12,259 results match your criteria American Journal Of Kidney Diseases[Journal]


Platform Clinical Trials Within Nephrology-Interpreting the Evidence.

Am J Kidney Dis 2022 May 18. Epub 2022 May 18.

The George Institute for Global Health, University of New South Wales, Sydney, Australia; Department of Clinical Pharmacy and Pharmacology, University of Groningen, Groningen, The Netherlands. Electronic address:

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Efficacy of Potassium Supplementation in Hypokalemic Patients Receiving Peritoneal Dialysis: A Randomized Controlled Trial.

Am J Kidney Dis 2022 May 10. Epub 2022 May 10.

Department of Nephrology, Princess Alexandra Hospital, Brisbane, QLD, Australia; Australasian Kidney Trials Network, University of Queensland, Brisbane, Australia; Translational Research Institute, Brisbane, Australia.

Rationale And Objective: Hypokalemia is a common electrolyte abnormality in patients on peritoneal dialysis (PD) and has been associated with increased risks of peritonitis and death. Whether correction of hypokalemia improves these outcomes is unknown.

Study Design: Multicenter, open-label, prospective, randomized controlled trial. Read More

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Performance of the 2021 Race-Free CKD-EPI Creatinine- and Cystatin C-Based Estimated GFR Equations Among Kidney Transplant Recipients.

Am J Kidney Dis 2022 May 12. Epub 2022 May 12.

Department of Medicine (Division of Nephrology) and the Ottawa Hospital Research Institute, University of Ottawa; Ottawa, Ontario, Canada.

Rationale & Objective: Race-free eGFR equations incorporating creatinine with and without cystatin C were recently developed and recommended for routine use. However, the performance of these equations among kidney transplant recipients remains unknown.

Study Design: Cross-sectional study to validate the new race-free CKD-EPI equations (2021 CKD-EPI, 2021 CKD-EPI) among kidney transplant recipients. Read More

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Dialysis Prevalence in Zimbabwe: A Cross-Sectional Descriptive Study.

Am J Kidney Dis 2022 May 13. Epub 2022 May 13.

The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia; Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.

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Metabolic Alkalosis Pathogenesis, Diagnosis, and Treatment: Core Curriculum 2022.

Am J Kidney Dis 2022 May 4. Epub 2022 May 4.

Division of Nephrology, Department of Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico. Electronic address:

Metabolic alkalosis is a widespread acid-base disturbance, especially in hospitalized patients. It is characterized by the primary elevation of serum bicarbonate and arterial pH, along with a compensatory increase in Pco consequent to adaptive hypoventilation. The pathogenesis of metabolic alkalosis involves either a loss of fixed acid or a net accumulation of bicarbonate within the extracellular fluid. Read More

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The Case for a Kidney Emoji.

Am J Kidney Dis 2022 May 2. Epub 2022 May 2.

Section of Nephrology, University of Illinois at Chicago, Chicago, IL.

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Cancer Mortality in People Receiving Dialysis for Kidney Failure: An Australian and New Zealand Cohort Study, 1980-2013.

Am J Kidney Dis 2022 Apr 29. Epub 2022 Apr 29.

The University of Sydney, Faculty of Medicine and Health, Sydney School of Public Health; Centre for Transplant and Renal Research, Westmead Hospital.

Rationale & Objective: Cancer is a significant cause of morbidity in the population with kidney failure, however cancer mortality in people undergoing dialysis is not well described. We sought to compare cancer mortality in people on dialysis for kidney failure to cancer mortality in the general population.

Study Design: A retrospective cohort study using linked health-administrative and dialysis registry data. Read More

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Unmasking Disparities in Kidney Replacement Therapy Among Young Patients-A Call to Action.

Am J Kidney Dis 2022 Apr 27. Epub 2022 Apr 27.

Division of Kidney Medicine, Brigham and Women's Hospital, Boston, Massachusetts; and Harvard Medical School, Boston, Massachusetts.

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Carousel.

Authors:
Sharmeela Saha

Am J Kidney Dis 2022 Apr 26. Epub 2022 Apr 26.

Cincinnati, Ohio. Electronic address:

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Association of Long-term Ambient Fine Particulate Matter (PM) and Incident CKD: A Prospective Cohort Study in China.

Am J Kidney Dis 2022 Apr 22. Epub 2022 Apr 22.

Clinical Research Center, the Third Xiangya Hospital, Central South University, Changsha, China; School of Life Course Sciences, King's College London, London, United Kingdom. Electronic address:

Rationale & Objective: Increasing evidence has linked ambient fine particulate matter (PM) to chronic kidney disease (CKD) but their association has not been fully elucidated, especially in regions with high levels of PM pollution. This study aimed to investigate the long-term association of high PM exposure on incident kidney function in mainland China.

Study Design: Prospective cohort study. Read More

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Preoperative Ionized Magnesium Levels and Risk of Acute Kidney Injury After Cardiac Surgery.

Am J Kidney Dis 2022 Apr 22. Epub 2022 Apr 22.

Department of Internal Medicine, College of Medicine, Institute of Kidney Disease Research, Yonsei University, Seoul, Republic of Korea. Electronic address:

Rationale & Objective: Although postoperative acute kidney injury (AKI) is a serious complication following cardiac surgery, preventive measures are limited. Despite the known association of preoperative low magnesium levels with cardiac surgery-related atrial fibrillation, the association between preoperative magnesium and postoperative AKI has not been fully elucidated. This study evaluated the association between preoperative serum magnesium levels and the development of AKI following cardiac surgery. Read More

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Apixaban Dosing Patterns Versus Warfarin in Patients With Nonvalvular Atrial Fibrillation Receiving Dialysis: A Retrospective Cohort Study.

Am J Kidney Dis 2022 Apr 22. Epub 2022 Apr 22.

Chronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota, USA.

Background & Objectives: Comparison of clinical outcomes across anticoagulation regimens using different apixaban dosing or warfarin is not well-defined in patients with nonvalvular atrial fibrillation (AF) who are receiving dialysis. This study sought to compare these outcomes in a US national cohort of patients with kidney failure receiving maintenance dialysis.

Study Design: Retrospective cohort study. Read More

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A Klotho-Derived Peptide as a Possible Novel Drug to Prevent Kidney Fibrosis.

Am J Kidney Dis 2022 Apr 22. Epub 2022 Apr 22.

Section of Mineral Metabolism, Division of Nephrology, Department of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA.

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Breaking Down the Silence: Call for Action to Address Access Disparities to Transplantation in Indigenous Māori Peoples With Kidney Failure.

Am J Kidney Dis 2022 Apr 22. Epub 2022 Apr 22.

Wellbeing and Preventable Chronic Diseases Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia.

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Principles of Immunosuppression in the Management of Kidney Disease: Core Curriculum 2022.

Am J Kidney Dis 2022 Apr 16. Epub 2022 Apr 16.

Division of Nephrology, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland. Electronic address:

The management of immunosuppression utilized in glomerular diseases requires highly nuanced care. Timely recognition and management of these disorders is essential to mitigate the extent of kidney damage. This involves being cognizant of the various classes of immunosuppression, which includes alkylating agents, antimetabolites, calcineurin inhibitors, anti-CD20 therapy, complement inhibitors, corticosteroids, and intravenous immunoglobulin. Read More

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Maternal Chronic Disease and Congenital Anomalies of the Kidney and Urinary Tract in Offspring: A Japanese Cohort Study.

Am J Kidney Dis 2022 Apr 16. Epub 2022 Apr 16.

Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Research Center for Environment and Developmental Medical Sciences, Kyushu University, Fukuoka, Japan.

Rationale & Objective: Several maternal chronic diseases have been reported as risk factors for congenital anomalies of the kidney and urinary tract (CAKUT) in offspring. However, these investigations used case-control designs, and cases with isolated genitourinary CAKUT (CAKUT) were not distinguished from cases where CAKUT was present with extrarenal congenital anomalies (complicated CAKUT). We examined the association of maternal diseases with isolated and complicated CAKUT in offspring using data from a prospective cohort study. Read More

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Effect of Aspirin on CKD Progression in Older Adults: Secondary Analysis From the ASPREE Randomized Clinical Trial.

Am J Kidney Dis 2022 Apr 14. Epub 2022 Apr 14.

Department of Medicine, Division of Geriatrics, Hennepin Healthcare, Minneapolis, Minnesota, USA; Hennepin Healthcare Research Institute, Minneapolis, Minnesota, USA.

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Cancer Risk and Mortality in Patients With Kidney Disease: A Population-Based Cohort Study.

Am J Kidney Dis 2022 Apr 1. Epub 2022 Apr 1.

Department of Medicine, Division of Nephrology, Unity Health, Toronto, ON, Canada.

Rationale & Objective: Patients with chronic kidney disease (CKD) may be at increased risk for cancer. CKD may also be associated with worse cancer outcomes. This study examined cancer incidence and mortality across the spectrum of CKD. Read More

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Black and White Adults With CKD Hospitalized With Acute Kidney Injury: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.

Am J Kidney Dis 2022 Apr 8. Epub 2022 Apr 8.

Division of Nephrology, Department of Medicine, University of California, San Francisco, CA; Division of Research, Kaiser Permanente Northern California, Oakland, CA.

Rationale & Objective: Few studies have investigated racial disparities in acute kidney injury (AKI), in contrast to the extensive literature on racial differences in the risk of kidney failure. We sought to study potential differences in risk in the setting of chronic kidney disease (CKD).

Study Design: Prospective cohort study. Read More

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Association Between Acute Kidney Injury and Dementia in the Atherosclerosis Risk in Communities (ARIC) Study.

Am J Kidney Dis 2022 Mar 21. Epub 2022 Mar 21.

Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA; Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

Rationale & Objective: Acute kidney injury (AKI) causes biochemical changes in the brain in animal models and is associated with adverse neurological complications in hospitalized patients. The objective of this study was to test the association between AKI and incident dementia in a community-based cohort.

Study Design: Prospective cohort study. Read More

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Shared Decision Making Among Older Adults With Advanced CKD.

Am J Kidney Dis 2022 Mar 26. Epub 2022 Mar 26.

Research on Ethics, Aging, and Community Health (REACH Lab), Tufts University, Medford, MA; Departments of Occupational Therapy and Community Health, Tufts University, Medford, MA.

Rationale & Objective: Older adults with advanced chronic kidney disease (CKD) face difficult decisions about dialysis initiation. Although shared decision-making (SDM) can help align patient preferences and values with treatment options, the extent to which older CKD patients experience SDM remains unknown.

Study Design: A cross-sectional analysis of patient surveys examining decisional readiness, treatment options education, carepartner support, and SDM. Read More

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Association of Uremic Solutes With Cardiovascular Death in Diabetic Kidney Disease.

Am J Kidney Dis 2022 Mar 26. Epub 2022 Mar 26.

Division of Nephrology, Department of Internal Medicine, MetroHealth Campus, and Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, OH. Electronic address:

Rationale And Objective: Cardiovascular disease (CVD) is a major cause of mortality among people with diabetic kidney disease (DKD). The pathophysiology is inadequately explained by traditional CVD risk factors. Three uremic solutes, trimethylamine-N-oxide (TMAO), asymmetric and symmetric dimethylarginine (ADMA, SDMA), have been linked to CVD in kidney failure with renal replacement therapy (KFRT), but data are limited in populations with diabetes and less severe kidney disease. Read More

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The Modified CKiD Study Estimated GFR Equations for Children and Young Adults Under 25 Years of Age: Performance in a European Multicenter Cohort.

Am J Kidney Dis 2022 Mar 25. Epub 2022 Mar 25.

Department of Nephrology-Dialysis-Transplantation, University of Liège (ULg CHU), CHU Sart Tilman, Liège, Belgium; Department of Nephrology-Dialysis-Apheresis, Hopital Universitaire Caremeau, Nimes, France.

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A Patient With Polyuria and Hypercalcemia.

Am J Kidney Dis 2022 04;79(4):A14-A15

Renal-Electrolyte and Hypertension Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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Association of Cardiovascular Health Measures With Cardiovascular Disease and Mortality in CKD: A UK Biobank Study.

Am J Kidney Dis 2022 Mar 18. Epub 2022 Mar 18.

Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, Ministry of Education Key Lab of Environment and Health, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address:

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