9,424 results match your criteria American Journal Of Health-system Pharmacy[Journal]


Apparent interference with extracorporeal membrane oxygenation by liposomal amphotericin B in a patient with disseminated blastomycosis receiving continuous renal replacement therapy.

Am J Health Syst Pharm 2019 Apr 17. Epub 2019 Apr 17.

Drake University College of Pharmacy and Health Sciences, Des Moines, IA.

Purpose: We describe the use of liposomal amphotericin B and amphotericin B deoxycholate in a critically ill patient with pulmonary blastomycosis receiving both venovenous extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT).

Summary: A 50-year-old African American man presented for dyspnea and cough and was noted to have blastomycosis on bronchoscopy. He developed respiratory failure and acute kidney injury, requiring mechanical ventilation, ECMO, and CRRT. Read More

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http://dx.doi.org/10.1093/ajhp/zxz054DOI Listing
April 2019
1 Read

Direct oral anticoagulants versus aspirin for venous thromboembolism prophylaxis after orthopedic surgery.

Am J Health Syst Pharm 2019 Apr 17. Epub 2019 Apr 17.

Houston Methodist Hospital, Houston, TX.

Purpose: The risks of venous thromboembolism (VTE) and bleeding with direct oral anticoagulants (DOACs) and aspirin for thromboprophylaxis after orthopedic surgery were studied.

Methods: A single center, retrospective study was conducted to examine patients who underwent a major orthopedic surgery from 2011 to 2015. The primary endpoint evaluated was the net clinical outcome of bleeding and thrombosis rates between the DOAC and aspirin groups. Read More

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http://dx.doi.org/10.1093/ajhp/zxy080DOI Listing
April 2019
1 Read

Implementation of a grassroots advocacy movement through state and local collaboration.

Am J Health Syst Pharm 2019 Apr 16. Epub 2019 Apr 16.

Department of Pharmacy Mount Sinai West New York, NY.

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http://dx.doi.org/10.1093/ajhp/zxz051DOI Listing

Fostamatinib for the treatment of immune thrombocytopenia in adults.

Am J Health Syst Pharm 2019 Apr 5. Epub 2019 Apr 5.

Department of Hematology/Oncology, Atrium Health, Levine Cancer Institute, Rock Hill, SC.

Purpose: The pharmacology, pharmacokinetics, efficacy, safety, dosing and administration, and place in therapy of fostamatinib, a novel spleen tyrosine kinase inhibitor for the treatment of adult immune thrombocytopenia that has had an insufficient response to a previous treatment are summarized.

Summary: Fostamatinib is an oral inhibitor of spleen tyrosine kinase that is expressed on hematopoietic cells and plays a key role in the accelerated destruction of platelets through Fc-receptor activation. Fostamatinib is indicated for the treatment of adults with immune thrombocytopenia that has had an insufficient response to a previous treatment. Read More

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https://academic.oup.com/ajhp/advance-article/doi/10.1093/aj
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http://dx.doi.org/10.1093/ajhp/zxz052DOI Listing
April 2019
8 Reads

The role of community service in building better pharmacists.

Authors:
Shireen Farzadeh

Am J Health Syst Pharm 2019 Apr 1. Epub 2019 Apr 1.

College of Pharmacy and Health Sciences St. John's University Queens, NY.

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http://dx.doi.org/10.1093/ajhp/zxz037DOI Listing

Practice-enhancing publications about the medication use process in 2017.

Am J Health Syst Pharm 2019 Apr 1. Epub 2019 Apr 1.

University of North Carolina Medical Center, and University of North Carolina at Chapel Hill Eshelman School of Pharmacy, Chapel Hill, NC.

Purpose: This article identifies, prioritizes, and summarizes published literature on the medication use process (MUP) from calendar year 2017 that can impact health-system pharmacists' daily practice. The MUP is the foundational system that provides the framework for safe medication use within the health care environment. The MUP is defined in this article as having the following components: prescribing/transcribing, dispensing, administration, and monitoring. Read More

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http://dx.doi.org/10.1093/ajhp/zxz028DOI Listing

Implementation of a controlled substance collection receptacle.

Am J Health Syst Pharm 2019 Mar 27. Epub 2019 Mar 27.

Pharmacy Health Analytics & Drug Policy University of Chicago Medicine Chicago, IL.

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http://dx.doi.org/10.1093/ajhp/zxz038DOI Listing

Instilling value, quality, and safety through hematology and oncology stewardship.

Am J Health Syst Pharm 2019 Mar 27. Epub 2019 Mar 27.

Oregon Health and Science University Hospital and Clinics, Portland, OR.

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http://dx.doi.org/10.1093/ajhp/zxz036DOI Listing
March 2019
1 Read
2.205 Impact Factor

Drug formulary decision-making: Ethnographic study of 3 pharmacy and therapeutics committees.

Am J Health Syst Pharm 2019 Mar 27. Epub 2019 Mar 27.

Center for Communication and Health, Northwestern University, Chicago, IL.

Purpose: An ethnographic study of 3 pharmacy and therapeutics (P&T) committees was conducted to characterize the process by which evidence is weighted and decisions are made.

Methods: We recorded discussions and conducted an analysis of the transcripts from the 3 P&T committees for a 1-year period. We examined the content and ideas expressed during deliberations and synthesized themes to give a broader picture of the issues arising. Read More

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http://dx.doi.org/10.1093/ajhp/zxz022DOI Listing
March 2019
1 Read

Tiered communication system for a health-system pharmacy department.

Am J Health Syst Pharm 2019 Mar 19. Epub 2019 Mar 19.

Pharmacy Department Children's Mercy Hospital Kansas City, MO.

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http://dx.doi.org/10.1093/ajhp/zxz041DOI Listing

Assessing pharmacist competency after hurricane-related shortages of 0.9% sodium chloride injection.

Authors:
Glenn L Kisch

Am J Health Syst Pharm 2019 Mar 19. Epub 2019 Mar 19.

Department of Pharmacy Franciscan Alliance-Central Indiana Region Indianapolis, IN.

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http://dx.doi.org/10.1093/ajhp/zxz040DOI Listing

Impact of hydrocodone reclassification on analgesic prescribing in the Veterans Health Administration.

Am J Health Syst Pharm 2019 Mar 15. Epub 2019 Mar 15.

Department of Pharmacy Services, Iowa City VA Healthcare System, Iowa City, IA, and Center for Comprehensive Access and Delivery Research and Evaluation, Iowa City VA Healthcare System, Iowa City, IA.

Purpose: The impact of hydrocodone reclassification on analgesic prescribing in the Veterans Health Administration (VHA) was quantified.

Methods: In this retrospective observational study, the volume of opioid medication dispensed was calculated quarterly from October 2011 to September 2015 using national VHA administrative data. Four volume measures were examined (prescription count, tablets dispensed, days' supply dispensed, and unique patients) for 4 opioid groups: HCPs, other opioid combination products, tramadol, and single-agent Schedule II opioids. Read More

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http://dx.doi.org/10.1093/ajhp/zxy090DOI Listing
March 2019
1 Read

Comparative effectiveness of pharmacist care delivery models for hepatitis C clinics.

Am J Health Syst Pharm 2019 Mar 15. Epub 2019 Mar 15.

Lifespan Corporation-Rhode Island Hospital, The Miriam Hospital, Bradley Hospital, Providence, RI, and Lifespan Pharmacy, LLC, Providence, RI.

Purpose: The optimal health care delivery models for providing services to patients with infections caused by hepatitis C virus (HCV) remain unknown. Pharmacist involvement may be a key component of optimal HCV care delivery. We examined the comparative effectiveness of a pharmacist-managed HCV clinic versus a pharmacist-assisted HCV clinic. Read More

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http://dx.doi.org/10.1093/ajhp/zxz034DOI Listing

Process improvement strategy to prepare and administer bacillus Calmette-Guérin (BCG) vaccine in compliance with United States Pharmacopeia (USP) chapter 800 standards.

Am J Health Syst Pharm 2019 Mar 15. Epub 2019 Mar 15.

University of North Carolina Medical Center, Chapel Hill, NC.

Purpose: This case study describes a multidisciplinary initiative to promote the safe use, preparation, and administration of bacillus Calmette-Guérin (BCG) in patients with bladder cancer that is in compliance with United States Pharmacopeia chapter 800.

Summary: After an evaluation of a hospital's medication-use process for the preparation and administration of BCG identified inconsistencies with guideline-based procedures for the safe handling and manipulation of hazardous drug products, a revised medication-use process promoting the inclusion of pharmacy services was developed by pharmacy and urology clinic leaders. Implementation of the enhanced medication-use process included (1) the shift of BCG vaccine preparation from urology clinic nurses to a pharmacy equipped with the appropriate engineering controls for the safe preparation of hazardous product, (2) greater involvement by pharmacists in BCG order justification and verification, and (3) a process that ensured just-in-time preparation and delivery of medication for enhanced patient satisfaction. Read More

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http://dx.doi.org/10.1093/ajhp/zxz027DOI Listing
March 2019
3 Reads

House investigates high drug prices.

Authors:
Kate Traynor

Am J Health Syst Pharm 2019 Mar 14. Epub 2019 Mar 14.

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http://dx.doi.org/10.1093/ajhp/zxz061DOI Listing

Home health service gets assist from pharmacists.

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Am J Health Syst Pharm 2019 Mar 11. Epub 2019 Mar 11.

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http://dx.doi.org/10.1093/ajhp/zxz050DOI Listing

AHA-ASHP sponsored congressional briefing highlights burden of high drug costs, shortages.

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Am J Health Syst Pharm 2019 Mar 11. Epub 2019 Mar 11.

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http://dx.doi.org/10.1093/ajhp/zxz049DOI Listing

Pharmacists examine risks, remedies for burnout.

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Am J Health Syst Pharm 2019 Mar 11. Epub 2019 Mar 11.

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http://dx.doi.org/10.1093/ajhp/zxz042DOI Listing

Impact of a pharmacist-driven education initiative on treatment of asymptomatic bacteriuria.

Am J Health Syst Pharm 2019 Mar 11. Epub 2019 Mar 11.

Department of Pharmacy, Grant Medical Center, OhioHealth, Columbus, OH.

Purpose: The results and methods of a pharmacist-driven multifaceted educational intervention on the appropriate management of asymptomatic bacteriuria (ABU) within an emergency department (ED) are reported.

Methods: A retrospective, single-center cohort study was conducted to evaluate the effects of an educational intervention aimed at reducing the rates of mismanaged ABU within an ED at a Level 1 trauma center. The education involved a multifaceted approach directed by pharmacists and involved a handout and algorithm communicated through in-person discussions, emails, and general distribution. Read More

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http://dx.doi.org/10.1093/ajhp/zxy081DOI Listing

The effect of an interprofessional pain service on nonmalignant pain control.

Am J Health Syst Pharm 2019 Mar 11. Epub 2019 Mar 11.

AxessPointe Community Health Center, Akron, OH.

Purpose: The primary objective of this project is to evaluate an existing interprofessional, nonmalignant pain service by measuring the difference in patient pain scores (numeric rating scale-11) before and after a pharmacist-led pain education class and medication therapy management (MTM) visit. Secondary objectives include determining the percentage of pharmacist recommendations approved, patient satisfaction, and difference in immediate release (IR) and extended release (ER) opioid use before and after enrollment.

Methods: Baseline data was obtained from a retrospective chart review. Read More

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https://academic.oup.com/ajhp/advance-article/doi/10.1093/aj
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http://dx.doi.org/10.1093/ajhp/zxy084DOI Listing
March 2019
18 Reads

VA pharmacists find niche in mental health services.

Authors:
Kate Traynor

Am J Health Syst Pharm 2019 Mar 10. Epub 2019 Mar 10.

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http://dx.doi.org/10.1093/ajhp/zxz048DOI Listing

News brief.

Authors:

Am J Health Syst Pharm 2019 Mar 10. Epub 2019 Mar 10.

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http://dx.doi.org/10.1093/ajhp/zxz047DOI Listing

FDA, National Academies examining opioids for acute pain.

Authors:
Kate Traynor

Am J Health Syst Pharm 2019 Mar 10. Epub 2019 Mar 10.

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https://academic.oup.com/ajhp/advance-article/doi/10.1093/aj
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http://dx.doi.org/10.1093/ajhp/zxz044DOI Listing
March 2019
2 Reads

Implementation of pharmacy morbidity, mortality, and process improvement rounds.

Am J Health Syst Pharm 2019 Mar 10. Epub 2019 Mar 10.

Department of Pharmacy Services Brigham and Women's Hospital Boston, MA.

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http://dx.doi.org/10.1093/ajhp/zxy088DOI Listing

Low-dose corticosteroids in septic shock: Has the pendulum shifted?

Am J Health Syst Pharm 2019 Mar 9. Epub 2019 Mar 9.

University of Saint Joseph School of Pharmacy and Physician Assistant Studies, Hartford, CT, and Department of Pharmacy, Saint Francis Hospital and Medical Center, Hartford, CT.

Purpose: The utility of low-dose corticosteroids in septic shock is reviewed.

Summary: Low-dose corticosteroids are suggested as treatment for septic shock patients who remain hemodynamically unstable despite adequate fluid resuscitation and vasopressor therapy. However, the risks and benefits of corticosteroids are unclear in this patient population. Read More

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http://dx.doi.org/10.1093/ajhp/zxz017DOI Listing
March 2019
3 Reads

Richard Brodeur, former chief of pharmacy for Georgetown, dies at 78.

Authors:
Kate Traynor

Am J Health Syst Pharm 2019 Mar 9. Epub 2019 Mar 9.

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http://dx.doi.org/10.1093/ajhp/zxz045DOI Listing

Tool offers nonopioid options for acute migraine in the emergency department.

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Am J Health Syst Pharm 2019 Mar 5. Epub 2019 Mar 5.

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http://dx.doi.org/10.1093/ajhp/zxz029DOI Listing

Intervention capture helps guide VA pharmacy expansion.

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Am J Health Syst Pharm 2019 Mar 5. Epub 2019 Mar 5.

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http://dx.doi.org/10.1093/ajhp/zxz031DOI Listing

Use of economic predictions to make formulary decisions.

Am J Health Syst Pharm 2019 Feb;76(Supplement_1):S15-S20

Medical University of South Carolina College of Pharmacy, Charleston, SC, MUSC Health, Charleston, SC.

Purpose: The accuracy of cost savings and reimbursement predictions for medications added to an academic medical center formulary was assessed.

Methods: Formulary changes over a 5-year period were reviewed by the investigators. Medications were included if the medication was added to formulary and the monograph included cost savings or reimbursement data that indicated a positive net margin. Read More

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http://dx.doi.org/10.1093/ajhp/zxy024DOI Listing
February 2019

Effect of modifying dose alerts in an electronic health record on frequency of alerts.

Am J Health Syst Pharm 2019 Feb;76(Supplement_1):S1-S8

Department of Pharmacy Practice, Ohio Northern University Raabe College of Pharmacy, Ada, OH.

Purpose: Results of a study to reduce the number of medication order-entry alerts and perceived alert fatigue by optimizing alert logic are reported.

Methods: Data on dosage alerts registered throughout a health system over 2 days per study phase (preintervention and postintervention) were collected from the electronic health record. The 5 medications most frequently associated with dosage alerts during computerized prescriber order entry (CPOE) were evaluated for appropriateness in relation to patient-specific characteristics. Read More

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http://dx.doi.org/10.1093/ajhp/zxy016DOI Listing
February 2019

Impact of clinical pharmacy specialists on glycemic control in veterans with type 2 diabetes.

Am J Health Syst Pharm 2019 Feb;76(Supplement_1):S9-S14

Cincinnati VA Medical Center, Cincinnati, OH.

Purpose: The results of a study to determine the impact that Patient Aligned Care Team clinical pharmacy specialists (CPSs) have in improving glycemic control among veterans with type 2 diabetes are reported.

Methods: Reductions in glycosylated hemoglobin (HbA1c) values in diabetic patients are associated with improved outcomes related to vascular complications. Current diabetes management strategies at the Cincinnati Veteran Affairs Medical Center (VAMC) involve a multidisciplinary approach that includes visits with a CPS by veterans referred by a primary care provider. Read More

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http://dx.doi.org/10.1093/ajhp/zxy015DOI Listing
February 2019
2 Reads

Variability in training, practice, and prioritization of services among emergency medicine pharmacists.

Am J Health Syst Pharm 2019 Feb;76(Supplement_1):S21-S27

University of Kentucky HealthCare Pharmacy Services, Lexington, KY.

Purpose: The purpose of this survey-based research project is to identify factors, including prior training, institution demographics, and pharmacist prioritization of services that may impact variability in practice among emergency medicine (EM) pharmacists.

Methods: An electronic survey was available for 6 weeks. Participants were contacted through professional membership directories. Read More

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https://academic.oup.com/ajhp/article/76/Supplement_1/S21/53
Publisher Site
http://dx.doi.org/10.1093/ajhp/zxy049DOI Listing
February 2019
4 Reads

New drugs and dosage forms.

Authors:

Am J Health Syst Pharm 2019 Feb;76(5):261

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http://dx.doi.org/10.1093/ajhp/zxz003DOI Listing
February 2019

Stakeholders describe drug shortage challenges.

Authors:
Kate Traynor

Am J Health Syst Pharm 2019 Feb;76(5):259-260

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http://dx.doi.org/10.1093/ajhp/zxy077DOI Listing
February 2019

Hopes are high for collaborative practice in Florida.

Authors:
Kate Traynor

Am J Health Syst Pharm 2019 Feb;76(5):260-262

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http://dx.doi.org/10.1093/ajhp/zxy076DOI Listing
February 2019

Safety of high-dose intravenous labetalol in hypertensive crisis.

Am J Health Syst Pharm 2019 Feb;76(5):286-292

Department of Surgery, St. Joseph Mercy Hospital, Ann Arbor, MI.

Purpose: The study assesses the safety of high-dose intravenous (i.v.) labetalol in adults. Read More

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http://dx.doi.org/10.1093/ajhp/zxy045DOI Listing
February 2019
2 Reads

Using a spare medication vial to store multiple medications: A potentially fatal in-home medication error.

Am J Health Syst Pharm 2019 02;76(5):264-265

Maryland Poison Center Department of Pharmacy Practice and Science University of Maryland School of Pharmacy Baltimore, MD.

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http://dx.doi.org/10.1093/ajhp/zxy037DOI Listing
February 2019

Adverse drug reactions in the Veterans Affairs healthcare system: Frequency, severity, and causative medications analyzed by patient age.

Am J Health Syst Pharm 2019 Feb;76(5):312-319

Veterans Affairs Center for Medication Safety/Pharmacy Benefits Management Services, Hines, IL.

Purpose: Adverse drug events (ADEs) in the U.S. Department of Veterans Affairs (VA) were evaluated, and differences in age group report rates and reported medications in different age groups were assessed. Read More

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http://dx.doi.org/10.1093/ajhp/zxy059DOI Listing
February 2019
2 Reads

Midostaurin for the management of FLT3-mutated acute myeloid leukemia and advanced systemic mastocytosis.

Am J Health Syst Pharm 2019 02;76(5):268-274

Department of Pharmaceutical Care, University of Iowa Hospitals & Clinics, Iowa City, IA.

Purpose: This article reviews the pharmacology, efficacy, safety, cost, and future directions of midostaurin for the treatment of acute myeloid leukemia (AML), aggressive systemic mastocytosis, systemic mastocytosis with associated hematological neoplasm, and mast cell leukemia, collectively known as advanced systemic mastocytosis (SM).

Summary: Midostaurin was approved by the U.S. Read More

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http://dx.doi.org/10.1093/ajhp/zxy050DOI Listing
February 2019
2 Reads

Advancing pharmacy practice by reducing gaps in pharmacogenetic education.

Am J Health Syst Pharm 2019 Feb;76(5):320-326

Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, UT.

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http://dx.doi.org/10.1093/ajhp/zxy066DOI Listing
February 2019
3 Reads

Use of a tablet computer application to engage patients in updating their medication list.

Am J Health Syst Pharm 2019 Feb;76(5):293-300

SAI Interactive, Inc., Chattanooga, TN.

Purpose: Failure to obtain an accurate medication history can adversely affect patient care in the emergency department (ED) and propagate errors into the inpatient and outpatient settings. Obtaining an accurate medication history in the ED is challenging, however, due to limited time, a suboptimal environment for patient interaction, and inadequate information in the electronic health record (EHR). This article describes the development and initial evaluation of the PictureRx Medication History Application, a tablet computer-based program that queries patients' prescription fill data from the Surescripts Medication History service and renders it graphically for review and editing at the point of care. Read More

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https://academic.oup.com/ajhp/article/76/5/293/5310470
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http://dx.doi.org/10.1093/ajhp/zxy047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369717PMC
February 2019
4 Reads

Administration of crushed maraviroc via percutaneous gastrostomy tube in a patient with human immunodeficiency virus and progressive multifocal leukoencephalopathy.

Am J Health Syst Pharm 2019 02;76(5):265-267

Department of Pharmacy Virginia Commonwealth University Health Richmond, VA.

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http://dx.doi.org/10.1093/ajhp/zxy046DOI Listing
February 2019
1 Read

Appointments.

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Am J Health Syst Pharm 2019 Feb;76(4):199

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http://dx.doi.org/10.1093/ajhp/zxy093DOI Listing
February 2019

News brief.

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Am J Health Syst Pharm 2019 Feb;76(4):199

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http://dx.doi.org/10.1093/ajhp/zxy092DOI Listing
February 2019

After hurricane, mobile pharmacy helps Florida veterans.

Authors:
Kate Traynor

Am J Health Syst Pharm 2019 Feb;76(4):198-199

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http://dx.doi.org/10.1093/ajhp/zxy078DOI Listing
February 2019

New drugs and dosage forms.

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Am J Health Syst Pharm 2019 Feb;76(4):198

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http://dx.doi.org/10.1093/ajhp/zxy091DOI Listing
February 2019

Professional Policy Approved by the 2018 ASHP November Virtual House of Delegates.

Authors:

Am J Health Syst Pharm 2019 Feb;76(4):254

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http://dx.doi.org/10.1093/ajhp/zxy074DOI Listing
February 2019

CPIC secures $5 million for pharmacogenetics work.

Authors:
Kate Traynor

Am J Health Syst Pharm 2019 Feb;76(4):197

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http://dx.doi.org/10.1093/ajhp/zxy075DOI Listing
February 2019

Quality indicators to measure the effect of opioid stewardship interventions in hospital and emergency department settings.

Am J Health Syst Pharm 2019 Feb;76(4):225-235

Department of Neurology, Houston Methodist Hospital, Houston, TX.

Purpose: The purpose of this project was to develop a set of valid and feasible quality indicators used to track opioid stewardship efforts in hospital and emergency department settings.

Methods: Candidate quality indicators were extracted from published literature. Feasibility screening excluded quality indicators that cannot be reliably extracted from the electronic health record or that are irrelevant to pain management in the hospital and emergency department settings. Read More

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http://dx.doi.org/10.1093/ajhp/zxy042DOI Listing
February 2019

Nimble leadership: A framework for future success.

Am J Health Syst Pharm 2019 Feb;76(4):221-224

Cardinal Health Innovative Delivery Solutions, Wilkes-Barre, PA.

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http://dx.doi.org/10.1093/ajhp/zxy044DOI Listing
February 2019