:

Am J Med Sci 2020 Apr 5. Epub 2020 Apr 5.

Department of Internal Medicine, McMaster University, Hamilton, Canada.

Am J Med Sci 2020 Mar 8. Epub 2020 Mar 8.

Department of Cardiology, Westchester Medical Center and New York Medical College, New York. Electronic address:

Am J Med Sci 2020 Mar 11. Epub 2020 Mar 11.

Department of Medicine, Mackay Medical College, New Taipei City, Taiwan; Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan; MacKay Junior College of Medicine, Nursing and Management, Taipei, Taiwan.

Background: Emphysematous pancreatitis (EP) is an unusual medical emergency that presents with intraparenchymal pancreatic air in the setting of necrotizing infection. We aimed to determine the differences in the epidemiology, etiology, clinical presentation, symptoms and outcome of EP between elderly and nonelderly patients.

Materials And Methods: A PubMed search was performed using the keywords "emphysematous pancreatitis," "gas-forming pancreatitis" and "pancreatitis and pneumoperitoneum" from March 1959 to February 2019. Read More

Am J Med Sci 2020 Mar 13. Epub 2020 Mar 13.

Department of Medicine, University of Minnesota, Minneapolis, Minnesota. Electronic address:

Tuberculosis is a global burden with an unacceptably high mortality rate, especially in low- and middle-income countries. We reported the case of 34-year-old Somali female with no significant risk factors who initially presented with headache and blurred vision. The patient subsequently developed altered mental status and significant vision changes. Read More

Am J Med Sci 2020 Mar 11. Epub 2020 Mar 11.

Institute of Clinical Medicine, School of Medicine; Stem Cell Research Center National Yang-Ming University, Taipei, Taiwan; Department of Medical Research and Department of Orthopedic Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.

Am J Med Sci 2020 Mar 19. Epub 2020 Mar 19.

Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University, Asahikawa, Japan.

Am J Med Sci 2020 Feb 17. Epub 2020 Feb 17.

Division of Nephrology, Department of Medicine, Taipei Veterans General Hospital, School of Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address:

Am J Med Sci 2020 Mar 12. Epub 2020 Mar 12.

Division of Gastroenterology & Hepatology, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey. Electronic address:

Am J Med Sci 2020 May 8;359(5):271-280. Epub 2020 Mar 8.

Department of Epidemiology and Biostatistics, Zhejiang Chinese Medical University, Hangzhou, China. Electronic address:

Background: The association between Alu methylation and risk of cancer remains uncertain. This meta-analysis was conducted to elucidate this issue.

Materials And Methods: PubMed and Web of Science up to December 31, 2018, and the reference lists of studies, as well as those presented in relevant meta-analyses and reviews were systematically searched. Read More

Am J Med Sci 2020 May 14;359(5):308-309. Epub 2019 Dec 14.

Department of Radiology, Affiliated Hospital of Southwest Medical University, LuZhou, SiChuan, China. Electronic address: